Motif ID: EVX2

Z-value: 0.847


Transcription factors associated with EVX2:

Gene SymbolEntrez IDGene Name
EVX2 ENSG00000174279.4 EVX2



Activity profile for motif EVX2.

activity profile for motif EVX2


Sorted Z-values histogram for motif EVX2

Sorted Z-values for motif EVX2



Network of associatons between targets according to the STRING database.



Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_55562479 1.954 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr15_-_55563072 1.874 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A


RAB27A, member RAS oncogene family


chr15_-_55562582 1.335 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr11_-_115375107 0.896 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1





cell adhesion molecule 1





chr4_-_41884620 0.694 ENST00000504870.1
LINC00682
long intergenic non-protein coding RNA 682
chr15_+_41057818 0.598 ENST00000558467.1
GCHFR
GTP cyclohydrolase I feedback regulator
chr3_+_111718173 0.492 ENST00000494932.1
TAGLN3
transgelin 3
chr12_+_28410128 0.464 ENST00000381259.1
ENST00000381256.1
CCDC91

coiled-coil domain containing 91

chr3_+_111718036 0.305 ENST00000455401.2
TAGLN3
transgelin 3
chr17_-_27418537 0.250 ENST00000408971.2
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr1_+_28261533 0.247 ENST00000411604.1
ENST00000373888.4
SMPDL3B

sphingomyelin phosphodiesterase, acid-like 3B

chr6_-_111927062 0.235 ENST00000359831.4
TRAF3IP2
TRAF3 interacting protein 2
chr3_+_111717600 0.234 ENST00000273368.4
TAGLN3
transgelin 3
chr3_+_111717511 0.199 ENST00000478951.1
ENST00000393917.2
TAGLN3

transgelin 3

chr17_-_40337470 0.195 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr17_-_9929581 0.188 ENST00000437099.2
ENST00000396115.2
GAS7

growth arrest-specific 7

chr18_-_33709268 0.110 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
SLC39A6


solute carrier family 39 (zinc transporter), member 6


chr1_+_28261492 0.103 ENST00000373894.3
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr1_+_28261621 0.094 ENST00000549094.1
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr1_+_160160346 0.078 ENST00000368078.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr3_+_115342349 0.068 ENST00000393780.3
GAP43
growth associated protein 43
chr1_-_151431647 0.058 ENST00000368863.2
ENST00000409503.1
ENST00000491586.1
ENST00000533351.1
ENST00000540984.1
POGZ




pogo transposable element with ZNF domain




chr1_+_160160283 0.057 ENST00000368079.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr6_-_62996066 0.007 ENST00000281156.4
KHDRBS2
KH domain containing, RNA binding, signal transduction associated 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 5.2 GO:0043316 natural killer cell activation involved in immune response(GO:0002323) cytotoxic T cell degranulation(GO:0043316) natural killer cell degranulation(GO:0043320)
0.2 0.9 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.2 0.6 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.1 0.2 GO:0051971 positive regulation of transmission of nerve impulse(GO:0051971)
0.0 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.2 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 1.1 GO:0008021 synaptic vesicle(GO:0008021)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.2 GO:0031489 myosin V binding(GO:0031489)
0.2 0.6 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.9 GO:0030165 PDZ domain binding(GO:0030165)