Motif ID: CREB5_CREM_JUNB
Z-value: 2.185
Transcription factors associated with CREB5_CREM_JUNB:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
CREB5 | ENSG00000146592.12 | CREB5 |
CREM | ENSG00000095794.15 | CREM |
JUNB | ENSG00000171223.4 | JUNB |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 4.0 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
0.9 | 18.4 | GO:0035329 | hippo signaling(GO:0035329) |
0.9 | 5.1 | GO:0006931 | substrate-dependent cell migration, cell attachment to substrate(GO:0006931) |
0.8 | 2.3 | GO:0043276 | anoikis(GO:0043276) |
0.5 | 8.0 | GO:0034446 | substrate adhesion-dependent cell spreading(GO:0034446) |
0.5 | 1.4 | GO:0010966 | regulation of phosphate transport(GO:0010966) |
0.4 | 1.3 | GO:0032988 | ribonucleoprotein complex disassembly(GO:0032988) |
0.4 | 4.5 | GO:0033327 | Leydig cell differentiation(GO:0033327) |
0.4 | 1.1 | GO:0014028 | notochord formation(GO:0014028) axial mesoderm morphogenesis(GO:0048319) |
0.4 | 1.1 | GO:0051365 | cellular response to potassium ion starvation(GO:0051365) |
0.4 | 1.1 | GO:0072677 | eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677) |
0.3 | 9.0 | GO:0042730 | fibrinolysis(GO:0042730) |
0.3 | 2.0 | GO:0021520 | spinal cord motor neuron cell fate specification(GO:0021520) |
0.3 | 5.3 | GO:0050812 | acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812) |
0.3 | 1.5 | GO:0008588 | release of cytoplasmic sequestered NF-kappaB(GO:0008588) |
0.3 | 3.2 | GO:0001706 | endoderm formation(GO:0001706) |
0.3 | 0.8 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
0.3 | 3.3 | GO:0055015 | ventricular cardiac muscle cell development(GO:0055015) |
0.3 | 2.3 | GO:0010799 | regulation of peptidyl-threonine phosphorylation(GO:0010799) positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
0.2 | 0.7 | GO:0090086 | negative regulation of protein deubiquitination(GO:0090086) |
0.2 | 1.9 | GO:0046325 | negative regulation of glucose import(GO:0046325) |
0.2 | 7.0 | GO:0031572 | G2 DNA damage checkpoint(GO:0031572) |
0.2 | 0.7 | GO:0060370 | susceptibility to T cell mediated cytotoxicity(GO:0060370) |
0.2 | 1.2 | GO:0071392 | cellular response to estradiol stimulus(GO:0071392) |
0.2 | 1.2 | GO:0031573 | intra-S DNA damage checkpoint(GO:0031573) |
0.2 | 4.0 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
0.2 | 1.8 | GO:0002553 | histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553) |
0.2 | 0.6 | GO:0002318 | myeloid progenitor cell differentiation(GO:0002318) |
0.2 | 2.0 | GO:0031268 | pseudopodium organization(GO:0031268) |
0.2 | 1.3 | GO:0042989 | sequestering of actin monomers(GO:0042989) |
0.2 | 0.5 | GO:0014022 | neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) |
0.2 | 7.9 | GO:0045740 | positive regulation of DNA replication(GO:0045740) |
0.2 | 5.7 | GO:0006730 | one-carbon metabolic process(GO:0006730) |
0.2 | 0.8 | GO:0001661 | conditioned taste aversion(GO:0001661) |
0.2 | 3.0 | GO:0014003 | oligodendrocyte development(GO:0014003) |
0.1 | 0.6 | GO:0010332 | response to gamma radiation(GO:0010332) |
0.1 | 0.7 | GO:0007182 | common-partner SMAD protein phosphorylation(GO:0007182) |
0.1 | 0.4 | GO:0001544 | initiation of primordial ovarian follicle growth(GO:0001544) |
0.1 | 1.1 | GO:0051294 | establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294) |
0.1 | 1.9 | GO:0043508 | negative regulation of JUN kinase activity(GO:0043508) |
0.1 | 1.5 | GO:0046839 | phospholipid dephosphorylation(GO:0046839) |
0.1 | 1.6 | GO:0009651 | response to salt stress(GO:0009651) |
0.1 | 0.5 | GO:0072385 | minus-end-directed organelle transport along microtubule(GO:0072385) |
0.1 | 0.3 | GO:0007000 | nucleolus organization(GO:0007000) |
