Motif ID: E2F7_E2F1

Z-value: 4.208

Transcription factors associated with E2F7_E2F1:

Gene SymbolEntrez IDGene Name
E2F1 ENSG00000101412.9 E2F1
E2F7 ENSG00000165891.11 E2F7






Network of associatons between targets according to the STRING database.



First level regulatory network of E2F7_E2F1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_47630108 6.786 ENST00000233146.2
ENST00000454849.1
ENST00000543555.1
MSH2


mutS homolog 2


chr2_+_47630255 6.699 ENST00000406134.1
MSH2
mutS homolog 2
chr7_-_148581251 6.244 ENST00000478654.1
ENST00000460911.1
ENST00000350995.2
EZH2


enhancer of zeste homolog 2 (Drosophila)


chr5_+_126112794 5.875 ENST00000261366.5
ENST00000395354.1
LMNB1

lamin B1

chr22_+_23237555 5.671 ENST00000390321.2
IGLC1
immunoglobulin lambda constant 1 (Mcg marker)
chr18_+_29077990 5.570 ENST00000261590.8
DSG2
desmoglein 2
chr8_+_48873479 5.531 ENST00000262105.2
MCM4
minichromosome maintenance complex component 4
chr7_-_99698338 5.510 ENST00000354230.3
ENST00000425308.1
MCM7

minichromosome maintenance complex component 7

chr8_+_48873453 5.490 ENST00000523944.1
MCM4
minichromosome maintenance complex component 4
chr7_-_148581360 5.390 ENST00000320356.2
ENST00000541220.1
ENST00000483967.1
ENST00000536783.1
EZH2



enhancer of zeste homolog 2 (Drosophila)



chr11_-_19263145 5.077 ENST00000532666.1
ENST00000527884.1
E2F8

E2F transcription factor 8

chr19_-_48673580 5.057 ENST00000427526.2
LIG1
ligase I, DNA, ATP-dependent
chr7_-_99699538 4.757 ENST00000343023.6
ENST00000303887.5
MCM7

minichromosome maintenance complex component 7

chr1_+_91966384 4.705 ENST00000430031.2
ENST00000234626.6
CDC7

cell division cycle 7

chr11_-_93276582 4.696 ENST00000298966.2
SMCO4
single-pass membrane protein with coiled-coil domains 4
chr1_+_91966656 4.352 ENST00000428239.1
ENST00000426137.1
CDC7

cell division cycle 7

chr22_+_19467261 4.141 ENST00000455750.1
ENST00000437685.2
ENST00000263201.1
ENST00000404724.3
CDC45



cell division cycle 45



chr19_-_48673552 4.128 ENST00000536218.1
ENST00000596549.1
LIG1

ligase I, DNA, ATP-dependent

chr22_+_23243156 3.848 ENST00000390323.2
IGLC2
immunoglobulin lambda constant 2 (Kern-Oz- marker)
chr19_+_50887585 3.694 ENST00000440232.2
ENST00000601098.1
ENST00000599857.1
ENST00000593887.1
POLD1



polymerase (DNA directed), delta 1, catalytic subunit



chr12_-_57146095 3.570 ENST00000550770.1
ENST00000338193.6
PRIM1

primase, DNA, polypeptide 1 (49kDa)

chr7_+_116593568 3.550 ENST00000446490.1
ST7
suppression of tumorigenicity 7
chr16_-_85722530 3.530 ENST00000253462.3
GINS2
GINS complex subunit 2 (Psf2 homolog)
chr13_+_34392185 3.490 ENST00000380071.3
RFC3
replication factor C (activator 1) 3, 38kDa
chr17_+_5390220 3.479 ENST00000381165.3
MIS12
MIS12 kinetochore complex component
chr11_+_125496124 3.469 ENST00000533778.2
ENST00000534070.1
CHEK1

checkpoint kinase 1

chr1_-_52870104 3.407 ENST00000371568.3
ORC1
origin recognition complex, subunit 1
chr17_+_58677539 3.368 ENST00000305921.3
PPM1D
protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr7_-_158497431 3.365 ENST00000449727.2
ENST00000409339.3
ENST00000409423.1
ENST00000356309.3
NCAPG2



non-SMC condensin II complex, subunit G2



chr6_-_52149475 3.326 ENST00000419835.2
ENST00000229854.7
ENST00000596288.1
MCM3


minichromosome maintenance complex component 3


chr11_+_125495862 3.324 ENST00000428830.2
ENST00000544373.1
ENST00000527013.1
ENST00000526937.1
ENST00000534685.1
CHEK1




checkpoint kinase 1




chr4_-_174254823 3.306 ENST00000438704.2
HMGB2
high mobility group box 2
chr17_-_28618867 3.227 ENST00000394819.3
ENST00000577623.1
BLMH

bleomycin hydrolase

chr1_-_52870059 3.202 ENST00000371566.1
ORC1
origin recognition complex, subunit 1
chr22_+_35796056 3.169 ENST00000216122.4
MCM5
minichromosome maintenance complex component 5
chr7_+_116593433 3.169 ENST00000323984.3
ENST00000393449.1
ST7

suppression of tumorigenicity 7

chr17_-_28618948 3.092 ENST00000261714.6
BLMH
bleomycin hydrolase
chr11_-_73694346 3.044 ENST00000310473.3
UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr22_+_35796108 3.006 ENST00000382011.5
ENST00000416905.1
MCM5

minichromosome maintenance complex component 5

chr22_+_23248512 2.963 ENST00000390325.2
IGLC3
immunoglobulin lambda constant 3 (Kern-Oz+ marker)
chr7_-_129845188 2.852 ENST00000462753.1
ENST00000471077.1
ENST00000473456.1
ENST00000336804.8
TMEM209



transmembrane protein 209



chr3_+_157823609 2.831 ENST00000480820.1
RSRC1
arginine/serine-rich coiled-coil 1
chr21_-_34960930 2.796 ENST00000437395.1
DONSON
downstream neighbor of SON
chr15_+_51973680 2.791 ENST00000542355.2
SCG3
secretogranin III
chr17_+_30264014 2.790 ENST00000322652.5
ENST00000580398.1
SUZ12

SUZ12 polycomb repressive complex 2 subunit

chr15_+_51973550 2.787 ENST00000220478.3
SCG3
secretogranin III
chr21_-_34960948 2.782 ENST00000453626.1
ENST00000303113.6
ENST00000432378.1
ENST00000303071.5
DONSON



downstream neighbor of SON



chr6_+_391739 2.780 ENST00000380956.4
IRF4
interferon regulatory factor 4
chr11_+_4116005 2.749 ENST00000300738.5
RRM1
ribonucleotide reductase M1
chr17_-_76183111 2.726 ENST00000405273.1
ENST00000590862.1
ENST00000590430.1
ENST00000586613.1
TK1



thymidine kinase 1, soluble



chr12_-_56843161 2.649 ENST00000554616.1
ENST00000553532.1
ENST00000229201.4
TIMELESS


timeless circadian clock


chr6_-_97285336 2.644 ENST00000229955.3
ENST00000417980.1
GPR63

G protein-coupled receptor 63

chrX_+_8433376 2.620 ENST00000440654.2
ENST00000381029.4
VCX3B

variable charge, X-linked 3B

chr2_+_48010312 2.582 ENST00000540021.1
MSH6
mutS homolog 6
chr16_-_89007491 2.582 ENST00000327483.5
ENST00000564416.1
CBFA2T3

core-binding factor, runt domain, alpha subunit 2; translocated to, 3

chr5_+_61602055 2.575 ENST00000381103.2
KIF2A
kinesin heavy chain member 2A
chr15_-_65579177 2.575 ENST00000444347.2
ENST00000261888.6
PARP16

poly (ADP-ribose) polymerase family, member 16

chr6_+_13182751 2.572 ENST00000415087.1
PHACTR1
phosphatase and actin regulator 1
chr7_-_73668692 2.562 ENST00000352131.3
ENST00000055077.3
RFC2

replication factor C (activator 1) 2, 40kDa

chr2_+_27440229 2.557 ENST00000264705.4
ENST00000403525.1
CAD

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

chr3_-_53080047 2.529 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
SFMBT1



