Motif ID: GCUACAU

Z-value: 0.814


Mature miRNA associated with seed GCUACAU:

NamemiRBase Accession
hsa-miR-221-3p MIMAT0000278
hsa-miR-222-3p MIMAT0000279



Activity profile for motif GCUACAU.

activity profile for motif GCUACAU


Sorted Z-values histogram for motif GCUACAU

Sorted Z-values for motif GCUACAU



Network of associatons between targets according to the STRING database.



First level regulatory network of GCUACAU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_61591337 0.916 ENST00000423902.2
CHD7
chromodomain helicase DNA binding protein 7
chr12_+_12870055 0.681 ENST00000228872.4
CDKN1B
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
chr5_-_175964366 0.550 ENST00000274811.4
RNF44
ring finger protein 44
chr14_+_74111578 0.546 ENST00000554113.1
ENST00000555631.2
ENST00000553645.2
ENST00000311089.3
ENST00000555919.3
ENST00000554339.1
ENST00000554871.1
DNAL1






dynein, axonemal, light chain 1






chr2_-_24149977 0.506 ENST00000238789.5
ATAD2B
ATPase family, AAA domain containing 2B
chr6_+_16129308 0.400 ENST00000356840.3
ENST00000349606.4
MYLIP

myosin regulatory light chain interacting protein

chr16_+_22308717 0.388 ENST00000299853.5
ENST00000564209.1
ENST00000565358.1
ENST00000418581.2
ENST00000564883.1
ENST00000359210.4
ENST00000563024.1
POLR3E






polymerase (RNA) III (DNA directed) polypeptide E (80kD)






chr14_-_36278412 0.377 ENST00000389698.3
ENST00000258840.6
RALGAPA1

Ral GTPase activating protein, alpha subunit 1 (catalytic)

chr2_+_64681219 0.371 ENST00000238875.5
LGALSL
lectin, galactoside-binding-like
chr2_-_43453734 0.363 ENST00000282388.3
ZFP36L2
ZFP36 ring finger protein-like 2
chr21_+_40177143 0.356 ENST00000360214.3
ETS2
v-ets avian erythroblastosis virus E26 oncogene homolog 2
chr12_-_121342170 0.355 ENST00000353487.2
SPPL3
signal peptide peptidase like 3
chr1_-_117210290 0.329 ENST00000369483.1
ENST00000369486.3
IGSF3

immunoglobulin superfamily, member 3

chr2_+_178257372 0.286 ENST00000264167.4
ENST00000409888.1
AGPS

alkylglycerone phosphate synthase

chr6_-_16761678 0.281 ENST00000244769.4
ENST00000436367.1
ATXN1

ataxin 1

chr12_-_102874416 0.271 ENST00000392904.1
ENST00000337514.6
IGF1

insulin-like growth factor 1 (somatomedin C)

chr5_+_140254884 0.262 ENST00000398631.2
PCDHA12
protocadherin alpha 12
chr6_-_10415470 0.259 ENST00000379604.2
ENST00000379613.3
TFAP2A

transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)

chr4_-_185395672 0.248 ENST00000393593.3
IRF2
interferon regulatory factor 2
chr9_-_115095883 0.247 ENST00000450374.1
ENST00000374255.2
ENST00000334318.6
ENST00000374257.1
PTBP3



polypyrimidine tract binding protein 3



chr16_+_69599861 0.245 ENST00000354436.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr18_+_43753974 0.239 ENST00000282059.6
ENST00000321319.6
C18orf25

chromosome 18 open reading frame 25

chr2_-_152955537 0.238 ENST00000201943.5
ENST00000539935.1
CACNB4

calcium channel, voltage-dependent, beta 4 subunit

chrX_+_146993449 0.236 ENST00000218200.8
ENST00000370471.3
ENST00000370477.1
FMR1


fragile X mental retardation 1


chr4_+_144257915 0.231 ENST00000262995.4
GAB1
GRB2-associated binding protein 1
chr10_-_94003003 0.226 ENST00000412050.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr1_+_28696111 0.224 ENST00000373839.3
PHACTR4
phosphatase and actin regulator 4
chr3_-_182698381 0.223 ENST00000292782.4
DCUN1D1
DCN1, defective in cullin neddylation 1, domain containing 1
chr7_+_138916231 0.217 ENST00000473989.3
ENST00000288561.8
UBN2

