Motif ID: ETV6
Z-value: 1.301
Transcription factors associated with ETV6:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| ETV6 | ENSG00000139083.6 | ETV6 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 1.5 | GO:0000354 | cis assembly of pre-catalytic spliceosome(GO:0000354) |
| 0.4 | 1.5 | GO:0034442 | plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161) |
| 0.3 | 1.3 | GO:0045048 | protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816) |
| 0.2 | 0.8 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
| 0.2 | 0.5 | GO:0006167 | AMP biosynthetic process(GO:0006167) |
| 0.1 | 0.4 | GO:0046833 | positive regulation of RNA export from nucleus(GO:0046833) |
| 0.1 | 0.6 | GO:0045091 | regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091) |
| 0.1 | 1.3 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.1 | 1.4 | GO:0051918 | negative regulation of fibrinolysis(GO:0051918) |
| 0.1 | 1.7 | GO:0000052 | citrulline metabolic process(GO:0000052) arginine catabolic process(GO:0006527) |
| 0.1 | 1.3 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 0.1 | 0.3 | GO:0034635 | glutathione transport(GO:0034635) tripeptide transport(GO:0042939) |
| 0.1 | 0.3 | GO:0048263 | determination of dorsal identity(GO:0048263) |
| 0.1 | 0.2 | GO:0031297 | replication fork processing(GO:0031297) |
| 0.1 | 0.2 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.1 | 0.2 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
| 0.1 | 0.3 | GO:0030259 | lipid glycosylation(GO:0030259) |
| 0.1 | 0.3 | GO:0051013 | microtubule severing(GO:0051013) |
| 0.1 | 0.7 | GO:0006465 | signal peptide processing(GO:0006465) |
| 0.1 | 0.5 | GO:0008089 | anterograde axonal transport(GO:0008089) |
| 0.1 | 0.2 | GO:0015920 | lipopolysaccharide transport(GO:0015920) |
| 0.1 | 0.1 | GO:0071504 | response to heparin(GO:0071503) cellular response to heparin(GO:0071504) |
| 0.1 | 0.2 | GO:0001757 | somite specification(GO:0001757) |
| 0.1 | 0.2 | GO:0035234 | ectopic germ cell programmed cell death(GO:0035234) |
| 0.0 | 0.4 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
| 0.0 | 0.3 | GO:0006422 | aspartyl-tRNA aminoacylation(GO:0006422) |
| 0.0 | 0.4 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
| 0.0 | 0.1 | GO:0072334 | UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481) nucleotide transmembrane transport(GO:1901679) |
| 0.0 | 0.2 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.0 | 0.2 | GO:0009103 | lipopolysaccharide biosynthetic process(GO:0009103) |
| 0.0 | 0.1 | GO:0043628 | ncRNA 3'-end processing(GO:0043628) |
| 0.0 | 0.8 | GO:0045730 | respiratory burst(GO:0045730) |
| 0.0 | 1.4 | GO:0030593 | neutrophil chemotaxis(GO:0030593) neutrophil migration(GO:1990266) |
| 0.0 | 0.3 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.0 | 0.3 | GO:0000281 | mitotic cytokinesis(GO:0000281) |
| 0.0 | 0.2 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.0 | 0.4 | GO:0007616 | long-term memory(GO:0007616) |
| 0.0 | 0.2 | GO:0032495 | response to muramyl dipeptide(GO:0032495) |
| 0.0 | 0.6 | GO:0075713 | establishment of viral latency(GO:0019043) establishment of integrated proviral latency(GO:0075713) |
| 0.0 | 0.1 | GO:0045896 | regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897) |
| 0.0 | 0.2 | GO:0035058 | nonmotile primary cilium assembly(GO:0035058) |
| 0.0 | 0.4 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.0 | 0.1 | GO:0042320 | positive regulation of synaptic transmission, dopaminergic(GO:0032226) regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) |
| 0.0 | 0.1 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 0.0 | 0.1 | GO:0006432 | phenylalanyl-tRNA aminoacylation(GO:0006432) |
| 0.0 | 0.2 | GO:0031122 | cytoplasmic microtubule organization(GO:0031122) |
| 0.0 | 0.2 | GO:0045650 | negative regulation of macrophage differentiation(GO:0045650) |
| 0.0 | 0.2 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
| 0.0 | 0.1 | GO:0042769 | DNA damage response, detection of DNA damage(GO:0042769) |
| 0.0 | 0.9 | GO:0046324 | regulation of glucose import(GO:0046324) |
| 0.0 | 0.3 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
| 0.0 | 0.3 | GO:0048207 | vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114) |
| 0.0 | 0.2 | GO:0046653 | tetrahydrofolate metabolic process(GO:0046653) |
| 0.0 | 1.2 | GO:0050434 | positive regulation of viral transcription(GO:0050434) |
