Motif ID: FOXK1_FOXP2_FOXB1_FOXP3

Z-value: 2.395







Network of associatons between targets according to the STRING database.



First level regulatory network of FOXK1_FOXP2_FOXB1_FOXP3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_134551583 8.782 ENST00000435928.1
CALD1
caldesmon 1
chr10_-_101841588 8.562 ENST00000370418.3
CPN1
carboxypeptidase N, polypeptide 1
chr5_-_42811986 7.859 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1


selenoprotein P, plasma, 1


chr5_-_42812143 7.698 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chr12_-_9268707 7.341 ENST00000318602.7
A2M
alpha-2-macroglobulin
chr1_-_161193349 6.705 ENST00000469730.2
ENST00000463273.1
ENST00000464492.1
ENST00000367990.3
ENST00000470459.2
ENST00000468465.1
ENST00000463812.1
APOA2






apolipoprotein A-II






chr17_-_64225508 6.373 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr10_-_52645379 6.069 ENST00000395489.2
A1CF
APOBEC1 complementation factor
chr7_+_134464414 5.895 ENST00000361901.2
CALD1
caldesmon 1
chr10_-_52645416 5.830 ENST00000374001.2
ENST00000373997.3
ENST00000373995.3
ENST00000282641.2
ENST00000395495.1
ENST00000414883.1
A1CF





APOBEC1 complementation factor





chr17_+_72426891 5.528 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr2_-_188419078 5.447 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
TFPI



tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)



chr10_+_123923105 5.335 ENST00000368999.1
TACC2
transforming, acidic coiled-coil containing protein 2
chr2_-_188419200 5.097 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
TFPI



tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)



chr17_-_7018128 4.611 ENST00000380952.2
ENST00000254850.7
ASGR2

asialoglycoprotein receptor 2

chr17_-_7017968 4.595 ENST00000355035.5
ASGR2
asialoglycoprotein receptor 2
chr17_-_64216748 4.487 ENST00000585162.1
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr7_+_134464376 4.478 ENST00000454108.1
ENST00000361675.2
CALD1

caldesmon 1

chr7_+_134576317 4.397 ENST00000424922.1
ENST00000495522.1
CALD1

caldesmon 1

chr11_-_115375107 4.322 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1





cell adhesion molecule 1





chr10_+_123922941 4.248 ENST00000360561.3
TACC2
transforming, acidic coiled-coil containing protein 2
chr10_+_123923205 3.977 ENST00000369004.3
ENST00000260733.3
TACC2

transforming, acidic coiled-coil containing protein 2

chr7_-_87342564 3.751 ENST00000265724.3
ENST00000416177.1
ABCB1

ATP-binding cassette, sub-family B (MDR/TAP), member 1

chr17_+_72427477 3.564 ENST00000342648.5
ENST00000481232.1
GPRC5C

G protein-coupled receptor, family C, group 5, member C

chr10_+_114710211 3.556 ENST00000349937.2
ENST00000369397.4
TCF7L2

transcription factor 7-like 2 (T-cell specific, HMG-box)

chr2_-_165424973 3.478 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chr3_-_114477787 3.314 ENST00000464560.1
ZBTB20
zinc finger and BTB domain containing 20
chr12_-_71551652 3.310 ENST00000546561.1
TSPAN8
tetraspanin 8
chr11_+_844406 3.256 ENST00000397404.1
TSPAN4
tetraspanin 4
chr17_-_7082668 3.224 ENST00000573083.1
ENST00000574388.1
ASGR1

asialoglycoprotein receptor 1

chr10_+_7745303 3.207 ENST00000429820.1
ENST00000379587.4
ITIH2

inter-alpha-trypsin inhibitor heavy chain 2

chr14_+_21156915 3.203 ENST00000397990.4
ENST00000555597.1
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr1_-_27240455 3.190 ENST00000254227.3
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr4_+_74269956 3.150 ENST00000295897.4
ENST00000415165.2
ENST00000503124.1
ENST00000509063.1
ENST00000401494.3
ALB




albumin




chr11_+_101983176 3.116 ENST00000524575.1
YAP1
Yes-associated protein 1
chr4_-_186456652 3.093 ENST00000284767.5
ENST00000284770.5
PDLIM3

PDZ and LIM domain 3

chr7_+_134430212 2.997 ENST00000436461.2
CALD1
caldesmon 1
chr10_+_114710425 2.993 ENST00000352065.5
ENST00000369395.1
TCF7L2

transcription factor 7-like 2 (T-cell specific, HMG-box)

chr5_-_16742330 2.941 ENST00000505695.1
ENST00000427430.2
MYO10

myosin X

chr10_+_114709999 2.869 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
TCF7L2






transcription factor 7-like 2 (T-cell specific, HMG-box)






chr12_-_91574142 2.799 ENST00000547937.1
DCN
decorin
chr1_+_207277590 2.771 ENST00000367070.3
C4BPA
complement component 4 binding protein, alpha
chr18_-_25616519 2.759 ENST00000399380.3
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr14_-_25479811 2.740 ENST00000550887.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr4_-_110723134 2.738 ENST00000510800.1
ENST00000512148.1
CFI

complement factor I

chr3_-_114477962 2.732 ENST00000471418.1
ZBTB20
zinc finger and BTB domain containing 20
chr9_+_124048864 2.724 ENST00000545652.1
GSN
gelsolin
chr12_+_13349650 2.646 ENST00000256951.5
ENST00000431267.2
ENST00000542474.1
ENST00000544053.1
EMP1



epithelial membrane protein 1



chr4_-_186456766 2.622 ENST00000284771.6
PDLIM3
PDZ and LIM domain 3
chr12_+_100867486 2.600 ENST00000548884.1
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr3_+_186330712 2.577 ENST00000411641.2
ENST00000273784.5
AHSG

alpha-2-HS-glycoprotein

chr4_-_186733363 2.571 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2


sorbin and SH3 domain containing 2


chr10_-_90751038 2.565 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
ACTA2


actin, alpha 2, smooth muscle, aorta


chr11_+_844067 2.529 ENST00000397406.1
ENST00000409543.2
ENST00000525201.1
TSPAN4


tetraspanin 4


chr11_+_46402297 2.517 ENST00000405308.2
MDK
midkine (neurite growth-promoting factor 2)
chr12_+_100867694 2.486 ENST00000392986.3
ENST00000549996.1
NR1H4

nuclear receptor subfamily 1, group H, member 4

chr7_-_95064264 2.402 ENST00000536183.1
ENST00000433091.2
ENST00000222572.3
PON2


paraoxonase 2


chr4_-_110723194 2.379 ENST00000394635.3
CFI
complement factor I
chr14_-_94789663 2.374 ENST00000557225.1
ENST00000341584.3
SERPINA6

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6

chr19_+_18496957 2.370 ENST00000252809.3
GDF15
growth differentiation factor 15
chr12_-_71551868 2.344 ENST00000247829.3
TSPAN8
tetraspanin 8
chr2_+_163175394 2.320 ENST00000446271.1
ENST00000429691.2
GCA

grancalcin, EF-hand calcium binding protein

chr18_+_3449695 2.305 ENST00000343820.5
TGIF1
TGFB-induced factor homeobox 1
chr11_+_46402482 2.276 ENST00000441869.1
MDK
midkine (neurite growth-promoting factor 2)
chr1_+_207262881 2.253 ENST00000451804.2
C4BPB
complement component 4 binding protein, beta
chr2_+_177053307 2.223 ENST00000331462.4
HOXD1
homeobox D1
chr9_-_94124171 2.215 ENST00000422391.2
ENST00000375731.4
ENST00000303617.5
AUH


AU RNA binding protein/enoyl-CoA hydratase


chr2_+_97481974 2.188 ENST00000377060.3
ENST00000305510.3
CNNM3

cyclin M3

chr18_+_29171689 2.142 ENST00000237014.3
TTR
transthyretin
chr3_-_185826855 2.136 ENST00000306376.5
ETV5
ets variant 5
chr17_+_26662730 2.129 ENST00000226225.2
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr12_+_66217911 2.103 ENST00000403681.2
HMGA2
high mobility group AT-hook 2
chr10_+_31610064 2.081 ENST00000446923.2
ENST00000559476.1
ZEB1

zinc finger E-box binding homeobox 1

chrX_+_146993534 2.041 ENST00000334557.6
ENST00000439526.2
ENST00000370475.4
FMR1


fragile X mental retardation 1


chr20_+_306177 2.028 ENST00000544632.1
SOX12
SRY (sex determining region Y)-box 12
chr11_-_111781554 2.002 ENST00000526167.1
ENST00000528961.1
CRYAB

crystallin, alpha B

chr8_+_70404996 1.994 ENST00000402687.4
ENST00000419716.3
SULF1

sulfatase 1

chr2_+_201170596 1.982 ENST00000439084.1
ENST00000409718.1
SPATS2L

spermatogenesis associated, serine-rich 2-like

chr10_-_69597915 1.972 ENST00000225171.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr3_-_123512688 1.945 ENST00000475616.1
MYLK
myosin light chain kinase
chr1_-_12677714 1.911 ENST00000376223.2
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr11_-_111781610 1.898 ENST00000525823.1
CRYAB
crystallin, alpha B
chr1_-_169555779 1.897 ENST00000367797.3
ENST00000367796.3
F5

coagulation factor V (proaccelerin, labile factor)

chr4_-_70080449 1.891 ENST00000446444.1
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr18_+_55888767 1.871 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L


neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase


chr20_-_43150601 1.863 ENST00000541235.1
ENST00000255175.1
ENST00000342374.4
SERINC3


serine incorporator 3


chr20_-_50384864 1.853 ENST00000311637.5
ENST00000402822.1
ATP9A

ATPase, class II, type 9A

chr10_+_5135981 1.845 ENST00000380554.3
AKR1C3
aldo-keto reductase family 1, member C3
chr16_+_72088376 1.841 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
HP








HPR
haptoglobin








haptoglobin-related protein
chr2_-_190927447 1.787 ENST00000260950.4
MSTN
myostatin
chrX_-_20236970 1.714 ENST00000379548.4
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr3_-_148939835 1.712 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr6_+_89791507 1.711 ENST00000354922.3
PNRC1
proline-rich nuclear receptor coactivator 1
chr4_-_155533787 1.709 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
FGG





fibrinogen gamma chain





chr16_-_87970122 1.694 ENST00000309893.2
CA5A
carbonic anhydrase VA, mitochondrial
chr17_+_79953310 1.688 ENST00000582355.2
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr4_-_89744457 1.683 ENST00000395002.2
FAM13A
family with sequence similarity 13, member A
chr10_-_45474237 1.678 ENST00000448778.1
ENST00000298295.3
C10orf10

chromosome 10 open reading frame 10

chr6_-_41715128 1.672 ENST00000356667.4
ENST00000373025.3
ENST00000425343.2
PGC


progastricsin (pepsinogen C)


chrX_-_10851762 1.666 ENST00000380785.1
ENST00000380787.1
MID1

midline 1 (Opitz/BBB syndrome)

chr13_-_67802549 1.663 ENST00000328454.5
ENST00000377865.2
PCDH9

protocadherin 9

chr1_+_229440129 1.647 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr2_+_11674213 1.637 ENST00000381486.2
GREB1
growth regulation by estrogen in breast cancer 1
chr3_+_133465228 1.634 ENST00000482271.1
ENST00000264998.3
TF

transferrin

chr4_+_74275057 1.629 ENST00000511370.1
ALB
albumin
chr4_-_186732048 1.601 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2




sorbin and SH3 domain containing 2




chr11_+_117073850 1.599 ENST00000529622.1
TAGLN
transgelin
chr7_+_106809406 1.598 ENST00000468410.1
ENST00000478930.1
ENST00000464009.1
ENST00000222574.4
HBP1



HMG-box transcription factor 1



chr2_+_189839046 1.590 ENST00000304636.3
ENST00000317840.5
COL3A1

collagen, type III, alpha 1

chr12_-_111926342 1.586 ENST00000389154.3
ATXN2
ataxin 2
chr2_-_190044480 1.579 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr10_+_7745232 1.579 ENST00000358415.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr9_+_504674 1.568 ENST00000382297.2
KANK1
KN motif and ankyrin repeat domains 1
chr12_+_96588143 1.539 ENST00000228741.3
ENST00000547249.1
ELK3

ELK3, ETS-domain protein (SRF accessory protein 2)

chr3_+_158787041 1.532 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1


IQCJ-SCHIP1 readthrough


chr8_-_119124045 1.512 ENST00000378204.2
EXT1
exostosin glycosyltransferase 1
chr1_-_57431679 1.512 ENST00000371237.4
ENST00000535057.1
ENST00000543257.1
C8B


complement component 8, beta polypeptide


chr5_-_78281603 1.511 ENST00000264914.4
ARSB
arylsulfatase B
chr10_-_92681033 1.499 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr7_+_134576151 1.497 ENST00000393118.2
CALD1
caldesmon 1
chr9_-_116840728 1.493 ENST00000265132.3
AMBP
alpha-1-microglobulin/bikunin precursor
chr17_-_7082861 1.483 ENST00000269299.3
ASGR1
asialoglycoprotein receptor 1
chr13_-_41240717 1.482 ENST00000379561.5
FOXO1
forkhead box O1
chr6_+_123110465 1.478 ENST00000539041.1
SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr6_-_52859046 1.468 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
GSTA4


glutathione S-transferase alpha 4


chr12_-_91539918 1.466 ENST00000548218.1
DCN
decorin
chr6_-_56707943 1.464 ENST00000370769.4
ENST00000421834.2
ENST00000312431.6
ENST00000361203.3
ENST00000523817.1
DST




dystonin




chr1_+_207262540 1.462 ENST00000452902.2
C4BPB
complement component 4 binding protein, beta
chr1_-_57045228 1.461 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr4_+_155484155 1.459 ENST00000509493.1
FGB
fibrinogen beta chain
chr16_-_84150492 1.458 ENST00000343411.3
MBTPS1
membrane-bound transcription factor peptidase, site 1
chr17_+_26662597 1.458 ENST00000544907.2
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr2_+_201450591 1.455 ENST00000374700.2
AOX1
aldehyde oxidase 1
chrX_-_128657457 1.452 ENST00000371121.3
ENST00000371123.1
ENST00000371122.4
SMARCA1


SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1


chr3_-_185538849 1.452 ENST00000421047.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr10_+_111985713 1.449 ENST00000239007.7
MXI1
MAX interactor 1, dimerization protein
chr12_-_103310987 1.446 ENST00000307000.2
PAH
phenylalanine hydroxylase
chr13_+_73629107 1.442 ENST00000539231.1
KLF5
Kruppel-like factor 5 (intestinal)
chr8_-_13372395 1.440 ENST00000276297.4
ENST00000511869.1
DLC1

deleted in liver cancer 1

chr2_-_163099885 1.431 ENST00000443424.1
FAP
fibroblast activation protein, alpha
chr11_-_111781454 1.414 ENST00000533280.1
CRYAB
crystallin, alpha B
chr3_-_149093499 1.411 ENST00000472441.1
TM4SF1
transmembrane 4 L six family member 1
chr4_+_124317940 1.390 ENST00000505319.1
ENST00000339241.1
SPRY1

sprouty homolog 1, antagonist of FGF signaling (Drosophila)

chr1_-_109935819 1.386 ENST00000538502.1
SORT1
sortilin 1
chr1_+_214161854 1.386 ENST00000435016.1
PROX1
prospero homeobox 1
chr21_-_43735446 1.383 ENST00000398431.2
TFF3
trefoil factor 3 (intestinal)
chr2_-_88427568 1.381 ENST00000393750.3
ENST00000295834.3
FABP1

fatty acid binding protein 1, liver

chr1_+_100111479 1.372 ENST00000263174.4
PALMD
palmdelphin
chr22_+_21128167 1.367 ENST00000215727.5
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr2_-_163100045 1.367 ENST00000188790.4
FAP
fibroblast activation protein, alpha
chr15_+_81071684 1.358 ENST00000220244.3
ENST00000394685.3
ENST00000356249.5
KIAA1199


KIAA1199


chr17_+_66521936 1.350 ENST00000592800.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr9_-_135819987 1.346 ENST00000298552.3
ENST00000403810.1
TSC1

tuberous sclerosis 1

chr16_+_14980632 1.340 ENST00000565655.1
NOMO1
NODAL modulator 1
chr12_+_53491220 1.338 ENST00000548547.1
ENST00000301464.3
IGFBP6

insulin-like growth factor binding protein 6

chr1_+_207262170 1.332 ENST00000367078.3
C4BPB
complement component 4 binding protein, beta
chr1_+_162602244 1.328 ENST00000367922.3
ENST00000367921.3
DDR2

discoidin domain receptor tyrosine kinase 2

chr1_-_153599732 1.314 ENST00000392623.1
S100A13
S100 calcium binding protein A13
chr20_+_44519948 1.308 ENST00000354880.5
ENST00000191018.5
CTSA

cathepsin A

chr20_+_306221 1.306 ENST00000342665.2
SOX12
SRY (sex determining region Y)-box 12
chr1_+_207262627 1.306 ENST00000391923.1
C4BPB
complement component 4 binding protein, beta
chr2_+_192141611 1.283 ENST00000392316.1
MYO1B
myosin IB
chr8_-_27472198 1.282 ENST00000519472.1
ENST00000523589.1
ENST00000522413.1
ENST00000523396.1
ENST00000560366.1
CLU




clusterin




chr3_+_190333097 1.267 ENST00000412080.1
IL1RAP
interleukin 1 receptor accessory protein
chrX_-_132887729 1.259 ENST00000406757.2
GPC3
glypican 3
chr4_+_166300084 1.259 ENST00000402744.4
CPE
carboxypeptidase E
chr11_-_116708302 1.250 ENST00000375320.1
ENST00000359492.2
ENST00000375329.2
ENST00000375323.1
APOA1



apolipoprotein A-I



chr10_-_69597810 1.247 ENST00000483798.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chrX_+_105937068 1.242 ENST00000324342.3
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr4_-_70361615 1.241 ENST00000305107.6
UGT2B4
UDP glucuronosyltransferase 2 family, polypeptide B4
chr17_+_58755184 1.227 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3


breast carcinoma amplified sequence 3


chr2_-_175711133 1.222 ENST00000409597.1
ENST00000413882.1
CHN1

chimerin 1

chr14_-_53331239 1.220 ENST00000553663.1
FERMT2
fermitin family member 2
chr7_+_102553430 1.211 ENST00000339431.4
ENST00000249377.4
LRRC17

leucine rich repeat containing 17

chr20_+_44520009 1.209 ENST00000607482.1
ENST00000372459.2
CTSA

cathepsin A

chr13_+_102142296 1.207 ENST00000376162.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr12_-_91576561 1.202 ENST00000547568.2
ENST00000552962.1
DCN

decorin

chr12_-_96390063 1.202 ENST00000541929.1
HAL
histidine ammonia-lyase
chr2_+_228678550 1.195 ENST00000409189.3
ENST00000358813.4
CCL20

chemokine (C-C motif) ligand 20

chr16_-_75467318 1.189 ENST00000283882.3
CFDP1
craniofacial development protein 1
chr11_-_18258342 1.177 ENST00000278222.4
SAA4
serum amyloid A4, constitutive
chr2_+_201171242 1.176 ENST00000360760.5
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr3_-_99569821 1.173 ENST00000487087.1
FILIP1L
filamin A interacting protein 1-like
chr10_-_93392811 1.172 ENST00000238994.5
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr20_+_44035200 1.165 ENST00000372717.1
ENST00000360981.4
DBNDD2

dysbindin (dystrobrevin binding protein 1) domain containing 2

chr14_-_74551172 1.161 ENST00000553458.1
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr20_-_22566089 1.150 ENST00000377115.4
FOXA2
forkhead box A2
chr11_-_35287243 1.147 ENST00000464522.2
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr3_+_147127142 1.142 ENST00000282928.4
ZIC1
Zic family member 1
chr5_+_34757309 1.140 ENST00000397449.1
RAI14
retinoic acid induced 14
chr8_+_97597148 1.136 ENST00000521590.1
SDC2
syndecan 2
chr4_+_74301880 1.134 ENST00000395792.2
ENST00000226359.2
AFP

alpha-fetoprotein

chr14_+_24583836 1.122 ENST00000559115.1
ENST00000558215.1
ENST00000557810.1
ENST00000561375.1
ENST00000446197.3
ENST00000559796.1
ENST00000560713.1
ENST00000560901.1
ENST00000559382.1
DCAF11








DDB1 and CUL4 associated factor 11








chrX_+_37208540 1.118 ENST00000466533.1
ENST00000542554.1
ENST00000543642.1
ENST00000484460.1
ENST00000449135.2
ENST00000463135.1
ENST00000465127.1
PRRG1





TM4SF2
proline rich Gla (G-carboxyglutamic acid) 1





Uncharacterized protein; cDNA FLJ59144, highly similar to Tetraspanin-7
chr1_-_173174681 1.109 ENST00000367718.1
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr2_+_201170770 1.106 ENST00000409988.3
ENST00000409385.1
SPATS2L

spermatogenesis associated, serine-rich 2-like

chr10_-_90712520 1.097 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chr3_-_99833333 1.087 ENST00000354552.3
ENST00000331335.5
ENST00000398326.2
FILIP1L


filamin A interacting protein 1-like


chrX_+_135251783 1.084 ENST00000394153.2
FHL1
four and a half LIM domains 1
chr4_-_70361579 1.084 ENST00000512583.1
UGT2B4
UDP glucuronosyltransferase 2 family, polypeptide B4

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 11.9 GO:0016554 cytidine to uridine editing(GO:0016554)
2.4 9.4 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
2.2 6.7 GO:2000910 regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)
1.6 4.8 GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
1.3 10.5 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
1.2 1.2 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
1.2 7.0 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
1.1 10.0 GO:0031639 plasminogen activation(GO:0031639)
1.1 4.3 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.8 4.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.8 2.3 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.7 7.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.7 2.8 GO:0010716 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.7 0.7 GO:0050918 positive chemotaxis(GO:0050918)
0.7 2.0 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.6 1.9 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.6 1.8 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.6 1.8 GO:0014889 muscle atrophy(GO:0014889) regulation of skeletal muscle tissue growth(GO:0048631)
0.6 2.3 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.5 1.6 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.5 3.1 GO:0060242 contact inhibition(GO:0060242)
0.5 1.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.5 1.8 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.5 2.3 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.4 3.9 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.4 1.7 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.4 1.3 GO:1901142 insulin processing(GO:0030070) insulin metabolic process(GO:1901142)
0.4 1.9 GO:0060414 aorta development(GO:0035904) aorta morphogenesis(GO:0035909) aorta smooth muscle tissue morphogenesis(GO:0060414)
0.4 2.2 GO:0007525 somatic muscle development(GO:0007525)
0.4 1.4 GO:0060457 negative regulation of digestive system process(GO:0060457)
0.4 1.4 GO:0045218 zonula adherens maintenance(GO:0045218)
0.3 0.3 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.3 18.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.3 4.7 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.3 1.3 GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.3 4.4 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.3 2.9 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.3 1.3 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.3 0.9 GO:0003350 pulmonary myocardium development(GO:0003350)
0.3 0.9 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.3 1.2 GO:0001705 ectoderm formation(GO:0001705) central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.3 1.4 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.3 2.8 GO:0031641 regulation of myelination(GO:0031641)
0.3 0.8 GO:0070544 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188) histone H3-K36 demethylation(GO:0070544)
0.3 2.7 GO:0051014 actin filament severing(GO:0051014)
0.3 1.6 GO:0034063 stress granule assembly(GO:0034063)
0.3 0.8 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.2 3.7 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.2 1.5 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.2 0.7 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.2 2.6 GO:0006907 pinocytosis(GO:0006907)
0.2 0.9 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.2 2.6 GO:0042447 hormone catabolic process(GO:0042447)
0.2 0.2 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
0.2 2.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.2 0.6 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.2 1.8 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2 0.6 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.2 5.7 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of wound healing(GO:0061045) negative regulation of hemostasis(GO:1900047)
0.2 1.5 GO:0008354 germ cell migration(GO:0008354)
0.2 1.6 GO:0097435 extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.2 1.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.2 1.0 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.2 0.7 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.2 0.3 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.2 1.7 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.2 0.3 GO:0045750 obsolete positive regulation of S phase of mitotic cell cycle(GO:0045750)
0.2 0.5 GO:0019731 antibacterial humoral response(GO:0019731)
0.2 2.2 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.2 1.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.2 1.1 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.2 2.1 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.2 1.4 GO:0018126 protein hydroxylation(GO:0018126) tetrahydrobiopterin metabolic process(GO:0046146)
0.2 1.4 GO:0032528 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.2 0.5 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.1 0.6 GO:0071400 cellular response to oleic acid(GO:0071400)
0.1 0.6 GO:0007368 determination of left/right symmetry(GO:0007368) specification of symmetry(GO:0009799) determination of bilateral symmetry(GO:0009855)
0.1 0.6 GO:0015825 L-serine transport(GO:0015825)
0.1 0.4 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 1.7 GO:0046323 glucose import(GO:0046323)
0.1 3.1 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.1 0.6 GO:0060209 estrus(GO:0060209)
0.1 6.0 GO:0008206 bile acid metabolic process(GO:0008206)
0.1 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 0.4 GO:0060574 trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536) intestinal epithelial cell maturation(GO:0060574) intestinal epithelial cell development(GO:0060576)
0.1 9.3 GO:0055088 lipid homeostasis(GO:0055088)
0.1 0.5 GO:0000966 RNA 5'-end processing(GO:0000966)
0.1 0.9 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1 1.1 GO:0042448 progesterone metabolic process(GO:0042448)
0.1 1.5 GO:0051597 response to methylmercury(GO:0051597)
0.1 0.5 GO:0034331 cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.1 0.7 GO:0042693 muscle cell fate commitment(GO:0042693)
0.1 0.4 GO:0042416 dopamine biosynthetic process(GO:0042416)
0.1 1.1 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 1.9 GO:0008210 estrogen metabolic process(GO:0008210)
0.1 0.9 GO:0003065 regulation of heart rate by chemical signal(GO:0003062) positive regulation of heart rate by epinephrine(GO:0003065)
0.1 0.8 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 0.3 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.1 1.1 GO:0046473 phosphatidic acid metabolic process(GO:0046473)
0.1 1.9 GO:0031000 response to caffeine(GO:0031000)
0.1 0.6 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 3.0 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.1 1.5 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 37.1 GO:0006936 muscle contraction(GO:0006936)
0.1 1.1 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.1 1.0 GO:0050872 white fat cell differentiation(GO:0050872)
0.1 0.4 GO:0046621 negative regulation of organ growth(GO:0046621)
0.1 0.4 GO:0060839 lymphatic endothelial cell fate commitment(GO:0060838) endothelial cell fate commitment(GO:0060839) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.1 0.9 GO:0042594 response to starvation(GO:0042594)
0.1 0.8 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.3 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1 1.8 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.7 GO:0030644 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.1 0.2 GO:0045214 sarcomere organization(GO:0045214)
0.1 2.0 GO:0008347 glial cell migration(GO:0008347)
0.1 0.8 GO:0007567 parturition(GO:0007567)
0.1 0.7 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.1 2.5 GO:0015914 phospholipid transport(GO:0015914)
0.1 0.7 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.1 0.3 GO:0034435 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873) steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.1 0.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 5.5 GO:0051592 response to calcium ion(GO:0051592)
0.1 2.5 GO:0030325 adrenal gland development(GO:0030325)
0.1 1.7 GO:0006825 copper ion transport(GO:0006825)
0.1 0.3 GO:0009822 alkaloid catabolic process(GO:0009822)
0.1 0.2 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.1 0.6 GO:0006553 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.1 1.6 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.1 0.3 GO:0001823 ureteric bud development(GO:0001657) mesonephros development(GO:0001823) mesonephric epithelium development(GO:0072163) mesonephric tubule development(GO:0072164)
0.1 0.5 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.3 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.2 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.1 0.6 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.1 0.1 GO:0019087 transformation of host cell by virus(GO:0019087)
0.1 0.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.3 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 0.6 GO:0009249 protein lipoylation(GO:0009249)
0.1 0.3 GO:1903301 regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.1 0.2 GO:0050758 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 0.2 GO:0009820 alkaloid metabolic process(GO:0009820)
0.1 0.1 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 1.0 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.1 0.2 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 0.3 GO:0015871 choline transport(GO:0015871)
0.1 0.6 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 4.2 GO:0031668 cellular response to extracellular stimulus(GO:0031668)
0.1 5.8 GO:0051384 response to glucocorticoid(GO:0051384)
0.1 0.3 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.1 0.1 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.1 1.4 GO:0006693 prostaglandin metabolic process(GO:0006693)
0.1 0.9 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.1 0.3 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.3 GO:0032570 response to progesterone(GO:0032570)
0.1 0.2 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.1 0.1 GO:0002220 innate immune response activating cell surface receptor signaling pathway(GO:0002220)
0.1 0.2 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1 2.9 GO:0009749 response to glucose(GO:0009749)
0.1 0.2 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.2 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.1 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.1 0.2 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.2 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.3 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.1 0.7 GO:0071445 obsolete cellular response to protein stimulus(GO:0071445)
0.1 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.4 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.1 0.3 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.1 0.5 GO:0015780 nucleotide-sugar transport(GO:0015780)
0.1 4.2 GO:0008360 regulation of cell shape(GO:0008360)
0.1 0.2 GO:0042519 tyrosine phosphorylation of Stat4 protein(GO:0042504) regulation of tyrosine phosphorylation of Stat4 protein(GO:0042519) positive regulation of tyrosine phosphorylation of Stat4 protein(GO:0042520)
0.1 0.6 GO:0050687 negative regulation of defense response to virus(GO:0050687)
0.0 0.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 1.0 GO:0007045 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041)
0.0 1.8 GO:0033572 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0 0.3 GO:0046618 drug export(GO:0046618)
0.0 8.7 GO:0006979 response to oxidative stress(GO:0006979)
0.0 0.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 1.1 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 1.6 GO:0017148 negative regulation of translation(GO:0017148)
0.0 0.3 GO:0002021 response to dietary excess(GO:0002021)
0.0 1.0 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.0 GO:1900087 traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle phase transition(GO:1901989) positive regulation of mitotic cell cycle phase transition(GO:1901992) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0 0.2 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.1 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 1.4 GO:0042990 regulation of transcription factor import into nucleus(GO:0042990) transcription factor import into nucleus(GO:0042991)
0.0 0.2 GO:0001575 globoside metabolic process(GO:0001575)
0.0 0.2 GO:0000271 polysaccharide biosynthetic process(GO:0000271) glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250) cellular polysaccharide biosynthetic process(GO:0033692)
0.0 0.7 GO:0098764 meiosis I cell cycle phase(GO:0098764)
0.0 1.6 GO:0030837 negative regulation of actin filament polymerization(GO:0030837)
0.0 0.1 GO:0010896 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.2 GO:0042770 DNA damage response, signal transduction by p53 class mediator(GO:0030330) signal transduction in response to DNA damage(GO:0042770)
0.0 0.2 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 1.6 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.3 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.2 GO:0007584 response to nutrient(GO:0007584)
0.0 0.0 GO:0002921 negative regulation of humoral immune response(GO:0002921)
0.0 0.2 GO:0032754 positive regulation of interleukin-5 production(GO:0032754)
0.0 1.1 GO:0001525 angiogenesis(GO:0001525)
0.0 0.2 GO:0097061 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.6 GO:0006518 peptide metabolic process(GO:0006518)
0.0 1.3 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.0 1.1 GO:0007043 cell-cell junction assembly(GO:0007043)
0.0 0.3 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.9 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.5 GO:0016572 histone phosphorylation(GO:0016572)
0.0 1.1 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.2 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.6 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.4 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.0 0.3 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.2 GO:0009190 cyclic nucleotide biosynthetic process(GO:0009190) cyclic purine nucleotide metabolic process(GO:0052652)
0.0 0.5 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968) cellular response to unfolded protein(GO:0034620)
0.0 1.4 GO:0010038 response to metal ion(GO:0010038)
0.0 0.1 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.1 GO:0043267 negative regulation of potassium ion transport(GO:0043267) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.4 GO:0030032 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:0021984 adenohypophysis development(GO:0021984)
0.0 1.5 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 2.6 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.8 GO:0045727 positive regulation of cellular amide metabolic process(GO:0034250) positive regulation of translation(GO:0045727)
0.0 0.0 GO:0097352 autophagosome maturation(GO:0097352)
0.0 1.2 GO:0045165 cell fate commitment(GO:0045165)
0.0 0.1 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.0 GO:0010225 response to UV-C(GO:0010225)
0.0 0.4 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.0 0.7 GO:0030866 cortical cytoskeleton organization(GO:0030865) cortical actin cytoskeleton organization(GO:0030866)
0.0 0.5 GO:0006691 leukotriene metabolic process(GO:0006691)
0.0 0.1 GO:0008634 obsolete negative regulation of survival gene product expression(GO:0008634)
0.0 0.4 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.2 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.0 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.1 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.6 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.1 GO:0007204 positive regulation of cytosolic calcium ion concentration(GO:0007204)
0.0 0.2 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 2.3 GO:0006814 sodium ion transport(GO:0006814)
0.0 0.2 GO:0008272 sulfate transport(GO:0008272)
0.0 0.2 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0 1.0 GO:0051297 microtubule organizing center organization(GO:0031023) centrosome organization(GO:0051297)
0.0 0.2 GO:0015695 organic cation transport(GO:0015695)
0.0 0.4 GO:0008589 regulation of smoothened signaling pathway(GO:0008589)
0.0 0.1 GO:0007285 primary spermatocyte growth(GO:0007285)
0.0 2.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 4.7 GO:0016049 cell growth(GO:0016049)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.6 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 1.4 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.1 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.2 GO:0051924 regulation of calcium ion transport(GO:0051924)
0.0 3.9 GO:0006457 protein folding(GO:0006457)
0.0 0.8 GO:0006914 autophagy(GO:0006914)
0.0 0.0 GO:0090025 regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.3 GO:0006386 transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0 0.4 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.2 GO:0046676 negative regulation of peptide secretion(GO:0002792) negative regulation of insulin secretion(GO:0046676) negative regulation of peptide hormone secretion(GO:0090278)
0.0 0.1 GO:0045329 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0 0.2 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.5 GO:0042552 myelination(GO:0042552)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.0 GO:0051150 regulation of smooth muscle cell differentiation(GO:0051150)
0.0 0.3 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.0 GO:0090047 obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0 0.1 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.0 0.2 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.3 GO:0006953 acute-phase response(GO:0006953)
0.0 0.4 GO:0006986 response to unfolded protein(GO:0006986)
0.0 0.1 GO:0009451 RNA modification(GO:0009451)
0.0 0.0 GO:0060423 foregut regionalization(GO:0060423) lung field specification(GO:0060424) primary lung bud formation(GO:0060431) lung induction(GO:0060492) regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047) iris morphogenesis(GO:0061072)
0.0 0.2 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.0 GO:0044253 positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.0 0.1 GO:0071772 BMP signaling pathway(GO:0030509) response to BMP(GO:0071772) cellular response to BMP stimulus(GO:0071773)
0.0 0.2 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.3 GO:0035338 long-chain fatty-acyl-CoA metabolic process(GO:0035336) fatty-acyl-CoA metabolic process(GO:0035337) long-chain fatty-acyl-CoA biosynthetic process(GO:0035338) fatty-acyl-CoA biosynthetic process(GO:0046949)
0.0 0.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.2 GO:0007566 embryo implantation(GO:0007566)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.3 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.2 GO:0007286 spermatid development(GO:0007286)
0.0 0.1 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.2 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 1.3 GO:0007507 heart development(GO:0007507)
0.0 0.6 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.0 GO:0009629 response to gravity(GO:0009629)
0.0 0.0 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 11.9 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
1.6 9.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) beta-catenin-TCF complex(GO:1990907)
0.8 17.6 GO:0042627 chylomicron(GO:0042627)
0.6 2.8 GO:0071438 invadopodium membrane(GO:0071438)
0.6 7.7 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.5 3.2 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.5 1.6 GO:0005588 collagen type V trimer(GO:0005588)
0.5 3.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.5 1.8 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.4 4.9 GO:0005577 fibrinogen complex(GO:0005577)
0.4 3.0 GO:0042788 polysomal ribosome(GO:0042788)
0.4 1.5 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.4 1.4 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.3 1.4 GO:0005915 zonula adherens(GO:0005915)
0.3 2.5 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.2 2.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 1.7 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.2 1.4 GO:0045179 apical cortex(GO:0045179)
0.2 3.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 1.9 GO:0005579 membrane attack complex(GO:0005579)
0.2 1.5 GO:1990752 microtubule plus-end(GO:0035371) microtubule end(GO:1990752)
0.2 1.5 GO:0016589 NURF complex(GO:0016589)
0.2 42.7 GO:0005925 focal adhesion(GO:0005925)
0.2 1.0 GO:0016342 catenin complex(GO:0016342)
0.2 1.2 GO:0042587 glycogen granule(GO:0042587)
0.1 0.7 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 6.0 GO:0030018 Z disc(GO:0030018)
0.1 0.6 GO:0043219 lateral loop(GO:0043219)
0.1 9.8 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 3.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.5 GO:0031674 I band(GO:0031674)
0.1 0.9 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 1.0 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 0.3 GO:0005916 fascia adherens(GO:0005916)
0.1 2.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.4 GO:0071437 invadopodium(GO:0071437)
0.1 0.3 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.3 GO:0005873 plus-end kinesin complex(GO:0005873)
0.1 1.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 1.1 GO:0030673 axolemma(GO:0030673)
0.1 2.0 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.6 GO:0033268 node of Ranvier(GO:0033268)
0.1 7.1 GO:0016459 myosin complex(GO:0016459)
0.1 6.4 GO:0030017 sarcomere(GO:0030017)
0.1 1.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.3 GO:0071546 pi-body(GO:0071546)
0.1 1.9 GO:0030057 desmosome(GO:0030057)
0.1 1.0 GO:0008091 spectrin(GO:0008091)
0.1 1.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.6 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1 1.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 3.3 GO:0070161 adherens junction(GO:0005912) anchoring junction(GO:0070161)
0.1 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.3 GO:0031310 intrinsic component of endosome membrane(GO:0031302) intrinsic component of vacuolar membrane(GO:0031310) Weibel-Palade body(GO:0033093)
0.1 0.5 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.1 1.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 0.6 GO:0032420 stereocilium(GO:0032420)
0.1 0.9 GO:0005871 kinesin complex(GO:0005871)
0.1 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.6 GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1 2.2 GO:0043204 perikaryon(GO:0043204)
0.1 0.8 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.9 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 4.4 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 1.9 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 3.6 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.6 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 35.0 GO:0005615 extracellular space(GO:0005615)
0.0 10.8 GO:0005792 obsolete microsome(GO:0005792)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 6.3 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 0.5 GO:0001527 microfibril(GO:0001527)
0.0 36.0 GO:0005576 extracellular region(GO:0005576)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:0005771 multivesicular body(GO:0005771)
0.0 0.3 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.7 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.4 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.4 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 2.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 11.3 GO:0005815 microtubule organizing center(GO:0005815)
0.0 0.3 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119) clathrin adaptor complex(GO:0030131)
0.0 0.1 GO:0005712 chiasma(GO:0005712) MutLbeta complex(GO:0032390)
0.0 0.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0016012 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.7 GO:0031526 brush border membrane(GO:0031526)
0.0 0.8 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.1 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.0 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032) PAS complex(GO:0070772)
0.0 1.7 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.1 GO:0005581 collagen trimer(GO:0005581)
0.0 5.9 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 0.1 GO:0000806 Y chromosome(GO:0000806)
0.0 2.5 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 0.2 GO:0000299 obsolete integral to membrane of membrane fraction(GO:0000299)
0.0 0.7 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.2 GO:0031201 SNARE complex(GO:0031201)
0.0 0.3 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.8 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.3 GO:0009986 cell surface(GO:0009986)
0.0 0.2 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.4 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.1 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.1 GO:0044449 contractile fiber part(GO:0044449)
0.0 0.3 GO:0016234 inclusion body(GO:0016234)
0.0 0.1 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.1 GO:0005625 obsolete soluble fraction(GO:0005625)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.2 GO:0019958 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
2.2 10.9 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
2.0 8.0 GO:0034190 apolipoprotein receptor binding(GO:0034190) high-density lipoprotein particle receptor binding(GO:0070653)
1.5 13.9 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.9 3.8 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.9 27.7 GO:0005523 tropomyosin binding(GO:0005523)
0.6 2.6 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.6 15.6 GO:0008430 selenium binding(GO:0008430)
0.6 9.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.6 1.8 GO:0047718 indanol dehydrogenase activity(GO:0047718)
0.6 2.3 GO:0016841 ammonia-lyase activity(GO:0016841)
0.5 1.0 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.5 2.4 GO:0004064 arylesterase activity(GO:0004064)
0.5 1.9 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.5 2.9 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.5 1.9 GO:0008184 purine nucleobase binding(GO:0002060) glycogen phosphorylase activity(GO:0008184)
0.5 1.4 GO:0050692 DBD domain binding(GO:0050692)
0.5 5.0 GO:0015643 toxic substance binding(GO:0015643)
0.4 1.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.4 1.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.4 2.9 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.4 0.8 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.4 1.6 GO:0019862 IgA binding(GO:0019862)
0.4 1.2 GO:0047708 biotinidase activity(GO:0047708)
0.4 1.9 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.4 3.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.4 1.5 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.4 8.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.4 1.4 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.4 2.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.4 3.6 GO:0017049 GTP-Rho binding(GO:0017049)
0.4 1.8 GO:0003680 AT DNA binding(GO:0003680)
0.3 1.4 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.3 1.7 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.3 1.3 GO:0004180 carboxypeptidase activity(GO:0004180)
0.3 1.3 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.3 4.8 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.3 1.3 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.3 4.1 GO:0004065 arylsulfatase activity(GO:0004065)
0.3 1.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.3 1.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.3 0.8 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.3 11.0 GO:0003725 double-stranded RNA binding(GO:0003725)
0.2 5.4 GO:0043499 obsolete eukaryotic cell surface binding(GO:0043499)
0.2 2.2 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.2 1.5 GO:0042577 lipid phosphatase activity(GO:0042577)
0.2 1.2 GO:0034235 GPI anchor binding(GO:0034235)
0.2 1.6 GO:0030492 hemoglobin binding(GO:0030492)
0.2 2.8 GO:0045295 gamma-catenin binding(GO:0045295)
0.2 1.0 GO:0031708 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.2 1.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.2 1.8 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 0.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.2 19.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 0.6 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.2 5.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 1.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 0.9 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 7.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 1.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 0.8 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.2 1.6 GO:0008199 ferric iron binding(GO:0008199)
0.2 2.9 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 1.0 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.2 1.1 GO:0042731 PH domain binding(GO:0042731)
0.2 0.3 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.2 2.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 3.0 GO:0070064 proline-rich region binding(GO:0070064)
0.1 1.6 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.1 1.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.0 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 1.5 GO:0031491 nucleosome binding(GO:0031491)
0.1 0.6 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.4 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 1.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.7 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 0.8 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 1.8 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 4.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.8 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 1.6 GO:0043274 phospholipase binding(GO:0043274)
0.1 2.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.4 GO:0050051 leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.1 0.9 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 0.7 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 5.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 4.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.9 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 14.3 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.1 1.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.3 GO:0034584 piRNA binding(GO:0034584)
0.1 0.5 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.3 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.1 2.0 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 0.6 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 0.6 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 1.7 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 0.2 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 0.2 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.1 0.4 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.1 0.7 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.3 GO:0010698 angiotensin type I receptor activity(GO:0001596) acetyltransferase activator activity(GO:0010698)
0.1 0.3 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.1 0.7 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 1.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 0.2 GO:0030151 molybdenum ion binding(GO:0030151)
0.1 2.8 GO:0051219 phosphoprotein binding(GO:0051219)
0.1 0.9 GO:0017127 cholesterol transporter activity(GO:0017127)
0.1 1.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 0.7 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 1.2 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.1 0.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510) bicarbonate transmembrane transporter activity(GO:0015106)
0.1 0.4 GO:0033989 long-chain-enoyl-CoA hydratase activity(GO:0016508) 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989)
0.1 0.3 GO:0009922 fatty acid elongase activity(GO:0009922)
0.1 0.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.6 GO:0016595 glutamate binding(GO:0016595)
0.1 0.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 0.6 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 0.9 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.6 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.1 0.6 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.8 GO:0090079 translation regulator activity, nucleic acid binding(GO:0090079)
0.1 0.4 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.6 GO:0042805 actinin binding(GO:0042805)
0.1 0.8 GO:0070411 I-SMAD binding(GO:0070411)
0.1 1.7 GO:0030552 cAMP binding(GO:0030552)
0.1 0.9 GO:0017166 vinculin binding(GO:0017166)
0.1 0.2 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 0.8 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.1 0.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.3 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 1.1 GO:0070330 aromatase activity(GO:0070330)
0.1 0.8 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 0.2 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.1 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.1 0.4 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 1.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0008148 obsolete negative transcription elongation factor activity(GO:0008148)
0.0 0.1 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.0 1.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.5 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 4.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.3 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.6 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.3 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 7.1 GO:0003774 motor activity(GO:0003774)
0.0 3.8 GO:0008201 heparin binding(GO:0008201)
0.0 0.2 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.5 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.4 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.9 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465) acyloxyacyl hydrolase activity(GO:0050528)
0.0 2.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 2.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 2.2 GO:0042562 hormone binding(GO:0042562)
0.0 1.7 GO:0005507 copper ion binding(GO:0005507)
0.0 1.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.7 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.3 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 5.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.7 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.1 GO:0051636 obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0 1.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.1 GO:0016847 1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0 0.6 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 1.4 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0004428 obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
0.0 0.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.8 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.2 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 0.0 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.2 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.6 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.7 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 4.6 GO:0030528 obsolete transcription regulator activity(GO:0030528)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.3 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.5 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 2.1 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.5 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0034979 NAD-dependent protein deacetylase activity(GO:0034979)
0.0 0.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.2 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.1 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.0 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.1 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.5 GO:0051287 NAD binding(GO:0051287)
0.0 0.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.2 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.8 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.1 GO:0016615 malate dehydrogenase activity(GO:0016615)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.2 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 3.3 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.7 ST_ADRENERGIC Adrenergic Pathway
0.0 1.1 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.6 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.4 SIG_CHEMOTAXIS Genes related to chemotaxis
0.0 0.5 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.1 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.0 0.5 ST_GA12_PATHWAY G alpha 12 Pathway