ubinuclein 2

chrX_+_23352133 0.216 ENST00000379361.4
PTCHD1
patched domain containing 1
chr5_+_140213815 0.212 ENST00000525929.1
ENST00000378125.3
PCDHA7

protocadherin alpha 7

chr6_+_47445467 0.200 ENST00000359314.5
CD2AP
CD2-associated protein
chr2_-_68479614 0.196 ENST00000234310.3
PPP3R1
protein phosphatase 3, regulatory subunit B, alpha
chr1_+_114472222 0.195 ENST00000369558.1
ENST00000369561.4
HIPK1

homeodomain interacting protein kinase 1

chr16_-_73082274 0.189 ENST00000268489.5
ZFHX3
zinc finger homeobox 3
chr1_+_220701456 0.185 ENST00000366918.4
ENST00000402574.1
MARK1

MAP/microtubule affinity-regulating kinase 1

chr6_-_116381918 0.185 ENST00000606080.1
FRK
fyn-related kinase
chr5_+_140345820 0.185 ENST00000289269.5
PCDHAC2
protocadherin alpha subfamily C, 2
chr5_+_140235469 0.183 ENST00000506939.2
ENST00000307360.5
PCDHA10

protocadherin alpha 10

chr15_-_56535464 0.178 ENST00000559447.2
ENST00000422057.1
ENST00000317318.6
ENST00000423270.1
RFX7



regulatory factor X, 7



chr12_+_70636765 0.177 ENST00000552231.1
ENST00000229195.3
ENST00000547780.1
ENST00000418359.3
CNOT2



CCR4-NOT transcription complex, subunit 2



chr4_+_144434584 0.177 ENST00000283131.3
SMARCA5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr3_-_129407535 0.175 ENST00000432054.2
TMCC1
transmembrane and coiled-coil domain family 1
chr22_+_21271714 0.173 ENST00000354336.3
CRKL
v-crk avian sarcoma virus CT10 oncogene homolog-like
chr4_-_55991752 0.173 ENST00000263923.4
KDR
kinase insert domain receptor (a type III receptor tyrosine kinase)
chr17_+_61627814 0.169 ENST00000310827.4
ENST00000431926.1
ENST00000415273.2
DCAF7


DDB1 and CUL4 associated factor 7


chr5_+_140261703 0.169 ENST00000409494.1
ENST00000289272.2
PCDHA13

protocadherin alpha 13

chr2_-_160472952 0.168 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
BAZ2B



bromodomain adjacent to zinc finger domain, 2B



chr10_+_74033672 0.166 ENST00000307365.3
DDIT4
DNA-damage-inducible transcript 4
chr7_+_20370746 0.165 ENST00000222573.4
ITGB8
integrin, beta 8
chr21_-_40685477 0.163 ENST00000342449.3
BRWD1
bromodomain and WD repeat domain containing 1
chr17_-_76356148 0.162 ENST00000587578.1
ENST00000330871.2
SOCS3

suppressor of cytokine signaling 3

chr5_+_140248518 0.161 ENST00000398640.2
PCDHA11
protocadherin alpha 11
chr8_+_106330920 0.159 ENST00000407775.2
ZFPM2
zinc finger protein, FOG family member 2
chr6_+_7107999 0.155 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
RREB1


ras responsive element binding protein 1


chrX_-_110655391 0.154 ENST00000356915.2
ENST00000356220.3
DCX

doublecortin

chr5_+_140306478 0.148 ENST00000253807.2
PCDHAC1
protocadherin alpha subfamily C, 1
chr2_+_109335929 0.145 ENST00000283195.6
RANBP2
RAN binding protein 2
chr15_+_44829255 0.144 ENST00000261868.5
ENST00000424492.3
EIF3J

eukaryotic translation initiation factor 3, subunit J

chr5_+_140220769 0.141 ENST00000531613.1
ENST00000378123.3
PCDHA8

protocadherin alpha 8

chr2_-_100106419 0.136 ENST00000393445.3
ENST00000258428.3
REV1

REV1, polymerase (DNA directed)

chr12_+_67663056 0.130 ENST00000545606.1
CAND1
cullin-associated and neddylation-dissociated 1
chr12_+_20522179 0.127 ENST00000359062.3
PDE3A
phosphodiesterase 3A, cGMP-inhibited
chr10_-_11653753 0.127 ENST00000609104.1
USP6NL
USP6 N-terminal like
chr1_-_41131326 0.124 ENST00000372684.3
RIMS3
regulating synaptic membrane exocytosis 3
chr8_+_11561660 0.122 ENST00000526716.1
ENST00000335135.4
ENST00000528027.1
GATA4


GATA binding protein 4


chr11_+_119076745 0.120 ENST00000264033.4
CBL
Cbl proto-oncogene, E3 ubiquitin protein ligase
chr5_+_161274685 0.118 ENST00000428797.2
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr10_-_118764862 0.114 ENST00000260777.10
KIAA1598
KIAA1598
chr3_+_183353356 0.109 ENST00000242810.6
ENST00000493074.1
ENST00000437402.1
ENST00000454495.2
ENST00000473045.1
ENST00000468101.1
ENST00000427201.2
ENST00000482138.1
ENST00000454652.2
KLHL24








kelch-like family member 24








chr1_-_150849208 0.109 ENST00000358595.5
ARNT
aryl hydrocarbon receptor nuclear translocator
chr6_+_152011628 0.108 ENST00000404742.1
ENST00000440973.1
ESR1

estrogen receptor 1

chr1_-_10856694 0.105 ENST00000377022.3
ENST00000344008.5
CASZ1

castor zinc finger 1

chr1_+_24286287 0.103 ENST00000334351.7
ENST00000374468.1
PNRC2

proline-rich nuclear receptor coactivator 2

chr19_-_1652575 0.103 ENST00000587235.1
ENST00000262965.5
TCF3

transcription factor 3

chr10_+_120789223 0.102 ENST00000425699.1
NANOS1
nanos homolog 1 (Drosophila)
chr13_+_26828275 0.100 ENST00000381527.3
CDK8
cyclin-dependent kinase 8
chr9_+_103790991 0.099 ENST00000374874.3
LPPR1
Lipid phosphate phosphatase-related protein type 1
chr5_+_79703823 0.099 ENST00000338008.5
ENST00000510158.1
ENST00000505560.1
ZFYVE16


zinc finger, FYVE domain containing 16


chr16_-_30798492 0.098 ENST00000262525.4
ZNF629
zinc finger protein 629
chr5_+_140201183 0.098 ENST00000529619.1
ENST00000529859.1
ENST00000378126.3
PCDHA5


protocadherin alpha 5


chr1_-_205601064 0.094 ENST00000357992.4
ENST00000289703.4
ELK4

ELK4, ETS-domain protein (SRF accessory protein 1)

chr15_-_41624685 0.094 ENST00000560640.1
ENST00000220514.3
OIP5

Opa interacting protein 5

chr6_-_86352642 0.092 ENST00000355238.6
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr4_-_176923483 0.091 ENST00000280187.7
ENST00000512509.1
GPM6A

glycoprotein M6A

chr12_+_69864129 0.089 ENST00000547219.1
ENST00000299293.2
ENST00000549921.1
ENST00000550316.1
ENST00000548154.1
ENST00000547414.1
ENST00000550389.1
ENST00000550937.1
ENST00000549092.1
ENST00000550169.1
FRS2









fibroblast growth factor receptor substrate 2









chr2_-_2334888 0.086 ENST00000428368.2
ENST00000399161.2
MYT1L

myelin transcription factor 1-like

chr14_-_99737565 0.086 ENST00000357195.3
BCL11B
B-cell CLL/lymphoma 11B (zinc finger protein)
chr12_+_56473628 0.085 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
ERBB3


v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3


chr1_+_63833261 0.084 ENST00000371108.4
ALG6
ALG6, alpha-1,3-glucosyltransferase
chr9_-_3525968 0.083 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
RFX3


regulatory factor X, 3 (influences HLA class II expression)


chr1_-_89357179 0.081 ENST00000448623.1
ENST00000418217.1
ENST00000370500.5
GTF2B


general transcription factor IIB


chr12_+_94542459 0.080 ENST00000258526.4
PLXNC1
plexin C1
chr5_+_140207536 0.078 ENST00000529310.1
ENST00000527624.1
PCDHA6

protocadherin alpha 6

chr10_-_99094458 0.075 ENST00000371019.2
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr1_+_150980889 0.073 ENST00000450884.1
ENST00000271620.3
ENST00000271619.8
ENST00000368937.1
ENST00000431193.1
ENST00000368936.1
PRUNE





prune exopolyphosphatase





chr16_+_68119440 0.073 ENST00000346183.3
ENST00000329524.4
NFATC3

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3

chrX_+_28605516 0.069 ENST00000378993.1
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr1_-_207224307 0.066 ENST00000315927.4
YOD1
YOD1 deubiquitinase
chr5_+_67511524 0.064 ENST00000521381.1
ENST00000521657.1
PIK3R1

phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

chr2_-_208030647 0.063 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr3_+_47324424 0.062 ENST00000437353.1
ENST00000232766.5
ENST00000455924.2
KLHL18


kelch-like family member 18


chr14_+_77228532 0.062 ENST00000167106.4
ENST00000554237.1
VASH1

vasohibin 1

chr17_+_36861735 0.060 ENST00000378137.5
ENST00000325718.7
MLLT6

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6

chr16_+_67596310 0.059 ENST00000264010.4
ENST00000401394.1
CTCF

CCCTC-binding factor (zinc finger protein)

chr20_+_56964169 0.059 ENST00000475243.1
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr1_+_222791417 0.058 ENST00000344922.5
ENST00000344441.6
ENST00000344507.1
MIA3


melanoma inhibitory activity family, member 3


chr2_+_48541776 0.058 ENST00000413569.1
ENST00000340553.3
FOXN2

forkhead box N2

chr16_-_11350036 0.057 ENST00000332029.2
SOCS1
suppressor of cytokine signaling 1
chr12_-_123011536 0.056 ENST00000331738.7
ENST00000354654.2
RSRC2

arginine/serine-rich coiled-coil 2

chr8_+_28747884 0.056 ENST00000287701.10
ENST00000444075.1
ENST00000403668.2
ENST00000519662.1
ENST00000558662.1
ENST00000523613.1
ENST00000560599.1
ENST00000397358.3
HMBOX1







homeobox containing 1







chr5_-_168006591 0.055 ENST00000239231.6
PANK3
pantothenate kinase 3
chr18_-_51751132 0.054 ENST00000256429.3
MBD2
methyl-CpG binding domain protein 2
chr3_+_171758344 0.053 ENST00000336824.4
ENST00000423424.1
FNDC3B

fibronectin type III domain containing 3B

chr15_-_101792137 0.050 ENST00000254190.3
CHSY1
chondroitin sulfate synthase 1
chr5_+_140186647 0.048 ENST00000512229.2
ENST00000356878.4
ENST00000530339.1
PCDHA4


protocadherin alpha 4


chr7_+_107110488 0.044 ENST00000304402.4
GPR22
G protein-coupled receptor 22
chr1_+_27022485 0.042 ENST00000324856.7
ARID1A
AT rich interactive domain 1A (SWI-like)
chr3_-_24536253 0.039 ENST00000428492.1
ENST00000396671.2
ENST00000431815.1
ENST00000418247.1
ENST00000416420.1
ENST00000356447.4
THRB





thyroid hormone receptor, beta





chr14_+_72399833 0.039 ENST00000553530.1
ENST00000556437.1
RGS6

regulator of G-protein signaling 6

chr14_-_21905395 0.038 ENST00000430710.3
ENST00000553283.1
CHD8

chromodomain helicase DNA binding protein 8

chr2_+_60983361 0.037 ENST00000238714.3
PAPOLG
poly(A) polymerase gamma
chr13_-_103053946 0.037 ENST00000376131.4
FGF14
fibroblast growth factor 14
chr5_+_140165876 0.034 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
PCDHA1


protocadherin alpha 1


chr3_-_11762202 0.034 ENST00000445411.1
ENST00000404339.1
ENST00000273038.3
VGLL4


vestigial like 4 (Drosophila)


chr11_+_9406169 0.033 ENST00000379719.3
ENST00000527431.1
IPO7

importin 7

chr13_+_53226963 0.032 ENST00000343788.6
ENST00000535397.1
ENST00000310528.8
SUGT1


SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)


chr10_+_22610124 0.032 ENST00000376663.3
BMI1
BMI1 polycomb ring finger oncogene
chr12_+_41831485 0.031 ENST00000539469.2
ENST00000298919.7
PDZRN4

PDZ domain containing ring finger 4

chr10_+_114709999 0.031 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
TCF7L2






transcription factor 7-like 2 (T-cell specific, HMG-box)






chr11_+_31531291 0.031 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
ELP4


elongator acetyltransferase complex subunit 4


chr8_-_65711310 0.029 ENST00000310193.3
CYP7B1
cytochrome P450, family 7, subfamily B, polypeptide 1
chr13_+_88324870 0.029 ENST00000325089.6
SLITRK5
SLIT and NTRK-like family, member 5
chr9_-_114246635 0.027 ENST00000338205.5
KIAA0368
KIAA0368
chr11_-_70507901 0.027 ENST00000449833.2
ENST00000357171.3
ENST00000449116.2
SHANK2


SH3 and multiple ankyrin repeat domains 2


chr5_+_140180635 0.025 ENST00000522353.2
ENST00000532566.2
PCDHA3

protocadherin alpha 3

chr6_+_37225540 0.025 ENST00000373491.3
TBC1D22B
TBC1 domain family, member 22B
chr22_-_39151463 0.024 ENST00000405510.1
ENST00000433561.1
SUN2

Sad1 and UNC84 domain containing 2

chr2_+_113033164 0.024 ENST00000409871.1
ENST00000343936.4
ZC3H6

zinc finger CCCH-type containing 6

chr17_-_37607497 0.024 ENST00000394287.3
ENST00000300651.6
MED1

mediator complex subunit 1

chr8_+_26149007 0.022 ENST00000380737.3
ENST00000524169.1
PPP2R2A

protein phosphatase 2, regulatory subunit B, alpha

chr7_-_25019760 0.022 ENST00000352860.1
ENST00000353930.1
ENST00000431825.2
ENST00000313367.2
OSBPL3



oxysterol binding protein-like 3



chr5_+_140174429 0.022 ENST00000520672.2
ENST00000378132.1
ENST00000526136.1
PCDHA2


protocadherin alpha 2


chr5_-_150948414 0.021 ENST00000261800.5
FAT2
FAT atypical cadherin 2
chr1_+_33283043 0.019 ENST00000373476.1
ENST00000373475.5
ENST00000529027.1
ENST00000398243.3
S100PBP



S100P binding protein



chr20_-_48532019 0.019 ENST00000289431.5
SPATA2
spermatogenesis associated 2
chr4_-_87281224 0.019 ENST00000395169.3
ENST00000395161.2
MAPK10

mitogen-activated protein kinase 10

chr16_-_31021921 0.017 ENST00000215095.5
STX1B
syntaxin 1B
chr6_+_44355257 0.017 ENST00000371477.3
CDC5L
cell division cycle 5-like
chr2_+_111878483 0.017 ENST00000308659.8
ENST00000357757.2
ENST00000393253.2
ENST00000337565.5
ENST00000393256.3
BCL2L11




BCL2-like 11 (apoptosis facilitator)




chr11_+_118754475 0.017 ENST00000292174.4
CXCR5
chemokine (C-X-C motif) receptor 5
chr6_+_45389893 0.016 ENST00000371432.3
RUNX2
runt-related transcription factor 2
chr2_+_228336849 0.016 ENST00000409979.2
ENST00000310078.8
AGFG1

ArfGAP with FG repeats 1

chr2_-_69870835 0.015 ENST00000409085.4
ENST00000406297.3
AAK1

AP2 associated kinase 1

chr22_-_38380543 0.014 ENST00000396884.2
SOX10
SRY (sex determining region Y)-box 10
chr12_+_113229737 0.014 ENST00000551052.1
ENST00000415485.3
RPH3A

rabphilin 3A homolog (mouse)

chr8_-_133493200 0.013 ENST00000388996.4
KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr22_+_21213259 0.013 ENST00000215730.7
SNAP29
synaptosomal-associated protein, 29kDa
chr17_+_36508111 0.013 ENST00000331159.5
ENST00000577233.1
SOCS7

suppressor of cytokine signaling 7

chr12_+_56401268 0.012 ENST00000262032.5
IKZF4
IKAROS family zinc finger 4 (Eos)
chr8_+_23386305 0.012 ENST00000519973.1
SLC25A37
solute carrier family 25 (mitochondrial iron transporter), member 37
chr17_+_41177220 0.012 ENST00000587250.2
ENST00000544533.1
RND2

Rho family GTPase 2

chr7_-_105029329 0.011 ENST00000393651.3
ENST00000460391.1
SRPK2

SRSF protein kinase 2

chr3_+_169684553 0.010 ENST00000337002.4
ENST00000480708.1
SEC62

SEC62 homolog (S. cerevisiae)

chrX_-_72434628 0.010 ENST00000536638.1
ENST00000373517.3
NAP1L2

nucleosome assembly protein 1-like 2

chr6_+_163835669 0.010 ENST00000453779.2
ENST00000275262.7
ENST00000392127.2
ENST00000361752.3
QKI



QKI, KH domain containing, RNA binding



chr14_-_64010046 0.010 ENST00000337537.3
PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr14_-_91720224 0.009 ENST00000238699.3
ENST00000531499.2
GPR68

G protein-coupled receptor 68

chr2_+_178077477 0.008 ENST00000411529.2
ENST00000435711.1
HNRNPA3

heterogeneous nuclear ribonucleoprotein A3

chr9_+_96214166 0.008 ENST00000375389.3
ENST00000333936.5
ENST00000340893.4
FAM120A


family with sequence similarity 120A


chr9_+_96338860 0.008 ENST00000375376.4
PHF2
PHD finger protein 2
chr3_+_16926441 0.008 ENST00000418129.2
ENST00000396755.2
PLCL2

phospholipase C-like 2

chr12_+_111471828 0.006 ENST00000261726.6
CUX2
cut-like homeobox 2
chr1_+_110091189 0.006 ENST00000369851.4
GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr1_-_220445757 0.005 ENST00000358951.2
RAB3GAP2
RAB3 GTPase activating protein subunit 2 (non-catalytic)
chr5_+_140227048 0.004 ENST00000532602.1
PCDHA9
protocadherin alpha 9
chr7_+_77325738 0.003 ENST00000334955.8
RSBN1L
round spermatid basic protein 1-like
chr2_+_208394616 0.003 ENST00000432329.2
ENST00000353267.3
ENST00000445803.1
CREB1


cAMP responsive element binding protein 1


chr16_+_67063036 0.003 ENST00000290858.6
ENST00000564034.1
CBFB

core-binding factor, beta subunit

chr3_-_170626418 0.001 ENST00000474096.1
ENST00000295822.2
EIF5A2

eukaryotic translation initiation factor 5A2

chr17_+_42836329 0.001 ENST00000200557.6
ADAM11
ADAM metallopeptidase domain 11
chr5_+_139493665 0.000 ENST00000331327.3
PURA
purine-rich element binding protein A
chr13_+_20532807 0.000 ENST00000382869.3
ENST00000382881.3
ZMYM2

zinc finger, MYM-type 2

chr2_-_213403565 0.000 ENST00000342788.4
ENST00000436443.1
ERBB4

v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4

chr6_+_146348782 0.000 ENST00000361719.2
ENST00000392299.2
GRM1

glutamate receptor, metabotropic 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0097237 autophagic cell death(GO:0048102) cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.1 0.4 GO:2000644 negative regulation of low-density lipoprotein particle clearance(GO:0010989) low-density lipoprotein particle receptor catabolic process(GO:0032802) regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.1 0.9 GO:0060123 regulation of growth hormone secretion(GO:0060123)
0.1 0.3 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.1 0.1 GO:0043537 regulation of endothelial cell proliferation(GO:0001936) negative regulation of endothelial cell proliferation(GO:0001937) negative regulation of endothelial cell migration(GO:0010596) negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0 0.3 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.3 GO:0035630 glycolate metabolic process(GO:0009441) bone mineralization involved in bone maturation(GO:0035630)
0.0 0.1 GO:0003289 septum primum development(GO:0003284) atrial septum primum morphogenesis(GO:0003289) embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.3 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.2 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.2 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.0 0.1 GO:2000078 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287) regulation of type B pancreatic cell development(GO:2000074) positive regulation of type B pancreatic cell development(GO:2000078)
0.0 0.2 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.0 0.2 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.4 GO:0006386 transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.4 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.2 GO:0060487 lung epithelial cell differentiation(GO:0060487)
0.0 0.1 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.2 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.0 GO:0008050 female courtship behavior(GO:0008050)
0.0 1.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.1 GO:0006622 protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0031213 RSF complex(GO:0031213)
0.1 0.3 GO:0042405 nuclear RNA export factor complex(GO:0042272) nuclear inclusion body(GO:0042405)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.3 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 0.1 GO:0097651 phosphatidylinositol 3-kinase complex, class IA(GO:0005943) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937) histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.2 GO:0031941 filamentous actin(GO:0031941)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.1 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.0 0.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.2 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.4 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0019211 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0008327 methyl-CpG binding(GO:0008327)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.