Motif ID: E2F4

Z-value: 0.915


Transcription factors associated with E2F4:

Gene SymbolEntrez IDGene Name
E2F4 ENSG00000205250.4 E2F4



Activity profile for motif E2F4.

activity profile for motif E2F4


Sorted Z-values histogram for motif E2F4

Sorted Z-values for motif E2F4



Network of associatons between targets according to the STRING database.



First level regulatory network of E2F4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_135502408 1.272 ENST00000341911.5
ENST00000442647.2
ENST00000316528.8
MYB


v-myb avian myeloblastosis viral oncogene homolog


chr6_+_135502466 1.247 ENST00000367814.4
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr15_+_91260552 1.114 ENST00000355112.3
ENST00000560509.1
BLM

Bloom syndrome, RecQ helicase-like

chrX_+_109245863 1.063 ENST00000372072.3
TMEM164
transmembrane protein 164
chr8_+_48873453 1.040 ENST00000523944.1
MCM4
minichromosome maintenance complex component 4
chr8_+_48873479 1.040 ENST00000262105.2
MCM4
minichromosome maintenance complex component 4
chr1_+_91966384 1.007 ENST00000430031.2
ENST00000234626.6
CDC7

cell division cycle 7

chr22_+_19467261 0.974 ENST00000455750.1
ENST00000437685.2
ENST00000263201.1
ENST00000404724.3
CDC45



cell division cycle 45



chr15_+_51973680 0.969 ENST00000542355.2
SCG3
secretogranin III
chr15_+_51973550 0.957 ENST00000220478.3
SCG3
secretogranin III
chr1_+_91966656 0.951 ENST00000428239.1
ENST00000426137.1
CDC7

cell division cycle 7

chr7_-_99698338 0.933 ENST00000354230.3
ENST00000425308.1
MCM7

minichromosome maintenance complex component 7

chr4_-_73434498 0.927 ENST00000286657.4
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr1_-_26185844 0.907 ENST00000538789.1
ENST00000374298.3
AUNIP

aurora kinase A and ninein interacting protein

chr19_+_18284477 0.878 ENST00000407280.3
IFI30
interferon, gamma-inducible protein 30
chr2_+_172778952 0.874 ENST00000392584.1
ENST00000264108.4
HAT1

histone acetyltransferase 1

chr6_-_27114577 0.873 ENST00000356950.1
ENST00000396891.4
HIST1H2BK

histone cluster 1, H2bk

chr4_-_185655278 0.829 ENST00000281453.5
MLF1IP
centromere protein U
chr8_-_41754231 0.823 ENST00000265709.8
ANK1
ankyrin 1, erythrocytic
chr10_-_70231639 0.765 ENST00000551118.2
ENST00000358410.3
ENST00000399180.2
ENST00000399179.2
DNA2



DNA replication helicase/nuclease 2



chrX_+_109246285 0.759 ENST00000372073.1
ENST00000372068.2
ENST00000288381.4
TMEM164


transmembrane protein 164


chr14_-_55658323 0.757 ENST00000554067.1
ENST00000247191.2
DLGAP5

discs, large (Drosophila) homolog-associated protein 5

chr21_-_33651324 0.753 ENST00000290130.3
MIS18A
MIS18 kinetochore protein A
chr1_-_229761717 0.744 ENST00000366675.3
ENST00000258281.2
ENST00000366674.1
TAF5L


TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa


chr5_-_79950371 0.725 ENST00000511032.1
ENST00000504396.1
ENST00000505337.1
DHFR


dihydrofolate reductase


chr18_+_33767473 0.723 ENST00000261326.5
MOCOS
molybdenum cofactor sulfurase
chr1_-_145076186 0.719 ENST00000369348.3
PDE4DIP
phosphodiesterase 4D interacting protein
chr9_-_124991124 0.690 ENST00000394319.4
ENST00000340587.3
LHX6

