Motif ID: ESRRB_ESRRG
Z-value: 2.145
Transcription factors associated with ESRRB_ESRRG:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
ESRRB | ENSG00000119715.10 | ESRRB |
ESRRG | ENSG00000196482.12 | ESRRG |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 4.7 | GO:0046108 | uridine metabolic process(GO:0046108) |
1.1 | 3.2 | GO:0071603 | negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) endothelial cell-cell adhesion(GO:0071603) |
0.8 | 5.7 | GO:0060414 | aorta development(GO:0035904) aorta morphogenesis(GO:0035909) aorta smooth muscle tissue morphogenesis(GO:0060414) |
0.8 | 4.6 | GO:0010561 | negative regulation of glycoprotein biosynthetic process(GO:0010561) |
0.7 | 2.8 | GO:0032849 | positive regulation of cellular pH reduction(GO:0032849) |
0.7 | 2.6 | GO:0045110 | intermediate filament bundle assembly(GO:0045110) |
0.6 | 2.4 | GO:0006089 | lactate metabolic process(GO:0006089) |
0.6 | 6.4 | GO:0006600 | creatine metabolic process(GO:0006600) |
0.5 | 1.4 | GO:0043006 | activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006) |
0.4 | 3.4 | GO:0045542 | positive regulation of cholesterol biosynthetic process(GO:0045542) |
0.4 | 2.1 | GO:0015827 | tryptophan transport(GO:0015827) leucine import(GO:0060356) |
0.4 | 5.6 | GO:0032456 | endocytic recycling(GO:0032456) |
0.2 | 2.5 | GO:0010799 | regulation of peptidyl-threonine phosphorylation(GO:0010799) positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
0.2 | 0.7 | GO:0046604 | regulation of mitotic centrosome separation(GO:0046602) positive regulation of mitotic centrosome separation(GO:0046604) |
0.2 | 0.9 | GO:0060649 | nipple development(GO:0060618) mammary gland bud elongation(GO:0060649) nipple morphogenesis(GO:0060658) nipple sheath formation(GO:0060659) |
0.2 | 1.1 | GO:0050703 | interleukin-1 alpha secretion(GO:0050703) |
0.2 | 1.0 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
0.2 | 0.5 | GO:0010248 | establishment or maintenance of transmembrane electrochemical gradient(GO:0010248) post-embryonic camera-type eye development(GO:0031077) |
0.2 | 0.5 | GO:0008050 | female courtship behavior(GO:0008050) |
0.2 | 1.0 | GO:0021520 | spinal cord motor neuron cell fate specification(GO:0021520) |
0.2 | 0.7 | GO:0030035 | microspike assembly(GO:0030035) |
0.2 | 0.8 | GO:0007144 | female meiosis I(GO:0007144) |
0.2 | 0.5 | GO:0006543 | glutamine catabolic process(GO:0006543) |
0.1 | 2.0 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
0.1 | 2.0 | GO:0018214 | peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214) |
0.1 | 0.4 | GO:0046521 | sphingoid catabolic process(GO:0046521) |
0.1 | 0.7 | GO:0090136 | epithelial cell-cell adhesion(GO:0090136) |
0.1 | 0.2 | GO:0032899 | regulation of neurotrophin production(GO:0032899) negative regulation of neurotrophin production(GO:0032900) |
0.1 | 0.4 | GO:0007506 | gonadal mesoderm development(GO:0007506) |
0.1 | 0.7 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) receptor catabolic process(GO:0032801) |
0.1 | 0.8 | GO:0042693 | muscle cell fate commitment(GO:0042693) |
0.1 | 2.1 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
0.1 | 1.0 | GO:0010224 | response to UV-B(GO:0010224) |
0.1 | 0.4 | GO:0090281 | negative regulation of calcium ion import(GO:0090281) |
0.1 | 0.3 | GO:0002158 | osteoclast proliferation(GO:0002158) |
0.1 | 1.7 | GO:0035329 | hippo signaling(GO:0035329) |
0.1 | 1.5 | GO:0006700 | C21-steroid hormone biosynthetic process(GO:0006700) |
0.1 | 0.9 | GO:0006105 | succinate metabolic process(GO:0006105) |
0.1 | 2.4 | GO:0043462 | regulation of ATPase activity(GO:0043462) |
0.1 | 0.5 | GO:0010820 | T cell chemotaxis(GO:0010818) regulation of T cell chemotaxis(GO:0010819) positive regulation of T cell chemotaxis(GO:0010820) regulation of lymphocyte chemotaxis(GO:1901623) regulation of lymphocyte migration(GO:2000401) positive regulation of lymphocyte migration(GO:2000403) regulation of T cell migration(GO:2000404) positive regulation of T cell migration(GO:2000406) |
0.1 | 0.5 | GO:0046349 | UDP-N-acetylglucosamine biosynthetic process(GO:0006048) amino sugar biosynthetic process(GO:0046349) |
0.1 | 0.1 | GO:0030812 | negative regulation of nucleotide catabolic process(GO:0030812) |
0.1 | 2.1 | GO:0015949 | nucleobase-containing small molecule interconversion(GO:0015949) |
0.1 | 0.4 | GO:0015824 | proline transport(GO:0015824) |
0.1 | 0.6 | GO:0060666 | dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666) |
0.1 | 0.2 | GO:0008212 | mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212) |
0.1 | 1.4 | GO:0015701 | bicarbonate transport(GO:0015701) |
0.1 | 0.5 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
0.1 | 0.1 | GO:0051563 | smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) |
0.1 | 0.6 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
0.1 | 0.6 | GO:0001706 | endoderm formation(GO:0001706) |
0.1 | 0.2 | GO:0008065 | establishment of blood-nerve barrier(GO:0008065) |
0.1 | 0.2 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
0.0 | 1.0 | GO:0042749 | regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187) |
0.0 | 1.2 | GO:0006378 | mRNA polyadenylation(GO:0006378) |
0.0 | 0.4 | GO:0000266 | mitochondrial fission(GO:0000266) |
0.0 | 0.2 | GO:0010766 | negative regulation of sodium ion transport(GO:0010766) |
0.0 | 0.6 | GO:0006688 | glycosphingolipid biosynthetic process(GO:0006688) |
0.0 | 0.3 | GO:0006937 | regulation of muscle contraction(GO:0006937) regulation of muscle system process(GO:0090257) |
0.0 | 0.9 | GO:0042325 | regulation of phosphorylation(GO:0042325) |
0.0 | 0.3 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
0.0 | 0.1 | GO:0046621 | negative regulation of organ growth(GO:0046621) |
0.0 | 0.3 | GO:0007616 | long-term memory(GO:0007616) |
0.0 | 0.1 | GO:0048670 | regulation of collateral sprouting(GO:0048670) |
0.0 | 0.1 | GO:0048537 | mucosal-associated lymphoid tissue development(GO:0048537) |
0.0 | 0.1 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
0.0 | 2.7 | GO:0030521 | androgen receptor signaling pathway(GO:0030521) |
0.0 | 0.3 | GO:0007216 | G-protein coupled glutamate receptor signaling pathway(GO:0007216) |
0.0 | 0.7 | GO:0045103 | intermediate filament-based process(GO:0045103) |
0.0 | 0.2 | GO:0007256 | activation of JNKK activity(GO:0007256) |
0.0 | 0.6 | GO:0071479 | cellular response to ionizing radiation(GO:0071479) |
0.0 | 2.2 | GO:0009408 | response to heat(GO:0009408) |
0.0 | 0.6 | GO:0010226 | response to lithium ion(GO:0010226) |
0.0 | 0.4 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
0.0 | 0.5 | GO:0034199 | activation of protein kinase A activity(GO:0034199) |
0.0 | 0.1 | GO:0006651 | diacylglycerol biosynthetic process(GO:0006651) |
0.0 | 0.6 | GO:0006942 | regulation of striated muscle contraction(GO:0006942) |
0.0 | 0.2 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.0 | 1.1 | GO:0007193 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193) |
0.0 | 0.5 | GO:0006278 | RNA-dependent DNA biosynthetic process(GO:0006278) |
0.0 | 0.1 | GO:0042417 | dopamine metabolic process(GO:0042417) |
0.0 | 0.3 | GO:0007080 | mitotic metaphase plate congression(GO:0007080) |
0.0 | 0.1 | GO:0018874 | benzoate metabolic process(GO:0018874) |
0.0 | 0.6 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
0.0 | 0.1 | GO:0044240 | multicellular organism lipid catabolic process(GO:0044240) |
0.0 | 0.1 | GO:0044413 | evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834) |
0.0 | 0.2 | GO:0006030 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
0.0 | 0.2 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
0.0 | 0.1 | GO:0016198 | axon choice point recognition(GO:0016198) |
0.0 | 1.1 | GO:0051084 | 'de novo' posttranslational protein folding(GO:0051084) |
0.0 | 0.7 | GO:0045445 | myoblast differentiation(GO:0045445) |
0.0 | 0.3 | GO:0045668 | negative regulation of osteoblast differentiation(GO:0045668) |
0.0 | 2.1 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
0.0 | 0.4 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
0.0 | 0.1 | GO:0051665 | membrane raft localization(GO:0051665) |
0.0 | 0.2 | GO:0048873 | homeostasis of number of cells within a tissue(GO:0048873) |
0.0 | 0.4 | GO:0032200 | telomere maintenance(GO:0000723) telomere organization(GO:0032200) |
0.0 | 0.2 | GO:0032784 | regulation of DNA-templated transcription, elongation(GO:0032784) |
0.0 | 0.2 | GO:0006743 | ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) |
0.0 | 0.2 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
0.0 | 0.6 | GO:0030049 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
0.0 | 0.1 | GO:0030146 | obsolete diuresis(GO:0030146) |
0.0 | 0.1 | GO:0060346 | bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430) |
0.0 | 0.2 | GO:0010332 | response to gamma radiation(GO:0010332) |
0.0 | 0.1 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
0.0 | 0.2 | GO:0048534 | hemopoiesis(GO:0030097) hematopoietic or lymphoid organ development(GO:0048534) |
0.0 | 0.8 | GO:0007588 | excretion(GO:0007588) |
0.0 | 0.1 | GO:1902622 | regulation of neutrophil chemotaxis(GO:0090022) regulation of neutrophil migration(GO:1902622) |
0.0 | 0.1 | GO:0006102 | isocitrate metabolic process(GO:0006102) |
0.0 | 0.4 | GO:0006903 | vesicle targeting(GO:0006903) |
0.0 | 0.1 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) negative regulation of phosphoprotein phosphatase activity(GO:0032515) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 3.0 | GO:0071664 | catenin-TCF7L2 complex(GO:0071664) |
0.3 | 3.2 | GO:0031430 | M band(GO:0031430) |
0.2 | 1.4 | GO:0070435 | Shc-EGFR complex(GO:0070435) |
0.2 | 2.5 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
0.2 | 1.5 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
0.2 | 3.0 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
0.1 | 1.0 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
0.1 | 1.7 | GO:0098647 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
0.1 | 6.2 | GO:0030175 | filopodium(GO:0030175) |
0.1 | 0.7 | GO:0005916 | fascia adherens(GO:0005916) |
0.1 | 2.1 | GO:0045263 | proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263) |
0.1 | 3.6 | GO:0045095 | keratin filament(GO:0045095) |
0.1 | 1.0 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
0.1 | 2.7 | GO:0005902 | microvillus(GO:0005902) |
0.1 | 0.5 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
0.1 | 3.3 | GO:0031594 | neuromuscular junction(GO:0031594) |
0.1 | 0.9 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
0.1 | 5.7 | GO:0016459 | myosin complex(GO:0016459) |
0.1 | 0.4 | GO:0005954 | calcium- and calmodulin-dependent protein kinase complex(GO:0005954) |
0.1 | 0.5 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
0.1 | 1.7 | GO:0005796 | Golgi lumen(GO:0005796) |
0.1 | 0.5 | GO:0000145 | exocyst(GO:0000145) |
0.0 | 0.4 | GO:0000275 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) |
0.0 | 0.2 | GO:0098984 | asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984) |
0.0 | 1.0 | GO:0005861 | troponin complex(GO:0005861) |
0.0 | 0.2 | GO:0030868 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
0.0 | 1.0 | GO:0001533 | cornified envelope(GO:0001533) |
0.0 | 0.3 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) histone pre-mRNA 3'end processing complex(GO:0071204) |
0.0 | 0.4 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
0.0 | 0.2 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
0.0 | 0.6 | GO:0046930 | pore complex(GO:0046930) |
0.0 | 3.3 | GO:0030016 | myofibril(GO:0030016) |
0.0 | 0.1 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
0.0 | 3.6 | GO:0005765 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
0.0 | 0.9 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
0.0 | 0.5 | GO:0097223 | acrosomal vesicle(GO:0001669) sperm part(GO:0097223) |
0.0 | 0.3 | GO:0030315 | T-tubule(GO:0030315) |
0.0 | 0.1 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
0.0 | 1.1 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.0 | 0.1 | GO:0032590 | dendrite membrane(GO:0032590) |
0.0 | 0.2 | GO:0045239 | tricarboxylic acid cycle enzyme complex(GO:0045239) |
0.0 | 0.1 | GO:0042382 | paraspeckles(GO:0042382) |
0.0 | 0.1 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
0.0 | 0.2 | GO:0033177 | proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177) |
