Motif ID: FOXA1

Z-value: 1.535


Transcription factors associated with FOXA1:

Gene SymbolEntrez IDGene Name
FOXA1 ENSG00000129514.4 FOXA1



Activity profile for motif FOXA1.

activity profile for motif FOXA1


Sorted Z-values histogram for motif FOXA1

Sorted Z-values for motif FOXA1



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXA1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_26695013 6.616 ENST00000555059.2
CTB-96E2.2
Homeobox protein SEBOX
chr17_-_26694979 6.526 ENST00000438614.1
VTN
vitronectin
chr2_-_21266935 4.851 ENST00000233242.1
APOB
apolipoprotein B
chr3_+_186330712 4.588 ENST00000411641.2
ENST00000273784.5
AHSG

alpha-2-HS-glycoprotein

chr17_+_79953310 4.285 ENST00000582355.2
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr14_-_94789663 3.989 ENST00000557225.1
ENST00000341584.3
SERPINA6

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6

chr3_-_148939835 3.943 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr22_+_21128167 3.873 ENST00000215727.5
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr4_-_70080449 2.870 ENST00000446444.1
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr4_-_155533787 2.738 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
FGG





fibrinogen gamma chain





chr17_-_39684550 2.204 ENST00000455635.1
ENST00000361566.3
KRT19

keratin 19

chr6_-_41715128 2.116 ENST00000356667.4
ENST00000373025.3
ENST00000425343.2
PGC


progastricsin (pepsinogen C)


chr17_+_72426891 1.905 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr8_+_126442563 1.877 ENST00000311922.3
TRIB1
tribbles pseudokinase 1
chr1_-_27240455 1.839 ENST00000254227.3
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr1_+_227127981 1.822 ENST00000366778.1
ENST00000366777.3
ENST00000458507.2
ADCK3


aarF domain containing kinase 3


chr19_+_18496957 1.783 ENST00000252809.3
GDF15
growth differentiation factor 15
chrX_-_20236970 1.581 ENST00000379548.4
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr14_-_38064198 1.575 ENST00000250448.2
FOXA1
forkhead box A1
chr17_+_72427477 1.508 ENST00000342648.5
ENST00000481232.1
GPRC5C

G protein-coupled receptor, family C, group 5, member C

chr14_-_21493884 1.274 ENST00000556974.1
ENST00000554419.1
ENST00000298687.5
ENST00000397858.1
ENST00000360463.3
ENST00000350792.3
ENST00000397847.2
NDRG2






NDRG family member 2






chr17_+_74372662 1.271 ENST00000591651.1
ENST00000545180.1
SPHK1

sphingosine kinase 1

chr12_-_48398104 1.259 ENST00000337299.6
ENST00000380518.3
COL2A1

collagen, type II, alpha 1

chr20_-_45984401 1.209 ENST00000311275.7
ZMYND8
zinc finger, MYND-type containing 8
chr18_+_60382672 1.174 ENST00000400316.4
ENST00000262719.5
PHLPP1

PH domain and leucine rich repeat protein phosphatase 1

chr1_+_214161854 1.158 ENST00000435016.1
PROX1
prospero homeobox 1
chr3_+_142315225 1.144 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
PLS1





plastin 1





chr3_-_129407535 1.134 ENST00000432054.2
TMCC1
transmembrane and coiled-coil domain family 1
chr16_-_87970122 1.083 ENST00000309893.2
CA5A
carbonic anhydrase VA, mitochondrial
chr13_-_46716969 1.069 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr12_-_71551868 1.061 ENST00000247829.3
TSPAN8
tetraspanin 8
chr2_+_58655461 1.031 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
AC007092.1


long intergenic non-protein coding RNA 1122


chr12_-_53343602 1.003 ENST00000546897.1
ENST00000552551.1
KRT8

keratin 8

chr1_-_57431679 0.899 ENST00000371237.4
ENST00000535057.1
ENST00000543257.1
C8B


complement component 8, beta polypeptide


chr6_+_10528560 0.876 ENST00000379597.3
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr7_+_134832808 0.853 ENST00000275767.3
TMEM140
transmembrane protein 140
chrX_+_9431324 0.852 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X





transducin (beta)-like 1X-linked





chr20_+_306177 0.838 ENST00000544632.1
SOX12
SRY (sex determining region Y)-box 12
chr12_+_121416489 0.835 ENST00000541395.1
ENST00000544413.1
HNF1A

HNF1 homeobox A

chr21_-_43735446 0.796 ENST00000398431.2
TFF3
trefoil factor 3 (intestinal)
chr12_-_71551652 0.733 ENST00000546561.1
TSPAN8
tetraspanin 8
chr7_+_73242490 0.707 ENST00000431918.1
CLDN4
claudin 4
chr5_+_156712372 0.698 ENST00000541131.1
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr10_-_73848086 0.691 ENST00000536168.1
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr14_-_21493649 0.677 ENST00000553442.1
ENST00000555869.1
ENST00000556457.1
ENST00000397844.2
ENST00000554415.1
NDRG2




NDRG family member 2




chr6_+_7107999 0.652 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
RREB1


ras responsive element binding protein 1


chr11_+_120973375 0.605 ENST00000264037.2
TECTA
tectorin alpha
chr20_+_306221 0.602 ENST00000342665.2
SOX12
SRY (sex determining region Y)-box 12
chr2_-_172017393 0.591 ENST00000442919.2
TLK1
tousled-like kinase 1
chr1_+_174933899 0.574 ENST00000367688.3
RABGAP1L
RAB GTPase activating protein 1-like
chr2_-_172290482 0.555 ENST00000442541.1
ENST00000392599.2
ENST00000375258.4
METTL8


methyltransferase like 8


chr17_-_19651668 0.546 ENST00000494157.2
ENST00000225740.6
ALDH3A1

aldehyde dehydrogenase 3 family, member A1

chr17_+_4613776 0.543 ENST00000269260.2
ARRB2
arrestin, beta 2
chr14_-_64971288 0.539 ENST00000394715.1
ZBTB25
zinc finger and BTB domain containing 25
chr6_+_135502501 0.509 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB






v-myb avian myeloblastosis viral oncogene homolog






chr2_-_172017343 0.505 ENST00000431350.2
ENST00000360843.3
TLK1

tousled-like kinase 1

chr2_-_165424973 0.493 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chr5_-_115872142 0.480 ENST00000510263.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr4_+_187187098 0.460 ENST00000403665.2
ENST00000264692.4
F11

coagulation factor XI

chr4_+_68424434 0.460 ENST00000265404.2
ENST00000396225.1
STAP1

signal transducing adaptor family member 1

chr18_-_52626622 0.451 ENST00000591504.1
CCDC68
coiled-coil domain containing 68
chr17_+_4613918 0.447 ENST00000574954.1
ENST00000346341.2
ENST00000572457.1
ENST00000381488.6
ENST00000412477.3
ENST00000571428.1
ENST00000575877.1
ARRB2






arrestin, beta 2






chr14_-_24911448 0.445 ENST00000555355.1
ENST00000553343.1
ENST00000556523.1
ENST00000556249.1
ENST00000538105.2
ENST00000555225.1
SDR39U1





short chain dehydrogenase/reductase family 39U, member 1





chr13_+_76334567 0.444 ENST00000321797.8
LMO7
LIM domain 7
chr19_-_15443318 0.424 ENST00000360016.5
BRD4
bromodomain containing 4
chr6_+_135502466 0.423 ENST00000367814.4
MYB
v-myb avian myeloblastosis viral oncogene homolog
chrX_+_37639302 0.416 ENST00000545017.1
ENST00000536160.1
CYBB

cytochrome b-245, beta polypeptide

chrX_+_37639264 0.411 ENST00000378588.4
CYBB
cytochrome b-245, beta polypeptide
chr6_+_135502408 0.401 ENST00000341911.5
ENST00000442647.2
ENST00000316528.8
MYB


