Motif ID: CCCUGAG
Z-value: 2.299
Mature miRNA associated with seed CCCUGAG:
| Name | miRBase Accession |
|---|---|
| hsa-miR-125a-5p | MIMAT0000443 |
| hsa-miR-125b-5p | MIMAT0000423 |
| hsa-miR-4319 | MIMAT0016870 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 3.3 | GO:0034139 | regulation of toll-like receptor 2 signaling pathway(GO:0034135) regulation of toll-like receptor 3 signaling pathway(GO:0034139) negative regulation of epithelial cell apoptotic process(GO:1904036) negative regulation of endothelial cell apoptotic process(GO:2000352) |
| 0.9 | 2.6 | GO:0015920 | lipopolysaccharide transport(GO:0015920) |
| 0.6 | 1.1 | GO:2000114 | regulation of establishment of cell polarity(GO:2000114) |
| 0.5 | 1.9 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
| 0.5 | 1.4 | GO:0042097 | interleukin-4 biosynthetic process(GO:0042097) positive regulation of interleukin-10 biosynthetic process(GO:0045082) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404) |
| 0.5 | 1.4 | GO:0070544 | histone H3-K36 demethylation(GO:0070544) |
| 0.4 | 2.2 | GO:0048845 | venous blood vessel morphogenesis(GO:0048845) |
| 0.3 | 1.3 | GO:0046671 | regulation of nitrogen utilization(GO:0006808) positive regulation of neuron maturation(GO:0014042) nitrogen utilization(GO:0019740) cochlear nucleus development(GO:0021747) negative regulation of cellular pH reduction(GO:0032848) glial cell apoptotic process(GO:0034349) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671) positive regulation of cell maturation(GO:1903431) |
| 0.3 | 2.2 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
| 0.3 | 1.2 | GO:0048935 | peripheral nervous system neuron development(GO:0048935) |
| 0.3 | 1.1 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
| 0.2 | 1.5 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.2 | 1.4 | GO:0060397 | JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397) |
| 0.2 | 0.6 | GO:0045719 | negative regulation of glycogen biosynthetic process(GO:0045719) |
| 0.2 | 0.6 | GO:0042369 | vitamin D catabolic process(GO:0042369) |
| 0.2 | 0.9 | GO:0018106 | peptidyl-histidine phosphorylation(GO:0018106) |
| 0.2 | 1.7 | GO:0046835 | carbohydrate phosphorylation(GO:0046835) |
| 0.2 | 1.1 | GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552) |
| 0.2 | 0.7 | GO:0048642 | negative regulation of skeletal muscle tissue development(GO:0048642) |
| 0.2 | 0.7 | GO:0051124 | synaptic growth at neuromuscular junction(GO:0051124) |
| 0.2 | 0.5 | GO:0010248 | establishment or maintenance of transmembrane electrochemical gradient(GO:0010248) post-embryonic camera-type eye development(GO:0031077) |
| 0.2 | 2.4 | GO:0009113 | purine nucleobase biosynthetic process(GO:0009113) |
| 0.2 | 0.5 | GO:0060896 | neural plate anterior/posterior regionalization(GO:0021999) neural plate pattern specification(GO:0060896) neural plate regionalization(GO:0060897) |
| 0.1 | 1.4 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.1 | 0.4 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.1 | 0.9 | GO:0042984 | amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984) |
| 0.1 | 0.8 | GO:0019852 | L-ascorbic acid metabolic process(GO:0019852) |
| 0.1 | 2.3 | GO:0014037 | Schwann cell differentiation(GO:0014037) |
| 0.1 | 1.4 | GO:0008272 | sulfate transport(GO:0008272) |
| 0.1 | 0.3 | GO:2000078 | epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287) regulation of type B pancreatic cell development(GO:2000074) positive regulation of type B pancreatic cell development(GO:2000078) |
| 0.1 | 1.5 | GO:0051319 | mitotic G2 phase(GO:0000085) G2 phase(GO:0051319) |
| 0.1 | 0.5 | GO:0032933 | SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501) |
| 0.1 | 0.3 | GO:0006655 | phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471) |
| 0.1 | 0.8 | GO:0000183 | chromatin silencing at rDNA(GO:0000183) |
| 0.1 | 0.5 | GO:0032916 | transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916) |
| 0.1 | 0.2 | GO:0060340 | positive regulation of type I interferon-mediated signaling pathway(GO:0060340) cellular response to exogenous dsRNA(GO:0071360) |
| 0.1 | 0.5 | GO:0050685 | positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313) |