LIM homeobox 6

chr1_-_28241024 0.689 ENST00000313433.7
ENST00000444045.1
RPA2

replication protein A2, 32kDa

chr19_-_49944806 0.688 ENST00000221485.3
SLC17A7
solute carrier family 17 (vesicular glutamate transporter), member 7
chr7_+_138145145 0.666 ENST00000415680.2
TRIM24
tripartite motif containing 24
chr19_+_50887585 0.663 ENST00000440232.2
ENST00000601098.1
ENST00000599857.1
ENST00000593887.1
POLD1



polymerase (DNA directed), delta 1, catalytic subunit



chr7_-_73668692 0.662 ENST00000352131.3
ENST00000055077.3
RFC2

replication factor C (activator 1) 2, 40kDa

chr2_+_48010312 0.638 ENST00000540021.1
MSH6
mutS homolog 6
chr8_-_95907423 0.638 ENST00000396133.3
ENST00000308108.4
CCNE2

cyclin E2

chr2_+_47630255 0.629 ENST00000406134.1
MSH2
mutS homolog 2
chr14_-_50154921 0.625 ENST00000553805.2
ENST00000554396.1
ENST00000216367.5
ENST00000539565.2
POLE2



polymerase (DNA directed), epsilon 2, accessory subunit



chr7_+_138145076 0.606 ENST00000343526.4
TRIM24
tripartite motif containing 24
chr2_+_47630108 0.597 ENST00000233146.2
ENST00000454849.1
ENST00000543555.1
MSH2


mutS homolog 2


chr15_+_48624300 0.593 ENST00000455976.2
ENST00000559540.1
DUT

deoxyuridine triphosphatase

chr21_-_44496441 0.587 ENST00000359624.3
ENST00000352178.5
CBS

cystathionine-beta-synthase

chr3_-_33759699 0.574 ENST00000399362.4
ENST00000359576.5
ENST00000307312.7
CLASP2


cytoplasmic linker associated protein 2


chr6_+_27100811 0.570 ENST00000359193.2
HIST1H2AG
histone cluster 1, H2ag
chr2_+_48010221 0.565 ENST00000234420.5
MSH6
mutS homolog 6
chr6_+_135502501 0.564 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB






v-myb avian myeloblastosis viral oncogene homolog






chr13_+_34392185 0.560 ENST00000380071.3
RFC3
replication factor C (activator 1) 3, 38kDa
chr1_+_173793641 0.560 ENST00000361951.4
DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr16_+_2510081 0.555 ENST00000361837.4
ENST00000569496.1
ENST00000567489.1
ENST00000563531.1
ENST00000483320.1
C16orf59




chromosome 16 open reading frame 59




chr1_+_63833261 0.554 ENST00000371108.4
ALG6
ALG6, alpha-1,3-glucosyltransferase
chr1_+_10490779 0.545 ENST00000477755.1
APITD1
apoptosis-inducing, TAF9-like domain 1
chr5_+_892745 0.542 ENST00000166345.3
TRIP13
thyroid hormone receptor interactor 13
chr11_-_118972575 0.539 ENST00000432443.2
DPAGT1
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr12_-_56843161 0.538 ENST00000554616.1
ENST00000553532.1
ENST00000229201.4
TIMELESS


timeless circadian clock


chr21_-_34915147 0.518 ENST00000381831.3
ENST00000381839.3
GART

phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase

chr1_+_28844648 0.518 ENST00000373832.1
ENST00000373831.3
RCC1

regulator of chromosome condensation 1

chr6_-_27100529 0.507 ENST00000607124.1
ENST00000339812.2
ENST00000541790.1
HIST1H2BJ


histone cluster 1, H2bj


chr15_-_50647274 0.502 ENST00000543881.1
GABPB1
GA binding protein transcription factor, beta subunit 1
chr3_-_33759541 0.501 ENST00000468888.2
CLASP2
cytoplasmic linker associated protein 2
chr1_+_28844778 0.493 ENST00000411533.1
RCC1
regulator of chromosome condensation 1
chr12_-_57146095 0.483 ENST00000550770.1
ENST00000338193.6
PRIM1

primase, DNA, polypeptide 1 (49kDa)

chr12_+_102514019 0.480 ENST00000537257.1
ENST00000358383.5
ENST00000392911.2
PARPBP


PARP1 binding protein


chr20_+_42295745 0.472 ENST00000396863.4
ENST00000217026.4
MYBL2

v-myb avian myeloblastosis viral oncogene homolog-like 2

chr4_-_1714037 0.469 ENST00000488267.1
ENST00000429429.2
ENST00000480936.1
SLBP


stem-loop binding protein


chr12_+_102513950 0.467 ENST00000378128.3
ENST00000327680.2
ENST00000541394.1
ENST00000543784.1
PARPBP



PARP1 binding protein



chr8_-_103136481 0.466 ENST00000524209.1
ENST00000517822.1
ENST00000523923.1
ENST00000521599.1
ENST00000521964.1
ENST00000311028.3
ENST00000518166.1
NCALD