0.0 | 0.3 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.0 | 0.3 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
0.0 | 0.7 | GO:0005882 | intermediate filament(GO:0005882) |
0.0 | 0.6 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
0.0 | 0.1 | GO:0098858 | actin-based cell projection(GO:0098858) |
0.0 | 1.1 | GO:0030496 | midbody(GO:0030496) |
0.0 | 0.3 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.0 | 0.1 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.0 | 1.5 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
0.0 | 0.2 | GO:0005732 | small nucleolar ribonucleoprotein complex(GO:0005732) |
0.0 | 2.8 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 6.4 | GO:0004111 | creatine kinase activity(GO:0004111) |
1.3 | 3.8 | GO:0008431 | vitamin E binding(GO:0008431) |
1.2 | 4.7 | GO:0004850 | uridine phosphorylase activity(GO:0004850) |
1.1 | 5.7 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
0.8 | 4.0 | GO:0034597 | phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) |
0.4 | 3.9 | GO:0045294 | alpha-catenin binding(GO:0045294) |
0.4 | 3.6 | GO:0033130 | acetylcholine receptor binding(GO:0033130) |
0.3 | 2.3 | GO:0004457 | lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459) |
0.3 | 4.6 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
0.3 | 5.6 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
0.3 | 0.8 | GO:0033867 | Fas-activated serine/threonine kinase activity(GO:0033867) |
0.3 | 2.5 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
0.2 | 1.0 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
0.2 | 0.7 | GO:0010861 | thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375) |
0.2 | 2.0 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
0.2 | 0.7 | GO:0016635 | oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635) |
0.2 | 2.8 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
0.2 | 0.5 | GO:0042285 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
0.2 | 1.0 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
0.2 | 1.1 | GO:0004340 | glucokinase activity(GO:0004340) |
0.2 | 1.4 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
0.1 | 2.2 | GO:0004017 | adenylate kinase activity(GO:0004017) |
0.1 | 0.8 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
0.1 | 2.0 | GO:0030546 | receptor activator activity(GO:0030546) |
0.1 | 0.5 | GO:0070324 | thyroid hormone binding(GO:0070324) |
0.1 | 0.4 | GO:0015193 | L-proline transmembrane transporter activity(GO:0015193) |
0.1 | 0.5 | GO:0004359 | glutaminase activity(GO:0004359) |
0.1 | 0.8 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
0.1 | 0.4 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
0.1 | 1.5 | GO:0050786 | RAGE receptor binding(GO:0050786) |
0.1 | 0.4 | GO:0004723 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) |
0.1 | 0.7 | GO:0030172 | troponin C binding(GO:0030172) |
0.1 | 0.2 | GO:0004769 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) steroid delta-isomerase activity(GO:0004769) |
0.1 | 0.2 | GO:0032795 | heterotrimeric G-protein binding(GO:0032795) |
0.1 | 0.2 | GO:0004461 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) lactose synthase activity(GO:0004461) |
0.1 | 0.2 | GO:0031877 | somatostatin receptor binding(GO:0031877) |
0.1 | 0.4 | GO:0017050 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
0.1 | 2.0 | GO:0004364 | glutathione transferase activity(GO:0004364) |
0.1 | 1.7 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.1 | 0.2 | GO:0000156 | phosphorelay response regulator activity(GO:0000156) |
0.1 | 0.3 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
0.1 | 0.5 | GO:0046790 | virion binding(GO:0046790) |
0.1 | 0.3 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
0.1 | 0.6 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
0.1 | 0.5 | GO:0015288 | porin activity(GO:0015288) |
0.1 | 0.5 | GO:0051400 | BH domain binding(GO:0051400) |
0.1 | 0.5 | GO:0070569 | uridylyltransferase activity(GO:0070569) |
0.1 | 0.4 | GO:0008432 | JUN kinase binding(GO:0008432) |
0.0 | 0.3 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
0.0 | 1.4 | GO:0005452 | inorganic anion exchanger activity(GO:0005452) |
0.0 | 0.4 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
0.0 | 2.8 | GO:0050681 | androgen receptor binding(GO:0050681) |
0.0 | 0.7 | GO:0070411 | I-SMAD binding(GO:0070411) |
0.0 | 3.8 | GO:0008307 | structural constituent of muscle(GO:0008307) |
0.0 | 0.7 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
0.0 | 0.7 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
0.0 | 0.6 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.0 | 0.2 | GO:0019166 | trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166) |
0.0 | 1.0 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
0.0 | 2.5 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
0.0 | 0.3 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
0.0 | 2.9 | GO:0008094 | DNA-dependent ATPase activity(GO:0008094) |
0.0 | 0.2 | GO:0004775 | succinate-CoA ligase (ADP-forming) activity(GO:0004775) |
0.0 | 1.1 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
0.0 | 0.3 | GO:0016018 | cyclosporin A binding(GO:0016018) |
0.0 | 0.2 | GO:0019871 | sodium channel inhibitor activity(GO:0019871) |
0.0 | 0.1 | GO:0031755 | endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755) |
0.0 | 0.7 | GO:0008430 | selenium binding(GO:0008430) |
0.0 | 2.6 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.0 | 0.4 | GO:0042162 | telomeric DNA binding(GO:0042162) |
0.0 | 1.2 | GO:0005080 | protein kinase C binding(GO:0005080) |
0.0 | 0.3 | GO:0047617 | acyl-CoA hydrolase activity(GO:0047617) |
0.0 | 0.9 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
0.0 | 0.1 | GO:0004771 | sterol esterase activity(GO:0004771) |
0.0 | 0.3 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
0.0 | 0.1 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390) |
0.0 | 0.3 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
0.0 | 0.2 | GO:0003847 | 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847) |
0.0 | 0.1 | GO:0004449 | isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
0.0 | 0.1 | GO:0003996 | acyl-CoA ligase activity(GO:0003996) |
0.0 | 0.1 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) |
0.0 | 0.1 | GO:0016681 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
0.0 | 0.1 | GO:0034594 | phosphatidylinositol trisphosphate phosphatase activity(GO:0034594) |
0.0 | 0.1 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
0.0 | 0.2 | GO:0004568 | chitinase activity(GO:0004568) |
0.0 | 0.2 | GO:0003711 | obsolete transcription elongation regulator activity(GO:0003711) |
0.0 | 0.2 | GO:0017070 | U6 snRNA binding(GO:0017070) |
0.0 | 0.3 | GO:0030332 | cyclin binding(GO:0030332) |
0.0 | 0.2 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
0.0 | 0.3 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
0.0 | 1.7 | GO:0047485 | protein N-terminus binding(GO:0047485) |
0.0 | 3.1 | GO:0008168 | methyltransferase activity(GO:0008168) |
0.0 | 0.5 | GO:0004385 | guanylate kinase activity(GO:0004385) |
0.0 | 0.0 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970) |
0.0 | 0.2 | GO:0016888 | endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888) |
0.0 | 0.3 | GO:0005003 | ephrin receptor activity(GO:0005003) |
0.0 | 0.7 | GO:0004871 | signal transducer activity(GO:0004871) |
0.0 | 0.4 | GO:0070888 | E-box binding(GO:0070888) |
0.0 | 0.1 | GO:0008160 | protein tyrosine phosphatase activator activity(GO:0008160) protein phosphatase activator activity(GO:0072542) |
0.0 | 0.6 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
0.0 | 2.3 | GO:0005516 | calmodulin binding(GO:0005516) |
0.0 | 0.1 | GO:0043531 | ADP binding(GO:0043531) |
0.0 | 0.1 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
0.0 | 0.2 | GO:0030553 | cGMP binding(GO:0030553) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 5.6 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
0.1 | 0.8 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
0.0 | 2.2 | ST_ADRENERGIC | Adrenergic Pathway |
0.0 | 0.5 | SA_PROGRAMMED_CELL_DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
0.0 | 0.6 | SA_G1_AND_S_PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |