Motif ID: GAGGUAG

Z-value: 1.796


Mature miRNA associated with seed GAGGUAG:

NamemiRBase Accession
hsa-let-7a-5p MIMAT0000062
hsa-let-7b-5p MIMAT0000063
hsa-let-7c-5p MIMAT0000064
hsa-let-7d-5p MIMAT0000065
hsa-let-7e-5p MIMAT0000066
hsa-let-7f-5p MIMAT0000067
hsa-let-7g-5p MIMAT0000414
hsa-let-7i-5p MIMAT0000415
hsa-miR-4458 MIMAT0018980
hsa-miR-4500 MIMAT0019036
hsa-miR-98-5p MIMAT0000096



Activity profile for motif GAGGUAG.

activity profile for motif GAGGUAG


Sorted Z-values histogram for motif GAGGUAG

Sorted Z-values for motif GAGGUAG



Network of associatons between targets according to the STRING database.



First level regulatory network of GAGGUAG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_38721711 2.657 ENST00000578085.1
ENST00000246657.2
CCR7

chemokine (C-C motif) receptor 7

chr2_+_170590321 2.347 ENST00000392647.2
KLHL23
kelch-like family member 23
chr1_-_92351769 2.312 ENST00000212355.4
TGFBR3
transforming growth factor, beta receptor III
chr6_-_90121938 2.180 ENST00000369415.4
RRAGD
Ras-related GTP binding D
chr2_-_27435125 2.061 ENST00000414408.1
ENST00000310574.3
SLC5A6

solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6

chr8_+_56014949 2.021 ENST00000327381.6
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr16_-_89007491 1.954 ENST00000327483.5
ENST00000564416.1
CBFA2T3

core-binding factor, runt domain, alpha subunit 2; translocated to, 3

chr19_+_926000 1.844 ENST00000263620.3
ARID3A
AT rich interactive domain 3A (BRIGHT-like)
chr20_+_37434329 1.728 ENST00000299824.1
ENST00000373331.2
PPP1R16B

protein phosphatase 1, regulatory subunit 16B

chr15_-_45670924 1.668 ENST00000396659.3
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr8_+_61591337 1.664 ENST00000423902.2
CHD7
chromodomain helicase DNA binding protein 7
chr6_-_99797522 1.654 ENST00000389677.5
FAXC
failed axon connections homolog (Drosophila)
chrX_+_152907913 1.584 ENST00000370167.4
DUSP9
dual specificity phosphatase 9
chr2_+_65216462 1.491 ENST00000234256.3
SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr1_-_225615599 1.479 ENST00000421383.1
ENST00000272163.4
LBR

lamin B receptor

chr19_-_7293942 1.477 ENST00000341500.5
ENST00000302850.5
INSR

insulin receptor

chr1_+_213123915 1.466 ENST00000366968.4
ENST00000490792.1
VASH2

vasohibin 2

chr8_+_86089460 1.434 ENST00000418930.2
E2F5
E2F transcription factor 5, p130-binding
chr18_-_74207146 1.429 ENST00000443185.2
ZNF516
zinc finger protein 516
chr2_-_97535708 1.405 ENST00000305476.5
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr22_+_21771656 1.377 ENST00000407464.2
HIC2
hypermethylated in cancer 2
chr20_+_61448376 1.375 ENST00000343916.3
COL9A3
collagen, type IX, alpha 3
chr17_+_53342311 1.368 ENST00000226067.5
HLF
hepatic leukemia factor
chr8_+_126442563 1.358 ENST00000311922.3
TRIB1
tribbles pseudokinase 1
chr6_+_138188551 1.343 ENST00000237289.4
ENST00000433680.1
TNFAIP3

tumor necrosis factor, alpha-induced protein 3

chr7_-_23510086 1.310 ENST00000258729.3
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr5_-_175964366 1.294 ENST00000274811.4
RNF44
ring finger protein 44
chr12_-_49393092 1.274 ENST00000421952.2
DDN
dendrin
chr18_+_55102917 1.251 ENST00000491143.2
ONECUT2
one cut homeobox 2
chr3_-_47823298 1.238 ENST00000254480.5
SMARCC1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr1_+_15943995 1.225 ENST00000480945.1
DDI2
DNA-damage inducible 1 homolog 2 (S. cerevisiae)
chr9_-_36400213 1.217 ENST00000259605.6
ENST00000353739.4
RNF38

ring finger protein 38

chr15_+_74833518 1.208 ENST00000346246.5
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr9_+_90112741 1.198 ENST00000469640.2
DAPK1
death-associated protein kinase 1
chr2_-_24149977 1.184 ENST00000238789.5
ATAD2B
ATPase family, AAA domain containing 2B
chr4_+_128554081 1.178 ENST00000335251.6
ENST00000296461.5
INTU

inturned planar cell polarity protein

chr22_+_25960786 1.156 ENST00000324198.6
ADRBK2
adrenergic, beta, receptor kinase 2
chr8_+_81397876 1.139 ENST00000430430.1
ZBTB10
zinc finger and BTB domain containing 10
chr1_+_150122034 1.136 ENST00000025469.6
ENST00000369124.4
PLEKHO1

pleckstrin homology domain containing, family O member 1

chr3_+_38495333 1.130 ENST00000352511.4
ACVR2B
activin A receptor, type IIB
chr2_+_11674213 1.130 ENST00000381486.2
GREB1
growth regulation by estrogen in breast cancer 1
chr6_+_106546808 1.115 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr17_-_34625719 1.114 ENST00000422211.2
ENST00000542124.1
CCL3L1

chemokine (C-C motif) ligand 3-like 1

chr4_-_23891693 1.099 ENST00000264867.2
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr15_-_90645679 1.077 ENST00000539790.1
ENST00000559482.1
ENST00000330062.3
IDH2


isocitrate dehydrogenase 2 (NADP+), mitochondrial


chr12_-_102874416 1.066 ENST00000392904.1
ENST00000337514.6
IGF1

insulin-like growth factor 1 (somatomedin C)

chr15_+_75498355 1.061 ENST00000567617.1
C15orf39
chromosome 15 open reading frame 39
chr3_-_121553830 1.045 ENST00000498104.1
ENST00000460108.1
ENST00000349820.6
ENST00000462442.1
ENST00000310864.6
IQCB1




IQ motif containing B1




chr17_-_34417479 1.022 ENST00000225245.5
CCL3
chemokine (C-C motif) ligand 3
chrX_-_33146477 1.017 ENST00000378677.2
DMD
dystrophin
chr2_+_75061108 1.014 ENST00000290573.2
HK2
hexokinase 2
chr7_+_94285637 1.010 ENST00000482108.1
ENST00000488574.1
PEG10

paternally expressed 10

chr9_+_131174024 0.946 ENST00000420034.1
ENST00000372842.1
CERCAM

cerebral endothelial cell adhesion molecule

chr15_-_38856836 0.938 ENST00000450598.2
ENST00000559830.1
ENST00000558164.1
ENST00000310803.5
RASGRP1



RAS guanyl releasing protein 1 (calcium and DAG-regulated)



chr17_-_34524157 0.928 ENST00000378354.4
ENST00000394484.1
CCL3L3

chemokine (C-C motif) ligand 3-like 3

chr1_-_200992827 0.917 ENST00000332129.2
ENST00000422435.2
KIF21B

kinesin family member 21B

chr7_-_71801980 0.917 ENST00000329008.5
CALN1
calneuron 1
chr12_+_94542459 0.909 ENST00000258526.4
PLXNC1
plexin C1
chr1_-_212004090 0.902 ENST00000366997.4
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr1_-_182573514 0.856 ENST00000367558.5
RGS16
regulator of G-protein signaling 16
chr3_-_53080047 0.855 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
SFMBT1



Scm-like with four mbt domains 1



chr20_+_55966444 0.850 ENST00000356208.5
ENST00000440234.2
RBM38

RNA binding motif protein 38

chr1_-_247094628 0.850 ENST00000366508.1
ENST00000326225.3
ENST00000391829.2
AHCTF1


AT hook containing transcription factor 1


chr15_+_41952591 0.847 ENST00000566718.1
ENST00000219905.7
ENST00000389936.4
ENST00000545763.1
MGA



MGA, MAX dimerization protein



chr8_-_82024290 0.845 ENST00000220597.4
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr2_+_10262442 0.843 ENST00000360566.2
RRM2
ribonucleotide reductase M2
chr5_+_32585605 0.836 ENST00000265073.4
ENST00000515355.1
ENST00000502897.1
ENST00000510442.1
SUB1



SUB1 homolog (S. cerevisiae)



chr11_+_123396528 0.832 ENST00000322282.7
ENST00000529750.1
GRAMD1B

GRAM domain containing 1B

chr2_+_113239710 0.830 ENST00000233336.6
TTL
tubulin tyrosine ligase
chr6_-_32157947 0.806 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr11_+_58939965 0.783 ENST00000227451.3
DTX4
deltex homolog 4 (Drosophila)
chr7_+_7606497 0.776 ENST00000340080.4
ENST00000405785.1
ENST00000433635.1
MIOS


missing oocyte, meiosis regulator, homolog (Drosophila)


chr1_+_32930647 0.770 ENST00000609129.1
ZBTB8B
zinc finger and BTB domain containing 8B
chr11_-_86666427 0.767 ENST00000531380.1
FZD4
frizzled family receptor 4
chr5_+_65440032 0.766 ENST00000334121.6
SREK1
splicing regulatory glutamine/lysine-rich protein 1
chr4_+_75858290 0.756 ENST00000513238.1
PARM1
prostate androgen-regulated mucin-like protein 1
chr20_-_30795511 0.751 ENST00000246229.4
PLAGL2
pleiomorphic adenoma gene-like 2
chr12_-_76478686 0.747 ENST00000261182.8
NAP1L1
nucleosome assembly protein 1-like 1
chr10_-_94003003 0.744 ENST00000412050.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr17_+_64961026 0.736 ENST00000262138.3
CACNG4
calcium channel, voltage-dependent, gamma subunit 4
chr15_-_37390482 0.732 ENST00000559085.1
ENST00000397624.3
MEIS2

Meis homeobox 2

chr11_-_66115032 0.732 ENST00000311181.4
B3GNT1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr8_-_101571964 0.731 ENST00000520552.1
ENST00000521345.1
ENST00000523000.1
ENST00000335659.3
ENST00000358990.3
ENST00000519597.1
ANKRD46





ankyrin repeat domain 46





chr4_+_17616253 0.714 ENST00000237380.7
MED28
mediator complex subunit 28
chr1_+_38158090 0.706 ENST00000373055.1
ENST00000327331.2
CDCA8

cell division cycle associated 8

chr17_-_9929581 0.702 ENST00000437099.2
ENST00000396115.2
GAS7

growth arrest-specific 7

chr13_-_95248511 0.697 ENST00000261296.5
TGDS
TDP-glucose 4,6-dehydratase
chr3_-_49459878 0.697 ENST00000546031.1
ENST00000458307.2
ENST00000430521.1
AMT


aminomethyltransferase


chr22_+_39898325 0.696 ENST00000325301.2
ENST00000404569.1
MIEF1

mitochondrial elongation factor 1

chr17_-_61777459 0.694 ENST00000578993.1
ENST00000583211.1
ENST00000259006.3
LIMD2


LIM domain containing 2


chr11_+_20620946 0.691 ENST00000525748.1
SLC6A5
solute carrier family 6 (neurotransmitter transporter), member 5
chr4_+_186064395 0.690 ENST00000281456.6
SLC25A4
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr1_+_12227035 0.690 ENST00000376259.3
ENST00000536782.1
TNFRSF1B

tumor necrosis factor receptor superfamily, member 1B

chrX_+_37545012 0.688 ENST00000378616.3
XK
X-linked Kx blood group (McLeod syndrome)
chr1_+_36348790 0.685 ENST00000373204.4
AGO1
argonaute RISC catalytic component 1
chr1_+_60280458 0.673 ENST00000455990.1
ENST00000371208.3
HOOK1

hook microtubule-tethering protein 1

chr21_+_30671189 0.673 ENST00000286800.3
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chrX_-_20284958 0.671 ENST00000379565.3
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr19_+_531713 0.667 ENST00000215574.4
CDC34
cell division cycle 34
chr8_+_22102626 0.667 ENST00000519237.1
ENST00000397802.4
POLR3D

polymerase (RNA) III (DNA directed) polypeptide D, 44kDa

chrX_-_129244655 0.662 ENST00000335997.7
ELF4
E74-like factor 4 (ets domain transcription factor)
chr4_-_100867864 0.661 ENST00000442697.2
DNAJB14
DnaJ (Hsp40) homolog, subfamily B, member 14
chr1_-_39339777 0.654 ENST00000397572.2
MYCBP
MYC binding protein
chr8_-_144623595 0.653 ENST00000262577.5
ZC3H3
zinc finger CCCH-type containing 3
chr11_+_119076745 0.653 ENST00000264033.4
CBL
Cbl proto-oncogene, E3 ubiquitin protein ligase
chr5_+_65018017 0.641 ENST00000380985.5
ENST00000502464.1
NLN

neurolysin (metallopeptidase M3 family)

