Motif ID: CCUUCAU
Z-value: 0.965
Mature miRNA associated with seed CCUUCAU:
Name | miRBase Accession |
---|---|
hsa-miR-205-5p | MIMAT0000266 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.4 | GO:0042271 | susceptibility to natural killer cell mediated cytotoxicity(GO:0042271) |
0.2 | 0.7 | GO:0045198 | establishment of epithelial cell apical/basal polarity(GO:0045198) |
0.2 | 0.5 | GO:0032571 | response to vitamin K(GO:0032571) |
0.1 | 1.2 | GO:0022617 | extracellular matrix disassembly(GO:0022617) |
0.1 | 0.4 | GO:0055005 | optic placode formation involved in camera-type eye formation(GO:0046619) venous blood vessel morphogenesis(GO:0048845) ventricular cardiac myofibril assembly(GO:0055005) regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251) |
0.1 | 0.4 | GO:0002575 | basophil chemotaxis(GO:0002575) |
0.1 | 2.3 | GO:0014037 | Schwann cell differentiation(GO:0014037) |
0.1 | 0.3 | GO:0060596 | mammary placode formation(GO:0060596) |
0.1 | 0.4 | GO:0051387 | negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387) |
0.1 | 0.2 | GO:0035461 | vitamin transmembrane transport(GO:0035461) |
0.1 | 0.5 | GO:0043951 | negative regulation of cAMP-mediated signaling(GO:0043951) |
0.1 | 0.2 | GO:0019521 | aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521) |
0.0 | 0.1 | GO:0035408 | histone H3-T6 phosphorylation(GO:0035408) |
0.0 | 0.1 | GO:0060267 | transformation of host cell by virus(GO:0019087) positive regulation of respiratory burst(GO:0060267) |
0.0 | 0.2 | GO:0046607 | positive regulation of centrosome cycle(GO:0046607) |
0.0 | 0.3 | GO:0032429 | regulation of phospholipase A2 activity(GO:0032429) |
0.0 | 0.2 | GO:0071480 | cellular response to gamma radiation(GO:0071480) |
0.0 | 0.2 | GO:0051383 | kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383) |
0.0 | 0.4 | GO:0046579 | positive regulation of Ras protein signal transduction(GO:0046579) |
0.0 | 0.1 | GO:0018352 | protein-pyridoxal-5-phosphate linkage(GO:0018352) |
0.0 | 0.4 | GO:0045725 | positive regulation of glycogen biosynthetic process(GO:0045725) |
0.0 | 0.2 | GO:0035413 | positive regulation of catenin import into nucleus(GO:0035413) |
0.0 | 0.3 | GO:0009214 | cyclic nucleotide catabolic process(GO:0009214) |
0.0 | 0.1 | GO:0016266 | O-glycan processing(GO:0016266) |
0.0 | 0.1 | GO:0040037 | negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037) |
0.0 | 0.1 | GO:0060744 | thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744) |
0.0 | 0.2 | GO:0043113 | receptor clustering(GO:0043113) |
0.0 | 0.3 | GO:0032964 | collagen biosynthetic process(GO:0032964) |
0.0 | 1.2 | GO:0007588 | excretion(GO:0007588) |
0.0 | 0.6 | GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154) |
0.0 | 0.1 | GO:0032754 | positive regulation of interleukin-13 production(GO:0032736) positive regulation of interleukin-5 production(GO:0032754) |
0.0 | 0.0 | GO:0071025 | RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028) |
0.0 | 0.2 | GO:0006493 | protein O-linked glycosylation(GO:0006493) |
0.0 | 0.1 | GO:0015781 | pyrimidine nucleotide-sugar transport(GO:0015781) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.2 | GO:0043260 | laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260) |
0.1 | 0.6 | GO:0005899 | insulin receptor complex(GO:0005899) |
0.1 | 2.3 | GO:0016328 | lateral plasma membrane(GO:0016328) |
0.0 | 0.4 | GO:0043202 | lysosomal lumen(GO:0043202) |
0.0 | 0.6 | GO:0043073 | germ cell nucleus(GO:0043073) |
0.0 | 0.2 | GO:0031616 | spindle pole centrosome(GO:0031616) |
0.0 | 0.1 | GO:0035189 | Rb-E2F complex(GO:0035189) |
0.0 | 0.2 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
0.0 | 1.5 | GO:0008021 | synaptic vesicle(GO:0008021) |
0.0 | 0.1 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.4 | GO:0050692 | DBD domain binding(GO:0050692) |
0.1 | 2.3 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
0.1 | 0.4 | GO:0016997 | exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) |
0.1 | 0.6 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
0.1 | 0.4 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
0.1 | 0.3 | GO:0034187 | obsolete apolipoprotein E binding(GO:0034187) |
0.1 | 0.3 | GO:0004597 | peptide-aspartate beta-dioxygenase activity(GO:0004597) |
0.1 | 0.2 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
0.0 | 0.1 | GO:0035403 | histone kinase activity (H3-T6 specific)(GO:0035403) |
0.0 | 0.2 | GO:0090482 | vitamin transmembrane transporter activity(GO:0090482) |
0.0 | 0.1 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
0.0 | 0.1 | GO:0004119 | cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) |
0.0 | 0.4 | GO:0008242 | omega peptidase activity(GO:0008242) |
0.0 | 0.2 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
0.0 | 0.1 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
0.0 | 0.4 | GO:0003706 | obsolete ligand-regulated transcription factor activity(GO:0003706) |
0.0 | 0.2 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.0 | 0.5 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.0 | 0.2 | GO:0005114 | type II transforming growth factor beta receptor binding(GO:0005114) |
0.0 | 0.9 | GO:0097472 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472) |
0.0 | 0.6 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
0.0 | 1.4 | GO:0030165 | PDZ domain binding(GO:0030165) |
0.0 | 2.1 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.0 | 0.1 | GO:0042285 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
0.0 | 0.1 | GO:0008158 | hedgehog receptor activity(GO:0008158) |
0.0 | 1.1 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
0.0 | 0.2 | GO:0016565 | obsolete general transcriptional repressor activity(GO:0016565) |
0.0 | 0.1 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
0.0 | 0.1 | GO:0005157 | macrophage colony-stimulating factor receptor binding(GO:0005157) |
0.0 | 0.1 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) bicarbonate transmembrane transporter activity(GO:0015106) |
0.0 | 0.4 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
0.0 | 0.6 | GO:0005080 | protein kinase C binding(GO:0005080) |
0.0 | 0.1 | GO:0004791 | thioredoxin-disulfide reductase activity(GO:0004791) |
0.0 | 0.1 | GO:0001619 | obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619) |
0.0 | 0.5 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
0.0 | 0.1 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
0.0 | 0.5 | GO:0008301 | DNA binding, bending(GO:0008301) |
0.0 | 0.1 | GO:0004065 | arylsulfatase activity(GO:0004065) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 1.2 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
0.0 | 0.4 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
0.0 | 1.0 | SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES | Genes related to the insulin receptor pathway |