Motif ID: DLX1_HOXA3_BARX2
Z-value: 1.960
Transcription factors associated with DLX1_HOXA3_BARX2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
BARX2 | ENSG00000043039.5 | BARX2 |
DLX1 | ENSG00000144355.10 | DLX1 |
HOXA3 | ENSG00000105997.18 | HOXA3 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.0 | GO:1901419 | regulation of response to alcohol(GO:1901419) |
0.6 | 1.9 | GO:0010107 | potassium ion import(GO:0010107) |
0.6 | 1.8 | GO:1904358 | positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358) |
0.5 | 2.2 | GO:0010900 | regulation of phosphatidylcholine catabolic process(GO:0010899) negative regulation of phosphatidylcholine catabolic process(GO:0010900) |
0.5 | 2.7 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
0.5 | 1.5 | GO:0001907 | cytolysis by symbiont of host cells(GO:0001897) killing by symbiont of host cells(GO:0001907) hemolysis by symbiont of host erythrocytes(GO:0019836) disruption by symbiont of host cell(GO:0044004) hemolysis in other organism(GO:0044179) cytolysis in other organism(GO:0051715) cytolysis in other organism involved in symbiotic interaction(GO:0051801) hemolysis in other organism involved in symbiotic interaction(GO:0052331) |
0.4 | 1.2 | GO:1903961 | positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) positive regulation of anion transmembrane transport(GO:1903961) |
0.4 | 1.2 | GO:0002378 | immunoglobulin biosynthetic process(GO:0002378) |
0.4 | 1.9 | GO:0010957 | negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137) |
0.4 | 1.5 | GO:0018352 | protein-pyridoxal-5-phosphate linkage(GO:0018352) |
0.4 | 2.9 | GO:0034392 | negative regulation of smooth muscle cell apoptotic process(GO:0034392) |
0.3 | 0.9 | GO:0051661 | maintenance of centrosome location(GO:0051661) |
0.3 | 3.3 | GO:0006975 | DNA damage induced protein phosphorylation(GO:0006975) |
0.3 | 0.9 | GO:0002431 | Fc receptor mediated stimulatory signaling pathway(GO:0002431) regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) |
0.3 | 7.1 | GO:0051923 | purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) sulfation(GO:0051923) |
0.3 | 1.4 | GO:0007095 | blastocyst growth(GO:0001832) mitotic G2 DNA damage checkpoint(GO:0007095) |
0.3 | 0.8 | GO:0010430 | ethanol catabolic process(GO:0006068) fatty acid omega-oxidation(GO:0010430) |
0.3 | 0.8 | GO:0042097 | lymphotoxin A production(GO:0032641) interleukin-4 biosynthetic process(GO:0042097) lymphotoxin A biosynthetic process(GO:0042109) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404) |
0.3 | 0.8 | GO:0002752 | cell surface pattern recognition receptor signaling pathway(GO:0002752) |
0.3 | 1.4 | GO:0060164 | regulation of timing of neuron differentiation(GO:0060164) |
0.3 | 0.8 | GO:0048389 | intermediate mesoderm development(GO:0048389) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) bud dilation involved in lung branching(GO:0060503) branch elongation involved in ureteric bud branching(GO:0060681) regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) pulmonary artery morphogenesis(GO:0061156) cell proliferation involved in mesonephros development(GO:0061209) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) negative regulation of mesonephros development(GO:0061218) pattern specification involved in mesonephros development(GO:0061227) renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) BMP signaling pathway involved in nephric duct formation(GO:0071893) glomerular visceral epithelial cell development(GO:0072015) comma-shaped body morphogenesis(GO:0072049) regulation of branch elongation involved in ureteric bud branching(GO:0072095) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in kidney development(GO:0072098) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) glomerulus morphogenesis(GO:0072102) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104) mesenchymal cell proliferation involved in ureteric bud development(GO:0072138) nephric duct formation(GO:0072179) ureter urothelium development(GO:0072190) ureter epithelial cell differentiation(GO:0072192) ureter morphogenesis(GO:0072197) metanephric comma-shaped body morphogenesis(GO:0072278) glomerular epithelial cell development(GO:0072310) negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007) |
0.2 | 1.2 | GO:0007614 | short-term memory(GO:0007614) |
0.2 | 0.7 | GO:0043095 | regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105) |
0.2 | 5.6 | GO:0002504 | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504) |
0.2 | 0.9 | GO:0070527 | integrin activation(GO:0033622) regulation of integrin activation(GO:0033623) positive regulation of integrin activation(GO:0033625) platelet aggregation(GO:0070527) |
0.2 | 0.2 | GO:0010891 | negative regulation of lipid storage(GO:0010888) regulation of sequestering of triglyceride(GO:0010889) negative regulation of sequestering of triglyceride(GO:0010891) sequestering of triglyceride(GO:0030730) |
0.2 | 2.1 | GO:0046653 | tetrahydrofolate metabolic process(GO:0046653) |
0.2 | 1.0 | GO:0046642 | negative regulation of alpha-beta T cell proliferation(GO:0046642) |
0.2 | 0.8 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
0.2 | 2.7 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
0.2 | 0.2 | GO:0071460 | cellular response to cell-matrix adhesion(GO:0071460) |
0.2 | 2.5 | GO:0046697 | decidualization(GO:0046697) |
0.2 | 4.9 | GO:0051225 | spindle assembly(GO:0051225) |
0.2 | 2.7 | GO:0006071 | glycerol metabolic process(GO:0006071) |
0.2 | 0.6 | GO:0048619 | embryonic hindgut morphogenesis(GO:0048619) |
0.1 | 1.0 | GO:0006883 | cellular sodium ion homeostasis(GO:0006883) |
0.1 | 0.4 | GO:0010273 | regulation of oxidative phosphorylation(GO:0002082) detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169) |
0.1 | 0.4 | GO:0002538 | arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540) |
0.1 | 0.5 | GO:0010727 | negative regulation of hydrogen peroxide metabolic process(GO:0010727) |
0.1 | 0.4 | GO:0006982 | response to lipid hydroperoxide(GO:0006982) |
0.1 | 0.7 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) |
0.1 | 0.3 | GO:0010172 | embryonic body morphogenesis(GO:0010172) |
0.1 | 1.1 | GO:0048013 | ephrin receptor signaling pathway(GO:0048013) |
0.1 | 1.1 | GO:0006979 | response to oxidative stress(GO:0006979) |
0.1 | 1.1 | GO:0050858 | negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860) |
0.1 | 2.6 | GO:0033209 | tumor necrosis factor-mediated signaling pathway(GO:0033209) |
0.1 | 0.3 | GO:0008628 | hormone-mediated apoptotic signaling pathway(GO:0008628) |
0.1 | 1.1 | GO:0071345 | cellular response to cytokine stimulus(GO:0071345) |
0.1 | 0.4 | GO:0032959 | inositol trisphosphate biosynthetic process(GO:0032959) |
0.1 | 0.9 | GO:0042178 | xenobiotic catabolic process(GO:0042178) |
0.1 | 0.4 | GO:0050955 | thermoception(GO:0050955) |
0.1 | 0.9 | GO:0032515 | negative regulation of phosphoprotein phosphatase activity(GO:0032515) |
0.1 | 0.4 | GO:0006562 | proline catabolic process(GO:0006562) |
0.1 | 0.2 | GO:0006435 | threonyl-tRNA aminoacylation(GO:0006435) |
0.1 | 0.5 | GO:0016584 | nucleosome positioning(GO:0016584) |
0.1 | 1.2 | GO:0007342 | fusion of sperm to egg plasma membrane(GO:0007342) |
0.1 | 1.0 | GO:0051319 | mitotic G2 phase(GO:0000085) G2 phase(GO:0051319) |
0.1 | 0.7 | GO:0015074 | DNA integration(GO:0015074) |
0.1 | 0.5 | GO:0051383 | kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383) |
0.1 | 0.4 | GO:0061099 | negative regulation of protein tyrosine kinase activity(GO:0061099) |
0.1 | 0.2 | GO:0051971 | positive regulation of transmission of nerve impulse(GO:0051971) |
0.1 | 0.6 | GO:0007351 | tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595) |
0.1 | 0.3 | GO:0035444 | nickel cation transport(GO:0015675) vanadium ion transport(GO:0015676) ferrous iron transport(GO:0015684) lead ion transport(GO:0015692) nickel cation transmembrane transport(GO:0035444) ferrous iron import(GO:0070627) iron ion import(GO:0097286) |
0.1 | 0.8 | GO:0045087 | innate immune response(GO:0045087) |
0.1 | 0.2 | GO:0071436 | sodium ion export(GO:0071436) |
0.1 | 1.4 | GO:0008211 | glucocorticoid metabolic process(GO:0008211) |
0.1 | 0.3 | GO:0006515 | misfolded or incompletely synthesized protein catabolic process(GO:0006515) |
0.1 | 0.2 | GO:0051823 | hindbrain radial glia guided cell migration(GO:0021932) regulation of synapse structural plasticity(GO:0051823) |
0.1 | 0.5 | GO:0030299 | intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856) |
0.1 | 0.4 | GO:0051260 | protein homooligomerization(GO:0051260) |
0.0 | 0.2 | GO:0050857 | positive regulation of antigen receptor-mediated signaling pathway(GO:0050857) positive regulation of T cell receptor signaling pathway(GO:0050862) |
0.0 | 0.9 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
0.0 | 0.1 | GO:1904396 | regulation of synaptic growth at neuromuscular junction(GO:0008582) regulation of neuromuscular junction development(GO:1904396) |
0.0 | 1.6 | GO:0042475 | odontogenesis of dentin-containing tooth(GO:0042475) |
0.0 | 0.2 | GO:0042519 | tyrosine phosphorylation of Stat4 protein(GO:0042504) regulation of tyrosine phosphorylation of Stat4 protein(GO:0042519) positive regulation of tyrosine phosphorylation of Stat4 protein(GO:0042520) |
0.0 | 2.9 | GO:0019882 | antigen processing and presentation(GO:0019882) |
0.0 | 0.4 | GO:0007258 | JUN phosphorylation(GO:0007258) |
0.0 | 0.2 | GO:0006538 | glutamate catabolic process(GO:0006538) |
0.0 | 0.2 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
0.0 | 0.6 | GO:0060736 | prostate gland growth(GO:0060736) |
0.0 | 0.6 | GO:0090399 | replicative senescence(GO:0090399) |
0.0 | 2.2 | GO:0008206 | bile acid metabolic process(GO:0008206) |
0.0 | 0.2 | GO:0021759 | globus pallidus development(GO:0021759) menarche(GO:0042696) |
0.0 | 1.3 | GO:0009954 | proximal/distal pattern formation(GO:0009954) |
0.0 | 0.2 | GO:0000239 | pachytene(GO:0000239) |
0.0 | 0.4 | GO:0016998 | cell wall macromolecule catabolic process(GO:0016998) |
0.0 | 0.1 | GO:1901642 | purine nucleoside transmembrane transport(GO:0015860) purine-containing compound transmembrane transport(GO:0072530) nucleoside transmembrane transport(GO:1901642) |
0.0 | 0.8 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
0.0 | 0.3 | GO:0033089 | positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400) |
0.0 | 0.4 | GO:0009615 | response to virus(GO:0009615) |
0.0 | 0.5 | GO:0035024 | negative regulation of Rho protein signal transduction(GO:0035024) |
0.0 | 0.2 | GO:0001507 | acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581) |
0.0 | 0.3 | GO:0009750 | response to fructose(GO:0009750) |
0.0 | 0.5 | GO:0034332 | adherens junction organization(GO:0034332) |
0.0 | 0.1 | GO:0001692 | histamine metabolic process(GO:0001692) |
0.0 | 0.2 | GO:0021516 | dorsal spinal cord development(GO:0021516) |
0.0 | 0.3 | GO:0030147 | obsolete natriuresis(GO:0030147) |
0.0 | 1.0 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.0 | 0.4 | GO:0016601 | Rac protein signal transduction(GO:0016601) |
0.0 | 0.1 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
0.0 | 0.1 | GO:0006668 | sphinganine-1-phosphate metabolic process(GO:0006668) |
0.0 | 1.0 | GO:0060338 | regulation of type I interferon-mediated signaling pathway(GO:0060338) |
0.0 | 1.5 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
0.0 | 0.7 | GO:0071804 | cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805) |
0.0 | 2.3 | GO:0006096 | glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757) |
0.0 | 0.1 | GO:0048537 | mucosal-associated lymphoid tissue development(GO:0048537) |
0.0 | 2.5 | GO:0000236 | mitotic prometaphase(GO:0000236) |
0.0 | 0.4 | GO:0014046 | dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059) |
0.0 | 0.2 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
0.0 | 0.2 | GO:0009249 | protein lipoylation(GO:0009249) |
0.0 | 0.2 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
0.0 | 0.6 | GO:0051925 | obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925) |
0.0 | 0.0 | GO:0002331 | immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331) |
0.0 | 0.8 | GO:0046324 | regulation of glucose import(GO:0046324) |
0.0 | 1.6 | GO:0006959 | humoral immune response(GO:0006959) |
0.0 | 0.1 | GO:0009698 | phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804) |
0.0 | 0.7 | GO:0015758 | hexose transport(GO:0008645) glucose transport(GO:0015758) |
0.0 | 0.6 | GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154) |
0.0 | 0.3 | GO:0051568 | histone H3-K4 methylation(GO:0051568) |
0.0 | 0.3 | GO:0045749 | obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749) |
0.0 | 2.2 | GO:0008203 | cholesterol metabolic process(GO:0008203) |
0.0 | 0.9 | GO:0006694 | steroid biosynthetic process(GO:0006694) |
0.0 | 0.1 | GO:0060968 | regulation of gene silencing(GO:0060968) |
0.0 | 0.2 | GO:0071044 | histone mRNA catabolic process(GO:0071044) |
0.0 | 0.3 | GO:0048260 | positive regulation of receptor-mediated endocytosis(GO:0048260) |
0.0 | 0.6 | GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771) |
0.0 | 0.0 | GO:0016098 | monoterpenoid metabolic process(GO:0016098) |
0.0 | 0.4 | GO:0000060 | protein import into nucleus, translocation(GO:0000060) |
0.0 | 0.2 | GO:0045123 | cellular extravasation(GO:0045123) |
0.0 | 1.1 | GO:0031295 | lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295) |
0.0 | 0.1 | GO:1900087 | traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808) |
0.0 | 0.2 | GO:0090630 | activation of GTPase activity(GO:0090630) |
0.0 | 0.3 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
0.0 | 0.1 | GO:0043438 | acetoacetic acid metabolic process(GO:0043438) |
0.0 | 3.1 | GO:0097190 | apoptotic signaling pathway(GO:0097190) |
0.0 | 0.5 | GO:0043524 | negative regulation of neuron apoptotic process(GO:0043524) negative regulation of neuron death(GO:1901215) |
0.0 | 0.1 | GO:0006107 | oxaloacetate metabolic process(GO:0006107) |
0.0 | 0.2 | GO:0008334 | histone mRNA metabolic process(GO:0008334) |
0.0 | 2.0 | GO:0050658 | nucleic acid transport(GO:0050657) RNA transport(GO:0050658) establishment of RNA localization(GO:0051236) |
0.0 | 0.2 | GO:0015695 | organic cation transport(GO:0015695) |
0.0 | 0.3 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
0.0 | 0.1 | GO:0048535 | lymph node development(GO:0048535) |
0.0 | 0.2 | GO:0000291 | nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
0.0 | 0.2 | GO:0009395 | phospholipid catabolic process(GO:0009395) |
0.0 | 4.5 | GO:0051301 | cell division(GO:0051301) |
0.0 | 0.1 | GO:0050892 | intestinal absorption(GO:0050892) |
0.0 | 0.1 | GO:0006706 | steroid catabolic process(GO:0006706) |
0.0 | 0.3 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.0 | GO:0005726 | perichromatin fibrils(GO:0005726) |
0.5 | 4.9 | GO:0070652 | HAUS complex(GO:0070652) |
0.4 | 2.2 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
0.3 | 1.4 | GO:0042405 | nuclear inclusion body(GO:0042405) |
0.3 | 2.2 | GO:0046581 | intercellular canaliculus(GO:0046581) |
0.3 | 5.6 | GO:0042613 | MHC class II protein complex(GO:0042613) |
0.2 | 5.1 | GO:0042627 | chylomicron(GO:0042627) |
0.1 | 1.4 | GO:0034362 | low-density lipoprotein particle(GO:0034362) |
0.1 | 1.0 | GO:0000300 | obsolete peripheral to membrane of membrane fraction(GO:0000300) |
0.1 | 0.5 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453) |
0.1 | 0.5 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
0.1 | 2.9 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
0.1 | 2.8 | GO:0042612 | MHC class I protein complex(GO:0042612) |
0.1 | 0.6 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) beta-catenin-TCF complex(GO:1990907) |
0.1 | 1.6 | GO:0000783 | telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) |
0.1 | 0.3 | GO:0005686 | U2 snRNP(GO:0005686) |
0.1 | 0.8 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
0.1 | 0.9 | GO:0005577 | fibrinogen complex(GO:0005577) |
0.1 | 0.3 | GO:0016600 | flotillin complex(GO:0016600) |
0.1 | 0.9 | GO:0071778 | obsolete WINAC complex(GO:0071778) |
0.1 | 0.3 | GO:0070826 | paraferritin complex(GO:0070826) |
0.1 | 0.2 | GO:0072536 | interleukin-23 receptor complex(GO:0072536) |
0.1 | 0.4 | GO:0005811 | lipid particle(GO:0005811) |
0.0 | 0.1 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
0.0 | 0.7 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
0.0 | 0.6 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.0 | 1.0 | GO:0043205 | fibril(GO:0043205) |
0.0 | 0.4 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
0.0 | 0.8 | GO:0031105 | septin complex(GO:0031105) septin cytoskeleton(GO:0032156) |
0.0 | 0.2 | GO:0031305 | integral component of mitochondrial inner membrane(GO:0031305) |
0.0 | 0.2 | GO:0005683 | U7 snRNP(GO:0005683) |
0.0 | 0.1 | GO:0036452 | ESCRT III complex(GO:0000815) ESCRT complex(GO:0036452) |
0.0 | 0.3 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
0.0 | 1.4 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
0.0 | 0.3 | GO:0005828 | kinetochore microtubule(GO:0005828) |
0.0 | 0.1 | GO:0032584 | growth cone membrane(GO:0032584) |
0.0 | 0.1 | GO:0031436 | BRCA1-BARD1 complex(GO:0031436) |
0.0 | 0.4 | GO:0031528 | microvillus membrane(GO:0031528) |
0.0 | 0.2 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
0.0 | 1.3 | GO:0032587 | ruffle membrane(GO:0032587) |
0.0 | 0.4 | GO:0032982 | myosin filament(GO:0032982) |
0.0 | 0.6 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.0 | 0.5 | GO:0043034 | costamere(GO:0043034) |
0.0 | 0.4 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
0.0 | 0.5 | GO:0044665 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
0.0 | 0.4 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
0.0 | 1.6 | GO:0034705 | potassium channel complex(GO:0034705) |
0.0 | 0.6 | GO:0045095 | keratin filament(GO:0045095) |
0.0 | 0.2 | GO:0030315 | T-tubule(GO:0030315) |
0.0 | 0.7 | GO:0000781 | chromosome, telomeric region(GO:0000781) |
0.0 | 0.1 | GO:0005899 | insulin receptor complex(GO:0005899) |
0.0 | 0.1 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
0.0 | 0.2 | GO:0042101 | T cell receptor complex(GO:0042101) |
0.0 | 0.1 | GO:0060170 | ciliary membrane(GO:0060170) |
0.0 | 0.1 | GO:0045179 | apical cortex(GO:0045179) |
0.0 | 0.2 | GO:0005763 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
0.0 | 1.0 | GO:0034707 | chloride channel complex(GO:0034707) |
0.0 | 1.0 | GO:0005746 | mitochondrial respiratory chain(GO:0005746) |
0.0 | 0.7 | GO:0043197 | dendritic spine(GO:0043197) |
0.0 | 1.0 | GO:0031985 | Golgi cisterna(GO:0031985) |
0.0 | 0.0 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
0.0 | 1.6 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
0.0 | 1.1 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
0.0 | 0.6 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
0.0 | 0.7 | GO:0005643 | nuclear pore(GO:0005643) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 7.1 | GO:0047894 | flavonol 3-sulfotransferase activity(GO:0047894) |
0.7 | 2.8 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
0.7 | 4.8 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
0.6 | 2.9 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
0.5 | 2.6 | GO:0034711 | inhibin binding(GO:0034711) |
0.5 | 2.0 | GO:0042910 | xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910) |
0.4 | 1.7 | GO:0098847 | single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847) |
0.4 | 1.8 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
0.3 | 0.9 | GO:0004613 | phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613) |
0.3 | 0.8 | GO:0035276 | ethanol binding(GO:0035276) |
0.3 | 1.1 | GO:0008898 | S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898) |
0.3 | 2.2 | GO:0060228 | phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228) |
0.3 | 1.8 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
0.2 | 1.0 | GO:0047006 | 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) |
0.2 | 0.7 | GO:0044549 | GTP cyclohydrolase binding(GO:0044549) |
0.2 | 2.7 | GO:0034185 | apolipoprotein binding(GO:0034185) |
0.2 | 2.0 | GO:0034056 | estrogen response element binding(GO:0034056) |
0.2 | 1.2 | GO:0032190 | acrosin binding(GO:0032190) |
0.2 | 0.2 | GO:0047042 | androsterone dehydrogenase (B-specific) activity(GO:0047042) |
0.2 | 0.5 | GO:0050613 | delta14-sterol reductase activity(GO:0050613) |
0.2 | 0.9 | GO:0080030 | methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032) |
0.2 | 0.7 | GO:0008907 | integrase activity(GO:0008907) |
0.2 | 1.0 | GO:0019871 | sodium channel inhibitor activity(GO:0019871) |
0.2 | 1.1 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
0.2 | 1.0 | GO:0016647 | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647) |
0.1 | 1.0 | GO:0001846 | opsonin binding(GO:0001846) |
0.1 | 2.6 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) |
0.1 | 3.6 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
0.1 | 0.4 | GO:0031686 | A1 adenosine receptor binding(GO:0031686) |
0.1 | 1.5 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
0.1 | 0.5 | GO:0016531 | copper chaperone activity(GO:0016531) |
0.1 | 1.4 | GO:0015643 | toxic substance binding(GO:0015643) |
0.1 | 1.8 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
0.1 | 0.4 | GO:0070260 | 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260) |
0.1 | 0.5 | GO:0004083 | bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619) |
0.1 | 0.5 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
0.1 | 0.8 | GO:0001733 | galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694) |
0.1 | 0.4 | GO:0004657 | proline dehydrogenase activity(GO:0004657) |
0.1 | 0.6 | GO:0003960 | NADPH:quinone reductase activity(GO:0003960) |
0.1 | 0.8 | GO:0070700 | BMP receptor binding(GO:0070700) |
0.1 | 0.4 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
0.1 | 0.9 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
0.1 | 0.5 | GO:0008649 | rRNA methyltransferase activity(GO:0008649) |
0.1 | 0.3 | GO:0003951 | NAD+ kinase activity(GO:0003951) |
0.1 | 0.7 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
0.1 | 1.8 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
0.1 | 0.2 | GO:0004829 | threonine-tRNA ligase activity(GO:0004829) |
0.1 | 0.5 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
0.1 | 0.6 | GO:0017049 | GTP-Rho binding(GO:0017049) |
0.1 | 0.3 | GO:0017159 | pantetheine hydrolase activity(GO:0017159) |
0.1 | 1.5 | GO:0008430 | selenium binding(GO:0008430) |
0.1 | 0.3 | GO:0015087 | cobalt ion transmembrane transporter activity(GO:0015087) ferrous iron transmembrane transporter activity(GO:0015093) lead ion transmembrane transporter activity(GO:0015094) nickel cation transmembrane transporter activity(GO:0015099) vanadium ion transmembrane transporter activity(GO:0015100) chromium ion transmembrane transporter activity(GO:0070835) |
0.1 | 0.1 | GO:0047718 | indanol dehydrogenase activity(GO:0047718) |
0.1 | 0.4 | GO:0030492 | hemoglobin binding(GO:0030492) |
0.1 | 0.4 | GO:0008107 | galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127) |
0.1 | 1.2 | GO:0004467 | long-chain fatty acid-CoA ligase activity(GO:0004467) |
0.1 | 0.2 | GO:0042020 | interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020) |
0.1 | 0.4 | GO:0008158 | hedgehog receptor activity(GO:0008158) |
0.0 | 0.3 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
0.0 | 0.7 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
0.0 | 0.5 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
0.0 | 0.1 | GO:0008475 | procollagen-lysine 5-dioxygenase activity(GO:0008475) |
0.0 | 0.4 | GO:1901567 | icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567) |
0.0 | 0.1 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
0.0 | 1.8 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
0.0 | 0.7 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.0 | 0.5 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
0.0 | 0.5 | GO:0002162 | dystroglycan binding(GO:0002162) |
0.0 | 0.2 | GO:0004558 | alpha-1,4-glucosidase activity(GO:0004558) |
0.0 | 0.6 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
0.0 | 0.7 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
0.0 | 3.9 | GO:0008017 | microtubule binding(GO:0008017) |
0.0 | 0.6 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.0 | 0.4 | GO:0000175 | 3'-5'-exoribonuclease activity(GO:0000175) |
0.0 | 3.5 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.0 | 0.9 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
0.0 | 0.3 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
0.0 | 0.7 | GO:0030169 | low-density lipoprotein particle binding(GO:0030169) |
0.0 | 0.4 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
0.0 | 1.3 | GO:0050840 | extracellular matrix binding(GO:0050840) |
0.0 | 0.2 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
0.0 | 0.7 | GO:0000049 | tRNA binding(GO:0000049) |
0.0 | 0.7 | GO:0004697 | protein kinase C activity(GO:0004697) |
0.0 | 0.9 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.0 | 0.6 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
0.0 | 0.2 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
0.0 | 0.1 | GO:0005415 | nucleoside:sodium symporter activity(GO:0005415) |
0.0 | 0.8 | GO:0015026 | coreceptor activity(GO:0015026) |
0.0 | 0.6 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
0.0 | 1.4 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
0.0 | 1.0 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
0.0 | 0.3 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
0.0 | 2.8 | GO:0003704 | obsolete specific RNA polymerase II transcription factor activity(GO:0003704) |
0.0 | 0.4 | GO:0005522 | profilin binding(GO:0005522) |
0.0 | 0.2 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
0.0 | 0.1 | GO:0047023 | androsterone dehydrogenase activity(GO:0047023) |
0.0 | 0.3 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.0 | 1.4 | GO:0004221 | obsolete ubiquitin thiolesterase activity(GO:0004221) |
0.0 | 0.1 | GO:0017163 | obsolete basal transcription repressor activity(GO:0017163) |
0.0 | 0.4 | GO:0004889 | acetylcholine-activated cation-selective channel activity(GO:0004889) |
0.0 | 0.1 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
0.0 | 0.1 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
0.0 | 0.1 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
0.0 | 0.6 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.0 | 0.0 | GO:0004771 | sterol esterase activity(GO:0004771) |
0.0 | 0.1 | GO:0042392 | sphingosine-1-phosphate phosphatase activity(GO:0042392) |
0.0 | 0.6 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
0.0 | 0.5 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
0.0 | 0.7 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062) |
0.0 | 0.1 | GO:0003701 | obsolete RNA polymerase I transcription factor activity(GO:0003701) |
0.0 | 0.1 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
0.0 | 0.2 | GO:0015101 | organic cation transmembrane transporter activity(GO:0015101) |
0.0 | 0.3 | GO:0042826 | histone deacetylase binding(GO:0042826) |
0.0 | 0.3 | GO:0000146 | microfilament motor activity(GO:0000146) |
0.0 | 2.2 | GO:0010843 | obsolete promoter binding(GO:0010843) |
0.0 | 0.6 | GO:0008094 | DNA-dependent ATPase activity(GO:0008094) |
0.0 | 0.2 | GO:0003678 | DNA helicase activity(GO:0003678) |
0.0 | 1.2 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.0 | 3.6 | GO:0008134 | transcription factor binding(GO:0008134) |
0.0 | 0.6 | GO:0004177 | aminopeptidase activity(GO:0004177) |
0.0 | 0.2 | GO:0043531 | ADP binding(GO:0043531) |
0.0 | 0.2 | GO:0042605 | peptide antigen binding(GO:0042605) |
0.0 | 0.1 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.0 | 0.2 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
0.0 | 0.4 | GO:0008080 | N-acetyltransferase activity(GO:0008080) |
0.0 | 0.2 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.5 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
0.0 | 1.9 | SA_B_CELL_RECEPTOR_COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
0.0 | 0.9 | SA_PROGRAMMED_CELL_DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
0.0 | 2.0 | ST_P38_MAPK_PATHWAY | p38 MAPK Pathway |
0.0 | 1.2 | ST_INTERLEUKIN_4_PATHWAY | Interleukin 4 (IL-4) Pathway |
0.0 | 1.2 | SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
0.0 | 0.4 | ST_GRANULE_CELL_SURVIVAL_PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
0.0 | 1.2 | ST_T_CELL_SIGNAL_TRANSDUCTION | T Cell Signal Transduction |
0.0 | 0.4 | SA_CASPASE_CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
0.0 | 0.5 | ST_GAQ_PATHWAY | G alpha q Pathway |