0.1 | 0.4 | GO:0070527 | platelet aggregation(GO:0070527) |
0.1 | 0.3 | GO:0009396 | folic acid-containing compound biosynthetic process(GO:0009396) |
0.1 | 0.4 | GO:0051877 | pigment granule aggregation in cell center(GO:0051877) |
0.1 | 0.7 | GO:0010713 | negative regulation of collagen metabolic process(GO:0010713) negative regulation of collagen biosynthetic process(GO:0032966) negative regulation of multicellular organismal metabolic process(GO:0044252) |
0.1 | 0.4 | GO:0071480 | cellular response to gamma radiation(GO:0071480) |
0.1 | 0.2 | GO:0035120 | post-embryonic appendage morphogenesis(GO:0035120) |
0.1 | 1.3 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
0.1 | 1.3 | GO:0006657 | CDP-choline pathway(GO:0006657) |
0.1 | 1.3 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
0.1 | 0.3 | GO:0046604 | regulation of mitotic centrosome separation(GO:0046602) positive regulation of mitotic centrosome separation(GO:0046604) |
0.1 | 0.2 | GO:0060689 | cell differentiation involved in salivary gland development(GO:0060689) |
0.1 | 0.7 | GO:0019321 | pentose metabolic process(GO:0019321) |
0.1 | 3.3 | GO:0007368 | determination of left/right symmetry(GO:0007368) |
0.1 | 0.3 | GO:0000389 | mRNA 3'-splice site recognition(GO:0000389) |
0.1 | 5.9 | GO:0030049 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
0.1 | 0.1 | GO:0010837 | regulation of keratinocyte proliferation(GO:0010837) |
0.1 | 0.1 | GO:0033484 | nitric oxide homeostasis(GO:0033484) |
0.1 | 1.8 | GO:0034199 | activation of protein kinase A activity(GO:0034199) |
0.1 | 2.0 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.1 | 0.3 | GO:0010508 | positive regulation of autophagy(GO:0010508) |
0.1 | 1.9 | GO:0044349 | nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349) |
0.1 | 1.1 | GO:0051281 | positive regulation of release of sequestered calcium ion into cytosol(GO:0051281) |
0.1 | 0.6 | GO:0051014 | actin filament severing(GO:0051014) |
0.1 | 0.2 | GO:0043163 | cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229) |
0.1 | 0.9 | GO:0007567 | parturition(GO:0007567) |
0.1 | 2.9 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
0.1 | 1.1 | GO:0035196 | production of miRNAs involved in gene silencing by miRNA(GO:0035196) |
0.1 | 0.2 | GO:0032650 | regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) |
0.1 | 0.1 | GO:0045760 | positive regulation of action potential(GO:0045760) |
0.0 | 0.7 | GO:0008634 | obsolete negative regulation of survival gene product expression(GO:0008634) |
0.0 | 0.4 | GO:0071692 | sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116) |
0.0 | 1.8 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114) |
0.0 | 0.4 | GO:0010815 | bradykinin catabolic process(GO:0010815) |
0.0 | 0.4 | GO:0001967 | suckling behavior(GO:0001967) |
0.0 | 2.3 | GO:0007043 | cell-cell junction assembly(GO:0007043) |
0.0 | 0.6 | GO:0060644 | mammary gland epithelial cell differentiation(GO:0060644) |
0.0 | 0.1 | GO:0010792 | DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002) |
0.0 | 0.4 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
0.0 | 1.1 | GO:0031424 | keratinization(GO:0031424) |
0.0 | 3.3 | GO:0009408 | response to heat(GO:0009408) |
0.0 | 7.4 | GO:0007015 | actin filament organization(GO:0007015) |
0.0 | 0.1 | GO:0014831 | intestine smooth muscle contraction(GO:0014827) gastro-intestinal system smooth muscle contraction(GO:0014831) |
0.0 | 0.3 | GO:0006622 | protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666) |
0.0 | 0.3 | GO:0042797 | 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797) |
0.0 | 0.1 | GO:0008628 | hormone-mediated apoptotic signaling pathway(GO:0008628) |
0.0 | 2.7 | GO:0007588 | excretion(GO:0007588) |
0.0 | 0.2 | GO:0007341 | penetration of zona pellucida(GO:0007341) |
0.0 | 0.3 | GO:0007185 | transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185) |
0.0 | 0.6 | GO:0045104 | intermediate filament cytoskeleton organization(GO:0045104) |
0.0 | 0.1 | GO:0042416 | dopamine biosynthetic process(GO:0042416) |
0.0 | 0.2 | GO:0042149 | cellular response to glucose starvation(GO:0042149) |
0.0 | 0.2 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
0.0 | 0.3 | GO:0033523 | histone monoubiquitination(GO:0010390) histone H2B ubiquitination(GO:0033523) |
0.0 | 0.1 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
0.0 | 2.2 | GO:0007623 | circadian rhythm(GO:0007623) |
0.0 | 0.2 | GO:0021955 | central nervous system projection neuron axonogenesis(GO:0021952) central nervous system neuron axonogenesis(GO:0021955) |
0.0 | 7.4 | GO:0007517 | muscle organ development(GO:0007517) |
0.0 | 0.4 | GO:0032456 | endocytic recycling(GO:0032456) |
0.0 | 0.1 | GO:0042518 | negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518) negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532) |
0.0 | 0.3 | GO:0006376 | mRNA splice site selection(GO:0006376) |
0.0 | 0.3 | GO:0048268 | negative regulation of receptor-mediated endocytosis(GO:0048261) clathrin coat assembly(GO:0048268) |
0.0 | 0.9 | GO:0030520 | intracellular estrogen receptor signaling pathway(GO:0030520) |
0.0 | 0.4 | GO:0007172 | signal complex assembly(GO:0007172) |
0.0 | 1.9 | GO:0006368 | transcription elongation from RNA polymerase II promoter(GO:0006368) |
0.0 | 0.1 | GO:0021535 | cell migration in hindbrain(GO:0021535) |
0.0 | 0.2 | GO:0050847 | progesterone receptor signaling pathway(GO:0050847) |
0.0 | 0.6 | GO:0043473 | pigmentation(GO:0043473) |
0.0 | 0.1 | GO:0051005 | negative regulation of lipoprotein lipase activity(GO:0051005) |
0.0 | 0.1 | GO:0007616 | long-term memory(GO:0007616) synaptic vesicle docking(GO:0016081) calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
0.0 | 0.0 | GO:0010761 | fibroblast migration(GO:0010761) |
0.0 | 2.3 | GO:0000187 | activation of MAPK activity(GO:0000187) |
0.0 | 0.2 | GO:0060765 | regulation of androgen receptor signaling pathway(GO:0060765) |
0.0 | 0.3 | GO:0043507 | positive regulation of JUN kinase activity(GO:0043507) |
0.0 | 1.0 | GO:0006914 | autophagy(GO:0006914) |
0.0 | 0.2 | GO:0090083 | regulation of inclusion body assembly(GO:0090083) |
0.0 | 0.0 | GO:0046122 | purine deoxyribonucleoside metabolic process(GO:0046122) |
0.0 | 1.4 | GO:0019722 | calcium-mediated signaling(GO:0019722) |
0.0 | 0.5 | GO:0006699 | bile acid biosynthetic process(GO:0006699) |
0.0 | 0.6 | GO:0015914 | phospholipid transport(GO:0015914) |
0.0 | 0.1 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
0.0 | 0.1 | GO:0030813 | positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of nucleoside metabolic process(GO:0045979) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197) positive regulation of ATP metabolic process(GO:1903580) |
0.0 | 0.1 | GO:0051445 | regulation of meiotic nuclear division(GO:0040020) regulation of meiotic cell cycle(GO:0051445) |
0.0 | 0.4 | GO:0046464 | triglyceride catabolic process(GO:0019433) neutral lipid catabolic process(GO:0046461) acylglycerol catabolic process(GO:0046464) |
0.0 | 0.1 | GO:0071372 | response to light intensity(GO:0009642) response to follicle-stimulating hormone(GO:0032354) cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
0.0 | 0.3 | GO:0007413 | axonal fasciculation(GO:0007413) |
0.0 | 0.1 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
0.0 | 0.3 | GO:0051928 | positive regulation of calcium ion transport(GO:0051928) |
0.0 | 0.5 | GO:0050931 | melanocyte differentiation(GO:0030318) pigment cell differentiation(GO:0050931) |
0.0 | 0.1 | GO:0016574 | histone ubiquitination(GO:0016574) |
0.0 | 0.1 | GO:0070536 | protein K63-linked deubiquitination(GO:0070536) |
0.0 | 0.2 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 8.0 | GO:0005577 | fibrinogen complex(GO:0005577) |
0.4 | 5.2 | GO:0098647 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
0.4 | 3.3 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
0.3 | 1.5 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
0.3 | 2.0 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
0.3 | 2.1 | GO:0033179 | proton-transporting V-type ATPase, V0 domain(GO:0033179) |
0.2 | 4.5 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
0.2 | 2.8 | GO:0031143 | pseudopodium(GO:0031143) |
0.2 | 2.3 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
0.2 | 1.9 | GO:0005675 | holo TFIIH complex(GO:0005675) |
0.1 | 3.3 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
0.1 | 1.9 | GO:0071203 | WASH complex(GO:0071203) |
0.1 | 2.9 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.1 | 0.6 | GO:1990752 | microtubule plus-end(GO:0035371) microtubule end(GO:1990752) |
0.1 | 0.4 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
0.1 | 2.0 | GO:0005776 | autophagosome(GO:0005776) |
0.1 | 0.4 | GO:0031512 | motile primary cilium(GO:0031512) |
0.1 | 0.7 | GO:0005915 | zonula adherens(GO:0005915) |
0.1 | 9.5 | GO:0030017 | sarcomere(GO:0030017) |
0.1 | 0.1 | GO:0097223 | sperm part(GO:0097223) |
0.1 | 2.5 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
0.1 | 0.7 | GO:0001950 | obsolete plasma membrane enriched fraction(GO:0001950) |
0.1 | 0.3 | GO:0000306 | extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313) |
0.1 | 1.0 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
0.1 | 0.4 | GO:0070820 | tertiary granule(GO:0070820) |
0.1 | 6.3 | GO:0016459 | myosin complex(GO:0016459) |
0.1 | 1.8 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.1 | 2.2 | GO:0030016 | myofibril(GO:0030016) |
0.1 | 0.6 | GO:0005869 | dynactin complex(GO:0005869) |
0.1 | 20.6 | GO:0005667 | transcription factor complex(GO:0005667) |
0.0 | 1.3 | GO:0001533 | cornified envelope(GO:0001533) |
0.0 | 0.4 | GO:0034464 | BBSome(GO:0034464) |
0.0 | 5.1 | GO:0001726 | ruffle(GO:0001726) |
0.0 | 0.7 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
0.0 | 1.6 | GO:0008287 | protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293) |
0.0 | 5.4 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
0.0 | 0.5 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.0 | 13.2 | GO:0031012 | extracellular matrix(GO:0031012) |
0.0 | 1.2 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
0.0 | 3.0 | GO:0005875 | microtubule associated complex(GO:0005875) |
0.0 | 1.4 | GO:0030496 | midbody(GO:0030496) |
0.0 | 0.6 | GO:0005802 | trans-Golgi network(GO:0005802) |
0.0 | 4.9 | GO:0005819 | spindle(GO:0005819) |
0.0 | 0.3 | GO:0030122 | AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128) |
0.0 | 0.6 | GO:0016234 | inclusion body(GO:0016234) |
0.0 | 1.2 | GO:0031902 | late endosome membrane(GO:0031902) |
0.0 | 0.7 | GO:0036064 | ciliary basal body(GO:0036064) |
0.0 | 0.2 | GO:0070160 | bicellular tight junction(GO:0005923) apical junction complex(GO:0043296) occluding junction(GO:0070160) |
0.0 | 0.1 | GO:0070044 | synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044) |
0.0 | 0.2 | GO:0030133 | transport vesicle(GO:0030133) |
0.0 | 0.5 | GO:0016592 | mediator complex(GO:0016592) |
0.0 | 1.5 | GO:0015934 | large ribosomal subunit(GO:0015934) |
0.0 | 0.1 | GO:0070552 | BRISC complex(GO:0070552) |
0.0 | 6.0 | GO:0009986 | cell surface(GO:0009986) |
0.0 | 3.3 | GO:0005815 | microtubule organizing center(GO:0005815) |
0.0 | 1.1 | GO:0005882 | intermediate filament(GO:0005882) |
0.0 | 0.2 | GO:0005811 | lipid particle(GO:0005811) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.1 | 5.3 | GO:0004741 | magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
0.9 | 2.7 | GO:0004947 | bradykinin receptor activity(GO:0004947) |
0.6 | 3.2 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
0.6 | 1.7 | GO:0004605 | phosphatidate cytidylyltransferase activity(GO:0004605) |
0.5 | 2.3 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
0.4 | 1.1 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
0.3 | 5.8 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
0.3 | 3.0 | GO:0016944 | obsolete RNA polymerase II transcription elongation factor activity(GO:0016944) |
0.3 | 0.8 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
0.2 | 1.5 | GO:0042577 | lipid phosphatase activity(GO:0042577) |
0.2 | 9.7 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
0.2 | 4.0 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.2 | 2.2 | GO:0034483 | heparan sulfate sulfotransferase activity(GO:0034483) |
0.1 | 1.8 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
0.1 | 7.3 | GO:0005518 | collagen binding(GO:0005518) |
0.1 | 0.4 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
0.1 | 1.5 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
0.1 | 1.5 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
0.1 | 3.1 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
0.1 | 1.7 | GO:0030346 | protein phosphatase 2B binding(GO:0030346) |
0.1 | 1.9 | GO:0005003 | ephrin receptor activity(GO:0005003) |
0.1 | 2.0 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
0.1 | 2.8 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.1 | 2.1 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
0.1 | 0.4 | GO:0042328 | heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509) |
0.1 | 2.6 | GO:0005523 | tropomyosin binding(GO:0005523) |
0.1 | 0.6 | GO:0004457 | lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459) |
0.1 | 0.3 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
0.1 | 0.3 | GO:0016882 | cyclo-ligase activity(GO:0016882) |
0.1 | 1.9 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
0.1 | 1.5 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.1 | 0.4 | GO:0034452 | dynactin binding(GO:0034452) |
0.1 | 0.8 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
0.1 | 7.2 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.1 | 0.3 | GO:0008384 | IkappaB kinase activity(GO:0008384) |
0.1 | 0.2 | GO:0042806 | fucose binding(GO:0042806) |
0.1 | 0.5 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.1 | 1.7 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.1 | 1.8 | GO:0030552 | cAMP binding(GO:0030552) |
0.1 | 1.5 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
0.1 | 0.7 | GO:0036041 | long-chain fatty acid binding(GO:0036041) |
0.1 | 5.0 | GO:0008307 | structural constituent of muscle(GO:0008307) |
0.1 | 9.8 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.1 | 0.7 | GO:0070628 | proteasome binding(GO:0070628) |
0.0 | 0.1 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
0.0 | 0.7 | GO:0005521 | lamin binding(GO:0005521) |
0.0 | 1.1 | GO:0042056 | chemoattractant activity(GO:0042056) |
0.0 | 0.3 | GO:0042731 | PH domain binding(GO:0042731) |
0.0 | 3.9 | GO:0035257 | nuclear hormone receptor binding(GO:0035257) |
0.0 | 0.2 | GO:0042153 | obsolete RPTP-like protein binding(GO:0042153) |
0.0 | 0.3 | GO:0030515 | snoRNA binding(GO:0030515) |
0.0 | 0.6 | GO:0070063 | RNA polymerase binding(GO:0070063) |
0.0 | 7.0 | GO:0008083 | growth factor activity(GO:0008083) |
0.0 | 0.6 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
0.0 | 0.1 | GO:0043891 | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891) |
0.0 | 0.5 | GO:0005109 | frizzled binding(GO:0005109) |
0.0 | 12.8 | GO:0016563 | obsolete transcription activator activity(GO:0016563) |
0.0 | 0.9 | GO:0019003 | GDP binding(GO:0019003) |
0.0 | 0.1 | GO:0048406 | nerve growth factor binding(GO:0048406) |
0.0 | 0.5 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
0.0 | 3.1 | GO:0008135 | translation factor activity, RNA binding(GO:0008135) |
0.0 | 0.5 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
0.0 | 0.2 | GO:0030276 | clathrin binding(GO:0030276) |
0.0 | 0.2 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
0.0 | 0.5 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
0.0 | 0.2 | GO:0043022 | ribosome binding(GO:0043022) |
0.0 | 0.4 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
0.0 | 0.6 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
0.0 | 1.7 | GO:0051015 | actin filament binding(GO:0051015) |
0.0 | 1.8 | GO:0008201 | heparin binding(GO:0008201) |
0.0 | 0.7 | GO:0019200 | carbohydrate kinase activity(GO:0019200) |
0.0 | 2.5 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
0.0 | 0.3 | GO:0003709 | obsolete RNA polymerase III transcription factor activity(GO:0003709) |
0.0 | 1.8 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.0 | 0.6 | GO:0015026 | coreceptor activity(GO:0015026) |
0.0 | 0.1 | GO:0034617 | tetrahydrobiopterin binding(GO:0034617) |
0.0 | 3.6 | GO:0003714 | transcription corepressor activity(GO:0003714) |
0.0 | 3.1 | GO:0016564 | obsolete transcription repressor activity(GO:0016564) |
0.0 | 0.1 | GO:0016423 | tRNA (guanine) methyltransferase activity(GO:0016423) |
0.0 | 0.4 | GO:0005484 | SNAP receptor activity(GO:0005484) |
0.0 | 0.1 | GO:0031877 | somatostatin receptor binding(GO:0031877) |
0.0 | 8.7 | GO:0008092 | cytoskeletal protein binding(GO:0008092) |
0.0 | 0.1 | GO:0051378 | serotonin binding(GO:0051378) |
0.0 | 0.3 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
0.0 | 2.9 | GO:0030674 | protein binding, bridging(GO:0030674) |
0.0 | 0.1 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
0.0 | 0.1 | GO:0000268 | peroxisome targeting sequence binding(GO:0000268) |
0.0 | 1.9 | GO:0003702 | obsolete RNA polymerase II transcription factor activity(GO:0003702) |
0.0 | 0.0 | GO:0046403 | polynucleotide 3'-phosphatase activity(GO:0046403) polynucleotide phosphatase activity(GO:0098518) |
0.0 | 0.4 | GO:0005024 | transforming growth factor beta-activated receptor activity(GO:0005024) |
0.0 | 1.2 | GO:0031625 | ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389) |
0.0 | 0.4 | GO:0097472 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472) |
0.0 | 0.1 | GO:0003847 | 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847) |
0.0 | 0.1 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
0.0 | 0.1 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.0 | 0.7 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
0.0 | 0.0 | GO:0031702 | angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702) |
0.0 | 1.4 | GO:0008194 | UDP-glycosyltransferase activity(GO:0008194) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 3.5 | ST_MYOCYTE_AD_PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
0.1 | 3.0 | SA_G1_AND_S_PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
0.1 | 1.8 | ST_GRANULE_CELL_SURVIVAL_PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
0.1 | 4.5 | ST_P38_MAPK_PATHWAY | p38 MAPK Pathway |
0.0 | 1.7 | ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY | PI3K Pathway |
0.0 | 0.3 | ST_JAK_STAT_PATHWAY | Jak-STAT Pathway |
0.0 | 1.1 | SIG_CHEMOTAXIS | Genes related to chemotaxis |
0.0 | 0.4 | ST_GA12_PATHWAY | G alpha 12 Pathway |