Motif ID: GAUUGUC
Z-value: 0.982
Mature miRNA associated with seed GAUUGUC:
| Name | miRBase Accession |
|---|---|
| hsa-miR-219a-5p | MIMAT0000276 |
| hsa-miR-4782-3p | MIMAT0019945 |
| hsa-miR-6766-3p | MIMAT0027433 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.0 | GO:0061298 | progesterone secretion(GO:0042701) retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299) |
| 0.2 | 0.4 | GO:0007182 | common-partner SMAD protein phosphorylation(GO:0007182) |
| 0.1 | 0.8 | GO:0060528 | secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528) |
| 0.1 | 0.8 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) |
| 0.1 | 0.6 | GO:0006930 | substrate-dependent cell migration, cell extension(GO:0006930) |
| 0.1 | 0.6 | GO:0090009 | primitive streak formation(GO:0090009) |
| 0.1 | 0.4 | GO:0031077 | post-embryonic camera-type eye development(GO:0031077) Spemann organizer formation(GO:0060061) |
| 0.1 | 0.6 | GO:0032696 | negative regulation of interleukin-13 production(GO:0032696) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121) |
| 0.1 | 1.0 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
| 0.1 | 0.5 | GO:0045722 | response to muscle activity(GO:0014850) positive regulation of gluconeogenesis(GO:0045722) |
| 0.1 | 0.2 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
| 0.1 | 0.5 | GO:0061099 | negative regulation of protein tyrosine kinase activity(GO:0061099) |
| 0.1 | 0.4 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 0.1 | 1.2 | GO:0071044 | histone mRNA catabolic process(GO:0071044) |
| 0.1 | 0.3 | GO:0006848 | pyruvate transport(GO:0006848) |
| 0.1 | 2.0 | GO:0030851 | granulocyte differentiation(GO:0030851) |
| 0.1 | 0.3 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.1 | 0.2 | GO:0008050 | female courtship behavior(GO:0008050) |
| 0.1 | 0.7 | GO:0060324 | face development(GO:0060324) |
| 0.1 | 0.3 | GO:0000729 | DNA double-strand break processing(GO:0000729) |
| 0.0 | 0.3 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
| 0.0 | 0.6 | GO:0035024 | negative regulation of Rho protein signal transduction(GO:0035024) |
| 0.0 | 0.1 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.0 | 0.2 | GO:0021615 | glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615) |
| 0.0 | 0.6 | GO:0045749 | obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749) |
| 0.0 | 0.1 | GO:2000644 | low-density lipoprotein particle receptor catabolic process(GO:0032802) regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of neurotrophin production(GO:0032899) negative regulation of neurotrophin production(GO:0032900) negative regulation of transforming growth factor beta production(GO:0071635) regulation of receptor catabolic process(GO:2000644) |
| 0.0 | 0.2 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 0.0 | 0.3 | GO:0051973 | positive regulation of telomerase activity(GO:0051973) |
| 0.0 | 0.2 | GO:0071699 | olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699) |
| 0.0 | 0.6 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
| 0.0 | 0.3 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.0 | 0.1 | GO:0042518 | negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518) |
| 0.0 | 0.5 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
| 0.0 | 0.1 | GO:0032933 | SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501) |
| 0.0 | 0.1 | GO:0007389 | pattern specification process(GO:0007389) |
| 0.0 | 0.1 | GO:0071883 | adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) |
| 0.0 | 0.6 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
| 0.0 | 0.1 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) vagina development(GO:0060068) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) |
| 0.0 | 0.2 | GO:0051016 | barbed-end actin filament capping(GO:0051016) |
| 0.0 | 0.2 | GO:0034453 | microtubule anchoring(GO:0034453) |
| 0.0 | 0.1 | GO:0033137 | negative regulation of peptidyl-serine phosphorylation(GO:0033137) |
| 0.0 | 0.1 | GO:0048840 | otolith development(GO:0048840) |
| 0.0 | 1.1 | GO:0034339 | obsolete regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor(GO:0034339) |
| 0.0 | 0.1 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.3 | GO:0031372 | UBC13-MMS2 complex(GO:0031372) |
| 0.1 | 1.2 | GO:0016442 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
| 0.1 | 0.3 | GO:0001940 | male pronucleus(GO:0001940) |
| 0.1 | 0.4 | GO:0071817 | MMXD complex(GO:0071817) |
| 0.1 | 0.2 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
| 0.1 | 0.3 | GO:0042405 | nuclear RNA export factor complex(GO:0042272) nuclear inclusion body(GO:0042405) |
| 0.0 | 0.6 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.0 | 0.2 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) histone pre-mRNA 3'end processing complex(GO:0071204) |
| 0.0 | 0.4 | GO:0008091 | spectrin(GO:0008091) |
| 0.0 | 0.1 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
| 0.0 | 0.5 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.0 | 0.2 | GO:0019908 | nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908) |
| 0.0 | 0.4 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
| 0.0 | 0.2 | GO:0000808 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 0.0 | 0.3 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 0.2 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.0 | 0.7 | GO:0005798 | Golgi-associated vesicle(GO:0005798) |
| 0.0 | 0.1 | GO:0048786 | presynaptic active zone(GO:0048786) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.8 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
| 0.1 | 0.6 | GO:0035326 | enhancer binding(GO:0035326) |
| 0.1 | 0.5 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
| 0.1 | 0.6 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
| 0.1 | 0.2 | GO:0005017 | platelet-derived growth factor-activated receptor activity(GO:0005017) |
| 0.1 | 1.2 | GO:0016896 | exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896) |
| 0.1 | 0.3 | GO:0050833 | pyruvate secondary active transmembrane transporter activity(GO:0005477) pyruvate transmembrane transporter activity(GO:0050833) |
| 0.1 | 1.4 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.1 | 0.4 | GO:0030955 | potassium ion binding(GO:0030955) |
| 0.1 | 0.2 | GO:0043515 | kinetochore binding(GO:0043515) |
| 0.1 | 0.2 | GO:0004768 | stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) |
| 0.1 | 0.2 | GO:0016524 | latrotoxin receptor activity(GO:0016524) |
| 0.0 | 0.6 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617) |
| 0.0 | 0.1 | GO:0010861 | thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375) |
| 0.0 | 0.1 | GO:0042285 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
| 0.0 | 0.1 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
| 0.0 | 0.5 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.0 | 0.2 | GO:0003997 | acyl-CoA oxidase activity(GO:0003997) |
| 0.0 | 0.1 | GO:0034594 | phosphatidylinositol trisphosphate phosphatase activity(GO:0034594) |
| 0.0 | 0.3 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 0.0 | 0.1 | GO:0005315 | inorganic phosphate transmembrane transporter activity(GO:0005315) |
| 0.0 | 0.6 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.0 | 0.2 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.0 | 0.4 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.0 | 0.1 | GO:0004938 | alpha2-adrenergic receptor activity(GO:0004938) |
| 0.0 | 0.1 | GO:0034056 | estrogen response element binding(GO:0034056) |
| 0.0 | 0.1 | GO:0048406 | nerve growth factor binding(GO:0048406) |
| 0.0 | 0.6 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
| 0.0 | 0.4 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
| 0.0 | 1.3 | GO:0003707 | steroid hormone receptor activity(GO:0003707) |
| 0.0 | 0.3 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.0 | 0.2 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.0 | 0.1 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.0 | 0.6 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.0 | 0.2 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.0 | 0.1 | GO:0001727 | lipid kinase activity(GO:0001727) |
| 0.0 | 0.1 | GO:0016018 | cyclosporin A binding(GO:0016018) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