Scm-like with four mbt domains 1



chr16_-_23521710 2.507 ENST00000562117.1
ENST00000567468.1
ENST00000562944.1
ENST00000309859.4
GGA2



golgi-associated, gamma adaptin ear containing, ARF binding protein 2



chr20_+_61273797 2.503 ENST00000217159.1
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr8_-_95907423 2.490 ENST00000396133.3
ENST00000308108.4
CCNE2

cyclin E2

chr2_+_10262857 2.482 ENST00000304567.5
RRM2
ribonucleotide reductase M2
chr11_+_85955787 2.470 ENST00000528180.1
EED
embryonic ectoderm development
chr18_+_657733 2.428 ENST00000323250.5
ENST00000323224.7
TYMS

thymidylate synthetase

chr3_-_53079281 2.426 ENST00000394750.1
SFMBT1
Scm-like with four mbt domains 1
chr16_+_29817841 2.414 ENST00000322945.6
ENST00000562337.1
ENST00000566906.2
ENST00000563402.1
ENST00000219782.6
MAZ




MYC-associated zinc finger protein (purine-binding transcription factor)




chr2_+_48010221 2.397 ENST00000234420.5
MSH6
mutS homolog 6
chr9_+_106856831 2.367 ENST00000303219.8
ENST00000374787.3
SMC2

structural maintenance of chromosomes 2

chr14_-_38064198 2.359 ENST00000250448.2
FOXA1
forkhead box A1
chr10_-_43892668 2.347 ENST00000544000.1
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr12_+_4647950 2.316 ENST00000321524.7
ENST00000543041.1
ENST00000228843.9
ENST00000352618.4
ENST00000544927.1
RAD51AP1




RAD51 associated protein 1




chr1_-_28241024 2.313 ENST00000313433.7
ENST00000444045.1
RPA2

replication protein A2, 32kDa

chr11_+_4116054 2.308 ENST00000423050.2
RRM1
ribonucleotide reductase M1
chr21_+_35445827 2.283 ENST00000381151.3
ENST00000608209.1
SLC5A3
SLC5A3
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
sodium/myo-inositol cotransporter
chr5_-_79950371 2.265 ENST00000511032.1
ENST00000504396.1
ENST00000505337.1
DHFR


dihydrofolate reductase


chr16_-_74700737 2.255 ENST00000576652.1
ENST00000572337.1
ENST00000571750.1
ENST00000572990.1
ENST00000361070.4
RFWD3




ring finger and WD repeat domain 3




chr14_-_23426337 2.248 ENST00000342454.8
ENST00000555986.1
ENST00000541587.1
ENST00000554516.1
ENST00000347758.2
ENST00000206474.7
ENST00000555040.1
HAUS4






HAUS augmin-like complex, subunit 4






chr6_+_37137939 2.238 ENST00000373509.5
PIM1
pim-1 oncogene
chr8_-_124408652 2.226 ENST00000287394.5
ATAD2
ATPase family, AAA domain containing 2
chr8_+_128748308 2.226 ENST00000377970.2
MYC
v-myc avian myelocytomatosis viral oncogene homolog
chr1_-_47779762 2.224 ENST00000371877.3
ENST00000360380.3
ENST00000337817.5
ENST00000447475.2
STIL



SCL/TAL1 interrupting locus



chr3_-_148804275 2.221 ENST00000392912.2
ENST00000465259.1
ENST00000310053.5
ENST00000494055.1
HLTF



helicase-like transcription factor



chr14_-_23426322 2.206 ENST00000555367.1
HAUS4
HAUS augmin-like complex, subunit 4
chr14_-_23426270 2.203 ENST00000557591.1
ENST00000397409.4
ENST00000490506.1
ENST00000554406.1
HAUS4



HAUS augmin-like complex, subunit 4



chr16_+_29817399 2.192 ENST00000545521.1
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr22_+_19419425 2.185 ENST00000333130.3
MRPL40
mitochondrial ribosomal protein L40
chr19_-_6424783 2.167 ENST00000398148.3
KHSRP
KH-type splicing regulatory protein
chrX_+_48114752 2.158 ENST00000376919.3
SSX1
synovial sarcoma, X breakpoint 1
chr8_+_142402089 2.154 ENST00000521578.1
ENST00000520105.1
ENST00000523147.1
PTP4A3


protein tyrosine phosphatase type IVA, member 3


chr8_+_128748466 2.147 ENST00000524013.1
ENST00000520751.1
MYC

v-myc avian myelocytomatosis viral oncogene homolog

chr22_-_19419205 2.142 ENST00000340170.4
ENST00000263208.5
HIRA

histone cell cycle regulator

chr1_-_182360498 2.111 ENST00000417584.2
GLUL
glutamate-ammonia ligase
chr9_-_6645628 2.081 ENST00000321612.6
GLDC
glycine dehydrogenase (decarboxylating)
chr6_+_135502408 2.079 ENST00000341911.5
ENST00000442647.2
ENST00000316528.8
MYB


v-myb avian myeloblastosis viral oncogene homolog


chr2_+_172778952 2.075 ENST00000392584.1
ENST00000264108.4
HAT1

histone acetyltransferase 1

chr11_-_57194218 2.065 ENST00000529554.1
SLC43A3
solute carrier family 43, member 3
chr5_+_112312416 2.064 ENST00000389063.2
DCP2
decapping mRNA 2
chr10_+_105127704 2.053 ENST00000369839.3
ENST00000351396.4
TAF5

TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa

chr12_-_31479045 2.030 ENST00000539409.1
ENST00000395766.1
FAM60A

family with sequence similarity 60, member A

chr15_+_89787180 2.023 ENST00000300027.8
ENST00000310775.7
ENST00000567891.1
ENST00000564920.1
ENST00000565255.1
ENST00000567996.1
ENST00000451393.2
ENST00000563250.1
FANCI







Fanconi anemia, complementation group I







chr6_+_135502466 2.020 ENST00000367814.4
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr6_-_27799305 1.989 ENST00000357549.2
HIST1H4K
histone cluster 1, H4k
chr3_-_33759699 1.980 ENST00000399362.4
ENST00000359576.5
ENST00000307312.7
CLASP2


cytoplasmic linker associated protein 2


chr2_-_176032843 1.975 ENST00000392544.1
ENST00000409499.1
ENST00000426833.3
ENST00000392543.2
ENST00000538946.1
ENST00000487334.2
ENST00000409833.1
ENST00000409635.1
ENST00000264110.2
ENST00000345739.5
ATF2









activating transcription factor 2









chr20_+_57466629 1.973 ENST00000371081.1
ENST00000338783.6
GNAS

GNAS complex locus

chr4_-_174256276 1.961 ENST00000296503.5
HMGB2
high mobility group box 2
chr4_-_56502451 1.939 ENST00000511469.1
ENST00000264218.3
NMU

neuromedin U

chr3_-_186524234 1.933 ENST00000418288.1
ENST00000296273.2
RFC4

replication factor C (activator 1) 4, 37kDa

chr20_+_42295745 1.931 ENST00000396863.4
ENST00000217026.4
MYBL2

v-myb avian myeloblastosis viral oncogene homolog-like 2

chr16_+_68119247 1.920 ENST00000575270.1
NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr1_-_33502441 1.920 ENST00000548033.1
ENST00000487289.1
ENST00000373449.2
ENST00000480134.1
ENST00000467905.1
AK2




adenylate kinase 2




chr9_+_131451480 1.920 ENST00000322030.8
SET
SET nuclear oncogene
chr11_-_57103327 1.915 ENST00000529002.1
ENST00000278412.2
SSRP1

structure specific recognition protein 1

chr20_-_36661826 1.913 ENST00000373448.2
ENST00000373447.3
TTI1

TELO2 interacting protein 1

chrX_-_129244655 1.911 ENST00000335997.7
ELF4
E74-like factor 4 (ets domain transcription factor)
chrX_-_129244454 1.910 ENST00000308167.5
ELF4
E74-like factor 4 (ets domain transcription factor)
chr7_-_129845313 1.901 ENST00000397622.2
TMEM209
transmembrane protein 209
chr16_-_67693846 1.886 ENST00000602850.1
ACD
adrenocortical dysplasia homolog (mouse)
chr4_-_56502426 1.878 ENST00000505262.1
ENST00000507338.1
NMU

neuromedin U

chr2_+_170590321 1.874 ENST00000392647.2
KLHL23
kelch-like family member 23
chr3_+_186648307 1.872 ENST00000457772.2
ENST00000455441.1
ENST00000427315.1
ST6GAL1


