Motif ID: EMX1

Z-value: 1.248


Transcription factors associated with EMX1:

Gene SymbolEntrez IDGene Name
EMX1 ENSG00000135638.9 EMX1



Activity profile for motif EMX1.

activity profile for motif EMX1


Sorted Z-values histogram for motif EMX1

Sorted Z-values for motif EMX1



Network of associatons between targets according to the STRING database.



First level regulatory network of EMX1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_169418195 3.959 ENST00000261509.6
ENST00000335742.7
PALLD

palladin, cytoskeletal associated protein

chr11_-_111794446 3.573 ENST00000527950.1
CRYAB
crystallin, alpha B
chr8_-_49833978 3.004 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr4_-_143226979 2.969 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chrX_-_13835147 2.822 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr1_-_151965048 2.761 ENST00000368809.1
S100A10
S100 calcium binding protein A10
chr5_+_135394840 2.695 ENST00000503087.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr12_-_91546926 2.458 ENST00000550758.1
DCN
decorin
chr12_+_81110684 2.310 ENST00000228644.3
MYF5
myogenic factor 5
chr4_-_143227088 2.241 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr8_-_49834299 2.204 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr5_+_125758865 2.200 ENST00000542322.1
ENST00000544396.1
GRAMD3

GRAM domain containing 3

chr13_-_38172863 2.180 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
POSTN





periostin, osteoblast specific factor





chr5_+_125758813 2.150 ENST00000285689.3
ENST00000515200.1
GRAMD3

GRAM domain containing 3

chr4_+_169418255 1.965 ENST00000505667.1
ENST00000511948.1
PALLD

palladin, cytoskeletal associated protein

chr13_+_73632897 1.905 ENST00000377687.4
KLF5
Kruppel-like factor 5 (intestinal)
chr3_-_151034734 1.883 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr19_-_51522955 1.808 ENST00000358789.3
KLK10
kallikrein-related peptidase 10
chr1_-_68698222 1.636 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS



wntless Wnt ligand secretion mediator



chr7_+_130126165 1.634 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
MEST


mesoderm specific transcript


chr13_-_110438914 1.594 ENST00000375856.3
IRS2
insulin receptor substrate 2
chr5_+_36608422 1.582 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr7_+_130126012 1.545 ENST00000341441.5
MEST
mesoderm specific transcript
chr12_+_26348246 1.512 ENST00000422622.2
SSPN
sarcospan
chr3_+_158991025 1.488 ENST00000337808.6
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr12_-_50616382 1.479 ENST00000552783.1
LIMA1
LIM domain and actin binding 1
chr12_-_53012343 1.459 ENST00000305748.3
KRT73
keratin 73
chr1_-_95391315 1.449 ENST00000545882.1
ENST00000415017.1
CNN3

calponin 3, acidic

chr10_-_93392811 1.380 ENST00000238994.5
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr7_-_107642348 1.359 ENST00000393561.1
LAMB1
laminin, beta 1
chr3_-_123339343 1.312 ENST00000578202.1
MYLK
myosin light chain kinase
chr18_-_21891460 1.250 ENST00000357041.4
OSBPL1A
oxysterol binding protein-like 1A
chr8_+_32579341 1.232 ENST00000519240.1
ENST00000539990.1
NRG1

neuregulin 1

chr2_-_190927447 1.230 ENST00000260950.4
MSTN
myostatin
chr17_-_39743139 1.219 ENST00000167586.6
KRT14
keratin 14
chr5_-_82969405 1.201 ENST00000510978.1
HAPLN1
hyaluronan and proteoglycan link protein 1
chr3_+_158787041 1.166 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1


IQCJ-SCHIP1 readthrough


chr12_-_28123206 1.126 ENST00000542963.1
ENST00000535992.1
PTHLH

parathyroid hormone-like hormone

chr6_+_151646800 1.089 ENST00000354675.6
AKAP12
A kinase (PRKA) anchor protein 12
chr10_-_5046042 1.082 ENST00000421196.3
ENST00000455190.1
AKR1C2

aldo-keto reductase family 1, member C2

chr5_+_53751445 1.074 ENST00000302005.1
HSPB3
heat shock 27kDa protein 3
chr18_+_3447572 1.050 ENST00000548489.2
TGIF1
TGFB-induced factor homeobox 1
chr17_-_7307358 1.028 ENST00000535512.1
ENST00000576017.1
ENST00000302422.3
TMEM256-PLSCR3
TMEM256

TMEM256-PLSCR3 readthrough (NMD candidate)
transmembrane protein 256

chr2_-_179672142 1.019 ENST00000342992.6
ENST00000360870.5
ENST00000460472.2
ENST00000589042.1
ENST00000591111.1
ENST00000342175.6
ENST00000359218.5
TTN






titin






chrX_-_106243451 0.991 ENST00000355610.4
ENST00000535534.1
MORC4

MORC family CW-type zinc finger 4

chr18_-_33702078 0.969 ENST00000586829.1
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr18_-_33709268 0.931 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
SLC39A6


solute carrier family 39 (zinc transporter), member 6


chr12_-_28122980 0.919 ENST00000395868.3
ENST00000534890.1
PTHLH

parathyroid hormone-like hormone

chr12_+_26348429 0.873 ENST00000242729.2
SSPN
sarcospan
chr3_+_35722487 0.859 ENST00000441454.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr14_-_70883708 0.852 ENST00000256366.4
SYNJ2BP
synaptojanin 2 binding protein
chr3_-_99595037 0.850 ENST00000383694.2
FILIP1L
filamin A interacting protein 1-like
chr8_+_70404996 0.846 ENST00000402687.4
ENST00000419716.3
SULF1

sulfatase 1

chr3_-_99594948 0.839 ENST00000471562.1
ENST00000495625.2
FILIP1L

filamin A interacting protein 1-like

chr2_-_208031943 0.833 ENST00000421199.1
ENST00000457962.1
KLF7

Kruppel-like factor 7 (ubiquitous)

chr20_+_60174827 0.799 ENST00000543233.1
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr16_+_57279004 0.796 ENST00000219204.3
ARL2BP
ADP-ribosylation factor-like 2 binding protein
chr17_-_10325261 0.762 ENST00000403437.2
MYH8
myosin, heavy chain 8, skeletal muscle, perinatal
chr4_-_186696425 0.760 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2


sorbin and SH3 domain containing 2


chr5_+_174151536 0.752 ENST00000239243.6
ENST00000507785.1
MSX2

msh homeobox 2

chr1_+_202317815 0.702 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
PPP1R12B


protein phosphatase 1, regulatory subunit 12B


chr1_+_84609944 0.702 ENST00000370685.3
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr2_+_234627424 0.668 ENST00000373409.3
UGT1A4
UDP glucuronosyltransferase 1 family, polypeptide A4
chr12_+_54378923 0.664 ENST00000303460.4
HOXC10
homeobox C10
chr10_+_17270214 0.647 ENST00000544301.1
VIM
vimentin
chr5_-_95297534 0.646 ENST00000513343.1
ENST00000431061.2
ELL2

elongation factor, RNA polymerase II, 2

chr1_-_242162375 0.642 ENST00000357246.3
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr11_-_129062093 0.632 ENST00000310343.9
ARHGAP32
Rho GTPase activating protein 32
chr16_-_53737722 0.622 ENST00000569716.1
ENST00000562588.1
ENST00000562230.1
ENST00000379925.3
ENST00000563746.1
ENST00000568653.3
RPGRIP1L





RPGRIP1-like





chr12_-_85306594 0.616 ENST00000266682.5
SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr16_-_66764119 0.615 ENST00000569320.1
DYNC1LI2
dynein, cytoplasmic 1, light intermediate chain 2
chr6_-_109777128 0.613 ENST00000358807.3
ENST00000358577.3
MICAL1

microtubule associated monooxygenase, calponin and LIM domain containing 1

chr2_-_207082748 0.605 ENST00000407325.2
ENST00000411719.1
GPR1

G protein-coupled receptor 1

chr17_-_63822563 0.584 ENST00000317442.8
CEP112
centrosomal protein 112kDa
chr3_+_111717600 0.565 ENST00000273368.4
TAGLN3
transgelin 3
chr9_-_107690420 0.555 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
ABCA1


