Motif ID: GATA1_GATA4

Z-value: 2.854

Transcription factors associated with GATA1_GATA4:

Gene SymbolEntrez IDGene Name
GATA1 ENSG00000102145.9 GATA1
GATA4 ENSG00000136574.13 GATA4






Network of associatons between targets according to the STRING database.



First level regulatory network of GATA1_GATA4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_202686 7.933 ENST00000252951.2
HBZ
hemoglobin, zeta
chr19_-_13213662 6.710 ENST00000264824.4
LYL1
lymphoblastic leukemia derived sequence 1
chr12_-_54689532 6.305 ENST00000540264.2
ENST00000312156.4
NFE2

nuclear factor, erythroid 2

chr17_-_62084241 5.183 ENST00000449662.2
ICAM2
intercellular adhesion molecule 2
chrX_-_78622805 4.277 ENST00000373298.2
ITM2A
integral membrane protein 2A
chr19_+_10397621 4.115 ENST00000380770.3
ICAM4
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr19_+_10397648 4.059 ENST00000340992.4
ENST00000393717.2
ICAM4

intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)

chr19_-_55669093 3.706 ENST00000344887.5
TNNI3
troponin I type 3 (cardiac)
chr21_-_15918618 3.425 ENST00000400564.1
ENST00000400566.1
SAMSN1

SAM domain, SH3 domain and nuclear localization signals 1

chr11_-_5271122 3.418 ENST00000330597.3
HBG1
hemoglobin, gamma A
chr19_-_12997995 3.390 ENST00000264834.4
KLF1
Kruppel-like factor 1 (erythroid)
chr1_+_25598989 3.319 ENST00000454452.2
RHD
Rh blood group, D antigen
chr11_+_118958689 3.236 ENST00000535253.1
ENST00000392841.1
HMBS

hydroxymethylbilane synthase

chr7_-_100239132 3.188 ENST00000223051.3
ENST00000431692.1
TFR2

transferrin receptor 2

chr10_+_70847852 3.179 ENST00000242465.3
SRGN
serglycin
chr7_-_150652924 3.167 ENST00000330883.4
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr5_-_141061759 2.561 ENST00000508305.1
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr5_-_141061777 2.438 ENST00000239440.4
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr12_-_6233828 2.387 ENST00000572068.1
ENST00000261405.5
VWF

von Willebrand factor

chr1_+_161136180 2.241 ENST00000352210.5
ENST00000367999.4
ENST00000544598.1
ENST00000535223.1
ENST00000432542.2
PPOX




protoporphyrinogen oxidase




chr1_-_225616515 2.235 ENST00000338179.2
ENST00000425080.1
LBR

lamin B receptor

chr1_+_25598872 2.233 ENST00000328664.4
RHD
Rh blood group, D antigen
chr7_-_50860565 2.196 ENST00000403097.1
GRB10
growth factor receptor-bound protein 10
chr4_-_144940477 2.122 ENST00000513128.1
ENST00000429670.2
ENST00000502664.1
GYPB


glycophorin B (MNS blood group)


chr15_-_58306295 2.115 ENST00000559517.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr6_-_31846744 2.103 ENST00000414427.1
ENST00000229729.6
ENST00000375562.4
SLC44A4


solute carrier family 44, member 4


chr1_+_25599018 2.094 ENST00000417538.2
ENST00000357542.4
ENST00000568195.1
ENST00000342055.5
ENST00000423810.2
RHD




Rh blood group, D antigen




chr4_-_103266355 2.075 ENST00000424970.2
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr9_+_139557360 2.050 ENST00000308874.7
ENST00000406555.3
ENST00000492862.2
EGFL7


EGF-like-domain, multiple 7


chr1_-_25747283 2.027 ENST00000346452.4
ENST00000340849.4
ENST00000349438.4
ENST00000294413.7
ENST00000413854.1
ENST00000455194.1
ENST00000243186.6
ENST00000425135.1
RHCE







Rh blood group, CcEe antigens







chr8_+_21823726 2.026 ENST00000433566.4
XPO7
exportin 7
chr1_-_225615599 1.972 ENST00000421383.1
ENST00000272163.4
LBR

lamin B receptor

chr3_+_169629354 1.890 ENST00000428432.2
ENST00000335556.3
SAMD7

sterile alpha motif domain containing 7

chr3_-_98312548 1.794 ENST00000264193.2
CPOX
coproporphyrinogen oxidase
chr11_+_128563652 1.729 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr1_+_198608146 1.712 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
PTPRC









protein tyrosine phosphatase, receptor type, C









chr11_-_5255861 1.697 ENST00000380299.3
HBD
hemoglobin, delta
chr8_+_56014949 1.686 ENST00000327381.6
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr12_-_71148413 1.653 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
PTPRR


protein tyrosine phosphatase, receptor type, R


chr12_-_71148357 1.644 ENST00000378778.1
PTPRR
protein tyrosine phosphatase, receptor type, R
chr2_+_102928009 1.625 ENST00000404917.2
ENST00000447231.1
IL1RL1

interleukin 1 receptor-like 1

chr8_-_38008783 1.598 ENST00000276449.4
STAR
steroidogenic acute regulatory protein
chr6_+_12290586 1.578 ENST00000379375.5
EDN1
endothelin 1
chrX_+_65382433 1.570 ENST00000374727.3
HEPH
hephaestin
chr17_-_47841485 1.566 ENST00000506156.1
ENST00000240364.2
FAM117A

family with sequence similarity 117, member A

chr1_-_155270770 1.563 ENST00000392414.3
PKLR
pyruvate kinase, liver and RBC
chr2_+_201994042 1.544 ENST00000417748.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr17_+_37824217 1.538 ENST00000394246.1
PNMT
phenylethanolamine N-methyltransferase
chrX_-_55057403 1.537 ENST00000396198.3
ENST00000335854.4
ENST00000455688.1
ENST00000330807.5
ALAS2



aminolevulinate, delta-, synthase 2



chr4_-_144826682 1.533 ENST00000358615.4
ENST00000437468.2
GYPE

glycophorin E (MNS blood group)

chr3_-_119379719 1.461 ENST00000493094.1
POPDC2
popeye domain containing 2
chr3_+_151986709 1.429 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
MBNL1



muscleblind-like splicing regulator 1



chr11_-_57158109 1.421 ENST00000525955.1
ENST00000533605.1
ENST00000311862.5
PRG2


proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)


chr10_+_28822636 1.399 ENST00000442148.1
ENST00000448193.1
WAC

WW domain containing adaptor with coiled-coil

chr4_-_145061788 1.381 ENST00000512064.1
ENST00000512789.1
ENST00000504786.1
ENST00000503627.1
ENST00000535709.1
ENST00000324022.10
ENST00000360771.4
ENST00000283126.7
GYPA






GYPB
glycophorin A (MNS blood group)






glycophorin B (MNS blood group)
chr17_+_74381343 1.364 ENST00000392496.3
SPHK1
sphingosine kinase 1
chr2_+_189156586 1.358 ENST00000409830.1
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr11_-_5255696 1.346 ENST00000292901.3
ENST00000417377.1
HBD

hemoglobin, delta

chr10_+_71075552 1.339 ENST00000298649.3
HK1
hexokinase 1
chr3_-_168864427 1.322 ENST00000468789.1
MECOM
MDS1 and EVI1 complex locus
chr4_-_103266219 1.317 ENST00000394833.2
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr2_+_3642545 1.311 ENST00000382062.2
ENST00000236693.7
ENST00000349077.4
COLEC11


collectin sub-family member 11


chr2_+_189156721 1.297 ENST00000409927.1
ENST00000409805.1
GULP1

GULP, engulfment adaptor PTB domain containing 1

chr13_-_46756351 1.289 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr7_+_116654935 1.284 ENST00000432298.1
ENST00000422922.1
ST7

suppression of tumorigenicity 7

chr17_-_72864739 1.282 ENST00000579893.1
ENST00000544854.1
FDXR

ferredoxin reductase

chr4_-_159094194 1.273 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
FAM198B


family with sequence similarity 198, member B


chr8_-_86290333 1.271 ENST00000521846.1
ENST00000523022.1
ENST00000524324.1
ENST00000519991.1
ENST00000520663.1
ENST00000517590.1
ENST00000522579.1
ENST00000522814.1
ENST00000522662.1
ENST00000523858.1
ENST00000519129.1
CA1










carbonic anhydrase I










chr16_+_31539183 1.269 ENST00000302312.4
AHSP
alpha hemoglobin stabilizing protein
chr9_-_124989804 1.267 ENST00000373755.2
ENST00000373754.2
LHX6

LIM homeobox 6

chr12_-_15103621 1.257 ENST00000536592.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr12_+_104359614 1.233 ENST00000266775.9
ENST00000544861.1
TDG

thymine-DNA glycosylase

chr20_-_30795511 1.230 ENST00000246229.4
PLAGL2
pleiomorphic adenoma gene-like 2
chr3_+_148583043 1.216 ENST00000296046.3
CPA3
carboxypeptidase A3 (mast cell)
chr8_-_91095099 1.213 ENST00000265431.3
CALB1
calbindin 1, 28kDa
chr13_-_46716969 1.209 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr15_+_51973550 1.205 ENST00000220478.3
SCG3
secretogranin III
chr16_-_89043377 1.204 ENST00000436887.2
ENST00000448839.1
ENST00000360302.2
CBFA2T3


core-binding factor, runt domain, alpha subunit 2; translocated to, 3


chr7_+_12727250 1.204 ENST00000404894.1
ARL4A
ADP-ribosylation factor-like 4A
chr1_-_155271213 1.196 ENST00000342741.4
PKLR
pyruvate kinase, liver and RBC
chr2_+_189156389 1.161 ENST00000409843.1
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr12_+_104359641 1.160 ENST00000537100.1
TDG
thymine-DNA glycosylase
chr1_-_39339777 1.139 ENST00000397572.2
MYCBP
MYC binding protein
chr19_-_11494975 1.125 ENST00000222139.6
ENST00000592375.2
EPOR

erythropoietin receptor

chr21_-_39870339 1.115 ENST00000429727.2
ENST00000398905.1
ENST00000398907.1
ENST00000453032.2
ENST00000288319.7
ERG




v-ets avian erythroblastosis virus E26 oncogene homolog




chr1_+_43291220 1.111 ENST00000372514.3
ERMAP
erythroblast membrane-associated protein (Scianna blood group)
chr1_-_24469602 1.105 ENST00000270800.1
IL22RA1
interleukin 22 receptor, alpha 1
chrX_+_48380205 1.079 ENST00000446158.1
ENST00000414061.1
EBP

emopamil binding protein (sterol isomerase)

chr2_-_219850277 1.012 ENST00000295727.1
FEV
FEV (ETS oncogene family)
chr15_-_64126084 1.009 ENST00000560316.1
ENST00000443617.2
ENST00000560462.1
ENST00000558532.1
ENST00000561400.1
HERC1




HECT and RLD domain containing E3 ubiquitin protein ligase family member 1




chr8_-_6420777 0.998 ENST00000415216.1
ANGPT2
angiopoietin 2
chr12_+_104359576 0.992 ENST00000392872.3
ENST00000436021.2
TDG

thymine-DNA glycosylase

chr1_-_163172625 0.990 ENST00000527988.1
ENST00000531476.1
ENST00000530507.1
RGS5


regulator of G-protein signaling 5


chr11_-_118213360 0.981 ENST00000529594.1
CD3D
CD3d molecule, delta (CD3-TCR complex)
chr8_-_6420930 0.973 ENST00000325203.5
ANGPT2
angiopoietin 2
chr8_-_6420565 0.967 ENST00000338312.6
ANGPT2
angiopoietin 2
chr1_-_158656488 0.961 ENST00000368147.4
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr7_-_16505440 0.955 ENST00000307068.4
SOSTDC1
sclerostin domain containing 1
chr17_+_37824411 0.952 ENST00000269582.2
PNMT
phenylethanolamine N-methyltransferase
chr8_+_24298597 0.938 ENST00000380789.1
ADAM7
ADAM metallopeptidase domain 7
chr22_+_19710468 0.926 ENST00000366425.3
GP1BB
glycoprotein Ib (platelet), beta polypeptide
chr7_-_23510086 0.923 ENST00000258729.3
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr11_-_32452357 0.919 ENST00000379079.2
ENST00000530998.1
WT1

Wilms tumor 1

chr11_-_66206260 0.913 ENST00000329819.4
ENST00000310999.7
ENST00000430466.2
MRPL11


mitochondrial ribosomal protein L11


chr15_-_79237433 0.896 ENST00000220166.5
CTSH
cathepsin H
chr14_+_102276192 0.893 ENST00000557714.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr8_+_40010989 0.870 ENST00000315792.3
C8orf4
chromosome 8 open reading frame 4
chr2_+_201994569 0.853 ENST00000457277.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr14_+_102276209 0.850 ENST00000445439.3
ENST00000334743.5
ENST00000557095.1
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr12_-_14996355 0.847 ENST00000228936.4
ART4
ADP-ribosyltransferase 4 (Dombrock blood group)
chrX_-_11284095 0.832 ENST00000303025.6
ENST00000534860.1
ARHGAP6

Rho GTPase activating protein 6

chr4_+_74702214 0.826 ENST00000226317.5
ENST00000515050.1
CXCL6

chemokine (C-X-C motif) ligand 6

chr8_+_24298531 0.821 ENST00000175238.6
ADAM7
ADAM metallopeptidase domain 7
chr8_-_72268968 0.820 ENST00000388740.3
EYA1
eyes absent homolog 1 (Drosophila)
chr12_+_29376592 0.819 ENST00000182377.4
FAR2
fatty acyl CoA reductase 2
chr14_+_102276132 0.814 ENST00000350249.3
ENST00000557621.1
ENST00000556946.1
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr1_+_12524965 0.812 ENST00000471923.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr8_-_72268889 0.810 ENST00000388742.4
EYA1
eyes absent homolog 1 (Drosophila)
chr12_+_29376673 0.806 ENST00000547116.1
FAR2
fatty acyl CoA reductase 2
chrX_+_65384182 0.801 ENST00000441993.2
ENST00000419594.1
HEPH

hephaestin

chr8_-_6420759 0.784 ENST00000523120.1
ANGPT2
angiopoietin 2
chr2_-_228028829 0.778 ENST00000396625.3
ENST00000329662.7
COL4A4

collagen, type IV, alpha 4

chr8_-_95449155 0.778 ENST00000481490.2
FSBP
fibrinogen silencer binding protein
chr4_+_154387480 0.770 ENST00000409663.3
ENST00000440693.1
ENST00000409959.3
KIAA0922


KIAA0922


chr2_+_201994208 0.770 ENST00000440180.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr13_+_58206655 0.769 ENST00000377918.3
PCDH17
protocadherin 17
chr2_+_33701286 0.765 ENST00000403687.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr1_-_54872059 0.756 ENST00000371320.3
SSBP3
single stranded DNA binding protein 3
chr15_-_43513187 0.750 ENST00000540029.1
ENST00000441366.2
EPB42

erythrocyte membrane protein band 4.2

chr21_-_34915147 0.746 ENST00000381831.3
ENST00000381839.3
GART

phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase

chrX_+_65384052 0.742 ENST00000336279.5
ENST00000458621.1
HEPH

hephaestin

chr14_-_23877474 0.742 ENST00000405093.3
MYH6
myosin, heavy chain 6, cardiac muscle, alpha
chr7_+_120629653 0.739 ENST00000450913.2
ENST00000340646.5
CPED1

cadherin-like and PC-esterase domain containing 1

chr7_-_20256965 0.734 ENST00000400331.5
ENST00000332878.4
MACC1

metastasis associated in colon cancer 1

chr3_+_157827841 0.732 ENST00000295930.3
ENST00000471994.1
ENST00000464171.1
ENST00000312179.6
ENST00000475278.2
RSRC1




arginine/serine-rich coiled-coil 1




chr8_-_41655107 0.727 ENST00000347528.4
ENST00000289734.7
ENST00000379758.2
ENST00000396945.1
ENST00000396942.1
ENST00000352337.4
ANK1





ankyrin 1, erythrocytic





chr12_+_111843749 0.726 ENST00000341259.2
SH2B3
SH2B adaptor protein 3
chrX_+_84258832 0.713 ENST00000373173.2
APOOL
apolipoprotein O-like
chr6_-_46889694 0.710 ENST00000283296.7
ENST00000362015.4
ENST00000456426.2
GPR116


G protein-coupled receptor 116


chr7_-_1980128 0.703 ENST00000437877.1
MAD1L1
MAD1 mitotic arrest deficient-like 1 (yeast)
chr11_-_62609281 0.701 ENST00000525239.1
ENST00000538098.2
WDR74

WD repeat domain 74

chr12_-_8218997 0.697 ENST00000307637.4
C3AR1
complement component 3a receptor 1
chr3_+_157828152 0.690 ENST00000476899.1
RSRC1
arginine/serine-rich coiled-coil 1
chr7_+_112063192 0.681 ENST00000005558.4
IFRD1
interferon-related developmental regulator 1
chr7_-_95951334 0.675 ENST00000265631.5
SLC25A13
solute carrier family 25 (aspartate/glutamate carrier), member 13
chrX_-_124097620 0.672 ENST00000371130.3
ENST00000422452.2
TENM1

teneurin transmembrane protein 1

chr21_-_33975547 0.665 ENST00000431599.1
C21orf59
chromosome 21 open reading frame 59
chr2_+_201981527 0.652 ENST00000441224.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr3_+_69812877 0.630 ENST00000457080.1
ENST00000328528.6
MITF

microphthalmia-associated transcription factor

chr11_-_64510409 0.623 ENST00000394429.1
ENST00000394428.1
RASGRP2

RAS guanyl releasing protein 2 (calcium and DAG-regulated)

chr12_-_71031185 0.620 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
PTPRB


protein tyrosine phosphatase, receptor type, B


chr5_+_159848807 0.619 ENST00000352433.5
PTTG1
pituitary tumor-transforming 1
chr14_+_29236269 0.610 ENST00000313071.4
FOXG1
forkhead box G1
chr6_+_153019069 0.608 ENST00000532295.1
MYCT1
myc target 1
chr1_+_199996702 0.596 ENST00000367362.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr2_+_201981119 0.594 ENST00000395148.2
CFLAR
CASP8 and FADD-like apoptosis regulator
chr1_+_173793641 0.582 ENST00000361951.4
DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr11_-_89223883 0.574 ENST00000528341.1
NOX4
NADPH oxidase 4
chr8_+_124194752 0.573 ENST00000318462.6
FAM83A
family with sequence similarity 83, member A
chr19_-_4066890 0.558 ENST00000322357.4
ZBTB7A
zinc finger and BTB domain containing 7A
chr20_+_43029911 0.557 ENST00000443598.2
ENST00000316099.4
ENST00000415691.2
HNF4A


hepatocyte nuclear factor 4, alpha


chr6_+_125540951 0.555 ENST00000524679.1
TPD52L1
tumor protein D52-like 1
chr10_+_28822417 0.551 ENST00000428935.1
ENST00000420266.1
WAC