ST6 beta-galactosamide alpha-2,6-sialyltranferase 1


chr22_+_20105012 1.867 ENST00000331821.3
ENST00000411892.1
RANBP1

RAN binding protein 1

chr3_+_186648274 1.841 ENST00000169298.3
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr9_+_106856541 1.839 ENST00000286398.7
ENST00000440179.1
ENST00000374793.3
SMC2


structural maintenance of chromosomes 2


chr1_+_46713404 1.831 ENST00000371975.4
ENST00000469835.1
RAD54L

RAD54-like (S. cerevisiae)

chr3_-_33759541 1.831 ENST00000468888.2
CLASP2
cytoplasmic linker associated protein 2
chr17_+_5389605 1.828 ENST00000576988.1
ENST00000576570.1
ENST00000573759.1
MIS12


MIS12 kinetochore complex component


chr14_-_91976488 1.826 ENST00000554684.1
ENST00000337238.4
ENST00000428424.2
ENST00000554511.1
SMEK1



SMEK homolog 1, suppressor of mek1 (Dictyostelium)



chr10_-_11653753 1.824 ENST00000609104.1
USP6NL
USP6 N-terminal like
chr1_-_33283754 1.823 ENST00000373477.4
YARS
tyrosyl-tRNA synthetase
chr1_-_25756638 1.816 ENST00000349320.3
RHCE
Rh blood group, CcEe antigens
chr6_+_161412759 1.815 ENST00000366919.2
ENST00000392142.4
ENST00000366920.2
ENST00000348824.7
MAP3K4



mitogen-activated protein kinase kinase kinase 4



chr3_+_53880588 1.810 ENST00000288167.3
ENST00000494338.1
IL17RB

interleukin 17 receptor B

chr12_-_48398104 1.802 ENST00000337299.6
ENST00000380518.3
COL2A1

collagen, type II, alpha 1

chr1_+_51434357 1.794 ENST00000396148.1
CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr11_-_57194550 1.793 ENST00000528187.1
ENST00000524863.1
ENST00000533051.1
ENST00000529494.1
ENST00000395124.1
ENST00000533524.1
ENST00000533245.1
ENST00000530316.1
SLC43A3







solute carrier family 43, member 3







chr4_-_77069533 1.791 ENST00000514987.1
ENST00000458189.2
ENST00000514901.1
ENST00000342467.6
NUP54



nucleoporin 54kDa



chr16_+_81040794 1.784 ENST00000439957.3
ENST00000393335.3
ENST00000428963.2
ENST00000564669.1
CENPN



centromere protein N



chr1_+_212208919 1.782 ENST00000366991.4
ENST00000542077.1
DTL

denticleless E3 ubiquitin protein ligase homolog (Drosophila)

chr3_+_128997798 1.782 ENST00000502878.2
ENST00000389735.3
ENST00000509551.1
ENST00000511665.1
HMCES



5-hydroxymethylcytosine (hmC) binding, ES cell-specific



chr17_-_42295870 1.781 ENST00000526094.1
ENST00000529383.1
ENST00000530828.1
UBTF


upstream binding transcription factor, RNA polymerase I


chr16_-_67694129 1.777 ENST00000602320.1
ACD
adrenocortical dysplasia homolog (mouse)
chr16_-_103572 1.767 ENST00000293860.5
POLR3K
polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
chr12_-_57472522 1.766 ENST00000379391.3
ENST00000300128.4
TMEM194A

transmembrane protein 194A

chr11_-_32457176 1.755 ENST00000332351.3
WT1
Wilms tumor 1
chr1_+_46713357 1.751 ENST00000442598.1
RAD54L
RAD54-like (S. cerevisiae)
chr12_+_96252706 1.751 ENST00000266735.5
ENST00000553192.1
ENST00000552085.1
SNRPF


small nuclear ribonucleoprotein polypeptide F


chr15_-_64673630 1.726 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101


KIAA0101


chrX_-_133119476 1.721 ENST00000543339.1
GPC3
glypican 3
chr16_+_31191431 1.716 ENST00000254108.7
ENST00000380244.3
ENST00000568685.1
FUS


fused in sarcoma


chr17_+_76165213 1.713 ENST00000590201.1
SYNGR2
synaptogyrin 2
chr6_+_30687978 1.708 ENST00000327892.8
ENST00000435534.1
TUBB

tubulin, beta class I

chr15_-_45670924 1.701 ENST00000396659.3
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr8_-_28243934 1.692 ENST00000521185.1
ENST00000520290.1
ENST00000344423.5
ZNF395


zinc finger protein 395


chr17_+_80416482 1.691 ENST00000309794.11
ENST00000345415.7
ENST00000457415.3
ENST00000584411.1
ENST00000412079.2
ENST00000577432.1
NARF





nuclear prelamin A recognition factor





chr1_+_89990431 1.689 ENST00000330947.2
ENST00000358200.4
LRRC8B

leucine rich repeat containing 8 family, member B

chr1_+_114472222 1.678 ENST00000369558.1
ENST00000369561.4
HIPK1

homeodomain interacting protein kinase 1

chr8_-_145642267 1.668 ENST00000301305.3
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr19_+_50432400 1.657 ENST00000423777.2
ENST00000600336.1
ENST00000597227.1
ATF5


activating transcription factor 5


chrX_-_133119895 1.656 ENST00000370818.3
GPC3
glypican 3
chr19_+_10765699 1.655 ENST00000590009.1
ILF3
interleukin enhancer binding factor 3, 90kDa
chr7_-_152373216 1.648 ENST00000359321.1
XRCC2
X-ray repair complementing defective repair in Chinese hamster cells 2
chr10_-_43892279 1.635 ENST00000443950.2
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr1_-_184943610 1.628 ENST00000367511.3
FAM129A
family with sequence similarity 129, member A
chr1_-_149832704 1.619 ENST00000392933.1
ENST00000369157.2
ENST00000392932.4
HIST2H4B


histone cluster 2, H4b


chr1_+_116915855 1.608 ENST00000295598.5
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr3_-_98312548 1.605 ENST00000264193.2
CPOX
coproporphyrinogen oxidase
chr5_-_79950775 1.595 ENST00000439211.2
DHFR
dihydrofolate reductase
chr2_-_208634287 1.594 ENST00000295417.3
FZD5
frizzled family receptor 5
chr5_+_43603229 1.591 ENST00000344920.4
ENST00000512996.2
NNT

nicotinamide nucleotide transhydrogenase

chr20_-_35724388 1.580 ENST00000344359.3
ENST00000373664.3
RBL1

retinoblastoma-like 1 (p107)

chr1_-_38273840 1.579 ENST00000373044.2
YRDC
yrdC N(6)-threonylcarbamoyltransferase domain containing
chr2_+_61108771 1.579 ENST00000394479.3
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr14_+_68086515 1.578 ENST00000261783.3
ARG2
arginase 2
chr8_+_21777159 1.570 ENST00000434536.1
ENST00000252512.9
XPO7

exportin 7

chr15_-_64673665 1.569 ENST00000300035.4
KIAA0101
KIAA0101
chrX_-_20159934 1.567 ENST00000379593.1
ENST00000379607.5
EIF1AX

eukaryotic translation initiation factor 1A, X-linked

chr4_-_77069573 1.560 ENST00000264883.3
NUP54
nucleoporin 54kDa
chr15_-_102029873 1.558 ENST00000348070.1
ENST00000358417.3
ENST00000344273.2
PCSK6


proprotein convertase subtilisin/kexin type 6


chr1_+_28844648 1.555 ENST00000373832.1
ENST00000373831.3
RCC1

regulator of chromosome condensation 1

chr12_+_56360550 1.552 ENST00000266970.4
CDK2
cyclin-dependent kinase 2
chr3_-_157823839 1.550 ENST00000425436.3
ENST00000389589.4
ENST00000441443.2
SHOX2


short stature homeobox 2


chr1_+_26798955 1.541 ENST00000361427.5
HMGN2
high mobility group nucleosomal binding domain 2
chr11_+_74303575 1.541 ENST00000263681.2
POLD3
polymerase (DNA-directed), delta 3, accessory subunit
chr3_+_52719936 1.539 ENST00000418458.1
ENST00000394799.2
GNL3

