Motif ID: EN2_GBX2_LBX2

Z-value: 1.054

Transcription factors associated with EN2_GBX2_LBX2:

Gene SymbolEntrez IDGene Name
EN2 ENSG00000164778.4 EN2
GBX2 ENSG00000168505.6 GBX2
LBX2 ENSG00000179528.11 LBX2






Network of associatons between targets according to the STRING database.



First level regulatory network of EN2_GBX2_LBX2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_55562479 1.744 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr15_-_55563072 1.614 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A


RAB27A, member RAS oncogene family


chr6_+_26199737 1.403 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chr4_-_105416039 1.341 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr15_-_55562582 1.217 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr7_+_138145076 1.095 ENST00000343526.4
TRIM24
tripartite motif containing 24
chr15_-_37393406 1.064 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2


Meis homeobox 2


chr13_-_41593425 1.036 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr2_-_61697862 0.987 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr6_-_39693111 0.950 ENST00000373215.3
ENST00000538893.1
ENST00000287152.7
ENST00000373216.3
KIF6



kinesin family member 6



chr9_+_2159850 0.909 ENST00000416751.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr6_-_26199499 0.862 ENST00000377831.5
HIST1H3D
histone cluster 1, H3d
chr6_+_135502501 0.852 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB






v-myb avian myeloblastosis viral oncogene homolog






chr6_-_32157947 0.839 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr16_-_29910853 0.754 ENST00000308713.5
SEZ6L2
seizure related 6 homolog (mouse)-like 2
chr6_-_111927062 0.731 ENST00000359831.4
TRAF3IP2
TRAF3 interacting protein 2
chr3_+_167453493 0.621 ENST00000295777.5
ENST00000472747.2
SERPINI1

serpin peptidase inhibitor, clade I (neuroserpin), member 1

chr2_-_242089677 0.609 ENST00000405260.1
PASK
PAS domain containing serine/threonine kinase
chr11_+_67250490 0.599 ENST00000528641.2
ENST00000279146.3
AIP

aryl hydrocarbon receptor interacting protein

chr12_+_28410128 0.596 ENST00000381259.1
ENST00000381256.1
CCDC91

coiled-coil domain containing 91

chr18_+_59000815 0.586 ENST00000262717.4
CDH20
cadherin 20, type 2
chr18_-_31803435 0.585 ENST00000589544.1
ENST00000269185.4
ENST00000261592.5
NOL4


nucleolar protein 4


chr3_-_141747950 0.565 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr18_+_55888767 0.562 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L


neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase


chr11_-_33913708 0.560 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr13_-_36788718 0.535 ENST00000317764.6
ENST00000379881.3
SOHLH2

spermatogenesis and oogenesis specific basic helix-loop-helix 2

chrM_+_12331 0.531 ENST00000361567.2
MT-ND5
mitochondrially encoded NADH dehydrogenase 5
chr1_-_190446759 0.521 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr21_-_43816052 0.500 ENST00000398405.1
TMPRSS3
transmembrane protease, serine 3
chr17_-_39191107 0.496 ENST00000344363.5
KRTAP1-3
keratin associated protein 1-3
chr6_-_26199471 0.485 ENST00000341023.1
HIST1H2AD
histone cluster 1, H2ad
chr10_-_50970322 0.479 ENST00000374103.4
OGDHL
oxoglutarate dehydrogenase-like
chr1_+_179923873 0.475 ENST00000367607.3
ENST00000491495.2
CEP350

centrosomal protein 350kDa

chr3_+_111718173 0.446 ENST00000494932.1
TAGLN3
transgelin 3
chr4_-_39979576 0.445 ENST00000303538.8
ENST00000503396.1
PDS5A

PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)

chr17_+_47448102 0.442 ENST00000576461.1
RP11-81K2.1
Uncharacterized protein
chr6_-_26250835 0.426 ENST00000446824.2
HIST1H3F
histone cluster 1, H3f
chr20_-_50722183 0.413 ENST00000371523.4
ZFP64
ZFP64 zinc finger protein
chr7_+_77428066 0.412 ENST00000422959.2
ENST00000307305.8
ENST00000424760.1
PHTF2


