Motif ID: FOXO3_FOXD2
Z-value: 1.827
Transcription factors associated with FOXO3_FOXD2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
FOXD2 | ENSG00000186564.5 | FOXD2 |
FOXO3 | ENSG00000118689.10 | FOXO3 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 4.7 | GO:0060649 | nipple development(GO:0060618) mammary gland bud elongation(GO:0060649) nipple morphogenesis(GO:0060658) nipple sheath formation(GO:0060659) |
1.0 | 1.0 | GO:0003006 | developmental process involved in reproduction(GO:0003006) |
0.8 | 2.5 | GO:1901724 | positive regulation of cell proliferation involved in kidney development(GO:1901724) |
0.7 | 2.6 | GO:0031580 | membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) |
0.6 | 1.9 | GO:0045603 | positive regulation of endothelial cell differentiation(GO:0045603) |
0.6 | 2.5 | GO:0010157 | response to chlorate(GO:0010157) |
0.6 | 1.8 | GO:0035461 | vitamin transmembrane transport(GO:0035461) |
0.4 | 1.3 | GO:0071603 | negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) endothelial cell-cell adhesion(GO:0071603) |
0.4 | 2.5 | GO:0006196 | AMP catabolic process(GO:0006196) |
0.4 | 1.7 | GO:0042320 | regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) |
0.4 | 1.2 | GO:0010430 | ethanol catabolic process(GO:0006068) fatty acid omega-oxidation(GO:0010430) |
0.4 | 1.6 | GO:0051573 | negative regulation of histone H3-K9 methylation(GO:0051573) |
0.4 | 1.2 | GO:0002035 | brain renin-angiotensin system(GO:0002035) |
0.4 | 2.4 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) |
0.4 | 0.4 | GO:0034310 | primary alcohol catabolic process(GO:0034310) |
0.4 | 1.4 | GO:0045338 | farnesyl diphosphate metabolic process(GO:0045338) |
0.4 | 1.4 | GO:0019805 | quinolinate biosynthetic process(GO:0019805) |
0.4 | 1.8 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
0.3 | 1.4 | GO:0021759 | globus pallidus development(GO:0021759) menarche(GO:0042696) |
0.3 | 1.3 | GO:0002318 | myeloid progenitor cell differentiation(GO:0002318) |
0.3 | 0.9 | GO:0002291 | T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291) |
0.3 | 1.2 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
0.3 | 1.2 | GO:0045085 | negative regulation of interleukin-2 biosynthetic process(GO:0045085) |
0.3 | 2.6 | GO:1900087 | traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808) |
0.3 | 0.9 | GO:0014900 | smooth muscle hyperplasia(GO:0014806) muscle hyperplasia(GO:0014900) positive regulation of guanylate cyclase activity(GO:0031284) |
0.3 | 1.8 | GO:0061029 | eyelid development in camera-type eye(GO:0061029) |
0.3 | 0.8 | GO:2000078 | epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287) regulation of type B pancreatic cell development(GO:2000074) positive regulation of type B pancreatic cell development(GO:2000078) |
0.3 | 1.5 | GO:0006883 | cellular sodium ion homeostasis(GO:0006883) |
0.2 | 0.7 | GO:0001780 | neutrophil homeostasis(GO:0001780) |
0.2 | 0.7 | GO:0060120 | auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120) |
0.2 | 1.4 | GO:0031665 | negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665) |
0.2 | 10.4 | GO:0002286 | T cell activation involved in immune response(GO:0002286) |
0.2 | 4.1 | GO:0016601 | Rac protein signal transduction(GO:0016601) |
0.2 | 1.1 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
0.2 | 3.5 | GO:0007020 | microtubule nucleation(GO:0007020) |
0.2 | 0.7 | GO:0072203 | kidney mesenchymal cell proliferation(GO:0072135) metanephric mesenchymal cell proliferation involved in metanephros development(GO:0072136) cell proliferation involved in metanephros development(GO:0072203) |
0.2 | 1.7 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
0.2 | 0.9 | GO:0043922 | negative regulation by host of viral transcription(GO:0043922) |
0.2 | 0.9 | GO:0070527 | integrin activation(GO:0033622) regulation of integrin activation(GO:0033623) positive regulation of integrin activation(GO:0033625) platelet aggregation(GO:0070527) |
0.2 | 0.4 | GO:0045074 | negative regulation of interleukin-10 production(GO:0032693) interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074) |
0.2 | 1.0 | GO:0017055 | negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) |
0.2 | 0.6 | GO:0045759 | negative regulation of action potential(GO:0045759) |
0.2 | 0.6 | GO:0048852 | diencephalon morphogenesis(GO:0048852) |
0.2 | 0.8 | GO:0032817 | regulation of natural killer cell proliferation(GO:0032817) |
0.2 | 2.1 | GO:0001706 | endoderm formation(GO:0001706) |
0.2 | 0.6 | GO:0046521 | sphingoid catabolic process(GO:0046521) |
0.2 | 0.5 | GO:0070171 | negative regulation of histone methylation(GO:0031061) negative regulation of tooth mineralization(GO:0070171) |
0.2 | 0.3 | GO:0008050 | female courtship behavior(GO:0008050) |
0.2 | 3.5 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
0.2 | 0.6 | GO:1904037 | positive regulation of epithelial cell apoptotic process(GO:1904037) positive regulation of endothelial cell apoptotic process(GO:2000353) |
0.2 | 2.2 | GO:0045070 | positive regulation of viral genome replication(GO:0045070) |
0.2 | 0.6 | GO:0046022 | regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022) |
0.2 | 0.8 | GO:0071542 | dopaminergic neuron differentiation(GO:0071542) |
0.2 | 0.8 | GO:0010508 | positive regulation of autophagy(GO:0010508) |
0.2 | 1.2 | GO:0042149 | cellular response to glucose starvation(GO:0042149) |
0.1 | 0.9 | GO:0032825 | regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825) |
0.1 | 1.0 | GO:0015671 | oxygen transport(GO:0015671) |
0.1 | 0.4 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
0.1 | 5.4 | GO:0006271 | DNA strand elongation involved in DNA replication(GO:0006271) |
0.1 | 0.4 | GO:0031034 | skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688) |
0.1 | 0.4 | GO:0007518 | myoblast fate determination(GO:0007518) |
0.1 | 2.5 | GO:1904031 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031) |
0.1 | 3.7 | GO:0033209 | tumor necrosis factor-mediated signaling pathway(GO:0033209) |
0.1 | 0.5 | GO:0030259 | lipid glycosylation(GO:0030259) |
0.1 | 0.4 | GO:0006288 | base-excision repair, DNA ligation(GO:0006288) |
0.1 | 0.3 | GO:0050862 | positive regulation of T cell receptor signaling pathway(GO:0050862) |
0.1 | 0.4 | GO:1904396 | regulation of synaptic growth at neuromuscular junction(GO:0008582) regulation of neuromuscular junction development(GO:1904396) |
0.1 | 0.4 | GO:0035623 | renal glucose absorption(GO:0035623) |
0.1 | 0.5 | GO:0045589 | regulation of regulatory T cell differentiation(GO:0045589) |
0.1 | 2.1 | GO:0006906 | vesicle fusion(GO:0006906) |
0.1 | 0.5 | GO:0002052 | positive regulation of neuroblast proliferation(GO:0002052) |
0.1 | 2.0 | GO:0050930 | induction of positive chemotaxis(GO:0050930) |
0.1 | 0.6 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
0.1 | 0.6 | GO:0018106 | peptidyl-histidine phosphorylation(GO:0018106) |
0.1 | 0.1 | GO:0032656 | interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656) negative regulation of interleukin-13 production(GO:0032696) negative regulation of interleukin-5 production(GO:0032714) |
0.1 | 0.4 | GO:0006391 | transcription initiation from mitochondrial promoter(GO:0006391) |
0.1 | 0.4 | GO:0071353 | cellular response to interleukin-4(GO:0071353) |
0.1 | 0.7 | GO:0048853 | forebrain morphogenesis(GO:0048853) |
0.1 | 0.2 | GO:0051151 | negative regulation of smooth muscle cell differentiation(GO:0051151) |
0.1 | 0.3 | GO:0071104 | response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105) |
0.1 | 1.3 | GO:0032876 | regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023) |
0.1 | 0.3 | GO:0060267 | transformation of host cell by virus(GO:0019087) positive regulation of respiratory burst(GO:0060267) |
0.1 | 0.7 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
0.1 | 0.3 | GO:0048865 | stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867) |
0.1 | 0.8 | GO:0048535 | positive regulation of interleukin-12 biosynthetic process(GO:0045084) lymph node development(GO:0048535) |
0.1 | 0.3 | GO:0032416 | negative regulation of sodium:proton antiporter activity(GO:0032416) positive regulation of dopamine receptor signaling pathway(GO:0060161) negative regulation of sodium ion transmembrane transport(GO:1902306) negative regulation of sodium ion transmembrane transporter activity(GO:2000650) |
0.1 | 1.0 | GO:0006975 | DNA damage induced protein phosphorylation(GO:0006975) |
0.1 | 0.4 | GO:0046621 | negative regulation of organ growth(GO:0046621) |
0.1 | 1.6 | GO:0045730 | respiratory burst(GO:0045730) |
0.1 | 0.3 | GO:0006542 | glutamine biosynthetic process(GO:0006542) |
0.1 | 1.6 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
0.1 | 0.3 | GO:0019056 | modulation by virus of host transcription(GO:0019056) regulation of sprouting of injured axon(GO:0048686) positive regulation of sprouting of injured axon(GO:0048687) regulation of axon extension involved in regeneration(GO:0048690) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026) |
0.1 | 0.3 | GO:0040034 | regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505) |
0.1 | 1.3 | GO:0008625 | extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191) |
0.1 | 3.9 | GO:0070374 | positive regulation of ERK1 and ERK2 cascade(GO:0070374) |
0.1 | 0.3 | GO:0006531 | aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533) |
0.1 | 0.5 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672) |
0.1 | 0.9 | GO:0048585 | negative regulation of response to stimulus(GO:0048585) |
0.1 | 2.0 | GO:0000291 | nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
0.1 | 1.4 | GO:0006959 | humoral immune response(GO:0006959) |
0.1 | 0.2 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
0.1 | 1.1 | GO:0030889 | negative regulation of B cell proliferation(GO:0030889) |
0.1 | 0.7 | GO:0001932 | regulation of protein phosphorylation(GO:0001932) |
0.1 | 4.8 | GO:0030183 | B cell differentiation(GO:0030183) |
0.1 | 0.4 | GO:0071168 | protein localization to chromatin(GO:0071168) |
0.1 | 0.7 | GO:0032464 | positive regulation of protein homooligomerization(GO:0032464) |
0.1 | 0.7 | GO:0045779 | negative regulation of bone resorption(GO:0045779) |
0.1 | 1.2 | GO:0030260 | entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828) |
0.1 | 0.4 | GO:0045722 | positive regulation of gluconeogenesis(GO:0045722) |
0.1 | 1.8 | GO:0006309 | DNA catabolic process, endonucleolytic(GO:0000737) apoptotic DNA fragmentation(GO:0006309) |
0.1 | 0.4 | GO:0055009 | atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009) |
0.1 | 0.6 | GO:0043497 | regulation of protein heterodimerization activity(GO:0043497) |
0.1 | 1.6 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
0.1 | 0.7 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
0.1 | 6.0 | GO:0031295 | lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295) |
0.1 | 0.3 | GO:0010447 | response to acidic pH(GO:0010447) |
0.1 | 1.1 | GO:0042730 | fibrinolysis(GO:0042730) |
0.1 | 0.7 | GO:0007494 | midgut development(GO:0007494) |
0.1 | 0.2 | GO:0043276 | anoikis(GO:0043276) |
0.1 | 0.5 | GO:0050912 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) detection of chemical stimulus involved in sensory perception of taste(GO:0050912) |
0.1 | 0.6 | GO:0045616 | regulation of keratinocyte differentiation(GO:0045616) |
0.1 | 0.3 | GO:0043568 | positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568) |
0.1 | 0.9 | GO:0034440 | fatty acid oxidation(GO:0019395) lipid oxidation(GO:0034440) |
0.1 | 0.5 | GO:0042572 | retinol metabolic process(GO:0042572) |
0.1 | 0.9 | GO:0032720 | negative regulation of tumor necrosis factor production(GO:0032720) negative regulation of tumor necrosis factor superfamily cytokine production(GO:1903556) |
0.1 | 0.7 | GO:0001893 | maternal placenta development(GO:0001893) |
0.1 | 0.5 | GO:0007141 | male meiosis I(GO:0007141) |
0.1 | 1.8 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.1 | 0.7 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
0.1 | 0.9 | GO:0034605 | cellular response to heat(GO:0034605) |
0.1 | 2.6 | GO:0043484 | regulation of RNA splicing(GO:0043484) |
0.0 | 0.7 | GO:0043330 | response to exogenous dsRNA(GO:0043330) |
0.0 | 0.3 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) |
0.0 | 0.2 | GO:0030037 | actin filament reorganization involved in cell cycle(GO:0030037) actin filament reorganization(GO:0090527) |
0.0 | 0.3 | GO:0001660 | fever generation(GO:0001660) |
0.0 | 0.2 | GO:0032959 | inositol trisphosphate biosynthetic process(GO:0032959) |
0.0 | 1.0 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
0.0 | 0.1 | GO:0042074 | cell migration involved in gastrulation(GO:0042074) |
0.0 | 2.4 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
0.0 | 0.3 | GO:0090151 | establishment of protein localization to mitochondrial membrane(GO:0090151) |
0.0 | 0.3 | GO:0044245 | polysaccharide digestion(GO:0044245) |
0.0 | 0.1 | GO:2000831 | renin-angiotensin regulation of aldosterone production(GO:0002018) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) positive regulation of NAD(P)H oxidase activity(GO:0033864) corticosteroid hormone secretion(GO:0035930) mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846) regulation of mineralocorticoid secretion(GO:2000855) regulation of aldosterone secretion(GO:2000858) |
0.0 | 0.3 | GO:0016098 | monoterpenoid metabolic process(GO:0016098) |
0.0 | 0.2 | GO:0070071 | response to fructose(GO:0009750) proton-transporting two-sector ATPase complex assembly(GO:0070071) |
0.0 | 0.2 | GO:0070254 | mucus secretion(GO:0070254) |
0.0 | 0.8 | GO:0051353 | positive regulation of oxidoreductase activity(GO:0051353) |
0.0 | 0.2 | GO:0007416 | synapse assembly(GO:0007416) |
0.0 | 1.0 | GO:0006783 | heme biosynthetic process(GO:0006783) |
0.0 | 0.2 | GO:0008228 | opsonization(GO:0008228) |
0.0 | 0.5 | GO:0019228 | neuronal action potential(GO:0019228) |
0.0 | 1.9 | GO:0007193 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193) |
0.0 | 0.0 | GO:0060684 | epithelial-mesenchymal cell signaling(GO:0060684) |
0.0 | 0.5 | GO:0033138 | positive regulation of peptidyl-serine phosphorylation(GO:0033138) |
0.0 | 0.7 | GO:0042102 | positive regulation of T cell proliferation(GO:0042102) |
0.0 | 0.4 | GO:0032438 | melanosome organization(GO:0032438) pigment granule organization(GO:0048753) |
0.0 | 0.1 | GO:0051823 | regulation of synapse structural plasticity(GO:0051823) |
0.0 | 2.9 | GO:0007163 | establishment or maintenance of cell polarity(GO:0007163) |
0.0 | 0.8 | GO:0050870 | positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039) |
0.0 | 2.8 | GO:0097696 | JAK-STAT cascade(GO:0007259) STAT cascade(GO:0097696) |
0.0 | 0.3 | GO:0060042 | retina morphogenesis in camera-type eye(GO:0060042) |
0.0 | 0.2 | GO:0006422 | aspartyl-tRNA aminoacylation(GO:0006422) |
0.0 | 0.2 | GO:0042797 | 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797) |
0.0 | 0.1 | GO:0046618 | drug export(GO:0046618) |
0.0 | 1.2 | GO:0000725 | double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725) |
0.0 | 0.3 | GO:0043537 | negative regulation of blood vessel endothelial cell migration(GO:0043537) |
0.0 | 0.1 | GO:0002541 | activation of plasma proteins involved in acute inflammatory response(GO:0002541) |
0.0 | 0.7 | GO:0015701 | bicarbonate transport(GO:0015701) |
0.0 | 0.2 | GO:0007258 | JUN phosphorylation(GO:0007258) |
0.0 | 0.1 | GO:0071425 | hematopoietic stem cell proliferation(GO:0071425) |
0.0 | 0.2 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
0.0 | 0.4 | GO:0001503 | ossification(GO:0001503) |
0.0 | 0.1 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
0.0 | 0.3 | GO:0060644 | mammary gland epithelial cell differentiation(GO:0060644) |
0.0 | 0.9 | GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771) |
0.0 | 1.7 | GO:0006968 | cellular defense response(GO:0006968) |
0.0 | 0.4 | GO:0051966 | regulation of synaptic transmission, glutamatergic(GO:0051966) |
0.0 | 0.0 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
0.0 | 0.6 | GO:0050806 | positive regulation of synaptic transmission(GO:0050806) |
0.0 | 0.2 | GO:0016045 | detection of bacterium(GO:0016045) |
0.0 | 0.4 | GO:0046777 | protein autophosphorylation(GO:0046777) |
0.0 | 0.2 | GO:0016576 | histone dephosphorylation(GO:0016576) |
0.0 | 0.4 | GO:0071300 | cellular response to retinoic acid(GO:0071300) |
0.0 | 2.2 | GO:0007204 | positive regulation of cytosolic calcium ion concentration(GO:0007204) |
0.0 | 0.5 | GO:0045907 | positive regulation of vasoconstriction(GO:0045907) |
0.0 | 4.5 | GO:0006470 | protein dephosphorylation(GO:0006470) |
0.0 | 0.2 | GO:0016180 | snRNA processing(GO:0016180) |
0.0 | 0.3 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
0.0 | 0.5 | GO:0007528 | neuromuscular junction development(GO:0007528) |
0.0 | 0.8 | GO:0000080 | mitotic G1 phase(GO:0000080) |
0.0 | 0.2 | GO:0030262 | apoptotic nuclear changes(GO:0030262) |
0.0 | 0.8 | GO:0006730 | one-carbon metabolic process(GO:0006730) |
0.0 | 0.7 | GO:0007045 | cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) |
0.0 | 1.0 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
0.0 | 0.1 | GO:0043650 | glutamate biosynthetic process(GO:0006537) glutamate catabolic process(GO:0006538) dicarboxylic acid biosynthetic process(GO:0043650) |
0.0 | 0.8 | GO:0000186 | activation of MAPKK activity(GO:0000186) |
0.0 | 0.4 | GO:0007219 | Notch signaling pathway(GO:0007219) |
0.0 | 0.0 | GO:0048840 | otolith development(GO:0048840) |
0.0 | 0.2 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
0.0 | 0.1 | GO:0051001 | negative regulation of nitric-oxide synthase activity(GO:0051001) |
0.0 | 0.1 | GO:0006642 | triglyceride mobilization(GO:0006642) |
0.0 | 0.4 | GO:0019098 | mating behavior(GO:0007617) reproductive behavior(GO:0019098) multi-organism reproductive behavior(GO:0044705) |
0.0 | 1.7 | GO:0007605 | sensory perception of sound(GO:0007605) |
0.0 | 1.6 | GO:0008277 | regulation of G-protein coupled receptor protein signaling pathway(GO:0008277) |
0.0 | 0.8 | GO:0019233 | sensory perception of pain(GO:0019233) |
0.0 | 0.1 | GO:0046520 | diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520) |
0.0 | 0.2 | GO:0001754 | eye photoreceptor cell differentiation(GO:0001754) eye photoreceptor cell development(GO:0042462) |
0.0 | 0.2 | GO:0021680 | cerebellar Purkinje cell layer development(GO:0021680) |
0.0 | 0.6 | GO:0016445 | somatic diversification of immunoglobulins(GO:0016445) |
0.0 | 0.2 | GO:0021549 | cerebellum development(GO:0021549) |
0.0 | 0.2 | GO:0033189 | response to vitamin A(GO:0033189) |
0.0 | 0.0 | GO:0045672 | positive regulation of osteoclast differentiation(GO:0045672) |
0.0 | 0.5 | GO:0006611 | protein export from nucleus(GO:0006611) |
0.0 | 0.5 | GO:0001892 | embryonic placenta development(GO:0001892) |
0.0 | 0.6 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
0.0 | 0.2 | GO:0098657 | neurotransmitter uptake(GO:0001504) import into cell(GO:0098657) |
0.0 | 0.1 | GO:0007635 | chemosensory behavior(GO:0007635) |
0.0 | 1.0 | GO:0006821 | chloride transport(GO:0006821) |
0.0 | 0.2 | GO:0008206 | bile acid metabolic process(GO:0008206) |
0.0 | 1.8 | GO:0045333 | cellular respiration(GO:0045333) |
0.0 | 0.6 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
0.0 | 0.1 | GO:0001960 | negative regulation of cytokine-mediated signaling pathway(GO:0001960) |
0.0 | 0.2 | GO:0007032 | endosome organization(GO:0007032) |
0.0 | 0.8 | GO:0061025 | membrane fusion(GO:0061025) |
0.0 | 0.3 | GO:0070830 | bicellular tight junction assembly(GO:0070830) |
0.0 | 0.2 | GO:0031293 | membrane protein intracellular domain proteolysis(GO:0031293) |
0.0 | 0.5 | GO:1901342 | regulation of angiogenesis(GO:0045765) regulation of vasculature development(GO:1901342) |
0.0 | 0.2 | GO:0001501 | skeletal system development(GO:0001501) |
0.0 | 0.2 | GO:0015695 | organic cation transport(GO:0015695) |
0.0 | 1.5 | GO:0007565 | female pregnancy(GO:0007565) |
0.0 | 0.5 | GO:0042593 | carbohydrate homeostasis(GO:0033500) glucose homeostasis(GO:0042593) |
0.0 | 1.3 | GO:0008654 | phospholipid biosynthetic process(GO:0008654) |
0.0 | 0.2 | GO:0006596 | polyamine biosynthetic process(GO:0006596) |
0.0 | 1.3 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
0.0 | 0.9 | GO:0006338 | chromatin remodeling(GO:0006338) |
0.0 | 0.6 | GO:0050852 | T cell receptor signaling pathway(GO:0050852) |
0.0 | 0.1 | GO:0030382 | sperm mitochondrion organization(GO:0030382) |
0.0 | 0.6 | GO:0030216 | keratinocyte differentiation(GO:0030216) |
0.0 | 0.2 | GO:0000768 | syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520) |
0.0 | 0.2 | GO:0051865 | protein autoubiquitination(GO:0051865) |
0.0 | 0.7 | GO:0016579 | protein deubiquitination(GO:0016579) |
0.0 | 0.5 | GO:0016064 | immunoglobulin mediated immune response(GO:0016064) |
0.0 | 0.0 | GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886) |
0.0 | 0.1 | GO:0007212 | dopamine receptor signaling pathway(GO:0007212) |
0.0 | 0.2 | GO:0006000 | fructose metabolic process(GO:0006000) |
0.0 | 1.5 | GO:0007268 | chemical synaptic transmission(GO:0007268) anterograde trans-synaptic signaling(GO:0098916) trans-synaptic signaling(GO:0099537) |
0.0 | 0.2 | GO:0006098 | pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682) |
0.0 | 0.2 | GO:0030514 | negative regulation of BMP signaling pathway(GO:0030514) |
0.0 | 0.3 | GO:0006469 | negative regulation of protein kinase activity(GO:0006469) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 9.2 | GO:0001891 | phagocytic cup(GO:0001891) |
0.4 | 5.4 | GO:0042555 | MCM complex(GO:0042555) |
0.4 | 3.5 | GO:0005828 | kinetochore microtubule(GO:0005828) |
0.2 | 1.7 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
0.2 | 0.6 | GO:0005863 | striated muscle myosin thick filament(GO:0005863) |
0.2 | 1.4 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.1 | 1.6 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
0.1 | 0.4 | GO:0042629 | mast cell granule(GO:0042629) |
0.1 | 0.5 | GO:0032585 | multivesicular body membrane(GO:0032585) |
0.1 | 4.8 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.1 | 1.4 | GO:0030990 | intraciliary transport particle(GO:0030990) |
0.1 | 0.9 | GO:0031304 | intrinsic component of mitochondrial inner membrane(GO:0031304) |
0.1 | 0.7 | GO:0000445 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
0.1 | 9.5 | GO:0016363 | nuclear matrix(GO:0016363) |
0.1 | 1.0 | GO:0016442 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
0.1 | 0.4 | GO:0005688 | U6 snRNP(GO:0005688) |
0.1 | 0.7 | GO:0000796 | condensin complex(GO:0000796) |
0.1 | 1.0 | GO:0005833 | hemoglobin complex(GO:0005833) |
0.1 | 2.6 | GO:0034704 | calcium channel complex(GO:0034704) |
0.1 | 2.0 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.1 | 0.3 | GO:0005899 | insulin receptor complex(GO:0005899) |
0.1 | 0.4 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
0.1 | 0.3 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
0.1 | 0.4 | GO:0008278 | cohesin complex(GO:0008278) |
0.0 | 1.7 | GO:0031526 | brush border membrane(GO:0031526) |
0.0 | 1.3 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.0 | 2.6 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.0 | 3.2 | GO:0016020 | membrane(GO:0016020) |
0.0 | 1.6 | GO:0030530 | obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530) |
0.0 | 0.2 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453) |
0.0 | 0.7 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
0.0 | 0.6 | GO:0005903 | brush border(GO:0005903) |
0.0 | 0.9 | GO:0001772 | immunological synapse(GO:0001772) |
0.0 | 0.7 | GO:0042613 | MHC class II protein complex(GO:0042613) |
0.0 | 1.3 | GO:0045095 | keratin filament(GO:0045095) |
0.0 | 0.2 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
0.0 | 0.6 | GO:0030867 | rough endoplasmic reticulum membrane(GO:0030867) |
0.0 | 5.7 | GO:0005769 | early endosome(GO:0005769) |
0.0 | 1.0 | GO:0005871 | kinesin complex(GO:0005871) |
0.0 | 0.8 | GO:0005626 | obsolete insoluble fraction(GO:0005626) |
0.0 | 1.2 | GO:0005902 | microvillus(GO:0005902) |
0.0 | 0.8 | GO:0005801 | cis-Golgi network(GO:0005801) |
0.0 | 0.5 | GO:0032982 | myosin filament(GO:0032982) |
0.0 | 14.9 | GO:0048471 | perinuclear region of cytoplasm(GO:0048471) |
0.0 | 0.6 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.0 | 0.6 | GO:0031519 | PcG protein complex(GO:0031519) |
0.0 | 1.9 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.0 | 0.3 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
0.0 | 0.3 | GO:0000808 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
0.0 | 0.8 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.0 | 0.3 | GO:0000178 | exosome (RNase complex)(GO:0000178) |
0.0 | 1.5 | GO:0044853 | caveola(GO:0005901) plasma membrane raft(GO:0044853) |
0.0 | 0.7 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
0.0 | 1.8 | GO:0034707 | chloride channel complex(GO:0034707) |
0.0 | 0.7 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
0.0 | 0.2 | GO:0032039 | integrator complex(GO:0032039) |
0.0 | 0.5 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
0.0 | 0.6 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
0.0 | 9.1 | GO:0005625 | obsolete soluble fraction(GO:0005625) |
0.0 | 0.4 | GO:0097060 | synaptic membrane(GO:0097060) |
0.0 | 0.3 | GO:0042101 | T cell receptor complex(GO:0042101) |
0.0 | 0.4 | GO:0071565 | nBAF complex(GO:0071565) |
0.0 | 0.5 | GO:0044665 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
0.0 | 0.6 | GO:0030532 | small nuclear ribonucleoprotein complex(GO:0030532) |
0.0 | 1.5 | GO:0000151 | ubiquitin ligase complex(GO:0000151) |
0.0 | 1.2 | GO:0005770 | late endosome(GO:0005770) |
0.0 | 0.8 | GO:0042645 | mitochondrial nucleoid(GO:0042645) |
0.0 | 0.4 | GO:0008287 | protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293) |
0.0 | 3.4 | GO:0000785 | chromatin(GO:0000785) |
0.0 | 0.5 | GO:0005884 | actin filament(GO:0005884) |
0.0 | 0.4 | GO:0030018 | Z disc(GO:0030018) |
0.0 | 2.1 | GO:0031965 | nuclear membrane(GO:0031965) |
0.0 | 1.5 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
0.0 | 0.0 | GO:0000221 | vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221) |
0.0 | 0.9 | GO:0098857 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
0.0 | 0.1 | GO:0033270 | paranode region of axon(GO:0033270) |
0.0 | 0.1 | GO:0048786 | presynaptic active zone(GO:0048786) |
0.0 | 0.1 | GO:0030061 | mitochondrial crista(GO:0030061) |
0.0 | 0.9 | GO:0005624 | obsolete membrane fraction(GO:0005624) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 1.8 | GO:0008523 | sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) |
0.5 | 2.0 | GO:0042608 | T cell receptor binding(GO:0042608) |
0.5 | 3.5 | GO:0008107 | galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127) |
0.5 | 1.9 | GO:0004142 | diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307) |
0.5 | 2.4 | GO:0005113 | patched binding(GO:0005113) |
0.5 | 4.7 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
0.5 | 3.7 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
0.4 | 2.1 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
0.4 | 1.2 | GO:0035276 | ethanol binding(GO:0035276) |
0.4 | 1.2 | GO:0001618 | virus receptor activity(GO:0001618) |
0.4 | 2.7 | GO:0004703 | G-protein coupled receptor kinase activity(GO:0004703) |
0.4 | 1.5 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
0.4 | 1.9 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
0.4 | 1.4 | GO:0051996 | farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996) |
0.4 | 1.4 | GO:0016822 | hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823) |
0.3 | 1.0 | GO:0042289 | MHC class II protein binding(GO:0042289) |
0.3 | 4.3 | GO:0019992 | diacylglycerol binding(GO:0019992) |
0.3 | 0.9 | GO:0033878 | hormone-sensitive lipase activity(GO:0033878) |
0.3 | 1.7 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
0.3 | 2.5 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
0.2 | 1.1 | GO:0004883 | glucocorticoid receptor activity(GO:0004883) |
0.2 | 0.9 | GO:0070996 | type 1 melanocortin receptor binding(GO:0070996) |
0.2 | 0.6 | GO:0005174 | CD40 receptor binding(GO:0005174) |
0.2 | 0.9 | GO:0004517 | nitric-oxide synthase activity(GO:0004517) |
0.2 | 0.6 | GO:0004949 | cannabinoid receptor activity(GO:0004949) |
0.2 | 3.7 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) |
0.2 | 0.6 | GO:0035198 | miRNA binding(GO:0035198) |
0.2 | 1.8 | GO:0019237 | centromeric DNA binding(GO:0019237) |
0.2 | 0.6 | GO:0004796 | thromboxane-A synthase activity(GO:0004796) |
0.2 | 1.3 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
0.2 | 0.7 | GO:0043398 | HLH domain binding(GO:0043398) |
0.2 | 0.7 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
0.2 | 1.3 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813) |
0.2 | 6.3 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
0.2 | 4.4 | GO:0070888 | E-box binding(GO:0070888) |
0.1 | 0.6 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
0.1 | 0.7 | GO:0003680 | AT DNA binding(GO:0003680) |
0.1 | 1.2 | GO:0031489 | myosin V binding(GO:0031489) |
0.1 | 0.5 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
0.1 | 0.5 | GO:0004663 | Rab geranylgeranyltransferase activity(GO:0004663) |
0.1 | 0.5 | GO:0004346 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
0.1 | 1.6 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
0.1 | 0.5 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970) |
0.1 | 0.8 | GO:0030506 | ankyrin binding(GO:0030506) |
0.1 | 0.4 | GO:0003870 | 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749) |
0.1 | 1.5 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
0.1 | 1.0 | GO:0004969 | histamine receptor activity(GO:0004969) |
0.1 | 0.8 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
0.1 | 8.9 | GO:0051015 | actin filament binding(GO:0051015) |
0.1 | 0.5 | GO:0017163 | obsolete basal transcription repressor activity(GO:0017163) |
0.1 | 4.6 | GO:0008601 | protein phosphatase type 2A regulator activity(GO:0008601) |
0.1 | 1.8 | GO:0017025 | TBP-class protein binding(GO:0017025) |
0.1 | 1.6 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
0.1 | 0.4 | GO:0004998 | transferrin receptor activity(GO:0004998) |
0.1 | 0.7 | GO:0031432 | titin binding(GO:0031432) |
0.1 | 0.5 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
0.1 | 0.4 | GO:0004727 | prenylated protein tyrosine phosphatase activity(GO:0004727) |
0.1 | 0.6 | GO:0017050 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
0.1 | 0.9 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
0.1 | 1.4 | GO:0050786 | RAGE receptor binding(GO:0050786) |
0.1 | 0.5 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
0.1 | 0.3 | GO:0016211 | glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880) |
0.1 | 0.9 | GO:0033612 | receptor serine/threonine kinase binding(GO:0033612) |
0.1 | 4.3 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
0.1 | 0.5 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
0.1 | 1.0 | GO:0005344 | oxygen transporter activity(GO:0005344) |
0.1 | 0.5 | GO:0050682 | AF-2 domain binding(GO:0050682) |
0.1 | 0.3 | GO:0050693 | LBD domain binding(GO:0050693) |
0.1 | 0.5 | GO:0004046 | aminoacylase activity(GO:0004046) |
0.1 | 0.4 | GO:0008649 | rRNA methyltransferase activity(GO:0008649) |
0.1 | 0.4 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
0.1 | 0.3 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
0.1 | 3.2 | GO:0030145 | manganese ion binding(GO:0030145) |
0.1 | 0.6 | GO:0016494 | C-X-C chemokine receptor activity(GO:0016494) |
0.1 | 0.9 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
0.1 | 0.8 | GO:0010181 | FMN binding(GO:0010181) |
0.1 | 0.8 | GO:0016634 | oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634) |
0.1 | 0.6 | GO:0031013 | troponin I binding(GO:0031013) |
0.1 | 1.6 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.1 | 2.1 | GO:0050699 | WW domain binding(GO:0050699) |
0.1 | 0.1 | GO:0043559 | insulin binding(GO:0043559) |
0.1 | 0.6 | GO:0030297 | transmembrane receptor protein tyrosine kinase activator activity(GO:0030297) |
0.1 | 0.3 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
0.1 | 1.3 | GO:0051018 | protein kinase A binding(GO:0051018) |
0.1 | 0.3 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
0.1 | 6.2 | GO:0016566 | obsolete specific transcriptional repressor activity(GO:0016566) |
0.1 | 0.6 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
0.1 | 2.3 | GO:0017137 | Rab GTPase binding(GO:0017137) |
0.1 | 0.9 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.1 | 0.7 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
0.1 | 0.5 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
0.1 | 0.4 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
0.1 | 0.2 | GO:0033265 | choline binding(GO:0033265) |
0.0 | 1.2 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
0.0 | 5.2 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.0 | 0.3 | GO:0004875 | complement receptor activity(GO:0004875) |
0.0 | 5.9 | GO:0005179 | hormone activity(GO:0005179) |
0.0 | 1.8 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
0.0 | 1.3 | GO:0008656 | cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) |
0.0 | 0.1 | GO:0005152 | interleukin-1 receptor antagonist activity(GO:0005152) |
0.0 | 0.2 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
0.0 | 0.1 | GO:0010861 | thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375) |
0.0 | 0.3 | GO:0030911 | TPR domain binding(GO:0030911) |
0.0 | 0.3 | GO:0031404 | chloride ion binding(GO:0031404) |
0.0 | 0.1 | GO:0031711 | angiotensin type I receptor activity(GO:0001596) acetyltransferase activator activity(GO:0010698) bradykinin receptor binding(GO:0031711) |
0.0 | 0.2 | GO:0042132 | fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132) |
0.0 | 0.4 | GO:0055103 | ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106) |
0.0 | 0.4 | GO:0004117 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) |
0.0 | 2.2 | GO:0050136 | NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.0 | 0.3 | GO:0001591 | dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) |
0.0 | 0.9 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
0.0 | 0.2 | GO:0004992 | platelet activating factor receptor activity(GO:0004992) |
0.0 | 1.0 | GO:0004713 | protein tyrosine kinase activity(GO:0004713) |
0.0 | 0.5 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
0.0 | 0.3 | GO:0008312 | 7S RNA binding(GO:0008312) |
0.0 | 4.6 | GO:0017124 | SH3 domain binding(GO:0017124) |
0.0 | 0.0 | GO:0034979 | NAD-dependent protein deacetylase activity(GO:0034979) |
0.0 | 0.7 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
0.0 | 0.2 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
0.0 | 0.3 | GO:0070053 | thrombospondin receptor activity(GO:0070053) |
0.0 | 0.7 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
0.0 | 0.8 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
0.0 | 1.6 | GO:0008094 | DNA-dependent ATPase activity(GO:0008094) |
0.0 | 0.5 | GO:0008200 | ion channel inhibitor activity(GO:0008200) |
0.0 | 0.2 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
0.0 | 0.7 | GO:0004697 | protein kinase C activity(GO:0004697) |
0.0 | 0.1 | GO:0005224 | ATP-binding and phosphorylation-dependent chloride channel activity(GO:0005224) channel-conductance-controlling ATPase activity(GO:0005260) |
0.0 | 0.9 | GO:0045296 | cadherin binding(GO:0045296) |
0.0 | 0.3 | GO:0003688 | DNA replication origin binding(GO:0003688) |
0.0 | 1.8 | GO:0030165 | PDZ domain binding(GO:0030165) |
0.0 | 0.3 | GO:0051400 | BH domain binding(GO:0051400) |
0.0 | 0.2 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
0.0 | 0.2 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
0.0 | 0.5 | GO:0005537 | mannose binding(GO:0005537) |
0.0 | 0.1 | GO:0003956 | NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956) |
0.0 | 0.5 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.0 | 1.2 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
0.0 | 0.1 | GO:0019834 | phospholipase A2 inhibitor activity(GO:0019834) |
0.0 | 0.3 | GO:0004000 | adenosine deaminase activity(GO:0004000) |
0.0 | 0.2 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) |
0.0 | 0.2 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
0.0 | 0.4 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
0.0 | 0.1 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
0.0 | 0.3 | GO:0000339 | RNA cap binding(GO:0000339) |
0.0 | 0.1 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
0.0 | 0.1 | GO:0004995 | tachykinin receptor activity(GO:0004995) |
0.0 | 0.2 | GO:0031701 | angiotensin receptor binding(GO:0031701) |
0.0 | 0.1 | GO:1990782 | receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782) |
0.0 | 0.3 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.0 | 0.1 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
0.0 | 0.1 | GO:0005223 | intracellular cGMP activated cation channel activity(GO:0005223) |
0.0 | 0.2 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
0.0 | 0.1 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
0.0 | 0.7 | GO:0002039 | p53 binding(GO:0002039) |
0.0 | 0.4 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
0.0 | 0.2 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
0.0 | 0.2 | GO:0003709 | obsolete RNA polymerase III transcription factor activity(GO:0003709) |
0.0 | 0.2 | GO:0001614 | purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502) |
0.0 | 0.1 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
0.0 | 0.7 | GO:0042393 | histone binding(GO:0042393) |
0.0 | 0.5 | GO:0042826 | histone deacetylase binding(GO:0042826) |
0.0 | 0.3 | GO:0005003 | ephrin receptor activity(GO:0005003) |
0.0 | 4.7 | GO:0019904 | protein domain specific binding(GO:0019904) |
0.0 | 0.2 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
0.0 | 3.6 | GO:0046982 | protein heterodimerization activity(GO:0046982) |
0.0 | 0.2 | GO:0015101 | organic cation transmembrane transporter activity(GO:0015101) |
0.0 | 0.2 | GO:0051635 | obsolete bacterial cell surface binding(GO:0051635) |
0.0 | 0.2 | GO:0004859 | phospholipase inhibitor activity(GO:0004859) |
0.0 | 0.3 | GO:0005158 | insulin receptor binding(GO:0005158) |
0.0 | 0.3 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
0.0 | 0.4 | GO:0008066 | glutamate receptor activity(GO:0008066) |
0.0 | 0.2 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
0.0 | 0.0 | GO:0004914 | interleukin-5 receptor activity(GO:0004914) |
0.0 | 0.8 | GO:0005254 | chloride channel activity(GO:0005254) |
0.0 | 0.0 | GO:0017160 | Ral GTPase binding(GO:0017160) |
0.0 | 0.1 | GO:0016018 | cyclosporin A binding(GO:0016018) |
0.0 | 0.1 | GO:0004849 | uridine kinase activity(GO:0004849) |
0.0 | 0.0 | GO:0008502 | melatonin receptor activity(GO:0008502) |
0.0 | 0.1 | GO:0050780 | dopamine receptor binding(GO:0050780) |
0.0 | 0.0 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
0.0 | 0.2 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
0.0 | 0.1 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
0.0 | 0.2 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.0 | 0.3 | GO:0004385 | guanylate kinase activity(GO:0004385) |
0.0 | 0.2 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
0.0 | 0.2 | GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555) |
0.0 | 0.1 | GO:0015385 | sodium:proton antiporter activity(GO:0015385) |
0.0 | 0.1 | GO:0016638 | oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 3.6 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
0.1 | 12.3 | ST_T_CELL_SIGNAL_TRANSDUCTION | T Cell Signal Transduction |
0.1 | 2.3 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
0.0 | 0.7 | SA_TRKA_RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
0.0 | 0.8 | SA_B_CELL_RECEPTOR_COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
0.0 | 1.4 | ST_P38_MAPK_PATHWAY | p38 MAPK Pathway |
0.0 | 0.4 | ST_TYPE_I_INTERFERON_PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
0.0 | 0.7 | SA_G1_AND_S_PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
0.0 | 0.7 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
0.0 | 0.2 | ST_GRANULE_CELL_SURVIVAL_PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
0.0 | 0.3 | SA_FAS_SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
0.0 | 0.7 | SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
0.0 | 0.2 | SA_PROGRAMMED_CELL_DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
0.0 | 0.2 | SIG_CHEMOTAXIS | Genes related to chemotaxis |