v-myb avian myeloblastosis viral oncogene homolog


chr2_-_158345462 0.397 ENST00000439355.1
ENST00000540637.1
CYTIP

cytohesin 1 interacting protein

chr3_+_52811596 0.397 ENST00000542827.1
ENST00000273283.2
ITIH1

inter-alpha-trypsin inhibitor heavy chain 1

chr12_+_121416340 0.397 ENST00000257555.6
ENST00000400024.2
HNF1A

HNF1 homeobox A

chr7_+_116654935 0.396 ENST00000432298.1
ENST00000422922.1
ST7

suppression of tumorigenicity 7

chr20_+_52105495 0.378 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr8_-_71316021 0.373 ENST00000452400.2
NCOA2
nuclear receptor coactivator 2
chr6_+_106546808 0.363 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr13_+_76334795 0.357 ENST00000526202.1
ENST00000465261.2
LMO7

LIM domain 7

chr7_+_28452130 0.356 ENST00000357727.2
CREB5
cAMP responsive element binding protein 5
chr3_-_120068143 0.349 ENST00000295628.3
LRRC58
leucine rich repeat containing 58
chr4_+_170581213 0.339 ENST00000507875.1
CLCN3
chloride channel, voltage-sensitive 3
chrX_+_24167746 0.339 ENST00000428571.1
ENST00000539115.1
ZFX

zinc finger protein, X-linked

chrX_+_22050546 0.336 ENST00000379374.4
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr7_+_112063192 0.334 ENST00000005558.4
IFRD1
interferon-related developmental regulator 1
chr7_+_95115210 0.334 ENST00000428113.1
ENST00000325885.5
ASB4

ankyrin repeat and SOCS box containing 4

chr14_-_31926701 0.331 ENST00000310850.4
DTD2
D-tyrosyl-tRNA deacylase 2 (putative)
chr9_-_20622478 0.309 ENST00000355930.6
ENST00000380338.4
MLLT3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr6_+_31582961 0.306 ENST00000376059.3
ENST00000337917.7
AIF1

allograft inflammatory factor 1

chr1_+_12538594 0.295 ENST00000543710.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr18_-_25616519 0.290 ENST00000399380.3
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr6_+_33589161 0.285 ENST00000605930.1
ITPR3
inositol 1,4,5-trisphosphate receptor, type 3
chr19_-_48894104 0.282 ENST00000597017.1
KDELR1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr6_-_89927151 0.280 ENST00000454853.2
GABRR1
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr6_+_108977520 0.277 ENST00000540898.1
FOXO3
forkhead box O3
chrX_-_24665208 0.276 ENST00000356768.4
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr2_+_47630108 0.269 ENST00000233146.2
ENST00000454849.1
ENST00000543555.1
MSH2


mutS homolog 2


chr4_-_100356844 0.267 ENST00000437033.2
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr8_+_119294456 0.265 ENST00000366457.2
AC023590.1
Uncharacterized protein
chr3_+_148545586 0.253 ENST00000282957.4
ENST00000468341.1
CPB1

carboxypeptidase B1 (tissue)

chr9_-_98279241 0.253 ENST00000437951.1
ENST00000375274.2
ENST00000430669.2
ENST00000468211.2
PTCH1



patched 1



chr2_-_220042825 0.244 ENST00000409789.1
CNPPD1
cyclin Pas1/PHO80 domain containing 1
chr9_-_123239632 0.238 ENST00000416449.1
CDK5RAP2
CDK5 regulatory subunit associated protein 2
chr12_+_10658489 0.234 ENST00000538173.1
EIF2S3L
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr11_+_71249071 0.227 ENST00000398534.3
KRTAP5-8
keratin associated protein 5-8
chr2_-_214016314 0.224 ENST00000434687.1
ENST00000374319.4
IKZF2

IKAROS family zinc finger 2 (Helios)

chr6_+_112375462 0.224 ENST00000361714.1
WISP3
WNT1 inducible signaling pathway protein 3
chr2_+_47630255 0.215 ENST00000406134.1
MSH2
mutS homolog 2
chr1_-_216596738 0.208 ENST00000307340.3
ENST00000366943.2
ENST00000366942.3
USH2A


Usher syndrome 2A (autosomal recessive, mild)


chr14_+_37126765 0.206 ENST00000402703.2
PAX9
paired box 9
chr12_-_772901 0.206 ENST00000305108.4
NINJ2
ninjurin 2
chrX_+_135730373 0.204 ENST00000370628.2
CD40LG
CD40 ligand
chr7_+_106505912 0.201 ENST00000359195.3
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chrX_+_24167828 0.198 ENST00000379188.3
ENST00000419690.1
ENST00000379177.1
ENST00000304543.5
ZFX



zinc finger protein, X-linked



chr8_+_77593448 0.196 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr9_-_95186739 0.196 ENST00000375550.4
OMD
osteomodulin
chr7_+_106505696 0.192 ENST00000440650.2
ENST00000496166.1
ENST00000473541.1
PIK3CG


phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma


chrX_-_24665353 0.189 ENST00000379144.2
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr3_+_148447887 0.187 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
AGTR1


angiotensin II receptor, type 1


chr22_-_40929812 0.186 ENST00000422851.1
MKL1
megakaryoblastic leukemia (translocation) 1
chr3_-_113897899 0.184 ENST00000383673.2
ENST00000295881.7
DRD3

dopamine receptor D3

chrX_+_135730297 0.180 ENST00000370629.2
CD40LG
CD40 ligand
chr9_+_136287444 0.177 ENST00000355699.2
ENST00000356589.2
ENST00000371911.3
ADAMTS13


ADAM metallopeptidase with thrombospondin type 1 motif, 13


chr5_+_161494770 0.170 ENST00000414552.2
ENST00000361925.4
GABRG2

gamma-aminobutyric acid (GABA) A receptor, gamma 2

chr2_+_204801471 0.165 ENST00000316386.6
ENST00000435193.1
ICOS

inducible T-cell co-stimulator

chr16_-_67517716 0.165 ENST00000290953.2
AGRP
agouti related protein homolog (mouse)
chr12_-_89746173 0.162 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr3_+_137728842 0.161 ENST00000183605.5
CLDN18
claudin 18
chrX_+_99839799 0.145 ENST00000373031.4
TNMD
tenomodulin
chr6_+_7107830 0.140 ENST00000379933.3
RREB1
ras responsive element binding protein 1
chr20_+_62795827 0.138 ENST00000328439.1
ENST00000536311.1
MYT1

myelin transcription factor 1

chr14_+_23299088 0.134 ENST00000355151.5
ENST00000397496.3
ENST00000555345.1
ENST00000432849.3
ENST00000553711.1
ENST00000556465.1
ENST00000397505.2
ENST00000557221.1
ENST00000311892.6
ENST00000556840.1
ENST00000555536.1
MRPL52










mitochondrial ribosomal protein L52










chr17_-_48546324 0.133 ENST00000508540.1
CHAD
chondroadherin
chr2_-_219850277 0.132 ENST00000295727.1
FEV
FEV (ETS oncogene family)
chr4_+_165675269 0.129 ENST00000507311.1
RP11-294O2.2
RP11-294O2.2
chr12_-_21487829 0.128 ENST00000445053.1
ENST00000452078.1
ENST00000458504.1
ENST00000422327.1
ENST00000421294.1
SLCO1A2




solute carrier organic anion transporter family, member 1A2




chr8_+_77593474 0.121 ENST00000455469.2
ENST00000050961.6
ZFHX4

zinc finger homeobox 4

chr8_+_133879193 0.119 ENST00000377869.1
ENST00000220616.4
TG

thyroglobulin

chr6_+_7108210 0.112 ENST00000467782.1
ENST00000334984.6
ENST00000349384.6
RREB1


ras responsive element binding protein 1


chr1_+_74701062 0.111 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr4_-_111119804 0.111 ENST00000394607.3
ENST00000302274.3
ELOVL6

ELOVL fatty acid elongase 6

chr3_+_141106643 0.109 ENST00000514251.1
ZBTB38
zinc finger and BTB domain containing 38
chr5_+_161494521 0.105 ENST00000356592.3
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr17_+_67410832 0.104 ENST00000590474.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr21_-_31588365 0.102 ENST00000399899.1
CLDN8
claudin 8
chr6_+_161123270 0.097 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
PLG


plasminogen


chr6_-_31550192 0.096 ENST00000429299.2
ENST00000446745.2
LTB

lymphotoxin beta (TNF superfamily, member 3)

chr3_-_186080012 0.096 ENST00000544847.1
ENST00000265022.3
DGKG

diacylglycerol kinase, gamma 90kDa

chr2_+_103089756 0.091 ENST00000295269.4
SLC9A4
solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
chr1_+_87797351 0.089 ENST00000370542.1
LMO4
LIM domain only 4
chr1_-_111743285 0.088 ENST00000357640.4
DENND2D
DENN/MADD domain containing 2D
chr5_-_137674000 0.086 ENST00000510119.1
ENST00000513970.1
CDC25C

cell division cycle 25C

chr5_+_32531893 0.083 ENST00000512913.1
SUB1
SUB1 homolog (S. cerevisiae)
chr3_+_160394940 0.082 ENST00000320767.2
ARL14
ADP-ribosylation factor-like 14
chr14_+_56127989 0.081 ENST00000555573.1
KTN1
kinectin 1 (kinesin receptor)
chr4_-_87028478 0.079 ENST00000515400.1
ENST00000395157.3
MAPK10

mitogen-activated protein kinase 10

chr3_-_105588231 0.079 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
CBLB




Cbl proto-oncogene B, E3 ubiquitin protein ligase




chr2_+_162101247 0.078 ENST00000439050.1
ENST00000436506.1
AC009299.3

AC009299.3

chr10_-_32217717 0.078 ENST00000396144.4
ENST00000375245.4
ENST00000344936.2
ENST00000375250.5
ARHGAP12



Rho GTPase activating protein 12



chr5_-_127674883 0.075 ENST00000507835.1
FBN2
fibrillin 2
chr10_+_118350468 0.074 ENST00000358834.4
ENST00000528052.1
ENST00000442761.1
PNLIPRP1


pancreatic lipase-related protein 1


chr2_-_3521518 0.073 ENST00000382093.5
ADI1
acireductone dioxygenase 1
chr5_+_161495038 0.073 ENST00000393933.4
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr17_-_48546232 0.073 ENST00000258969.4
CHAD
chondroadherin
chr17_-_17485731 0.070 ENST00000395783.1
PEMT
phosphatidylethanolamine N-methyltransferase
chr4_-_174256276 0.070 ENST00000296503.5
HMGB2
high mobility group box 2
chr13_-_99910673 0.069 ENST00000397473.2
ENST00000397470.2
GPR18

G protein-coupled receptor 18

chr7_-_99698338 0.067 ENST00000354230.3
ENST00000425308.1
MCM7

minichromosome maintenance complex component 7

chr21_-_31588338 0.059 ENST00000286809.1
CLDN8
claudin 8
chr9_+_105757590 0.059 ENST00000374798.3
ENST00000487798.1
CYLC2

cylicin, basic protein of sperm head cytoskeleton 2

chr15_+_75335604 0.055 ENST00000563393.1
PPCDC
phosphopantothenoylcysteine decarboxylase
chr10_-_81708854 0.052 ENST00000372292.3
SFTPD
surfactant protein D
chr17_+_8924837 0.052 ENST00000173229.2
NTN1
netrin 1
chr6_-_87804815 0.050 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr7_-_107443652 0.049 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
SLC26A3


solute carrier family 26 (anion exchanger), member 3


chr5_-_148758839 0.048 ENST00000261796.3
IL17B
interleukin 17B
chr21_-_38445011 0.045 ENST00000464265.1
ENST00000399102.1
PIGP

phosphatidylinositol glycan anchor biosynthesis, class P

chrX_-_124097620 0.044 ENST00000371130.3
ENST00000422452.2
TENM1

teneurin transmembrane protein 1

chr20_-_55841398 0.043 ENST00000395864.3
BMP7
bone morphogenetic protein 7
chr17_+_9728828 0.041 ENST00000262441.5
GLP2R
glucagon-like peptide 2 receptor
chr6_+_146350267 0.036 ENST00000355289.4
ENST00000282753.1
GRM1

glutamate receptor, metabotropic 1

chr12_-_102872317 0.034 ENST00000424202.2
IGF1
insulin-like growth factor 1 (somatomedin C)
chr2_+_169757750 0.033 ENST00000375363.3
ENST00000429379.2
ENST00000421979.1
G6PC2


glucose-6-phosphatase, catalytic, 2


chr7_+_107384142 0.024 ENST00000440859.3
CBLL1
Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
chr16_-_68034470 0.014 ENST00000412757.2
DPEP2
dipeptidase 2
chr20_-_55841662 0.014 ENST00000395863.3
ENST00000450594.2
BMP7

bone morphogenetic protein 7

chr7_+_129906660 0.010 ENST00000222481.4
CPA2
carboxypeptidase A2 (pancreatic)
chr12_-_68647281 0.010 ENST00000328087.4
ENST00000538666.1
IL22

interleukin 22

chr16_-_86542455 0.008 ENST00000595886.1
ENST00000597578.1
ENST00000593604.1
FENDRR


FOXF1 adjacent non-coding developmental regulatory RNA


chr13_-_49975632 0.007 ENST00000457041.1
ENST00000355854.4
CAB39L

calcium binding protein 39-like

chr7_+_31003621 0.007 ENST00000326139.2
GHRHR
growth hormone releasing hormone receptor
chr12_+_21525818 0.000 ENST00000240652.3
ENST00000542023.1
ENST00000537593.1
IAPP


islet amyloid polypeptide



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
1.2 4.9 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.7 4.6 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.4 1.3 GO:0046521 sphingoid catabolic process(GO:0046521)
0.4 1.6 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.4 1.2 GO:0055005 optic placode formation involved in camera-type eye formation(GO:0046619) ventricular cardiac myofibril assembly(GO:0055005) embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.3 1.0 GO:0035623 renal glucose absorption(GO:0035623)
0.3 1.9 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.2 1.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.2 1.0 GO:0045953 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032) negative regulation of natural killer cell mediated immunity(GO:0002716) negative regulation of natural killer cell mediated cytotoxicity(GO:0045953)
0.2 1.3 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.2 3.9 GO:0006825 copper ion transport(GO:0006825)
0.2 0.5 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.2 4.0 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.2 2.2 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.1 0.4 GO:0000114 obsolete regulation of transcription involved in G1 phase of mitotic cell cycle(GO:0000114)
0.1 0.5 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.1 0.3 GO:0007518 myoblast fate determination(GO:0007518)
0.1 0.4 GO:1904037 positive regulation of epithelial cell apoptotic process(GO:1904037) positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 0.3 GO:0050917 sensory perception of umami taste(GO:0050917)
0.1 0.3 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.3 GO:0010430 ethanol catabolic process(GO:0006068) fatty acid omega-oxidation(GO:0010430)
0.1 4.3 GO:0046324 regulation of glucose import(GO:0046324)
0.1 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.3 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 1.5 GO:0008210 estrogen metabolic process(GO:0008210)
0.1 0.3 GO:0010157 response to chlorate(GO:0010157)
0.1 0.2 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416) negative regulation of sodium ion transmembrane transport(GO:1902306) negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.1 1.4 GO:0045165 cell fate commitment(GO:0045165)
0.1 2.9 GO:0031100 organ regeneration(GO:0031100)
0.1 0.2 GO:0035987 endodermal cell fate commitment(GO:0001711) endodermal cell differentiation(GO:0035987)
0.1 1.8 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of wound healing(GO:0061045) negative regulation of hemostasis(GO:1900047)
0.0 0.2 GO:2000831 renin-angiotensin regulation of aldosterone production(GO:0002018) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) positive regulation of NAD(P)H oxidase activity(GO:0033864) corticosteroid hormone secretion(GO:0035930) mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846) regulation of mineralocorticoid secretion(GO:2000855) regulation of aldosterone secretion(GO:2000858)
0.0 0.4 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.8 GO:0045730 respiratory burst(GO:0045730)
0.0 1.6 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154) negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.0 0.2 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.4 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.1 GO:0042759 fatty acid elongation, saturated fatty acid(GO:0019367) long-chain fatty acid biosynthetic process(GO:0042759)
0.0 2.9 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.5 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 1.1 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.5 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 0.3 GO:0007379 segment specification(GO:0007379)
0.0 0.9 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.1 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.4 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.2 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0046621 negative regulation of organ growth(GO:0046621)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 1.8 GO:0007586 digestion(GO:0007586)
0.0 0.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 1.6 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015) inositol lipid-mediated signaling(GO:0048017)
0.0 0.1 GO:1900087 traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.1 GO:0060346 bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.0 0.7 GO:0007416 synapse assembly(GO:0007416)
0.0 1.7 GO:0007179 transforming growth factor beta receptor signaling pathway(GO:0007179)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.5 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
1.6 4.9 GO:0031904 endosome lumen(GO:0031904)
0.6 4.3 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.2 2.7 GO:0005577 fibrinogen complex(GO:0005577)
0.2 0.5 GO:0032302 MutSbeta complex(GO:0032302)
0.2 1.1 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 2.2 GO:0043034 costamere(GO:0043034)
0.1 0.8 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.8 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 1.0 GO:0045120 pronucleus(GO:0045120)
0.0 0.2 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.3 GO:0016342 catenin complex(GO:0016342)
0.0 0.4 GO:0048786 presynaptic active zone(GO:0048786)
0.0 2.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.9 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 3.3 GO:0005792 obsolete microsome(GO:0005792)
0.0 0.1 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 9.9 GO:0005615 extracellular space(GO:0005615)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.6 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.8 3.9 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.5 6.5 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.4 1.2 GO:0050692 DBD domain binding(GO:0050692)
0.4 4.9 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.2 1.9 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.2 1.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 1.3 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.2 1.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.2 0.5 GO:0000404 heteroduplex DNA loop binding(GO:0000404) double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.1 2.1 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.4 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.9 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.4 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 2.7 GO:0043499 obsolete eukaryotic cell surface binding(GO:0043499)
0.1 0.3 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.5 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 1.0 GO:0031701 angiotensin receptor binding(GO:0031701)
0.1 0.3 GO:0035276 ethanol binding(GO:0035276)
0.1 8.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 2.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.3 GO:0005046 KDEL sequence binding(GO:0005046)
0.1 1.1 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.8 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.2 GO:0010698 angiotensin type I receptor activity(GO:0001596) acetyltransferase activator activity(GO:0010698)
0.1 0.2 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.1 1.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.3 GO:0005113 patched binding(GO:0005113)
0.0 0.5 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.0 0.4 GO:0046934 obsolete inositol or phosphatidylinositol kinase activity(GO:0004428) phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 3.9 GO:0016566 obsolete specific transcriptional repressor activity(GO:0016566)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.3 GO:0042153 obsolete RPTP-like protein binding(GO:0042153) alpha-catenin binding(GO:0045294)
0.0 3.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0004608 phosphatidylethanolamine N-methyltransferase activity(GO:0004608)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922)
0.0 1.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.9 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.0 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.9 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.5 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.4 ST_G_ALPHA_S_PATHWAY G alpha s Pathway