putative homeodomain transcription factor 2


chr10_-_50970382 0.411 ENST00000419399.1
ENST00000432695.1
OGDHL

oxoglutarate dehydrogenase-like

chr7_+_77428149 0.374 ENST00000415251.2
ENST00000275575.7
PHTF2

putative homeodomain transcription factor 2

chr1_+_101003687 0.373 ENST00000315033.4
GPR88
G protein-coupled receptor 88
chr8_+_50824233 0.356 ENST00000522124.1
SNTG1
syntrophin, gamma 1
chr2_+_86668464 0.337 ENST00000409064.1
KDM3A
lysine (K)-specific demethylase 3A
chr12_-_28123206 0.336 ENST00000542963.1
ENST00000535992.1
PTHLH

parathyroid hormone-like hormone

chr18_+_32173276 0.312 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA








dystrobrevin, alpha








chr2_+_65216462 0.310 ENST00000234256.3
SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr14_+_32798462 0.310 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr14_+_32798547 0.307 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6


A kinase (PRKA) anchor protein 6


chr2_-_77749474 0.305 ENST00000409093.1
ENST00000409088.3
LRRTM4

leucine rich repeat transmembrane neuronal 4

chr12_-_28122980 0.292 ENST00000395868.3
ENST00000534890.1
PTHLH

parathyroid hormone-like hormone

chr12_-_14133053 0.283 ENST00000609686.1
GRIN2B
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
chr4_-_116034979 0.282 ENST00000264363.2
NDST4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr1_+_171227069 0.278 ENST00000354841.4
FMO1
flavin containing monooxygenase 1
chr7_+_100136811 0.277 ENST00000300176.4
ENST00000262935.4
AGFG2

ArfGAP with FG repeats 2

chr14_-_51027838 0.275 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr1_-_156399184 0.272 ENST00000368243.1
ENST00000357975.4
ENST00000310027.5
ENST00000400991.2
C1orf61



chromosome 1 open reading frame 61



chr19_+_48949030 0.270 ENST00000253237.5
GRWD1
glutamate-rich WD repeat containing 1
chr15_+_58430368 0.268 ENST00000558772.1
ENST00000219919.4
AQP9

aquaporin 9

chr6_-_26032288 0.255 ENST00000244661.2
HIST1H3B
histone cluster 1, H3b
chr2_+_196313239 0.250 ENST00000413290.1
AC064834.1
AC064834.1
chr3_+_115342349 0.250 ENST00000393780.3
GAP43
growth associated protein 43
chr19_-_51522955 0.250 ENST00000358789.3
KLK10
kallikrein-related peptidase 10
chr17_-_9929581 0.248 ENST00000437099.2
ENST00000396115.2
GAS7

growth arrest-specific 7

chr18_-_31803169 0.246 ENST00000590712.1
NOL4
nucleolar protein 4
chr12_+_52695617 0.243 ENST00000293525.5
KRT86
keratin 86
chr1_+_62901968 0.234 ENST00000452143.1
ENST00000442679.1
ENST00000371146.1
USP1


ubiquitin specific peptidase 1


chr1_-_152386732 0.231 ENST00000271835.3
CRNN
cornulin
chr11_+_75526212 0.225 ENST00000356136.3
UVRAG
UV radiation resistance associated
chr6_-_76203345 0.222 ENST00000393004.2
FILIP1
filamin A interacting protein 1
chr1_+_110881945 0.220 ENST00000602849.1
ENST00000487146.2
RBM15

RNA binding motif protein 15

chr12_-_52828147 0.219 ENST00000252245.5
KRT75
keratin 75
chr6_+_34204642 0.212 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1




high mobility group AT-hook 1




chr10_-_48416849 0.210 ENST00000249598.1
GDF2
growth differentiation factor 2
chr1_+_214161272 0.209 ENST00000498508.2
ENST00000366958.4
PROX1

prospero homeobox 1

chrX_+_135730297 0.208 ENST00000370629.2
CD40LG
CD40 ligand
chr17_-_74163159 0.207 ENST00000591615.1
RNF157
ring finger protein 157
chr19_-_59084647 0.206 ENST00000594234.1
ENST00000596039.1
MZF1

myeloid zinc finger 1

chr2_+_171034646 0.204 ENST00000409044.3
ENST00000408978.4
MYO3B

myosin IIIB

chr2_+_47630108 0.198 ENST00000233146.2
ENST00000454849.1
ENST00000543555.1
MSH2


mutS homolog 2


chr15_+_58430567 0.193 ENST00000536493.1
AQP9
aquaporin 9
chr14_+_72052983 0.190 ENST00000358550.2
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr9_+_136501478 0.186 ENST00000393056.2
ENST00000263611.2
DBH

dopamine beta-hydroxylase (dopamine beta-monooxygenase)

chrX_-_53461305 0.186 ENST00000168216.6
HSD17B10
hydroxysteroid (17-beta) dehydrogenase 10
chr4_-_26492076 0.185 ENST00000295589.3
CCKAR
cholecystokinin A receptor
chr4_-_120243545 0.184 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chrX_-_53461288 0.183 ENST00000375298.4
ENST00000375304.5
HSD17B10

hydroxysteroid (17-beta) dehydrogenase 10

chr2_+_47630255 0.181 ENST00000406134.1
MSH2
mutS homolog 2
chr7_-_25268104 0.176 ENST00000222674.2
NPVF
neuropeptide VF precursor
chr19_+_4007644 0.176 ENST00000262971.2
PIAS4
protein inhibitor of activated STAT, 4
chr17_-_48785216 0.174 ENST00000285243.6
ANKRD40
ankyrin repeat domain 40
chr8_+_105235572 0.170 ENST00000523362.1
RIMS2
regulating synaptic membrane exocytosis 2
chr12_+_7014064 0.169 ENST00000443597.2
LRRC23
leucine rich repeat containing 23
chr7_+_127292234 0.165 ENST00000354725.3
SND1
staphylococcal nuclease and tudor domain containing 1
chr16_+_103816 0.162 ENST00000383018.3
ENST00000417493.1
SNRNP25

small nuclear ribonucleoprotein 25kDa (U11/U12)

chr7_+_74072288 0.162 ENST00000443166.1
GTF2I
general transcription factor IIi
chr9_-_116840728 0.161 ENST00000265132.3
AMBP
alpha-1-microglobulin/bikunin precursor
chr19_-_19302931 0.152 ENST00000444486.3
ENST00000514819.3
ENST00000162023.5
ENST00000585679.1
MEF2BNB-MEF2B

MEF2B
MEF2BNB
MEF2BNB-MEF2B readthrough

myocyte enhancer factor 2B
MEF2B neighbor
chr15_-_64673665 0.150 ENST00000300035.4
KIAA0101
KIAA0101
chr20_-_18447667 0.149 ENST00000262547.5
ENST00000329494.5
ENST00000357236.4
DZANK1


double zinc ribbon and ankyrin repeat domains 1


chr17_-_10017864 0.148 ENST00000323816.4
GAS7
growth arrest-specific 7
chr8_-_42234745 0.144 ENST00000220812.2
DKK4
dickkopf WNT signaling pathway inhibitor 4
chr15_-_64673630 0.134 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101


KIAA0101


chr11_-_71823715 0.126 ENST00000545944.1
ENST00000502597.2
ANAPC15

anaphase promoting complex subunit 15

chr12_+_53662073 0.124 ENST00000553219.1
ENST00000257934.4
ESPL1

extra spindle pole bodies homolog 1 (S. cerevisiae)

chr3_-_195538728 0.122 ENST00000349607.4
ENST00000346145.4
MUC4

mucin 4, cell surface associated

chr11_-_71823796 0.120 ENST00000545680.1
ENST00000543587.1
ENST00000538393.1
ENST00000535234.1
ENST00000227618.4
ENST00000535503.1
ANAPC15





anaphase promoting complex subunit 15





chr15_+_40733387 0.118 ENST00000416165.1
BAHD1
bromo adjacent homology domain containing 1
chr9_+_80912059 0.117 ENST00000347159.2
ENST00000376588.3
PSAT1

phosphoserine aminotransferase 1

chr12_-_53171128 0.116 ENST00000332411.2
KRT76
keratin 76
chr4_-_174255536 0.115 ENST00000446922.2
HMGB2
high mobility group box 2
chr19_+_11485333 0.114 ENST00000312423.2
SWSAP1
SWIM-type zinc finger 7 associated protein 1
chr4_-_89205879 0.103 ENST00000608933.1
ENST00000315194.4
ENST00000514204.1
PPM1K


protein phosphatase, Mg2+/Mn2+ dependent, 1K


chr3_+_152879985 0.101 ENST00000323534.2
RAP2B
RAP2B, member of RAS oncogene family
chr12_-_14849470 0.100 ENST00000261170.3
GUCY2C
guanylate cyclase 2C (heat stable enterotoxin receptor)
chr14_-_104181771 0.100 ENST00000554913.1
ENST00000554974.1
ENST00000553361.1
ENST00000555055.1
ENST00000555964.1
ENST00000556682.1
ENST00000445556.1
ENST00000553332.1
ENST00000352127.7
XRCC3