neurocalcin delta






chr1_+_173793777 0.444 ENST00000239457.5
DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr1_-_197115818 0.442 ENST00000367409.4
ENST00000294732.7
ASPM

asp (abnormal spindle) homolog, microcephaly associated (Drosophila)

chr10_+_92631709 0.439 ENST00000413330.1
ENST00000277882.3
RPP30

ribonuclease P/MRP 30kDa subunit

chr10_-_43892279 0.435 ENST00000443950.2
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr2_+_68384976 0.430 ENST00000263657.2
PNO1
partner of NOB1 homolog (S. cerevisiae)
chr6_-_52149475 0.417 ENST00000419835.2
ENST00000229854.7
ENST00000596288.1
MCM3


minichromosome maintenance complex component 3


chr11_-_73694346 0.413 ENST00000310473.3
UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr4_-_1713977 0.412 ENST00000318386.4
SLBP
stem-loop binding protein
chr1_+_10490441 0.404 ENST00000309048.3
ENST00000470413.2
APITD1
APITD1-CORT
apoptosis-inducing, TAF9-like domain 1
APITD1-CORT readthrough
chr6_+_167412835 0.404 ENST00000349556.4
FGFR1OP
FGFR1 oncogene partner
chr1_+_27248203 0.395 ENST00000321265.5
NUDC
nudC nuclear distribution protein
chr3_-_148804275 0.391 ENST00000392912.2
ENST00000465259.1
ENST00000310053.5
ENST00000494055.1
HLTF



helicase-like transcription factor



chr15_-_50647370 0.385 ENST00000558970.1
ENST00000396464.3
ENST00000560825.1
GABPB1


GA binding protein transcription factor, beta subunit 1


chr17_-_76183111 0.380 ENST00000405273.1
ENST00000590862.1
ENST00000590430.1
ENST00000586613.1
TK1



thymidine kinase 1, soluble



chr16_-_67693846 0.375 ENST00000602850.1
ACD
adrenocortical dysplasia homolog (mouse)
chr7_+_100026406 0.374 ENST00000414441.1
MEPCE
methylphosphate capping enzyme
chr4_+_178230985 0.370 ENST00000264596.3
NEIL3
nei endonuclease VIII-like 3 (E. coli)
chr19_-_12912601 0.369 ENST00000334482.5
PRDX2
peroxiredoxin 2
chr8_+_128748308 0.367 ENST00000377970.2
MYC
v-myc avian myelocytomatosis viral oncogene homolog
chr17_-_34890759 0.365 ENST00000431794.3
MYO19
myosin XIX
chr1_-_241683001 0.363 ENST00000366560.3
FH
fumarate hydratase
chr8_+_128748466 0.361 ENST00000524013.1
ENST00000520751.1
MYC

v-myc avian myelocytomatosis viral oncogene homolog

chr10_-_43892668 0.358 ENST00000544000.1
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr19_-_6424783 0.357 ENST00000398148.3
KHSRP
KH-type splicing regulatory protein
chr11_+_32914579 0.350 ENST00000399302.2
QSER1
glutamine and serine rich 1
chr17_+_73106035 0.350 ENST00000581078.1
ENST00000582136.1
ENST00000245543.1
ARMC7


armadillo repeat containing 7


chr12_-_57472522 0.349 ENST00000379391.3
ENST00000300128.4
TMEM194A

transmembrane protein 194A

chr1_-_28241226 0.347 ENST00000373912.3
ENST00000373909.3
RPA2

replication protein A2, 32kDa

chr7_-_102985288 0.347 ENST00000379263.3
DNAJC2
DnaJ (Hsp40) homolog, subfamily C, member 2
chr2_+_10262857 0.343 ENST00000304567.5
RRM2
ribonucleotide reductase M2
chr11_+_58910201 0.342 ENST00000528737.1
FAM111A
family with sequence similarity 111, member A
chr7_-_129845188 0.339 ENST00000462753.1
ENST00000471077.1
ENST00000473456.1
ENST00000336804.8
TMEM209



transmembrane protein 209



chr9_-_124990680 0.334 ENST00000541397.2
ENST00000560485.1
LHX6

LIM homeobox 6

chr11_+_58910295 0.334 ENST00000420244.1
FAM111A
family with sequence similarity 111, member A
chr8_+_124084899 0.330 ENST00000287380.1
ENST00000309336.3
ENST00000519418.1
ENST00000327098.5
ENST00000522420.1
ENST00000521676.1
ENST00000378080.2
TBC1D31






