Motif ID: BPTF
Z-value: 2.111
Transcription factors associated with BPTF:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
BPTF | ENSG00000171634.12 | BPTF |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.6 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
0.5 | 1.5 | GO:0007079 | mitotic chromosome movement towards spindle pole(GO:0007079) chromosome movement towards spindle pole(GO:0051305) |
0.4 | 1.6 | GO:0031340 | positive regulation of vesicle fusion(GO:0031340) |
0.4 | 1.1 | GO:0045719 | negative regulation of glycogen biosynthetic process(GO:0045719) |
0.4 | 2.2 | GO:1901503 | ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503) |
0.3 | 1.0 | GO:0034036 | purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428) |
0.3 | 2.3 | GO:0051901 | positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181) |
0.3 | 0.9 | GO:0060012 | synaptic transmission, glycinergic(GO:0060012) |
0.3 | 0.8 | GO:0060599 | lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) |
0.3 | 2.5 | GO:0071692 | sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116) |
0.3 | 1.1 | GO:0042118 | endothelial cell activation(GO:0042118) |
0.2 | 0.5 | GO:0048286 | lung alveolus development(GO:0048286) |
0.2 | 1.0 | GO:0009956 | radial pattern formation(GO:0009956) |
0.2 | 0.9 | GO:0046121 | deoxyribonucleoside catabolic process(GO:0046121) |
0.2 | 1.3 | GO:0016080 | synaptic vesicle targeting(GO:0016080) |
0.2 | 1.3 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672) |
0.2 | 0.9 | GO:0006154 | adenosine catabolic process(GO:0006154) |
0.2 | 0.6 | GO:0071529 | cementum mineralization(GO:0071529) |
0.2 | 0.6 | GO:0006530 | asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345) |
0.2 | 0.7 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
0.2 | 1.0 | GO:0032460 | negative regulation of protein oligomerization(GO:0032460) negative regulation of protein homooligomerization(GO:0032463) |
0.2 | 1.8 | GO:0051497 | negative regulation of stress fiber assembly(GO:0051497) |
0.2 | 0.8 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
0.2 | 0.5 | GO:1901419 | regulation of response to alcohol(GO:1901419) |
0.2 | 2.1 | GO:0050718 | positive regulation of interleukin-1 beta secretion(GO:0050718) |
0.2 | 0.6 | GO:0051503 | purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) |
0.2 | 0.8 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
0.2 | 1.8 | GO:0048488 | synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583) |
0.1 | 0.3 | GO:0044854 | membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836) membrane assembly(GO:0071709) |
0.1 | 0.5 | GO:0051563 | smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) |
0.1 | 0.4 | GO:0019521 | aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521) |
0.1 | 1.9 | GO:0033687 | osteoblast proliferation(GO:0033687) |
0.1 | 0.4 | GO:1901970 | positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101) |
0.1 | 1.8 | GO:0050872 | white fat cell differentiation(GO:0050872) |
0.1 | 0.1 | GO:0060046 | regulation of acrosome reaction(GO:0060046) |
0.1 | 0.1 | GO:0050653 | chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653) |
0.1 | 0.5 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
0.1 | 0.9 | GO:0003065 | regulation of heart rate by chemical signal(GO:0003062) positive regulation of heart rate by epinephrine(GO:0003065) |
0.1 | 0.7 | GO:0001514 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
0.1 | 0.3 | GO:0042268 | regulation of cytolysis(GO:0042268) |
0.1 | 0.5 | GO:0035405 | histone-threonine phosphorylation(GO:0035405) |
0.1 | 0.4 | GO:0031643 | positive regulation of myelination(GO:0031643) |
0.1 | 0.3 | GO:0002025 | vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025) |
0.1 | 0.9 | GO:0009249 | protein lipoylation(GO:0009249) |
0.1 | 0.5 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
0.1 | 0.6 | GO:0006880 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
0.1 | 0.7 | GO:0051383 | kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383) |
0.1 | 0.3 | GO:0021570 | rhombomere 4 development(GO:0021570) |
0.1 | 0.9 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
0.1 | 0.5 | GO:0045722 | positive regulation of gluconeogenesis(GO:0045722) |
0.1 | 0.8 | GO:0050650 | chondroitin sulfate proteoglycan biosynthetic process(GO:0050650) |
0.1 | 0.4 | GO:0046881 | positive regulation of gonadotropin secretion(GO:0032278) positive regulation of follicle-stimulating hormone secretion(GO:0046881) |
0.1 | 0.5 | GO:0006931 | substrate-dependent cell migration, cell attachment to substrate(GO:0006931) |
0.1 | 9.9 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
0.1 | 1.7 | GO:0009812 | flavonoid metabolic process(GO:0009812) |
0.1 | 0.6 | GO:0045647 | negative regulation of erythrocyte differentiation(GO:0045647) |
0.1 | 0.7 | GO:0043306 | positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306) |
0.1 | 0.7 | GO:0045329 | amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329) |
0.1 | 0.8 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
0.1 | 1.0 | GO:0000052 | citrulline metabolic process(GO:0000052) |
0.1 | 0.8 | GO:0007130 | synaptonemal complex assembly(GO:0007130) |
0.1 | 0.1 | GO:0034244 | negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) |
0.1 | 0.4 | GO:0060710 | chorio-allantoic fusion(GO:0060710) |
0.1 | 0.5 | GO:0031641 | regulation of myelination(GO:0031641) |
0.1 | 0.3 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
0.1 | 0.2 | GO:0010248 | establishment or maintenance of transmembrane electrochemical gradient(GO:0010248) |
0.1 | 0.3 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
0.1 | 0.7 | GO:0090292 | nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292) |
0.1 | 0.2 | GO:0032074 | negative regulation of nuclease activity(GO:0032074) |
0.1 | 0.4 | GO:0042693 | muscle cell fate commitment(GO:0042693) |
0.1 | 0.3 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
0.1 | 0.6 | GO:0008354 | germ cell migration(GO:0008354) |
0.1 | 0.2 | GO:0035269 | protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502) |
0.1 | 0.2 | GO:0001575 | globoside metabolic process(GO:0001575) |
0.1 | 0.2 | GO:0046208 | spermine catabolic process(GO:0046208) |
0.1 | 2.3 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
0.1 | 0.1 | GO:0002326 | B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152) |
0.1 | 0.1 | GO:0014041 | regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429) |
0.1 | 0.2 | GO:0002318 | myeloid progenitor cell differentiation(GO:0002318) |
0.1 | 0.3 | GO:0031665 | negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665) |
0.1 | 0.5 | GO:0032727 | positive regulation of interferon-alpha production(GO:0032727) |
0.1 | 0.2 | GO:0045760 | positive regulation of action potential(GO:0045760) |
0.1 | 0.2 | GO:0045199 | maintenance of epithelial cell apical/basal polarity(GO:0045199) |
0.1 | 0.2 | GO:0051451 | myoblast migration(GO:0051451) |
0.1 | 0.3 | GO:0040001 | establishment of mitotic spindle localization(GO:0040001) |
0.1 | 0.3 | GO:0051665 | membrane raft localization(GO:0051665) |
0.1 | 0.4 | GO:0050689 | negative regulation of defense response to virus by host(GO:0050689) |
0.1 | 0.3 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
0.1 | 0.7 | GO:0048843 | negative regulation of axon extension involved in axon guidance(GO:0048843) |
0.1 | 0.6 | GO:0006702 | androgen biosynthetic process(GO:0006702) |
0.0 | 0.1 | GO:0035751 | lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751) |
0.0 | 0.2 | GO:0032497 | detection of lipopolysaccharide(GO:0032497) |
0.0 | 1.1 | GO:0008347 | glial cell migration(GO:0008347) |
0.0 | 0.4 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
0.0 | 0.1 | GO:0033278 | cell proliferation in midbrain(GO:0033278) |
0.0 | 0.7 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
0.0 | 0.1 | GO:0060370 | susceptibility to T cell mediated cytotoxicity(GO:0060370) |
0.0 | 0.3 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
0.0 | 0.1 | GO:0001907 | cytolysis by symbiont of host cells(GO:0001897) killing by symbiont of host cells(GO:0001907) hemolysis by symbiont of host erythrocytes(GO:0019836) disruption by symbiont of host cell(GO:0044004) hemolysis in other organism(GO:0044179) cytolysis in other organism(GO:0051715) cytolysis in other organism involved in symbiotic interaction(GO:0051801) hemolysis in other organism involved in symbiotic interaction(GO:0052331) |
0.0 | 5.9 | GO:0032259 | methylation(GO:0032259) |
0.0 | 0.4 | GO:0015862 | uridine transport(GO:0015862) |
0.0 | 0.3 | GO:0070245 | positive regulation of thymocyte apoptotic process(GO:0070245) |
0.0 | 0.3 | GO:0032057 | negative regulation of translational initiation in response to stress(GO:0032057) |
0.0 | 0.3 | GO:0043029 | T cell homeostasis(GO:0043029) |
0.0 | 0.7 | GO:0006198 | cAMP catabolic process(GO:0006198) |
0.0 | 0.1 | GO:0045838 | CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361) positive regulation of regulatory T cell differentiation(GO:0045591) positive regulation of membrane potential(GO:0045838) |
0.0 | 0.4 | GO:0031122 | cytoplasmic microtubule organization(GO:0031122) |
0.0 | 0.1 | GO:0006167 | AMP biosynthetic process(GO:0006167) |
0.0 | 0.1 | GO:1990170 | detoxification of cadmium ion(GO:0071585) stress response to cadmium ion(GO:1990170) |
0.0 | 0.3 | GO:0032916 | transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916) |
0.0 | 0.3 | GO:0016098 | monoterpenoid metabolic process(GO:0016098) |
0.0 | 0.2 | GO:0002328 | pro-B cell differentiation(GO:0002328) |
0.0 | 0.4 | GO:0046697 | decidualization(GO:0046697) |
0.0 | 0.2 | GO:0003070 | age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) |
0.0 | 0.2 | GO:0045650 | negative regulation of macrophage differentiation(GO:0045650) |
0.0 | 0.4 | GO:0060216 | definitive hemopoiesis(GO:0060216) |
0.0 | 0.3 | GO:0051957 | positive regulation of amino acid transport(GO:0051957) |
0.0 | 0.1 | GO:0001941 | postsynaptic membrane organization(GO:0001941) |
0.0 | 0.2 | GO:0016322 | neuron remodeling(GO:0016322) |