X-ray repair complementing defective repair in Chinese hamster cells 3








chr9_+_12693336 0.097 ENST00000381137.2
ENST00000388918.5
TYRP1

tyrosinase-related protein 1

chr3_-_52090461 0.093 ENST00000296483.6
ENST00000495880.1
DUSP7

dual specificity phosphatase 7

chr12_+_53662110 0.091 ENST00000552462.1
ESPL1
extra spindle pole bodies homolog 1 (S. cerevisiae)
chr3_+_173116225 0.090 ENST00000457714.1
NLGN1
neuroligin 1
chr4_-_174256276 0.089 ENST00000296503.5
HMGB2
high mobility group box 2
chr3_-_195538760 0.088 ENST00000475231.1
MUC4
mucin 4, cell surface associated
chr1_+_153747746 0.086 ENST00000368661.3
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr3_+_111718036 0.084 ENST00000455401.2
TAGLN3
transgelin 3
chr2_-_163008903 0.084 ENST00000418842.2
ENST00000375497.3
GCG

glucagon

chr1_+_62439037 0.083 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr19_+_51728316 0.081 ENST00000436584.2
ENST00000421133.2
ENST00000391796.3
ENST00000262262.4
CD33



CD33 molecule



chr6_-_31088214 0.076 ENST00000376288.2
CDSN
corneodesmosin
chr11_-_71823266 0.075 ENST00000538919.1
ENST00000539395.1
ENST00000542531.1
ANAPC15


anaphase promoting complex subunit 15


chr5_-_95297678 0.074 ENST00000237853.4
ELL2
elongation factor, RNA polymerase II, 2
chr17_-_64225508 0.074 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr5_+_179159813 0.073 ENST00000292599.3
MAML1
mastermind-like 1 (Drosophila)
chr6_+_26020672 0.072 ENST00000357647.3
HIST1H3A
histone cluster 1, H3a
chr19_-_14064114 0.070 ENST00000585607.1
ENST00000538517.2
ENST00000587458.1
ENST00000538371.2
PODNL1



podocan-like 1



chr12_+_7013897 0.069 ENST00000007969.8
ENST00000323702.5
LRRC23

leucine rich repeat containing 23

chr1_+_160160346 0.067 ENST00000368078.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr5_+_66300446 0.066 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr1_+_160160283 0.057 ENST00000368079.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr3_+_133292759 0.056 ENST00000431519.2
CDV3
CDV3 homolog (mouse)
chr8_-_25281747 0.046 ENST00000421054.2
GNRH1
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr16_+_53164833 0.043 ENST00000564845.1
CHD9
chromodomain helicase DNA binding protein 9
chr7_-_73038867 0.042 ENST00000313375.3
ENST00000354613.1
ENST00000395189.1
ENST00000453275.1
MLXIPL



MLX interacting protein-like



chr8_+_24298597 0.041 ENST00000380789.1
ADAM7
ADAM metallopeptidase domain 7
chr15_-_31393910 0.040 ENST00000397795.2
ENST00000256552.6
ENST00000559179.1
TRPM1


transient receptor potential cation channel, subfamily M, member 1


chr12_+_7014126 0.040 ENST00000415834.1
ENST00000436789.1
LRRC23

leucine rich repeat containing 23

chr4_-_89205705 0.039 ENST00000295908.7
ENST00000510548.2
ENST00000508256.1
PPM1K


protein phosphatase, Mg2+/Mn2+ dependent, 1K


chr15_+_89631647 0.037 ENST00000569550.1
ENST00000565066.1
ENST00000565973.1
ABHD2


abhydrolase domain containing 2


chr6_+_131571535 0.035 ENST00000474850.2
AKAP7
A kinase (PRKA) anchor protein 7
chr17_+_7792101 0.033 ENST00000358181.4
ENST00000330494.7
CHD3

