Motif ID: DBX2_HLX

Z-value: 1.184

Transcription factors associated with DBX2_HLX:

Gene SymbolEntrez IDGene Name
DBX2 ENSG00000185610.6 DBX2
HLX ENSG00000136630.11 HLX






Network of associatons between targets according to the STRING database.



First level regulatory network of DBX2_HLX

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_130126165 2.779 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
MEST


mesoderm specific transcript


chr7_+_130126012 2.683 ENST00000341441.5
MEST
mesoderm specific transcript
chr1_+_81771806 2.115 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2





latrophilin 2





chr6_-_52859046 1.957 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
GSTA4


glutathione S-transferase alpha 4


chr19_+_50016610 1.934 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr17_+_1674982 1.776 ENST00000572048.1
ENST00000573763.1
SERPINF1

serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1

chr11_+_5710919 1.699 ENST00000379965.3
ENST00000425490.1
TRIM22

tripartite motif containing 22

chr8_-_13134045 1.621 ENST00000512044.2
DLC1
deleted in liver cancer 1
chr11_-_63376013 1.608 ENST00000540943.1
PLA2G16
phospholipase A2, group XVI
chr5_-_125930929 1.530 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
ALDH7A1


aldehyde dehydrogenase 7 family, member A1


chr4_-_110723194 1.440 ENST00000394635.3
CFI
complement factor I
chr19_+_50016411 1.355 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
FCGRT


Fc fragment of IgG, receptor, transporter, alpha


chr16_+_14802801 1.273 ENST00000526520.1
ENST00000531598.2
NPIPA3

nuclear pore complex interacting protein family, member A3

chr2_+_11696464 1.218 ENST00000234142.5
GREB1
growth regulation by estrogen in breast cancer 1
chr6_+_114178512 1.187 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr3_-_123512688 1.179 ENST00000475616.1
MYLK
myosin light chain kinase
chr4_-_110723134 1.158 ENST00000510800.1
ENST00000512148.1
CFI

complement factor I

chr10_+_5135981 1.128 ENST00000380554.3
AKR1C3
aldo-keto reductase family 1, member C3
chr2_+_85811525 1.104 ENST00000306384.4
VAMP5
vesicle-associated membrane protein 5
chr16_-_28634874 1.079 ENST00000395609.1
ENST00000350842.4
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr12_+_26348429 1.066 ENST00000242729.2
SSPN
sarcospan
chr8_+_97597148 1.054 ENST00000521590.1
SDC2
syndecan 2
chr17_-_64225508 1.052 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr12_+_26348246 1.039 ENST00000422622.2
SSPN
sarcospan
chr11_-_104827425 1.039 ENST00000393150.3
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr8_+_98900132 0.995 ENST00000520016.1
MATN2
matrilin 2
chr7_+_134576317 0.982 ENST00000424922.1
ENST00000495522.1
CALD1

caldesmon 1

chrX_-_106243451 0.978 ENST00000355610.4
ENST00000535534.1
MORC4

MORC family CW-type zinc finger 4

chr3_-_194072019 0.964 ENST00000429275.1
ENST00000323830.3
CPN2

carboxypeptidase N, polypeptide 2

chr3_-_114790179 0.959 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr12_-_91505608 0.945 ENST00000266718.4
LUM
lumican
chr14_-_53331239 0.926 ENST00000553663.1
FERMT2
fermitin family member 2
chr12_-_91573132 0.917 ENST00000550563.1
ENST00000546370.1
DCN

decorin

chr15_+_25200074 0.891 ENST00000390687.4
ENST00000584968.1
ENST00000346403.6
ENST00000554227.2
SNRPN



small nuclear ribonucleoprotein polypeptide N



chr20_-_33735070 0.870 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
EDEM2


ER degradation enhancer, mannosidase alpha-like 2


chr16_-_30122717 0.848 ENST00000566613.1
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr7_-_87342564 0.846 ENST00000265724.3
ENST00000416177.1
ABCB1

ATP-binding cassette, sub-family B (MDR/TAP), member 1

chr12_+_81110684 0.837 ENST00000228644.3
MYF5
myogenic factor 5
chr14_-_54423529 0.835 ENST00000245451.4
ENST00000559087.1
BMP4

bone morphogenetic protein 4

chr16_-_28937027 0.833 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr3_-_48130707 0.830 ENST00000360240.6
ENST00000383737.4
MAP4

microtubule-associated protein 4

chr5_-_146781153 0.820 ENST00000520473.1
DPYSL3
dihydropyrimidinase-like 3
chr7_+_134576151 0.818 ENST00000393118.2
CALD1
caldesmon 1
chr15_+_25200108 0.815 ENST00000579070.1
ENST00000577565.1
ENST00000577949.1
ENST00000338094.6
ENST00000338327.4
SNRPN

SNURF


small nuclear ribonucleoprotein polypeptide N

SNRPN upstream reading frame protein


chr11_-_104817919 0.805 ENST00000533252.1
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr1_-_89591749 0.792 ENST00000370466.3
GBP2
guanylate binding protein 2, interferon-inducible
chr10_-_52645379 0.726 ENST00000395489.2
A1CF
APOBEC1 complementation factor
chr2_+_11674213 0.724 ENST00000381486.2
GREB1
growth regulation by estrogen in breast cancer 1
chr11_-_2162468 0.677 ENST00000434045.2
IGF2
insulin-like growth factor 2 (somatomedin A)
chr2_+_102413726 0.670 ENST00000350878.4
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr1_-_110283138 0.669 ENST00000256594.3
GSTM3
glutathione S-transferase mu 3 (brain)
chr13_-_46679185 0.665 ENST00000439329.3
CPB2
carboxypeptidase B2 (plasma)
chr13_-_46679144 0.662 ENST00000181383.4
CPB2
carboxypeptidase B2 (plasma)
chr14_-_25479811 0.659 ENST00000550887.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr12_+_75874580 0.646 ENST00000456650.3
GLIPR1
GLI pathogenesis-related 1
chr12_+_75874460 0.646 ENST00000266659.3
GLIPR1
GLI pathogenesis-related 1
chr4_+_69962185 0.643 ENST00000305231.7
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr4_+_146403912 0.642 ENST00000507367.1
ENST00000394092.2
ENST00000515385.1
SMAD1


SMAD family member 1


chr12_+_75874984 0.628 ENST00000550491.1
GLIPR1
GLI pathogenesis-related 1
chr4_+_74301880 0.620 ENST00000395792.2
ENST00000226359.2
AFP

alpha-fetoprotein

chr9_+_116207007 0.618 ENST00000374140.2
RGS3
regulator of G-protein signaling 3
chr4_+_69962212 0.611 ENST00000508661.1
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr6_-_52859968 0.610 ENST00000370959.1
GSTA4
glutathione S-transferase alpha 4
chrX_-_130423200 0.587 ENST00000361420.3
IGSF1
immunoglobulin superfamily, member 1
chr1_+_84630645 0.579 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr4_+_69681710 0.569 ENST00000265403.7
ENST00000458688.2
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr6_-_152639479 0.560 ENST00000356820.4
SYNE1
spectrin repeat containing, nuclear envelope 1
chr11_+_35201826 0.557 ENST00000531873.1
CD44
CD44 molecule (Indian blood group)
chr5_+_82767487 0.551 ENST00000343200.5
ENST00000342785.4
VCAN

versican

chr6_+_121756809 0.551 ENST00000282561.3
GJA1
gap junction protein, alpha 1, 43kDa
chr10_-_95241951 0.551 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
MYOF


myoferlin


chr10_-_95242044 0.541 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
MYOF


myoferlin


chr15_+_58724184 0.538 ENST00000433326.2
LIPC
lipase, hepatic
chr2_-_225811747 0.524 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr4_-_186456652 0.511 ENST00000284767.5
ENST00000284770.5
PDLIM3

PDZ and LIM domain 3

chr4_+_155484155 0.504 ENST00000509493.1
FGB
fibrinogen beta chain
chr4_-_186456766 0.498 ENST00000284771.6
PDLIM3
PDZ and LIM domain 3
chr11_-_13517565 0.495 ENST00000282091.1
ENST00000529816.1
PTH

parathyroid hormone

chr2_+_161993412 0.493 ENST00000259075.2
ENST00000432002.1
TANK

TRAF family member-associated NFKB activator

chr11_+_101983176 0.484 ENST00000524575.1
YAP1
Yes-associated protein 1
chr11_-_124670550 0.484 ENST00000239614.4
MSANTD2
Myb/SANT-like DNA-binding domain containing 2
chr6_-_52705641 0.473 ENST00000370989.2
GSTA5
glutathione S-transferase alpha 5
chr2_+_170366203 0.466 ENST00000284669.1
KLHL41
kelch-like family member 41
chr4_+_71063641 0.465 ENST00000514097.1
ODAM
odontogenic, ameloblast asssociated
chr5_+_82767284 0.461 ENST00000265077.3
VCAN
versican
chr11_-_128894053 0.458 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr1_-_48937838 0.456 ENST00000371847.3
SPATA6
spermatogenesis associated 6
chr15_+_69452959 0.453 ENST00000261858.2
GLCE
glucuronic acid epimerase
chr20_+_11871433 0.452 ENST00000399006.2
ENST00000405977.1
BTBD3

BTB (POZ) domain containing 3

chr6_-_112575687 0.447 ENST00000521398.1
ENST00000424408.2
ENST00000243219.3
LAMA4


laminin, alpha 4


chr6_-_112575912 0.445 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
LAMA4


laminin, alpha 4


chr3_+_158787041 0.445 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1


IQCJ-SCHIP1 readthrough


chr16_-_66584059 0.423 ENST00000417693.3
ENST00000544898.1
ENST00000569718.1
ENST00000527284.1
ENST00000299697.7
ENST00000451102.2
TK2





thymidine kinase 2, mitochondrial





chr16_-_21436459 0.418 ENST00000448012.2
ENST00000504841.2
ENST00000419180.2
NPIPB3


nuclear pore complex interacting protein family, member B3


chr20_+_11871371 0.409 ENST00000254977.3
BTBD3
BTB (POZ) domain containing 3
chr16_-_15474904 0.408 ENST00000534094.1
NPIPA5
nuclear pore complex interacting protein family, member A5
chr2_-_111334678 0.405 ENST00000329516.3
ENST00000330331.5
ENST00000446930.1
RGPD6


RANBP2-like and GRIP domain containing 6


chr5_+_140762268 0.392 ENST00000518325.1
PCDHGA7
protocadherin gamma subfamily A, 7
chrX_-_131547625 0.373 ENST00000394311.2
MBNL3
muscleblind-like splicing regulator 3
chr21_-_43735628 0.373 ENST00000291525.10
ENST00000518498.1
TFF3

trefoil factor 3 (intestinal)

chr1_-_92371839 0.367 ENST00000370399.2
TGFBR3
transforming growth factor, beta receptor III
chr6_+_28092338 0.352 ENST00000340487.4
ZSCAN16
zinc finger and SCAN domain containing 16
chr6_-_52710893 0.349 ENST00000284562.2
GSTA5
glutathione S-transferase alpha 5
chr16_-_29415350 0.345 ENST00000524087.1
NPIPB11
nuclear pore complex interacting protein family, member B11
chr10_-_116444371 0.343 ENST00000533213.2
ENST00000369252.4
ABLIM1

actin binding LIM protein 1

chr14_+_57046500 0.337 ENST00000261556.6
TMEM260
transmembrane protein 260
chr14_-_90085458 0.335 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
FOXN3


forkhead box N3


chrX_-_131547596 0.330 ENST00000538204.1
ENST00000370849.3
MBNL3

muscleblind-like splicing regulator 3

chr15_-_99789736 0.328 ENST00000560235.1
ENST00000394132.2
ENST00000560860.1
ENST00000558078.1
ENST00000394136.1
ENST00000262074.4
ENST00000558613.1
ENST00000394130.1
ENST00000560772.1
TTC23








tetratricopeptide repeat domain 23








chrM_+_12331 0.321 ENST00000361567.2
MT-ND5
mitochondrially encoded NADH dehydrogenase 5
chr4_+_155484103 0.317 ENST00000302068.4
FGB
fibrinogen beta chain
chr16_+_48278178 0.313 ENST00000285737.4
ENST00000535754.1
LONP2

lon peptidase 2, peroxisomal

chr19_+_42212501 0.311 ENST00000398599.4
CEACAM5
carcinoembryonic antigen-related cell adhesion molecule 5
chr19_+_13842559 0.311 ENST00000586600.1
CCDC130
coiled-coil domain containing 130
chrX_-_13835147 0.309 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr6_-_112575838 0.303 ENST00000455073.1
LAMA4
laminin, alpha 4
chr10_+_122610687 0.294 ENST00000263461.6
WDR11
WD repeat domain 11
chr11_+_22696314 0.289 ENST00000532398.1
ENST00000433790.1
GAS2

growth arrest-specific 2

chr11_+_22689648 0.288 ENST00000278187.3
GAS2
growth arrest-specific 2
chr6_-_47277634 0.288 ENST00000296861.2
TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr16_-_29934558 0.287 ENST00000568995.1
ENST00000566413.1
KCTD13

potassium channel tetramerization domain containing 13

chr16_+_22524844 0.286 ENST00000538606.1
ENST00000424340.1
ENST00000517539.1
ENST00000528249.1
NPIPB5



nuclear pore complex interacting protein family, member B5



chr6_+_116601265 0.285 ENST00000452085.3
DSE
dermatan sulfate epimerase
chr16_-_21868739 0.284 ENST00000415645.2
NPIPB4
nuclear pore complex interacting protein family, member B4
chr20_+_30697298 0.280 ENST00000398022.2
TM9SF4
transmembrane 9 superfamily protein member 4
chr9_+_34652164 0.279 ENST00000441545.2
ENST00000553620.1
IL11RA

interleukin 11 receptor, alpha

chr6_+_158733692 0.278 ENST00000367094.2
ENST00000367097.3
TULP4

tubby like protein 4

chr2_+_109237717 0.276 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr16_+_24549014 0.274 ENST00000564314.1
ENST00000567686.1
RBBP6

retinoblastoma binding protein 6

chr10_+_90424196 0.274 ENST00000394375.3
ENST00000608620.1
ENST00000238983.4
ENST00000355843.2
LIPF



lipase, gastric



chr6_-_133035185 0.270 ENST00000367928.4
VNN1
vanin 1
chr2_-_179672142 0.268 ENST00000342992.6
ENST00000360870.5
ENST00000460472.2
ENST00000589042.1
ENST00000591111.1
ENST00000342175.6
ENST00000359218.5
TTN






titin






chr10_-_112678976 0.263 ENST00000448814.1
BBIP1
BBSome interacting protein 1
chr1_-_48937821 0.260 ENST00000396199.3
SPATA6
spermatogenesis associated 6
chr6_+_26365443 0.259 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
BTN3A2





butyrophilin, subfamily 3, member A2





chr16_+_28763108 0.257 ENST00000357796.3
ENST00000550983.1
NPIPB9

nuclear pore complex interacting protein family, member B9

chr5_+_156696362 0.253 ENST00000377576.3
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr3_+_138340067 0.250 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr11_-_18548426 0.250 ENST00000357193.3
ENST00000536719.1
TSG101

tumor susceptibility 101

chrX_-_114252193 0.249 ENST00000243213.1
IL13RA2
interleukin 13 receptor, alpha 2
chr16_-_21868978 0.247 ENST00000357370.5
ENST00000451409.1
ENST00000341400.7
ENST00000518761.4
NPIPB4



nuclear pore complex interacting protein family, member B4



chr7_-_137028534 0.247 ENST00000348225.2
PTN
pleiotrophin
chr19_-_43382142 0.245 ENST00000597058.1
PSG1
pregnancy specific beta-1-glycoprotein 1
chr1_-_21377383 0.244 ENST00000374935.3
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr8_+_132952112 0.242 ENST00000520362.1
ENST00000519656.1
EFR3A

EFR3 homolog A (S. cerevisiae)

chr3_-_11685345 0.237 ENST00000430365.2
VGLL4
vestigial like 4 (Drosophila)
chr11_-_59950519 0.237 ENST00000528851.1
MS4A6A
membrane-spanning 4-domains, subfamily A, member 6A
chr6_+_153552455 0.236 ENST00000392385.2
AL590867.1
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr7_+_138943265 0.236 ENST00000483726.1
UBN2
ubinuclein 2
chr11_-_35287243 0.233 ENST00000464522.2
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr5_+_95066823 0.232 ENST00000506817.1
ENST00000379982.3
RHOBTB3

Rho-related BTB domain containing 3

chr7_-_137028498 0.231 ENST00000393083.2
PTN
pleiotrophin
chr16_-_66583701 0.225 ENST00000527800.1
ENST00000525974.1
ENST00000563369.2
TK2


thymidine kinase 2, mitochondrial


chr2_+_239335449 0.225 ENST00000264607.4
ASB1
ankyrin repeat and SOCS box containing 1
chr14_-_35591433 0.224 ENST00000261475.5
ENST00000555644.1
PPP2R3C

protein phosphatase 2, regulatory subunit B'', gamma

chr12_-_12503156 0.212 ENST00000543314.1
ENST00000396349.3
MANSC1

MANSC domain containing 1

chr17_+_67498538 0.211 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr14_-_68283291 0.200 ENST00000555452.1
ENST00000347230.4
ZFYVE26

zinc finger, FYVE domain containing 26

chr12_-_8803128 0.198 ENST00000543467.1
MFAP5
microfibrillar associated protein 5
chr20_+_1099233 0.198 ENST00000246015.4
ENST00000335877.6
ENST00000438768.2
PSMF1


proteasome (prosome, macropain) inhibitor subunit 1 (PI31)


chr6_-_112575758 0.196 ENST00000431543.2
ENST00000453937.2
ENST00000368638.4
ENST00000389463.4
LAMA4



laminin, alpha 4



chr7_-_44122063 0.195 ENST00000335195.6
ENST00000395831.3
ENST00000414235.1
ENST00000452049.1
ENST00000242248.5
POLM




polymerase (DNA directed), mu




chr18_-_10701979 0.195 ENST00000538948.1
ENST00000285141.4
PIEZO2

piezo-type mechanosensitive ion channel component 2

chr7_+_142498725 0.193 ENST00000466254.1
TRBC2
T cell receptor beta constant 2
chr10_+_91152303 0.193 ENST00000371804.3
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr3_-_185538849 0.191 ENST00000421047.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr10_-_112678692 0.191 ENST00000605742.1
BBIP1
BBSome interacting protein 1
chr2_+_109204909 0.190 ENST00000393310.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr19_-_51920952 0.190 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
SIGLEC10





sialic acid binding Ig-like lectin 10





chr14_+_57046530 0.190 ENST00000536419.1
ENST00000538838.1
TMEM260

transmembrane protein 260

chr2_+_109204743 0.190 ENST00000332345.6
LIMS1
LIM and senescent cell antigen-like domains 1
chr2_+_102953608 0.188 ENST00000311734.2
ENST00000409584.1
IL1RL1

interleukin 1 receptor-like 1

chr16_+_28648975 0.187 ENST00000529716.1
NPIPB8
nuclear pore complex interacting protein family, member B8
chr2_+_210517895 0.187 ENST00000447185.1
MAP2
microtubule-associated protein 2
chr10_-_79789291 0.183 ENST00000372371.3
POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr10_+_124320156 0.182 ENST00000338354.3
ENST00000344338.3
ENST00000330163.4
ENST00000368909.3
ENST00000368955.3
ENST00000368956.2
DMBT1





deleted in malignant brain tumors 1





chr2_-_58468437 0.181 ENST00000403676.1
ENST00000427708.2
ENST00000403295.3
ENST00000446381.1
ENST00000417361.1
ENST00000233741.4
ENST00000402135.3
ENST00000540646.1
ENST00000449070.1
FANCL








Fanconi anemia, complementation group L








chr3_-_160823158 0.181 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
B3GALNT1


beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)


chr5_-_139726181 0.181 ENST00000507104.1
ENST00000230990.6
HBEGF

heparin-binding EGF-like growth factor

chr8_-_93115445 0.177 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chrX_+_1710484 0.174 ENST00000313871.3
ENST00000381261.3
AKAP17A

A kinase (PRKA) anchor protein 17A

chr3_+_138340049 0.174 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr18_-_51750948 0.174 ENST00000583046.1
ENST00000398398.2
MBD2

methyl-CpG binding domain protein 2

chr16_+_67880574 0.171 ENST00000219169.4
NUTF2
nuclear transport factor 2
chr5_-_74162605 0.170 ENST00000389156.4
ENST00000510496.1
ENST00000380515.3
FAM169A


family with sequence similarity 169, member A


chr16_-_28374829 0.168 ENST00000532254.1
NPIPB6
nuclear pore complex interacting protein family, member B6
chr1_+_12976450 0.166 ENST00000361079.2
PRAMEF7
PRAME family member 7
chr10_-_112678904 0.163 ENST00000423273.1
ENST00000436562.1
ENST00000447005.1
ENST00000454061.1
BBIP1



BBSome interacting protein 1



chrX_+_55744228 0.159 ENST00000262850.7
RRAGB
Ras-related GTP binding B
chr19_-_53758094 0.157 ENST00000601828.1
ENST00000598513.1
ENST00000599012.1
ENST00000333952.4
ENST00000598806.1
ZNF677




zinc finger protein 677




chr1_+_221051699 0.157 ENST00000366903.6
HLX
H2.0-like homeobox
chr1_-_67142710 0.156 ENST00000502413.2
AL139147.1
Uncharacterized protein
chr11_+_7618413 0.153 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr3_-_160823040 0.151 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
B3GALNT1






beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)






chr6_-_52668605 0.151 ENST00000334575.5
GSTA1
glutathione S-transferase alpha 1
chr2_+_211342432 0.149 ENST00000430249.2
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr5_-_10761206 0.149 ENST00000432074.2
ENST00000230895.6
DAP

death-associated protein

chr12_+_14572070 0.149 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
ATF7IP




activating transcription factor 7 interacting protein




chr1_+_196788887 0.147 ENST00000367421.3
ENST00000320493.5
ENST00000367424.4
CFHR2
CFHR1

complement factor H-related 2
complement factor H-related 1

chr19_+_16940198 0.146 ENST00000248054.5
ENST00000596802.1
ENST00000379803.1
SIN3B


SIN3 transcription regulator family member B



Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0007614 short-term memory(GO:0007614)
0.3 0.8 GO:0048389 intermediate mesoderm development(GO:0048389) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) bud dilation involved in lung branching(GO:0060503) branch elongation involved in ureteric bud branching(GO:0060681) regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) pulmonary artery morphogenesis(GO:0061156) cell proliferation involved in mesonephros development(GO:0061209) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) negative regulation of mesonephros development(GO:0061218) pattern specification involved in mesonephros development(GO:0061227) renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) BMP signaling pathway involved in nephric duct formation(GO:0071893) glomerular visceral epithelial cell development(GO:0072015) comma-shaped body morphogenesis(GO:0072049) regulation of branch elongation involved in ureteric bud branching(GO:0072095) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in kidney development(GO:0072098) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) glomerulus morphogenesis(GO:0072102) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104) mesenchymal cell proliferation involved in ureteric bud development(GO:0072138) nephric duct formation(GO:0072179) ureter urothelium development(GO:0072190) ureter epithelial cell differentiation(GO:0072192) ureter morphogenesis(GO:0072197) metanephric comma-shaped body morphogenesis(GO:0072278) glomerular epithelial cell development(GO:0072310) negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.2 2.5 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.2 0.7 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 1.1 GO:0001778 plasma membrane repair(GO:0001778)
0.2 1.5 GO:0006553 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.2 1.2 GO:0060414 aorta development(GO:0035904) aorta morphogenesis(GO:0035909) aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 0.7 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 1.6 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.6 GO:0051503 purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503)
0.1 0.4 GO:0060318 definitive erythrocyte differentiation(GO:0060318)
0.1 0.3 GO:0019731 antibacterial humoral response(GO:0019731)
0.1 0.6 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.8 GO:0042693 muscle cell fate commitment(GO:0042693)
0.1 0.5 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.1 0.3 GO:0030205 dermatan sulfate metabolic process(GO:0030205) dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.6 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.1 0.5 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 0.3 GO:0031034 skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 1.7 GO:0070206 protein trimerization(GO:0070206)
0.1 0.5 GO:0060242 contact inhibition(GO:0060242)
0.1 0.7 GO:0031017 exocrine pancreas development(GO:0031017)
0.1 0.6 GO:0042448 progesterone metabolic process(GO:0042448)
0.1 0.3 GO:0051541 elastin metabolic process(GO:0051541)
0.1 0.2 GO:0051097 negative regulation of helicase activity(GO:0051097) cellular response to exogenous dsRNA(GO:0071360)
0.1 3.5 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 0.5 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.5 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.6 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.3 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.1 5.1 GO:0007498 mesoderm development(GO:0007498)
0.0 0.2 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.8 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.1 GO:0030859 polarized epithelial cell differentiation(GO:0030859) establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.6 GO:1901797 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0 1.1 GO:0031000 response to caffeine(GO:0031000)
0.0 2.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 1.4 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 1.1 GO:0051923 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) sulfation(GO:0051923)
0.0 3.4 GO:0019882 antigen processing and presentation(GO:0019882)
0.0 0.9 GO:0008347 glial cell migration(GO:0008347)
0.0 0.1 GO:0070365 hepatocyte differentiation(GO:0070365) cellular response to oleic acid(GO:0071400)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.3 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.1 GO:0046520 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.0 0.1 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.6 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.2 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.2 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 1.1 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.6 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.3 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.1 GO:0051917 regulation of fibrinolysis(GO:0051917)
0.0 0.1 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.7 GO:0006693 prostaglandin metabolic process(GO:0006693)
0.0 0.1 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.3 GO:0007566 embryo implantation(GO:0007566)
0.0 0.3 GO:0007584 response to nutrient(GO:0007584)
0.0 0.3 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 2.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.3 GO:0051319 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.3 GO:0071230 cellular response to amino acid stimulus(GO:0071230)
0.0 1.5 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 1.3 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537) proline catabolic process(GO:0006562)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.4 GO:0007586 digestion(GO:0007586)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.5 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.7 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.1 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.6 GO:0042384 cilium assembly(GO:0042384)
0.0 0.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 0.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:1901998 tetracycline transport(GO:0015904) antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0 0.7 GO:0050821 protein stabilization(GO:0050821)
0.0 0.2 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.0 0.1 GO:0019627 urea metabolic process(GO:0019627)
0.0 0.1 GO:0030813 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of nucleoside metabolic process(GO:0045979) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197) positive regulation of ATP metabolic process(GO:1903580)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 3.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.8 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 1.5 GO:0005606 laminin-1 complex(GO:0005606)
0.1 0.4 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 1.0 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.9 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 2.1 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.6 GO:0034464 BBSome(GO:0034464)
0.1 1.2 GO:0043073 germ cell nucleus(GO:0043073)
0.1 0.9 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.6 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0000806 Y chromosome(GO:0000806)
0.0 0.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 1.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 2.2 GO:0005884 actin filament(GO:0005884)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.3 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 1.3 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0030673 axolemma(GO:0030673)
0.0 1.1 GO:0042641 actomyosin(GO:0042641)
0.0 0.6 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 2.2 GO:0005925 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.0 0.3 GO:0005771 multivesicular body(GO:0005771)
0.0 1.0 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 1.1 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.2 GO:0001527 microfibril(GO:0001527)
0.0 0.8 GO:0030426 growth cone(GO:0030426)
0.0 0.2 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.5 GO:0009295 nucleoid(GO:0009295)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.3 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.7 2.1 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.4 1.1 GO:0047718 indanol dehydrogenase activity(GO:0047718)
0.2 1.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 0.6 GO:0004797 thymidine kinase activity(GO:0004797)
0.2 0.8 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.2 1.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.2 1.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.1 1.6 GO:0043274 phospholipase binding(GO:0043274)
0.1 4.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.8 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 0.6 GO:0034711 inhibin binding(GO:0034711)
0.1 0.3 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.1 1.5 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 0.8 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.8 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.8 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.7 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 0.2 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.1 1.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.8 GO:0005523 tropomyosin binding(GO:0005523)
0.1 2.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.6 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 0.3 GO:0017159 pantetheine hydrolase activity(GO:0017159) GPI anchor binding(GO:0034235)
0.1 1.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.6 GO:0005243 gap junction channel activity(GO:0005243)
0.0 1.0 GO:0043499 obsolete eukaryotic cell surface binding(GO:0043499)
0.0 0.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.6 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.6 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:0008907 integrase activity(GO:0008907)
0.0 0.4 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.6 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 1.6 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.9 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.3 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.3 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.7 GO:0019239 deaminase activity(GO:0019239)
0.0 0.1 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.2 GO:0000339 RNA cap binding(GO:0000339)
0.0 1.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.0 0.8 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.5 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 1.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.1 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.5 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.1 GO:0016595 glutamate binding(GO:0016595)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 1.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.0 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 2.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.3 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton