Motif ID: FOXO3_FOXD2

Z-value: 1.827

Transcription factors associated with FOXO3_FOXD2:

Gene SymbolEntrez IDGene Name
FOXD2 ENSG00000186564.5 FOXD2
FOXO3 ENSG00000118689.10 FOXO3






Network of associatons between targets according to the STRING database.



First level regulatory network of FOXO3_FOXD2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_99698338 5.393 ENST00000354230.3
ENST00000425308.1
MCM7

minichromosome maintenance complex component 7

chr13_-_46716969 5.160 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr8_-_80993010 4.880 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
TPD52




tumor protein D52




chr2_-_158345462 4.249 ENST00000439355.1
ENST00000540637.1
CYTIP

cytohesin 1 interacting protein

chr13_-_46756351 3.995 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr12_-_772901 3.505 ENST00000305108.4
NINJ2
ninjurin 2
chr6_+_135502408 3.458 ENST00000341911.5
ENST00000442647.2
ENST00000316528.8
MYB


v-myb avian myeloblastosis viral oncogene homolog


chr2_+_33661382 3.387 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr6_+_135502466 3.334 ENST00000367814.4
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr2_-_152146385 2.851 ENST00000414946.1
ENST00000243346.5
NMI

N-myc (and STAT) interactor

chr14_-_21493649 2.810 ENST00000553442.1
ENST00000555869.1
ENST00000556457.1
ENST00000397844.2
ENST00000554415.1
NDRG2




NDRG family member 2




chr17_-_29641104 2.601 ENST00000577894.1
ENST00000330927.4
EVI2B

ecotropic viral integration site 2B

chr7_-_37026108 2.558 ENST00000396045.3
ELMO1
engulfment and cell motility 1
chr6_-_42016385 2.518 ENST00000502771.1
ENST00000508143.1
ENST00000514588.1
ENST00000510503.1
ENST00000415497.2
ENST00000372988.4
CCND3





cyclin D3





chr11_+_10476851 2.517 ENST00000396553.2
AMPD3
adenosine monophosphate deaminase 3
chr22_+_40342819 2.478 ENST00000407075.3
GRAP2
GRB2-related adaptor protein 2
chr17_+_65373531 2.386 ENST00000580974.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr4_-_105416039 2.376 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr17_+_65374075 2.297 ENST00000581322.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr17_-_38721711 2.179 ENST00000578085.1
ENST00000246657.2
CCR7

chemokine (C-C motif) receptor 7

chr8_+_26150628 2.158 ENST00000523925.1
ENST00000315985.7
PPP2R2A

protein phosphatase 2, regulatory subunit B, alpha

chr5_-_137674000 2.103 ENST00000510119.1
ENST00000513970.1
CDC25C

cell division cycle 25C

chr7_+_116654935 2.080 ENST00000432298.1
ENST00000422922.1
ST7

suppression of tumorigenicity 7

chr17_-_29641084 2.070 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr3_-_141868293 2.054 ENST00000317104.7
ENST00000494358.1
TFDP2

transcription factor Dp-2 (E2F dimerization partner 2)

chr5_+_169064245 2.049 ENST00000256935.8
DOCK2
dedicator of cytokinesis 2
chr1_+_111682058 1.944 ENST00000545121.1
CEPT1
choline/ethanolamine phosphotransferase 1
chr12_-_92539614 1.937 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr6_+_135502501 1.888 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB






v-myb avian myeloblastosis viral oncogene homolog






chr7_-_140624499 1.873 ENST00000288602.6
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr8_-_29208183 1.864 ENST00000240100.2
DUSP4
dual specificity phosphatase 4
chr10_+_97515409 1.852 ENST00000371207.3
ENST00000543964.1
ENTPD1

ectonucleoside triphosphate diphosphohydrolase 1

chr6_+_125540951 1.816 ENST00000524679.1
TPD52L1
tumor protein D52-like 1
chr3_-_33700589 1.794 ENST00000461133.3
ENST00000496954.2
CLASP2

cytoplasmic linker associated protein 2

chr2_-_27435125 1.763 ENST00000414408.1
ENST00000310574.3
SLC5A6

solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6

chr1_+_192544857 1.758 ENST00000367459.3
ENST00000469578.2
RGS1

regulator of G-protein signaling 1

chr6_-_89927151 1.753 ENST00000454853.2
GABRR1
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr10_-_14050522 1.721 ENST00000342409.2
FRMD4A
FERM domain containing 4A
chr3_-_33700933 1.721 ENST00000480013.1
CLASP2
cytoplasmic linker associated protein 2
chr3_-_141868357 1.714 ENST00000489671.1
ENST00000475734.1
ENST00000467072.1
ENST00000499676.2
TFDP2



transcription factor Dp-2 (E2F dimerization partner 2)



chr12_-_102591604 1.655 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr1_-_117210290 1.640 ENST00000369483.1
ENST00000369486.3
IGSF3

immunoglobulin superfamily, member 3

chr12_-_31479045 1.615 ENST00000539409.1
ENST00000395766.1
FAM60A

family with sequence similarity 60, member A

chr9_-_37034028 1.606 ENST00000520281.1
ENST00000446742.1
ENST00000522003.1
ENST00000523145.1
ENST00000414447.1
ENST00000377847.2
ENST00000377853.2
ENST00000377852.2
ENST00000523241.1
ENST00000520154.1
ENST00000358127.4
PAX5










paired box 5










chr8_+_99956662 1.576 ENST00000523368.1
ENST00000297565.4
ENST00000435298.2
OSR2


odd-skipped related transciption factor 2


chr4_-_103266626 1.556 ENST00000356736.4
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr1_-_207095324 1.546 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
FAIM3


Fas apoptotic inhibitory molecule 3


chr2_+_58655461 1.534 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
AC007092.1


long intergenic non-protein coding RNA 1122


chr4_-_116034979 1.515 ENST00000264363.2
NDST4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr12_-_28123206 1.469 ENST00000542963.1
ENST00000535992.1
PTHLH

parathyroid hormone-like hormone

chr6_+_6588902 1.460 ENST00000230568.4
LY86
lymphocyte antigen 86
chr12_+_25205666 1.447 ENST00000547044.1
LRMP
lymphoid-restricted membrane protein
chr8_+_11666649 1.445 ENST00000528643.1
ENST00000525777.1
FDFT1

farnesyl-diphosphate farnesyltransferase 1

chr8_+_126442563 1.438 ENST00000311922.3
TRIB1
tribbles pseudokinase 1
chr5_+_176853669 1.412 ENST00000355472.5
GRK6
G protein-coupled receptor kinase 6
chr15_+_81589254 1.391 ENST00000394652.2
IL16
interleukin 16
chr10_-_99094458 1.378 ENST00000371019.2
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr5_+_176853702 1.327 ENST00000507633.1
ENST00000393576.3
ENST00000355958.5
ENST00000528793.1
ENST00000512684.1
GRK6




G protein-coupled receptor kinase 6




chr8_-_28243934 1.327 ENST00000521185.1
ENST00000520290.1
ENST00000344423.5
ZNF395


zinc finger protein 395


chr8_+_128748466 1.293 ENST00000524013.1
ENST00000520751.1
MYC

v-myc avian myelocytomatosis viral oncogene homolog

chr17_-_39942940 1.286 ENST00000310706.5
ENST00000393931.3
ENST00000424457.1
ENST00000591690.1
JUP



junction plakoglobin



chr12_-_28122980 1.280 ENST00000395868.3
ENST00000534890.1
PTHLH

parathyroid hormone-like hormone

chr5_-_169725231 1.272 ENST00000046794.5
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr1_-_207095212 1.272 ENST00000420007.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr16_+_12058961 1.267 ENST00000053243.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr12_-_28124903 1.235 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
PTHLH


parathyroid hormone-like hormone


chr8_+_77593448 1.222 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr15_-_55541227 1.219 ENST00000566877.1
RAB27A
RAB27A, member RAS oncogene family
chr16_+_12059050 1.215 ENST00000396495.3
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr8_+_128748308 1.213 ENST00000377970.2
MYC
v-myc avian myelocytomatosis viral oncogene homolog
chrX_-_15619076 1.197 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chr16_+_12059091 1.195 ENST00000562385.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr1_-_54405773 1.189 ENST00000371376.1
HSPB11
heat shock protein family B (small), member 11
chr1_+_199996702 1.187 ENST00000367362.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr8_-_95449155 1.182 ENST00000481490.2
FSBP
fibrinogen silencer binding protein
chr14_-_21493884 1.179 ENST00000556974.1
ENST00000554419.1
ENST00000298687.5
ENST00000397858.1
ENST00000360463.3
ENST00000350792.3
ENST00000397847.2
NDRG2






NDRG family member 2






chr18_+_57567180 1.175 ENST00000316660.6
ENST00000269518.9
PMAIP1

phorbol-12-myristate-13-acetate-induced protein 1

chr7_+_129906660 1.165 ENST00000222481.4
CPA2
carboxypeptidase A2 (pancreatic)
chr5_-_115872142 1.143 ENST00000510263.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr6_+_32121789 1.128 ENST00000437001.2
ENST00000375137.2
PPT2

palmitoyl-protein thioesterase 2

chr1_+_158815588 1.113 ENST00000438394.1
MNDA
myeloid cell nuclear differentiation antigen
chr14_-_36988882 1.109 ENST00000498187.2
NKX2-1
NK2 homeobox 1
chr7_-_37024665 1.106 ENST00000396040.2
ELMO1
engulfment and cell motility 1
chr9_-_98269481 1.074 ENST00000418258.1
ENST00000553011.1
ENST00000551845.1
PTCH1


patched 1


chr2_+_86947296 1.068 ENST00000283632.4
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr13_-_31038370 1.045 ENST00000399489.1
ENST00000339872.4
HMGB1

high mobility group box 1

chr11_-_72070206 1.034 ENST00000544382.1
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr10_-_43904608 1.028 ENST00000337970.3
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr7_+_134832808 1.017 ENST00000275767.3
TMEM140
transmembrane protein 140
chr11_-_5526834 1.011 ENST00000380252.1
ENST00000380237.1
ENST00000396895.1
HBG2
HBE1

hemoglobin, gamma G
hemoglobin, epsilon 1

chr6_-_136847099 1.009 ENST00000438100.2
MAP7
microtubule-associated protein 7
chr12_+_6881678 1.009 ENST00000441671.2
ENST00000203629.2
LAG3

lymphocyte-activation gene 3

chr17_+_67410832 1.002 ENST00000590474.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr6_+_32121908 0.999 ENST00000375143.2
ENST00000424499.1
PPT2

palmitoyl-protein thioesterase 2

chr20_+_62795827 0.996 ENST00000328439.1
ENST00000536311.1
MYT1

myelin transcription factor 1

chr2_-_74007193 0.988 ENST00000377706.4
ENST00000443070.1
ENST00000272444.3
DUSP11


dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)


chr11_-_108464321 0.987 ENST00000265843.4
EXPH5
exophilin 5
chr20_+_52105495 0.981 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr2_-_160472952 0.966 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
BAZ2B



bromodomain adjacent to zinc finger domain, 2B



chr4_-_153303658 0.958 ENST00000296555.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr2_-_172750733 0.957 ENST00000392592.4
ENST00000422440.2
SLC25A12

solute carrier family 25 (aspartate/glutamate carrier), member 12

chr8_-_8318847 0.956 ENST00000521218.1
CTA-398F10.2
CTA-398F10.2
chrX_-_133792480 0.953 ENST00000359237.4
PLAC1
placenta-specific 1
chr6_-_13621126 0.952 ENST00000600057.1
AL441883.1
Uncharacterized protein
chr1_-_111743285 0.947 ENST00000357640.4
DENND2D
DENN/MADD domain containing 2D
chr15_+_41549105 0.945 ENST00000560965.1
CHP1
calcineurin-like EF-hand protein 1
chr19_-_42916499 0.942 ENST00000601189.1
ENST00000599211.1
LIPE

lipase, hormone-sensitive

chr11_-_108464465 0.940 ENST00000525344.1
EXPH5
exophilin 5
chrX_+_9431324 0.933 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X





transducin (beta)-like 1X-linked





chr19_-_39826639 0.931 ENST00000602185.1
ENST00000598034.1
ENST00000601387.1
ENST00000595636.1
ENST00000253054.8
ENST00000594700.1
ENST00000597595.1
GMFG






glia maturation factor, gamma






chr22_+_40322595 0.928 ENST00000420971.1
ENST00000544756.1
GRAP2

GRB2-related adaptor protein 2

chr2_+_33701286 0.920 ENST00000403687.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr1_+_45212051 0.920 ENST00000372222.3
KIF2C
kinesin family member 2C
chr6_-_136847610 0.920 ENST00000454590.1
ENST00000432797.2
MAP7

microtubule-associated protein 7

chr22_+_40322623 0.912 ENST00000399090.2
GRAP2
GRB2-related adaptor protein 2
chr5_-_98262240 0.911 ENST00000284049.3
CHD1
chromodomain helicase DNA binding protein 1
chr4_-_140223670 0.909 ENST00000394228.1
ENST00000539387.1
NDUFC1

NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa

chr10_-_121296045 0.900 ENST00000392865.1
RGS10
regulator of G-protein signaling 10
chr2_-_170430277 0.899 ENST00000438035.1
ENST00000453929.2
FASTKD1

FAST kinase domains 1

chr4_-_123542224 0.894 ENST00000264497.3
IL21
interleukin 21
chr2_-_170430366 0.891 ENST00000453153.2
ENST00000445210.1
FASTKD1

FAST kinase domains 1

chr2_-_165424973 0.888 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chr14_-_21493123 0.871 ENST00000556147.1
ENST00000554489.1
ENST00000555657.1
ENST00000557274.1
ENST00000555158.1
ENST00000554833.1
ENST00000555384.1
ENST00000556420.1
ENST00000554893.1
ENST00000553503.1
ENST00000555733.1
ENST00000553867.1
ENST00000397856.3
ENST00000397855.3
ENST00000556008.1
ENST00000557182.1
ENST00000554483.1
ENST00000556688.1
ENST00000397853.3
ENST00000556329.2
ENST00000554143.1
ENST00000397851.2
ENST00000555142.1
ENST00000557676.1
ENST00000556924.1
NDRG2
























NDRG family member 2
























chr16_-_4323015 0.865 ENST00000204517.6
TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr1_+_45212074 0.864 ENST00000372217.1
KIF2C
kinesin family member 2C
chr5_-_40755987 0.863 ENST00000337702.4
TTC33
tetratricopeptide repeat domain 33
chr4_-_168155169 0.862 ENST00000534949.1
ENST00000535728.1
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr21_-_43816152 0.857 ENST00000433957.2
ENST00000398397.3
TMPRSS3

transmembrane protease, serine 3

chr5_-_142783175 0.856 ENST00000231509.3
ENST00000394464.2
NR3C1

nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

chr2_+_68592305 0.851 ENST00000234313.7
PLEK
pleckstrin
chr6_-_31550192 0.849 ENST00000429299.2
ENST00000446745.2
LTB

lymphotoxin beta (TNF superfamily, member 3)

chr17_+_38333263 0.845 ENST00000456989.2
ENST00000543876.1
ENST00000544503.1
ENST00000264644.6
ENST00000538884.1
RAPGEFL1




Rap guanine nucleotide exchange factor (GEF)-like 1




chr2_+_143635067 0.845 ENST00000264170.4
KYNU
kynureninase
chr3_+_178866199 0.844 ENST00000263967.3
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr15_+_81475047 0.838 ENST00000559388.1
IL16
interleukin 16
chr17_-_42345487 0.832 ENST00000262418.6
SLC4A1
solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
chr9_+_139702363 0.828 ENST00000371663.4
ENST00000371671.4
ENST00000311502.7
RABL6


RAB, member RAS oncogene family-like 6


chr5_-_131132658 0.828 ENST00000511848.1
ENST00000510461.1
ENST00000514667.1
FNIP1

CTC-432M15.3
folliculin interacting protein 1

Folliculin-interacting protein 1
chr4_+_88720698 0.827 ENST00000226284.5
IBSP
integrin-binding sialoprotein
chrX_+_37639302 0.825 ENST00000545017.1
ENST00000536160.1
CYBB

cytochrome b-245, beta polypeptide

chr21_-_33975547 0.825 ENST00000431599.1
C21orf59
chromosome 21 open reading frame 59
chr1_+_161136180 0.822 ENST00000352210.5
ENST00000367999.4
ENST00000544598.1
ENST00000535223.1
ENST00000432542.2
PPOX




protoporphyrinogen oxidase




chr10_-_43904235 0.816 ENST00000356053.3
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr2_-_112614424 0.815 ENST00000427997.1
ANAPC1
anaphase promoting complex subunit 1
chr9_-_128246769 0.813 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr7_+_28725585 0.805 ENST00000396298.2
CREB5
cAMP responsive element binding protein 5
chr1_-_114414316 0.803 ENST00000528414.1
ENST00000538253.1
ENST00000460620.1
ENST00000420377.2
ENST00000525799.1
ENST00000359785.5
PTPN22





protein tyrosine phosphatase, non-receptor type 22 (lymphoid)





chr18_-_53070913 0.801 ENST00000568186.1
ENST00000564228.1
TCF4

transcription factor 4

chr5_-_16509101 0.799 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr3_-_57233966 0.794 ENST00000473921.1
ENST00000295934.3
HESX1

HESX homeobox 1

chr14_-_58894332 0.787 ENST00000395159.2
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr11_+_117049910 0.787 ENST00000431081.2
ENST00000524842.1
SIDT2

SID1 transmembrane family, member 2

chr19_+_859654 0.780 ENST00000592860.1
CFD
complement factor D (adipsin)
chr9_-_3525968 0.774 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
RFX3


regulatory factor X, 3 (influences HLA class II expression)


chr2_-_157198860 0.772 ENST00000409572.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr3_-_107777208 0.766 ENST00000398258.3
CD47
CD47 molecule
chr1_+_86934526 0.765 ENST00000394711.1
CLCA1
chloride channel accessory 1
chr13_-_99910673 0.764 ENST00000397473.2
ENST00000397470.2
GPR18

G protein-coupled receptor 18

chrX_+_37639264 0.759 ENST00000378588.4
CYBB
cytochrome b-245, beta polypeptide
chrX_-_48776292 0.757 ENST00000376509.4
PIM2
pim-2 oncogene
chr21_-_34186006 0.752 ENST00000490358.1
C21orf62
chromosome 21 open reading frame 62
chr9_+_27109133 0.744 ENST00000519097.1
ENST00000380036.4
TEK

TEK tyrosine kinase, endothelial

chr6_-_32634425 0.742 ENST00000399082.3
ENST00000399079.3
ENST00000374943.4
ENST00000434651.2
HLA-DQB1



major histocompatibility complex, class II, DQ beta 1



chr16_+_30483962 0.742 ENST00000356798.6
ITGAL
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr3_+_136649311 0.738 ENST00000469404.1
ENST00000467911.1
NCK1

NCK adaptor protein 1

chr8_-_40755333 0.737 ENST00000297737.6
ENST00000315769.7
ZMAT4

zinc finger, matrin-type 4

chr3_-_168865522 0.737 ENST00000464456.1
MECOM
MDS1 and EVI1 complex locus
chr14_+_61788429 0.734 ENST00000332981.5
PRKCH
protein kinase C, eta
chr14_+_32798462 0.730 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr6_+_106546808 0.728 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr3_+_193853927 0.726 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr9_-_98269699 0.721 ENST00000429896.2
PTCH1
patched 1
chr14_+_60716159 0.721 ENST00000325658.3
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr1_-_202927490 0.713 ENST00000340990.5
ADIPOR1
adiponectin receptor 1
chr8_+_86121448 0.704 ENST00000520225.1
E2F5
E2F transcription factor 5, p130-binding
chr12_-_53343602 0.701 ENST00000546897.1
ENST00000552551.1
KRT8

keratin 8

chr21_-_43816052 0.700 ENST00000398405.1
TMPRSS3
transmembrane protease, serine 3
chr1_-_45956800 0.699 ENST00000538496.1
TESK2
testis-specific kinase 2
chr12_+_25205568 0.698 ENST00000548766.1
ENST00000556887.1
LRMP

lymphoid-restricted membrane protein

chr16_+_86612112 0.693 ENST00000320241.3
FOXL1
forkhead box L1
chr16_+_84801852 0.690 ENST00000569925.1
ENST00000567526.1
USP10

ubiquitin specific peptidase 10

chr6_+_34204642 0.690 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1




high mobility group AT-hook 1




chr8_-_127570603 0.690 ENST00000304916.3
FAM84B
family with sequence similarity 84, member B
chr12_-_28125638 0.685 ENST00000545234.1
PTHLH
parathyroid hormone-like hormone
chr1_+_65730385 0.681 ENST00000263441.7
ENST00000395325.3
DNAJC6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr3_-_49066811 0.680 ENST00000442157.1
ENST00000326739.4
IMPDH2

IMP (inosine 5'-monophosphate) dehydrogenase 2

chr4_+_87928140 0.676 ENST00000307808.6
AFF1
AF4/FMR2 family, member 1
chr1_-_161102213 0.675 ENST00000458050.2
DEDD
death effector domain containing
chr9_+_27109392 0.673 ENST00000406359.4
TEK
TEK tyrosine kinase, endothelial
chr7_+_107384142 0.671 ENST00000440859.3
CBLL1
Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
chr12_-_86650045 0.667 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr12_+_6603253 0.666 ENST00000382457.4
ENST00000545962.1
NCAPD2

non-SMC condensin I complex, subunit D2

chr6_+_112375462 0.664 ENST00000361714.1
WISP3
WNT1 inducible signaling pathway protein 3
chr12_-_86650077 0.658 ENST00000552808.2
ENST00000547225.1
MGAT4C

mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)

chr4_-_140223614 0.649 ENST00000394223.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr8_+_31497271 0.647 ENST00000520407.1
NRG1
neuregulin 1
chr2_-_136875712 0.643 ENST00000241393.3
CXCR4
chemokine (C-X-C motif) receptor 4
chr5_+_112312416 0.639 ENST00000389063.2
DCP2
decapping mRNA 2
chr2_+_44396000 0.632 ENST00000409895.4
ENST00000409432.3
ENST00000282412.4
ENST00000378551.2
ENST00000345249.4
PPM1B




protein phosphatase, Mg2+/Mn2+ dependent, 1B




chr9_-_98279241 0.627 ENST00000437951.1
ENST00000375274.2
ENST00000430669.2
ENST00000468211.2
PTCH1



patched 1




Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.7 GO:0060649 nipple development(GO:0060618) mammary gland bud elongation(GO:0060649) nipple morphogenesis(GO:0060658) nipple sheath formation(GO:0060659)
1.0 1.0 GO:0003006 developmental process involved in reproduction(GO:0003006)
0.8 2.5 GO:1901724 positive regulation of cell proliferation involved in kidney development(GO:1901724)
0.7 2.6 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.6 1.9 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.6 2.5 GO:0010157 response to chlorate(GO:0010157)
0.6 1.8 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.4 1.3 GO:0071603 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) endothelial cell-cell adhesion(GO:0071603)
0.4 2.5 GO:0006196 AMP catabolic process(GO:0006196)
0.4 1.7 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
0.4 1.2 GO:0010430 ethanol catabolic process(GO:0006068) fatty acid omega-oxidation(GO:0010430)
0.4 1.6 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.4 1.2 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.4 2.4 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.4 0.4 GO:0034310 primary alcohol catabolic process(GO:0034310)
0.4 1.4 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.4 1.4 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.4 1.8 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.3 1.4 GO:0021759 globus pallidus development(GO:0021759) menarche(GO:0042696)
0.3 1.3 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.3 0.9 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.3 1.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.3 1.2 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.3 2.6 GO:1900087 traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.3 0.9 GO:0014900 smooth muscle hyperplasia(GO:0014806) muscle hyperplasia(GO:0014900) positive regulation of guanylate cyclase activity(GO:0031284)
0.3 1.8 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.3 0.8 GO:2000078 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287) regulation of type B pancreatic cell development(GO:2000074) positive regulation of type B pancreatic cell development(GO:2000078)
0.3 1.5 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.2 0.7 GO:0001780 neutrophil homeostasis(GO:0001780)
0.2 0.7 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.2 1.4 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.2 10.4 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.2 4.1 GO:0016601 Rac protein signal transduction(GO:0016601)
0.2 1.1 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.2 3.5 GO:0007020 microtubule nucleation(GO:0007020)
0.2 0.7 GO:0072203 kidney mesenchymal cell proliferation(GO:0072135) metanephric mesenchymal cell proliferation involved in metanephros development(GO:0072136) cell proliferation involved in metanephros development(GO:0072203)
0.2 1.7 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.2 0.9 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.2 0.9 GO:0070527 integrin activation(GO:0033622) regulation of integrin activation(GO:0033623) positive regulation of integrin activation(GO:0033625) platelet aggregation(GO:0070527)
0.2 0.4 GO:0045074 negative regulation of interleukin-10 production(GO:0032693) interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.2 1.0 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.2 0.6 GO:0045759 negative regulation of action potential(GO:0045759)
0.2 0.6 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.2 0.8 GO:0032817 regulation of natural killer cell proliferation(GO:0032817)
0.2 2.1 GO:0001706 endoderm formation(GO:0001706)
0.2 0.6 GO:0046521 sphingoid catabolic process(GO:0046521)
0.2 0.5 GO:0070171 negative regulation of histone methylation(GO:0031061) negative regulation of tooth mineralization(GO:0070171)
0.2 0.3 GO:0008050 female courtship behavior(GO:0008050)
0.2 3.5 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.2 0.6 GO:1904037 positive regulation of epithelial cell apoptotic process(GO:1904037) positive regulation of endothelial cell apoptotic process(GO:2000353)
0.2 2.2 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.2 0.6 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.2 0.8 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.2 0.8 GO:0010508 positive regulation of autophagy(GO:0010508)
0.2 1.2 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 0.9 GO:0032825 regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.1 1.0 GO:0015671 oxygen transport(GO:0015671)
0.1 0.4 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 5.4 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.1 0.4 GO:0031034 skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.4 GO:0007518 myoblast fate determination(GO:0007518)
0.1 2.5 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1 3.7 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.1 0.5 GO:0030259 lipid glycosylation(GO:0030259)
0.1 0.4 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.1 0.3 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.4 GO:1904396 regulation of synaptic growth at neuromuscular junction(GO:0008582) regulation of neuromuscular junction development(GO:1904396)
0.1 0.4 GO:0035623 renal glucose absorption(GO:0035623)
0.1 0.5 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.1 2.1 GO:0006906 vesicle fusion(GO:0006906)
0.1 0.5 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.1 2.0 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 0.6 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.6 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.1 0.1 GO:0032656 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656) negative regulation of interleukin-13 production(GO:0032696) negative regulation of interleukin-5 production(GO:0032714)
0.1 0.4 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.4 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 0.7 GO:0048853 forebrain morphogenesis(GO:0048853)
0.1 0.2 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 0.3 GO:0071104 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.1 1.3 GO:0032876 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.1 0.3 GO:0060267 transformation of host cell by virus(GO:0019087) positive regulation of respiratory burst(GO:0060267)
0.1 0.7 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.3 GO:0048865 stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.1 0.8 GO:0048535 positive regulation of interleukin-12 biosynthetic process(GO:0045084) lymph node development(GO:0048535)
0.1 0.3 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416) positive regulation of dopamine receptor signaling pathway(GO:0060161) negative regulation of sodium ion transmembrane transport(GO:1902306) negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.1 1.0 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.1 0.4 GO:0046621 negative regulation of organ growth(GO:0046621)
0.1 1.6 GO:0045730 respiratory burst(GO:0045730)
0.1 0.3 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 1.6 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 0.3 GO:0019056 modulation by virus of host transcription(GO:0019056) regulation of sprouting of injured axon(GO:0048686) positive regulation of sprouting of injured axon(GO:0048687) regulation of axon extension involved in regeneration(GO:0048690) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.1 0.3 GO:0040034 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.1 1.3 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.1 3.9 GO:0070374 positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.1 0.3 GO:0006531 aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.1 0.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.1 0.9 GO:0048585 negative regulation of response to stimulus(GO:0048585)
0.1 2.0 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 1.4 GO:0006959 humoral immune response(GO:0006959)
0.1 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 1.1 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.1 0.7 GO:0001932 regulation of protein phosphorylation(GO:0001932)
0.1 4.8 GO:0030183 B cell differentiation(GO:0030183)
0.1 0.4 GO:0071168 protein localization to chromatin(GO:0071168)
0.1 0.7 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 0.7 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.1 1.2 GO:0030260 entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.1 0.4 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 1.8 GO:0006309 DNA catabolic process, endonucleolytic(GO:0000737) apoptotic DNA fragmentation(GO:0006309)
0.1 0.4 GO:0055009 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.1 0.6 GO:0043497 regulation of protein heterodimerization activity(GO:0043497)
0.1 1.6 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.7 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 6.0 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 0.3 GO:0010447 response to acidic pH(GO:0010447)
0.1 1.1 GO:0042730 fibrinolysis(GO:0042730)
0.1 0.7 GO:0007494 midgut development(GO:0007494)
0.1 0.2 GO:0043276 anoikis(GO:0043276)
0.1 0.5 GO:0050912 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.1 0.6 GO:0045616 regulation of keratinocyte differentiation(GO:0045616)
0.1 0.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 0.9 GO:0034440 fatty acid oxidation(GO:0019395) lipid oxidation(GO:0034440)
0.1 0.5 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.9 GO:0032720 negative regulation of tumor necrosis factor production(GO:0032720) negative regulation of tumor necrosis factor superfamily cytokine production(GO:1903556)
0.1 0.7 GO:0001893 maternal placenta development(GO:0001893)
0.1 0.5 GO:0007141 male meiosis I(GO:0007141)
0.1 1.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.7 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 0.9 GO:0034605 cellular response to heat(GO:0034605)
0.1 2.6 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.7 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.0 0.3 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037) actin filament reorganization(GO:0090527)
0.0 0.3 GO:0001660 fever generation(GO:0001660)
0.0 0.2 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.0 1.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 2.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:0090151 establishment of protein localization to mitochondrial membrane(GO:0090151)
0.0 0.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:2000831 renin-angiotensin regulation of aldosterone production(GO:0002018) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) positive regulation of NAD(P)H oxidase activity(GO:0033864) corticosteroid hormone secretion(GO:0035930) mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846) regulation of mineralocorticoid secretion(GO:2000855) regulation of aldosterone secretion(GO:2000858)
0.0 0.3 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.2 GO:0070071 response to fructose(GO:0009750) proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.0 0.2 GO:0070254 mucus secretion(GO:0070254)
0.0 0.8 GO:0051353 positive regulation of oxidoreductase activity(GO:0051353)
0.0 0.2 GO:0007416 synapse assembly(GO:0007416)
0.0 1.0 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.2 GO:0008228 opsonization(GO:0008228)
0.0 0.5 GO:0019228 neuronal action potential(GO:0019228)
0.0 1.9 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.0 GO:0060684 epithelial-mesenchymal cell signaling(GO:0060684)
0.0 0.5 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.7 GO:0042102 positive regulation of T cell proliferation(GO:0042102)
0.0 0.4 GO:0032438 melanosome organization(GO:0032438) pigment granule organization(GO:0048753)
0.0 0.1 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 2.9 GO:0007163 establishment or maintenance of cell polarity(GO:0007163)
0.0 0.8 GO:0050870 positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 2.8 GO:0097696 JAK-STAT cascade(GO:0007259) STAT cascade(GO:0097696)
0.0 0.3 GO:0060042 retina morphogenesis in camera-type eye(GO:0060042)
0.0 0.2 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.2 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 1.2 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 0.3 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.7 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.4 GO:0001503 ossification(GO:0001503)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.3 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.9 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 1.7 GO:0006968 cellular defense response(GO:0006968)
0.0 0.4 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
0.0 0.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.6 GO:0050806 positive regulation of synaptic transmission(GO:0050806)
0.0 0.2 GO:0016045 detection of bacterium(GO:0016045)
0.0 0.4 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.4 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 2.2 GO:0007204 positive regulation of cytosolic calcium ion concentration(GO:0007204)
0.0 0.5 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.0 4.5 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 0.2 GO:0016180 snRNA processing(GO:0016180)
0.0 0.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.5 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.8 GO:0000080 mitotic G1 phase(GO:0000080)
0.0 0.2 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 0.8 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.7 GO:0007045 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041)
0.0 1.0 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:0043650 glutamate biosynthetic process(GO:0006537) glutamate catabolic process(GO:0006538) dicarboxylic acid biosynthetic process(GO:0043650)
0.0 0.8 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.4 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 0.0 GO:0048840 otolith development(GO:0048840)
0.0 0.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.4 GO:0019098 mating behavior(GO:0007617) reproductive behavior(GO:0019098) multi-organism reproductive behavior(GO:0044705)
0.0 1.7 GO:0007605 sensory perception of sound(GO:0007605)
0.0 1.6 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.8 GO:0019233 sensory perception of pain(GO:0019233)
0.0 0.1 GO:0046520 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.0 0.2 GO:0001754 eye photoreceptor cell differentiation(GO:0001754) eye photoreceptor cell development(GO:0042462)
0.0 0.2 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.6 GO:0016445 somatic diversification of immunoglobulins(GO:0016445)
0.0 0.2 GO:0021549 cerebellum development(GO:0021549)
0.0 0.2 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.0 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.5 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.5 GO:0001892 embryonic placenta development(GO:0001892)
0.0 0.6 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.2 GO:0098657 neurotransmitter uptake(GO:0001504) import into cell(GO:0098657)
0.0 0.1 GO:0007635 chemosensory behavior(GO:0007635)
0.0 1.0 GO:0006821 chloride transport(GO:0006821)
0.0 0.2 GO:0008206 bile acid metabolic process(GO:0008206)
0.0 1.8 GO:0045333 cellular respiration(GO:0045333)
0.0 0.6 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.1 GO:0001960 negative regulation of cytokine-mediated signaling pathway(GO:0001960)
0.0 0.2 GO:0007032 endosome organization(GO:0007032)
0.0 0.8 GO:0061025 membrane fusion(GO:0061025)
0.0 0.3 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.5 GO:1901342 regulation of angiogenesis(GO:0045765) regulation of vasculature development(GO:1901342)
0.0 0.2 GO:0001501 skeletal system development(GO:0001501)
0.0 0.2 GO:0015695 organic cation transport(GO:0015695)
0.0 1.5 GO:0007565 female pregnancy(GO:0007565)
0.0 0.5 GO:0042593 carbohydrate homeostasis(GO:0033500) glucose homeostasis(GO:0042593)
0.0 1.3 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 0.2 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.0 1.3 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.9 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.6 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.6 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.2 GO:0000768 syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.0 0.2 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.7 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.5 GO:0016064 immunoglobulin mediated immune response(GO:0016064)
0.0 0.0 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.1 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.2 GO:0006000 fructose metabolic process(GO:0006000)
0.0 1.5 GO:0007268 chemical synaptic transmission(GO:0007268) anterograde trans-synaptic signaling(GO:0098916) trans-synaptic signaling(GO:0099537)
0.0 0.2 GO:0006098 pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.0 0.2 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.3 GO:0006469 negative regulation of protein kinase activity(GO:0006469)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 9.2 GO:0001891 phagocytic cup(GO:0001891)
0.4 5.4 GO:0042555 MCM complex(GO:0042555)
0.4 3.5 GO:0005828 kinetochore microtubule(GO:0005828)
0.2 1.7 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2 0.6 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.2 1.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.4 GO:0042629 mast cell granule(GO:0042629)
0.1 0.5 GO:0032585 multivesicular body membrane(GO:0032585)
0.1 4.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.4 GO:0030990 intraciliary transport particle(GO:0030990)
0.1 0.9 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304)
0.1 0.7 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 9.5 GO:0016363 nuclear matrix(GO:0016363)
0.1 1.0 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 0.4 GO:0005688 U6 snRNP(GO:0005688)
0.1 0.7 GO:0000796 condensin complex(GO:0000796)
0.1 1.0 GO:0005833 hemoglobin complex(GO:0005833)
0.1 2.6 GO:0034704 calcium channel complex(GO:0034704)
0.1 2.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.4 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 0.4 GO:0008278 cohesin complex(GO:0008278)
0.0 1.7 GO:0031526 brush border membrane(GO:0031526)
0.0 1.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.6 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 3.2 GO:0016020 membrane(GO:0016020)
0.0 1.6 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.2 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.6 GO:0005903 brush border(GO:0005903)
0.0 0.9 GO:0001772 immunological synapse(GO:0001772)
0.0 0.7 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 1.3 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.6 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 5.7 GO:0005769 early endosome(GO:0005769)
0.0 1.0 GO:0005871 kinesin complex(GO:0005871)
0.0 0.8 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 1.2 GO:0005902 microvillus(GO:0005902)
0.0 0.8 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.5 GO:0032982 myosin filament(GO:0032982)
0.0 14.9 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.6 GO:0031519 PcG protein complex(GO:0031519)
0.0 1.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.3 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 1.5 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.8 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.5 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 9.1 GO:0005625 obsolete soluble fraction(GO:0005625)
0.0 0.4 GO:0097060 synaptic membrane(GO:0097060)
0.0 0.3 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.4 GO:0071565 nBAF complex(GO:0071565)
0.0 0.5 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.6 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.0 1.5 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 1.2 GO:0005770 late endosome(GO:0005770)
0.0 0.8 GO:0042645 mitochondrial nucleoid(GO:0042645)
0.0 0.4 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 3.4 GO:0000785 chromatin(GO:0000785)
0.0 0.5 GO:0005884 actin filament(GO:0005884)
0.0 0.4 GO:0030018 Z disc(GO:0030018)
0.0 2.1 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.5 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.0 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.9 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.1 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.9 GO:0005624 obsolete membrane fraction(GO:0005624)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.5 2.0 GO:0042608 T cell receptor binding(GO:0042608)
0.5 3.5 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.5 1.9 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.5 2.4 GO:0005113 patched binding(GO:0005113)
0.5 4.7 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.5 3.7 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.4 2.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.4 1.2 GO:0035276 ethanol binding(GO:0035276)
0.4 1.2 GO:0001618 virus receptor activity(GO:0001618)
0.4 2.7 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.4 1.5 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.4 1.9 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.4 1.4 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.4 1.4 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.3 1.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.3 4.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.3 0.9 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.3 1.7 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.3 2.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 1.1 GO:0004883 glucocorticoid receptor activity(GO:0004883)
0.2 0.9 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.2 0.6 GO:0005174 CD40 receptor binding(GO:0005174)
0.2 0.9 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.2 0.6 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.2 3.7 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.2 0.6 GO:0035198 miRNA binding(GO:0035198)
0.2 1.8 GO:0019237 centromeric DNA binding(GO:0019237)
0.2 0.6 GO:0004796 thromboxane-A synthase activity(GO:0004796)
0.2 1.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 0.7 GO:0043398 HLH domain binding(GO:0043398)
0.2 0.7 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 1.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.2 6.3 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.2 4.4 GO:0070888 E-box binding(GO:0070888)
0.1 0.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.7 GO:0003680 AT DNA binding(GO:0003680)
0.1 1.2 GO:0031489 myosin V binding(GO:0031489)
0.1 0.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.5 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 0.5 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 1.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.1 0.8 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.4 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 1.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 1.0 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 8.9 GO:0051015 actin filament binding(GO:0051015)
0.1 0.5 GO:0017163 obsolete basal transcription repressor activity(GO:0017163)
0.1 4.6 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.1 1.8 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 1.6 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.4 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 0.7 GO:0031432 titin binding(GO:0031432)
0.1 0.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.4 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 0.6 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.9 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 1.4 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 0.5 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.3 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.9 GO:0033612 receptor serine/threonine kinase binding(GO:0033612)
0.1 4.3 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 0.5 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 1.0 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.5 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.3 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.5 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.4 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.1 0.4 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 0.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 3.2 GO:0030145 manganese ion binding(GO:0030145)
0.1 0.6 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.9 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.8 GO:0010181 FMN binding(GO:0010181)
0.1 0.8 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 0.6 GO:0031013 troponin I binding(GO:0031013)
0.1 1.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 2.1 GO:0050699 WW domain binding(GO:0050699)
0.1 0.1 GO:0043559 insulin binding(GO:0043559)
0.1 0.6 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.3 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 1.3 GO:0051018 protein kinase A binding(GO:0051018)
0.1 0.3 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 6.2 GO:0016566 obsolete specific transcriptional repressor activity(GO:0016566)
0.1 0.6 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 2.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 0.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.7 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.5 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.2 GO:0033265 choline binding(GO:0033265)
0.0 1.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 5.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.3 GO:0004875 complement receptor activity(GO:0004875)
0.0 5.9 GO:0005179 hormone activity(GO:0005179)
0.0 1.8 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.3 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.3 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.3 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.1 GO:0031711 angiotensin type I receptor activity(GO:0001596) acetyltransferase activator activity(GO:0010698) bradykinin receptor binding(GO:0031711)
0.0 0.2 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.4 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.4 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 2.2 GO:0050136 NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.9 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.0 1.0 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.0 0.5 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.3 GO:0008312 7S RNA binding(GO:0008312)
0.0 4.6 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.0 GO:0034979 NAD-dependent protein deacetylase activity(GO:0034979)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.3 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.7 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.6 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.5 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.7 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0005224 ATP-binding and phosphorylation-dependent chloride channel activity(GO:0005224) channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.9 GO:0045296 cadherin binding(GO:0045296)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 1.8 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.2 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.3 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.2 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.1 GO:1990782 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.7 GO:0002039 p53 binding(GO:0002039)
0.0 0.4 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.2 GO:0003709 obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0 0.2 GO:0001614 purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.7 GO:0042393 histone binding(GO:0042393)
0.0 0.5 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 4.7 GO:0019904 protein domain specific binding(GO:0019904)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 3.6 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.2 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.2 GO:0051635 obsolete bacterial cell surface binding(GO:0051635)
0.0 0.2 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.3 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.3 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.4 GO:0008066 glutamate receptor activity(GO:0008066)
0.0 0.2 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.0 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 0.8 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.0 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.0 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.2 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.1 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.6 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.1 12.3 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.1 2.3 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.7 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.8 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.4 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.0 0.4 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.7 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.7 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.2 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.3 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.7 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.2 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.2 SIG_CHEMOTAXIS Genes related to chemotaxis