guanine nucleotide binding protein-like 3 (nucleolar)

chr1_+_179050512 1.530 ENST00000367627.3
TOR3A
torsin family 3, member A
chr16_+_28565230 1.529 ENST00000317058.3
CCDC101
coiled-coil domain containing 101
chr6_-_17706618 1.524 ENST00000262077.2
ENST00000537253.1
NUP153

nucleoporin 153kDa

chr6_-_29595779 1.515 ENST00000355973.3
ENST00000377012.4
GABBR1

gamma-aminobutyric acid (GABA) B receptor, 1

chr22_-_20104700 1.510 ENST00000439169.2
ENST00000445045.1
ENST00000404751.3
ENST00000252136.7
ENST00000403707.3
TRMT2A




tRNA methyltransferase 2 homolog A (S. cerevisiae)




chr6_-_27100529 1.504 ENST00000607124.1
ENST00000339812.2
ENST00000541790.1
HIST1H2BJ


histone cluster 1, H2bj


chr10_-_115614127 1.503 ENST00000369305.1
DCLRE1A
DNA cross-link repair 1A
chr17_+_76164639 1.491 ENST00000225777.3
ENST00000585591.1
ENST00000589711.1
ENST00000588282.1
ENST00000589168.1
SYNGR2




synaptogyrin 2




chr6_-_27114577 1.486 ENST00000356950.1
ENST00000396891.4
HIST1H2BK

histone cluster 1, H2bk

chr4_+_17812525 1.474 ENST00000251496.2
NCAPG
non-SMC condensin I complex, subunit G
chr2_-_58468437 1.463 ENST00000403676.1
ENST00000427708.2
ENST00000403295.3
ENST00000446381.1
ENST00000417361.1
ENST00000233741.4
ENST00000402135.3
ENST00000540646.1
ENST00000449070.1
FANCL








Fanconi anemia, complementation group L








chr6_-_90121938 1.452 ENST00000369415.4
RRAGD
Ras-related GTP binding D

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 13.5 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520) negative regulation of meiotic nuclear division(GO:0045835) regulation of meiosis I(GO:0060631)
1.9 75.3 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
1.7 6.8 GO:0071313 cellular response to caffeine(GO:0071313)
1.7 13.4 GO:0033261 obsolete regulation of S phase(GO:0033261)
1.5 4.6 GO:0019087 transformation of host cell by virus(GO:0019087)
1.5 4.4 GO:1904742 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381) regulation of telomeric DNA binding(GO:1904742) positive regulation of telomeric DNA binding(GO:1904744)
1.5 4.4 GO:0072216 positive regulation of metanephros development(GO:0072216) positive regulation of cell proliferation involved in kidney development(GO:1901724)
1.3 2.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
1.3 3.8 GO:0009648 photoperiodism(GO:0009648)
1.2 10.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
1.2 4.7 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
1.0 2.9 GO:0046600 negative regulation of centriole replication(GO:0046600)
1.0 4.8 GO:0032075 positive regulation of nuclease activity(GO:0032075)
1.0 5.7 GO:0000710 meiotic mismatch repair(GO:0000710)
0.9 2.8 GO:0042097 interleukin-4 biosynthetic process(GO:0042097) positive regulation of interleukin-10 biosynthetic process(GO:0045082) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.9 0.9 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.9 3.5 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.8 3.4 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.8 7.5 GO:0051290 protein heterotetramerization(GO:0051290)
0.8 4.0 GO:0050686 negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.8 3.1 GO:0019985 translesion synthesis(GO:0019985)
0.8 2.3 GO:0035608 protein deglutamylation(GO:0035608)
0.7 5.9 GO:0051383 kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383)
0.7 10.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.7 2.2 GO:0043366 beta selection(GO:0043366)
0.7 2.8 GO:0061032 visceral serous pericardium development(GO:0061032)
0.7 2.1 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.6 1.9 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.6 2.6 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.6 0.6 GO:0006066 alcohol metabolic process(GO:0006066)
0.6 0.6 GO:0009162 pyrimidine nucleoside monophosphate metabolic process(GO:0009129) deoxyribonucleoside monophosphate metabolic process(GO:0009162) pyrimidine deoxyribonucleoside monophosphate metabolic process(GO:0009176) dUMP metabolic process(GO:0046078)
0.6 3.1 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.6 1.8 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.6 12.7 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.5 1.6 GO:0060061 Spemann organizer formation(GO:0060061)
0.5 2.2 GO:0001575 globoside metabolic process(GO:0001575)
0.5 1.6 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.5 1.6 GO:0015809 arginine transport(GO:0015809)
0.5 2.6 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.5 2.5 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.5 2.5 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.5 3.0 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.5 2.8 GO:0007090 obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.5 1.4 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.5 1.4 GO:0016082 synaptic vesicle priming(GO:0016082)
0.5 1.4 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.4 1.3 GO:0046080 dUTP metabolic process(GO:0046080)
0.4 1.3 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.4 1.7 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.4 1.3 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.4 1.7 GO:0032898 neurotrophin production(GO:0032898)
0.4 1.3 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.4 1.7 GO:0042816 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.4 1.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.4 1.2 GO:0046732 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by virus of host immune response(GO:0075528)
0.4 0.8 GO:0035751 lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.4 2.7 GO:0033504 floor plate development(GO:0033504)
0.4 0.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.4 1.5 GO:0071168 protein localization to chromatin(GO:0071168)
0.4 3.8 GO:0001866 NK T cell proliferation(GO:0001866)
0.4 1.5 GO:0033602 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of dopamine secretion(GO:0033602)
0.4 1.1 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.4 1.1 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.4 1.1 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.4 1.1 GO:0046102 inosine metabolic process(GO:0046102)
0.4 1.1 GO:0061117 negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.4 5.9 GO:0007020 microtubule nucleation(GO:0007020)
0.4 1.1 GO:0003289 septum primum development(GO:0003284) atrial septum primum morphogenesis(GO:0003289)
0.4 1.4 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.4 0.7 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.3 3.1 GO:1900087 traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.3 8.4 GO:0051225 spindle assembly(GO:0051225)
0.3 1.0 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663) negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890) left/right pattern formation(GO:0060972)
0.3 1.3 GO:0060976 positive regulation of vascular wound healing(GO:0035470) coronary vasculature development(GO:0060976)
0.3 1.3 GO:0046671 regulation of nitrogen utilization(GO:0006808) positive regulation of neuron maturation(GO:0014042) nitrogen utilization(GO:0019740) cochlear nucleus development(GO:0021747) negative regulation of cellular pH reduction(GO:0032848) glial cell apoptotic process(GO:0034349) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671) positive regulation of cell maturation(GO:1903431)
0.3 2.2 GO:0031657 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.3 0.6 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.3 0.6 GO:0010834 obsolete telomere maintenance via telomere shortening(GO:0010834)
0.3 2.5 GO:1901985 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.3 2.9 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.3 1.2 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.3 1.5 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.3 3.9 GO:0030261 chromosome condensation(GO:0030261)
0.3 1.8 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.3 1.2 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.3 1.2 GO:0001705 ectoderm formation(GO:0001705)
0.3 0.9 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.3 1.2 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.3 1.7 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.3 2.6 GO:0006546 glycine catabolic process(GO:0006546)
0.3 0.8 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.3 2.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.3 0.8 GO:0031297 replication fork processing(GO:0031297)
0.3 2.2 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.3 1.6 GO:0034976 response to endoplasmic reticulum stress(GO:0034976)
0.3 0.5 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.3 0.8 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.3 1.9 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.3 0.8 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.3 1.8 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.3 1.0 GO:0016584 nucleosome positioning(GO:0016584)
0.2 1.7 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 3.6 GO:0006270 DNA replication initiation(GO:0006270)
0.2 1.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.2 2.2 GO:0043545 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.2 3.3 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.2 1.0 GO:0021830 interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.2 1.2 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.2 3.8 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.2 13.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 2.1 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.2 0.7 GO:0071280 epithelial fluid transport(GO:0042045) cellular response to copper ion(GO:0071280) cellular response to mercury ion(GO:0071288)
0.2 2.5 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.2 0.7 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.2 0.9 GO:0015917 aminophospholipid transport(GO:0015917)
0.2 1.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.2 7.3 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.2 5.0 GO:0034508 centromere complex assembly(GO:0034508)
0.2 0.9 GO:0060430 globus pallidus development(GO:0021759) menarche(GO:0042696) lung saccule development(GO:0060430) Clara cell differentiation(GO:0060486) Type II pneumocyte differentiation(GO:0060510)
0.2 0.6 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.2 3.4 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.2 1.0 GO:0001823 ureteric bud development(GO:0001657) mesonephros development(GO:0001823) mesonephric epithelium development(GO:0072163) mesonephric tubule development(GO:0072164)
0.2 0.8 GO:2000104 cell cycle DNA replication(GO:0044786) regulation of DNA-dependent DNA replication(GO:0090329) negative regulation of DNA-dependent DNA replication(GO:2000104)
0.2 0.4 GO:0039703 single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.2 0.8 GO:0006783 heme biosynthetic process(GO:0006783) heme metabolic process(GO:0042168) pigment biosynthetic process(GO:0046148)
0.2 1.8 GO:0043507 positive regulation of JUN kinase activity(GO:0043507)
0.2 1.2 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.2 0.6 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.2 0.6 GO:0051661 maintenance of centrosome location(GO:0051661)
0.2 1.4 GO:0016075 rRNA catabolic process(GO:0016075)
0.2 1.7 GO:0009249 protein lipoylation(GO:0009249)
0.2 0.7 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.2 0.9 GO:0032933 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.2 1.7 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.2 1.4 GO:0009113 purine nucleobase biosynthetic process(GO:0009113)
0.2 0.7 GO:0003057 regulation of the force of heart contraction by chemical signal(GO:0003057)
0.2 1.8 GO:0016180 snRNA processing(GO:0016180)
0.2 0.9 GO:0060999 positive regulation of dendritic spine development(GO:0060999) positive regulation of dendritic spine morphogenesis(GO:0061003)
0.2 3.7 GO:0007052 mitotic spindle organization(GO:0007052)
0.2 1.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.2 6.3 GO:0043484 regulation of RNA splicing(GO:0043484)
0.2 0.9 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.2 0.5 GO:0051026 chiasma assembly(GO:0051026)
0.2 1.4 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.2 1.9 GO:0006600 creatine metabolic process(GO:0006600)
0.2 0.5 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.2 0.7 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.2 0.2 GO:1901659 nucleoside biosynthetic process(GO:0009163) glycosyl compound biosynthetic process(GO:1901659)
0.2 1.8 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.2 1.6 GO:0016246 RNA interference(GO:0016246)
0.2 0.5 GO:0006106 fumarate metabolic process(GO:0006106)
0.2 3.7 GO:0000303 response to superoxide(GO:0000303)
0.2 0.8 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.2 1.3 GO:0048625 myoblast fate commitment(GO:0048625)
0.2 0.8 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.2 3.4 GO:0016574 histone ubiquitination(GO:0016574)
0.2 3.2 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.2 1.8 GO:0055069 cellular zinc ion homeostasis(GO:0006882) zinc ion homeostasis(GO:0055069)
0.2 8.7 GO:0006334 nucleosome assembly(GO:0006334)
0.2 0.5 GO:1901419 regulation of response to alcohol(GO:1901419)
0.2 0.3 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.2 1.1 GO:0046548 retinal rod cell development(GO:0046548)
0.1 2.5 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.1 3.7 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.4 GO:0016266 O-glycan processing(GO:0016266)
0.1 1.6 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 0.7 GO:0014820 tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.1 0.6 GO:0071459 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.1 1.0 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.1 1.2 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.1 2.6 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.1 0.8 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.4 GO:0031167 rRNA methylation(GO:0031167)
0.1 0.8 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.7 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 1.9 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 0.8 GO:0015871 choline transport(GO:0015871)
0.1 0.7 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 1.2 GO:0070189 kynurenine metabolic process(GO:0070189)
0.1 2.7 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.1 20.4 GO:0051028 mRNA transport(GO:0051028)
0.1 0.6 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 1.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 0.5 GO:0090267 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 0.5 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.1 0.3 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 0.7 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.1 2.1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 0.2 GO:0072205 collecting duct development(GO:0072044) metanephric collecting duct development(GO:0072205)
0.1 0.5 GO:0006006 glucose metabolic process(GO:0006006)
0.1 0.8 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 1.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.2 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.1 0.5 GO:0051319 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.1 0.2 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.1 0.6 GO:0001510 RNA methylation(GO:0001510)
0.1 1.2 GO:0006378 mRNA polyadenylation(GO:0006378)
0.1 0.7 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.1 3.7 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.1 0.6 GO:0001906 cell killing(GO:0001906)
0.1 0.6 GO:0006325 chromatin organization(GO:0006325)
0.1 0.7 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.2 GO:0033002 muscle cell proliferation(GO:0033002)
0.1 0.5 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 0.5 GO:0006839 mitochondrial transport(GO:0006839)
0.1 0.4 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.1 0.9 GO:0032355 response to estradiol(GO:0032355)
0.1 0.4 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.1 0.5 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.4 GO:0001942 hair follicle development(GO:0001942) molting cycle process(GO:0022404) hair cycle process(GO:0022405) molting cycle(GO:0042303) hair cycle(GO:0042633) skin epidermis development(GO:0098773)
0.1 0.3 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.1 1.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 1.6 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.1 0.3 GO:0071344 diphosphate metabolic process(GO:0071344)
0.1 0.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 1.3 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1 0.7 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 0.4 GO:0007097 nuclear migration(GO:0007097)
0.1 1.8 GO:0032011 ARF protein signal transduction(GO:0032011)
0.1 2.9 GO:0006284 base-excision repair(GO:0006284)
0.1 0.4 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.1 1.0 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.1 0.5 GO:0007035 vacuolar acidification(GO:0007035)
0.1 0.3 GO:0071848 regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) TNFSF11-mediated signaling pathway(GO:0071847) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.1 2.2 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.1 2.4 GO:0030851 granulocyte differentiation(GO:0030851)
0.1 1.2 GO:0014037 Schwann cell differentiation(GO:0014037)
0.1 0.4 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.1 0.3 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 0.7 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 0.2 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.1 0.9 GO:0016925 protein sumoylation(GO:0016925)
0.1 0.7 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 0.2 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.1 2.2 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.1 0.2 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.1 0.5 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.1 0.4 GO:0048550 negative regulation of pinocytosis(GO:0048550)
0.1 0.2 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 3.8 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.2 GO:0021779 oligodendrocyte cell fate commitment(GO:0021779)
0.1 1.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 1.3 GO:0032092 positive regulation of protein binding(GO:0032092)
0.1 2.0 GO:0030308 negative regulation of cell growth(GO:0030308)
0.1 0.9 GO:0001522 pseudouridine synthesis(GO:0001522)
0.1 0.8 GO:0007062 sister chromatid cohesion(GO:0007062)
0.1 1.4 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 0.1 GO:0036260 7-methylguanosine mRNA capping(GO:0006370) 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.1 1.2 GO:0008380 RNA splicing(GO:0008380)
0.1 0.3 GO:0000956 nuclear-transcribed mRNA catabolic process(GO:0000956)
0.1 0.2 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.4 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.1 1.3 GO:1903902 positive regulation of viral process(GO:0048524) positive regulation of viral transcription(GO:0050434) positive regulation of viral life cycle(GO:1903902)
0.1 0.5 GO:0060412 ventricular septum morphogenesis(GO:0060412)
0.1 0.7 GO:0032613 interleukin-10 production(GO:0032613)
0.1 0.9 GO:0006972 hyperosmotic response(GO:0006972)
0.1 0.8 GO:0044843 G1/S transition of mitotic cell cycle(GO:0000082) cell cycle G1/S phase transition(GO:0044843)
0.1 0.3 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.1 2.0 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 0.4 GO:0009128 AMP catabolic process(GO:0006196) nucleoside monophosphate catabolic process(GO:0009125) purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1 1.8 GO:0048709 oligodendrocyte differentiation(GO:0048709)
0.1 0.4 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.8 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.1 0.1 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.1 0.9 GO:0050812 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.1 4.0 GO:0006959 humoral immune response(GO:0006959)
0.1 0.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 0.4 GO:0007140 male meiosis(GO:0007140)
0.1 0.2 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 0.4 GO:0032464 regulation of protein homooligomerization(GO:0032462) positive regulation of protein homooligomerization(GO:0032464)
0.1 0.6 GO:0009404 toxin metabolic process(GO:0009404)
0.1 1.2 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 1.4 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.1 0.3 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.1 1.6 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.1 0.5 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 0.2 GO:0000239 pachytene(GO:0000239)
0.1 0.4 GO:0006477 protein sulfation(GO:0006477)
0.1 2.5 GO:0000236 mitotic prometaphase(GO:0000236)
0.1 0.3 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.1 1.4 GO:0006490 dolichol-linked oligosaccharide biosynthetic process(GO:0006488) oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.1 0.2 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.1 0.5 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.1 0.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.5 GO:0006213 pyrimidine nucleoside metabolic process(GO:0006213)
0.1 0.8 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.1 0.2 GO:0019919 pathogenesis(GO:0009405) peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 0.3 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015) inositol lipid-mediated signaling(GO:0048017)
0.1 0.4 GO:0001701 in utero embryonic development(GO:0001701)
0.1 0.6 GO:0006400 tRNA modification(GO:0006400)
0.1 1.1 GO:0030593 neutrophil chemotaxis(GO:0030593) neutrophil migration(GO:1990266)
0.1 0.6 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.1 0.4 GO:0001554 luteolysis(GO:0001554)
0.1 0.4 GO:0006298 mismatch repair(GO:0006298)
0.1 0.2 GO:0046697 decidualization(GO:0046697)
0.0 0.1 GO:0051053 negative regulation of DNA metabolic process(GO:0051053)
0.0 0.6 GO:0009607 response to biotic stimulus(GO:0009607)
0.0 0.2 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.1 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.8 GO:0001836 release of cytochrome c from mitochondria(GO:0001836)
0.0 0.4 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.2 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 1.1 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.7 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543) cellular response to fibroblast growth factor stimulus(GO:0044344) response to fibroblast growth factor(GO:0071774)
0.0 1.1 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 6.9 GO:0000375 RNA splicing, via transesterification reactions(GO:0000375)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 2.6 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 1.6 GO:0006289 nucleotide-excision repair(GO:0006289)
0.0 0.2 GO:0030578 nuclear body organization(GO:0030575) PML body organization(GO:0030578)
0.0 0.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.2 GO:0030238 male sex determination(GO:0030238)
0.0 0.1 GO:0010259 multicellular organism aging(GO:0010259)
0.0 0.2 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.9 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 5.4 GO:0006397 mRNA processing(GO:0006397)
0.0 0.1 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084) negative regulation of protein folding(GO:1903333)
0.0 0.5 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.0 GO:0060295 regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) cilium movement involved in cell motility(GO:0060294) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.1 GO:0051168 nuclear export(GO:0051168)
0.0 0.6 GO:0001502 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0 0.2 GO:0006405 RNA export from nucleus(GO:0006405)
0.0 0.3 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.4 GO:0042987 amyloid precursor protein catabolic process(GO:0042987)
0.0 0.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.6 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.2 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.8 GO:0006401 RNA catabolic process(GO:0006401)
0.0 0.2 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.5 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.4 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0 0.7 GO:0019835 cytolysis(GO:0019835)
0.0 0.2 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 1.3 GO:0008033 tRNA processing(GO:0008033)
0.0 0.2 GO:0015853 adenine transport(GO:0015853)
0.0 0.2 GO:0006547 histidine metabolic process(GO:0006547)
0.0 1.0 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.1 GO:0097061 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine development(GO:0060998) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.6 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.2 GO:0006541 glutamine metabolic process(GO:0006541)
0.0 0.2 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.8 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.4 GO:0051384 response to glucocorticoid(GO:0051384)
0.0 2.8 GO:0044819 mitotic G1 DNA damage checkpoint(GO:0031571) G1 DNA damage checkpoint(GO:0044783) mitotic G1/S transition checkpoint(GO:0044819)
0.0 0.2 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.7 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.2 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 1.5 GO:0006413 translational initiation(GO:0006413)
0.0 0.1 GO:0051958 methotrexate transport(GO:0051958)
0.0 0.2 GO:0042976 activation of Janus kinase activity(GO:0042976)
0.0 0.2 GO:0042493 response to drug(GO:0042493)
0.0 0.9 GO:0000272 polysaccharide catabolic process(GO:0000272)
0.0 0.3 GO:0031050 dsRNA fragmentation(GO:0031050) production of miRNAs involved in gene silencing by miRNA(GO:0035196) production of small RNA involved in gene silencing by RNA(GO:0070918)
0.0 0.3 GO:0061025 membrane fusion(GO:0061025)
0.0 0.1 GO:0051147 regulation of muscle cell differentiation(GO:0051147) positive regulation of muscle cell differentiation(GO:0051149)
0.0 0.3 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
0.0 0.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.3 GO:0045823 positive regulation of heart contraction(GO:0045823)
0.0 0.1 GO:0032229 negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.0 0.2 GO:0010165 response to X-ray(GO:0010165)
0.0 0.1 GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein(GO:0042517)
0.0 0.1 GO:0050666 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.0 0.6 GO:0018208 peptidyl-proline modification(GO:0018208)
0.0 1.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.2 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919) activation of cysteine-type endopeptidase activity(GO:0097202)
0.0 0.3 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.4 GO:0008633 obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0 1.4 GO:0034134 toll-like receptor 1 signaling pathway(GO:0034130) toll-like receptor 2 signaling pathway(GO:0034134)
0.0 0.5 GO:0007595 lactation(GO:0007595)
0.0 0.3 GO:0001662 behavioral fear response(GO:0001662)
0.0 0.5 GO:0016458 gene silencing(GO:0016458)
0.0 0.4 GO:0000279 M phase(GO:0000279)
0.0 0.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.7 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 1.2 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.1 GO:0009136 ADP biosynthetic process(GO:0006172) nucleoside diphosphate biosynthetic process(GO:0009133) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0 1.1 GO:0042593 carbohydrate homeostasis(GO:0033500) glucose homeostasis(GO:0042593)
0.0 3.4 GO:0006813 potassium ion transport(GO:0006813)
0.0 0.5 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.4 GO:0007215 glutamate receptor signaling pathway(GO:0007215)
0.0 0.3 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.3 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.4 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.4 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.4 GO:0007398 ectoderm development(GO:0007398)
0.0 1.5 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.3 GO:0015800 acidic amino acid transport(GO:0015800) L-glutamate transport(GO:0015813)
0.0 0.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.5 GO:0006302 double-strand break repair(GO:0006302)
0.0 0.7 GO:0006094 gluconeogenesis(GO:0006094)
0.0 0.2 GO:0019674 NAD metabolic process(GO:0019674)
0.0 0.5 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.6 GO:0043038 tRNA aminoacylation for protein translation(GO:0006418) amino acid activation(GO:0043038) tRNA aminoacylation(GO:0043039)
0.0 1.6 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.8 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 0.0 GO:0014887 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.2 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.2 GO:0051693 actin filament capping(GO:0051693)