chromodomain helicase DNA binding protein 3

chr9_+_116225999 0.031 ENST00000317613.6
RGS3
regulator of G-protein signaling 3
chr17_-_8093471 0.031 ENST00000389017.4
C17orf59
chromosome 17 open reading frame 59
chr17_-_47045949 0.030 ENST00000357424.2
GIP
gastric inhibitory polypeptide
chr3_-_119813264 0.030 ENST00000264235.8
GSK3B
glycogen synthase kinase 3 beta
chr8_+_24298531 0.025 ENST00000175238.6
ADAM7
ADAM metallopeptidase domain 7
chr16_+_69345243 0.021 ENST00000254950.11
VPS4A
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr5_+_145826867 0.018 ENST00000296702.5
ENST00000394421.2
TCERG1

transcription elongation regulator 1

chr6_-_161695074 0.015 ENST00000457520.2
ENST00000366906.5
ENST00000320285.4
AGPAT4


1-acylglycerol-3-phosphate O-acyltransferase 4


chr1_-_23670752 0.015 ENST00000302271.6
ENST00000426846.2
ENST00000427764.2
ENST00000606561.1
ENST00000374616.3
HNRNPR




heterogeneous nuclear ribonucleoprotein R




chr12_-_101604185 0.013 ENST00000536262.2
SLC5A8
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
chr6_-_31782813 0.012 ENST00000375654.4
HSPA1L
heat shock 70kDa protein 1-like
chr3_+_130569429 0.010 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1



ATPase, Ca++ transporting, type 2C, member 1



chr7_-_73038822 0.006 ENST00000414749.2
ENST00000429400.2
ENST00000434326.1
MLXIPL


MLX interacting protein-like


chr19_-_41870026 0.006 ENST00000243578.3
B9D2
B9 protein domain 2

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.6 GO:0043316 natural killer cell activation involved in immune response(GO:0002323) cytotoxic T cell degranulation(GO:0043316) natural killer cell degranulation(GO:0043320)
0.4 1.1 GO:1901419 regulation of response to alcohol(GO:1901419)
0.2 1.3 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.2 0.6 GO:0060649 nipple development(GO:0060618) mammary gland bud elongation(GO:0060649) nipple morphogenesis(GO:0060658) nipple sheath formation(GO:0060659)
0.2 1.1 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 0.3 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.1 0.2 GO:0045750 obsolete positive regulation of S phase of mitotic cell cycle(GO:0045750)
0.1 0.3 GO:0032328 alanine transport(GO:0032328)
0.1 0.4 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520) negative regulation of meiotic nuclear division(GO:0045835) regulation of meiosis I(GO:0060631)
0.1 0.5 GO:0015722 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855)
0.1 1.0 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.6 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 0.3 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.6 GO:0022417 protein maturation by protein folding(GO:0022417)
0.1 0.2 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
0.1 0.2 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.2 GO:1904037 positive regulation of epithelial cell apoptotic process(GO:1904037) positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.3 GO:0060992 response to fungicide(GO:0060992)
0.0 0.2 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 0.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.4 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.1 GO:0042816 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.8 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.3 GO:0060998 regulation of dendritic spine development(GO:0060998)
0.0 2.0 GO:0031497 chromatin assembly(GO:0031497)
0.0 0.1 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.0 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.0 0.0 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.0 0.1 GO:0032099 negative regulation of appetite(GO:0032099)
0.0 0.2 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0 0.9 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.2 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.2 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.6 GO:0007422 peripheral nervous system development(GO:0007422)
0.0 0.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.4 GO:0032302 MutSbeta complex(GO:0032302)
0.1 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.3 GO:0016600 flotillin complex(GO:0016600) synaptic cleft(GO:0043083)
0.1 0.9 GO:0071778 obsolete WINAC complex(GO:0071778)
0.1 4.8 GO:0030667 secretory granule membrane(GO:0030667)
0.0 1.9 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 1.1 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.7 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 1.0 GO:0016363 nuclear matrix(GO:0016363)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.6 GO:0031489 myosin V binding(GO:0031489)
0.2 0.9 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.4 GO:0000404 heteroduplex DNA loop binding(GO:0000404) double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.1 1.1 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.5 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.3 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.6 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.2 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.1 0.2 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0019862 IgA binding(GO:0019862)
0.0 0.2 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.7 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.4 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 1.2 GO:0004221 obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0 0.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 1.3 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.2 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.9 GO:0016566 obsolete specific transcriptional repressor activity(GO:0016566)
0.0 0.9 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.0 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.5 GO:0050136 NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)