WW domain containing adaptor with coiled-coil

chr2_-_24149977 0.550 ENST00000238789.5
ATAD2B
ATPase family, AAA domain containing 2B
chr11_-_72070206 0.549 ENST00000544382.1
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr4_+_110834033 0.544 ENST00000509793.1
ENST00000265171.5
EGF

epidermal growth factor

chr3_-_119379427 0.542 ENST00000264231.3
ENST00000468801.1
ENST00000538678.1
POPDC2


popeye domain containing 2


chr2_-_188312971 0.539 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
CALCRL


calcitonin receptor-like


chr6_+_37400974 0.534 ENST00000455891.1
ENST00000373451.4
CMTR1

cap methyltransferase 1

chr6_+_89674246 0.528 ENST00000369474.1
AL079342.1
Uncharacterized protein; cDNA FLJ27030 fis, clone SLV07741
chr9_-_75567962 0.528 ENST00000297785.3
ENST00000376939.1
ALDH1A1

aldehyde dehydrogenase 1 family, member A1

chr3_-_58196688 0.517 ENST00000486455.1
DNASE1L3
deoxyribonuclease I-like 3
chr16_+_85646763 0.517 ENST00000411612.1
ENST00000253458.7
GSE1

Gse1 coiled-coil protein

chr1_+_33283043 0.516 ENST00000373476.1
ENST00000373475.5
ENST00000529027.1
ENST00000398243.3
S100PBP



S100P binding protein



chr14_+_103058948 0.506 ENST00000262241.6
RCOR1
REST corepressor 1
chr4_+_74606223 0.499 ENST00000307407.3
ENST00000401931.1
IL8

interleukin 8

chr14_-_21566731 0.498 ENST00000360947.3
ZNF219
zinc finger protein 219
chr1_+_66797687 0.489 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
PDE4B


phosphodiesterase 4B, cAMP-specific


chr6_+_153019023 0.485 ENST00000367245.5
ENST00000529453.1
MYCT1

myc target 1

chr2_+_103035102 0.484 ENST00000264260.2
IL18RAP
interleukin 18 receptor accessory protein
chr5_+_121647764 0.483 ENST00000261368.8
ENST00000379533.2
ENST00000379536.2
ENST00000379538.3
SNCAIP



synuclein, alpha interacting protein



chr6_+_29407083 0.476 ENST00000444197.2
OR10C1
olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
chr3_-_33686743 0.467 ENST00000333778.6
ENST00000539981.1
CLASP2

cytoplasmic linker associated protein 2

chr19_+_35739897 0.466 ENST00000605618.1
ENST00000427250.1
ENST00000601623.1
LSR


lipolysis stimulated lipoprotein receptor


chr12_+_53818855 0.465 ENST00000550839.1
AMHR2
anti-Mullerian hormone receptor, type II
chr1_+_173793777 0.463 ENST00000239457.5
DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr19_+_35739782 0.456 ENST00000347609.4
LSR
lipolysis stimulated lipoprotein receptor
chr11_-_47374246 0.456 ENST00000545968.1
ENST00000399249.2
ENST00000256993.4
MYBPC3


myosin binding protein C, cardiac


chr16_+_85646891 0.446 ENST00000393243.1
GSE1
Gse1 coiled-coil protein
chr2_+_86668464 0.441 ENST00000409064.1
KDM3A
lysine (K)-specific demethylase 3A
chr17_-_60142609 0.440 ENST00000397786.2
MED13
mediator complex subunit 13
chr5_-_150603679 0.440 ENST00000355417.2
CCDC69
coiled-coil domain containing 69
chr11_+_128563948 0.439 ENST00000534087.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr17_-_40288449 0.436 ENST00000552162.1
ENST00000550504.1
RAB5C

RAB5C, member RAS oncogene family

chr1_-_151431647 0.429 ENST00000368863.2
ENST00000409503.1
ENST00000491586.1
ENST00000533351.1
ENST00000540984.1
POGZ




pogo transposable element with ZNF domain




chr11_-_47399942 0.429 ENST00000227163.4
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr14_-_23540747 0.428 ENST00000555566.1
ENST00000338631.6
ENST00000557515.1
ENST00000397341.3
ACIN1



apoptotic chromatin condensation inducer 1



chr4_+_186064395 0.427 ENST00000281456.6
SLC25A4
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr10_+_28822236 0.426 ENST00000347934.4
ENST00000354911.4
WAC

WW domain containing adaptor with coiled-coil

chr12_-_71031220 0.426 ENST00000334414.6
PTPRB
protein tyrosine phosphatase, receptor type, B

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
1.3 6.7 GO:0001955 blood vessel maturation(GO:0001955)
1.2 8.6 GO:0043249 erythrocyte maturation(GO:0043249)
1.1 3.2 GO:0097237 response to cobalt ion(GO:0032025) cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
1.1 3.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.9 3.7 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.7 3.7 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.7 2.2 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.7 2.8 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.6 1.8 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.6 2.4 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.6 1.7 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.5 1.6 GO:0060024 rhythmic synaptic transmission(GO:0060024) positive regulation of sarcomere organization(GO:0060298) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.5 6.3 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.5 1.4 GO:0046521 sphingoid catabolic process(GO:0046521)
0.4 3.4 GO:0045008 depyrimidination(GO:0045008)
0.4 2.1 GO:0015871 choline transport(GO:0015871)
0.3 1.4 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.3 1.3 GO:0001780 neutrophil homeostasis(GO:0001780)
0.3 1.6 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.3 2.9 GO:0020027 hemoglobin metabolic process(GO:0020027)
0.3 0.3 GO:0070601 centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.2 2.0 GO:0016576 histone dephosphorylation(GO:0016576)
0.2 1.2 GO:0050873 brown fat cell differentiation(GO:0050873)
0.2 0.9 GO:0061032 visceral serous pericardium development(GO:0061032)
0.2 0.7 GO:0007518 myoblast fate determination(GO:0007518)
0.2 1.2 GO:0072205 collecting duct development(GO:0072044) metanephric tubule development(GO:0072170) metanephric collecting duct development(GO:0072205) metanephric epithelium development(GO:0072207) metanephric nephron tubule development(GO:0072234) metanephric nephron epithelium development(GO:0072243)
0.2 0.8 GO:0032836 glomerular basement membrane development(GO:0032836)
0.2 0.4 GO:0045726 regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726)
0.2 2.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.2 3.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.2 0.7 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.2 1.3 GO:0021830 interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.2 0.7 GO:0055009 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.2 0.7 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.2 1.0 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.2 2.5 GO:0009713 catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.2 3.5 GO:0006825 copper ion transport(GO:0006825)
0.2 0.6 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.2 1.1 GO:0006855 drug transmembrane transport(GO:0006855)
0.2 2.9 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.1 0.7 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.4 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.1 0.4 GO:0060547 negative regulation of necrotic cell death(GO:0060547)
0.1 0.8 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.1 0.5 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.1 1.2 GO:1902624 positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.1 0.4 GO:0016926 protein desumoylation(GO:0016926)
0.1 0.8 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 0.4 GO:0001907 cytolysis by symbiont of host cells(GO:0001897) killing by symbiont of host cells(GO:0001907) hemolysis by symbiont of host erythrocytes(GO:0019836) disruption by symbiont of host cell(GO:0044004) hemolysis in other organism(GO:0044179) positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010) cytolysis in other organism(GO:0051715) cytolysis in other organism involved in symbiotic interaction(GO:0051801) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1 1.0 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 2.7 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 0.7 GO:0000089 mitotic metaphase(GO:0000089)
0.1 1.1 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.1 2.4 GO:0006911 phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.1 0.3 GO:1903115 regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.1 0.3 GO:0008050 female courtship behavior(GO:0008050)
0.1 0.3 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.1 1.1 GO:0046697 decidualization(GO:0046697)
0.1 0.5 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 0.2 GO:0046101 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.1 0.7 GO:0006069 ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.1 0.6 GO:0035058 positive regulation of neuroblast proliferation(GO:0002052) nonmotile primary cilium assembly(GO:0035058)
0.1 0.3 GO:0048865 stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.1 0.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.3 GO:0030155 regulation of cell adhesion(GO:0030155)
0.1 0.3 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.1 0.9 GO:0031648 protein destabilization(GO:0031648)
0.1 0.8 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.1 0.4 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.4 GO:0032933 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 1.3 GO:0006309 DNA catabolic process, endonucleolytic(GO:0000737) apoptotic DNA fragmentation(GO:0006309)
0.1 0.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 4.4 GO:0030218 erythrocyte differentiation(GO:0030218)
0.1 0.5 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.1 0.3 GO:0001507 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.1 0.3 GO:0030147 obsolete natriuresis(GO:0030147)
0.1 0.4 GO:0007064 mitotic sister chromatid cohesion(GO:0007064) kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383)
0.1 0.2 GO:0072202 cell differentiation involved in metanephros development(GO:0072202)
0.1 0.4 GO:0006477 protein sulfation(GO:0006477)
0.1 0.1 GO:0090345 cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.1 2.5 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.1 0.7 GO:0019228 neuronal action potential(GO:0019228)
0.1 1.0 GO:0030851 granulocyte differentiation(GO:0030851)
0.1 0.4 GO:0015886 heme transport(GO:0015886)
0.1 0.2 GO:0001807 response to protozoan(GO:0001562) type IV hypersensitivity(GO:0001806) regulation of type IV hypersensitivity(GO:0001807)
0.1 3.5 GO:0006826 iron ion transport(GO:0006826)
0.1 0.2 GO:0009103 lipopolysaccharide biosynthetic process(GO:0009103)
0.1 0.3 GO:0009128 AMP catabolic process(GO:0006196) purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1 0.4 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 0.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 2.7 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.1 0.2 GO:2000858 renin-angiotensin regulation of aldosterone production(GO:0002018) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) positive regulation of NAD(P)H oxidase activity(GO:0033864) mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) regulation of mineralocorticoid secretion(GO:2000855) regulation of aldosterone secretion(GO:2000858)
0.0 0.1 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.1 GO:0071344 diphosphate metabolic process(GO:0071344)
0.0 0.0 GO:0019627 urea metabolic process(GO:0019627)
0.0 1.3 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.2 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.5 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.1 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 1.4 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.2 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.6 GO:0050806 positive regulation of synaptic transmission(GO:0050806)
0.0 0.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.2 GO:0060457 negative regulation of digestive system process(GO:0060457)
0.0 0.1 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.2 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 1.0 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 1.6 GO:0001570 vasculogenesis(GO:0001570)
0.0 0.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.4 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 3.1 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.0 0.4 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.5 GO:0034453 microtubule nucleation(GO:0007020) microtubule anchoring(GO:0034453)
0.0 0.6 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.4 GO:0048535 lymph node development(GO:0048535)
0.0 0.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.8 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.6 GO:0051353 positive regulation of oxidoreductase activity(GO:0051353)
0.0 1.0 GO:0051693 actin filament capping(GO:0051693)
0.0 0.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 1.0 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0060259 regulation of feeding behavior(GO:0060259) uterine smooth muscle contraction(GO:0070471) regulation of uterine smooth muscle contraction(GO:0070472) positive regulation of uterine smooth muscle contraction(GO:0070474)
0.0 0.4 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
0.0 0.1 GO:0071372 atrial septum development(GO:0003283) septum primum development(GO:0003284) atrial septum primum morphogenesis(GO:0003289) atrial septum morphogenesis(GO:0060413) cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.1 GO:0010107 potassium ion import(GO:0010107)
0.0 0.6 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0030320 cellular anion homeostasis(GO:0030002) cellular monovalent inorganic anion homeostasis(GO:0030320) cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 1.0 GO:0007162 negative regulation of cell adhesion(GO:0007162)
0.0 0.7 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.1 GO:0009301 snRNA transcription(GO:0009301)
0.0 0.8 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 0.2 GO:0001660 fever generation(GO:0001660)
0.0 0.4 GO:0030032 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0 0.3 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0 0.0 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.0 0.1 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 1.3 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.3 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.7 GO:0050931 melanocyte differentiation(GO:0030318) pigment cell differentiation(GO:0050931)
0.0 0.4 GO:0007032 endosome organization(GO:0007032)
0.0 0.5 GO:0048661 positive regulation of smooth muscle cell proliferation(GO:0048661)
0.0 0.1 GO:0070528 protein kinase C signaling(GO:0070528)
0.0 3.6 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 0.4 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 0.1 GO:0044340 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.0 8.7 GO:0016337 single organismal cell-cell adhesion(GO:0016337)
0.0 0.1 GO:0045822 negative regulation of heart contraction(GO:0045822)
0.0 1.0 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 2.5 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.2 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.4 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.3 GO:0046320 regulation of fatty acid oxidation(GO:0046320)
0.0 0.4 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.3 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.2 GO:0055070 cellular copper ion homeostasis(GO:0006878) COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) copper ion homeostasis(GO:0055070)
0.0 0.1 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.1 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.0 GO:0046621 negative regulation of organ growth(GO:0046621)
0.0 0.2 GO:0006400 tRNA modification(GO:0006400)
0.0 0.2 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.1 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 7.4 GO:0007599 hemostasis(GO:0007599)
0.0 2.4 GO:0006813 potassium ion transport(GO:0006813)
0.0 0.1 GO:0046718 viral entry into host cell(GO:0046718)
0.0 0.6 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 0.0 GO:0060122 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088) inner ear receptor stereocilium organization(GO:0060122)
0.0 0.1 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 1.7 GO:0022900 electron transport chain(GO:0022900)
0.0 1.0 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.1 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.6 GO:0007292 female gamete generation(GO:0007292)
0.0 0.1 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 7.1 GO:0055085 transmembrane transport(GO:0055085)
0.0 0.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0 0.1 GO:0007569 cell aging(GO:0007569)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0042629 mast cell granule(GO:0042629)
1.1 4.2 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.9 13.9 GO:0005833 hemoglobin complex(GO:0005833)
0.5 2.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.5 5.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.4 2.8 GO:0001891 phagocytic cup(GO:0001891)
0.3 2.2 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304)
0.3 4.6 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.3 1.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.2 1.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 3.6 GO:0005861 troponin complex(GO:0005861)
0.1 0.6 GO:0045179 apical cortex(GO:0045179)
0.1 0.8 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.7 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.4 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.3 GO:0043083 synaptic cleft(GO:0043083)
0.1 2.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 6.1 GO:0016605 PML body(GO:0016605)
0.1 1.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 3.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 1.2 GO:0042627 chylomicron(GO:0042627)
0.1 0.9 GO:0032982 myosin filament(GO:0032982)
0.0 0.5 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.3 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 7.2 GO:0016607 nuclear speck(GO:0016607)
0.0 0.2 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.3 GO:0042827 platelet dense granule(GO:0042827)
0.0 0.1 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.2 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.5 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.0 3.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.3 GO:0016272 prefoldin complex(GO:0016272)
0.0 1.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 2.8 GO:0005643 nuclear pore(GO:0005643)
0.0 0.2 GO:0030018 Z disc(GO:0030018)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.5 GO:0030175 filopodium(GO:0030175)
0.0 0.9 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 0.3 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)
0.0 3.1 GO:0000793 condensed chromosome(GO:0000793)
0.0 1.2 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.2 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.2 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 3.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.8 GO:0016459 myosin complex(GO:0016459)
0.0 0.6 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 1.0 GO:0045202 synapse(GO:0045202)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.8 GO:0070469 respiratory chain(GO:0070469)
0.0 0.6 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0050613 delta14-sterol reductase activity(GO:0050613)
1.1 3.4 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
1.1 14.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.8 2.5 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
0.8 3.2 GO:0004998 transferrin receptor activity(GO:0004998)
0.6 3.7 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.5 0.5 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.5 1.6 GO:0050062 long-chain-fatty-acyl-CoA reductase activity(GO:0050062)
0.5 11.7 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.5 1.5 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.5 3.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.5 2.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.5 2.8 GO:0030955 potassium ion binding(GO:0030955)
0.4 1.3 GO:0016731 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.4 5.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.4 1.6 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.4 2.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.3 4.0 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.3 2.6 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.3 1.6 GO:0031708 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.3 0.9 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.2 0.7 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.2 1.4 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.2 1.3 GO:0030492 hemoglobin binding(GO:0030492)
0.2 3.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.2 0.2 GO:0031420 alkali metal ion binding(GO:0031420)
0.2 1.2 GO:0005499 vitamin D binding(GO:0005499)
0.2 5.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 6.3 GO:0050699 WW domain binding(GO:0050699)
0.2 1.3 GO:0004340 glucokinase activity(GO:0004340)
0.2 0.5 GO:0004948 calcitonin receptor activity(GO:0004948)
0.2 1.0 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.2 0.8 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.2 0.7 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.2 0.6 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.2 3.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 0.6 GO:0016882 cyclo-ligase activity(GO:0016882)
0.1 16.1 GO:0005178 integrin binding(GO:0005178)
0.1 0.4 GO:0015217 purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) ATP:ADP antiporter activity(GO:0005471) ADP transmembrane transporter activity(GO:0015217)
0.1 0.4 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 0.9 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 1.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 1.8 GO:0017127 cholesterol transporter activity(GO:0017127)
0.1 0.5 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 0.7 GO:0004875 complement receptor activity(GO:0004875)
0.1 1.1 GO:0004904 interferon receptor activity(GO:0004904)
0.1 1.1 GO:0060229 lipase activator activity(GO:0060229)
0.1 0.8 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.6 GO:0031432 titin binding(GO:0031432)
0.1 1.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 1.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 1.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.4 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.1 0.2 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.1 0.3 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 0.2 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 3.0 GO:1990782 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.1 0.3 GO:0004882 androgen receptor activity(GO:0004882)
0.1 0.5 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.1 2.8 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.1 0.6 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 3.9 GO:0005507 copper ion binding(GO:0005507)
0.1 0.5 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.1 0.3 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 5.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 0.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 4.1 GO:0051015 actin filament binding(GO:0051015)
0.1 0.5 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.2 GO:0009384 N-acylmannosamine kinase activity(GO:0009384)
0.1 0.3 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 0.8 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.3 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.8 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.7 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 1.9 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.4 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.9 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.5 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.7 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.3 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0004796 thromboxane-A synthase activity(GO:0004796)
0.0 0.3 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.3 GO:0030284 estrogen receptor activity(GO:0030284) estrogen response element binding(GO:0034056)
0.0 0.3 GO:0070513 death domain binding(GO:0070513)
0.0 1.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.7 GO:0001228 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.3 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 2.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.0 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.3 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 1.2 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.6 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 1.0 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 1.9 GO:0010843 obsolete promoter binding(GO:0010843)
0.0 0.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.4 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.4 GO:0002039 p53 binding(GO:0002039)
0.0 1.8 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.2 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 7.2 GO:0016563 obsolete transcription activator activity(GO:0016563)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.8 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.6 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.7 GO:0008234 cysteine-type peptidase activity(GO:0008234)
0.0 0.1 GO:0060590 ATPase regulator activity(GO:0060590)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.8 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.2 GO:0005003 ephrin receptor activity(GO:0005003)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.6 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 3.8 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.0 0.7 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.5 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 1.1 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 1.5 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway