Motif ID: CEBPA
Z-value: 1.098
Transcription factors associated with CEBPA:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| CEBPA | ENSG00000245848.2 | CEBPA |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 1.9 | GO:0010989 | regulation of high-density lipoprotein particle clearance(GO:0010982) negative regulation of low-density lipoprotein particle clearance(GO:0010989) regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910) |
| 0.6 | 2.3 | GO:0001969 | activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969) positive regulation of activation of membrane attack complex(GO:0001970) positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259) |
| 0.5 | 2.0 | GO:0010727 | negative regulation of hydrogen peroxide metabolic process(GO:0010727) |
| 0.5 | 1.4 | GO:0009635 | response to herbicide(GO:0009635) |
| 0.4 | 3.7 | GO:0016998 | cell wall macromolecule catabolic process(GO:0016998) |
| 0.3 | 1.3 | GO:0071379 | cellular response to prostaglandin stimulus(GO:0071379) |
| 0.3 | 0.9 | GO:0052805 | histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805) |
| 0.3 | 0.9 | GO:1903961 | positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) positive regulation of anion transmembrane transport(GO:1903961) |
| 0.3 | 2.6 | GO:0051918 | negative regulation of fibrinolysis(GO:0051918) |
| 0.3 | 1.8 | GO:0045780 | positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852) |
| 0.2 | 2.9 | GO:0030299 | intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856) |
| 0.2 | 1.9 | GO:0030277 | epithelial structure maintenance(GO:0010669) maintenance of gastrointestinal epithelium(GO:0030277) |
| 0.2 | 1.8 | GO:0051552 | flavone metabolic process(GO:0051552) |
| 0.2 | 0.6 | GO:0071639 | positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559) positive regulation of monocyte chemotactic protein-1 production(GO:0071639) |
| 0.2 | 0.5 | GO:0090206 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
| 0.2 | 0.7 | GO:0019805 | quinolinate biosynthetic process(GO:0019805) |
| 0.2 | 0.7 | GO:0051409 | response to nitrosative stress(GO:0051409) |
| 0.1 | 1.2 | GO:0042448 | progesterone metabolic process(GO:0042448) |
| 0.1 | 1.3 | GO:0046653 | tetrahydrofolate metabolic process(GO:0046653) |
| 0.1 | 0.4 | GO:0007181 | transforming growth factor beta receptor complex assembly(GO:0007181) |
| 0.1 | 0.4 | GO:0048619 | embryonic hindgut morphogenesis(GO:0048619) |
| 0.1 | 2.4 | GO:0006825 | copper ion transport(GO:0006825) |
| 0.1 | 0.3 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.1 | 0.3 | GO:0051151 | negative regulation of smooth muscle cell differentiation(GO:0051151) |
| 0.1 | 1.0 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
| 0.1 | 1.0 | GO:0006107 | oxaloacetate metabolic process(GO:0006107) |
| 0.1 | 1.9 | GO:0006706 | steroid catabolic process(GO:0006706) |
| 0.1 | 2.6 | GO:1900047 | negative regulation of blood coagulation(GO:0030195) negative regulation of wound healing(GO:0061045) negative regulation of hemostasis(GO:1900047) |
| 0.1 | 1.1 | GO:0006491 | N-glycan processing(GO:0006491) |
| 0.1 | 0.4 | GO:0007614 | short-term memory(GO:0007614) |
| 0.1 | 0.1 | GO:0042905 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
| 0.1 | 0.9 | GO:0046415 | urate metabolic process(GO:0046415) |
| 0.1 | 4.7 | GO:0055088 | lipid homeostasis(GO:0055088) |
| 0.1 | 0.4 | GO:0009450 | gamma-aminobutyric acid catabolic process(GO:0009450) |
| 0.1 | 0.2 | GO:0000114 | obsolete regulation of transcription involved in G1 phase of mitotic cell cycle(GO:0000114) |
| 0.1 | 0.5 | GO:0006561 | proline biosynthetic process(GO:0006561) |
| 0.1 | 0.1 | GO:0002740 | negative regulation of cytokine secretion involved in immune response(GO:0002740) |
| 0.1 | 0.2 | GO:0050917 | sensory perception of umami taste(GO:0050917) |
| 0.1 | 0.2 | GO:0060586 | multicellular organismal iron ion homeostasis(GO:0060586) |
| 0.0 | 2.4 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.0 | 0.4 | GO:0032227 | negative regulation of synaptic transmission, dopaminergic(GO:0032227) |
| 0.0 | 0.5 | GO:0006027 | glycosaminoglycan catabolic process(GO:0006027) |
| 0.0 | 0.3 | GO:0045078 | positive regulation of interferon-gamma biosynthetic process(GO:0045078) |
| 0.0 | 0.2 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
| 0.0 | 0.2 | GO:0006065 | UDP-glucuronate biosynthetic process(GO:0006065) |
| 0.0 | 0.1 | GO:0010430 | ethanol catabolic process(GO:0006068) fatty acid omega-oxidation(GO:0010430) |
| 0.0 | 0.1 | GO:0046113 | nucleobase catabolic process(GO:0046113) |
| 0.0 | 0.2 | GO:0046952 | ketone body catabolic process(GO:0046952) |
| 0.0 | 0.2 | GO:0010957 | negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137) |
| 0.0 | 0.2 | GO:0032754 | positive regulation of interleukin-13 production(GO:0032736) positive regulation of interleukin-5 production(GO:0032754) |
| 0.0 | 0.2 | GO:0071731 | response to nitric oxide(GO:0071731) |
| 0.0 | 0.3 | GO:0015074 | DNA integration(GO:0015074) |
| 0.0 | 0.1 | GO:0002384 | hepatic immune response(GO:0002384) |
| 0.0 | 0.5 | GO:0032781 | positive regulation of ATPase activity(GO:0032781) |
| 0.0 | 2.7 | GO:0051592 | response to calcium ion(GO:0051592) |
| 0.0 | 0.1 | GO:0050955 | thermoception(GO:0050955) |
| 0.0 | 0.8 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
| 0.0 | 0.3 | GO:0032148 | activation of protein kinase B activity(GO:0032148) |
| 0.0 | 1.5 | GO:0043484 | regulation of RNA splicing(GO:0043484) |
| 0.0 | 0.1 | GO:0046532 | regulation of photoreceptor cell differentiation(GO:0046532) |
| 0.0 | 0.3 | GO:0032364 | oxygen homeostasis(GO:0032364) gas homeostasis(GO:0033483) |
| 0.0 | 0.1 | GO:0006207 | 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856) |
| 0.0 | 0.0 | GO:0061117 | negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117) |
| 0.0 | 0.4 | GO:0031000 | response to caffeine(GO:0031000) |
| 0.0 | 0.0 | GO:0045079 | negative regulation of chemokine biosynthetic process(GO:0045079) |
| 0.0 | 0.4 | GO:0060749 | mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377) |
| 0.0 | 1.4 | GO:0050821 | protein stabilization(GO:0050821) |
| 0.0 | 1.2 | GO:0030216 | keratinocyte differentiation(GO:0030216) |
| 0.0 | 0.2 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
| 0.0 | 0.2 | GO:0009070 | serine family amino acid biosynthetic process(GO:0009070) |
| 0.0 | 1.6 | GO:0008360 | regulation of cell shape(GO:0008360) |
| 0.0 | 0.1 | GO:0006538 | glutamate catabolic process(GO:0006538) |
| 0.0 | 0.6 | GO:0006953 | acute-phase response(GO:0006953) |
| 0.0 | 0.2 | GO:0008104 | protein localization(GO:0008104) |
| 0.0 | 0.1 | GO:0006287 | mitochondrial DNA replication(GO:0006264) base-excision repair, gap-filling(GO:0006287) |
| 0.0 | 1.0 | GO:0032526 | response to retinoic acid(GO:0032526) |
| 0.0 | 0.2 | GO:0009636 | response to toxic substance(GO:0009636) |
| 0.0 | 0.5 | GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154) |
| 0.0 | 0.7 | GO:0008206 | bile acid metabolic process(GO:0008206) |
| 0.0 | 0.3 | GO:0006730 | one-carbon metabolic process(GO:0006730) |
| 0.0 | 0.3 | GO:0031572 | G2 DNA damage checkpoint(GO:0031572) |
| 0.0 | 0.1 | GO:0071436 | sodium ion export(GO:0071436) |
| 0.0 | 0.1 | GO:0032099 | negative regulation of appetite(GO:0032099) |
| 0.0 | 0.1 | GO:0002087 | regulation of respiratory gaseous exchange by neurological system process(GO:0002087) regulation of respiratory system process(GO:0044065) |
| 0.0 | 0.1 | GO:0045329 | amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329) |
| 0.0 | 0.1 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
| 0.0 | 0.0 | GO:0071474 | cellular water homeostasis(GO:0009992) cellular hyperosmotic response(GO:0071474) |
| 0.0 | 0.0 | GO:0051497 | negative regulation of stress fiber assembly(GO:0051497) |
| 0.0 | 1.6 | GO:0006814 | sodium ion transport(GO:0006814) |
| 0.0 | 0.1 | GO:0032876 | regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023) |
| 0.0 | 1.1 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
| 0.0 | 0.3 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 1.8 | GO:0031904 | endosome lumen(GO:0031904) |
| 0.5 | 2.0 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 0.3 | 1.9 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
| 0.2 | 2.6 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.1 | 0.4 | GO:0032144 | 4-aminobutyrate transaminase complex(GO:0032144) |
| 0.1 | 0.4 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) beta-catenin-TCF complex(GO:1990907) |
| 0.1 | 0.9 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.0 | 0.8 | GO:0030057 | desmosome(GO:0030057) |
| 0.0 | 0.6 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.0 | 1.1 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.0 | 0.2 | GO:0016342 | catenin complex(GO:0016342) |
| 0.0 | 0.3 | GO:0005579 | membrane attack complex(GO:0005579) |
| 0.0 | 0.9 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 0.4 | GO:0019717 | obsolete synaptosome(GO:0019717) |
| 0.0 | 0.1 | GO:0032585 | multivesicular body membrane(GO:0032585) |
| 0.0 | 0.7 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.0 | 0.1 | GO:0031213 | RSF complex(GO:0031213) |
| 0.0 | 0.2 | GO:0071437 | invadopodium(GO:0071437) |
| 0.0 | 4.0 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.0 | 0.6 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.0 | 0.1 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.0 | 0.1 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 0.0 | 0.1 | GO:0042575 | DNA polymerase complex(GO:0042575) |
| 0.0 | 0.1 | GO:0005863 | striated muscle myosin thick filament(GO:0005863) |
| 0.0 | 0.5 | GO:0030018 | Z disc(GO:0030018) |
| 0.0 | 0.2 | GO:0005858 | axonemal dynein complex(GO:0005858) axoneme part(GO:0044447) |
| 0.0 | 0.2 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
| 0.0 | 0.1 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.0 | 0.2 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.0 | 1.2 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 0.5 | GO:0042645 | mitochondrial nucleoid(GO:0042645) |
| 0.0 | 0.2 | GO:0043234 | protein complex(GO:0043234) |
| 0.0 | 0.3 | GO:0016592 | mediator complex(GO:0016592) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 4.0 | GO:0047006 | 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) |
| 0.8 | 3.2 | GO:0003796 | lysozyme activity(GO:0003796) |
| 0.5 | 4.6 | GO:0004873 | asialoglycoprotein receptor activity(GO:0004873) |
| 0.5 | 1.9 | GO:0070653 | high-density lipoprotein particle receptor binding(GO:0070653) |
| 0.5 | 2.4 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.4 | 1.8 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
| 0.3 | 1.0 | GO:0004613 | phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613) |
| 0.3 | 2.0 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 0.3 | 2.7 | GO:0001848 | complement binding(GO:0001848) |
| 0.2 | 0.9 | GO:0016841 | ammonia-lyase activity(GO:0016841) |
| 0.2 | 1.3 | GO:0016647 | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647) |
| 0.2 | 1.0 | GO:0080030 | methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032) |
| 0.2 | 0.7 | GO:0016822 | hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823) |
| 0.2 | 1.8 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
| 0.1 | 0.7 | GO:0004906 | interferon-gamma receptor activity(GO:0004906) |
| 0.1 | 0.9 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 0.1 | 0.3 | GO:0004676 | 3-phosphoinositide-dependent protein kinase activity(GO:0004676) |
| 0.1 | 0.6 | GO:0004910 | interleukin-1, Type II, blocking receptor activity(GO:0004910) |
| 0.1 | 2.6 | GO:0043499 | obsolete eukaryotic cell surface binding(GO:0043499) |
| 0.1 | 0.4 | GO:0032145 | 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298) |
| 0.1 | 0.9 | GO:0005402 | sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) |
| 0.1 | 2.4 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.1 | 0.5 | GO:0004735 | pyrroline-5-carboxylate reductase activity(GO:0004735) |
| 0.1 | 0.4 | GO:0004998 | transferrin receptor activity(GO:0004998) |
| 0.1 | 0.1 | GO:0005539 | glycosaminoglycan binding(GO:0005539) |
| 0.1 | 0.6 | GO:0008732 | glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
| 0.1 | 0.3 | GO:0008907 | integrase activity(GO:0008907) |
| 0.1 | 0.2 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
| 0.1 | 0.4 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
| 0.1 | 0.2 | GO:0004756 | selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781) |
| 0.1 | 1.3 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.1 | 0.4 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
| 0.1 | 1.8 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.1 | 0.9 | GO:0005391 | sodium:potassium-exchanging ATPase activity(GO:0005391) |
| 0.1 | 0.6 | GO:0016595 | glutamate binding(GO:0016595) |
| 0.1 | 0.2 | GO:0004909 | interleukin-1, Type I, activating receptor activity(GO:0004909) |
| 0.1 | 0.2 | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity(GO:0003858) |
| 0.1 | 0.8 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 0.0 | 0.6 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.0 | 0.1 | GO:0010861 | thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375) |
| 0.0 | 1.5 | GO:0002020 | protease binding(GO:0002020) |
| 0.0 | 0.2 | GO:0005294 | neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294) |
| 0.0 | 0.2 | GO:0060961 | phospholipase D inhibitor activity(GO:0060961) |
| 0.0 | 0.1 | GO:0035276 | ethanol binding(GO:0035276) |
| 0.0 | 0.3 | GO:0031543 | peptidyl-proline dioxygenase activity(GO:0031543) |
| 0.0 | 2.1 | GO:0008146 | sulfotransferase activity(GO:0008146) |
| 0.0 | 0.1 | GO:0019862 | IgA binding(GO:0019862) |
| 0.0 | 3.5 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 0.6 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.0 | 0.2 | GO:0016714 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714) |
| 0.0 | 0.1 | GO:0004946 | bombesin receptor activity(GO:0004946) |
| 0.0 | 0.2 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.0 | 0.3 | GO:1901567 | icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567) |
| 0.0 | 0.1 | GO:0016524 | latrotoxin receptor activity(GO:0016524) |
| 0.0 | 0.4 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
| 0.0 | 0.1 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
| 0.0 | 0.5 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.0 | 1.2 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.0 | 0.2 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.0 | 0.4 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.0 | 0.6 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.0 | 0.1 | GO:0030151 | molybdenum ion binding(GO:0030151) |
| 0.0 | 0.3 | GO:0003993 | acid phosphatase activity(GO:0003993) |
| 0.0 | 0.1 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
| 0.0 | 0.2 | GO:0031419 | cobalamin binding(GO:0031419) |
| 0.0 | 0.1 | GO:0019981 | interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981) |
| 0.0 | 0.1 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) |
| 0.0 | 0.1 | GO:0004119 | cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) |
| 0.0 | 0.5 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.0 | 0.2 | GO:0005416 | sodium:amino acid symporter activity(GO:0005283) cation:amino acid symporter activity(GO:0005416) |
| 0.0 | 0.1 | GO:0004461 | lactose synthase activity(GO:0004461) |
| 0.0 | 0.3 | GO:0004467 | long-chain fatty acid-CoA ligase activity(GO:0004467) |
| 0.0 | 0.2 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.0 | 0.3 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.0 | 0.1 | GO:0004117 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) |
| 0.0 | 1.2 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 0.1 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.0 | 0.5 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.0 | 0.2 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.0 | SA_PROGRAMMED_CELL_DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.0 | 0.5 | SA_CASPASE_CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.0 | 0.6 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.0 | 0.5 | SA_B_CELL_RECEPTOR_COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