ATP-binding cassette, sub-family A (ABC1), member 1


chr4_+_41614909 0.555 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1


LIM and calponin homology domains 1


chr6_-_91296602 0.537 ENST00000369325.3
ENST00000369327.3
MAP3K7

mitogen-activated protein kinase kinase kinase 7

chr10_-_127505167 0.537 ENST00000368786.1
UROS
uroporphyrinogen III synthase
chr1_+_225600404 0.531 ENST00000366845.2
AC092811.1
AC092811.1
chr16_-_53737795 0.530 ENST00000262135.4
ENST00000564374.1
ENST00000566096.1
RPGRIP1L


RPGRIP1-like


chr21_-_43346790 0.529 ENST00000329623.7
C2CD2
C2 calcium-dependent domain containing 2
chr6_-_91296737 0.520 ENST00000369332.3
ENST00000369329.3
MAP3K7

mitogen-activated protein kinase kinase kinase 7

chr12_+_15699286 0.517 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
PTPRO



protein tyrosine phosphatase, receptor type, O



chr3_-_46000064 0.503 ENST00000433878.1
FYCO1
FYVE and coiled-coil domain containing 1
chr3_+_35721106 0.500 ENST00000474696.1
ENST00000412048.1
ENST00000396482.2
ENST00000432682.1
ARPP21



cAMP-regulated phosphoprotein, 21kDa



chr3_+_111717511 0.495 ENST00000478951.1
ENST00000393917.2
TAGLN3

transgelin 3

chr1_+_152881014 0.490 ENST00000368764.3
ENST00000392667.2
IVL

involucrin

chr8_+_98900132 0.489 ENST00000520016.1
MATN2
matrilin 2
chr5_-_16916624 0.488 ENST00000513882.1
MYO10
myosin X
chr1_+_210501589 0.487 ENST00000413764.2
ENST00000541565.1
HHAT

hedgehog acyltransferase

chr3_+_130745688 0.487 ENST00000510769.1
ENST00000429253.2
ENST00000356918.4
ENST00000510688.1
ENST00000511262.1
ENST00000383366.4
NEK11





NIMA-related kinase 11





chr4_+_70796784 0.460 ENST00000246891.4
ENST00000444405.3
CSN1S1

casein alpha s1

chr14_+_74034310 0.456 ENST00000538782.1
ACOT2
acyl-CoA thioesterase 2
chr2_-_217560248 0.452 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr18_-_61329118 0.447 ENST00000332821.8
ENST00000283752.5
SERPINB3

serpin peptidase inhibitor, clade B (ovalbumin), member 3

chr6_-_46293378 0.446 ENST00000330430.6
RCAN2
regulator of calcineurin 2
chr5_-_95297678 0.441 ENST00000237853.4
ELL2
elongation factor, RNA polymerase II, 2
chr3_+_111718036 0.436 ENST00000455401.2
TAGLN3
transgelin 3
chr1_-_68698197 0.423 ENST00000370973.2
ENST00000370971.1
WLS

wntless Wnt ligand secretion mediator

chr19_+_13049413 0.418 ENST00000316448.5
ENST00000588454.1
CALR

calreticulin

chr1_-_173174681 0.415 ENST00000367718.1
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr11_-_104827425 0.404 ENST00000393150.3
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr2_+_109237717 0.401 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr6_+_39760129 0.398 ENST00000274867.4
DAAM2
dishevelled associated activator of morphogenesis 2
chr1_-_21377383 0.395 ENST00000374935.3
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr8_+_105352050 0.392 ENST00000297581.2
DCSTAMP
dendrocyte expressed seven transmembrane protein
chr6_-_100912785 0.386 ENST00000369208.3
SIM1
single-minded family bHLH transcription factor 1
chr19_-_7968427 0.379 ENST00000539278.1
AC010336.1
Uncharacterized protein
chr13_-_36050819 0.377 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr9_+_26956371 0.369 ENST00000380062.5
ENST00000518614.1
IFT74

intraflagellar transport 74 homolog (Chlamydomonas)

chr4_-_10686475 0.365 ENST00000226951.6
CLNK
cytokine-dependent hematopoietic cell linker
chr7_-_143599207 0.363 ENST00000355951.2
ENST00000479870.1
ENST00000478172.1
FAM115A


family with sequence similarity 115, member A


chr10_+_5005598 0.355 ENST00000442997.1
AKR1C1
aldo-keto reductase family 1, member C1
chr15_+_62853562 0.353 ENST00000561311.1
TLN2
talin 2
chr7_-_27169801 0.338 ENST00000511914.1
HOXA4
homeobox A4
chr17_-_7145475 0.338 ENST00000571129.1
ENST00000571253.1
ENST00000573928.1
GABARAP