| 0.1 | 0.2 | GO:0090009 | primitive streak formation(GO:0090009) |
| 0.1 | 0.4 | GO:0030578 | nuclear body organization(GO:0030575) PML body organization(GO:0030578) |
| 0.1 | 0.8 | GO:0006975 | DNA damage induced protein phosphorylation(GO:0006975) |
| 0.1 | 0.9 | GO:0048617 | embryonic foregut morphogenesis(GO:0048617) |
| 0.1 | 0.4 | GO:0046952 | ketone body catabolic process(GO:0046952) |
| 0.1 | 0.3 | GO:0071364 | cellular response to epidermal growth factor stimulus(GO:0071364) |
| 0.1 | 0.4 | GO:0009450 | gamma-aminobutyric acid catabolic process(GO:0009450) |
| 0.1 | 0.2 | GO:0010881 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion(GO:0010881) |
| 0.1 | 0.5 | GO:0001554 | luteolysis(GO:0001554) |
| 0.1 | 0.7 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.1 | 0.5 | GO:0015904 | tetracycline transport(GO:0015904) |
| 0.1 | 1.1 | GO:0050930 | induction of positive chemotaxis(GO:0050930) |
| 0.1 | 0.2 | GO:0010586 | miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587) |
| 0.1 | 0.6 | GO:0044341 | sodium-dependent phosphate transport(GO:0044341) |
| 0.1 | 1.1 | GO:0001893 | maternal placenta development(GO:0001893) |
| 0.1 | 0.3 | GO:0048227 | plasma membrane to endosome transport(GO:0048227) |
| 0.1 | 1.2 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.1 | 0.2 | GO:0050928 | negative regulation of positive chemotaxis(GO:0050928) |
| 0.1 | 0.3 | GO:0090103 | outflow tract septum morphogenesis(GO:0003148) cochlea morphogenesis(GO:0090103) |
| 0.1 | 0.5 | GO:0034379 | very-low-density lipoprotein particle assembly(GO:0034379) |
| 0.1 | 0.2 | GO:0072106 | regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107) |
| 0.0 | 0.3 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
| 0.0 | 0.5 | GO:0034260 | negative regulation of GTPase activity(GO:0034260) |
| 0.0 | 0.4 | GO:0051973 | positive regulation of telomerase activity(GO:0051973) |
| 0.0 | 1.9 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
| 0.0 | 0.6 | GO:0043097 | pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097) |
| 0.0 | 0.4 | GO:0043306 | positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306) |
| 0.0 | 0.1 | GO:0051365 | cellular response to potassium ion starvation(GO:0051365) |
| 0.0 | 0.3 | GO:0090400 | stress-induced premature senescence(GO:0090400) |
| 0.0 | 0.2 | GO:0018125 | peptidyl-cysteine methylation(GO:0018125) |
| 0.0 | 1.6 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 0.0 | 0.6 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
| 0.0 | 3.7 | GO:0034339 | obsolete regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor(GO:0034339) |
| 0.0 | 1.6 | GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154) |
| 0.0 | 0.1 | GO:0032223 | negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212) neurotransmitter receptor metabolic process(GO:0045213) |
| 0.0 | 0.7 | GO:0030511 | positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846) |
| 0.0 | 0.2 | GO:0043923 | positive regulation by host of viral transcription(GO:0043923) |
| 0.0 | 0.1 | GO:0045896 | regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897) |
| 0.0 | 1.0 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
| 0.0 | 0.5 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
| 0.0 | 0.1 | GO:0060023 | soft palate development(GO:0060023) |
| 0.0 | 4.2 | GO:0006487 | protein N-linked glycosylation(GO:0006487) |
| 0.0 | 0.5 | GO:0002076 | osteoblast development(GO:0002076) |
| 0.0 | 0.2 | GO:0042518 | negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518) |
| 0.0 | 0.1 | GO:0008053 | mitochondrial fusion(GO:0008053) |
| 0.0 | 0.2 | GO:0007185 | transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185) |
| 0.0 | 0.2 | GO:0035020 | regulation of Rac protein signal transduction(GO:0035020) |
| 0.0 | 0.3 | GO:0051567 | histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647) |
| 0.0 | 0.8 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
| 0.0 | 0.8 | GO:0071804 | cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805) |
| 0.0 | 0.1 | GO:0010842 | retina layer formation(GO:0010842) |
| 0.0 | 0.1 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 0.0 | 0.4 | GO:0021533 | cell differentiation in hindbrain(GO:0021533) |
| 0.0 | 0.2 | GO:0023041 | neuronal signal transduction(GO:0023041) |
| 0.0 | 0.1 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 0.0 | 0.1 | GO:0060081 | membrane hyperpolarization(GO:0060081) |
| 0.0 | 0.3 | GO:1902603 | carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603) |
| 0.0 | 0.1 | GO:0051582 | auditory behavior(GO:0031223) positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) |
| 0.0 | 0.1 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
| 0.0 | 0.2 | GO:0002467 | germinal center formation(GO:0002467) |
| 0.0 | 0.2 | GO:0046627 | negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077) |
| 0.0 | 0.2 | GO:0002053 | positive regulation of mesenchymal cell proliferation(GO:0002053) |
| 0.0 | 0.5 | GO:0033209 | tumor necrosis factor-mediated signaling pathway(GO:0033209) |
| 0.0 | 1.5 | GO:0015718 | monocarboxylic acid transport(GO:0015718) |
| 0.0 | 0.4 | GO:0048146 | positive regulation of fibroblast proliferation(GO:0048146) |
| 0.0 | 0.3 | GO:0007520 | myoblast fusion(GO:0007520) |
| 0.0 | 0.1 | GO:0060291 | long-term synaptic potentiation(GO:0060291) |
| 0.0 | 2.0 | GO:0051028 | mRNA transport(GO:0051028) |
| 0.0 | 0.3 | GO:0034035 | purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) |
| 0.0 | 0.2 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
| 0.0 | 0.2 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.0 | 0.2 | GO:0045725 | positive regulation of glycogen biosynthetic process(GO:0045725) |
| 0.0 | 0.3 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
| 0.0 | 0.1 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.0 | 0.6 | GO:0030177 | positive regulation of Wnt signaling pathway(GO:0030177) |
| 0.0 | 0.9 | GO:0032874 | positive regulation of stress-activated MAPK cascade(GO:0032874) |
| 0.0 | 0.1 | GO:0007405 | neuroblast proliferation(GO:0007405) |
| 0.0 | 1.2 | GO:0043687 | post-translational protein modification(GO:0043687) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 1.4 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.4 | 2.2 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.2 | 0.8 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.2 | 1.9 | GO:0030061 | mitochondrial crista(GO:0030061) |
| 0.2 | 0.8 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.1 | 1.6 | GO:0000808 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 0.1 | 0.5 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
| 0.1 | 0.4 | GO:0032144 | 4-aminobutyrate transaminase complex(GO:0032144) |
| 0.1 | 1.1 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.1 | 0.7 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.1 | 0.5 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.1 | 0.6 | GO:0060199 | clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203) |
| 0.1 | 1.3 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.1 | 2.2 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.1 | 0.8 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
| 0.1 | 0.3 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.1 | 1.3 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 4.0 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.0 | 1.2 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.0 | 0.8 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.0 | 0.2 | GO:0005626 | obsolete insoluble fraction(GO:0005626) |
| 0.0 | 0.2 | GO:0032993 | protein-DNA complex(GO:0032993) |
| 0.0 | 1.3 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.0 | 0.2 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.0 | 0.4 | GO:0070822 | Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822) |
| 0.0 | 0.1 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.0 | 1.0 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 0.3 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.0 | 0.9 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.0 | 0.2 | GO:0001950 | obsolete plasma membrane enriched fraction(GO:0001950) |
| 0.0 | 0.1 | GO:0032444 | activin responsive factor complex(GO:0032444) |
| 0.0 | 2.1 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 0.5 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.0 | 0.3 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
| 0.0 | 0.5 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.0 | 0.1 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 1.0 | GO:0008287 | protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293) |
| 0.0 | 2.1 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.0 | 1.5 | GO:0000790 | nuclear chromatin(GO:0000790) |
| 0.0 | 1.0 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 4.4 | GO:0005813 | centrosome(GO:0005813) |
| 0.0 | 0.4 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.0 | 0.1 | GO:0005851 | eukaryotic translation initiation factor 2B complex(GO:0005851) |
| 0.0 | 0.6 | GO:0030175 | filopodium(GO:0030175) |
| 0.0 | 0.3 | GO:0005844 | polysome(GO:0005844) |
| 0.0 | 0.2 | GO:0042588 | zymogen granule(GO:0042588) |
| 0.0 | 1.1 | GO:0070160 | bicellular tight junction(GO:0005923) occluding junction(GO:0070160) |
| 0.0 | 0.5 | GO:0098636 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
| 0.0 | 0.1 | GO:0032039 | integrator complex(GO:0032039) |
| 0.0 | 1.0 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.0 | 0.1 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 2.9 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
| 0.6 | 2.6 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
| 0.4 | 2.5 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.4 | 1.2 | GO:0050692 | DBD domain binding(GO:0050692) |
| 0.4 | 1.1 | GO:0044325 | ion channel binding(GO:0044325) |
| 0.4 | 1.1 | GO:0004605 | phosphatidate cytidylyltransferase activity(GO:0004605) |
| 0.3 | 1.7 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
| 0.3 | 2.1 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.3 | 1.1 | GO:0016997 | exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) |
| 0.3 | 1.3 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.3 | 0.8 | GO:0008525 | phosphatidylcholine transporter activity(GO:0008525) |
| 0.3 | 0.8 | GO:0008489 | UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489) |
| 0.3 | 0.8 | GO:0008523 | sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) |
| 0.2 | 1.4 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.2 | 1.7 | GO:0004340 | glucokinase activity(GO:0004340) |
| 0.2 | 0.9 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.2 | 2.5 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 0.2 | 1.4 | GO:0008271 | secondary active sulfate transmembrane transporter activity(GO:0008271) |
| 0.2 | 4.9 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.2 | 0.5 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.2 | 1.6 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.2 | 0.5 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
| 0.1 | 0.4 | GO:0042285 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
| 0.1 | 2.3 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.1 | 0.6 | GO:0070576 | vitamin D 24-hydroxylase activity(GO:0070576) |
| 0.1 | 0.4 | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity(GO:0003858) |
| 0.1 | 0.5 | GO:0000247 | C-8 sterol isomerase activity(GO:0000247) |
| 0.1 | 0.6 | GO:0005315 | inorganic phosphate transmembrane transporter activity(GO:0005315) |
| 0.1 | 0.4 | GO:0032145 | 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298) |
| 0.1 | 0.8 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.1 | 0.6 | GO:0004528 | phosphodiesterase I activity(GO:0004528) 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656) |
| 0.1 | 1.1 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.1 | 0.5 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.1 | 0.5 | GO:0015520 | tetracycline:proton antiporter activity(GO:0015520) |
| 0.1 | 0.6 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 0.1 | 1.1 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.1 | 0.3 | GO:0016847 | 1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847) |
| 0.1 | 0.4 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
| 0.1 | 0.3 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
| 0.1 | 0.2 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
| 0.1 | 0.4 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
| 0.1 | 2.4 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
| 0.1 | 0.8 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.1 | 0.2 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 0.1 | 3.0 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.1 | 1.2 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.1 | 0.3 | GO:0015174 | basic amino acid transmembrane transporter activity(GO:0015174) |
| 0.1 | 1.1 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.1 | 0.3 | GO:0048406 | nerve growth factor binding(GO:0048406) |
| 0.0 | 1.4 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.0 | 0.4 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
| 0.0 | 0.7 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.0 | 0.2 | GO:0008599 | protein phosphatase type 1 regulator activity(GO:0008599) |
| 0.0 | 3.2 | GO:0004879 | RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531) |
| 0.0 | 0.1 | GO:0017057 | glucose-6-phosphate dehydrogenase activity(GO:0004345) 6-phosphogluconolactonase activity(GO:0017057) |
| 0.0 | 0.7 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.0 | 0.2 | GO:0050700 | CARD domain binding(GO:0050700) |
| 0.0 | 0.1 | GO:0008431 | vitamin E binding(GO:0008431) |
| 0.0 | 1.5 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
| 0.0 | 0.4 | GO:0043325 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.0 | 0.1 | GO:0004985 | opioid receptor activity(GO:0004985) |
| 0.0 | 0.4 | GO:0047617 | acyl-CoA hydrolase activity(GO:0047617) |
| 0.0 | 0.2 | GO:0008107 | galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127) |
| 0.0 | 0.1 | GO:0003990 | acetylcholinesterase activity(GO:0003990) |
| 0.0 | 0.3 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.0 | 0.5 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) |
| 0.0 | 1.0 | GO:0097472 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472) |
| 0.0 | 0.4 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.0 | 0.1 | GO:0004768 | stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) |
| 0.0 | 0.3 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
| 0.0 | 0.4 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.0 | 0.5 | GO:0003707 | steroid hormone receptor activity(GO:0003707) |
| 0.0 | 0.1 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
| 0.0 | 0.8 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.0 | 0.3 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.0 | 0.1 | GO:0042156 | obsolete zinc-mediated transcriptional activator activity(GO:0042156) |
| 0.0 | 0.7 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.0 | 0.9 | GO:0030145 | manganese ion binding(GO:0030145) |
| 0.0 | 0.3 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.0 | 1.0 | GO:0008080 | N-acetyltransferase activity(GO:0008080) |
| 0.0 | 4.5 | GO:0016563 | obsolete transcription activator activity(GO:0016563) |
| 0.0 | 0.8 | GO:0015297 | antiporter activity(GO:0015297) |
| 0.0 | 0.5 | GO:0004177 | aminopeptidase activity(GO:0004177) |
| 0.0 | 0.2 | GO:1990782 | receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782) |
| 0.0 | 0.2 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.0 | 0.2 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.0 | 1.9 | GO:0003682 | chromatin binding(GO:0003682) |
| 0.0 | 0.1 | GO:0001591 | dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) |
| 0.0 | 0.1 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 0.4 | GO:0003704 | obsolete specific RNA polymerase II transcription factor activity(GO:0003704) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.3 | SA_FAS_SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 0.1 | 1.5 | ST_STAT3_PATHWAY | STAT3 Pathway |
| 0.1 | 3.9 | ST_TUMOR_NECROSIS_FACTOR_PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.1 | 3.0 | SA_B_CELL_RECEPTOR_COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.1 | 3.0 | ST_P38_MAPK_PATHWAY | p38 MAPK Pathway |
| 0.0 | 0.5 | SA_PROGRAMMED_CELL_DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.0 | 0.5 | SA_CASPASE_CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.0 | 0.4 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.0 | 0.5 | ST_JNK_MAPK_PATHWAY | JNK MAPK Pathway |
