Motif ID: DMBX1

Z-value: 0.693


Transcription factors associated with DMBX1:

Gene SymbolEntrez IDGene Name
DMBX1 ENSG00000197587.6 DMBX1



Activity profile for motif DMBX1.

activity profile for motif DMBX1


Sorted Z-values histogram for motif DMBX1

Sorted Z-values for motif DMBX1



Network of associatons between targets according to the STRING database.



First level regulatory network of DMBX1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_169552748 2.057 ENST00000504519.1
ENST00000512127.1
 PALLD

palladin, cytoskeletal associated protein

chr3_-_16524357 1.159 ENST00000432519.1
 RFTN1
raftlin, lipid raft linker 1
chr9_-_21995300 1.148 ENST00000498628.2
 CDKN2A
cyclin-dependent kinase inhibitor 2A
chr2_-_175711133 1.005 ENST00000409597.1
ENST00000413882.1
 CHN1

chimerin 1

chr6_+_89791507 0.968 ENST00000354922.3
 PNRC1
proline-rich nuclear receptor coactivator 1
chr9_-_21994344 0.940 ENST00000530628.2
ENST00000361570.3
 CDKN2A

cyclin-dependent kinase inhibitor 2A

chr12_+_53693812 0.935 ENST00000549488.1
 C12orf10
chromosome 12 open reading frame 10
chr9_-_21995249 0.885 ENST00000494262.1
 CDKN2A
cyclin-dependent kinase inhibitor 2A
chr9_-_21994597 0.778 ENST00000579755.1
 CDKN2A
cyclin-dependent kinase inhibitor 2A
chr3_-_121468513 0.749 ENST00000494517.1
ENST00000393667.3
 GOLGB1

golgin B1

chr3_-_121468602 0.679 ENST00000340645.5
 GOLGB1
golgin B1
chr19_+_41284121 0.678 ENST00000594800.1
ENST00000357052.2
ENST00000602173.1
 RAB4B


RAB4B, member RAS oncogene family


chrX_-_48931648 0.665 ENST00000376386.3
ENST00000376390.4
 PRAF2

PRA1 domain family, member 2

chr3_-_11685345 0.426 ENST00000430365.2
 VGLL4
vestigial like 4 (Drosophila)
chr15_-_85201779 0.339 ENST00000360476.3
ENST00000394588.3
 NMB

neuromedin B

chr2_+_223725652 0.337 ENST00000357430.3
ENST00000392066.3
 ACSL3

acyl-CoA synthetase long-chain family member 3

chr18_+_29027696 0.334 ENST00000257189.4
 DSG3
desmoglein 3
chr2_+_37571845 0.312 ENST00000537448.1
 QPCT
glutaminyl-peptide cyclotransferase
chr14_+_50234309 0.304 ENST00000298307.5
 KLHDC2
kelch domain containing 2
chr6_-_111927062 0.278 ENST00000359831.4
 TRAF3IP2
TRAF3 interacting protein 2
chr3_-_149293990 0.229 ENST00000472417.1
 WWTR1
WW domain containing transcription regulator 1
chr10_-_35104185 0.200 ENST00000374789.3
ENST00000374788.3
ENST00000346874.4
ENST00000374794.3
ENST00000350537.4
ENST00000374790.3
ENST00000374776.1
ENST00000374773.1
ENST00000545693.1
ENST00000545260.1
ENST00000340077.5
 PARD3










par-3 family cell polarity regulator










chr8_-_110656995 0.144 ENST00000276646.9
ENST00000533065.1
 SYBU

syntabulin (syntaxin-interacting)

chr10_+_74451883 0.130 ENST00000373053.3
ENST00000357157.6
 MCU

mitochondrial calcium uniporter

chr1_-_94586651 0.117 ENST00000535735.1
ENST00000370225.3
 ABCA4

ATP-binding cassette, sub-family A (ABC1), member 4

chr15_-_61521495 0.114 ENST00000335670.6
 RORA
RAR-related orphan receptor A
chr3_-_150920979 0.106 ENST00000309180.5
ENST00000480322.1
 GPR171

G protein-coupled receptor 171

chr12_+_54718904 0.091 ENST00000262061.2
ENST00000549043.1
ENST00000552218.1
ENST00000553231.1
ENST00000552362.1
ENST00000455864.2
ENST00000416254.2
ENST00000549116.1
ENST00000551779.1
 COPZ1








coatomer protein complex, subunit zeta 1








chr1_+_109756523 0.088 ENST00000234677.2
ENST00000369923.4
 SARS

seryl-tRNA synthetase

chr5_+_50678921 0.083 ENST00000230658.7
 ISL1
ISL LIM homeobox 1
chr3_-_149470229 0.080 ENST00000473414.1
 COMMD2
COMM domain containing 2
chr12_-_10959892 0.080 ENST00000240615.2
 TAS2R8
taste receptor, type 2, member 8
chr2_-_70780572 0.066 ENST00000450929.1
 TGFA
transforming growth factor, alpha
chr10_+_86004802 0.052 ENST00000359452.4
ENST00000358110.5
ENST00000372092.3
 RGR


retinal G protein coupled receptor


chr11_-_36619771 0.045 ENST00000311485.3
ENST00000527033.1
ENST00000532616.1
 RAG2


recombination activating gene 2


chr22_-_43411106 0.039 ENST00000453643.1
ENST00000263246.3
ENST00000337959.4
 PACSIN2


protein kinase C and casein kinase substrate in neurons 2


chr12_-_56727487 0.031 ENST00000548043.1
ENST00000425394.2
 PAN2

PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)

chr1_-_165414414 0.027 ENST00000359842.5
 RXRG
retinoid X receptor, gamma
chr3_+_138340067 0.027 ENST00000479848.1
 FAIM
Fas apoptotic inhibitory molecule
chr12_-_56727676 0.024 ENST00000547572.1
ENST00000257931.5
ENST00000440411.3
 PAN2


PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)


chr20_-_43729750 0.019 ENST00000537075.1
ENST00000306117.1
 KCNS1

potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1

chr12_-_103310987 0.005 ENST00000307000.2
 PAH
phenylalanine hydroxylase
chr17_-_12921270 0.002 ENST00000578071.1
ENST00000426905.3
ENST00000395962.2
ENST00000583371.1
ENST00000338034.4
 ELAC2




elaC ribonuclease Z 2




chr1_-_16563641 0.002 ENST00000375599.3
 RSG1
REM2 and RAB-like small GTPase 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.8 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
0.0 0.2 GO:0008356 asymmetric cell division(GO:0008356)
0.0 1.4 GO:0007030 Golgi organization(GO:0007030)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.7 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.3 GO:0035338 long-chain fatty-acyl-CoA metabolic process(GO:0035336) long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.0 GO:0002331 immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.1 GO:0005884 actin filament(GO:0005884)
0.0 1.4 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 3.8 GO:0016604 nuclear body(GO:0016604)
0.0 0.1 GO:0030126 COPI vesicle coat(GO:0030126)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.8 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.3 2.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.3 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.1 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.3 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.0 0.0 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.8 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.