TBC1 domain family, member 31






chr16_+_68119440 0.325 ENST00000346183.3
ENST00000329524.4
NFATC3

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3

chr22_-_42343117 0.325 ENST00000407253.3
ENST00000215980.5
CENPM

centromere protein M

chr15_+_89631647 0.323 ENST00000569550.1
ENST00000565066.1
ENST00000565973.1
ABHD2


abhydrolase domain containing 2


chr1_+_114472222 0.323 ENST00000369558.1
ENST00000369561.4
HIPK1

homeodomain interacting protein kinase 1

chr7_+_130794846 0.321 ENST00000421797.2
MKLN1
muskelin 1, intracellular mediator containing kelch motifs
chr16_+_29817399 0.321 ENST00000545521.1
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr22_-_42342692 0.315 ENST00000404067.1
ENST00000402338.1
CENPM

centromere protein M

chr19_-_12912657 0.312 ENST00000301522.2
PRDX2
peroxiredoxin 2
chr3_-_185655795 0.308 ENST00000342294.4
ENST00000382191.4
ENST00000453386.2
TRA2B


transformer 2 beta homolog (Drosophila)


chr6_+_167412665 0.304 ENST00000366847.4
FGFR1OP
FGFR1 oncogene partner
chr22_+_20105012 0.297 ENST00000331821.3
ENST00000411892.1
RANBP1

RAN binding protein 1

chr5_+_141348640 0.294 ENST00000540015.1
ENST00000506938.1
ENST00000394514.2
ENST00000512565.1
ENST00000394515.3
RNF14




ring finger protein 14




chr20_+_47662805 0.293 ENST00000262982.2
ENST00000542325.1
CSE1L

CSE1 chromosome segregation 1-like (yeast)

chr5_+_141348598 0.293 ENST00000394520.2
ENST00000347642.3
RNF14

ring finger protein 14

chr14_+_105219437 0.291 ENST00000329967.6
ENST00000347067.5
ENST00000553810.1
SIVA1


SIVA1, apoptosis-inducing factor


chr7_-_129845313 0.286 ENST00000397622.2
TMEM209
transmembrane protein 209
chr19_-_1095330 0.285 ENST00000586746.1
POLR2E
polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
chr17_+_5390220 0.281 ENST00000381165.3
MIS12
MIS12 kinetochore complex component
chr1_+_11333245 0.279 ENST00000376810.5
UBIAD1
UbiA prenyltransferase domain containing 1
chr6_+_30687978 0.277 ENST00000327892.8
ENST00000435534.1
TUBB

tubulin, beta class I

chr1_+_33116743 0.275 ENST00000414241.3
ENST00000373493.5
RBBP4

retinoblastoma binding protein 4

chr2_-_97535708 0.272 ENST00000305476.5
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr17_+_61678225 0.271 ENST00000258975.6
TACO1
translational activator of mitochondrially encoded cytochrome c oxidase I
chr1_-_33283754 0.268 ENST00000373477.4
YARS
tyrosyl-tRNA synthetase
chr9_-_77567743 0.267 ENST00000376854.5
C9orf40
chromosome 9 open reading frame 40
chr8_-_124408652 0.265 ENST00000287394.5
ATAD2
ATPase family, AAA domain containing 2
chr4_+_128802016 0.265 ENST00000270861.5
ENST00000515069.1
ENST00000513090.1
ENST00000507249.1
PLK4



polo-like kinase 4



chr7_-_44887620 0.265 ENST00000349299.3
ENST00000521529.1
ENST00000308153.4
ENST00000350771.3
ENST00000222690.6
ENST00000381124.5
ENST00000437072.1
ENST00000446531.1
H2AFV