0.0 0.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.6 GO:0006200 obsolete ATP catabolic process(GO:0006200)
0.0 0.4 GO:0051925 obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0 0.4 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.1 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.9 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.3 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.0 GO:0003321 positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0 0.2 GO:0042417 dopamine metabolic process(GO:0042417)
0.0 0.3 GO:0097193 intrinsic apoptotic signaling pathway(GO:0097193)
0.0 0.7 GO:0034339 obsolete regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor(GO:0034339)
0.0 1.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.1 GO:0045060 negative T cell selection(GO:0043383) negative thymic T cell selection(GO:0045060)
0.0 0.1 GO:0032097 adult feeding behavior(GO:0008343) positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 14.0 GO:0032302 MutSbeta complex(GO:0032302)
2.8 33.5 GO:0042555 MCM complex(GO:0042555)
2.5 5.0 GO:0032301 MutSalpha complex(GO:0032301)
1.4 9.8 GO:0005663 DNA replication factor C complex(GO:0005663)
1.4 19.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
1.1 5.5 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
1.1 4.4 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
1.1 5.3 GO:0000444 MIS12/MIND type complex(GO:0000444)
1.0 3.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
1.0 9.0 GO:0000796 condensin complex(GO:0000796)
1.0 2.9 GO:0000806 Y chromosome(GO:0000806)
0.9 2.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.9 0.9 GO:0001740 Barr body(GO:0001740)
0.9 7.2 GO:0042575 DNA polymerase complex(GO:0042575)
0.8 7.6 GO:0070652 HAUS complex(GO:0070652)
0.7 5.9 GO:0005638 lamin filament(GO:0005638)
0.6 2.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.6 6.6 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.6 4.6 GO:0030894 replisome(GO:0030894) nuclear replisome(GO:0043601)
0.5 2.7 GO:0030893 meiotic cohesin complex(GO:0030893)
0.4 4.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.4 1.2 GO:0005686 U2 snRNP(GO:0005686)
0.4 2.2 GO:0019815 immunoglobulin complex(GO:0019814) B cell receptor complex(GO:0019815)
0.4 1.1 GO:0031262 Ndc80 complex(GO:0031262)
0.3 6.6 GO:0005657 replication fork(GO:0005657)
0.3 1.0 GO:0035145 exon-exon junction complex(GO:0035145)
0.3 1.3 GO:0001940 male pronucleus(GO:0001940)
0.3 4.9 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.3 1.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.3 1.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.3 2.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.3 1.6 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.3 4.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.3 1.8 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.3 0.8 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.2 0.5 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.2 1.9 GO:0005683 U7 snRNP(GO:0005683)
0.2 3.1 GO:0030673 axolemma(GO:0030673)
0.2 2.6 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.2 1.9 GO:0042382 paraspeckles(GO:0042382)
0.2 1.2 GO:0005688 U6 snRNP(GO:0005688)
0.2 2.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.2 0.6 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.2 9.8 GO:0044815 DNA packaging complex(GO:0044815)
0.2 5.8 GO:0030057 desmosome(GO:0030057)
0.2 1.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 0.6 GO:0001652 granular component(GO:0001652)
0.2 2.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.2 1.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 2.0 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 1.0 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.2 1.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 2.5 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.2 7.9 GO:0005876 spindle microtubule(GO:0005876)
0.2 10.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.2 1.8 GO:0032039 integrator complex(GO:0032039)
0.2 0.8 GO:0005899 insulin receptor complex(GO:0005899)
0.2 0.6 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.2 0.5 GO:0033655 host(GO:0018995) host cell cytoplasm(GO:0030430) host cell part(GO:0033643) host intracellular part(GO:0033646) host cell cytoplasm part(GO:0033655) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.2 3.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 2.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.2 0.9 GO:0042584 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.1 0.3 GO:0060199 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.1 1.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.5 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 1.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.6 GO:0032300 mismatch repair complex(GO:0032300)
0.1 2.8 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.1 1.0 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 1.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.8 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 1.6 GO:0005838 proteasome regulatory particle(GO:0005838)
0.1 0.6 GO:0001739 sex chromatin(GO:0001739)
0.1 4.5 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.1 1.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 0.7 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 0.7 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 4.9 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.1 1.3 GO:1903561 extracellular organelle(GO:0043230) extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.1 0.8 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.1 15.7 GO:0016607 nuclear speck(GO:0016607)
0.1 3.5 GO:0000790 nuclear chromatin(GO:0000790)
0.1 1.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 1.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 5.6 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 0.3 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.1 0.2 GO:0000792 heterochromatin(GO:0000792)
0.1 2.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 9.1 GO:0005643 nuclear pore(GO:0005643)
0.1 2.4 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 0.6 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.8 GO:0045211 postsynaptic membrane(GO:0045211) postsynapse(GO:0098794)
0.1 7.1 GO:0016605 PML body(GO:0016605)
0.1 0.4 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.2 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 5.9 GO:0016363 nuclear matrix(GO:0016363)
0.1 2.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 0.3 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.4 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 5.5 GO:0000793 condensed chromosome(GO:0000793)
0.1 1.4 GO:0000178 exosome (RNase complex)(GO:0000178)
0.1 2.2 GO:0016592 mediator complex(GO:0016592)
0.1 4.3 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.1 0.5 GO:0031519 PcG protein complex(GO:0031519)
0.1 2.3 GO:0005796 Golgi lumen(GO:0005796)
0.1 1.0 GO:0031143 pseudopodium(GO:0031143)
0.1 5.8 GO:1990204 oxidoreductase complex(GO:1990204)
0.1 0.9 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.3 GO:0032993 protein-DNA complex(GO:0032993)
0.1 0.4 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 2.9 GO:0019717 obsolete synaptosome(GO:0019717)
0.1 0.5 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 0.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 0.8 GO:0031941 filamentous actin(GO:0031941)
0.1 1.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.8 GO:0043034 costamere(GO:0043034)
0.1 0.5 GO:0014704 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.1 0.5 GO:0030686 90S preribosome(GO:0030686)
0.1 19.0 GO:0005667 transcription factor complex(GO:0005667)
0.1 1.3 GO:0071564 npBAF complex(GO:0071564)
0.1 0.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 5.2 GO:0030141 secretory granule(GO:0030141)
0.1 0.7 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.1 0.1 GO:0042597 outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0 1.3 GO:0043209 myelin sheath(GO:0043209)
0.0 0.6 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 3.7 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.8 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.8 GO:0043198 dendritic shaft(GO:0043198)
0.0 2.6 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.0 0.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 1.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 9.5 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 32.3 GO:0005654 nucleoplasm(GO:0005654)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 30.2 GO:0005730 nucleolus(GO:0005730)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.4 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.7 GO:0005861 troponin complex(GO:0005861)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 1.6 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.8 GO:0005605 basal lamina(GO:0005605)
0.0 0.6 GO:1990904 intracellular ribonucleoprotein complex(GO:0030529) ribonucleoprotein complex(GO:1990904)
0.0 1.2 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.3 GO:0043202 lysosomal lumen(GO:0043202)
0.0 1.9 GO:0016459 myosin complex(GO:0016459)
0.0 0.7 GO:0043197 dendritic spine(GO:0043197)
0.0 0.3 GO:0005884 actin filament(GO:0005884)
0.0 1.2 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 2.3 GO:0005840 ribosome(GO:0005840)
0.0 0.2 GO:0046930 pore complex(GO:0046930)
0.0 0.6 GO:0000922 spindle pole(GO:0000922)
0.0 1.6 GO:0005694 chromosome(GO:0005694)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 1.7 GO:0005769 early endosome(GO:0005769)
0.0 0.3 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.4 GO:0005902 microvillus(GO:0005902)
0.0 0.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.4 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 40.9 GO:0005634 nucleus(GO:0005634)
0.0 0.4 GO:0030496 midbody(GO:0030496)
0.0 0.2 GO:0030175 filopodium(GO:0030175)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 14.0 GO:0000404 heteroduplex DNA loop binding(GO:0000404) double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
2.5 5.0 GO:0032357 single guanine insertion binding(GO:0032142) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
1.9 7.5 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
1.8 9.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
1.8 5.5 GO:0003896 DNA primase activity(GO:0003896)
1.6 9.7 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
1.3 3.9 GO:0004146 dihydrofolate reductase activity(GO:0004146)
1.2 3.7 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
1.2 4.7 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.9 1.9 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.9 2.7 GO:0004797 thymidine kinase activity(GO:0004797)
0.9 3.5 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.8 5.6 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.8 6.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.7 4.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.6 1.8 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.6 23.0 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.5 3.8 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.5 2.2 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.5 1.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.5 1.5 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.5 2.0 GO:0004074 biliverdin reductase activity(GO:0004074)
0.5 2.0 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.5 1.4 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.5 1.8 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.4 1.3 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.4 1.3 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.4 1.7 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.4 1.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.4 0.8 GO:0016362 activin receptor activity, type II(GO:0016362)
0.4 1.2 GO:0036002 pre-mRNA binding(GO:0036002)
0.4 2.7 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.4 1.5 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.4 2.6 GO:0042978 ornithine decarboxylase inhibitor activity(GO:0008073) ornithine decarboxylase activator activity(GO:0042978)
0.4 1.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.4 3.0 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.4 2.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.4 5.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.4 9.1 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.4 5.4 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.4 18.9 GO:0042054 histone methyltransferase activity(GO:0042054)
0.3 1.0 GO:0030151 molybdenum ion binding(GO:0030151)
0.3 1.4 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.3 1.4 GO:0003951 NAD+ kinase activity(GO:0003951)
0.3 1.0 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.3 1.3 GO:0002060 purine nucleobase binding(GO:0002060)
0.3 1.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.3 1.0 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.3 0.6 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.3 2.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.3 2.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.3 0.3 GO:0001618 virus receptor activity(GO:0001618)
0.3 2.5 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.3 0.9 GO:0015247 aminophospholipid transporter activity(GO:0015247)
0.3 1.8 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.3 1.2 GO:0070548 1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847) L-glutamine aminotransferase activity(GO:0070548)
0.3 1.2 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.3 1.7 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.3 1.2 GO:0043398 HLH domain binding(GO:0043398)
0.3 0.8 GO:0050692 DBD domain binding(GO:0050692)
0.3 0.8 GO:0016731 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.3 3.4 GO:0016896 exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.3 2.6 GO:0003701 obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.3 2.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.3 2.0 GO:0050733 RS domain binding(GO:0050733)
0.2 1.0 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.2 0.7 GO:0031755 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.2 1.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.2 3.3 GO:0035173 histone kinase activity(GO:0035173)
0.2 1.4 GO:0016564 obsolete transcription repressor activity(GO:0016564)
0.2 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.2 6.2 GO:0035064 methylated histone binding(GO:0035064)
0.2 0.7 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.2 0.9 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.2 13.0 GO:0003823 antigen binding(GO:0003823)
0.2 0.9 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.2 2.4 GO:0061659 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.2 0.6 GO:0030621 U4 snRNA binding(GO:0030621)
0.2 1.9 GO:0030544 Hsp70 protein binding(GO:0030544)
0.2 3.9 GO:0005542 folic acid binding(GO:0005542)
0.2 1.2 GO:0002039 p53 binding(GO:0002039)
0.2 1.9 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.2 0.6 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.2 1.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.2 0.8 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.2 1.0 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.2 2.3 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.2 4.6 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 1.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 2.4 GO:0016918 retinal binding(GO:0016918)
0.2 2.8 GO:0004017 adenylate kinase activity(GO:0004017)
0.2 0.7 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.2 1.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 0.4 GO:0001849 complement component C1q binding(GO:0001849)
0.2 0.5 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.2 1.0 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.2 4.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.2 9.0 GO:0004180 carboxypeptidase activity(GO:0004180)
0.2 3.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.2 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 2.6 GO:0017025 TBP-class protein binding(GO:0017025)
0.2 1.0 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 0.5 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.2 0.5 GO:0015217 purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) ATP:ADP antiporter activity(GO:0005471) ADP transmembrane transporter activity(GO:0015217)
0.2 0.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2 0.5 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2 1.2 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.2 0.5 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 0.6 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.1 0.4 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 2.5 GO:0030507 spectrin binding(GO:0030507)
0.1 2.4 GO:0005521 lamin binding(GO:0005521)
0.1 1.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.7 GO:0051434 BH3 domain binding(GO:0051434)
0.1 6.0 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 4.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 3.0 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 0.4 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.1 1.9 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 0.5 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.1 0.4 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.1 1.6 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 0.7 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 0.8 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.1 0.3 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 0.7 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 1.0 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 0.6 GO:0034061 DNA polymerase activity(GO:0034061)
0.1 0.1 GO:0032564 dATP binding(GO:0032564)
0.1 3.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.9 GO:0016151 nickel cation binding(GO:0016151)
0.1 0.6 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.1 13.7 GO:0016566 obsolete specific transcriptional repressor activity(GO:0016566)
0.1 0.5 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 1.6 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 1.8 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 3.7 GO:0004527 exonuclease activity(GO:0004527)
0.1 0.7 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 3.8 GO:0003684 damaged DNA binding(GO:0003684)
0.1 0.3 GO:0017130 poly(C) RNA binding(GO:0017130)
0.1 5.9 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 1.9 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.1 0.6 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 2.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.8 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 0.5 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 2.3 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.1 1.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.1 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 4.9 GO:0042393 histone binding(GO:0042393)
0.1 0.7 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.6 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 0.4 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1 0.3 GO:0043199 sulfate binding(GO:0043199)
0.1 2.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.4 GO:0004335 galactokinase activity(GO:0004335)
0.1 0.9 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 0.4 GO:0032810 sterol response element binding(GO:0032810)
0.1 2.2 GO:0030528 obsolete transcription regulator activity(GO:0030528)
0.1 1.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.0 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 1.3 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.1 1.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 1.1 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.1 0.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.7 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.4 GO:0019213 deacetylase activity(GO:0019213)
0.1 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 13.0 GO:0003702 obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.1 0.4 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.5 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 2.5 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1 0.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 3.1 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 2.4 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.1 0.2 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 0.5 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.1 0.8 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 0.3 GO:0004359 glutaminase activity(GO:0004359)
0.1 2.1 GO:0070888 E-box binding(GO:0070888)
0.1 0.2 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 0.2 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.1 2.1 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.1 1.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 3.4 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 0.3 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.7 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 4.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 0.5 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 0.7 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 5.2 GO:0003777 microtubule motor activity(GO:0003777)
0.1 0.5 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.7 GO:0001671 ATPase activator activity(GO:0001671)
0.1 1.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.3 GO:0070061 fructose binding(GO:0070061)
0.1 0.3 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 0.5 GO:0017127 cholesterol transporter activity(GO:0017127)
0.1 1.0 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.7 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.1 0.9 GO:0015605 organophosphate ester transmembrane transporter activity(GO:0015605)
0.1 0.3 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.1 2.5 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.1 0.9 GO:0010181 FMN binding(GO:0010181)
0.1 1.1 GO:0005522 profilin binding(GO:0005522)
0.1 0.6 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.4 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.4 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 2.0 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 1.0 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.1 0.7 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.1 0.4 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 0.4 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.1 0.5 GO:0001968 fibronectin binding(GO:0001968)
0.1 3.4 GO:0004221 obsolete ubiquitin thiolesterase activity(GO:0004221)
0.1 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 1.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 1.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 0.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 1.6 GO:0030145 manganese ion binding(GO:0030145)
0.0 1.1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 2.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.2 GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)
0.0 0.7 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.2 GO:0017163 obsolete basal transcription repressor activity(GO:0017163)
0.0 0.1 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.0 1.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.5 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.0 0.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 1.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 2.1 GO:0003704 obsolete specific RNA polymerase II transcription factor activity(GO:0003704)
0.0 0.4 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 1.9 GO:0050661 NADP binding(GO:0050661)
0.0 0.3 GO:0004835 tubulin-tyrosine ligase activity(GO:0004835)
0.0 0.9 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.3 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.3 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.7 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.7 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.8 GO:0000146 microfilament motor activity(GO:0000146)
0.0 1.7 GO:0008026 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 0.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) core promoter sequence-specific DNA binding(GO:0001046) core promoter binding(GO:0001047)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 3.0 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.2 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922)
0.0 0.6 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.8 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.5 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.4 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 2.2 GO:0008017 microtubule binding(GO:0008017)
0.0 5.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.7 GO:0003682 chromatin binding(GO:0003682)
0.0 0.2 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.3 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.0 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.5 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 39.0 GO:0003677 DNA binding(GO:0003677)
0.0 10.0 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.8 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 5.3 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.7 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.8 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity(GO:0008757)
0.0 0.1 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.4 GO:0005048 signal sequence binding(GO:0005048)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.5 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.3 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.5 GO:0015405 primary active transmembrane transporter activity(GO:0015399) P-P-bond-hydrolysis-driven transmembrane transporter activity(GO:0015405) ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.5 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.1 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.3 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.2 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.2 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.1 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0042805 actinin binding(GO:0042805)
0.0 0.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.2 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.0 GO:0044620 ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) phosphopantetheine binding(GO:0031177) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0 0.2 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 0.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.5 GO:0050136 NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 6.8 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 5.3 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.1 6.2 SIG_BCR_SIGNALING_PATHWAY Members of the BCR signaling pathway
0.1 1.6 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.8 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.2 ST_GAQ_PATHWAY G alpha q Pathway
0.0 0.7 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.0 1.1 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 2.0 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.0 0.4 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.5 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.0 0.2 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.