Motif ID: EPAS1_BCL3
Z-value: 2.040
Transcription factors associated with EPAS1_BCL3:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
BCL3 | ENSG00000069399.8 | BCL3 |
EPAS1 | ENSG00000116016.9 | EPAS1 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.7 | 5.1 | GO:0010902 | positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902) positive regulation of phospholipid catabolic process(GO:0060697) |
1.3 | 7.5 | GO:0046882 | negative regulation of gonadotropin secretion(GO:0032277) negative regulation of follicle-stimulating hormone secretion(GO:0046882) |
0.9 | 3.7 | GO:0045048 | protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816) |
0.9 | 2.8 | GO:0002514 | B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663) |
0.7 | 3.6 | GO:0006927 | obsolete transformed cell apoptotic process(GO:0006927) |
0.7 | 4.1 | GO:0060710 | chorio-allantoic fusion(GO:0060710) |
0.7 | 2.0 | GO:0010757 | chronological cell aging(GO:0001300) negative regulation of plasminogen activation(GO:0010757) negative regulation of cell adhesion mediated by integrin(GO:0033629) |
0.7 | 3.3 | GO:1901031 | regulation of cellular response to oxidative stress(GO:1900407) regulation of response to reactive oxygen species(GO:1901031) regulation of response to oxidative stress(GO:1902882) |
0.6 | 1.9 | GO:0001907 | cytolysis by symbiont of host cells(GO:0001897) killing by symbiont of host cells(GO:0001907) hemolysis by symbiont of host erythrocytes(GO:0019836) disruption by symbiont of host cell(GO:0044004) hemolysis in other organism(GO:0044179) positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010) cytolysis in other organism(GO:0051715) cytolysis in other organism involved in symbiotic interaction(GO:0051801) hemolysis in other organism involved in symbiotic interaction(GO:0052331) |
0.6 | 7.0 | GO:0060762 | regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) |
0.5 | 2.2 | GO:0034442 | plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161) |
0.5 | 1.6 | GO:0002374 | cytokine secretion involved in immune response(GO:0002374) regulation of cytokine secretion involved in immune response(GO:0002739) negative regulation of cytokine secretion involved in immune response(GO:0002740) regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910) |
0.5 | 1.6 | GO:0002887 | wound healing involved in inflammatory response(GO:0002246) negative regulation of myeloid leukocyte mediated immunity(GO:0002887) heme oxidation(GO:0006788) negative regulation of leukocyte degranulation(GO:0043301) inflammatory response to wounding(GO:0090594) |
0.5 | 1.5 | GO:0048389 | intermediate mesoderm development(GO:0048389) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) bud dilation involved in lung branching(GO:0060503) branch elongation involved in ureteric bud branching(GO:0060681) regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) pulmonary artery morphogenesis(GO:0061156) cell proliferation involved in mesonephros development(GO:0061209) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) negative regulation of mesonephros development(GO:0061218) pattern specification involved in mesonephros development(GO:0061227) renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) BMP signaling pathway involved in nephric duct formation(GO:0071893) glomerular visceral epithelial cell development(GO:0072015) comma-shaped body morphogenesis(GO:0072049) regulation of branch elongation involved in ureteric bud branching(GO:0072095) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in kidney development(GO:0072098) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) glomerulus morphogenesis(GO:0072102) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104) mesenchymal cell proliferation involved in ureteric bud development(GO:0072138) nephric duct formation(GO:0072179) ureter urothelium development(GO:0072190) ureter epithelial cell differentiation(GO:0072192) ureter morphogenesis(GO:0072197) metanephric comma-shaped body morphogenesis(GO:0072278) glomerular epithelial cell development(GO:0072310) negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007) |