H2A histone family, member V







chr7_+_116593433 0.265 ENST00000323984.3
ENST00000393449.1
ST7

suppression of tumorigenicity 7

chr19_-_48673580 0.264 ENST00000427526.2
LIG1
ligase I, DNA, ATP-dependent
chr17_-_41277467 0.261 ENST00000494123.1
ENST00000346315.3
ENST00000309486.4
ENST00000468300.1
ENST00000354071.3
ENST00000352993.3
ENST00000471181.2
BRCA1






breast cancer 1, early onset






chr14_-_71067360 0.258 ENST00000554963.1
ENST00000430055.2
ENST00000440435.2
ENST00000256379.5
MED6



mediator complex subunit 6



chr12_-_102513843 0.256 ENST00000551744.2
ENST00000552283.1
NUP37

nucleoporin 37kDa

chr15_+_40987327 0.256 ENST00000423169.2
ENST00000267868.3
ENST00000557850.1
ENST00000532743.1
ENST00000382643.3
RAD51




RAD51 recombinase




chr6_-_34855773 0.254 ENST00000420584.2
ENST00000361288.4
TAF11

TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa

chr6_+_57182400 0.252 ENST00000607273.1
PRIM2
primase, DNA, polypeptide 2 (58kDa)
chr11_+_110300607 0.252 ENST00000260270.2
FDX1
ferredoxin 1
chr1_+_114471972 0.251 ENST00000369559.4
ENST00000369554.2
HIPK1

homeodomain interacting protein kinase 1

chr10_-_62493223 0.249 ENST00000373827.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr11_+_34073195 0.248 ENST00000341394.4
CAPRIN1
cell cycle associated protein 1
chr5_+_177631523 0.248 ENST00000506339.1
ENST00000355836.5
ENST00000514633.1
ENST00000515193.1
ENST00000506259.1
ENST00000504898.1
HNRNPAB





heterogeneous nuclear ribonucleoprotein A/B





chr16_-_4401258 0.246 ENST00000577031.1
PAM16
presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr19_+_50180317 0.245 ENST00000534465.1
PRMT1
protein arginine methyltransferase 1
chr15_-_74988281 0.245 ENST00000566828.1
ENST00000563009.1
ENST00000568176.1
ENST00000566243.1
ENST00000566219.1
ENST00000426797.3
ENST00000566119.1
ENST00000315127.4
EDC3







enhancer of mRNA decapping 3







chr3_+_133502877 0.244 ENST00000466490.2
SRPRB
signal recognition particle receptor, B subunit
chr21_-_34100244 0.243 ENST00000382491.3
ENST00000357345.3
ENST00000429236.1
SYNJ1


synaptojanin 1


chr11_+_236540 0.239 ENST00000532097.1
PSMD13
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr5_+_141348721 0.239 ENST00000507163.1
ENST00000394519.1
RNF14

ring finger protein 14

chr17_+_60501228 0.237 ENST00000311506.5
METTL2A
methyltransferase like 2A
chr2_+_27440229 0.234 ENST00000264705.4
ENST00000403525.1
CAD

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

chr1_+_10092890 0.232 ENST00000253251.8
ENST00000377157.3
UBE4B

ubiquitination factor E4B

chr15_-_50647347 0.232 ENST00000220429.8
ENST00000429662.2
GABPB1

GA binding protein transcription factor, beta subunit 1

chr7_-_102985035 0.229 ENST00000426036.2
ENST00000249270.7
ENST00000454277.1
ENST00000412522.1
DNAJC2



DnaJ (Hsp40) homolog, subfamily C, member 2



chr20_-_35402123 0.227 ENST00000373740.3
ENST00000426836.1
ENST00000373745.3
ENST00000448110.2
ENST00000438549.1
ENST00000447406.1
ENST00000373750.4
ENST00000373734.4
DSN1







DSN1, MIS12 kinetochore complex component







chr12_+_49717019 0.226 ENST00000549275.1
ENST00000551245.1
ENST00000380327.5
ENST00000548311.1
ENST00000550346.1
ENST00000550709.1
ENST00000549534.1
ENST00000257909.3
TROAP







trophinin associated protein







chr4_+_39460620 0.224 ENST00000340169.2
ENST00000261434.3
LIAS

lipoic acid synthetase

chr16_-_67694129 0.224 ENST00000602320.1
ACD
adrenocortical dysplasia homolog (mouse)
chrX_+_129473916 0.221 ENST00000545805.1
ENST00000543953.1
ENST00000218197.5
SLC25A14


solute carrier family 25 (mitochondrial carrier, brain), member 14


chr4_+_39460659 0.220 ENST00000513731.1
LIAS
lipoic acid synthetase
chr12_+_5019061 0.220 ENST00000382545.3
KCNA1
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chr2_+_71357434 0.218 ENST00000244230.2
MPHOSPH10
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
chr17_-_41277370 0.218 ENST00000476777.1
ENST00000491747.2
ENST00000478531.1
ENST00000477152.1
ENST00000357654.3
ENST00000493795.1
ENST00000493919.1
BRCA1






breast cancer 1, early onset






chr11_-_72145426 0.217 ENST00000535990.1
ENST00000437826.2
ENST00000340729.5
CLPB


ClpB caseinolytic peptidase B homolog (E. coli)


chr11_-_119234876 0.213 ENST00000525735.1
USP2
ubiquitin specific peptidase 2
chr1_-_38019878 0.211 ENST00000296215.6
SNIP1
Smad nuclear interacting protein 1
chr11_+_85955787 0.211 ENST00000528180.1
EED
embryonic ectoderm development
chr3_+_160117418 0.208 ENST00000465903.1
ENST00000485645.1
ENST00000360111.2
ENST00000472991.1
ENST00000467468.1
ENST00000469762.1
ENST00000489573.1
ENST00000462787.1
ENST00000490207.1
ENST00000485867.1
SMC4









structural maintenance of chromosomes 4









chr21_-_34100341 0.207 ENST00000382499.2
ENST00000433931.2
SYNJ1

synaptojanin 1

chr21_+_47743995 0.206 ENST00000359568.5
PCNT
pericentrin
chr2_-_128785688 0.205 ENST00000259234.6
SAP130
Sin3A-associated protein, 130kDa
chr7_-_30544405 0.203 ENST00000409390.1
ENST00000409144.1
ENST00000005374.6
ENST00000409436.1
ENST00000275428.4
GGCT




gamma-glutamylcyclotransferase




chr7_-_152373216 0.203 ENST00000359321.1
XRCC2
X-ray repair complementing defective repair in Chinese hamster cells 2
chr11_+_34073269 0.203 ENST00000389645.3
CAPRIN1
cell cycle associated protein 1
chr3_-_10028366 0.203 ENST00000429759.1
EMC3
ER membrane protein complex subunit 3
chrX_-_20159934 0.201 ENST00000379593.1
ENST00000379607.5
EIF1AX

eukaryotic translation initiation factor 1A, X-linked

chr6_+_19837592 0.199 ENST00000378700.3
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr5_+_139781393 0.199 ENST00000360839.2
ENST00000297183.6
ENST00000421134.1
ENST00000394723.3
ENST00000511151.1
ANKHD1




ankyrin repeat and KH domain containing 1




chr9_+_131709966 0.199 ENST00000372577.2
NUP188
nucleoporin 188kDa
chr3_+_179280668 0.199 ENST00000429709.2
ENST00000450518.2
ENST00000392662.1
ENST00000490364.1
ACTL6A



actin-like 6A



chr11_+_237016 0.199 ENST00000352303.5
PSMD13
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr1_+_161129254 0.198 ENST00000368002.3
ENST00000289865.8
ENST00000479344.1
ENST00000368001.1
USP21



ubiquitin specific peptidase 21



chr1_-_55680762 0.198 ENST00000407756.1
ENST00000294383.6
USP24

ubiquitin specific peptidase 24

chr1_+_10490127 0.197 ENST00000602787.1
ENST00000602296.1
ENST00000400900.2
APITD1

APITD1-CORT
apoptosis-inducing, TAF9-like domain 1

APITD1-CORT readthrough
chr17_-_73781567 0.196 ENST00000586607.1
H3F3B
H3 histone, family 3B (H3.3B)
chr1_-_36615065 0.195 ENST00000373166.3
ENST00000373159.1
ENST00000373162.1
TRAPPC3


trafficking protein particle complex 3


chr4_+_39460689 0.193 ENST00000381846.1
LIAS
lipoic acid synthetase
chr5_+_149737202 0.192 ENST00000451292.1
ENST00000377797.3
ENST00000445265.2
ENST00000323668.7
ENST00000439160.2
ENST00000394269.3
ENST00000427724.2
ENST00000504761.2
ENST00000513346.1
ENST00000515516.1
TCOF1









Treacher Collins-Franceschetti syndrome 1









chr11_-_61734599 0.192 ENST00000532601.1
FTH1
ferritin, heavy polypeptide 1
chr11_-_123525289 0.190 ENST00000392770.2
ENST00000299333.3
ENST00000530277.1
SCN3B


sodium channel, voltage-gated, type III, beta subunit


chr19_-_48673552 0.190 ENST00000536218.1
ENST00000596549.1
LIG1

ligase I, DNA, ATP-dependent

chr2_+_157292933 0.189 ENST00000540309.1
GPD2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr6_+_27775899 0.189 ENST00000358739.3
HIST1H2AI
histone cluster 1, H2ai
chr5_-_43313574 0.189 ENST00000325110.6
ENST00000433297.2
HMGCS1

3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)

chr17_-_12921270 0.188 ENST00000578071.1
ENST00000426905.3
ENST00000395962.2
ENST00000583371.1
ENST00000338034.4
ELAC2




elaC ribonuclease Z 2




chr1_-_47779762 0.188 ENST00000371877.3
ENST00000360380.3
ENST00000337817.5
ENST00000447475.2
STIL



SCL/TAL1 interrupting locus



chr1_-_227505826 0.186 ENST00000334218.5
ENST00000366766.2
ENST00000366764.2
CDC42BPA


CDC42 binding protein kinase alpha (DMPK-like)


chr1_-_8939265 0.184 ENST00000489867.1
ENO1
enolase 1, (alpha)
chrX_-_100307043 0.182 ENST00000372939.1
ENST00000372935.1
ENST00000372936.3
TRMT2B


tRNA methyltransferase 2 homolog B (S. cerevisiae)


chr5_+_139493665 0.182 ENST00000331327.3
PURA
purine-rich element binding protein A
chrX_-_100307076 0.181 ENST00000338687.7
ENST00000545398.1
ENST00000372931.5
TRMT2B


tRNA methyltransferase 2 homolog B (S. cerevisiae)



