Motif ID: DBP
Z-value: 1.307
Transcription factors associated with DBP:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| DBP | ENSG00000105516.6 | DBP |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 2.8 | GO:0035987 | endodermal cell fate commitment(GO:0001711) endodermal cell differentiation(GO:0035987) |
| 0.8 | 3.0 | GO:0071379 | cellular response to prostaglandin stimulus(GO:0071379) |
| 0.5 | 2.7 | GO:0045722 | response to muscle activity(GO:0014850) positive regulation of gluconeogenesis(GO:0045722) |
| 0.4 | 1.2 | GO:0033278 | cell proliferation in midbrain(GO:0033278) |
| 0.3 | 2.6 | GO:0032000 | positive regulation of fatty acid beta-oxidation(GO:0032000) |
| 0.3 | 4.3 | GO:0034446 | substrate adhesion-dependent cell spreading(GO:0034446) |
| 0.2 | 0.8 | GO:0050928 | negative regulation of positive chemotaxis(GO:0050928) |
| 0.2 | 0.9 | GO:0002328 | pro-B cell differentiation(GO:0002328) |
| 0.2 | 0.9 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
| 0.1 | 0.4 | GO:0070544 | regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188) histone H3-K36 demethylation(GO:0070544) |
| 0.1 | 0.9 | GO:0071699 | olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699) |
| 0.1 | 1.8 | GO:0034382 | chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) |
| 0.1 | 1.1 | GO:0006013 | mannose metabolic process(GO:0006013) |
| 0.1 | 0.7 | GO:0045953 | desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032) negative regulation of natural killer cell mediated immunity(GO:0002716) negative regulation of natural killer cell mediated cytotoxicity(GO:0045953) |
| 0.1 | 2.0 | GO:0006596 | polyamine biosynthetic process(GO:0006596) |
| 0.1 | 0.5 | GO:0010957 | negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137) |
| 0.1 | 0.5 | GO:0070669 | response to interleukin-2(GO:0070669) |
| 0.1 | 0.8 | GO:0045717 | negative regulation of fatty acid biosynthetic process(GO:0045717) |
| 0.1 | 0.3 | GO:0018377 | N-terminal protein myristoylation(GO:0006499) protein myristoylation(GO:0018377) |
| 0.1 | 0.4 | GO:0021794 | thalamus development(GO:0021794) |
| 0.1 | 0.4 | GO:0032754 | positive regulation of interleukin-13 production(GO:0032736) positive regulation of interleukin-5 production(GO:0032754) |
| 0.1 | 0.4 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
| 0.1 | 0.5 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064) |
| 0.1 | 0.4 | GO:0006422 | aspartyl-tRNA aminoacylation(GO:0006422) |
| 0.1 | 0.6 | GO:0006553 | lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554) |
| 0.1 | 0.4 | GO:0021615 | glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615) |
| 0.1 | 0.1 | GO:0060298 | positive regulation of sarcomere organization(GO:0060298) |
| 0.1 | 0.4 | GO:0042416 | dopamine biosynthetic process(GO:0042416) |
| 0.1 | 0.3 | GO:0003322 | pancreatic A cell development(GO:0003322) |
| 0.1 | 1.6 | GO:0042094 | interleukin-2 biosynthetic process(GO:0042094) |
| 0.0 | 0.3 | GO:0000183 | chromatin silencing at rDNA(GO:0000183) |
| 0.0 | 1.8 | GO:0006309 | DNA catabolic process, endonucleolytic(GO:0000737) apoptotic DNA fragmentation(GO:0006309) |
| 0.0 | 0.4 | GO:0031641 | regulation of myelination(GO:0031641) |
| 0.0 | 0.7 | GO:0007032 | endosome organization(GO:0007032) |
| 0.0 | 0.1 | GO:0060896 | commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898) neural plate anterior/posterior regionalization(GO:0021999) otic placode formation(GO:0043049) neural plate pattern specification(GO:0060896) neural plate regionalization(GO:0060897) |
| 0.0 | 0.1 | GO:0051151 | negative regulation of smooth muscle cell differentiation(GO:0051151) |
| 0.0 | 0.3 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.0 | 0.2 | GO:0070365 | hepatocyte differentiation(GO:0070365) |
| 0.0 | 0.3 | GO:0006621 | protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437) |
| 0.0 | 0.6 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
| 0.0 | 0.2 | GO:0010658 | striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667) |
| 0.0 | 0.8 | GO:0006024 | glycosaminoglycan biosynthetic process(GO:0006024) |
| 0.0 | 0.2 | GO:0033169 | histone H3-K9 demethylation(GO:0033169) |
| 0.0 | 0.8 | GO:0050918 | positive chemotaxis(GO:0050918) |
| 0.0 | 1.0 | GO:0046324 | regulation of glucose import(GO:0046324) |
| 0.0 | 0.9 | GO:0030183 | B cell differentiation(GO:0030183) |
| 0.0 | 0.2 | GO:0045616 | regulation of keratinocyte differentiation(GO:0045616) |
| 0.0 | 0.1 | GO:0051895 | negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392) |
| 0.0 | 0.7 | GO:0048813 | dendrite morphogenesis(GO:0048813) |
| 0.0 | 0.3 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.0 | 1.7 | GO:0008203 | cholesterol metabolic process(GO:0008203) |
| 0.0 | 0.4 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.0 | 0.3 | GO:0042116 | macrophage activation(GO:0042116) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 3.0 | GO:0031904 | endosome lumen(GO:0031904) |
| 0.4 | 2.6 | GO:0045179 | apical cortex(GO:0045179) |
| 0.4 | 4.3 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.2 | 0.7 | GO:0000306 | extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313) |
| 0.1 | 1.0 | GO:0000300 | obsolete peripheral to membrane of membrane fraction(GO:0000300) |
| 0.1 | 1.2 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.1 | 2.2 | GO:0030867 | rough endoplasmic reticulum membrane(GO:0030867) |
| 0.1 | 2.7 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.1 | 2.3 | GO:0034362 | low-density lipoprotein particle(GO:0034362) |
| 0.1 | 0.3 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.1 | 1.8 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.0 | 0.4 | GO:0071437 | podosome(GO:0002102) invadopodium(GO:0071437) |
| 0.0 | 0.3 | GO:0016342 | catenin complex(GO:0016342) |
| 0.0 | 0.2 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.0 | 0.3 | GO:0005579 | membrane attack complex(GO:0005579) |
| 0.0 | 0.3 | GO:0000780 | condensed nuclear chromosome, centromeric region(GO:0000780) |
| 0.0 | 0.7 | GO:0000786 | nucleosome(GO:0000786) |
| 0.0 | 0.3 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 2.2 | GO:0008475 | procollagen-lysine 5-dioxygenase activity(GO:0008475) |
| 0.7 | 2.6 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.4 | 1.1 | GO:0004476 | mannose-6-phosphate isomerase activity(GO:0004476) |
| 0.3 | 1.0 | GO:0016524 | latrotoxin receptor activity(GO:0016524) |
| 0.2 | 3.0 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
| 0.2 | 1.4 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.2 | 1.3 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 0.2 | 2.8 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.2 | 0.5 | GO:0004796 | thromboxane-A synthase activity(GO:0004796) |
| 0.2 | 4.0 | GO:0030169 | low-density lipoprotein particle binding(GO:0030169) |
| 0.2 | 3.0 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.1 | 0.2 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
| 0.1 | 0.8 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
| 0.1 | 1.6 | GO:0004908 | interleukin-1 receptor activity(GO:0004908) |
| 0.1 | 0.3 | GO:0004379 | glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107) |
| 0.1 | 0.3 | GO:0016563 | obsolete transcription activator activity(GO:0016563) |
| 0.1 | 0.7 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.1 | 4.3 | GO:0005518 | collagen binding(GO:0005518) |
| 0.1 | 0.4 | GO:0004815 | aspartate-tRNA ligase activity(GO:0004815) |
| 0.1 | 0.8 | GO:0055103 | ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106) |
| 0.1 | 0.3 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.1 | 0.5 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.1 | 0.3 | GO:0005046 | KDEL sequence binding(GO:0005046) |
| 0.1 | 1.3 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.1 | 0.4 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.1 | 0.7 | GO:0031701 | angiotensin receptor binding(GO:0031701) |
| 0.1 | 0.3 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) core promoter sequence-specific DNA binding(GO:0001046) core promoter binding(GO:0001047) |
| 0.1 | 0.5 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.0 | 2.2 | GO:0070405 | ammonium ion binding(GO:0070405) |
| 0.0 | 0.3 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.0 | 0.3 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.0 | 0.3 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.0 | 0.2 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.0 | 0.3 | GO:0042153 | obsolete RPTP-like protein binding(GO:0042153) alpha-catenin binding(GO:0045294) |
| 0.0 | 0.3 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.0 | 0.8 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.0 | 0.7 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.0 | 0.1 | GO:0004946 | bombesin receptor activity(GO:0004946) |
| 0.0 | 0.2 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 0.0 | 0.4 | GO:0008503 | benzodiazepine receptor activity(GO:0008503) |
| 0.0 | 0.7 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.0 | 0.9 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.0 | 0.2 | GO:0090599 | alpha-glucosidase activity(GO:0090599) |
| 0.0 | 0.6 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 0.1 | GO:0030955 | potassium ion binding(GO:0030955) |
| 0.0 | 0.2 | GO:0030297 | transmembrane receptor protein tyrosine kinase activator activity(GO:0030297) |
| 0.0 | 0.6 | GO:0016646 | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646) |
| 0.0 | 0.8 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.0 | 0.1 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.0 | 0.2 | GO:0019841 | retinol binding(GO:0019841) |
| 0.0 | 0.2 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.0 | 0.1 | GO:0016004 | phospholipase activator activity(GO:0016004) |
| 0.0 | 1.8 | GO:0030674 | protein binding, bridging(GO:0030674) |
| 0.0 | 0.4 | GO:1990782 | receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782) |
| 0.0 | 0.1 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.0 | 1.1 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.8 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.0 | 1.1 | ST_ADRENERGIC | Adrenergic Pathway |