chr18_+_55711575 0.630 ENST00000356462.6
ENST00000400345.3
ENST00000589054.1
ENST00000256832.7
NEDD4L



neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase



chr2_-_152684977 0.624 ENST00000428992.2
ENST00000295087.8
ARL5A

ADP-ribosylation factor-like 5A

chrX_+_108780062 0.615 ENST00000372106.1
NXT2
nuclear transport factor 2-like export factor 2
chr22_+_42229100 0.611 ENST00000361204.4
SREBF2
sterol regulatory element binding transcription factor 2
chr10_+_14920843 0.602 ENST00000433779.1
ENST00000378325.3
ENST00000354919.6
ENST00000313519.5
ENST00000420416.1
SUV39H2




suppressor of variegation 3-9 homolog 2 (Drosophila)




chr2_+_109335929 0.600 ENST00000283195.6
RANBP2
RAN binding protein 2
chr2_+_177053307 0.598 ENST00000331462.4
HOXD1
homeobox D1
chr10_+_88516396 0.596 ENST00000372037.3
BMPR1A
bone morphogenetic protein receptor, type IA
chr20_-_62601218 0.594 ENST00000369888.1
ZNF512B
zinc finger protein 512B
chr17_+_29718642 0.587 ENST00000325874.8
RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr14_+_74111578 0.578 ENST00000554113.1
ENST00000555631.2
ENST00000553645.2
ENST00000311089.3
ENST00000555919.3
ENST00000554339.1
ENST00000554871.1
DNAL1






dynein, axonemal, light chain 1






chr1_-_207224307 0.569 ENST00000315927.4
YOD1
YOD1 deubiquitinase
chr17_-_65241281 0.560 ENST00000358691.5
ENST00000580168.1
HELZ

helicase with zinc finger

chr2_-_242212227 0.552 ENST00000427007.1
ENST00000458564.1
ENST00000452065.1
ENST00000427183.2
ENST00000426343.1
ENST00000422080.1
ENST00000449504.1
ENST00000449864.1
ENST00000391975.1
HDLBP








high density lipoprotein binding protein








chr15_+_90544532 0.549 ENST00000268154.4
ZNF710
zinc finger protein 710
chr1_-_55680762 0.543 ENST00000407756.1
ENST00000294383.6
USP24

ubiquitin specific peptidase 24

chr7_-_44924939 0.542 ENST00000395699.2
PURB
purine-rich element binding protein B
chr19_+_4007644 0.538 ENST00000262971.2
PIAS4
protein inhibitor of activated STAT, 4
chr12_-_111021110 0.538 ENST00000354300.3
PPTC7
PTC7 protein phosphatase homolog (S. cerevisiae)
chr9_-_77567743 0.537 ENST00000376854.5
C9orf40
chromosome 9 open reading frame 40
chr3_-_142166904 0.533 ENST00000264951.4
XRN1
5'-3' exoribonuclease 1
chr1_-_108507631 0.529 ENST00000527011.1
ENST00000370056.4
VAV3

vav 3 guanine nucleotide exchange factor

chr2_-_152955537 0.525 ENST00000201943.5
ENST00000539935.1
CACNB4

calcium channel, voltage-dependent, beta 4 subunit

chr17_-_55038375 0.523 ENST00000240316.4
COIL
coilin
chr1_+_89990431 0.520 ENST00000330947.2
ENST00000358200.4
LRRC8B

leucine rich repeat containing 8 family, member B

chr3_-_170303845 0.509 ENST00000231706.5
SLC7A14
solute carrier family 7, member 14
chr11_-_74109422 0.509 ENST00000298198.4
PGM2L1
phosphoglucomutase 2-like 1
chr8_+_98656336 0.506 ENST00000336273.3
MTDH
metadherin
chr11_-_62389449 0.505 ENST00000534026.1
B3GAT3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr15_-_51630772 0.504 ENST00000557858.1
ENST00000558328.1
ENST00000396404.4
ENST00000561075.1
ENST00000405011.2
ENST00000559980.1
ENST00000453807.2
ENST00000396402.1
CYP19A1







cytochrome P450, family 19, subfamily A, polypeptide 1







chr22_+_50624323 0.496 ENST00000380909.4
ENST00000303434.4
TRABD

TraB domain containing

chr8_-_127570603 0.496 ENST00000304916.3
FAM84B
family with sequence similarity 84, member B
chr10_-_70231639 0.494 ENST00000551118.2
ENST00000358410.3
ENST00000399180.2
ENST00000399179.2
DNA2



DNA replication helicase/nuclease 2



chr7_+_20370746 0.494 ENST00000222573.4
ITGB8
integrin, beta 8
chr3_+_121774202 0.493 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86



CD86 molecule



chr12_+_68042495 0.493 ENST00000344096.3
DYRK2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr19_+_6531010 0.491 ENST00000245817.3
TNFSF9
tumor necrosis factor (ligand) superfamily, member 9
chr5_+_180682720 0.489 ENST00000599439.1
AC008443.1
CDNA: FLJ23158 fis, clone LNG09623; Uncharacterized protein
chr5_-_37371278 0.486 ENST00000231498.3
NUP155
nucleoporin 155kDa
chr1_-_169863016 0.484 ENST00000367772.4
ENST00000367771.6
SCYL3

SCY1-like 3 (S. cerevisiae)

chr1_+_87380299 0.478 ENST00000370551.4
ENST00000370550.5
HS2ST1

heparan sulfate 2-O-sulfotransferase 1

chr2_+_85198216 0.470 ENST00000456682.1
ENST00000409785.4
KCMF1

potassium channel modulatory factor 1

chrX_-_110655391 0.467 ENST00000356915.2
ENST00000356220.3
DCX

doublecortin

chr19_+_50528971 0.460 ENST00000598809.1
ENST00000595661.1
ENST00000391821.2
ZNF473


zinc finger protein 473


chr10_-_52645416 0.458 ENST00000374001.2
ENST00000373997.3
ENST00000373995.3
ENST00000282641.2
ENST00000395495.1
ENST00000414883.1
A1CF





APOBEC1 complementation factor





chr1_-_204121013 0.444 ENST00000367201.3
ETNK2
ethanolamine kinase 2
chr16_+_447209 0.443 ENST00000382940.4
ENST00000219479.2
NME4

NME/NM23 nucleoside diphosphate kinase 4

chr6_-_86352642 0.437 ENST00000355238.6
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr15_+_52311398 0.436 ENST00000261845.5
MAPK6
mitogen-activated protein kinase 6
chr7_+_120628731 0.432 ENST00000310396.5
CPED1
cadherin-like and PC-esterase domain containing 1
chr21_+_45079409 0.429 ENST00000340648.4
RRP1B
ribosomal RNA processing 1B
chr15_+_89164520 0.427 ENST00000332810.3
AEN
apoptosis enhancing nuclease
chr12_-_6716534 0.425 ENST00000544484.1
ENST00000309577.6
ENST00000357008.2
CHD4


chromodomain helicase DNA binding protein 4


chr10_+_21823079 0.423 ENST00000377100.3
ENST00000377072.3
ENST00000446906.2
MLLT10


myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10


chr14_-_53162361 0.423 ENST00000395686.3
ERO1L
ERO1-like (S. cerevisiae)
chr11_-_10590238 0.420 ENST00000256178.3
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr11_+_111945011 0.419 ENST00000532163.1
ENST00000280352.9
ENST00000530104.1
ENST00000526879.1
ENST00000393047.3
ENST00000525785.1
C11orf57





chromosome 11 open reading frame 57





chr11_-_78052923 0.418 ENST00000340149.2
GAB2
GRB2-associated binding protein 2
chr1_+_203274639 0.411 ENST00000290551.4
BTG2
BTG family, member 2
chr2_+_219575543 0.408 ENST00000457313.1
ENST00000415717.1
ENST00000392102.1
TTLL4


tubulin tyrosine ligase-like family, member 4


chr6_+_292459 0.406 ENST00000419235.2
ENST00000605035.1
ENST00000605863.1
DUSP22


dual specificity phosphatase 22


chr5_-_132948216 0.406 ENST00000265342.7
FSTL4
follistatin-like 4
chr7_+_108210012 0.404 ENST00000249356.3
DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr2_+_99953816 0.404 ENST00000289371.6
EIF5B
eukaryotic translation initiation factor 5B
chr12_+_74931551 0.401 ENST00000519948.2
ATXN7L3B
ataxin 7-like 3B
chr14_+_100150622 0.401 ENST00000261835.3
CYP46A1
cytochrome P450, family 46, subfamily A, polypeptide 1
chr14_+_100705322 0.400 ENST00000262238.4
YY1
YY1 transcription factor
chr5_+_61602055 0.397 ENST00000381103.2
KIF2A
kinesin heavy chain member 2A
chr3_+_184097836 0.395 ENST00000204604.1
ENST00000310236.3
CHRD

chordin

chr2_-_128615681 0.395 ENST00000409955.1
ENST00000272645.4
POLR2D

polymerase (RNA) II (DNA directed) polypeptide D

chr9_-_111696340 0.390 ENST00000374647.5
IKBKAP
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
chr3_-_185216766 0.388 ENST00000296254.3
TMEM41A
transmembrane protein 41A
chr1_-_179846928 0.385 ENST00000367612.3
ENST00000609928.1
TOR1AIP2

torsin A interacting protein 2

chr4_-_174451370 0.384 ENST00000359562.4
HAND2
heart and neural crest derivatives expressed 2
chr1_+_161129254 0.383 ENST00000368002.3
ENST00000289865.8
ENST00000479344.1
ENST00000368001.1
USP21



ubiquitin specific peptidase 21



chr19_-_44100275 0.381 ENST00000422989.1
ENST00000598324.1
IRGQ

immunity-related GTPase family, Q

chr8_+_28351707 0.375 ENST00000537916.1
ENST00000523546.1
ENST00000240093.3
FZD3


frizzled family receptor 3


chr1_-_146644122 0.373 ENST00000254101.3
PRKAB2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr1_+_167190066 0.371 ENST00000367866.2
ENST00000429375.2
ENST00000452019.1
ENST00000420254.3
ENST00000541643.3
POU2F1




POU class 2 homeobox 1




chr12_-_42538657 0.370 ENST00000398675.3
GXYLT1
glucoside xylosyltransferase 1
chr6_-_97285336 0.365 ENST00000229955.3
ENST00000417980.1
GPR63

G protein-coupled receptor 63

chr15_-_83316254 0.362 ENST00000567678.1
ENST00000450751.2
CPEB1

cytoplasmic polyadenylation element binding protein 1

chr20_-_48532019 0.362 ENST00000289431.5
SPATA2
spermatogenesis associated 2
chr13_-_27745936 0.362 ENST00000282344.6
USP12
ubiquitin specific peptidase 12
chr3_+_183873098 0.359 ENST00000313143.3
DVL3
dishevelled segment polarity protein 3
chr5_+_56111361 0.356 ENST00000399503.3
MAP3K1
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr12_-_25102252 0.347 ENST00000261192.7
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chrX_-_48755030 0.346 ENST00000490755.2
ENST00000465150.2
ENST00000495490.2
TIMM17B


translocase of inner mitochondrial membrane 17 homolog B (yeast)


chr1_+_20208870 0.342 ENST00000375120.3
OTUD3
OTU domain containing 3
chrX_-_24690771 0.334 ENST00000379145.1
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr16_-_47007545 0.333 ENST00000317089.5
DNAJA2
DnaJ (Hsp40) homolog, subfamily A, member 2
chr17_-_6459768 0.332 ENST00000421306.3
PITPNM3
PITPNM family member 3
chr3_-_171178157 0.325 ENST00000465393.1
ENST00000436636.2
ENST00000369326.5
ENST00000538048.1
ENST00000341852.6
TNIK




TRAF2 and NCK interacting kinase




chr11_+_76571911 0.324 ENST00000534206.1
ENST00000532485.1
ENST00000526597.1
ENST00000533873.1
ENST00000538157.1
ACER3




alkaline ceramidase 3





Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0060318 definitive erythrocyte differentiation(GO:0060318)
0.7 2.1 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.5 1.5 GO:0032328 alanine transport(GO:0032328)
0.5 1.5 GO:0060267 transformation of host cell by virus(GO:0019087) positive regulation of respiratory burst(GO:0060267)
0.5 2.7 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.4 1.1 GO:0006097 glyoxylate cycle(GO:0006097)
0.3 1.0 GO:0048496 maintenance of organ identity(GO:0048496)
0.3 1.3 GO:0048935 peripheral nervous system neuron development(GO:0048935)
0.3 0.8 GO:0046931 pore complex assembly(GO:0046931)
0.3 0.8 GO:0061298 progesterone secretion(GO:0042701) retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.2 0.9 GO:0009103 lipopolysaccharide biosynthetic process(GO:0009103)
0.2 0.7 GO:0060547 negative regulation of necrotic cell death(GO:0060547)
0.2 0.8 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.2 0.6 GO:0021754 facial nucleus development(GO:0021754)
0.2 1.2 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.2 1.1 GO:0009441 glycolate metabolic process(GO:0009441)
0.2 0.8 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.2 0.5 GO:0006273 lagging strand elongation(GO:0006273)
0.2 0.5 GO:0042097 lymphotoxin A production(GO:0032641) interleukin-4 biosynthetic process(GO:0042097) lymphotoxin A biosynthetic process(GO:0042109) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.2 2.0 GO:0007512 adult heart development(GO:0007512)
0.2 2.5 GO:0071230 cellular response to amino acid stimulus(GO:0071230)
0.2 1.7 GO:0006600 creatine metabolic process(GO:0006600)
0.2 0.5 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.3 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1 0.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.5 GO:0071025 RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.1 1.7 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 0.4 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.1 0.4 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.1 0.4 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.6 GO:0032933 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.7 GO:0000089 mitotic metaphase(GO:0000089)
0.1 0.7 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.3 GO:0046520 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.1 0.5 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 0.1 GO:0071635 negative regulation of transforming growth factor beta production(GO:0071635)
0.1 0.5 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.1 0.5 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 0.4 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.3 GO:0002677 negative regulation of chronic inflammatory response(GO:0002677) regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.1 0.6 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 0.8 GO:0006546 glycine catabolic process(GO:0006546)
0.1 0.3 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 0.5 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.8 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.1 0.5 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.7 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.1 0.5 GO:0060676 ureteric bud formation(GO:0060676) mesonephric tubule formation(GO:0072172)
0.1 0.5 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.1 0.3 GO:0046778 modification by virus of host mRNA processing(GO:0046778)
0.1 0.7 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.2 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.1 0.2 GO:0003207 cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211) cardiac left ventricle formation(GO:0003218)
0.1 0.4 GO:0050685 positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.1 0.7 GO:0001866 NK T cell proliferation(GO:0001866)
0.1 0.2 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307) DNA dealkylation(GO:0035510)
0.1 0.6 GO:0046051 GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.1 0.4 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 2.0 GO:0030851 granulocyte differentiation(GO:0030851)
0.1 0.3 GO:0032455 nerve growth factor processing(GO:0032455)
0.1 0.4 GO:0003148 outflow tract septum morphogenesis(GO:0003148)
0.1 1.1 GO:0001893 maternal placenta development(GO:0001893)
0.1 0.3 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.1 0.3 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082)
0.1 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.8 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.5 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.1 0.6 GO:0051567 histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.0 0.1 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.0 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.2 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.0 0.4 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.1 GO:0070544 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188) histone H3-K36 demethylation(GO:0070544)
0.0 0.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.3 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.2 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0 0.1 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.0 0.4 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.3 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 1.0 GO:0045069 regulation of viral genome replication(GO:0045069)
0.0 0.4 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.2 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.5 GO:0001573 ganglioside metabolic process(GO:0001573) placenta blood vessel development(GO:0060674)
0.0 0.6 GO:1902603 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0 0.1 GO:0010834 obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0 0.7 GO:0006386 transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0 0.6 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 1.1 GO:0051925 obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0 0.5 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.1 GO:0010586 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.2 GO:0046898 response to cycloheximide(GO:0046898)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.7 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260)
0.0 1.5 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.0 0.3 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.7 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0010523 negative regulation of calcium ion transport into cytosol(GO:0010523)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.3 GO:0034644 cellular response to UV(GO:0034644)
0.0 0.1 GO:0051531 NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0 0.0 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.5 GO:0006023 aminoglycan biosynthetic process(GO:0006023)
0.0 0.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.2 GO:0001660 fever generation(GO:0001660)
0.0 0.9 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.1 GO:0010225 response to UV-C(GO:0010225)
0.0 0.3 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.6 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.3 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 1.6 GO:0070304 positive regulation of stress-activated MAPK cascade(GO:0032874) positive regulation of stress-activated protein kinase signaling cascade(GO:0070304)
0.0 0.1 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.9 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.3 GO:2000273 positive regulation of receptor activity(GO:2000273)
0.0 0.4 GO:0016578 histone deubiquitination(GO:0016578)
0.0 1.5 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.2 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390) positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.8 GO:0050868 negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0 0.3 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.4 GO:0036503 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) ERAD pathway(GO:0036503)
0.0 1.1 GO:0007254 JNK cascade(GO:0007254)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.2 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.4 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.2 GO:0040023 establishment of nucleus localization(GO:0040023)
0.0 0.3 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 2.3 GO:0050658 nucleic acid transport(GO:0050657) RNA transport(GO:0050658) establishment of RNA localization(GO:0051236)
0.0 0.2 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.4 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 1.0 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.3 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.2 GO:0050812 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.1 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.2 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.2 GO:0009755 hormone-mediated signaling pathway(GO:0009755)
0.0 0.1 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.3 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280) negative regulation of lyase activity(GO:0051350)
0.0 0.2 GO:0034453 microtubule nucleation(GO:0007020) microtubule anchoring(GO:0034453)
0.0 0.1 GO:0015780 nucleotide-sugar transport(GO:0015780)
0.0 1.7 GO:0007204 positive regulation of cytosolic calcium ion concentration(GO:0007204)
0.0 0.4 GO:0016579 protein deubiquitination(GO:0016579)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.4 1.6 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.4 1.5 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.3 1.5 GO:0005899 insulin receptor complex(GO:0005899)
0.3 1.4 GO:0005594 collagen type IX trimer(GO:0005594)
0.2 1.0 GO:0016600 flotillin complex(GO:0016600)
0.2 1.2 GO:0001741 XY body(GO:0001741)
0.2 0.7 GO:0070695 FHF complex(GO:0070695)
0.2 0.5 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 0.7 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 1.1 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 1.0 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 0.3 GO:0035189 Rb-E2F complex(GO:0035189)
0.1 0.5 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 0.7 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.1 1.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.5 GO:0042575 DNA polymerase complex(GO:0042575)
0.1 0.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.2 GO:0031213 RSF complex(GO:0031213)
0.1 2.1 GO:0031526 brush border membrane(GO:0031526)
0.1 0.3 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 0.5 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.8 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0009279 cell outer membrane(GO:0009279)
0.0 2.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 1.0 GO:0043034 costamere(GO:0043034)
0.0 0.3 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.3 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 1.1 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.2 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.6 GO:0090568 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 0.3 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.5 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.2 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.5 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 1.1 GO:0015030 Cajal body(GO:0015030)
0.0 0.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.7 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.5 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.0 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032) PAS complex(GO:0070772)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.4 GO:0005789 endoplasmic reticulum membrane(GO:0005789) nuclear outer membrane-endoplasmic reticulum membrane network(GO:0042175)
0.0 0.1 GO:0008278 cohesin complex(GO:0008278)
0.0 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.4 GO:0055037 recycling endosome(GO:0055037)
0.0 0.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.9 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.6 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.3 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 1.4 GO:0045111 intermediate filament cytoskeleton(GO:0045111)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.5 1.5 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.5 1.5 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.4 0.4 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.4 1.5 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.4 1.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.3 0.8 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2 0.7 GO:0015217 purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) ATP:ADP antiporter activity(GO:0005471) ADP transmembrane transporter activity(GO:0015217)
0.2 1.7 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.2 0.8 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.2 1.4 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.2 1.9 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.2 0.5 GO:0032422 translation repressor activity, nucleic acid binding(GO:0000900) purine-rich negative regulatory element binding(GO:0032422)
0.2 2.7 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.2 0.7 GO:0015187 glycine transmembrane transporter activity(GO:0015187) glycine:sodium symporter activity(GO:0015375)
0.2 1.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.2 0.5 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.2 0.6 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.1 1.0 GO:0004340 glucokinase activity(GO:0004340)
0.1 1.2 GO:0004835 tubulin-tyrosine ligase activity(GO:0004835)
0.1 0.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.6 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 0.6 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.8 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 0.3 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 1.0 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.5 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.1 0.5 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.3 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.6 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.3 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 2.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.5 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.4 GO:0045545 syndecan binding(GO:0045545)
0.1 0.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.4 GO:0004103 choline kinase activity(GO:0004103)
0.1 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 1.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.6 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.1 2.0 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.1 0.8 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.1 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.2 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.1 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.5 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.9 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.2 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.0 1.2 GO:0042056 chemoattractant activity(GO:0042056)
0.0 1.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.4 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 1.1 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.2 GO:0004741 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0033765 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.4 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.7 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.3 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.4 GO:0070888 E-box binding(GO:0070888)
0.0 1.1 GO:0008009 chemokine activity(GO:0008009)
0.0 0.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 2.0 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 1.1 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.3 GO:0005123 death receptor binding(GO:0005123)
0.0 0.2 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.4 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 1.6 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.5 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.2 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.0 GO:0070700 transmembrane receptor protein serine/threonine kinase binding(GO:0070696) BMP receptor binding(GO:0070700)
0.0 3.6 GO:0003682 chromatin binding(GO:0003682)
0.0 0.9 GO:0004221 obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0 0.5 GO:0019239 deaminase activity(GO:0019239)
0.0 0.7 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0015925 galactosidase activity(GO:0015925)
0.0 1.1 GO:0008017 microtubule binding(GO:0008017)
0.0 0.7 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 2.1 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.2 GO:0003924 GTPase activity(GO:0003924)
0.0 0.1 GO:0051378 serotonin binding(GO:0051378)
0.0 0.5 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 2.6 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.1 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.7 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.3 GO:0000049 tRNA binding(GO:0000049)
0.0 10.4 GO:0003700 transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0030280 structural constituent of epidermis(GO:0030280)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.9 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.6 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.2 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.6 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.6 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.0 0.7 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.2 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.0 0.1 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway