Motif ID: CAGUGCA
Z-value: 1.292
Mature miRNA associated with seed CAGUGCA:
| Name | miRBase Accession |
|---|---|
| hsa-miR-148a-3p | MIMAT0000243 |
| hsa-miR-148b-3p | MIMAT0000759 |
| hsa-miR-152-3p | MIMAT0000438 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.0 | GO:0043276 | anoikis(GO:0043276) |
| 0.3 | 0.8 | GO:0060279 | regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279) |
| 0.2 | 0.7 | GO:0010757 | chronological cell aging(GO:0001300) arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540) negative regulation of plasminogen activation(GO:0010757) negative regulation of cell adhesion mediated by integrin(GO:0033629) |
| 0.2 | 0.6 | GO:0032927 | positive regulation of activin receptor signaling pathway(GO:0032927) |
| 0.2 | 1.3 | GO:0033630 | positive regulation of cell adhesion mediated by integrin(GO:0033630) |
| 0.1 | 0.4 | GO:0007206 | phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) |
| 0.1 | 1.3 | GO:0008354 | germ cell migration(GO:0008354) |
| 0.1 | 1.3 | GO:0071692 | sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116) |
| 0.1 | 0.1 | GO:0051088 | PMA-inducible membrane protein ectodomain proteolysis(GO:0051088) |
| 0.1 | 0.7 | GO:0014012 | peripheral nervous system axon regeneration(GO:0014012) |
| 0.1 | 0.3 | GO:0010273 | regulation of oxidative phosphorylation(GO:0002082) detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169) |
| 0.1 | 0.3 | GO:0015959 | diadenosine polyphosphate metabolic process(GO:0015959) |
| 0.1 | 0.4 | GO:0006408 | snRNA export from nucleus(GO:0006408) snRNA transport(GO:0051030) |
| 0.1 | 0.3 | GO:0070544 | histone H3-K36 demethylation(GO:0070544) |
| 0.1 | 0.9 | GO:0040037 | negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037) |
| 0.1 | 0.3 | GO:0032914 | positive regulation of transforming growth factor beta1 production(GO:0032914) |
| 0.1 | 1.0 | GO:0060123 | regulation of growth hormone secretion(GO:0060123) |
| 0.1 | 0.5 | GO:0042117 | monocyte activation(GO:0042117) |
| 0.1 | 1.2 | GO:0051602 | response to electrical stimulus(GO:0051602) |
| 0.1 | 0.2 | GO:0006679 | glucosylceramide biosynthetic process(GO:0006679) |
| 0.1 | 0.5 | GO:0060272 | embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498) |
| 0.1 | 1.3 | GO:0014037 | Schwann cell differentiation(GO:0014037) |
| 0.1 | 1.0 | GO:0071044 | histone mRNA catabolic process(GO:0071044) |
| 0.1 | 0.3 | GO:0070669 | response to interleukin-2(GO:0070669) |
| 0.1 | 0.2 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
| 0.1 | 0.5 | GO:0035162 | embryonic hemopoiesis(GO:0035162) |
| 0.0 | 0.1 | GO:0035234 | ectopic germ cell programmed cell death(GO:0035234) |
| 0.0 | 0.5 | GO:0001706 | endoderm formation(GO:0001706) |
| 0.0 | 0.4 | GO:0045880 | positive regulation of smoothened signaling pathway(GO:0045880) |
| 0.0 | 0.1 | GO:0001757 | somite specification(GO:0001757) |
| 0.0 | 0.4 | GO:0043545 | Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189) |
| 0.0 | 0.1 | GO:0010834 | obsolete telomere maintenance via telomere shortening(GO:0010834) |
| 0.0 | 0.2 | GO:0071318 | cellular response to ATP(GO:0071318) |
| 0.0 | 0.2 | GO:0010508 | positive regulation of autophagy(GO:0010508) |
| 0.0 | 0.2 | GO:0014819 | regulation of skeletal muscle contraction(GO:0014819) |
| 0.0 | 0.3 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.0 | 0.3 | GO:0015886 | heme transport(GO:0015886) |
| 0.0 | 0.7 | GO:0014003 | oligodendrocyte development(GO:0014003) |
| 0.0 | 0.1 | GO:0002361 | CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361) |
| 0.0 | 0.1 | GO:0001661 | conditioned taste aversion(GO:0001661) |
| 0.0 | 0.2 | GO:0032007 | negative regulation of TOR signaling(GO:0032007) |
| 0.0 | 0.1 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
| 0.0 | 0.2 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
| 0.0 | 0.3 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.0 | 0.2 | GO:0006621 | protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437) |
| 0.0 | 0.4 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
| 0.0 | 0.1 | GO:0045662 | negative regulation of myoblast differentiation(GO:0045662) |
| 0.0 | 0.6 | GO:0032570 | response to progesterone(GO:0032570) |
| 0.0 | 0.1 | GO:0007144 | female meiosis I(GO:0007144) |
| 0.0 | 0.1 | GO:0051497 | negative regulation of stress fiber assembly(GO:0051497) |
| 0.0 | 0.6 | GO:0046847 | filopodium assembly(GO:0046847) |
| 0.0 | 0.5 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
| 0.0 | 0.3 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
| 0.0 | 1.4 | GO:0009408 | response to heat(GO:0009408) |
| 0.0 | 0.2 | GO:0006107 | oxaloacetate metabolic process(GO:0006107) |
| 0.0 | 0.1 | GO:0016576 | histone dephosphorylation(GO:0016576) |
| 0.0 | 0.1 | GO:0048388 | endosomal lumen acidification(GO:0048388) |
| 0.0 | 0.3 | GO:0045668 | negative regulation of osteoblast differentiation(GO:0045668) |
| 0.0 | 0.4 | GO:0019835 | cytolysis(GO:0019835) |
| 0.0 | 0.3 | GO:0045604 | regulation of epidermal cell differentiation(GO:0045604) |
| 0.0 | 0.1 | GO:0014850 | response to muscle activity(GO:0014850) |
| 0.0 | 0.3 | GO:0035329 | hippo signaling(GO:0035329) |
| 0.0 | 0.1 | GO:0010891 | negative regulation of sequestering of triglyceride(GO:0010891) positive regulation of triglyceride catabolic process(GO:0010898) |
| 0.0 | 0.0 | GO:0016082 | synaptic vesicle priming(GO:0016082) |
| 0.0 | 0.1 | GO:0046642 | negative regulation of alpha-beta T cell proliferation(GO:0046642) |
| 0.0 | 0.0 | GO:0042339 | keratan sulfate metabolic process(GO:0042339) |
| 0.0 | 0.1 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 0.0 | 0.1 | GO:0051180 | vitamin transport(GO:0051180) |
| 0.0 | 0.0 | GO:0008356 | asymmetric cell division(GO:0008356) |
| 0.0 | 0.1 | GO:0060762 | regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) |
| 0.0 | 0.8 | GO:0007588 | excretion(GO:0007588) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.4 | GO:0044298 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
| 0.1 | 1.4 | GO:0001527 | microfibril(GO:0001527) |
| 0.1 | 0.9 | GO:0016442 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
| 0.1 | 0.3 | GO:0071256 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 0.1 | 0.1 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.0 | 0.5 | GO:0005678 | obsolete chromatin assembly complex(GO:0005678) |
| 0.0 | 0.8 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.0 | 0.5 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.0 | 1.3 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.0 | 0.3 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.0 | 0.2 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.0 | 0.2 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.0 | 0.4 | GO:0098647 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.0 | 0.1 | GO:0000153 | cytoplasmic ubiquitin ligase complex(GO:0000153) |
| 0.0 | 0.7 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 1.4 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 0.6 | GO:0005844 | polysome(GO:0005844) |
| 0.0 | 0.2 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.0 | 0.1 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.0 | 0.4 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.0 | 0.4 | GO:0043034 | costamere(GO:0043034) |
| 0.0 | 0.3 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.0 | 0.1 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.0 | 0.1 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453) |
| 0.0 | 0.1 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 0.0 | 0.6 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 0.3 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.0 | 0.1 | GO:0005587 | collagen type IV trimer(GO:0005587) |
| 0.0 | 0.6 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 0.2 | GO:0005922 | connexon complex(GO:0005922) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.4 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.2 | 1.3 | GO:0042577 | lipid phosphatase activity(GO:0042577) |
| 0.2 | 0.6 | GO:0016362 | activin receptor activity, type II(GO:0016362) |
| 0.1 | 0.4 | GO:0030151 | molybdenum ion binding(GO:0030151) |
| 0.1 | 0.5 | GO:0005157 | macrophage colony-stimulating factor receptor binding(GO:0005157) |
| 0.1 | 0.5 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
| 0.1 | 0.3 | GO:0016531 | copper chaperone activity(GO:0016531) |
| 0.1 | 1.3 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.1 | 1.4 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
| 0.1 | 0.5 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
| 0.1 | 0.3 | GO:0008486 | diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) |
| 0.1 | 1.0 | GO:0016896 | exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896) |
| 0.1 | 0.9 | GO:0004065 | arylsulfatase activity(GO:0004065) |
| 0.1 | 0.2 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 0.0 | 0.3 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.0 | 0.3 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
| 0.0 | 0.5 | GO:0005114 | type II transforming growth factor beta receptor binding(GO:0005114) |
| 0.0 | 0.2 | GO:0005294 | neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294) |
| 0.0 | 0.4 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.0 | 0.3 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.0 | 0.2 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 0.0 | 0.2 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.0 | 0.3 | GO:0015232 | heme transporter activity(GO:0015232) |
| 0.0 | 0.3 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.0 | 2.5 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.1 | GO:0050613 | delta14-sterol reductase activity(GO:0050613) |
| 0.0 | 0.3 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093) |
| 0.0 | 0.7 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.0 | 0.7 | GO:0097472 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472) |
| 0.0 | 0.1 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
| 0.0 | 0.1 | GO:0046934 | obsolete inositol or phosphatidylinositol kinase activity(GO:0004428) phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813) |
| 0.0 | 0.2 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.0 | 0.1 | GO:0003691 | double-stranded telomeric DNA binding(GO:0003691) |
| 0.0 | 0.6 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.0 | 0.3 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.0 | 0.1 | GO:0070700 | BMP receptor binding(GO:0070700) |
| 0.0 | 0.5 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.0 | 0.1 | GO:0030546 | receptor activator activity(GO:0030546) |
| 0.0 | 0.2 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
| 0.0 | 0.2 | GO:0003756 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
| 0.0 | 0.1 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.0 | 1.7 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.0 | 1.1 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 1.0 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 0.1 | GO:0046625 | sphingolipid binding(GO:0046625) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.9 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.0 | 0.8 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.0 | 0.6 | SIG_CD40PATHWAYMAP | Genes related to CD40 signaling |