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0006273 lagging strand elongation(GO:0006273)
0.4 1.3 GO:1901419 regulation of response to alcohol(GO:1901419)
0.4 1.1 GO:0031297 replication fork processing(GO:0031297)
0.4 0.7 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.3 2.5 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.3 0.9 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.3 3.4 GO:0033261 obsolete regulation of S phase(GO:0033261)
0.3 0.8 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079) chromosome movement towards spindle pole(GO:0051305)
0.2 0.7 GO:1904742 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381) regulation of telomeric DNA binding(GO:1904742) positive regulation of telomeric DNA binding(GO:1904744)
0.2 0.7 GO:1901724 positive regulation of cell proliferation involved in kidney development(GO:1901724)
0.2 0.6 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.2 0.6 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.2 0.6 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.2 0.8 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.2 7.2 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.2 0.6 GO:0046080 dUTP metabolic process(GO:0046080)
0.2 0.6 GO:0043418 cysteine biosynthetic process from serine(GO:0006535) homoserine metabolic process(GO:0009092) cysteine biosynthetic process via cystathionine(GO:0019343) transsulfuration(GO:0019346) homocysteine catabolic process(GO:0043418)
0.2 0.6 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.2 1.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.2 0.2 GO:0045005 DNA-dependent DNA replication maintenance of fidelity(GO:0045005) replication fork protection(GO:0048478)
0.1 0.4 GO:0016082 synaptic vesicle priming(GO:0016082)
0.1 0.4 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 1.0 GO:0021830 interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.1 0.5 GO:0019348 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.1 1.0 GO:0007090 obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.1 0.9 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.1 0.6 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.1 0.4 GO:0006106 fumarate metabolic process(GO:0006106)
0.1 0.5 GO:0007144 female meiosis I(GO:0007144)
0.1 0.5 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 1.8 GO:0034453 microtubule anchoring(GO:0034453)
0.1 0.5 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 0.3 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.1 0.3 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.1 0.4 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 0.7 GO:0043545 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.1 1.9 GO:0031055 DNA replication-independent nucleosome assembly(GO:0006336) chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) DNA replication-independent nucleosome organization(GO:0034724) CENP-A containing chromatin organization(GO:0061641)
0.1 0.7 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.7 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.1 0.4 GO:0051383 kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383)
0.1 0.2 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.1 0.2 GO:0035608 protein deglutamylation(GO:0035608)
0.1 0.2 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.1 0.2 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.3 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.0 1.1 GO:0000303 response to superoxide(GO:0000303)
0.0 0.2 GO:0009642 response to light intensity(GO:0009642) response to vitamin E(GO:0033197)
0.0 0.1 GO:0043173 purine nucleotide salvage(GO:0032261) nucleotide salvage(GO:0043173)
0.0 0.3 GO:0033504 floor plate development(GO:0033504)
0.0 0.8 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.8 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.2 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.4 GO:0007097 nuclear migration(GO:0007097)
0.0 0.9 GO:0030574 collagen catabolic process(GO:0030574)
0.0 2.3 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.1 GO:0090267 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.3 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.1 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.3 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.4 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.1 GO:0071168 protein localization to chromatin(GO:0071168)
0.0 0.2 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 0.1 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.6 GO:0006490 dolichol-linked oligosaccharide biosynthetic process(GO:0006488) oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 0.1 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.2 GO:0021895 cerebral cortex neuron differentiation(GO:0021895)
0.0 1.9 GO:0000236 mitotic prometaphase(GO:0000236)
0.0 0.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0 0.8 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.2 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.3 GO:0006386 transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0 0.2 GO:0006734 NADH metabolic process(GO:0006734)
0.0 0.1 GO:0045010 actin nucleation(GO:0045010)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.9 GO:0008033 tRNA processing(GO:0008033)
0.0 0.1 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 0.1 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.0 0.1 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.2 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.0 0.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.3 GO:0051225 spindle assembly(GO:0051225)
0.0 0.3 GO:0070304 positive regulation of stress-activated MAPK cascade(GO:0032874) positive regulation of stress-activated protein kinase signaling cascade(GO:0070304)
0.0 0.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.2 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.1 GO:0021513 spinal cord dorsal/ventral patterning(GO:0021513)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.2 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.3 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0032301 MutSalpha complex(GO:0032301)
0.4 1.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.3 1.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.3 3.4 GO:0042555 MCM complex(GO:0042555)
0.3 1.1 GO:0000800 lateral element(GO:0000800)
0.2 1.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.2 1.4 GO:0042575 DNA polymerase complex(GO:0042575)
0.2 0.6 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.2 1.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.7 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.6 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 0.9 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 1.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.8 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.1 GO:0032302 MutSbeta complex(GO:0032302)
0.1 0.7 GO:0060199 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.1 0.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.9 GO:0030914 STAGA complex(GO:0030914)
0.0 0.4 GO:0030681 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 0.7 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.6 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 2.2 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0001739 sex chromatin(GO:0001739)
0.0 0.4 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0 0.3 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 3.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.1 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.3 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.1 GO:0008278 cohesin complex(GO:0008278)
0.0 0.2 GO:0000796 condensin complex(GO:0000796)
0.0 1.1 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 1.7 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.0 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.3 GO:0097610 cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0032143 single thymine insertion binding(GO:0032143)
0.4 1.5 GO:0000405 bubble DNA binding(GO:0000405)
0.3 1.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.3 0.9 GO:0036002 pre-mRNA binding(GO:0036002)
0.3 1.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.3 0.8 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.2 0.7 GO:0003896 DNA primase activity(GO:0003896)
0.2 0.7 GO:0004146 dihydrofolate reductase activity(GO:0004146)
0.2 0.7 GO:0030151 molybdenum ion binding(GO:0030151)
0.2 0.6 GO:0070283 lipoate-protein ligase activity(GO:0016979) lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.2 0.6 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.2 0.6 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.2 1.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.2 1.1 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.1 1.3 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.7 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.5 GO:0016882 cyclo-ligase activity(GO:0016882)
0.1 0.4 GO:0004797 thymidine kinase activity(GO:0004797)
0.1 0.7 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.5 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.3 GO:0001618 virus receptor activity(GO:0001618)
0.1 0.7 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1 0.1 GO:0032357 single guanine insertion binding(GO:0032142) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.1 0.3 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 3.0 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 0.5 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 0.7 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.4 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.1 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187) glycine:sodium symporter activity(GO:0015375)
0.1 0.2 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.1 0.2 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.1 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.2 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.2 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.8 GO:0030507 spectrin binding(GO:0030507)
0.0 0.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.8 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 1.9 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.6 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.4 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.6 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.4 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.5 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.7 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 2.6 GO:0016566 obsolete specific transcriptional repressor activity(GO:0016566)
0.0 0.2 GO:0061659 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.2 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.4 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.1 GO:0031708 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 1.1 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.6 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.8 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.0 0.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.3 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922)
0.0 0.1 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.1 GO:0016563 obsolete transcription activator activity(GO:0016563)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.7 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway