Motif ID: CREB5_CREM_JUNB

Z-value: 2.185

Transcription factors associated with CREB5_CREM_JUNB:

Gene SymbolEntrez IDGene Name
CREB5 ENSG00000146592.12 CREB5
CREM ENSG00000095794.15 CREM
JUNB ENSG00000171223.4 JUNB






Network of associatons between targets according to the STRING database.



First level regulatory network of CREB5_CREM_JUNB

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_12696102 9.495 ENST00000527636.1
ENST00000527376.1
TEAD1

TEA domain family member 1 (SV40 transcriptional enhancer factor)

chr11_+_12695944 8.914 ENST00000361905.4
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr2_-_216300784 6.385 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1













fibronectin 1













chr9_-_99381660 5.343 ENST00000375240.3
ENST00000463569.1
CDC14B

cell division cycle 14B

chr16_+_3068393 5.126 ENST00000573001.1
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr4_+_75311019 4.995 ENST00000502307.1
AREG
amphiregulin
chr11_+_117070037 4.810 ENST00000392951.4
ENST00000525531.1
ENST00000278968.6
TAGLN


transgelin


chr4_+_75310851 4.615 ENST00000395748.3
ENST00000264487.2
AREG

amphiregulin

chr4_-_186456766 3.992 ENST00000284771.6
PDLIM3
PDZ and LIM domain 3
chr4_-_186456652 3.975 ENST00000284767.5
ENST00000284770.5
PDLIM3

PDZ and LIM domain 3

chr8_-_42065187 3.845 ENST00000270189.6
ENST00000352041.3
ENST00000220809.4
PLAT


plasminogen activator, tissue


chr6_+_139456226 3.837 ENST00000367658.2
HECA
headcase homolog (Drosophila)
chr3_+_62304712 3.691 ENST00000494481.1
C3orf14
chromosome 3 open reading frame 14
chr8_-_42065075 3.566 ENST00000429089.2
ENST00000519510.1
ENST00000429710.2
ENST00000524009.1
PLAT



plasminogen activator, tissue



chr3_+_62304648 3.494 ENST00000462069.1
ENST00000232519.5
ENST00000465142.1
C3orf14


chromosome 3 open reading frame 14


chr9_-_99382065 3.448 ENST00000265659.2
ENST00000375241.1
ENST00000375236.1
CDC14B


cell division cycle 14B


chr4_-_156298028 3.412 ENST00000433024.1
ENST00000379248.2
MAP9

microtubule-associated protein 9

chr4_+_75480629 3.402 ENST00000380846.3
AREGB
amphiregulin B
chrX_-_13956497 3.283 ENST00000398361.3
GPM6B
glycoprotein M6B
chr2_+_5832799 3.224 ENST00000322002.3
SOX11
SRY (sex determining region Y)-box 11
chr11_+_69455855 3.058 ENST00000227507.2
ENST00000536559.1
CCND1

cyclin D1

chr15_-_63674034 3.005 ENST00000344366.3
ENST00000422263.2
CA12

carbonic anhydrase XII

chr5_-_172198190 2.971 ENST00000239223.3
DUSP1
dual specificity phosphatase 1
chr8_+_98788003 2.951 ENST00000521545.2
LAPTM4B
lysosomal protein transmembrane 4 beta
chr5_-_57756087 2.858 ENST00000274289.3
PLK2
polo-like kinase 2
chr15_-_63674218 2.820 ENST00000178638.3
CA12
carbonic anhydrase XII
chr1_+_156030937 2.814 ENST00000361084.5
RAB25
RAB25, member RAS oncogene family
chr3_+_158991025 2.760 ENST00000337808.6
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr4_-_156297949 2.653 ENST00000515654.1
MAP9
microtubule-associated protein 9
chrX_-_13956737 2.609 ENST00000454189.2
GPM6B
glycoprotein M6B
chr4_-_156298087 2.558 ENST00000311277.4
MAP9
microtubule-associated protein 9
chr3_+_159570722 2.412 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr21_-_44846999 2.304 ENST00000270162.6
SIK1
salt-inducible kinase 1
chr10_-_99447024 2.300 ENST00000370626.3
AVPI1
arginine vasopressin-induced 1
chr16_-_79634595 2.211 ENST00000326043.4
ENST00000393350.1
MAF

v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog

chr3_-_99595037 2.185 ENST00000383694.2
FILIP1L
filamin A interacting protein 1-like
chr20_-_14318248 2.174 ENST00000378053.3
ENST00000341420.4
FLRT3

fibronectin leucine rich transmembrane protein 3

chr3_-_99594948 2.172 ENST00000471562.1
ENST00000495625.2
FILIP1L

filamin A interacting protein 1-like

chr11_-_35547151 2.152 ENST00000378878.3
ENST00000529303.1
ENST00000278360.3
PAMR1


peptidase domain containing associated with muscle regeneration 1


chr1_-_1293904 2.146 ENST00000309212.6
ENST00000342753.4
ENST00000445648.2
MXRA8


matrix-remodelling associated 8


chr19_+_16187085 2.130 ENST00000300933.4
TPM4
tropomyosin 4
chrX_-_10645773 2.072 ENST00000453318.2
MID1
midline 1 (Opitz/BBB syndrome)
chr10_+_123923105 2.063 ENST00000368999.1
TACC2
transforming, acidic coiled-coil containing protein 2
chr4_-_111558135 2.042 ENST00000394598.2
ENST00000394595.3
PITX2

paired-like homeodomain 2

chr19_+_16186903 2.022 ENST00000588507.1
TPM4
tropomyosin 4
chr16_+_22825475 1.981 ENST00000261374.3
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chrX_+_49832231 1.960 ENST00000376108.3
CLCN5
chloride channel, voltage-sensitive 5
chr12_+_54378923 1.954 ENST00000303460.4
HOXC10
homeobox C10
chr6_-_169654139 1.914 ENST00000366787.3
THBS2
thrombospondin 2
chr1_-_221915418 1.911 ENST00000323825.3
ENST00000366899.3
DUSP10

dual specificity phosphatase 10

chr15_-_30113676 1.848 ENST00000400011.2
TJP1
tight junction protein 1
chr2_+_241375069 1.828 ENST00000264039.2
GPC1
glypican 1
chr8_+_94929168 1.819 ENST00000518107.1
ENST00000396200.3
PDP1

pyruvate dehyrogenase phosphatase catalytic subunit 1

chr5_-_95297534 1.791 ENST00000513343.1
ENST00000431061.2
ELL2

elongation factor, RNA polymerase II, 2

chr8_+_94929077 1.783 ENST00000297598.4
ENST00000520614.1
PDP1

pyruvate dehyrogenase phosphatase catalytic subunit 1

chr8_+_94929110 1.747 ENST00000520728.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr4_+_85504075 1.742 ENST00000295887.5
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr2_-_238323007 1.732 ENST00000295550.4
COL6A3
collagen, type VI, alpha 3
chr17_+_41476327 1.729 ENST00000320033.4
ARL4D
ADP-ribosylation factor-like 4D
chr2_-_238322770 1.728 ENST00000472056.1
COL6A3
collagen, type VI, alpha 3
chr10_+_123922941 1.724 ENST00000360561.3
TACC2
transforming, acidic coiled-coil containing protein 2
chr2_-_238322800 1.693 ENST00000392004.3
ENST00000433762.1
ENST00000347401.3
ENST00000353578.4
ENST00000346358.4
ENST00000392003.2
COL6A3





collagen, type VI, alpha 3





chr11_-_111782696 1.664 ENST00000227251.3
ENST00000526180.1
CRYAB

crystallin, alpha B

chr20_-_56284816 1.659 ENST00000395819.3
ENST00000341744.3
PMEPA1

prostate transmembrane protein, androgen induced 1

chr10_+_123923205 1.651 ENST00000369004.3
ENST00000260733.3
TACC2

transforming, acidic coiled-coil containing protein 2

chr17_-_13505219 1.630 ENST00000284110.1
HS3ST3A1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr3_+_8543393 1.629 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LMCD1


LIM and cysteine-rich domains 1


chr18_+_61554932 1.608 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
SERPINB2


serpin peptidase inhibitor, clade B (ovalbumin), member 2


chr14_+_96671016 1.583 ENST00000542454.2
ENST00000554311.1
ENST00000306005.3
ENST00000539359.1
ENST00000553811.1
BDKRB2



RP11-404P21.8
bradykinin receptor B2



Uncharacterized protein
chr2_-_216257849 1.572 ENST00000456923.1
FN1
fibronectin 1
chrX_-_13835147 1.531 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr6_-_46293378 1.525 ENST00000330430.6
RCAN2
regulator of calcineurin 2
chr11_-_8832182 1.506 ENST00000527510.1
ENST00000528527.1
ENST00000528523.1
ENST00000313726.6
ST5



suppression of tumorigenicity 5



chr7_-_129592700 1.500 ENST00000472396.1
ENST00000355621.3
UBE2H

ubiquitin-conjugating enzyme E2H

chr7_+_100464760 1.493 ENST00000200457.4
TRIP6
thyroid hormone receptor interactor 6
chr8_-_18541603 1.483 ENST00000428502.2
PSD3
pleckstrin and Sec7 domain containing 3
chr10_+_124134201 1.475 ENST00000368990.3
ENST00000368988.1
ENST00000368989.2
ENST00000463663.2
PLEKHA1



pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1



chr7_-_37956409 1.463 ENST00000436072.2
SFRP4
secreted frizzled-related protein 4
chr1_+_99729813 1.455 ENST00000457765.1
LPPR4
Lipid phosphate phosphatase-related protein type 4
chr7_-_129592471 1.445 ENST00000473814.2
ENST00000490974.1
UBE2H

ubiquitin-conjugating enzyme E2H

chr7_+_134464414 1.430 ENST00000361901.2
CALD1
caldesmon 1
chr4_-_111544254 1.429 ENST00000306732.3
PITX2
paired-like homeodomain 2
chr2_+_220283091 1.406 ENST00000373960.3
DES
desmin
chr3_+_38206975 1.405 ENST00000446845.1
ENST00000311806.3
OXSR1

oxidative stress responsive 1

chr6_-_106773291 1.404 ENST00000343245.3
ATG5
autophagy related 5
chr16_-_10674528 1.345 ENST00000359543.3
EMP2
epithelial membrane protein 2
chr14_+_104095514 1.345 ENST00000348520.6
ENST00000380038.3
ENST00000389744.4
ENST00000557575.1
ENST00000553286.1
ENST00000347839.6
ENST00000555836.1
ENST00000334553.6
ENST00000246489.7
ENST00000557450.1
ENST00000452929.2
ENST00000554280.1
ENST00000445352.4
KLC1












kinesin light chain 1












chr11_-_35547572 1.305 ENST00000378880.2
PAMR1
peptidase domain containing associated with muscle regeneration 1
chr19_-_52227221 1.299 ENST00000222115.1
ENST00000540069.2
HAS1

hyaluronan synthase 1

chr8_-_18666360 1.295 ENST00000286485.8
PSD3
pleckstrin and Sec7 domain containing 3
chr16_+_2564254 1.282 ENST00000565223.1
ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr3_+_8543533 1.267 ENST00000454244.1
LMCD1
LIM and cysteine-rich domains 1
chr5_-_95297678 1.245 ENST00000237853.4
ELL2
elongation factor, RNA polymerase II, 2
chr8_-_18744528 1.225 ENST00000523619.1
PSD3
pleckstrin and Sec7 domain containing 3
chr9_+_97488939 1.224 ENST00000277198.2
ENST00000297979.5
C9orf3

chromosome 9 open reading frame 3

chr12_+_122150646 1.208 ENST00000449592.2
TMEM120B
transmembrane protein 120B
chr7_+_134464376 1.201 ENST00000454108.1
ENST00000361675.2
CALD1

caldesmon 1

chr5_+_174151536 1.196 ENST00000239243.6
ENST00000507785.1
MSX2

msh homeobox 2

chr22_-_36357671 1.190 ENST00000408983.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr11_-_111782484 1.171 ENST00000533971.1
CRYAB
crystallin, alpha B
chr15_+_68871308 1.156 ENST00000261861.5
CORO2B
coronin, actin binding protein, 2B
chr1_-_16482554 1.144 ENST00000358432.5
EPHA2
EPH receptor A2
chr17_-_39780819 1.141 ENST00000311208.8
KRT17
keratin 17
chr3_+_8543561 1.135 ENST00000397386.3
LMCD1
LIM and cysteine-rich domains 1
chr7_-_151433342 1.133 ENST00000433631.2
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr4_+_668348 1.128 ENST00000511290.1
MYL5
myosin, light chain 5, regulatory
chr7_-_151433393 1.124 ENST00000492843.1
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chrX_+_48432892 1.120 ENST00000376759.3
ENST00000430348.2
RBM3

RNA binding motif (RNP1, RRM) protein 3

chr1_+_152956549 1.111 ENST00000307122.2
SPRR1A
small proline-rich protein 1A
chr11_+_18343800 1.093 ENST00000453096.2
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chrX_+_12993336 1.089 ENST00000380635.1
TMSB4X
thymosin beta 4, X-linked
chr15_+_68871569 1.083 ENST00000566799.1
CORO2B
coronin, actin binding protein, 2B
chr1_-_59249732 1.081 ENST00000371222.2
JUN
jun proto-oncogene
chr2_+_30454390 1.074 ENST00000395323.3
ENST00000406087.1
ENST00000404397.1
LBH


limb bud and heart development


chr8_-_101964231 1.070 ENST00000521309.1
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr2_-_224467093 1.067 ENST00000305409.2
SCG2
secretogranin II
chr13_+_76334795 1.063 ENST00000526202.1
ENST00000465261.2
LMO7

LIM domain 7

chr5_-_1882858 1.052 ENST00000511126.1
ENST00000231357.2
IRX4

iroquois homeobox 4

chr11_-_107582775 1.038 ENST00000305991.2
SLN
sarcolipin
chr13_+_76334567 1.028 ENST00000321797.8
LMO7
LIM domain 7
chr12_+_10365404 1.013 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABARAPL1





GABA(A) receptor-associated protein like 1





chr1_-_242162375 0.986 ENST00000357246.3
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr6_-_106773491 0.986 ENST00000360666.4
ATG5
autophagy related 5
chr12_-_102455846 0.966 ENST00000545679.1
CCDC53
coiled-coil domain containing 53
chr6_+_39760129 0.965 ENST00000274867.4
DAAM2
dishevelled associated activator of morphogenesis 2
chr1_+_160175201 0.949 ENST00000368076.1
PEA15
phosphoprotein enriched in astrocytes 15
chr1_+_160175117 0.949 ENST00000360472.4
PEA15
phosphoprotein enriched in astrocytes 15
chr1_-_94050668 0.930 ENST00000539242.1
BCAR3
breast cancer anti-estrogen resistance 3
chr12_-_102455902 0.927 ENST00000240079.6
CCDC53
coiled-coil domain containing 53
chr22_+_38597889 0.887 ENST00000338483.2
ENST00000538320.1
ENST00000538999.1
ENST00000441709.1
MAFF



v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F



chr6_-_106773610 0.875 ENST00000369076.3
ENST00000369070.1
ATG5

autophagy related 5

chr8_-_95274536 0.874 ENST00000297596.2
ENST00000396194.2
GEM

GTP binding protein overexpressed in skeletal muscle

chr11_-_18343669 0.868 ENST00000396253.3
ENST00000349215.3
ENST00000438420.2
HPS5


Hermansky-Pudlak syndrome 5


chr19_+_45971246 0.849 ENST00000585836.1
ENST00000417353.2
ENST00000353609.3
ENST00000591858.1
ENST00000443841.2
ENST00000590335.1
FOSB





FBJ murine osteosarcoma viral oncogene homolog B





chr1_+_25071848 0.841 ENST00000374379.4
CLIC4
chloride intracellular channel 4
chr14_+_96722152 0.834 ENST00000216629.6
BDKRB1
bradykinin receptor B1
chr3_-_52001448 0.823 ENST00000461554.1
ENST00000395013.3
ENST00000428823.2
ENST00000483411.1
ENST00000461544.1
ENST00000355852.2
PCBP4





poly(rC) binding protein 4





chr8_+_132916318 0.812 ENST00000254624.5
ENST00000522709.1
EFR3A

EFR3 homolog A (S. cerevisiae)

chr16_+_2563871 0.806 ENST00000330398.4
ENST00000568562.1
ENST00000569317.1
ATP6V0C

ATP6C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c

Uncharacterized protein
chr1_-_201476274 0.800 ENST00000340006.2
CSRP1
cysteine and glycine-rich protein 1
chr21_+_39628852 0.794 ENST00000398938.2
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr11_+_18344106 0.792 ENST00000534641.1
ENST00000525831.1
ENST00000265963.4
GTF2H1


general transcription factor IIH, polypeptide 1, 62kDa


chr12_+_112856690 0.792 ENST00000392597.1
ENST00000351677.2
PTPN11

protein tyrosine phosphatase, non-receptor type 11

chr2_-_222436988 0.786 ENST00000409854.1
ENST00000281821.2
ENST00000392071.4
ENST00000443796.1
EPHA4



EPH receptor A4



chr16_-_4588469 0.777 ENST00000588381.1
ENST00000563332.2
CDIP1

cell death-inducing p53 target 1

chr2_-_220408430 0.733 ENST00000243776.6
CHPF
chondroitin polymerizing factor
chr8_+_26240414 0.732 ENST00000380629.2
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr8_-_101964265 0.727 ENST00000395958.2
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr2_-_28113965 0.724 ENST00000302188.3
RBKS
ribokinase
chr6_-_47277634 0.712 ENST00000296861.2
TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr2_+_54785485 0.712 ENST00000333896.5
SPTBN1
spectrin, beta, non-erythrocytic 1
chr17_+_66509019 0.699 ENST00000585981.1
ENST00000589480.1
ENST00000585815.1
PRKAR1A


protein kinase, cAMP-dependent, regulatory, type I, alpha


chr1_+_157963063 0.692 ENST00000360089.4
ENST00000368173.3
ENST00000392272.2
KIRREL


kin of IRRE like (Drosophila)


chr11_+_111782934 0.684 ENST00000304298.3
HSPB2
Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA.
chr4_+_47487285 0.679 ENST00000273859.3
ENST00000504445.1
ATP10D

ATPase, class V, type 10D

chr7_+_100273736 0.678 ENST00000412215.1
ENST00000393924.1
GNB2

guanine nucleotide binding protein (G protein), beta polypeptide 2

chr17_-_76899275 0.661 ENST00000322630.2
ENST00000586713.1
DDC8

Protein DDC8 homolog

chr6_-_159065741 0.657 ENST00000367085.3
ENST00000367089.3
DYNLT1

dynein, light chain, Tctex-type 1

chr15_-_30114231 0.655 ENST00000356107.6
ENST00000545208.2
TJP1

tight junction protein 1

chr21_+_39628655 0.652 ENST00000398925.1
ENST00000398928.1
ENST00000328656.4
ENST00000443341.1
KCNJ15



potassium inwardly-rectifying channel, subfamily J, member 15



chr19_+_45349432 0.651 ENST00000252485.4
PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chrX_-_13835461 0.649 ENST00000316715.4
ENST00000356942.5
GPM6B

glycoprotein M6B

chr4_-_79860506 0.643 ENST00000295462.3
ENST00000380645.4
ENST00000512733.1
PAQR3


progestin and adipoQ receptor family member III


chr3_-_107941230 0.638 ENST00000264538.3
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr16_+_31044413 0.630 ENST00000394998.1
STX4
syntaxin 4
chr3_+_130745769 0.630 ENST00000412440.2
NEK11
NIMA-related kinase 11
chr1_-_209979375 0.629 ENST00000367021.3
IRF6
interferon regulatory factor 6
chr6_-_56819385 0.612 ENST00000370754.5
ENST00000449297.2
DST

dystonin

chr17_-_63822563 0.602 ENST00000317442.8
CEP112
centrosomal protein 112kDa
chr7_-_142247606 0.595 ENST00000390361.3
TRBV7-3
T cell receptor beta variable 7-3
chr2_+_70142189 0.594 ENST00000264444.2
MXD1
MAX dimerization protein 1
chr3_+_130745688 0.591 ENST00000510769.1
ENST00000429253.2
ENST00000356918.4
ENST00000510688.1
ENST00000511262.1
ENST00000383366.4
NEK11





NIMA-related kinase 11





chr9_+_124088860 0.588 ENST00000373806.1
GSN
gelsolin
chr3_+_10068095 0.584 ENST00000287647.3
ENST00000383807.1
ENST00000383806.1
ENST00000419585.1
FANCD2



Fanconi anemia, complementation group D2



chr4_-_54930790 0.582 ENST00000263921.3
CHIC2
cysteine-rich hydrophobic domain 2
chr4_+_113739244 0.573 ENST00000503271.1
ENST00000503423.1
ENST00000506722.1
ANK2


ankyrin 2, neuronal


chr2_-_98280383 0.561 ENST00000289228.5
ACTR1B
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr3_-_48130707 0.555 ENST00000360240.6
ENST00000383737.4
MAP4

microtubule-associated protein 4

chr17_+_66508154 0.552 ENST00000358598.2
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr21_-_36421535 0.542 ENST00000416754.1
ENST00000437180.1
ENST00000455571.1
RUNX1


runt-related transcription factor 1


chr17_+_66508537 0.531 ENST00000392711.1
ENST00000585427.1
ENST00000589228.1
ENST00000536854.2
ENST00000588702.1
ENST00000589309.1
PRKAR1A





protein kinase, cAMP-dependent, regulatory, type I, alpha





chr4_+_113558272 0.529 ENST00000509061.1
ENST00000508577.1
ENST00000513553.1
LARP7


La ribonucleoprotein domain family, member 7


chr10_+_121410882 0.529 ENST00000369085.3
BAG3
BCL2-associated athanogene 3
chr19_-_59066327 0.527 ENST00000596708.1
ENST00000601220.1
ENST00000597848.1
CHMP2A


charged multivesicular body protein 2A


chr12_+_6833237 0.524 ENST00000229251.3
ENST00000539735.1
ENST00000538410.1
COPS7A


COP9 signalosome subunit 7A


chr1_-_1284730 0.522 ENST00000378888.5
DVL1
dishevelled segment polarity protein 1
chr2_+_70142232 0.522 ENST00000540449.1
MXD1
MAX dimerization protein 1
chr21_-_36421626 0.517 ENST00000300305.3
RUNX1
runt-related transcription factor 1
chr17_-_80231557 0.515 ENST00000392334.2
ENST00000314028.6
CSNK1D

casein kinase 1, delta

chr9_+_116298778 0.506 ENST00000462143.1
RGS3
regulator of G-protein signaling 3
chr19_-_59066452 0.502 ENST00000312547.2
CHMP2A
charged multivesicular body protein 2A
chr13_+_49822041 0.492 ENST00000538056.1
ENST00000251108.6
ENST00000444959.1
ENST00000429346.1
CDADC1



cytidine and dCMP deaminase domain containing 1



chr19_+_42772659 0.483 ENST00000572681.2
CIC
capicua transcriptional repressor
chr22_+_44319619 0.482 ENST00000216180.3
PNPLA3
patatin-like phospholipase domain containing 3
chr9_+_99212403 0.479 ENST00000375251.3
ENST00000375249.4
HABP4

hyaluronan binding protein 4

chr8_-_21966893 0.477 ENST00000522405.1
ENST00000522379.1
ENST00000309188.6
ENST00000521807.2
NUDT18



nudix (nucleoside diphosphate linked moiety X)-type motif 18



chr10_-_90967063 0.474 ENST00000371852.2
CH25H
cholesterol 25-hydroxylase
chr6_-_3157760 0.473 ENST00000333628.3
TUBB2A
tubulin, beta 2A class IIa
chr5_-_133304473 0.473 ENST00000231512.3
C5orf15
chromosome 5 open reading frame 15
chr11_-_73472096 0.468 ENST00000541588.1
ENST00000336083.3
ENST00000540771.1
ENST00000310653.6
RAB6A



RAB6A, member RAS oncogene family




Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.9 18.4 GO:0035329 hippo signaling(GO:0035329)
0.9 5.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.8 2.3 GO:0043276 anoikis(GO:0043276)
0.5 8.0 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.5 1.4 GO:0010966 regulation of phosphate transport(GO:0010966)
0.4 1.3 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.4 4.5 GO:0033327 Leydig cell differentiation(GO:0033327)
0.4 1.1 GO:0014028 notochord formation(GO:0014028) axial mesoderm morphogenesis(GO:0048319)
0.4 1.1 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.4 1.1 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.3 9.0 GO:0042730 fibrinolysis(GO:0042730)
0.3 2.0 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.3 5.3 GO:0050812 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.3 1.5 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.3 3.2 GO:0001706 endoderm formation(GO:0001706)
0.3 0.8 GO:0071277 cellular response to calcium ion(GO:0071277)
0.3 3.3 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.3 2.3 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.2 0.7 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.2 1.9 GO:0046325 negative regulation of glucose import(GO:0046325)
0.2 7.0 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.2 0.7 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.2 1.2 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.2 1.2 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.2 4.0 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.2 1.8 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.2 0.6 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.2 2.0 GO:0031268 pseudopodium organization(GO:0031268)
0.2 1.3 GO:0042989 sequestering of actin monomers(GO:0042989)
0.2 0.5 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.2 7.9 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.2 5.7 GO:0006730 one-carbon metabolic process(GO:0006730)
0.2 0.8 GO:0001661 conditioned taste aversion(GO:0001661)
0.2 3.0 GO:0014003 oligodendrocyte development(GO:0014003)
0.1 0.6 GO:0010332 response to gamma radiation(GO:0010332)
0.1 0.7 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.1 0.4 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 1.1 GO:0051294 establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.1 1.9 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 1.5 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.1 1.6 GO:0009651 response to salt stress(GO:0009651)
0.1 0.5 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.1 0.3 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.4 GO:0070527 platelet aggregation(GO:0070527)
0.1 0.3 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.1 0.4 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.1 0.7 GO:0010713 negative regulation of collagen metabolic process(GO:0010713) negative regulation of collagen biosynthetic process(GO:0032966) negative regulation of multicellular organismal metabolic process(GO:0044252)
0.1 0.4 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.1 0.2 GO:0035120 post-embryonic appendage morphogenesis(GO:0035120)
0.1 1.3 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 1.3 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 1.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.3 GO:0046604 regulation of mitotic centrosome separation(GO:0046602) positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.2 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.1 0.7 GO:0019321 pentose metabolic process(GO:0019321)
0.1 3.3 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 0.3 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 5.9 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 0.1 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.1 0.1 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.1 1.8 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.1 2.0 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.3 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 1.9 GO:0044349 nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349)
0.1 1.1 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.1 0.6 GO:0051014 actin filament severing(GO:0051014)
0.1 0.2 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1 0.9 GO:0007567 parturition(GO:0007567)
0.1 2.9 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 1.1 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.1 0.2 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.1 0.1 GO:0045760 positive regulation of action potential(GO:0045760)
0.0 0.7 GO:0008634 obsolete negative regulation of survival gene product expression(GO:0008634)
0.0 0.4 GO:0071692 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 1.8 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.0 0.4 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.4 GO:0001967 suckling behavior(GO:0001967)
0.0 2.3 GO:0007043 cell-cell junction assembly(GO:0007043)
0.0 0.6 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.4 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 1.1 GO:0031424 keratinization(GO:0031424)
0.0 3.3 GO:0009408 response to heat(GO:0009408)
0.0 7.4 GO:0007015 actin filament organization(GO:0007015)
0.0 0.1 GO:0014831 intestine smooth muscle contraction(GO:0014827) gastro-intestinal system smooth muscle contraction(GO:0014831)
0.0 0.3 GO:0006622 protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)
0.0 0.3 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 2.7 GO:0007588 excretion(GO:0007588)
0.0 0.2 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.3 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.6 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.1 GO:0042416 dopamine biosynthetic process(GO:0042416)
0.0 0.2 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.3 GO:0033523 histone monoubiquitination(GO:0010390) histone H2B ubiquitination(GO:0033523)
0.0 0.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 2.2 GO:0007623 circadian rhythm(GO:0007623)
0.0 0.2 GO:0021955 central nervous system projection neuron axonogenesis(GO:0021952) central nervous system neuron axonogenesis(GO:0021955)
0.0 7.4 GO:0007517 muscle organ development(GO:0007517)
0.0 0.4 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518) negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0 0.3 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.3 GO:0048268 negative regulation of receptor-mediated endocytosis(GO:0048261) clathrin coat assembly(GO:0048268)
0.0 0.9 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.4 GO:0007172 signal complex assembly(GO:0007172)
0.0 1.9 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.1 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.2 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.6 GO:0043473 pigmentation(GO:0043473)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0007616 long-term memory(GO:0007616) synaptic vesicle docking(GO:0016081) calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.0 GO:0010761 fibroblast migration(GO:0010761)
0.0 2.3 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.2 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.3 GO:0043507 positive regulation of JUN kinase activity(GO:0043507)
0.0 1.0 GO:0006914 autophagy(GO:0006914)
0.0 0.2 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.0 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.0 1.4 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.5 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.6 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.1 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.1 GO:0030813 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of nucleoside metabolic process(GO:0045979) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197) positive regulation of ATP metabolic process(GO:1903580)
0.0 0.1 GO:0051445 regulation of meiotic nuclear division(GO:0040020) regulation of meiotic cell cycle(GO:0051445)
0.0 0.4 GO:0046464 triglyceride catabolic process(GO:0019433) neutral lipid catabolic process(GO:0046461) acylglycerol catabolic process(GO:0046464)
0.0 0.1 GO:0071372 response to light intensity(GO:0009642) response to follicle-stimulating hormone(GO:0032354) cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.3 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.3 GO:0051928 positive regulation of calcium ion transport(GO:0051928)
0.0 0.5 GO:0050931 melanocyte differentiation(GO:0030318) pigment cell differentiation(GO:0050931)
0.0 0.1 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.1 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.2 GO:0050690 regulation of defense response to virus by virus(GO:0050690)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 8.0 GO:0005577 fibrinogen complex(GO:0005577)
0.4 5.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.4 3.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.3 1.5 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.3 2.0 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.3 2.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.2 4.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.2 2.8 GO:0031143 pseudopodium(GO:0031143)
0.2 2.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.2 1.9 GO:0005675 holo TFIIH complex(GO:0005675)
0.1 3.3 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 1.9 GO:0071203 WASH complex(GO:0071203)
0.1 2.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.6 GO:1990752 microtubule plus-end(GO:0035371) microtubule end(GO:1990752)
0.1 0.4 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 2.0 GO:0005776 autophagosome(GO:0005776)
0.1 0.4 GO:0031512 motile primary cilium(GO:0031512)
0.1 0.7 GO:0005915 zonula adherens(GO:0005915)
0.1 9.5 GO:0030017 sarcomere(GO:0030017)
0.1 0.1 GO:0097223 sperm part(GO:0097223)
0.1 2.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.7 GO:0001950 obsolete plasma membrane enriched fraction(GO:0001950)
0.1 0.3 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1 1.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.4 GO:0070820 tertiary granule(GO:0070820)
0.1 6.3 GO:0016459 myosin complex(GO:0016459)
0.1 1.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 2.2 GO:0030016 myofibril(GO:0030016)
0.1 0.6 GO:0005869 dynactin complex(GO:0005869)
0.1 20.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.3 GO:0001533 cornified envelope(GO:0001533)
0.0 0.4 GO:0034464 BBSome(GO:0034464)
0.0 5.1 GO:0001726 ruffle(GO:0001726)
0.0 0.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.6 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 5.4 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.5 GO:0008180 COP9 signalosome(GO:0008180)
0.0 13.2 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 3.0 GO:0005875 microtubule associated complex(GO:0005875)
0.0 1.4 GO:0030496 midbody(GO:0030496)
0.0 0.6 GO:0005802 trans-Golgi network(GO:0005802)
0.0 4.9 GO:0005819 spindle(GO:0005819)
0.0 0.3 GO:0030122 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.6 GO:0016234 inclusion body(GO:0016234)
0.0 1.2 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.7 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.2 GO:0070160 bicellular tight junction(GO:0005923) apical junction complex(GO:0043296) occluding junction(GO:0070160)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.2 GO:0030133 transport vesicle(GO:0030133)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.0 1.5 GO:0015934 large ribosomal subunit(GO:0015934)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 6.0 GO:0009986 cell surface(GO:0009986)
0.0 3.3 GO:0005815 microtubule organizing center(GO:0005815)
0.0 1.1 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0005811 lipid particle(GO:0005811)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.3 GO:0004741 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.9 2.7 GO:0004947 bradykinin receptor activity(GO:0004947)
0.6 3.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.6 1.7 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.5 2.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.4 1.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.3 5.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.3 3.0 GO:0016944 obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.3 0.8 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.2 1.5 GO:0042577 lipid phosphatase activity(GO:0042577)
0.2 9.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 4.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 2.2 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.1 1.8 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 7.3 GO:0005518 collagen binding(GO:0005518)
0.1 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 1.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 3.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 1.7 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 1.9 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 2.0 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 2.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 2.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.4 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 2.6 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.6 GO:0004457 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.1 0.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.3 GO:0016882 cyclo-ligase activity(GO:0016882)
0.1 1.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 1.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.4 GO:0034452 dynactin binding(GO:0034452)
0.1 0.8 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 7.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.3 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.2 GO:0042806 fucose binding(GO:0042806)
0.1 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.1 1.7 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.8 GO:0030552 cAMP binding(GO:0030552)
0.1 1.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 0.7 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.1 5.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 9.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.7 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.7 GO:0005521 lamin binding(GO:0005521)
0.0 1.1 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.3 GO:0042731 PH domain binding(GO:0042731)
0.0 3.9 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.2 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.3 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.6 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 7.0 GO:0008083 growth factor activity(GO:0008083)
0.0 0.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 12.8 GO:0016563 obsolete transcription activator activity(GO:0016563)
0.0 0.9 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 3.1 GO:0008135 translation factor activity, RNA binding(GO:0008135)
0.0 0.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.2 GO:0030276 clathrin binding(GO:0030276)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.2 GO:0043022 ribosome binding(GO:0043022)
0.0 0.4 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 1.7 GO:0051015 actin filament binding(GO:0051015)
0.0 1.8 GO:0008201 heparin binding(GO:0008201)
0.0 0.7 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 2.5 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.3 GO:0003709 obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0 1.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.6 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.1 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.0 3.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 3.1 GO:0016564 obsolete transcription repressor activity(GO:0016564)
0.0 0.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0031877 somatostatin receptor binding(GO:0031877)
0.0 8.7 GO:0008092 cytoskeletal protein binding(GO:0008092)
0.0 0.1 GO:0051378 serotonin binding(GO:0051378)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 2.9 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 1.9 GO:0003702 obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0 0.0 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403) polynucleotide phosphatase activity(GO:0098518)
0.0 0.4 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 1.2 GO:0031625 ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389)
0.0 0.4 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.0 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0 1.4 GO:0008194 UDP-glycosyltransferase activity(GO:0008194)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.5 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 3.0 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 1.8 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 4.5 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.0 1.7 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.0 0.3 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.0 1.1 SIG_CHEMOTAXIS Genes related to chemotaxis
0.0 0.4 ST_GA12_PATHWAY G alpha 12 Pathway