Motif ID: FOXD3_FOXI1_FOXF1

Z-value: 1.844

Transcription factors associated with FOXD3_FOXI1_FOXF1:

Gene SymbolEntrez IDGene Name
FOXD3 ENSG00000187140.4 FOXD3
FOXF1 ENSG00000103241.5 FOXF1
FOXI1 ENSG00000168269.7 FOXI1






Network of associatons between targets according to the STRING database.



First level regulatory network of FOXD3_FOXI1_FOXF1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_111091948 3.142 ENST00000447165.2
NREP
neuronal regeneration related protein
chr3_-_16524357 3.043 ENST00000432519.1
RFTN1
raftlin, lipid raft linker 1
chr18_-_53070913 2.762 ENST00000568186.1
ENST00000564228.1
TCF4

transcription factor 4

chr13_-_47012325 2.574 ENST00000409879.2
KIAA0226L
KIAA0226-like
chr4_-_84035868 2.479 ENST00000426923.2
ENST00000509973.1
PLAC8

placenta-specific 8

chr4_+_68424434 2.377 ENST00000265404.2
ENST00000396225.1
STAP1

signal transducing adaptor family member 1

chr2_-_152146385 2.366 ENST00000414946.1
ENST00000243346.5
NMI

N-myc (and STAT) interactor

chr4_-_84035905 2.329 ENST00000311507.4
PLAC8
placenta-specific 8
chr5_-_88179302 2.324 ENST00000504921.2
MEF2C
myocyte enhancer factor 2C
chr2_-_158345462 2.087 ENST00000439355.1
ENST00000540637.1
CYTIP

cytohesin 1 interacting protein

chr17_-_29641104 1.759 ENST00000577894.1
ENST00000330927.4
EVI2B

ecotropic viral integration site 2B

chr1_+_150122034 1.747 ENST00000025469.6
ENST00000369124.4
PLEKHO1

pleckstrin homology domain containing, family O member 1

chr4_-_105416039 1.655 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr17_-_29641084 1.647 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr10_-_98031265 1.573 ENST00000224337.5
ENST00000371176.2
BLNK

B-cell linker

chr6_-_133084580 1.533 ENST00000525270.1
ENST00000530536.1
ENST00000524919.1
VNN2


vanin 2


chr10_-_98031310 1.527 ENST00000427367.2
ENST00000413476.2
BLNK

B-cell linker

chr12_+_59989791 1.417 ENST00000552432.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr20_+_9494987 1.397 ENST00000427562.2
ENST00000246070.2
LAMP5

lysosomal-associated membrane protein family, member 5

chr3_-_121379739 1.378 ENST00000428394.2
ENST00000314583.3
HCLS1

hematopoietic cell-specific Lyn substrate 1

chr1_-_173174681 1.327 ENST00000367718.1
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr8_-_108510224 1.313 ENST00000517746.1
ENST00000297450.3
ANGPT1

angiopoietin 1

chr15_+_89181974 1.301 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr15_+_89182156 1.274 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr1_-_27952741 1.249 ENST00000399173.1
FGR
feline Gardner-Rasheed sarcoma viral oncogene homolog
chr15_+_89182178 1.245 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr5_-_54281407 1.239 ENST00000381403.4
ESM1
endothelial cell-specific molecule 1
chr1_+_111415757 1.229 ENST00000429072.2
ENST00000271324.5
CD53

CD53 molecule

chr7_+_119913688 1.212 ENST00000331113.4
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr10_-_14050522 1.202 ENST00000342409.2
FRMD4A
FERM domain containing 4A
chr8_+_79428539 1.196 ENST00000352966.5
PKIA
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr12_-_15038779 1.189 ENST00000228938.5
ENST00000539261.1
MGP

matrix Gla protein

chr17_-_46688334 1.159 ENST00000239165.7
HOXB7
homeobox B7
chr18_-_53253323 1.128 ENST00000540999.1
ENST00000563888.2
TCF4

transcription factor 4

chr6_+_114178512 1.127 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr8_-_120685608 1.114 ENST00000427067.2
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr2_+_127413677 1.102 ENST00000356887.7
GYPC
glycophorin C (Gerbich blood group)
chr18_-_53253112 1.096 ENST00000568673.1
ENST00000562847.1
ENST00000568147.1
TCF4


transcription factor 4


chr7_-_144435985 1.071 ENST00000549981.1
TPK1
thiamin pyrophosphokinase 1
chr12_-_49333446 1.044 ENST00000537495.1
AC073610.5
Uncharacterized protein
chr1_+_174844645 1.029 ENST00000486220.1
RABGAP1L
RAB GTPase activating protein 1-like
chr3_-_127455200 1.003 ENST00000398101.3
MGLL
monoglyceride lipase
chrX_+_9431324 0.986 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X





transducin (beta)-like 1X-linked





chr3_-_119278376 0.983 ENST00000478182.1
CD80
CD80 molecule
chr18_-_53089723 0.978 ENST00000561992.1
ENST00000562512.2
TCF4

transcription factor 4

chr10_-_90712520 0.968 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chr10_+_35484793 0.961 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM




cAMP responsive element modulator




chr12_-_92539614 0.960 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr1_+_32739733 0.958 ENST00000333070.4
LCK
lymphocyte-specific protein tyrosine kinase
chr2_+_33661382 0.948 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr6_+_89790490 0.939 ENST00000336032.3
PNRC1
proline-rich nuclear receptor coactivator 1
chr1_+_192544857 0.926 ENST00000367459.3
ENST00000469578.2
RGS1

regulator of G-protein signaling 1

chrX_+_24483338 0.919 ENST00000379162.4
ENST00000441463.2
PDK3

pyruvate dehydrogenase kinase, isozyme 3

chrX_-_70331298 0.910 ENST00000456850.2
ENST00000473378.1
ENST00000487883.1
ENST00000374202.2
IL2RG



interleukin 2 receptor, gamma



chr18_-_53177984 0.900 ENST00000543082.1
TCF4
transcription factor 4
chr7_-_37026108 0.878 ENST00000396045.3
ELMO1
engulfment and cell motility 1
chr3_+_119316689 0.876 ENST00000273371.4
PLA1A
phospholipase A1 member A
chr6_+_31582961 0.874 ENST00000376059.3
ENST00000337917.7
AIF1

allograft inflammatory factor 1

chr6_-_131291572 0.870 ENST00000529208.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr8_-_120651020 0.860 ENST00000522826.1
ENST00000520066.1
ENST00000259486.6
ENST00000075322.6
ENPP2



ectonucleotide pyrophosphatase/phosphodiesterase 2



chr21_-_15918618 0.846 ENST00000400564.1
ENST00000400566.1
SAMSN1

SAM domain, SH3 domain and nuclear localization signals 1

chr3_-_119278446 0.846 ENST00000264246.3
CD80
CD80 molecule
chr2_-_175711133 0.839 ENST00000409597.1
ENST00000413882.1
CHN1

chimerin 1

chr7_-_144533074 0.838 ENST00000360057.3
ENST00000378099.3
TPK1

thiamin pyrophosphokinase 1

chr16_-_24942655 0.837 ENST00000573765.1
ARHGAP17
Rho GTPase activating protein 17
chr14_-_25479811 0.831 ENST00000550887.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr5_-_111093167 0.828 ENST00000446294.2
ENST00000419114.2
NREP

neuronal regeneration related protein

chr13_-_46756351 0.823 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr6_-_152639479 0.810 ENST00000356820.4
SYNE1
spectrin repeat containing, nuclear envelope 1
chr1_-_19811132 0.805 ENST00000433834.1
CAPZB
capping protein (actin filament) muscle Z-line, beta
chr1_-_160681593 0.797 ENST00000368045.3
ENST00000368046.3
CD48

CD48 molecule

chrX_-_154563889 0.770 ENST00000369449.2
ENST00000321926.4
CLIC2

chloride intracellular channel 2

chr6_-_26056695 0.770 ENST00000343677.2
HIST1H1C
histone cluster 1, H1c
chr13_-_46716969 0.770 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr16_-_24942273 0.768 ENST00000571406.1
ARHGAP17
Rho GTPase activating protein 17
chr1_-_57045228 0.765 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr17_+_67498538 0.765 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr15_-_55562582 0.761 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr11_-_73693875 0.752 ENST00000536983.1
UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr6_-_46922659 0.749 ENST00000265417.7
GPR116
G protein-coupled receptor 116
chr3_-_119276575 0.744 ENST00000383669.3
ENST00000383668.3
CD80

CD80 molecule

chr15_-_37390482 0.736 ENST00000559085.1
ENST00000397624.3
MEIS2

Meis homeobox 2

chr13_-_99959641 0.734 ENST00000376414.4
GPR183
G protein-coupled receptor 183
chr3_+_119316721 0.729 ENST00000488919.1
ENST00000495992.1
PLA1A

phospholipase A1 member A

chrX_-_70329118 0.722 ENST00000374188.3
IL2RG
interleukin 2 receptor, gamma
chr3_+_178276488 0.721 ENST00000432997.1
ENST00000455865.1
KCNMB2

potassium large conductance calcium-activated channel, subfamily M, beta member 2

chr6_+_12958137 0.720 ENST00000457702.2
ENST00000379345.2
PHACTR1

phosphatase and actin regulator 1

chr1_-_150669500 0.720 ENST00000271732.3
GOLPH3L
golgi phosphoprotein 3-like
chr11_-_78052923 0.719 ENST00000340149.2
GAB2
GRB2-associated binding protein 2
chr5_+_156712372 0.716 ENST00000541131.1
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr3_-_114035026 0.707 ENST00000570269.1
RP11-553L6.5
RP11-553L6.5
chr13_+_50070077 0.705 ENST00000378319.3
ENST00000426879.1
PHF11

PHD finger protein 11

chr18_+_77160282 0.702 ENST00000318065.5
ENST00000545796.1
ENST00000592223.1
ENST00000329101.4
ENST00000586434.1
NFATC1




nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1




chr14_+_61654271 0.691 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH


protein kinase C, eta


chr10_+_31610064 0.688 ENST00000446923.2
ENST00000559476.1
ZEB1

zinc finger E-box binding homeobox 1

chr12_+_48513009 0.668 ENST00000359794.5
ENST00000551339.1
ENST00000395233.2
ENST00000548345.1
PFKM



phosphofructokinase, muscle



chr14_-_23285011 0.660 ENST00000397532.3
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr7_+_116654935 0.655 ENST00000432298.1
ENST00000422922.1
ST7

suppression of tumorigenicity 7

chr11_-_93276582 0.653 ENST00000298966.2
SMCO4
single-pass membrane protein with coiled-coil domains 4
chr4_-_38806404 0.647 ENST00000308979.2
ENST00000505940.1
ENST00000515861.1
TLR1


toll-like receptor 1


chr1_-_92371839 0.645 ENST00000370399.2
TGFBR3
transforming growth factor, beta receptor III
chr11_+_93479588 0.643 ENST00000526335.1
C11orf54
chromosome 11 open reading frame 54
chr6_-_152489484 0.635 ENST00000354674.4
ENST00000539504.1
SYNE1

spectrin repeat containing, nuclear envelope 1

chr12_-_91576561 0.630 ENST00000547568.2
ENST00000552962.1
DCN

decorin

chr11_-_46142948 0.627 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr17_-_19290483 0.624 ENST00000395592.2
ENST00000299610.4
MFAP4

microfibrillar-associated protein 4

chr12_-_9913489 0.618 ENST00000228434.3
ENST00000536709.1
CD69

CD69 molecule

chr3_-_127541194 0.617 ENST00000453507.2
MGLL
monoglyceride lipase
chr6_+_32812568 0.611 ENST00000414474.1
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr22_-_17680472 0.609 ENST00000330232.4
CECR1
cat eye syndrome chromosome region, candidate 1
chr7_-_86849025 0.608 ENST00000257637.3
TMEM243
transmembrane protein 243, mitochondrial
chr6_+_89790459 0.607 ENST00000369472.1
PNRC1
proline-rich nuclear receptor coactivator 1
chr18_-_53069419 0.606 ENST00000570177.2
TCF4
transcription factor 4
chr3_-_114343039 0.605 ENST00000481632.1
ZBTB20
zinc finger and BTB domain containing 20
chr5_-_94417339 0.603 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
MCTP1


multiple C2 domains, transmembrane 1


chr11_+_65657875 0.596 ENST00000312579.2
CCDC85B
coiled-coil domain containing 85B
chr13_-_99910673 0.596 ENST00000397473.2
ENST00000397470.2
GPR18

G protein-coupled receptor 18

chr7_-_37488834 0.592 ENST00000310758.4
ELMO1
engulfment and cell motility 1
chr14_-_23285069 0.591 ENST00000554758.1
ENST00000397528.4
SLC7A7

solute carrier family 7 (amino acid transporter light chain, y+L system), member 7

chr14_-_92414055 0.590 ENST00000342058.4
FBLN5
fibulin 5
chr4_-_103266626 0.590 ENST00000356736.4
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr14_-_23288930 0.582 ENST00000554517.1
ENST00000285850.7
ENST00000397529.2
ENST00000555702.1
SLC7A7



solute carrier family 7 (amino acid transporter light chain, y+L system), member 7



chr18_-_53303123 0.581 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
TCF4


transcription factor 4


chr2_+_152214098 0.572 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr12_+_59989918 0.572 ENST00000547379.1
ENST00000549465.1
SLC16A7

solute carrier family 16 (monocarboxylate transporter), member 7

chr12_+_10365404 0.560 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABARAPL1





GABA(A) receptor-associated protein like 1





chr2_+_58655461 0.560 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
AC007092.1


long intergenic non-protein coding RNA 1122


chr8_+_70404996 0.552 ENST00000402687.4
ENST00000419716.3
SULF1

sulfatase 1

chr10_-_46030841 0.549 ENST00000453424.2
MARCH8
membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
chr11_+_5710919 0.545 ENST00000379965.3
ENST00000425490.1
TRIM22

tripartite motif containing 22

chr1_+_66797687 0.544 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
PDE4B


phosphodiesterase 4B, cAMP-specific


chr1_+_198608146 0.542 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
PTPRC









protein tyrosine phosphatase, receptor type, C









chr3_+_157154578 0.536 ENST00000295927.3
PTX3
pentraxin 3, long
chr9_-_16727978 0.535 ENST00000418777.1
ENST00000468187.2
BNC2

basonuclin 2

chr1_-_170043709 0.533 ENST00000367767.1
ENST00000361580.2
ENST00000538366.1
KIFAP3


kinesin-associated protein 3


chr3_+_152017360 0.530 ENST00000485910.1
ENST00000463374.1
MBNL1

muscleblind-like splicing regulator 1

chr15_-_55562479 0.523 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr12_-_68696652 0.521 ENST00000539972.1
MDM1
Mdm1 nuclear protein homolog (mouse)
chr8_+_74903580 0.512 ENST00000284818.2
ENST00000518893.1
LY96

lymphocyte antigen 96

chr19_-_11689752 0.501 ENST00000592659.1
ENST00000592828.1
ENST00000218758.5
ENST00000412435.2
ACP5



acid phosphatase 5, tartrate resistant



chr7_+_142985308 0.491 ENST00000310447.5
CASP2
caspase 2, apoptosis-related cysteine peptidase
chr2_-_191878162 0.489 ENST00000540176.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr3_-_105588231 0.483 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
CBLB




Cbl proto-oncogene B, E3 ubiquitin protein ligase




chr11_-_72070206 0.480 ENST00000544382.1
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr4_+_184365744 0.480 ENST00000504169.1
ENST00000302350.4
CDKN2AIP

CDKN2A interacting protein

chr10_-_94003003 0.479 ENST00000412050.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr7_+_120590803 0.474 ENST00000315870.5
ENST00000339121.5
ENST00000445699.1
ING3


inhibitor of growth family, member 3


chr11_-_62323702 0.473 ENST00000530285.1
AHNAK
AHNAK nucleoprotein
chr15_-_55563072 0.472 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A


RAB27A, member RAS oncogene family


chr7_+_28452130 0.471 ENST00000357727.2
CREB5
cAMP responsive element binding protein 5
chr9_+_2029019 0.466 ENST00000382194.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr4_+_26321284 0.466 ENST00000506956.1
ENST00000512671.1
ENST00000345843.3
ENST00000342295.1
RBPJ



recombination signal binding protein for immunoglobulin kappa J region



chr6_-_16761678 0.461 ENST00000244769.4
ENST00000436367.1
ATXN1

ataxin 1

chr1_-_32801825 0.460 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr12_-_15114492 0.455 ENST00000541546.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr1_-_207095324 0.451 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
FAIM3


Fas apoptotic inhibitory molecule 3


chr12_-_15114603 0.450 ENST00000228945.4
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr5_+_68665608 0.446 ENST00000509734.1
ENST00000354868.5
ENST00000521422.1
ENST00000354312.3
ENST00000345306.6
RAD17




RAD17 homolog (S. pombe)




chr5_-_142782862 0.442 ENST00000415690.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr2_+_201994569 0.440 ENST00000457277.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr18_+_32556892 0.436 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
MAPRE2



microtubule-associated protein, RP/EB family, member 2



chr1_+_164528866 0.435 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr4_+_17578815 0.431 ENST00000226299.4
LAP3
leucine aminopeptidase 3
chr12_-_91576429 0.428 ENST00000552145.1
ENST00000546745.1
DCN

decorin

chr12_+_54892550 0.426 ENST00000545638.2
NCKAP1L
NCK-associated protein 1-like
chr7_+_80231466 0.422 ENST00000309881.7
ENST00000534394.1
CD36

CD36 molecule (thrombospondin receptor)

chr14_+_65878565 0.421 ENST00000556518.1
ENST00000557164.1
FUT8

fucosyltransferase 8 (alpha (1,6) fucosyltransferase)

chr12_+_12878829 0.420 ENST00000326765.6
APOLD1
apolipoprotein L domain containing 1
chr11_+_128563948 0.419 ENST00000534087.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr4_+_89378261 0.419 ENST00000264350.3
HERC5
HECT and RLD domain containing E3 ubiquitin protein ligase 5
chr8_-_95449155 0.416 ENST00000481490.2
FSBP
fibrinogen silencer binding protein
chr9_-_20622478 0.407 ENST00000355930.6
ENST00000380338.4
MLLT3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr9_+_2015335 0.405 ENST00000349721.2
ENST00000357248.2
ENST00000450198.1
SMARCA2


SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2


chr1_+_226411319 0.403 ENST00000542034.1
ENST00000366810.5
MIXL1

Mix paired-like homeobox

chr1_-_226926864 0.402 ENST00000429204.1
ENST00000366784.1
ITPKB

inositol-trisphosphate 3-kinase B

chr17_-_37934466 0.399 ENST00000583368.1
IKZF3
IKAROS family zinc finger 3 (Aiolos)
chr4_+_146403912 0.399 ENST00000507367.1
ENST00000394092.2
ENST00000515385.1
SMAD1


SMAD family member 1


chr3_+_141106643 0.392 ENST00000514251.1
ZBTB38
zinc finger and BTB domain containing 38
chr20_-_5093399 0.390 ENST00000379276.4
TMEM230
transmembrane protein 230
chr2_-_231989808 0.389 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr11_-_108093329 0.386 ENST00000278612.8
NPAT
nuclear protein, ataxia-telangiectasia locus
chr20_-_5093673 0.386 ENST00000379299.2
ENST00000379286.2
ENST00000379279.2
ENST00000379283.2
TMEM230



transmembrane protein 230



chr12_-_91574142 0.377 ENST00000547937.1
DCN
decorin
chr6_-_112575912 0.373 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
LAMA4


laminin, alpha 4


chr20_-_5093503 0.373 ENST00000379277.2
TMEM230
transmembrane protein 230
chr20_-_5093713 0.373 ENST00000342308.5
ENST00000202834.7
TMEM230

transmembrane protein 230

chr13_+_76334567 0.372 ENST00000321797.8
LMO7
LIM domain 7
chr3_+_69812877 0.370 ENST00000457080.1
ENST00000328528.6
MITF

microphthalmia-associated transcription factor

chr21_+_30502806 0.370 ENST00000399928.1
ENST00000399926.1
MAP3K7CL

MAP3K7 C-terminal like

chr13_+_76334795 0.368 ENST00000526202.1
ENST00000465261.2
LMO7

LIM domain 7

chr11_+_63304273 0.365 ENST00000439013.2
ENST00000255688.3
RARRES3

retinoic acid receptor responder (tazarotene induced) 3

chr11_+_128563652 0.365 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr7_+_120591170 0.361 ENST00000431467.1
ING3
inhibitor of growth family, member 3
chr8_-_60031762 0.359 ENST00000361421.1
TOX
thymocyte selection-associated high mobility group box
chr15_+_80351910 0.355 ENST00000261749.6
ENST00000561060.1
ZFAND6

zinc finger, AN1-type domain 6

chr6_-_41703952 0.354 ENST00000358871.2
ENST00000403298.4
TFEB

transcription factor EB

chr5_-_24645078 0.353 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr16_+_27438563 0.350 ENST00000395754.4
IL21R
interleukin 21 receptor
chr3_-_49066811 0.349 ENST00000442157.1
ENST00000326739.4
IMPDH2

IMP (inosine 5'-monophosphate) dehydrogenase 2

chr11_-_790060 0.348 ENST00000330106.4
CEND1
cell cycle exit and neuronal differentiation 1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.6 2.6 GO:0060025 regulation of synaptic activity(GO:0060025)
0.6 2.3 GO:0006848 pyruvate transport(GO:0006848)
0.4 2.2 GO:0048014 Tie signaling pathway(GO:0048014)
0.4 1.3 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.4 2.6 GO:0045627 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425) positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.3 1.0 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.3 1.9 GO:0006772 thiamine metabolic process(GO:0006772)
0.3 0.6 GO:0006154 adenosine catabolic process(GO:0006154)
0.3 1.8 GO:0043316 natural killer cell activation involved in immune response(GO:0002323) cytotoxic T cell degranulation(GO:0043316) natural killer cell degranulation(GO:0043320)
0.3 1.7 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.3 0.8 GO:0070340 detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.3 1.6 GO:2000124 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.3 1.6 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.2 0.6 GO:0060318 definitive erythrocyte differentiation(GO:0060318)
0.2 1.8 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.2 1.6 GO:0060100 regulation of phagocytosis, engulfment(GO:0060099) positive regulation of phagocytosis, engulfment(GO:0060100) regulation of membrane invagination(GO:1905153) positive regulation of membrane invagination(GO:1905155)
0.2 0.6 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
0.2 1.6 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.2 0.9 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.2 0.7 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.2 0.5 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.1 1.4 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.7 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.1 0.4 GO:0033578 protein glycosylation in Golgi(GO:0033578)
0.1 0.4 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.1 0.4 GO:0001757 somite specification(GO:0001757)
0.1 0.5 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 0.9 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.7 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 0.5 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.1 1.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.4 GO:0014831 intestine smooth muscle contraction(GO:0014827) gastro-intestinal system smooth muscle contraction(GO:0014831)
0.1 0.5 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 1.4 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.1 0.5 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.1 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.1 0.6 GO:0008228 opsonization(GO:0008228)
0.1 0.5 GO:0071898 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.1 0.3 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.3 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.1 0.5 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 1.5 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 0.6 GO:0019722 calcium-mediated signaling(GO:0019722)
0.1 0.3 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.1 0.8 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1 0.5 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 0.7 GO:0043931 ossification involved in bone maturation(GO:0043931)
0.1 0.6 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.4 GO:0045759 negative regulation of action potential(GO:0045759)
0.1 0.3 GO:1903961 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) positive regulation of anion transmembrane transport(GO:1903961)
0.1 0.2 GO:0006816 calcium ion transport(GO:0006816)
0.1 0.3 GO:0030101 natural killer cell activation(GO:0030101)
0.1 0.1 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.1 0.8 GO:0008354 germ cell migration(GO:0008354)
0.1 0.4 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.1 0.4 GO:0010771 negative regulation of cell morphogenesis involved in differentiation(GO:0010771)
0.1 0.2 GO:0090598 male genitalia morphogenesis(GO:0048808) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) male anatomical structure morphogenesis(GO:0090598)
0.1 0.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 1.4 GO:0006911 phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.1 0.2 GO:0019695 choline metabolic process(GO:0019695)
0.1 0.2 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
0.1 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 8.5 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 0.9 GO:0019228 neuronal action potential(GO:0019228)
0.1 0.2 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 0.5 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 0.2 GO:0007285 primary spermatocyte growth(GO:0007285)
0.1 0.1 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.1 0.3 GO:0071168 protein localization to chromatin(GO:0071168)
0.1 0.7 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.1 1.1 GO:0001502 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.1 0.1 GO:0050766 regulation of phagocytosis(GO:0050764) positive regulation of phagocytosis(GO:0050766)
0.1 0.3 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.4 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 1.6 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.1 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.1 GO:0072678 T cell chemotaxis(GO:0010818) regulation of T cell chemotaxis(GO:0010819) positive regulation of T cell chemotaxis(GO:0010820) T cell migration(GO:0072678) regulation of lymphocyte chemotaxis(GO:1901623) regulation of lymphocyte migration(GO:2000401) positive regulation of lymphocyte migration(GO:2000403) regulation of T cell migration(GO:2000404) positive regulation of T cell migration(GO:2000406)
0.1 0.1 GO:0046639 negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.1 0.2 GO:0009106 lipoate metabolic process(GO:0009106)
0.1 1.3 GO:0050830 defense response to Gram-positive bacterium(GO:0050830)
0.1 0.2 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.1 0.4 GO:0001554 luteolysis(GO:0001554)
0.1 0.6 GO:0000076 DNA replication checkpoint(GO:0000076)
0.1 1.1 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.1 0.5 GO:0071692 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.2 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162) pyrimidine deoxyribonucleoside monophosphate metabolic process(GO:0009176) dUMP metabolic process(GO:0046078)
0.0 0.3 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.3 GO:0070245 positive regulation of T cell apoptotic process(GO:0070234) positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.2 GO:0090025 regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0 2.7 GO:0097696 JAK-STAT cascade(GO:0007259) STAT cascade(GO:0097696)
0.0 1.2 GO:0001508 action potential(GO:0001508)
0.0 0.3 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.5 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0045953 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032) negative regulation of natural killer cell mediated immunity(GO:0002716) negative regulation of natural killer cell mediated cytotoxicity(GO:0045953)
0.0 0.8 GO:0000303 response to superoxide(GO:0000303)
0.0 0.4 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.6 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.8 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.2 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 1.1 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.1 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.3 GO:0031274 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0030202 heparin metabolic process(GO:0030202)
0.0 2.1 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.3 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 1.1 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.2 GO:0009128 AMP catabolic process(GO:0006196) nucleoside monophosphate catabolic process(GO:0009125) purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.2 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.2 GO:0042635 positive regulation of hair cycle(GO:0042635) regulation of hair follicle development(GO:0051797) positive regulation of hair follicle development(GO:0051798)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 2.4 GO:0061025 membrane fusion(GO:0061025)
0.0 0.5 GO:0009154 cAMP catabolic process(GO:0006198) purine ribonucleotide catabolic process(GO:0009154)
0.0 0.6 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.3 GO:0031000 response to caffeine(GO:0031000)
0.0 0.1 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0 0.1 GO:0009301 snRNA transcription(GO:0009301)
0.0 0.7 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.6 GO:1902749 regulation of G2/M transition of mitotic cell cycle(GO:0010389) regulation of cell cycle G2/M phase transition(GO:1902749)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.0 0.2 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.9 GO:0050931 melanocyte differentiation(GO:0030318) pigment cell differentiation(GO:0050931)
0.0 0.3 GO:0050856 regulation of T cell receptor signaling pathway(GO:0050856)
0.0 0.4 GO:0070206 protein trimerization(GO:0070206)
0.0 0.1 GO:0071462 cellular response to water stimulus(GO:0071462)
0.0 0.2 GO:0007346 regulation of mitotic cell cycle(GO:0007346)
0.0 0.0 GO:0032060 bleb assembly(GO:0032060)
0.0 0.2 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.8 GO:0051693 actin filament capping(GO:0051693)
0.0 0.1 GO:0071635 negative regulation of transforming growth factor beta production(GO:0071635)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.0 GO:0032693 tolerance induction to self antigen(GO:0002513) regulation of chronic inflammatory response(GO:0002676) negative regulation of chronic inflammatory response(GO:0002677) negative regulation of interleukin-10 production(GO:0032693) positive regulation of immature T cell proliferation(GO:0033091)
0.0 0.2 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.1 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.3 GO:0045954 positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.1 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.0 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0006386 transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0 1.0 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.2 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 0.1 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.3 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.3 GO:0048661 positive regulation of smooth muscle cell proliferation(GO:0048661)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.0 GO:0010430 ethanol catabolic process(GO:0006068) fatty acid omega-oxidation(GO:0010430)
0.0 0.1 GO:0032414 positive regulation of ion transmembrane transporter activity(GO:0032414)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 0.2 GO:0071496 cellular response to external stimulus(GO:0071496)
0.0 0.9 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 0.3 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.2 GO:0051924 regulation of calcium ion transport(GO:0051924)
0.0 0.1 GO:0015793 glycerol transport(GO:0015793)
0.0 0.1 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.0 1.3 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) positive regulation of cell cycle arrest(GO:0071158) signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.0 0.1 GO:1902170 cellular response to nitric oxide(GO:0071732) cellular response to reactive nitrogen species(GO:1902170)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815) beta-amyloid metabolic process(GO:0050435)
0.0 0.1 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.5 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.0 0.0 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.3 GO:0000080 mitotic G1 phase(GO:0000080)
0.0 0.2 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280) negative regulation of lyase activity(GO:0051350)
0.0 0.5 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.0 0.1 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 0.8 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.6 GO:0017156 calcium ion regulated exocytosis(GO:0017156)
0.0 0.8 GO:0006968 cellular defense response(GO:0006968)
0.0 0.2 GO:0070374 positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.0 0.0 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.0 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.1 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.4 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 0.0 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367) regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.1 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.0 2.0 GO:0050900 leukocyte migration(GO:0050900)
0.0 0.0 GO:1901142 insulin processing(GO:0030070) insulin metabolic process(GO:1901142)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.2 1.6 GO:0001891 phagocytic cup(GO:0001891)
0.2 0.8 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 0.6 GO:0071953 elastic fiber(GO:0071953)
0.2 0.5 GO:0001652 granular component(GO:0001652)
0.1 0.5 GO:0016939 kinesin II complex(GO:0016939)
0.1 1.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.7 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 1.4 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.4 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.3 GO:0043159 acrosomal matrix(GO:0043159)
0.1 0.5 GO:0042405 nuclear RNA export factor complex(GO:0042272) nuclear inclusion body(GO:0042405)
0.1 1.1 GO:0005606 laminin-1 complex(GO:0005606)
0.1 1.2 GO:0043073 germ cell nucleus(GO:0043073)
0.1 1.0 GO:0000242 pericentriolar material(GO:0000242)
0.1 0.6 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.3 GO:0008278 cohesin complex(GO:0008278)
0.1 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.9 GO:0008091 spectrin(GO:0008091)
0.1 0.8 GO:0071778 obsolete WINAC complex(GO:0071778)
0.1 0.8 GO:0071203 F-actin capping protein complex(GO:0008290) WASH complex(GO:0071203)
0.0 0.2 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.2 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.0 0.1 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0 0.5 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 1.1 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 2.1 GO:0016605 PML body(GO:0016605)
0.0 0.4 GO:0001527 microfibril(GO:0001527)
0.0 0.3 GO:0032040 small-subunit processome(GO:0032040)
0.0 1.7 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 1.2 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 4.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.8 GO:0045202 synapse(GO:0045202)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.3 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.2 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.0 GO:0005903 brush border(GO:0005903) cluster of actin-based cell projections(GO:0098862)
0.0 1.1 GO:0015030 Cajal body(GO:0015030)
0.0 3.7 GO:0030425 dendrite(GO:0030425)
0.0 1.3 GO:0043197 dendritic spine(GO:0043197)
0.0 1.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 3.1 GO:0005769 early endosome(GO:0005769)
0.0 0.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.6 GO:0005776 autophagosome(GO:0005776)
0.0 0.5 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0000796 condensin complex(GO:0000796)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.5 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.4 GO:0030175 filopodium(GO:0030175)
0.0 5.3 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.6 GO:0005902 microvillus(GO:0005902)
0.0 0.0 GO:0016600 flotillin complex(GO:0016600)
0.0 0.7 GO:0044815 nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.0 0.3 GO:0031105 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0030897 HOPS complex(GO:0030897)
0.0 1.1 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:0045120 pronucleus(GO:0045120)
0.0 0.6 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.3 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0042599 lamellar body(GO:0042599)
0.0 0.2 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.1 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.1 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 1.4 GO:0016607 nuclear speck(GO:0016607)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) exoribonuclease II activity(GO:0008859)
0.7 2.0 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.6 8.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093)
0.6 2.3 GO:0050833 pyruvate secondary active transmembrane transporter activity(GO:0005477) pyruvate transmembrane transporter activity(GO:0050833)
0.5 1.6 GO:0004917 interleukin-4 receptor activity(GO:0004913) interleukin-7 receptor activity(GO:0004917) interleukin-2 binding(GO:0019976)
0.5 1.6 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.3 1.0 GO:0042610 CD8 receptor binding(GO:0042610)
0.3 1.5 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.2 1.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 2.9 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 1.9 GO:0016778 diphosphotransferase activity(GO:0016778)
0.2 0.9 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 1.8 GO:0031489 myosin V binding(GO:0031489)
0.2 1.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.2 0.5 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.2 0.5 GO:0000150 recombinase activity(GO:0000150)
0.2 0.3 GO:0050681 androgen receptor binding(GO:0050681)
0.1 0.4 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.1 0.7 GO:0004883 glucocorticoid receptor activity(GO:0004883)
0.1 0.5 GO:0035326 enhancer binding(GO:0035326)
0.1 0.8 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.4 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 1.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.9 GO:0042731 PH domain binding(GO:0042731)
0.1 0.8 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.6 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 0.7 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.3 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.1 1.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 3.5 GO:0015026 coreceptor activity(GO:0015026)
0.1 0.3 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.1 0.3 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 0.9 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 1.4 GO:0005521 lamin binding(GO:0005521)
0.1 0.3 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.3 GO:0008907 integrase activity(GO:0008907)
0.1 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.3 GO:0033265 choline binding(GO:0033265)
0.1 0.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.6 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.2 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.1 0.2 GO:0004796 thromboxane-A synthase activity(GO:0004796)
0.1 0.4 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.1 0.3 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.1 0.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.2 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.2 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 1.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.3 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.6 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.2 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1 0.9 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.2 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.1 0.2 GO:0050062 long-chain-fatty-acyl-CoA reductase activity(GO:0050062)
0.1 0.2 GO:0071723 lipopeptide binding(GO:0071723)
0.1 0.4 GO:0031432 titin binding(GO:0031432)
0.0 0.4 GO:0005497 androgen binding(GO:0005497)
0.0 0.3 GO:0031404 chloride ion binding(GO:0031404)
0.0 1.4 GO:1990782 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0 1.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.9 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.4 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 1.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.5 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.3 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.5 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 1.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 5.2 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0070260 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.0 0.1 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.0 2.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.6 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.4 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 1.2 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.4 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.2 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 1.6 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.6 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.3 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.3 GO:0016896 exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0 0.2 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 1.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.0 0.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0070492 sialic acid binding(GO:0033691) oligosaccharide binding(GO:0070492)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.3 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.6 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 1.3 GO:0051015 actin filament binding(GO:0051015)
0.0 1.5 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.0 GO:0035276 ethanol binding(GO:0035276)
0.0 0.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.4 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 0.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.7 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.1 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.7 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 1.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.6 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.3 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 0.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.1 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.1 GO:0001228 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0017091 AU-rich element binding(GO:0017091)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.1 3.0 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.5 ST_INTERLEUKIN_4_PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.7 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.4 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.0 2.0 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.0 0.5 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.2 ST_ADRENERGIC Adrenergic Pathway
0.0 0.7 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.2 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 0.3 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.