GABA(A) receptor-associated protein


chr2_-_86850949 0.329 ENST00000237455.4
RNF103
ring finger protein 103
chr12_-_10959892 0.323 ENST00000240615.2
TAS2R8
taste receptor, type 2, member 8
chr5_-_9630463 0.317 ENST00000382492.2
TAS2R1
taste receptor, type 2, member 1
chr2_-_145277569 0.314 ENST00000303660.4
ZEB2
zinc finger E-box binding homeobox 2
chr6_-_111927449 0.313 ENST00000368761.5
ENST00000392556.4
ENST00000340026.6
TRAF3IP2


TRAF3 interacting protein 2


chr18_+_46065393 0.312 ENST00000256413.3
CTIF
CBP80/20-dependent translation initiation factor
chr7_+_12727250 0.300 ENST00000404894.1
ARL4A
ADP-ribosylation factor-like 4A
chr1_-_48937821 0.299 ENST00000396199.3
SPATA6
spermatogenesis associated 6
chr1_-_94586651 0.285 ENST00000535735.1
ENST00000370225.3
ABCA4

ATP-binding cassette, sub-family A (ABC1), member 4

chr11_+_77532233 0.284 ENST00000525409.1
AAMDC
adipogenesis associated, Mth938 domain containing
chr5_+_66300446 0.283 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr6_+_52535878 0.276 ENST00000211314.4
TMEM14A
transmembrane protein 14A
chr20_+_18488137 0.272 ENST00000450074.1
ENST00000262544.2
ENST00000336714.3
ENST00000377475.3
SEC23B



Sec23 homolog B (S. cerevisiae)



chr17_+_79650962 0.272 ENST00000329138.4
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr1_-_48937838 0.267 ENST00000371847.3
SPATA6
spermatogenesis associated 6
chr5_-_176889381 0.264 ENST00000393563.4
ENST00000512501.1
DBN1

drebrin 1

chr16_-_11036300 0.264 ENST00000331808.4
DEXI
Dexi homolog (mouse)
chr5_-_148929848 0.261 ENST00000504676.1
ENST00000515435.1
CSNK1A1

casein kinase 1, alpha 1

chr2_-_1629176 0.261 ENST00000366424.2
AC144450.2
AC144450.2
chr11_-_104905840 0.253 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1










caspase 1, apoptosis-related cysteine peptidase










chr18_+_56530136 0.251 ENST00000591083.1
ZNF532
zinc finger protein 532
chr5_+_115177178 0.248 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr7_-_100860851 0.246 ENST00000223127.3
PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr14_-_78083112 0.245 ENST00000216484.2
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chrX_-_14047996 0.244 ENST00000380523.4
ENST00000398355.3
GEMIN8

gem (nuclear organelle) associated protein 8

chr10_-_71169031 0.242 ENST00000373307.1
TACR2
tachykinin receptor 2
chr13_-_44735393 0.240 ENST00000400419.1
SMIM2
small integral membrane protein 2
chr19_+_49990811 0.240 ENST00000391857.4
ENST00000467825.2
RPL13A

ribosomal protein L13a

chrX_+_78003204 0.239 ENST00000435339.3
ENST00000514744.1
LPAR4

lysophosphatidic acid receptor 4

chr19_-_58951496 0.238 ENST00000254166.3
ZNF132
zinc finger protein 132
chr8_+_22424551 0.235 ENST00000523348.1
SORBS3
sorbin and SH3 domain containing 3
chr3_-_151047327 0.233 ENST00000325602.5
P2RY13
purinergic receptor P2Y, G-protein coupled, 13
chr11_-_128894053 0.225 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr11_-_118134997 0.220 ENST00000278937.2
MPZL2
myelin protein zero-like 2
chr10_-_28571015 0.218 ENST00000375719.3
ENST00000375732.1
MPP7

membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)

chr12_-_10978957 0.217 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chrX_+_46696372 0.215 ENST00000218340.3
RP2
retinitis pigmentosa 2 (X-linked recessive)
chr18_+_616672 0.213 ENST00000338387.7
CLUL1
clusterin-like 1 (retinal)
chr12_+_18414446 0.210 ENST00000433979.1
PIK3C2G
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
chrX_+_54947229 0.209 ENST00000442098.1
ENST00000430420.1
ENST00000453081.1
ENST00000173898.7
ENST00000319167.8
ENST00000375022.4
ENST00000399736.1
ENST00000440072.1
ENST00000420798.2
ENST00000431115.1
ENST00000440759.1
ENST00000375041.2
TRO











trophinin











chr4_-_74486217 0.201 ENST00000335049.5
ENST00000307439.5
RASSF6

Ras association (RalGDS/AF-6) domain family member 6

chr7_-_82792215 0.197 ENST00000333891.9
ENST00000423517.2
PCLO

piccolo presynaptic cytomatrix protein

chr6_-_111927062 0.192 ENST00000359831.4
TRAF3IP2
TRAF3 interacting protein 2
chr17_+_46970134 0.190 ENST00000503641.1
ENST00000514808.1
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr15_-_72563585 0.188 ENST00000287196.9
ENST00000260376.7
PARP6

poly (ADP-ribose) polymerase family, member 6

chr11_+_77532155 0.186 ENST00000532481.1
ENST00000526415.1
ENST00000393427.2
ENST00000527134.1
ENST00000304716.8
AAMDC




adipogenesis associated, Mth938 domain containing




chr1_+_226013047 0.183 ENST00000366837.4
EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)
chr7_-_105029812 0.183 ENST00000482897.1
SRPK2
SRSF protein kinase 2
chr4_+_88754113 0.181 ENST00000560249.1
ENST00000540395.1
ENST00000511670.1
ENST00000361056.3
MEPE



matrix extracellular phosphoglycoprotein



chr7_-_99716952 0.177 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
TAF6










TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa










chr12_-_48164812 0.176 ENST00000549151.1
ENST00000548919.1
RAPGEF3

Rap guanine nucleotide exchange factor (GEF) 3

chr1_+_86934526 0.174 ENST00000394711.1
CLCA1
chloride channel accessory 1
chr12_-_65146636 0.173 ENST00000418919.2
GNS
glucosamine (N-acetyl)-6-sulfatase
chr17_+_46970178 0.172 ENST00000393366.2
ENST00000506855.1
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr1_-_67266939 0.172 ENST00000304526.2
INSL5
insulin-like 5
chr11_-_117748138 0.171 ENST00000527717.1
FXYD6
FXYD domain containing ion transport regulator 6
chr1_+_151735431 0.170 ENST00000321531.5
ENST00000315067.8
OAZ3

ornithine decarboxylase antizyme 3

chr2_+_211421262 0.169 ENST00000233072.5
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr3_-_69129501 0.169 ENST00000540295.1
ENST00000415609.2
ENST00000361055.4
ENST00000349511.4
UBA3



ubiquitin-like modifier activating enzyme 3



chrX_+_38211777 0.163 ENST00000039007.4
OTC
ornithine carbamoyltransferase
chr17_+_46970127 0.159 ENST00000355938.5
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr12_-_10962767 0.159 ENST00000240691.2
TAS2R9
taste receptor, type 2, member 9
chr13_-_47471155 0.158 ENST00000543956.1
ENST00000542664.1
HTR2A

5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled

chr18_-_13915530 0.157 ENST00000327606.3
MC2R
melanocortin 2 receptor (adrenocorticotropic hormone)
chr1_+_117544366 0.157 ENST00000256652.4
ENST00000369470.1
CD101

CD101 molecule

chr7_-_83824169 0.153 ENST00000265362.4
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr7_-_107443652 0.150 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
SLC26A3


solute carrier family 26 (anion exchanger), member 3


chr7_-_81399329 0.150 ENST00000453411.1
ENST00000444829.2
HGF

hepatocyte growth factor (hepapoietin A; scatter factor)

chr14_-_37051798 0.149 ENST00000258829.5
NKX2-8
NK2 homeobox 8
chr5_+_148737562 0.148 ENST00000274569.4
PCYOX1L
prenylcysteine oxidase 1 like
chr8_+_105235572 0.146 ENST00000523362.1
RIMS2
regulating synaptic membrane exocytosis 2
chr5_+_140602904 0.145 ENST00000515856.2
ENST00000239449.4
PCDHB14

protocadherin beta 14

chr12_+_20963647 0.145 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr19_+_50016610 0.144 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr11_-_117747607 0.144 ENST00000540359.1
ENST00000539526.1
FXYD6

FXYD domain containing ion transport regulator 6

chr6_-_138539627 0.143 ENST00000527246.2
PBOV1
prostate and breast cancer overexpressed 1
chr1_-_149900122 0.143 ENST00000271628.8
SF3B4
splicing factor 3b, subunit 4, 49kDa
chr1_-_48866517 0.143 ENST00000371841.1
SPATA6
spermatogenesis associated 6
chr1_-_151762943 0.139 ENST00000368825.3
ENST00000368823.1
ENST00000458431.2
ENST00000368827.6
ENST00000368824.3
TDRKH




tudor and KH domain containing




chr1_-_10532531 0.137 ENST00000377036.2
ENST00000377038.3
DFFA

DNA fragmentation factor, 45kDa, alpha polypeptide

chr4_-_74486347 0.135 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr7_+_43152191 0.133 ENST00000395891.2
HECW1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr2_-_74619152 0.133 ENST00000440727.1
ENST00000409240.1
DCTN1

dynactin 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 5.2 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.5 2.0 GO:0060649 nipple development(GO:0060618) mammary gland bud elongation(GO:0060649) nipple morphogenesis(GO:0060658) nipple sheath formation(GO:0060659)
0.4 1.2 GO:0014889 muscle atrophy(GO:0014889) regulation of skeletal muscle tissue growth(GO:0048631)
0.4 1.6 GO:0031223 auditory behavior(GO:0031223) malate-aspartate shuttle(GO:0043490)
0.3 1.0 GO:0031034 skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.3 1.2 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.3 2.3 GO:0042693 muscle cell fate commitment(GO:0042693)
0.3 1.6 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.2 2.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 1.9 GO:0032528 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.2 1.4 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.2 1.2 GO:0022038 corpus callosum development(GO:0022038)
0.2 1.3 GO:0060414 aorta development(GO:0035904) aorta morphogenesis(GO:0035909) aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 1.1 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.2 0.8 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 0.4 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.1 0.5 GO:0071418 uroporphyrinogen III biosynthetic process(GO:0006780) cellular response to amine stimulus(GO:0071418)
0.1 1.4 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.1 1.2 GO:0010658 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1 0.6 GO:0034204 Cdc42 protein signal transduction(GO:0032488) lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 0.7 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 1.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.8 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1 0.6 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820) proline transport(GO:0015824)
0.1 0.5 GO:0010224 response to UV-B(GO:0010224)
0.1 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.1 0.2 GO:0046520 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.1 0.5 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.5 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.1 1.8 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.1 GO:0050942 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.1 0.5 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 1.5 GO:0031529 ruffle organization(GO:0031529)
0.1 1.4 GO:0034605 cellular response to heat(GO:0034605)
0.1 4.5 GO:0009408 response to heat(GO:0009408)
0.1 0.2 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.1 0.2 GO:1902414 protein localization to adherens junction(GO:0071896) protein localization to cell junction(GO:1902414)
0.1 0.2 GO:0070781 response to biotin(GO:0070781)
0.1 0.3 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.8 GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein(GO:0042517)
0.0 0.4 GO:0048387 protein maturation by protein folding(GO:0022417) negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 2.1 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.2 GO:0071400 cellular response to oleic acid(GO:0071400)
0.0 4.8 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 1.1 GO:0006693 prostaglandin metabolic process(GO:0006693)
0.0 0.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.1 GO:0046621 negative regulation of organ growth(GO:0046621)
0.0 0.7 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.1 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.0 0.1 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.3 GO:0007603 phototransduction, visible light(GO:0007603)
0.0 0.9 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.6 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.2 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.3 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 2.8 GO:0007498 mesoderm development(GO:0007498)
0.0 0.2 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 0.1 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.7 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.1 GO:0034310 primary alcohol catabolic process(GO:0034310)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.4 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.4 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 2.1 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.4 GO:0007128 meiotic prophase I(GO:0007128)
0.0 0.1 GO:0000098 sulfur amino acid catabolic process(GO:0000098) sulfur compound catabolic process(GO:0044273)
0.0 0.5 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.5 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.1 GO:0032472 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) Golgi calcium ion transport(GO:0032472) manganese ion homeostasis(GO:0055071)
0.0 0.1 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.7 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.1 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.1 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.2 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.0 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.2 GO:0008272 sulfate transport(GO:0008272)
0.0 0.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 1.2 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.0 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.3 GO:0001756 somitogenesis(GO:0001756) somite development(GO:0061053)
0.0 0.1 GO:0034382 triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372) chylomicron remnant clearance(GO:0034382) phosphatidylcholine catabolic process(GO:0034638) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0 0.1 GO:0050680 negative regulation of epithelial cell proliferation(GO:0050680)
0.0 0.3 GO:0036503 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) ERAD pathway(GO:0036503)
0.0 0.0 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0 6.6 GO:0007010 cytoskeleton organization(GO:0007010)
0.0 1.2 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 0.6 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) actin-mediated cell contraction(GO:0070252)
0.0 0.3 GO:0050873 brown fat cell differentiation(GO:0050873)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0005607 laminin-2 complex(GO:0005607)
0.2 2.5 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 1.4 GO:0042587 glycogen granule(GO:0042587)
0.1 1.9 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 1.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.7 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 4.9 GO:0005884 actin filament(GO:0005884)
0.1 1.6 GO:0043205 fibril(GO:0043205)
0.1 0.3 GO:0032585 multivesicular body membrane(GO:0032585)
0.1 1.0 GO:0000421 autophagosome membrane(GO:0000421)
0.1 2.3 GO:0045095 keratin filament(GO:0045095)
0.1 1.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.5 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.4 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 1.1 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.4 GO:0031430 M band(GO:0031430)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 2.6 GO:0016459 myosin complex(GO:0016459)
0.0 1.7 GO:0042641 actomyosin(GO:0042641)
0.0 0.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 1.1 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.6 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.2 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.5 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.3 GO:0030286 dynein complex(GO:0030286)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.5 GO:0001533 cornified envelope(GO:0001533)
0.0 1.0 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.9 GO:0005882 intermediate filament(GO:0005882)
0.0 0.5 GO:0030018 Z disc(GO:0030018)
0.0 0.2 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.8 GO:0043197 dendritic spine(GO:0043197)
0.0 0.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 3.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.2 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
1.0 5.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.3 1.1 GO:0047026 androsterone dehydrogenase (A-specific) activity(GO:0047026)
0.3 1.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 1.0 GO:0051393 alpha-actinin binding(GO:0051393)
0.2 0.4 GO:0047718 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115) indanol dehydrogenase activity(GO:0047718)
0.2 1.8 GO:0016595 glutamate binding(GO:0016595)
0.1 1.4 GO:0030172 troponin C binding(GO:0030172)
0.1 0.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.6 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 1.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 3.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.5 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 5.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 1.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 1.2 GO:0008527 taste receptor activity(GO:0008527)
0.1 1.1 GO:0016944 obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.1 2.1 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 1.5 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 1.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 2.0 GO:0070888 E-box binding(GO:0070888)
0.1 0.5 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.1 0.8 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 0.2 GO:0043199 sulfate binding(GO:0043199)
0.1 0.7 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.1 0.5 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 1.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0 1.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.9 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.4 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.2 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.6 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.4 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 2.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.2 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.7 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.2 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.1 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.0 0.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 1.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.2 GO:0051378 serotonin binding(GO:0051378)
0.0 0.1 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.0 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 1.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 2.7 GO:0003702 obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0 0.2 GO:0042301 phosphate ion binding(GO:0042301)
0.0 1.7 GO:0008201 heparin binding(GO:0008201)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.0 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 1.2 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.6 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.2 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.