0.5 | 1.5 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
0.4 | 1.3 | GO:1990170 | detoxification of cadmium ion(GO:0071585) stress response to cadmium ion(GO:1990170) |
0.4 | 1.9 | GO:0007614 | short-term memory(GO:0007614) |
0.3 | 2.0 | GO:0032460 | negative regulation of protein oligomerization(GO:0032460) negative regulation of protein homooligomerization(GO:0032463) |
0.3 | 1.6 | GO:0060662 | tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662) |
0.3 | 0.9 | GO:1904729 | regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729) |
0.3 | 1.2 | GO:0030037 | actin filament reorganization involved in cell cycle(GO:0030037) actin filament reorganization(GO:0090527) |
0.3 | 1.1 | GO:0034959 | neuropeptide catabolic process(GO:0010813) substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959) |
0.3 | 2.6 | GO:0055003 | cardiac myofibril assembly(GO:0055003) |
0.3 | 3.6 | GO:0001945 | lymph vessel development(GO:0001945) |
0.3 | 3.3 | GO:1904893 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
0.2 | 0.7 | GO:0070672 | response to interleukin-15(GO:0070672) |
0.2 | 3.7 | GO:0034446 | substrate adhesion-dependent cell spreading(GO:0034446) |
0.2 | 3.2 | GO:0032331 | negative regulation of chondrocyte differentiation(GO:0032331) |
0.2 | 0.7 | GO:0048319 | axial mesoderm morphogenesis(GO:0048319) |
0.2 | 0.7 | GO:0048861 | leukemia inhibitory factor signaling pathway(GO:0048861) |
0.2 | 1.1 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
0.2 | 0.4 | GO:0060394 | negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394) |
0.2 | 0.8 | GO:0031340 | positive regulation of vesicle fusion(GO:0031340) |
0.2 | 0.2 | GO:0060677 | ureteric bud elongation(GO:0060677) |
0.2 | 0.4 | GO:0002890 | negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890) |
0.2 | 0.3 | GO:0060214 | endocardium formation(GO:0060214) |
0.1 | 1.3 | GO:0006546 | glycine catabolic process(GO:0006546) |
0.1 | 0.8 | GO:0006562 | proline catabolic process(GO:0006562) |
0.1 | 1.5 | GO:0046628 | positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078) |
0.1 | 0.4 | GO:0045618 | positive regulation of keratinocyte differentiation(GO:0045618) |
0.1 | 0.4 | GO:0009635 | response to herbicide(GO:0009635) |
0.1 | 0.4 | GO:0002575 | basophil chemotaxis(GO:0002575) |
0.1 | 0.4 | GO:0001830 | trophectodermal cell fate commitment(GO:0001830) |
0.1 | 0.6 | GO:0070245 | positive regulation of thymocyte apoptotic process(GO:0070245) |
0.1 | 0.3 | GO:0050758 | thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760) |
0.1 | 0.7 | GO:0015886 | heme transport(GO:0015886) |
0.1 | 0.4 | GO:0072385 | minus-end-directed organelle transport along microtubule(GO:0072385) |
0.1 | 0.8 | GO:0071731 | response to nitric oxide(GO:0071731) |
0.1 | 0.3 | GO:0008298 | intracellular mRNA localization(GO:0008298) |
0.1 | 0.4 | GO:0009109 | coenzyme catabolic process(GO:0009109) |
0.1 | 8.0 | GO:0031668 | cellular response to extracellular stimulus(GO:0031668) |
0.1 | 0.5 | GO:0060164 | regulation of timing of neuron differentiation(GO:0060164) |
0.1 | 1.4 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
0.1 | 0.7 | GO:0035058 | nonmotile primary cilium assembly(GO:0035058) |
0.1 | 1.9 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
0.1 | 1.8 | GO:0003407 | neural retina development(GO:0003407) |
0.1 | 3.9 | GO:0030520 | intracellular estrogen receptor signaling pathway(GO:0030520) |
0.1 | 0.7 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
0.1 | 1.6 | GO:0043586 | tongue development(GO:0043586) |
0.1 | 0.2 | GO:0048520 | positive regulation of behavior(GO:0048520) |
0.1 | 0.4 | GO:0045945 | positive regulation of transcription from RNA polymerase III promoter(GO:0045945) |
0.1 | 0.5 | GO:0002051 | osteoblast fate commitment(GO:0002051) |
0.1 | 0.9 | GO:0051014 | actin filament severing(GO:0051014) |
0.1 | 0.3 | GO:0002158 | osteoclast proliferation(GO:0002158) |
0.1 | 0.3 | GO:0009153 | purine deoxyribonucleotide biosynthetic process(GO:0009153) |
0.1 | 0.3 | GO:0045662 | negative regulation of myoblast differentiation(GO:0045662) |
0.1 | 0.4 | GO:0035444 | nickel cation transport(GO:0015675) vanadium ion transport(GO:0015676) ferrous iron transport(GO:0015684) lead ion transport(GO:0015692) nickel cation transmembrane transport(GO:0035444) ferrous iron import(GO:0070627) iron ion import(GO:0097286) |
0.1 | 0.4 | GO:0009629 | response to gravity(GO:0009629) |
0.1 | 0.2 | GO:0035120 | post-embryonic appendage morphogenesis(GO:0035120) |
0.1 | 5.6 | GO:0006821 | chloride transport(GO:0006821) |
0.1 | 0.2 | GO:0018874 | benzoate metabolic process(GO:0018874) |
0.1 | 0.1 | GO:0090206 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
0.1 | 0.4 | GO:0002220 | innate immune response activating cell surface receptor signaling pathway(GO:0002220) |
0.1 | 1.4 | GO:0009086 | methionine biosynthetic process(GO:0009086) |
0.1 | 0.3 | GO:0031017 | exocrine pancreas development(GO:0031017) |
0.1 | 0.2 | GO:0045760 | positive regulation of action potential(GO:0045760) |
0.1 | 0.4 | GO:0009450 | gamma-aminobutyric acid catabolic process(GO:0009450) |
0.1 | 0.5 | GO:0035313 | wound healing, spreading of epidermal cells(GO:0035313) wound healing, spreading of cells(GO:0044319) epiboly(GO:0090504) epiboly involved in wound healing(GO:0090505) |
0.1 | 1.0 | GO:0006750 | glutathione biosynthetic process(GO:0006750) |
0.1 | 2.1 | GO:0007566 | embryo implantation(GO:0007566) |
0.1 | 2.1 | GO:0046847 | filopodium assembly(GO:0046847) |
0.1 | 0.1 | GO:0007403 | glial cell fate determination(GO:0007403) |
0.1 | 0.3 | GO:0002052 | positive regulation of neuroblast proliferation(GO:0002052) |
0.1 | 0.9 | GO:0008635 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635) |
0.1 | 0.4 | GO:0030277 | epithelial structure maintenance(GO:0010669) maintenance of gastrointestinal epithelium(GO:0030277) |
0.1 | 0.6 | GO:0019885 | antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885) |
0.1 | 1.9 | GO:0015914 | phospholipid transport(GO:0015914) |
0.1 | 5.6 | GO:0007565 | female pregnancy(GO:0007565) |
0.1 | 2.3 | GO:0045576 | mast cell activation(GO:0045576) |
0.1 | 1.7 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
0.0 | 0.1 | GO:0010727 | negative regulation of hydrogen peroxide metabolic process(GO:0010727) |
0.0 | 2.7 | GO:0032526 | response to retinoic acid(GO:0032526) |
0.0 | 2.7 | GO:0055088 | lipid homeostasis(GO:0055088) |
0.0 | 0.5 | GO:0000301 | retrograde transport, vesicle recycling within Golgi(GO:0000301) |
0.0 | 0.1 | GO:0050917 | sensory perception of umami taste(GO:0050917) |
0.0 | 0.2 | GO:0032465 | regulation of cytokinesis(GO:0032465) |
0.0 | 2.8 | GO:0007569 | cell aging(GO:0007569) |
0.0 | 0.3 | GO:0090205 | positive regulation of cholesterol biosynthetic process(GO:0045542) positive regulation of cholesterol metabolic process(GO:0090205) |
0.0 | 0.2 | GO:0050968 | detection of chemical stimulus involved in sensory perception of pain(GO:0050968) |
0.0 | 0.1 | GO:0072334 | UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481) nucleotide transmembrane transport(GO:1901679) |
0.0 | 0.4 | GO:0051016 | barbed-end actin filament capping(GO:0051016) |
0.0 | 0.1 | GO:0021670 | lateral ventricle development(GO:0021670) |
0.0 | 0.8 | GO:0009812 | flavonoid metabolic process(GO:0009812) |
0.0 | 0.3 | GO:0042491 | auditory receptor cell differentiation(GO:0042491) |
0.0 | 1.8 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
0.0 | 0.3 | GO:0097384 | cellular lipid biosynthetic process(GO:0097384) |
0.0 | 0.2 | GO:0035246 | peptidyl-arginine N-methylation(GO:0035246) |
0.0 | 0.1 | GO:0048702 | embryonic neurocranium morphogenesis(GO:0048702) |
0.0 | 0.1 | GO:0050653 | chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653) |
0.0 | 0.2 | GO:0008653 | lipopolysaccharide metabolic process(GO:0008653) |
0.0 | 0.1 | GO:0001880 | Mullerian duct regression(GO:0001880) |
0.0 | 0.1 | GO:0033687 | osteoblast proliferation(GO:0033687) |
0.0 | 0.1 | GO:0007252 | I-kappaB phosphorylation(GO:0007252) |
0.0 | 0.2 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
0.0 | 0.1 | GO:0006540 | glutamate decarboxylation to succinate(GO:0006540) |
0.0 | 0.7 | GO:0046470 | phosphatidylcholine metabolic process(GO:0046470) |
0.0 | 0.1 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
0.0 | 0.1 | GO:0014912 | negative regulation of smooth muscle cell migration(GO:0014912) |
0.0 | 1.0 | GO:0007585 | respiratory gaseous exchange(GO:0007585) |
0.0 | 0.1 | GO:0007210 | serotonin receptor signaling pathway(GO:0007210) |
0.0 | 0.2 | GO:0007423 | sensory organ development(GO:0007423) |
0.0 | 1.2 | GO:0009791 | post-embryonic development(GO:0009791) |
0.0 | 3.7 | GO:0006869 | lipid transport(GO:0006869) |
0.0 | 0.1 | GO:0030147 | obsolete natriuresis(GO:0030147) |
0.0 | 0.8 | GO:0007189 | adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189) |
0.0 | 0.6 | GO:0006921 | cellular component disassembly involved in execution phase of apoptosis(GO:0006921) execution phase of apoptosis(GO:0097194) |
0.0 | 0.0 | GO:0032328 | alanine transport(GO:0032328) |
0.0 | 0.1 | GO:0070309 | lens fiber cell morphogenesis(GO:0070309) |
0.0 | 0.1 | GO:0006295 | nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295) |
0.0 | 0.2 | GO:0045070 | positive regulation of viral genome replication(GO:0045070) |
0.0 | 1.4 | GO:0007229 | integrin-mediated signaling pathway(GO:0007229) |
0.0 | 0.3 | GO:0042994 | cytoplasmic sequestering of transcription factor(GO:0042994) |
0.0 | 0.1 | GO:0001941 | postsynaptic membrane organization(GO:0001941) |
0.0 | 0.4 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
0.0 | 0.1 | GO:0006069 | ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069) |
0.0 | 0.2 | GO:0019228 | neuronal action potential(GO:0019228) |
0.0 | 0.4 | GO:0008154 | actin polymerization or depolymerization(GO:0008154) |
0.0 | 0.1 | GO:0046069 | cGMP catabolic process(GO:0046069) |
0.0 | 0.4 | GO:0090630 | activation of GTPase activity(GO:0090630) |
0.0 | 0.2 | GO:0043113 | receptor clustering(GO:0043113) |
0.0 | 0.1 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
0.0 | 0.1 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
0.0 | 0.1 | GO:0046642 | negative regulation of alpha-beta T cell proliferation(GO:0046642) |
0.0 | 0.1 | GO:0070120 | ciliary neurotrophic factor-mediated signaling pathway(GO:0070120) |
0.0 | 0.3 | GO:0007263 | nitric oxide mediated signal transduction(GO:0007263) |
0.0 | 1.0 | GO:0008064 | regulation of actin polymerization or depolymerization(GO:0008064) |
0.0 | 0.4 | GO:0051789 | obsolete response to protein(GO:0051789) |
0.0 | 0.2 | GO:0007044 | cell-substrate junction assembly(GO:0007044) |
0.0 | 0.0 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
0.0 | 0.1 | GO:0001539 | cilium or flagellum-dependent cell motility(GO:0001539) |
0.0 | 0.0 | GO:0045601 | regulation of endothelial cell differentiation(GO:0045601) |
0.0 | 0.4 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
0.0 | 0.3 | GO:0015949 | nucleobase-containing small molecule interconversion(GO:0015949) |
0.0 | 0.2 | GO:0006783 | heme biosynthetic process(GO:0006783) |
0.0 | 0.3 | GO:0005980 | glycogen catabolic process(GO:0005980) |
0.0 | 0.0 | GO:0043030 | regulation of macrophage activation(GO:0043030) |
0.0 | 0.0 | GO:0001507 | acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581) |
0.0 | 0.1 | GO:0006198 | cAMP catabolic process(GO:0006198) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 3.7 | GO:0005607 | laminin-2 complex(GO:0005607) |
0.9 | 3.7 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
0.7 | 5.1 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
0.6 | 2.4 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
0.5 | 5.8 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
0.5 | 2.8 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
0.4 | 1.4 | GO:0005955 | calcineurin complex(GO:0005955) |
0.3 | 0.9 | GO:0071953 | elastic fiber(GO:0071953) |
0.3 | 1.1 | GO:0031310 | intrinsic component of endosome membrane(GO:0031302) intrinsic component of vacuolar membrane(GO:0031310) |
0.2 | 0.7 | GO:0005900 | oncostatin-M receptor complex(GO:0005900) |
0.2 | 2.1 | GO:0031430 | M band(GO:0031430) |
0.2 | 0.5 | GO:0005588 | collagen type V trimer(GO:0005588) |
0.2 | 0.5 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
0.1 | 0.4 | GO:0043512 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
0.1 | 0.5 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
0.1 | 1.3 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
0.1 | 0.4 | GO:0035189 | Rb-E2F complex(GO:0035189) |
0.1 | 0.4 | GO:0032144 | 4-aminobutyrate transaminase complex(GO:0032144) |
0.1 | 0.4 | GO:0070826 | paraferritin complex(GO:0070826) |
0.1 | 0.7 | GO:0034464 | BBSome(GO:0034464) |
0.1 | 5.7 | GO:0034707 | chloride channel complex(GO:0034707) |
0.1 | 0.7 | GO:0030673 | axolemma(GO:0030673) |
0.1 | 1.1 | GO:0034361 | very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385) |
0.1 | 0.6 | GO:0016461 | unconventional myosin complex(GO:0016461) |
0.1 | 0.3 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
0.0 | 4.1 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
0.0 | 1.7 | GO:0016328 | lateral plasma membrane(GO:0016328) |
0.0 | 0.2 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
0.0 | 3.1 | GO:0031902 | late endosome membrane(GO:0031902) |
0.0 | 0.5 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
0.0 | 0.1 | GO:0033268 | node of Ranvier(GO:0033268) |
0.0 | 1.6 | GO:0098636 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
0.0 | 0.6 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
0.0 | 0.2 | GO:0060201 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
0.0 | 0.3 | GO:0000109 | nucleotide-excision repair complex(GO:0000109) |
0.0 | 0.3 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.0 | 0.1 | GO:0036125 | mitochondrial fatty acid beta-oxidation multienzyme complex(GO:0016507) fatty acid beta-oxidation multienzyme complex(GO:0036125) |
0.0 | 0.8 | GO:0000299 | obsolete integral to membrane of membrane fraction(GO:0000299) |
0.0 | 0.2 | GO:0016012 | dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012) |
0.0 | 0.1 | GO:0045298 | tubulin complex(GO:0045298) |
0.0 | 0.4 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.0 | 5.9 | GO:0005912 | adherens junction(GO:0005912) |
0.0 | 3.2 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
0.0 | 0.2 | GO:0042824 | MHC class I peptide loading complex(GO:0042824) |
0.0 | 0.4 | GO:0005811 | lipid particle(GO:0005811) |
0.0 | 0.1 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
0.0 | 0.3 | GO:0005849 | mRNA cleavage factor complex(GO:0005849) |
0.0 | 0.3 | GO:0090568 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568) |
0.0 | 0.5 | GO:0005637 | nuclear inner membrane(GO:0005637) |
0.0 | 0.4 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
0.0 | 1.5 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
0.0 | 0.1 | GO:0033179 | proton-transporting V-type ATPase, V0 domain(GO:0033179) |
0.0 | 2.4 | GO:0019898 | extrinsic component of membrane(GO:0019898) |
0.0 | 0.2 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
0.0 | 0.5 | GO:0005640 | nuclear outer membrane(GO:0005640) |
0.0 | 0.1 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
0.0 | 0.4 | GO:0031519 | PcG protein complex(GO:0031519) |
0.0 | 0.2 | GO:0010369 | chromocenter(GO:0010369) |
0.0 | 0.2 | GO:0042588 | zymogen granule(GO:0042588) |
0.0 | 31.7 | GO:0005576 | extracellular region(GO:0005576) |
0.0 | 1.1 | GO:0030426 | growth cone(GO:0030426) |
0.0 | 0.0 | GO:0060170 | ciliary membrane(GO:0060170) |
0.0 | 0.3 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
0.0 | 0.9 | GO:0005905 | clathrin-coated pit(GO:0005905) |
0.0 | 0.4 | GO:0042641 | actomyosin(GO:0042641) |
0.0 | 0.8 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
0.0 | 0.3 | GO:0031594 | neuromuscular junction(GO:0031594) |
0.0 | 0.2 | GO:0043073 | germ cell nucleus(GO:0043073) |
0.0 | 0.9 | GO:0016605 | PML body(GO:0016605) |
0.0 | 0.1 | GO:0005858 | axonemal dynein complex(GO:0005858) axoneme part(GO:0044447) |
0.0 | 0.3 | GO:0005839 | proteasome core complex(GO:0005839) |
0.0 | 0.5 | GO:0031253 | cell projection membrane(GO:0031253) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 5.1 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
0.9 | 8.5 | GO:0004873 | asialoglycoprotein receptor activity(GO:0004873) |
0.7 | 2.8 | GO:0005026 | transforming growth factor beta receptor activity, type II(GO:0005026) |
0.7 | 2.7 | GO:0047006 | 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) |
0.6 | 2.9 | GO:0003680 | AT DNA binding(GO:0003680) |
0.5 | 1.6 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
0.5 | 1.6 | GO:0004392 | heme oxygenase (decyclizing) activity(GO:0004392) |
0.5 | 1.4 | GO:0047150 | betaine-homocysteine S-methyltransferase activity(GO:0047150) |
0.5 | 6.3 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
0.4 | 1.3 | GO:0015439 | heme-transporting ATPase activity(GO:0015439) |
0.4 | 1.6 | GO:0034190 | apolipoprotein receptor binding(GO:0034190) high-density lipoprotein particle receptor binding(GO:0070653) |
0.4 | 2.5 | GO:0030492 | hemoglobin binding(GO:0030492) |
0.3 | 0.9 | GO:0004948 | calcitonin receptor activity(GO:0004948) |
0.3 | 2.8 | GO:0019826 | oxygen sensor activity(GO:0019826) |
0.3 | 2.7 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
0.3 | 3.7 | GO:0070628 | proteasome binding(GO:0070628) |
0.2 | 0.7 | GO:0004607 | phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607) |
0.2 | 2.0 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
0.2 | 0.7 | GO:0019981 | interleukin-6 receptor activity(GO:0004915) oncostatin-M receptor activity(GO:0004924) ciliary neurotrophic factor receptor binding(GO:0005127) interleukin-6 binding(GO:0019981) interleukin-17 receptor activity(GO:0030368) |
0.2 | 0.8 | GO:0004657 | proline dehydrogenase activity(GO:0004657) |
0.2 | 1.6 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
0.2 | 1.0 | GO:0004064 | arylesterase activity(GO:0004064) |
0.2 | 1.9 | GO:0015643 | toxic substance binding(GO:0015643) |
0.2 | 0.8 | GO:0004909 | interleukin-1, Type I, activating receptor activity(GO:0004909) |
0.2 | 1.8 | GO:0070696 | transmembrane receptor protein serine/threonine kinase binding(GO:0070696) |
0.2 | 0.5 | GO:0016524 | latrotoxin receptor activity(GO:0016524) |
0.2 | 0.5 | GO:0050692 | DBD domain binding(GO:0050692) |
0.2 | 0.7 | GO:0042910 | xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910) |
0.2 | 1.0 | GO:0097493 | extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493) |
0.2 | 4.6 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
0.2 | 1.3 | GO:0004047 | aminomethyltransferase activity(GO:0004047) |
0.1 | 6.1 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
0.1 | 0.6 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
0.1 | 0.1 | GO:0043533 | inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533) |
0.1 | 0.4 | GO:0032089 | NACHT domain binding(GO:0032089) |
0.1 | 0.5 | GO:0008112 | nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760) |
0.1 | 2.0 | GO:0051787 | misfolded protein binding(GO:0051787) |
0.1 | 0.7 | GO:0048495 | Roundabout binding(GO:0048495) |
0.1 | 0.5 | GO:0043394 | proteoglycan binding(GO:0043394) |
0.1 | 3.1 | GO:0019003 | GDP binding(GO:0019003) |
0.1 | 1.6 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
0.1 | 0.4 | GO:0032145 | 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298) |
0.1 | 0.6 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
0.1 | 0.3 | GO:0030156 | benzodiazepine receptor binding(GO:0030156) |
0.1 | 1.9 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
0.1 | 0.5 | GO:0042156 | obsolete zinc-mediated transcriptional activator activity(GO:0042156) |
0.1 | 0.4 | GO:0046703 | beta-2-microglobulin binding(GO:0030881) natural killer cell lectin-like receptor binding(GO:0046703) |
0.1 | 1.2 | GO:0030346 | protein phosphatase 2B binding(GO:0030346) |
0.1 | 0.7 | GO:0016805 | dipeptidase activity(GO:0016805) |
0.1 | 0.4 | GO:0080030 | methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032) |
0.1 | 0.4 | GO:0004090 | carbonyl reductase (NADPH) activity(GO:0004090) |
0.1 | 1.9 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.1 | 0.4 | GO:0015086 | cadmium ion transmembrane transporter activity(GO:0015086) |
0.1 | 0.4 | GO:0043184 | vascular endothelial growth factor receptor 2 binding(GO:0043184) |
0.1 | 0.7 | GO:0008242 | omega peptidase activity(GO:0008242) |
0.1 | 0.2 | GO:0003996 | acyl-CoA ligase activity(GO:0003996) |
0.1 | 0.7 | GO:0004415 | hyalurononglucosaminidase activity(GO:0004415) |
0.1 | 0.2 | GO:0050528 | acyloxyacyl hydrolase activity(GO:0050528) |
0.1 | 0.2 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
0.1 | 0.9 | GO:0017127 | cholesterol transporter activity(GO:0017127) |
0.1 | 1.7 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
0.1 | 0.3 | GO:0000247 | C-8 sterol isomerase activity(GO:0000247) |
0.1 | 0.2 | GO:0004937 | alpha1-adrenergic receptor activity(GO:0004937) |
0.1 | 0.3 | GO:0034711 | inhibin binding(GO:0034711) |
0.1 | 0.4 | GO:0004046 | aminoacylase activity(GO:0004046) |
0.1 | 0.6 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
0.1 | 0.1 | GO:0016508 | long-chain-enoyl-CoA hydratase activity(GO:0016508) |
0.1 | 0.8 | GO:0004062 | aryl sulfotransferase activity(GO:0004062) |
0.1 | 1.2 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.1 | 5.8 | GO:0005254 | chloride channel activity(GO:0005254) |
0.1 | 0.8 | GO:0003706 | obsolete ligand-regulated transcription factor activity(GO:0003706) |
0.1 | 1.2 | GO:0008430 | selenium binding(GO:0008430) |
0.1 | 1.3 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
0.1 | 0.5 | GO:0017049 | GTP-Rho binding(GO:0017049) |
0.1 | 0.5 | GO:0003704 | obsolete specific RNA polymerase II transcription factor activity(GO:0003704) |
0.1 | 2.4 | GO:0004180 | carboxypeptidase activity(GO:0004180) |
0.1 | 0.3 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
0.0 | 0.6 | GO:0050998 | nitric-oxide synthase binding(GO:0050998) |
0.0 | 3.1 | GO:0005319 | lipid transporter activity(GO:0005319) |
0.0 | 0.7 | GO:0004017 | adenylate kinase activity(GO:0004017) |
0.0 | 0.6 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
0.0 | 0.6 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
0.0 | 0.7 | GO:0004467 | long-chain fatty acid-CoA ligase activity(GO:0004467) fatty acid ligase activity(GO:0015645) |
0.0 | 0.4 | GO:0030371 | translation repressor activity(GO:0030371) |
0.0 | 2.0 | GO:0002020 | protease binding(GO:0002020) |
0.0 | 0.1 | GO:0005459 | UDP-galactose transmembrane transporter activity(GO:0005459) |
0.0 | 0.2 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
0.0 | 0.8 | GO:0008484 | sulfuric ester hydrolase activity(GO:0008484) |
0.0 | 3.7 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.0 | 0.1 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
0.0 | 0.1 | GO:0047499 | calcium-independent phospholipase A2 activity(GO:0047499) |
0.0 | 0.1 | GO:0004897 | ciliary neurotrophic factor receptor activity(GO:0004897) |
0.0 | 0.1 | GO:0048184 | obsolete follistatin binding(GO:0048184) |
0.0 | 5.7 | GO:0004386 | helicase activity(GO:0004386) |
0.0 | 0.2 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
0.0 | 0.1 | GO:0044325 | ion channel binding(GO:0044325) |
0.0 | 1.4 | GO:0005518 | collagen binding(GO:0005518) |
0.0 | 0.3 | GO:0016944 | obsolete RNA polymerase II transcription elongation factor activity(GO:0016944) |
0.0 | 0.1 | GO:0047237 | glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237) |
0.0 | 0.1 | GO:0055103 | ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106) |
0.0 | 0.1 | GO:0004024 | alcohol dehydrogenase activity, zinc-dependent(GO:0004024) |
0.0 | 0.5 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
0.0 | 0.4 | GO:0003840 | gamma-glutamyltransferase activity(GO:0003840) |
0.0 | 0.1 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
0.0 | 0.3 | GO:0044548 | S100 protein binding(GO:0044548) |
0.0 | 0.1 | GO:0034187 | obsolete apolipoprotein E binding(GO:0034187) |
0.0 | 0.1 | GO:0042903 | tubulin deacetylase activity(GO:0042903) |
0.0 | 1.5 | GO:0042562 | hormone binding(GO:0042562) |
0.0 | 0.3 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.0 | 1.4 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
0.0 | 0.1 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
0.0 | 4.4 | GO:0003714 | transcription corepressor activity(GO:0003714) |
0.0 | 0.1 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
0.0 | 0.2 | GO:0004969 | histamine receptor activity(GO:0004969) |
0.0 | 0.1 | GO:0016167 | glial cell-derived neurotrophic factor receptor activity(GO:0016167) |
0.0 | 0.6 | GO:0008408 | 3'-5' exonuclease activity(GO:0008408) |
0.0 | 1.0 | GO:0005158 | insulin receptor binding(GO:0005158) |
0.0 | 0.2 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
0.0 | 0.1 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
0.0 | 0.5 | GO:0008307 | structural constituent of muscle(GO:0008307) |
0.0 | 0.2 | GO:0070325 | lipoprotein particle receptor binding(GO:0070325) |
0.0 | 0.2 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
0.0 | 0.2 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
0.0 | 1.4 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.0 | 0.1 | GO:0045294 | alpha-catenin binding(GO:0045294) |
0.0 | 0.4 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.0 | 0.1 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.0 | 0.3 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
0.0 | 0.1 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
0.0 | 0.1 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
0.0 | 0.2 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
0.0 | 0.1 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
0.0 | 0.2 | GO:0004407 | histone deacetylase activity(GO:0004407) |
0.0 | 0.1 | GO:0008158 | hedgehog receptor activity(GO:0008158) |
0.0 | 0.1 | GO:0005110 | frizzled-2 binding(GO:0005110) |
0.0 | 0.0 | GO:0019763 | immunoglobulin receptor activity(GO:0019763) |
0.0 | 0.2 | GO:0005522 | profilin binding(GO:0005522) |
0.0 | 0.1 | GO:0048406 | nerve growth factor binding(GO:0048406) |
0.0 | 0.1 | GO:0004982 | N-formyl peptide receptor activity(GO:0004982) |
0.0 | 0.2 | GO:0016780 | phosphotransferase activity, for other substituted phosphate groups(GO:0016780) |
0.0 | 0.2 | GO:0016273 | arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274) |
0.0 | 0.4 | GO:0050699 | WW domain binding(GO:0050699) |
0.0 | 0.1 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
0.0 | 2.1 | GO:0008083 | growth factor activity(GO:0008083) |
0.0 | 0.1 | GO:0051378 | serotonin binding(GO:0051378) |
0.0 | 0.1 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
0.0 | 0.1 | GO:0015355 | secondary active monocarboxylate transmembrane transporter activity(GO:0015355) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.5 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
0.0 | 0.7 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
0.0 | 0.9 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
0.0 | 2.5 | ST_INTEGRIN_SIGNALING_PATHWAY | Integrin Signaling Pathway |
0.0 | 0.4 | ST_G_ALPHA_I_PATHWAY | G alpha i Pathway |