Motif ID: E4F1
Z-value: 0.982
Transcription factors associated with E4F1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| E4F1 | ENSG00000167967.11 | E4F1 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.6 | GO:0035283 | rhombomere 3 development(GO:0021569) rhombomere 5 development(GO:0021571) cranial nerve structural organization(GO:0021604) facial nerve morphogenesis(GO:0021610) facial nerve structural organization(GO:0021612) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284) |
| 0.1 | 0.6 | GO:0033602 | negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of dopamine secretion(GO:0033602) |
| 0.1 | 1.2 | GO:0001706 | endoderm formation(GO:0001706) |
| 0.1 | 1.8 | GO:0050812 | acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812) |
| 0.1 | 0.2 | GO:0014028 | notochord formation(GO:0014028) axial mesoderm morphogenesis(GO:0048319) |
| 0.1 | 1.7 | GO:0050732 | negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) |
| 0.1 | 0.5 | GO:0071480 | cellular response to gamma radiation(GO:0071480) |
| 0.1 | 0.1 | GO:0014834 | skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834) |
| 0.1 | 2.6 | GO:0045740 | positive regulation of DNA replication(GO:0045740) |
| 0.0 | 0.9 | GO:0006984 | ER-nucleus signaling pathway(GO:0006984) |
| 0.0 | 0.2 | GO:0019046 | release from viral latency(GO:0019046) |
| 0.0 | 0.1 | GO:0034625 | fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.0 | 3.0 | GO:0006521 | regulation of cellular amino acid metabolic process(GO:0006521) |
| 0.0 | 0.3 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) dendritic cell differentiation(GO:0097028) |
| 0.0 | 1.4 | GO:0015914 | phospholipid transport(GO:0015914) |
| 0.0 | 0.2 | GO:0019985 | translesion synthesis(GO:0019985) |
| 0.0 | 0.2 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905) |
| 0.0 | 0.2 | GO:0070189 | kynurenine metabolic process(GO:0070189) |
| 0.0 | 0.9 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.0 | 0.1 | GO:0045767 | obsolete regulation of anti-apoptosis(GO:0045767) |
| 0.0 | 0.1 | GO:0000729 | DNA double-strand break processing(GO:0000729) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.0 | GO:0005839 | proteasome core complex(GO:0005839) |
| 0.0 | 0.6 | GO:0030673 | axolemma(GO:0030673) |
| 0.0 | 0.2 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.0 | 0.1 | GO:0031372 | UBC13-MMS2 complex(GO:0031372) |
| 0.0 | 0.7 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 1.8 | GO:0008287 | protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293) |
| 0.0 | 0.2 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.0 | 0.2 | GO:0070688 | MLL5-L complex(GO:0070688) |
| 0.0 | 0.4 | GO:0019861 | obsolete flagellum(GO:0019861) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.8 | GO:0004741 | magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
| 0.2 | 1.2 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
| 0.2 | 0.6 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
| 0.1 | 0.5 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
| 0.1 | 0.6 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.1 | 3.0 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.1 | 1.7 | GO:0043560 | insulin receptor substrate binding(GO:0043560) |
| 0.1 | 1.4 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.1 | 0.7 | GO:0016944 | obsolete RNA polymerase II transcription elongation factor activity(GO:0016944) |
| 0.1 | 0.2 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 0.0 | 0.2 | GO:0070548 | 1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847) L-glutamine aminotransferase activity(GO:0070548) |
| 0.0 | 0.8 | GO:0008186 | RNA-dependent ATPase activity(GO:0008186) |
| 0.0 | 0.1 | GO:0009922 | fatty acid elongase activity(GO:0009922) |
| 0.0 | 0.9 | GO:0005518 | collagen binding(GO:0005518) |
| 0.0 | 0.2 | GO:0008242 | omega peptidase activity(GO:0008242) |
| 0.0 | 2.6 | GO:0008083 | growth factor activity(GO:0008083) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.2 | ST_JNK_MAPK_PATHWAY | JNK MAPK Pathway |
| 0.0 | 0.9 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
