Motif ID: BCL6B
Z-value: 1.092
Transcription factors associated with BCL6B:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| BCL6B | ENSG00000161940.6 | BCL6B |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 5.2 | GO:0060414 | aorta development(GO:0035904) aorta morphogenesis(GO:0035909) aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 0.6 | 4.8 | GO:0007598 | blood coagulation, extrinsic pathway(GO:0007598) |
| 0.3 | 0.8 | GO:0002035 | renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) brain renin-angiotensin system(GO:0002035) response to stimulus involved in regulation of muscle adaptation(GO:0014874) astrocyte activation(GO:0048143) |
| 0.3 | 0.8 | GO:0006740 | NADPH regeneration(GO:0006740) |
| 0.3 | 3.0 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.2 | 5.8 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.2 | 0.7 | GO:0060370 | susceptibility to T cell mediated cytotoxicity(GO:0060370) |
| 0.2 | 1.5 | GO:0030277 | epithelial structure maintenance(GO:0010669) maintenance of gastrointestinal epithelium(GO:0030277) |
| 0.1 | 0.8 | GO:0016264 | gap junction assembly(GO:0016264) |
| 0.1 | 0.7 | GO:2000172 | regulation of branching morphogenesis of a nerve(GO:2000172) |
| 0.1 | 0.7 | GO:0090292 | nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292) |
| 0.1 | 0.8 | GO:0001706 | endoderm formation(GO:0001706) |
| 0.1 | 1.0 | GO:0060638 | mesenchymal-epithelial cell signaling(GO:0060638) |
| 0.1 | 0.1 | GO:0014889 | muscle atrophy(GO:0014889) |
| 0.1 | 0.2 | GO:0006922 | obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922) |
| 0.1 | 0.2 | GO:0002428 | antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428) antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481) |
| 0.1 | 0.2 | GO:0071318 | cellular response to ATP(GO:0071318) |
| 0.1 | 0.8 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 0.1 | 0.6 | GO:1901984 | negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757) |
| 0.0 | 1.1 | GO:0006656 | phosphatidylcholine biosynthetic process(GO:0006656) |
| 0.0 | 0.1 | GO:0046968 | peptide antigen transport(GO:0046968) |
| 0.0 | 0.3 | GO:0042159 | lipoprotein catabolic process(GO:0042159) |
| 0.0 | 0.9 | GO:0007172 | signal complex assembly(GO:0007172) |
| 0.0 | 0.2 | GO:0046121 | deoxyribonucleoside catabolic process(GO:0046121) |
| 0.0 | 0.1 | GO:0046621 | negative regulation of organ growth(GO:0046621) |
| 0.0 | 0.3 | GO:0021952 | central nervous system projection neuron axonogenesis(GO:0021952) |
| 0.0 | 0.2 | GO:0045329 | amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329) |
| 0.0 | 0.2 | GO:0007351 | tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595) |
| 0.0 | 0.3 | GO:0006107 | oxaloacetate metabolic process(GO:0006107) |
| 0.0 | 0.5 | GO:0034199 | activation of protein kinase A activity(GO:0034199) |
| 0.0 | 0.3 | GO:0016601 | Rac protein signal transduction(GO:0016601) |
| 0.0 | 0.3 | GO:0001782 | B cell homeostasis(GO:0001782) |
| 0.0 | 0.4 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.0 | 0.1 | GO:0006600 | creatine metabolic process(GO:0006600) |
| 0.0 | 0.1 | GO:0007210 | serotonin receptor signaling pathway(GO:0007210) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 3.3 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.3 | 3.0 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.2 | 3.0 | GO:0098647 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.1 | 0.7 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.0 | 0.8 | GO:0005922 | connexon complex(GO:0005922) |
| 0.0 | 0.6 | GO:0019908 | nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908) |
| 0.0 | 1.1 | GO:0016528 | sarcoplasm(GO:0016528) |
| 0.0 | 0.6 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 4.1 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.0 | 0.2 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.0 | 0.3 | GO:0030669 | clathrin-coated endocytic vesicle membrane(GO:0030669) |
| 0.0 | 0.5 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.0 | 0.2 | GO:0019897 | extrinsic component of plasma membrane(GO:0019897) |
| 0.0 | 0.3 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.0 | 1.0 | GO:0005604 | basement membrane(GO:0005604) |
| 0.0 | 0.5 | GO:0042645 | mitochondrial nucleoid(GO:0042645) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 5.2 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 0.3 | 0.8 | GO:0004345 | glucose-6-phosphate dehydrogenase activity(GO:0004345) |
| 0.3 | 1.1 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.2 | 0.8 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
| 0.2 | 1.0 | GO:0045545 | syndecan binding(GO:0045545) |
| 0.2 | 0.8 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
| 0.1 | 3.3 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.1 | 5.8 | GO:0005518 | collagen binding(GO:0005518) |
| 0.1 | 0.3 | GO:0004613 | phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613) |
| 0.1 | 0.2 | GO:0004139 | deoxyribose-phosphate aldolase activity(GO:0004139) |
| 0.1 | 6.5 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.1 | 0.2 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
| 0.1 | 1.7 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.0 | 0.4 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.0 | 0.4 | GO:0046790 | virion binding(GO:0046790) |
| 0.0 | 0.3 | GO:0030229 | very-low-density lipoprotein particle receptor activity(GO:0030229) |
| 0.0 | 0.6 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.0 | 0.1 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
| 0.0 | 0.9 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.0 | 0.5 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.0 | 3.0 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 0.5 | GO:0043499 | obsolete eukaryotic cell surface binding(GO:0043499) |
| 0.0 | 0.2 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.0 | 0.1 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.0 | 0.1 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.0 | 0.7 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.0 | 0.2 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 0.8 | GO:0015297 | antiporter activity(GO:0015297) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.2 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 0.7 | ST_GA12_PATHWAY | G alpha 12 Pathway |
