Motif ID: EMX2
Z-value: 0.999
Transcription factors associated with EMX2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| EMX2 | ENSG00000170370.10 | EMX2 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.0 | GO:0071380 | cellular response to prostaglandin E stimulus(GO:0071380) |
| 0.3 | 0.8 | GO:0010430 | ethanol catabolic process(GO:0006068) fatty acid omega-oxidation(GO:0010430) |
| 0.2 | 2.4 | GO:0006491 | N-glycan processing(GO:0006491) |
| 0.1 | 0.9 | GO:0009082 | branched-chain amino acid biosynthetic process(GO:0009082) |
| 0.1 | 0.4 | GO:1901419 | regulation of response to alcohol(GO:1901419) |
| 0.1 | 0.3 | GO:0010273 | regulation of oxidative phosphorylation(GO:0002082) detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169) |
| 0.1 | 0.6 | GO:1901503 | ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503) |
| 0.1 | 0.3 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.1 | 0.6 | GO:0015862 | uridine transport(GO:0015862) |
| 0.1 | 0.3 | GO:0006726 | eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474) |
| 0.1 | 0.2 | GO:0051661 | Golgi localization(GO:0051645) maintenance of centrosome location(GO:0051661) |
| 0.1 | 0.5 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.1 | 0.2 | GO:0000114 | obsolete regulation of transcription involved in G1 phase of mitotic cell cycle(GO:0000114) |
| 0.0 | 0.1 | GO:0019521 | aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521) |
| 0.0 | 0.2 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
| 0.0 | 0.1 | GO:0014889 | muscle atrophy(GO:0014889) |
| 0.0 | 0.1 | GO:0042097 | interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404) |
| 0.0 | 0.4 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) dendritic cell differentiation(GO:0097028) |
| 0.0 | 0.7 | GO:0002504 | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504) |
| 0.0 | 0.5 | GO:0071044 | histone mRNA catabolic process(GO:0071044) |
| 0.0 | 0.3 | GO:0046051 | GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051) |
| 0.0 | 0.5 | GO:0060736 | prostate gland growth(GO:0060736) |
| 0.0 | 0.1 | GO:0008065 | establishment of blood-nerve barrier(GO:0008065) |
| 0.0 | 0.1 | GO:0032057 | negative regulation of translational initiation in response to stress(GO:0032057) |
| 0.0 | 0.1 | GO:0019441 | tryptophan catabolic process to kynurenine(GO:0019441) |
| 0.0 | 0.1 | GO:0060025 | regulation of synaptic activity(GO:0060025) |
| 0.0 | 0.1 | GO:1904037 | positive regulation of epithelial cell apoptotic process(GO:1904037) positive regulation of endothelial cell apoptotic process(GO:2000353) |
| 0.0 | 0.3 | GO:0032814 | regulation of natural killer cell activation(GO:0032814) |
| 0.0 | 0.6 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.0 | 0.1 | GO:0008628 | hormone-mediated apoptotic signaling pathway(GO:0008628) |
| 0.0 | 0.4 | GO:0051925 | obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925) |
| 0.0 | 0.1 | GO:0045652 | regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532) |
| 0.0 | 0.0 | GO:0035461 | vitamin transmembrane transport(GO:0035461) |
| 0.0 | 0.1 | GO:0006072 | glycerol-3-phosphate metabolic process(GO:0006072) |
| 0.0 | 0.1 | GO:0055091 | phospholipid homeostasis(GO:0055091) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.4 | GO:0005726 | perichromatin fibrils(GO:0005726) |
| 0.1 | 0.4 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.0 | 0.5 | GO:0016442 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
| 0.0 | 0.3 | GO:0033162 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
| 0.0 | 0.7 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.0 | 0.2 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.0 | 1.5 | GO:0000786 | nucleosome(GO:0000786) |
| 0.0 | 0.6 | GO:0097525 | spliceosomal snRNP complex(GO:0097525) |
| 0.0 | 0.2 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.0 | 0.1 | GO:0005851 | eukaryotic translation initiation factor 2B complex(GO:0005851) |
| 0.0 | 0.1 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 0.0 | 0.4 | GO:0042611 | MHC protein complex(GO:0042611) |
| 0.0 | 0.6 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 0.4 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 0.3 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.0 | 0.1 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.0 | 0.1 | GO:0042575 | DNA polymerase complex(GO:0042575) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 2.2 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 0.3 | 0.8 | GO:0035276 | ethanol binding(GO:0035276) |
| 0.2 | 0.6 | GO:0050062 | long-chain-fatty-acyl-CoA reductase activity(GO:0050062) |
| 0.1 | 0.9 | GO:0052654 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 0.1 | 0.4 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
| 0.1 | 0.3 | GO:0016531 | copper chaperone activity(GO:0016531) |
| 0.1 | 0.4 | GO:0004090 | carbonyl reductase (NADPH) activity(GO:0004090) |
| 0.1 | 0.7 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
| 0.1 | 0.2 | GO:0003831 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) |
| 0.0 | 0.4 | GO:0034056 | estrogen response element binding(GO:0034056) |
| 0.0 | 0.2 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
| 0.0 | 0.3 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
| 0.0 | 0.6 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
| 0.0 | 0.3 | GO:0035240 | dopamine binding(GO:0035240) |
| 0.0 | 0.2 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 0.0 | 1.1 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.0 | 1.2 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.0 | 0.1 | GO:0003870 | 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749) |
| 0.0 | 0.1 | GO:0017129 | triglyceride binding(GO:0017129) |
| 0.0 | 0.5 | GO:0016896 | exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896) |
| 0.0 | 0.3 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.0 | 0.6 | GO:0017069 | snRNA binding(GO:0017069) |
| 0.0 | 0.1 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
| 0.0 | 0.1 | GO:0052590 | sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591) |
| 0.0 | 0.1 | GO:0005132 | type I interferon receptor binding(GO:0005132) |
| 0.0 | 0.5 | GO:0004623 | phospholipase A2 activity(GO:0004623) |
| 0.0 | 0.1 | GO:0004618 | phosphoglycerate kinase activity(GO:0004618) |
| 0.0 | 0.1 | GO:0061731 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
| 0.0 | 0.1 | GO:0015057 | thrombin receptor activity(GO:0015057) |
| 0.0 | 0.1 | GO:0003829 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829) |
| 0.0 | 0.1 | GO:0047894 | flavonol 3-sulfotransferase activity(GO:0047894) |
| 0.0 | 0.2 | GO:0016565 | obsolete general transcriptional repressor activity(GO:0016565) |
| 0.0 | 0.1 | GO:0033989 | 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) |
| 0.0 | 0.1 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.0 | 0.1 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.0 | 0.2 | GO:0003704 | obsolete specific RNA polymerase II transcription factor activity(GO:0003704) |
| 0.0 | 0.5 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.0 | 0.4 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