0.0 | 0.2 | GO:0007525 | somatic muscle development(GO:0007525) |
0.0 | 1.1 | GO:0018208 | peptidyl-proline modification(GO:0018208) |
0.0 | 0.1 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
0.0 | 0.3 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
0.0 | 0.1 | GO:0045835 | negative regulation of meiotic nuclear division(GO:0045835) |
0.0 | 0.8 | GO:0045026 | plasma membrane fusion(GO:0045026) |
0.0 | 0.2 | GO:0006772 | thiamine metabolic process(GO:0006772) |
0.0 | 0.4 | GO:0060391 | positive regulation of SMAD protein import into nucleus(GO:0060391) |
0.0 | 0.5 | GO:0008635 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635) |
0.0 | 0.1 | GO:0009221 | pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221) |
0.0 | 0.2 | GO:0016559 | peroxisome fission(GO:0016559) |
0.0 | 0.4 | GO:0043403 | skeletal muscle tissue regeneration(GO:0043403) |
0.0 | 0.5 | GO:0048207 | vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114) |
0.0 | 0.2 | GO:0006651 | diacylglycerol biosynthetic process(GO:0006651) |
0.0 | 0.1 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
0.0 | 0.4 | GO:0006491 | N-glycan processing(GO:0006491) |
0.0 | 0.4 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
0.0 | 0.5 | GO:0000303 | response to superoxide(GO:0000303) |
0.0 | 1.4 | GO:1900181 | negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein localization to nucleus(GO:1900181) negative regulation of protein import(GO:1904590) |
0.0 | 0.1 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
0.0 | 0.2 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
0.0 | 0.5 | GO:1901224 | activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224) |
0.0 | 0.1 | GO:0007507 | heart development(GO:0007507) |
0.0 | 0.2 | GO:2000124 | cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124) |
0.0 | 0.1 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
0.0 | 0.1 | GO:1904358 | positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358) |
0.0 | 0.1 | GO:0002689 | negative regulation of leukocyte chemotaxis(GO:0002689) |
0.0 | 0.4 | GO:0031032 | actomyosin structure organization(GO:0031032) |
0.0 | 0.1 | GO:0048619 | embryonic hindgut morphogenesis(GO:0048619) |
0.0 | 0.1 | GO:0018874 | benzoate metabolic process(GO:0018874) |
0.0 | 0.2 | GO:0045542 | positive regulation of cholesterol biosynthetic process(GO:0045542) |
0.0 | 0.1 | GO:0044413 | evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834) |
0.0 | 0.9 | GO:0030866 | cortical cytoskeleton organization(GO:0030865) cortical actin cytoskeleton organization(GO:0030866) |
0.0 | 4.8 | GO:0006414 | translational elongation(GO:0006414) |
0.0 | 0.1 | GO:0042262 | DNA protection(GO:0042262) |
0.0 | 0.1 | GO:0031936 | regulation of chromatin silencing(GO:0031935) negative regulation of chromatin silencing(GO:0031936) |
0.0 | 0.1 | GO:0007616 | long-term memory(GO:0007616) |
0.0 | 0.2 | GO:0006622 | protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666) |
0.0 | 0.0 | GO:0014889 | muscle atrophy(GO:0014889) |
0.0 | 0.5 | GO:0007520 | myoblast fusion(GO:0007520) |
0.0 | 0.3 | GO:0043124 | negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124) |
0.0 | 0.5 | GO:0006972 | hyperosmotic response(GO:0006972) |
0.0 | 0.0 | GO:1902913 | positive regulation of neuroepithelial cell differentiation(GO:1902913) |
0.0 | 0.1 | GO:0010842 | retina layer formation(GO:0010842) |
0.0 | 0.2 | GO:0045040 | outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040) |
0.0 | 0.2 | GO:0000301 | retrograde transport, vesicle recycling within Golgi(GO:0000301) |
0.0 | 0.5 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
0.0 | 0.1 | GO:0021799 | cerebral cortex radially oriented cell migration(GO:0021799) |
0.0 | 0.1 | GO:0033033 | negative regulation of myeloid cell apoptotic process(GO:0033033) |
0.0 | 0.0 | GO:0097352 | autophagosome maturation(GO:0097352) |
0.0 | 0.1 | GO:0061084 | regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084) negative regulation of protein folding(GO:1903333) |
0.0 | 0.1 | GO:0035058 | nonmotile primary cilium assembly(GO:0035058) |
0.0 | 0.3 | GO:0007567 | parturition(GO:0007567) |
0.0 | 0.1 | GO:0007614 | short-term memory(GO:0007614) |
0.0 | 0.1 | GO:0006477 | protein sulfation(GO:0006477) |
0.0 | 0.2 | GO:0051014 | actin filament severing(GO:0051014) |
0.0 | 0.3 | GO:0015012 | heparan sulfate proteoglycan biosynthetic process(GO:0015012) |
0.0 | 1.1 | GO:0071377 | cellular response to glucagon stimulus(GO:0071377) |
0.0 | 0.4 | GO:0060765 | regulation of androgen receptor signaling pathway(GO:0060765) |
0.0 | 0.2 | GO:0048712 | negative regulation of astrocyte differentiation(GO:0048712) |
0.0 | 0.9 | GO:0030521 | androgen receptor signaling pathway(GO:0030521) |
0.0 | 0.1 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
0.0 | 0.3 | GO:0044550 | secondary metabolite biosynthetic process(GO:0044550) |
0.0 | 0.1 | GO:0045065 | cytotoxic T cell differentiation(GO:0045065) |
0.0 | 0.2 | GO:0042572 | retinol metabolic process(GO:0042572) |
0.0 | 0.1 | GO:0030277 | epithelial structure maintenance(GO:0010669) maintenance of gastrointestinal epithelium(GO:0030277) |
0.0 | 0.1 | GO:2000831 | renin-angiotensin regulation of aldosterone production(GO:0002018) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) obsolete regulation of natriuresis(GO:0003078) positive regulation of NAD(P)H oxidase activity(GO:0033864) corticosteroid hormone secretion(GO:0035930) mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846) regulation of mineralocorticoid secretion(GO:2000855) regulation of aldosterone secretion(GO:2000858) |
0.0 | 0.0 | GO:0042769 | DNA damage response, detection of DNA damage(GO:0042769) |
0.0 | 0.1 | GO:0060394 | negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394) |
0.0 | 0.1 | GO:0000012 | single strand break repair(GO:0000012) |
0.0 | 0.3 | GO:0032098 | regulation of appetite(GO:0032098) |
0.0 | 0.1 | GO:0031536 | positive regulation of exit from mitosis(GO:0031536) |
0.0 | 0.5 | GO:0016575 | histone deacetylation(GO:0016575) |
0.0 | 0.1 | GO:0032754 | positive regulation of interleukin-13 production(GO:0032736) positive regulation of interleukin-5 production(GO:0032754) |
0.0 | 0.2 | GO:0007032 | endosome organization(GO:0007032) |
0.0 | 0.1 | GO:0035590 | purinergic nucleotide receptor signaling pathway(GO:0035590) |
0.0 | 0.0 | GO:0061117 | negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117) |
0.0 | 0.1 | GO:0033572 | ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512) |
0.0 | 0.1 | GO:0051877 | pigment granule aggregation in cell center(GO:0051877) |
0.0 | 0.2 | GO:0031000 | response to caffeine(GO:0031000) |
0.0 | 0.0 | GO:0002092 | positive regulation of receptor internalization(GO:0002092) |
0.0 | 0.2 | GO:1902591 | vesicle coating(GO:0006901) single-organism membrane budding(GO:1902591) |
0.0 | 0.0 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) |
0.0 | 0.1 | GO:0009313 | oligosaccharide catabolic process(GO:0009313) |
0.0 | 0.1 | GO:0009642 | response to light intensity(GO:0009642) |
0.0 | 0.3 | GO:0030224 | monocyte differentiation(GO:0030224) |
0.0 | 0.5 | GO:0030520 | intracellular estrogen receptor signaling pathway(GO:0030520) |
0.0 | 0.1 | GO:0015802 | basic amino acid transport(GO:0015802) |
0.0 | 0.1 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
0.0 | 0.3 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
0.0 | 0.4 | GO:0031532 | actin cytoskeleton reorganization(GO:0031532) |
0.0 | 0.0 | GO:0051984 | positive regulation of chromosome segregation(GO:0051984) |
0.0 | 0.0 | GO:0072677 | eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677) |
0.0 | 0.0 | GO:0060081 | membrane hyperpolarization(GO:0060081) |
0.0 | 0.2 | GO:0007026 | microtubule depolymerization(GO:0007019) negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114) |
0.0 | 0.1 | GO:0009301 | snRNA transcription(GO:0009301) |
0.0 | 0.1 | GO:0032026 | response to magnesium ion(GO:0032026) |
0.0 | 0.2 | GO:0018214 | peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214) |
0.0 | 0.4 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
0.0 | 0.1 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
0.0 | 0.7 | GO:0042059 | negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185) |
0.0 | 0.0 | GO:0060049 | regulation of protein ADP-ribosylation(GO:0010835) negative regulation of protein ADP-ribosylation(GO:0010836) regulation of protein glycosylation(GO:0060049) negative regulation of protein glycosylation(GO:0060051) |
0.0 | 0.1 | GO:0046487 | glyoxylate metabolic process(GO:0046487) |
0.0 | 0.5 | GO:0070374 | positive regulation of ERK1 and ERK2 cascade(GO:0070374) |
0.0 | 0.5 | GO:0030307 | positive regulation of cell growth(GO:0030307) |
0.0 | 0.0 | GO:0043438 | acetoacetic acid metabolic process(GO:0043438) acetoacetic acid biosynthetic process(GO:0043441) |
0.0 | 0.1 | GO:0015705 | iodide transport(GO:0015705) |
0.0 | 0.9 | GO:0016197 | endosomal transport(GO:0016197) |
0.0 | 0.3 | GO:0050771 | negative regulation of axonogenesis(GO:0050771) |
0.0 | 0.4 | GO:0048010 | vascular endothelial growth factor receptor signaling pathway(GO:0048010) |
0.0 | 0.5 | GO:0019722 | calcium-mediated signaling(GO:0019722) |
0.0 | 0.2 | GO:0007030 | Golgi organization(GO:0007030) |
0.0 | 0.3 | GO:0006826 | iron ion transport(GO:0006826) |
0.0 | 0.3 | GO:0046907 | intracellular transport(GO:0046907) |
0.0 | 0.0 | GO:0010919 | regulation of inositol phosphate biosynthetic process(GO:0010919) positive regulation of inositol phosphate biosynthetic process(GO:0060732) |
0.0 | 0.1 | GO:1903513 | retrograde protein transport, ER to cytosol(GO:0030970) protein exit from endoplasmic reticulum(GO:0032527) endoplasmic reticulum to cytosol transport(GO:1903513) |
0.0 | 0.2 | GO:0007178 | transmembrane receptor protein serine/threonine kinase signaling pathway(GO:0007178) |
0.0 | 0.8 | GO:0007229 | integrin-mediated signaling pathway(GO:0007229) |
0.0 | 0.2 | GO:0016236 | macroautophagy(GO:0016236) |
0.0 | 0.4 | GO:0005978 | glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 4.6 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
0.3 | 1.3 | GO:0033270 | paranode region of axon(GO:0033270) |
0.2 | 0.5 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
0.2 | 1.5 | GO:0031616 | spindle pole centrosome(GO:0031616) |
0.2 | 5.3 | GO:0005844 | polysome(GO:0005844) |
0.1 | 1.1 | GO:0014704 | intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291) |
0.1 | 0.4 | GO:0071065 | alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065) |
0.1 | 0.9 | GO:0016012 | sarcoglycan complex(GO:0016012) |
0.1 | 1.5 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
0.1 | 4.6 | GO:0030018 | Z disc(GO:0030018) |
0.1 | 0.3 | GO:0005687 | U4 snRNP(GO:0005687) |
0.1 | 0.2 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
0.1 | 0.2 | GO:0071546 | pi-body(GO:0071546) |
0.1 | 0.5 | GO:0051233 | spindle midzone(GO:0051233) |
0.1 | 0.2 | GO:0031262 | Ndc80 complex(GO:0031262) |
0.1 | 0.9 | GO:0032059 | bleb(GO:0032059) |
0.1 | 1.2 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
0.1 | 0.2 | GO:0043512 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
0.1 | 0.7 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
0.1 | 1.0 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
0.1 | 0.2 | GO:0031501 | mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185) |
0.1 | 0.4 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
0.1 | 0.8 | GO:0098647 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
0.1 | 0.1 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
0.1 | 0.3 | GO:0030118 | clathrin coat(GO:0030118) clathrin adaptor complex(GO:0030131) |
0.1 | 0.4 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
0.1 | 1.4 | GO:0005801 | cis-Golgi network(GO:0005801) |
0.1 | 0.2 | GO:0016942 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) |
0.1 | 0.3 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
0.0 | 0.1 | GO:0032302 | MutSbeta complex(GO:0032302) |
0.0 | 0.1 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
0.0 | 2.2 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
0.0 | 0.7 | GO:0030127 | COPII vesicle coat(GO:0030127) |
0.0 | 0.2 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
0.0 | 0.4 | GO:0030663 | COPI-coated vesicle membrane(GO:0030663) |
0.0 | 0.1 | GO:0000788 | nuclear nucleosome(GO:0000788) |
0.0 | 0.3 | GO:0005851 | eukaryotic translation initiation factor 2B complex(GO:0005851) |
0.0 | 1.1 | GO:0005859 | muscle myosin complex(GO:0005859) |
0.0 | 0.1 | GO:0036452 | ESCRT III complex(GO:0000815) ESCRT complex(GO:0036452) |
0.0 | 0.1 | GO:0001940 | male pronucleus(GO:0001940) |
0.0 | 0.7 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
0.0 | 0.1 | GO:0005873 | plus-end kinesin complex(GO:0005873) |
0.0 | 0.1 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
0.0 | 1.0 | GO:0005811 | lipid particle(GO:0005811) |
0.0 | 0.1 | GO:0019008 | molybdopterin synthase complex(GO:0019008) |
0.0 | 1.9 | GO:0043679 | axon terminus(GO:0043679) |
0.0 | 0.2 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
0.0 | 0.2 | GO:0070552 | BRISC complex(GO:0070552) |
0.0 | 0.2 | GO:0032311 | angiogenin-PRI complex(GO:0032311) |
0.0 | 0.3 | GO:0034464 | BBSome(GO:0034464) |
0.0 | 0.6 | GO:0031252 | cell leading edge(GO:0031252) |
0.0 | 0.4 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
0.0 | 0.3 | GO:0005858 | axonemal dynein complex(GO:0005858) axoneme part(GO:0044447) |
0.0 | 2.4 | GO:0005604 | basement membrane(GO:0005604) |
0.0 | 0.4 | GO:0071203 | WASH complex(GO:0071203) |
0.0 | 0.9 | GO:0005776 | autophagosome(GO:0005776) |
0.0 | 0.1 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664) beta-catenin-TCF complex(GO:1990907) |
0.0 | 0.6 | GO:0000795 | synaptonemal complex(GO:0000795) |
0.0 | 0.3 | GO:0016585 | obsolete chromatin remodeling complex(GO:0016585) |
0.0 | 0.5 | GO:0070822 | Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822) |
0.0 | 0.2 | GO:0005869 | dynactin complex(GO:0005869) |
0.0 | 0.4 | GO:0043198 | dendritic shaft(GO:0043198) |
0.0 | 8.3 | GO:0005667 | transcription factor complex(GO:0005667) |
0.0 | 1.7 | GO:0016459 | myosin complex(GO:0016459) |
0.0 | 0.5 | GO:0030132 | clathrin coat of coated pit(GO:0030132) |
0.0 | 1.4 | GO:0031228 | intrinsic component of Golgi membrane(GO:0031228) |
0.0 | 0.7 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
0.0 | 0.2 | GO:0060199 | clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203) |
0.0 | 0.1 | GO:0032133 | chromosome passenger complex(GO:0032133) |
0.0 | 1.1 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.0 | 0.2 | GO:0000445 | transcription export complex(GO:0000346) THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
0.0 | 0.6 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
0.0 | 1.9 | GO:0030426 | growth cone(GO:0030426) |
0.0 | 0.1 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
0.0 | 1.9 | GO:0043292 | contractile fiber(GO:0043292) |
0.0 | 0.1 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.0 | 0.1 | GO:0016471 | vacuolar proton-transporting V-type ATPase complex(GO:0016471) |
0.0 | 0.2 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
0.0 | 1.6 | GO:0060205 | cytoplasmic membrane-bounded vesicle lumen(GO:0060205) |
0.0 | 0.2 | GO:0005765 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
0.0 | 0.7 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
0.0 | 0.1 | GO:0070852 | cell body fiber(GO:0070852) |
0.0 | 0.0 | GO:0000785 | chromatin(GO:0000785) |
0.0 | 0.2 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.0 | 0.2 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
0.0 | 0.2 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.0 | 0.1 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
0.0 | 0.2 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
0.0 | 0.4 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
0.0 | 0.2 | GO:0005775 | vacuolar lumen(GO:0005775) |
0.0 | 0.1 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
0.0 | 0.1 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
0.0 | 0.4 | GO:0042612 | MHC class I protein complex(GO:0042612) |
0.0 | 0.2 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.0 | 0.6 | GO:0098636 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
0.0 | 1.7 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
0.0 | 0.2 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
0.0 | 0.0 | GO:0031143 | pseudopodium(GO:0031143) |
0.0 | 0.7 | GO:0005626 | obsolete insoluble fraction(GO:0005626) |
0.0 | 0.0 | GO:0010370 | perinucleolar chromocenter(GO:0010370) |
0.0 | 0.6 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.0 | 0.7 | GO:0005905 | clathrin-coated pit(GO:0005905) |
0.0 | 0.3 | GO:0019898 | extrinsic component of membrane(GO:0019898) |
0.0 | 0.3 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
0.0 | 0.1 | GO:0030686 | 90S preribosome(GO:0030686) |
0.0 | 0.1 | GO:0032589 | neuron projection membrane(GO:0032589) |
0.0 | 0.6 | GO:0031901 | early endosome membrane(GO:0031901) |
0.0 | 1.0 | GO:0000790 | nuclear chromatin(GO:0000790) |
0.0 | 0.0 | GO:0042629 | mast cell granule(GO:0042629) |
0.0 | 0.3 | GO:0005798 | Golgi-associated vesicle(GO:0005798) |
0.0 | 0.0 | GO:0035145 | exon-exon junction complex(GO:0035145) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.5 | 5.9 | GO:0008112 | nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760) |
0.8 | 9.8 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093) |
0.7 | 2.2 | GO:0050062 | long-chain-fatty-acyl-CoA reductase activity(GO:0050062) |
0.7 | 2.0 | GO:0032089 | NACHT domain binding(GO:0032089) |
0.3 | 1.4 | GO:0019834 | phospholipase A2 inhibitor activity(GO:0019834) |
0.3 | 1.0 | GO:0004781 | adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781) |
0.3 | 0.9 | GO:0004139 | deoxyribose-phosphate aldolase activity(GO:0004139) |
0.3 | 1.4 | GO:0004882 | androgen receptor activity(GO:0004882) |
0.3 | 1.4 | GO:0042043 | neurexin family protein binding(GO:0042043) |
0.2 | 0.7 | GO:0002114 | interleukin-33 receptor activity(GO:0002114) |
0.2 | 0.7 | GO:0031755 | endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755) |
0.2 | 6.7 | GO:0019843 | rRNA binding(GO:0019843) |
0.2 | 0.8 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
0.2 | 0.9 | GO:0016403 | dimethylargininase activity(GO:0016403) |
0.2 | 0.9 | GO:0016933 | extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934) |
0.2 | 0.5 | GO:0004948 | calcitonin receptor activity(GO:0004948) |
0.2 | 1.5 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
0.2 | 0.8 | GO:0060961 | phospholipase D inhibitor activity(GO:0060961) |
0.1 | 0.6 | GO:0004346 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
0.1 | 2.2 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.1 | 1.0 | GO:0016717 | oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717) |
0.1 | 0.9 | GO:0047894 | flavonol 3-sulfotransferase activity(GO:0047894) |
0.1 | 1.5 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
0.1 | 0.7 | GO:0042577 | lipid phosphatase activity(GO:0042577) |
0.1 | 0.6 | GO:0004064 | arylesterase activity(GO:0004064) |
0.1 | 0.5 | GO:0035184 | histone threonine kinase activity(GO:0035184) |
0.1 | 0.3 | GO:0030377 | urokinase plasminogen activator receptor activity(GO:0030377) |
0.1 | 0.9 | GO:0031685 | adenosine receptor binding(GO:0031685) |
0.1 | 0.4 | GO:0004321 | fatty-acyl-CoA synthase activity(GO:0004321) |
0.1 | 0.3 | GO:0004939 | beta-adrenergic receptor activity(GO:0004939) |
0.1 | 0.2 | GO:0048184 | obsolete follistatin binding(GO:0048184) |
0.1 | 1.0 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
0.1 | 0.6 | GO:0004800 | thyroxine 5'-deiodinase activity(GO:0004800) |
0.1 | 0.8 | GO:0004062 | aryl sulfotransferase activity(GO:0004062) |
0.1 | 0.6 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
0.1 | 3.7 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
0.1 | 0.4 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
0.1 | 0.9 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
0.1 | 0.4 | GO:0004386 | helicase activity(GO:0004386) |
0.1 | 1.0 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
0.1 | 0.8 | GO:0030172 | troponin C binding(GO:0030172) |
0.1 | 0.3 | GO:0004504 | peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598) |
0.1 | 1.2 | GO:0043274 | phospholipase binding(GO:0043274) |
0.1 | 0.2 | GO:0016362 | activin receptor activity, type II(GO:0016362) |
0.1 | 0.8 | GO:0031419 | cobalamin binding(GO:0031419) |
0.1 | 0.4 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
0.1 | 0.8 | GO:0004745 | retinol dehydrogenase activity(GO:0004745) |
0.1 | 2.2 | GO:0005024 | transforming growth factor beta-activated receptor activity(GO:0005024) |
0.1 | 0.4 | GO:0031404 | chloride ion binding(GO:0031404) |
0.1 | 0.4 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
0.1 | 0.5 | GO:0045502 | dynein binding(GO:0045502) |
0.1 | 0.2 | GO:0004307 | ethanolaminephosphotransferase activity(GO:0004307) |
0.1 | 0.2 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
0.1 | 0.2 | GO:0070996 | type 1 melanocortin receptor binding(GO:0070996) |
0.1 | 0.2 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
0.1 | 0.4 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
0.1 | 0.5 | GO:0033130 | acetylcholine receptor binding(GO:0033130) |
0.1 | 0.5 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
0.1 | 0.8 | GO:0003706 | obsolete ligand-regulated transcription factor activity(GO:0003706) |
0.1 | 0.5 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
0.1 | 0.3 | GO:0003960 | NADPH:quinone reductase activity(GO:0003960) |
0.1 | 0.2 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
0.1 | 0.2 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
0.1 | 0.2 | GO:0004937 | alpha1-adrenergic receptor activity(GO:0004937) |
0.1 | 0.4 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
0.1 | 0.5 | GO:0042153 | obsolete RPTP-like protein binding(GO:0042153) alpha-catenin binding(GO:0045294) |
0.1 | 1.5 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.1 | 0.5 | GO:0019237 | centromeric DNA binding(GO:0019237) |
0.1 | 0.6 | GO:0005243 | gap junction channel activity(GO:0005243) |
0.1 | 5.4 | GO:0005178 | integrin binding(GO:0005178) |
0.1 | 0.3 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
0.1 | 1.6 | GO:0017022 | myosin binding(GO:0017022) |
0.1 | 0.5 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.1 | 0.6 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
0.0 | 0.3 | GO:0003920 | GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657) |
0.0 | 1.5 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.0 | 0.1 | GO:0008267 | poly-glutamine tract binding(GO:0008267) |
0.0 | 0.2 | GO:0016997 | exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) |
0.0 | 1.1 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.0 | 0.1 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
0.0 | 0.6 | GO:0001619 | obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619) |
0.0 | 0.3 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
0.0 | 0.1 | GO:0015439 | heme-transporting ATPase activity(GO:0015439) |
0.0 | 0.1 | GO:0004960 | thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961) |
0.0 | 0.7 | GO:0005521 | lamin binding(GO:0005521) |
0.0 | 0.2 | GO:0051434 | BH3 domain binding(GO:0051434) |
0.0 | 0.2 | GO:0047631 | ADP-ribose diphosphatase activity(GO:0047631) |
0.0 | 0.1 | GO:0070644 | vitamin D response element binding(GO:0070644) |
0.0 | 0.3 | GO:0016778 | diphosphotransferase activity(GO:0016778) |
0.0 | 0.1 | GO:0004962 | endothelin receptor activity(GO:0004962) |
0.0 | 0.3 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
0.0 | 1.0 | GO:0008373 | sialyltransferase activity(GO:0008373) |
0.0 | 0.6 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
0.0 | 0.2 | GO:0046592 | polyamine oxidase activity(GO:0046592) |
0.0 | 1.6 | GO:0005518 | collagen binding(GO:0005518) |
0.0 | 0.6 | GO:0051787 | misfolded protein binding(GO:0051787) |
0.0 | 0.1 | GO:0030611 | arsenate reductase activity(GO:0030611) |
0.0 | 0.9 | GO:0008376 | acetylgalactosaminyltransferase activity(GO:0008376) |
0.0 | 0.4 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
0.0 | 0.1 | GO:0016842 | amidine-lyase activity(GO:0016842) |
0.0 | 0.1 | GO:0008466 | glycogenin glucosyltransferase activity(GO:0008466) |
0.0 | 0.0 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
0.0 | 0.1 | GO:0001517 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) |
0.0 | 0.2 | GO:0031994 | insulin-like growth factor I binding(GO:0031994) |
0.0 | 0.1 | GO:0034875 | oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875) |
0.0 | 1.0 | GO:0005504 | fatty acid binding(GO:0005504) |
0.0 | 0.6 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
0.0 | 0.2 | GO:0004017 | adenylate kinase activity(GO:0004017) |
0.0 | 0.2 | GO:0042826 | histone deacetylase binding(GO:0042826) |
0.0 | 0.1 | GO:0003996 | acyl-CoA ligase activity(GO:0003996) |
0.0 | 0.1 | GO:0008174 | mRNA methyltransferase activity(GO:0008174) |
0.0 | 0.4 | GO:0005123 | death receptor binding(GO:0005123) |
0.0 | 0.2 | GO:0004784 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
0.0 | 0.4 | GO:0008143 | poly(A) binding(GO:0008143) |
0.0 | 0.3 | GO:0008494 | translation activator activity(GO:0008494) |
0.0 | 0.4 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
0.0 | 0.1 | GO:0070643 | vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643) |
0.0 | 0.4 | GO:0030332 | cyclin binding(GO:0030332) |
0.0 | 0.6 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
0.0 | 0.1 | GO:0031711 | angiotensin type I receptor activity(GO:0001596) bradykinin receptor binding(GO:0031711) |
0.0 | 2.2 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.0 | 0.2 | GO:0004835 | tubulin-tyrosine ligase activity(GO:0004835) |
0.0 | 0.1 | GO:0015174 | basic amino acid transmembrane transporter activity(GO:0015174) |
0.0 | 0.1 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
0.0 | 0.6 | GO:0004623 | phospholipase A2 activity(GO:0004623) |
0.0 | 0.1 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.0 | 0.5 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
0.0 | 0.1 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
0.0 | 0.6 | GO:0016646 | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646) |
0.0 | 0.1 | GO:0047617 | acyl-CoA hydrolase activity(GO:0047617) |
0.0 | 0.1 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
0.0 | 1.6 | GO:0004714 | transmembrane receptor protein tyrosine kinase activity(GO:0004714) transmembrane receptor protein kinase activity(GO:0019199) |
0.0 | 0.1 | GO:0019956 | chemokine binding(GO:0019956) |
0.0 | 0.2 | GO:0044548 | S100 protein binding(GO:0044548) |
0.0 | 1.5 | GO:0008307 | structural constituent of muscle(GO:0008307) |
0.0 | 1.4 | GO:0003743 | translation initiation factor activity(GO:0003743) |
0.0 | 0.1 | GO:0047045 | testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045) |
0.0 | 0.1 | GO:0030197 | extracellular matrix constituent, lubricant activity(GO:0030197) |
0.0 | 0.1 | GO:0004126 | cytidine deaminase activity(GO:0004126) |
0.0 | 0.4 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
0.0 | 0.3 | GO:0048365 | Rac GTPase binding(GO:0048365) |
0.0 | 0.0 | GO:0046403 | polynucleotide 3'-phosphatase activity(GO:0046403) |
0.0 | 3.9 | GO:0008022 | protein C-terminus binding(GO:0008022) |
0.0 | 0.1 | GO:0004618 | phosphoglycerate kinase activity(GO:0004618) |
0.0 | 0.1 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
0.0 | 0.4 | GO:0016628 | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628) |
0.0 | 0.2 | GO:0016853 | isomerase activity(GO:0016853) |
0.0 | 0.1 | GO:0042731 | PH domain binding(GO:0042731) |
0.0 | 0.1 | GO:0004738 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739) |
0.0 | 0.4 | GO:0051219 | phosphoprotein binding(GO:0051219) |
0.0 | 0.4 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.0 | 0.1 | GO:0016206 | catechol O-methyltransferase activity(GO:0016206) |
0.0 | 0.9 | GO:0016564 | obsolete transcription repressor activity(GO:0016564) |
0.0 | 0.2 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
0.0 | 0.2 | GO:0070888 | E-box binding(GO:0070888) |
0.0 | 0.2 | GO:0050786 | RAGE receptor binding(GO:0050786) |
0.0 | 0.2 | GO:0050839 | cell adhesion molecule binding(GO:0050839) |
0.0 | 0.1 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
0.0 | 0.1 | GO:0004911 | interleukin-2 receptor activity(GO:0004911) |
0.0 | 0.3 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
0.0 | 0.2 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
0.0 | 0.2 | GO:0016641 | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641) |
0.0 | 0.1 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
0.0 | 0.6 | GO:0008009 | chemokine activity(GO:0008009) |
0.0 | 0.1 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939) |
0.0 | 0.2 | GO:0005391 | sodium:potassium-exchanging ATPase activity(GO:0005391) |
0.0 | 0.1 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
0.0 | 0.2 | GO:0008536 | Ran GTPase binding(GO:0008536) |
0.0 | 0.5 | GO:0050681 | androgen receptor binding(GO:0050681) |
0.0 | 0.0 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |
0.0 | 0.2 | GO:0015929 | hexosaminidase activity(GO:0015929) |
0.0 | 0.7 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
0.0 | 0.0 | GO:0004180 | carboxypeptidase activity(GO:0004180) |
0.0 | 0.6 | GO:0030165 | PDZ domain binding(GO:0030165) |
0.0 | 0.5 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
0.0 | 0.4 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
0.0 | 0.1 | GO:0004668 | protein-arginine deiminase activity(GO:0004668) |
0.0 | 0.0 | GO:0004531 | deoxyribonuclease II activity(GO:0004531) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 1.2 | SA_FAS_SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
0.0 | 0.5 | SA_CASPASE_CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
0.0 | 0.2 | SA_PROGRAMMED_CELL_DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
0.0 | 0.1 | ST_GAQ_PATHWAY | G alpha q Pathway |
0.0 | 0.7 | SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES | Genes related to the insulin receptor pathway |