| 0.0 | 1.0 | GO:0046320 | regulation of fatty acid oxidation(GO:0046320) |
| 0.0 | 0.3 | GO:0016558 | protein import into peroxisome matrix(GO:0016558) |
| 0.0 | 0.2 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.0 | 0.3 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
| 0.0 | 0.1 | GO:0031047 | gene silencing by RNA(GO:0031047) |
| 0.0 | 0.2 | GO:0032727 | positive regulation of interferon-alpha production(GO:0032727) |
| 0.0 | 0.5 | GO:0006024 | glycosaminoglycan biosynthetic process(GO:0006024) |
| 0.0 | 0.3 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 0.0 | 0.4 | GO:0006952 | defense response(GO:0006952) |
| 0.0 | 0.4 | GO:0006884 | cell volume homeostasis(GO:0006884) |
| 0.0 | 0.1 | GO:0032007 | negative regulation of TOR signaling(GO:0032007) |
| 0.0 | 0.2 | GO:0016601 | Rac protein signal transduction(GO:0016601) |
| 0.0 | 0.2 | GO:0030968 | endoplasmic reticulum unfolded protein response(GO:0030968) cellular response to unfolded protein(GO:0034620) cellular response to topologically incorrect protein(GO:0035967) |
| 0.0 | 0.2 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
| 0.0 | 0.4 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.3 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 0.2 | 0.4 | GO:0046540 | U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526) |
| 0.2 | 1.5 | GO:0005682 | U5 snRNP(GO:0005682) |
| 0.1 | 0.9 | GO:0000300 | obsolete peripheral to membrane of membrane fraction(GO:0000300) |
| 0.1 | 0.4 | GO:0005686 | U2 snRNP(GO:0005686) |
| 0.1 | 0.4 | GO:0005674 | transcription factor TFIIF complex(GO:0005674) |
| 0.1 | 1.7 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
| 0.1 | 0.9 | GO:0005638 | lamin filament(GO:0005638) |
| 0.1 | 1.5 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
| 0.1 | 0.9 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.1 | 0.2 | GO:0000800 | lateral element(GO:0000800) |
| 0.1 | 0.2 | GO:0071797 | LUBAC complex(GO:0071797) |
| 0.0 | 0.3 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 0.0 | 0.4 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
| 0.0 | 0.4 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.0 | 0.4 | GO:0034518 | mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518) |
| 0.0 | 0.2 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 0.0 | 0.3 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.0 | 0.3 | GO:0000145 | exocyst(GO:0000145) |
| 0.0 | 0.8 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 0.6 | GO:0000795 | synaptonemal complex(GO:0000795) |
| 0.0 | 0.1 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.0 | 1.3 | GO:0098636 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
| 0.0 | 0.2 | GO:0072487 | MSL complex(GO:0072487) |
| 0.0 | 0.1 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
| 0.0 | 0.2 | GO:0000445 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.0 | 0.4 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.0 | 0.4 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.0 | 0.2 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.0 | 0.4 | GO:0031231 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.0 | 0.1 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
| 0.0 | 0.5 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 0.2 | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) |
| 0.0 | 0.1 | GO:0071817 | MMXD complex(GO:0071817) |
| 0.0 | 0.8 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.0 | 0.3 | GO:0005763 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.0 | 0.2 | GO:0000808 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 0.0 | 0.1 | GO:0019815 | immunoglobulin complex(GO:0019814) B cell receptor complex(GO:0019815) |
| 0.0 | 0.1 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
| 0.0 | 1.5 | GO:0000151 | ubiquitin ligase complex(GO:0000151) |
| 0.0 | 0.4 | GO:0033177 | proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177) |
| 0.0 | 0.3 | GO:0030532 | small nuclear ribonucleoprotein complex(GO:0030532) |
| 0.0 | 0.2 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 0.5 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 1.4 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.7 | GO:0016403 | dimethylargininase activity(GO:0016403) |
| 0.3 | 1.3 | GO:0000827 | inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) |
| 0.2 | 0.6 | GO:0061505 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
| 0.2 | 0.5 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
| 0.2 | 0.5 | GO:0004914 | interleukin-5 receptor activity(GO:0004914) |
| 0.2 | 0.5 | GO:0003980 | UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980) |
| 0.1 | 0.4 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 0.1 | 0.5 | GO:0016842 | amidine-lyase activity(GO:0016842) |
| 0.1 | 0.4 | GO:0008148 | obsolete negative transcription elongation factor activity(GO:0008148) |
| 0.1 | 1.3 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.1 | 0.3 | GO:0031698 | beta-2 adrenergic receptor binding(GO:0031698) |
| 0.1 | 0.2 | GO:0003896 | DNA primase activity(GO:0003896) |
| 0.1 | 1.4 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.1 | 0.2 | GO:0043140 | bubble DNA binding(GO:0000405) obsolete DNA strand annealing activity(GO:0000739) ATP-dependent 3'-5' DNA helicase activity(GO:0043140) |
| 0.1 | 0.9 | GO:0005521 | lamin binding(GO:0005521) |
| 0.1 | 0.2 | GO:0016402 | pristanoyl-CoA oxidase activity(GO:0016402) |
| 0.1 | 0.2 | GO:0004677 | DNA-dependent protein kinase activity(GO:0004677) |
| 0.0 | 0.2 | GO:0004525 | ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) |
| 0.0 | 0.2 | GO:0008898 | S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898) |
| 0.0 | 0.4 | GO:0019211 | phosphatase activator activity(GO:0019211) |
| 0.0 | 0.3 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.0 | 0.3 | GO:0004815 | aspartate-tRNA ligase activity(GO:0004815) |
| 0.0 | 0.1 | GO:0005459 | UDP-galactose transmembrane transporter activity(GO:0005459) |
| 0.0 | 0.1 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
| 0.0 | 0.2 | GO:0003997 | acyl-CoA oxidase activity(GO:0003997) |
| 0.0 | 0.2 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
| 0.0 | 0.3 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 0.0 | 0.2 | GO:0003917 | DNA topoisomerase activity(GO:0003916) DNA topoisomerase type I activity(GO:0003917) |
| 0.0 | 0.4 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.0 | 0.3 | GO:0047429 | nucleoside-triphosphate diphosphatase activity(GO:0047429) |
| 0.0 | 0.1 | GO:0016534 | cyclin-dependent protein kinase 5 activator activity(GO:0016534) |
| 0.0 | 0.1 | GO:0042156 | obsolete zinc-mediated transcriptional activator activity(GO:0042156) |
| 0.0 | 0.2 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
| 0.0 | 0.2 | GO:0050700 | CARD domain binding(GO:0050700) |
| 0.0 | 0.1 | GO:0042808 | obsolete neuronal Cdc2-like kinase binding(GO:0042808) |
| 0.0 | 0.2 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.0 | 0.3 | GO:0017169 | CDP-alcohol phosphatidyltransferase activity(GO:0017169) |
| 0.0 | 0.1 | GO:0042609 | CD4 receptor binding(GO:0042609) |
| 0.0 | 0.4 | GO:0005522 | profilin binding(GO:0005522) |
| 0.0 | 1.4 | GO:0004221 | obsolete ubiquitin thiolesterase activity(GO:0004221) |
| 0.0 | 0.3 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.0 | 1.6 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.0 | 0.1 | GO:0035326 | enhancer binding(GO:0035326) |
| 0.0 | 0.2 | GO:0061659 | ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659) |
| 0.0 | 0.1 | GO:0034416 | bisphosphoglycerate phosphatase activity(GO:0034416) |
| 0.0 | 0.1 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
| 0.0 | 0.2 | GO:0003711 | obsolete transcription elongation regulator activity(GO:0003711) |
| 0.0 | 0.2 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.0 | 1.2 | GO:0001948 | glycoprotein binding(GO:0001948) |
| 0.0 | 0.3 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
| 0.0 | 1.5 | GO:0005319 | lipid transporter activity(GO:0005319) |
| 0.0 | 0.1 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.0 | 0.1 | GO:0003920 | GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657) |
| 0.0 | 0.1 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 0.0 | 1.6 | GO:0008026 | ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035) |
| 0.0 | 0.3 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.0 | 0.1 | GO:0015355 | secondary active monocarboxylate transmembrane transporter activity(GO:0015355) |
| 0.0 | 0.2 | GO:0070567 | cytidylyltransferase activity(GO:0070567) |
| 0.0 | 0.1 | GO:0004999 | vasoactive intestinal polypeptide receptor activity(GO:0004999) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.7 | SA_FAS_SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 0.0 | 0.4 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.0 | 0.9 | ST_B_CELL_ANTIGEN_RECEPTOR | B Cell Antigen Receptor |
