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Motif ID: GFI1

Z-value: 1.261

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr17_+_47448102	2.590	ENST00000576461.1	RP11-81K2.1	Uncharacterized protein
chr4_-_155533787	2.453	ENST00000407946.1 ENST00000405164.1 ENST00000336098.3 ENST00000393846.2 ENST00000404648.3 ENST00000443553.1	FGG	fibrinogen gamma chain
chr2_+_11696464	2.344	ENST00000234142.5	GREB1	growth regulation by estrogen in breast cancer 1
chr17_-_26694979	2.296	ENST00000438614.1	VTN	vitronectin
chr17_-_26695013	2.226	ENST00000555059.2	CTB-96E2.2	Homeobox protein SEBOX
chr14_-_22005062	1.914	ENST00000317492.5	SALL2	spalt-like transcription factor 2
chr6_+_31982539	1.731	ENST00000435363.2 ENST00000425700.2	C4B	complement component 4B (Chido blood group)
chr6_+_31949801	1.692	ENST00000428956.2 ENST00000498271.1	C4A	complement component 4A (Rodgers blood group)
chr14_-_22005343	1.547	ENST00000327430.3	SALL2	spalt-like transcription factor 2
chr17_+_1665253	1.493	ENST00000254722.4	SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chrX_+_49294472	1.478	ENST00000361446.5	GAGE12B	G antigen 12B
chr17_-_7018128	1.414	ENST00000380952.2 ENST00000254850.7	ASGR2	asialoglycoprotein receptor 2
chr17_-_7017968	1.397	ENST00000355035.5	ASGR2	asialoglycoprotein receptor 2
chr17_+_1665345	1.375	ENST00000576406.1 ENST00000571149.1	SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr8_-_145642267	1.354	ENST00000301305.3	SLC39A4	solute carrier family 39 (zinc transporter), member 4
chr11_+_22689648	1.235	ENST00000278187.3	GAS2	growth arrest-specific 2
chr8_-_145641864	1.202	ENST00000276833.5	SLC39A4	solute carrier family 39 (zinc transporter), member 4
chr17_+_4675175	1.098	ENST00000270560.3	TM4SF5	transmembrane 4 L six family member 5
chr17_-_79895097	1.065	ENST00000402252.2 ENST00000583564.1 ENST00000585244.1 ENST00000337943.5 ENST00000579698.1	PYCR1	pyrroline-5-carboxylate reductase 1
chr11_+_22688150	0.979	ENST00000454584.2	GAS2	growth arrest-specific 2
chr5_-_78809950	0.973	ENST00000334082.6	HOMER1	homer homolog 1 (Drosophila)
chr12_+_71833550	0.946	ENST00000266674.5	LGR5	leucine-rich repeat containing G protein-coupled receptor 5
chr20_-_33999766	0.910	ENST00000349714.5 ENST00000438533.1 ENST00000359226.2 ENST00000374384.2 ENST00000374377.5 ENST00000407996.2 ENST00000424405.1 ENST00000542501.1 ENST00000397554.1 ENST00000540457.1 ENST00000374380.2 ENST00000374385.5	UQCC1	ubiquinol-cytochrome c reductase complex assembly factor 1
chr1_-_110306562	0.886	ENST00000369805.3	EPS8L3	EPS8-like 3
chr7_-_87104963	0.886	ENST00000359206.3 ENST00000358400.3 ENST00000265723.4	ABCB4	ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr12_+_100867486	0.885	ENST00000548884.1	NR1H4	nuclear receptor subfamily 1, group H, member 4
chr16_+_82090028	0.861	ENST00000568090.1	HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2
chr17_-_56595196	0.825	ENST00000579921.1 ENST00000579925.1 ENST00000323456.5	MTMR4	myotubularin related protein 4
chr14_-_22005018	0.779	ENST00000546363.1	SALL2	spalt-like transcription factor 2
chr15_-_52587945	0.768	ENST00000443683.2 ENST00000558479.1 ENST00000261839.7	MYO5C	myosin VC
chr4_-_144940477	0.767	ENST00000513128.1 ENST00000429670.2 ENST00000502664.1	GYPB	glycophorin B (MNS blood group)
chr5_+_133451254	0.763	ENST00000517851.1 ENST00000521639.1 ENST00000522375.1 ENST00000378560.4 ENST00000432532.2 ENST00000520958.1 ENST00000518915.1 ENST00000395023.1	TCF7	transcription factor 7 (T-cell specific, HMG-box)
chr10_-_82049424	0.732	ENST00000372213.3	MAT1A	methionine adenosyltransferase I, alpha
chr4_-_145061788	0.727	ENST00000512064.1 ENST00000512789.1 ENST00000504786.1 ENST00000503627.1 ENST00000535709.1 ENST00000324022.10 ENST00000360771.4 ENST00000283126.7	GYPA GYPB	glycophorin A (MNS blood group) glycophorin B (MNS blood group)
chr6_+_42984723	0.707	ENST00000332245.8	KLHDC3	kelch domain containing 3
chr18_+_55711575	0.701	ENST00000356462.6 ENST00000400345.3 ENST00000589054.1 ENST00000256832.7	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr2_+_54683419	0.693	ENST00000356805.4	SPTBN1	spectrin, beta, non-erythrocytic 1
chr6_+_42584847	0.684	ENST00000372883.3	UBR2	ubiquitin protein ligase E3 component n-recognin 2
chr10_-_13523073	0.681	ENST00000440282.1	BEND7	BEN domain containing 7
chr13_-_46756351	0.681	ENST00000323076.2	LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr10_+_94451574	0.655	ENST00000492654.2	HHEX	hematopoietically expressed homeobox
chr10_-_11574274	0.644	ENST00000277575.5	USP6NL	USP6 N-terminal like
chr17_-_79895154	0.634	ENST00000405481.4 ENST00000585215.1 ENST00000577624.1 ENST00000403172.4	PYCR1	pyrroline-5-carboxylate reductase 1
chr12_+_100867694	0.631	ENST00000392986.3 ENST00000549996.1	NR1H4	nuclear receptor subfamily 1, group H, member 4
chr2_-_111291587	0.629	ENST00000437167.1	RGPD6	RANBP2-like and GRIP domain containing 6
chr2_+_17721920	0.628	ENST00000295156.4	VSNL1	visinin-like 1
chr7_-_71912046	0.591	ENST00000395276.2 ENST00000431984.1	CALN1	calneuron 1
chr1_-_25291475	0.588	ENST00000338888.3 ENST00000399916.1	RUNX3	runt-related transcription factor 3
chr1_+_46713404	0.585	ENST00000371975.4 ENST00000469835.1	RAD54L	RAD54-like (S. cerevisiae)
chr2_-_89157161	0.576	ENST00000390237.2	IGKC	immunoglobulin kappa constant
chr1_+_46713357	0.572	ENST00000442598.1	RAD54L	RAD54-like (S. cerevisiae)
chrX_+_48681768	0.571	ENST00000430858.1	HDAC6	histone deacetylase 6
chr19_-_13227534	0.557	ENST00000588229.1 ENST00000357720.4	TRMT1	tRNA methyltransferase 1 homolog (S. cerevisiae)
chr6_-_31704282	0.554	ENST00000375784.3 ENST00000375779.2	CLIC1	chloride intracellular channel 1
chr7_-_23510086	0.540	ENST00000258729.3	IGF2BP3	insulin-like growth factor 2 mRNA binding protein 3
chr19_-_13227463	0.532	ENST00000437766.1 ENST00000221504.8	TRMT1	tRNA methyltransferase 1 homolog (S. cerevisiae)
chr1_+_156338993	0.531	ENST00000368249.1 ENST00000368246.2 ENST00000537040.1 ENST00000400992.2 ENST00000255013.3 ENST00000451864.2	RHBG	Rh family, B glycoprotein (gene/pseudogene)
chr7_-_1980128	0.528	ENST00000437877.1	MAD1L1	MAD1 mitotic arrest deficient-like 1 (yeast)
chr5_+_118690466	0.526	ENST00000503646.1	TNFAIP8	tumor necrosis factor, alpha-induced protein 8
chrX_-_48056199	0.523	ENST00000311798.1 ENST00000347757.1	SSX5	synovial sarcoma, X breakpoint 5
chr16_-_70323422	0.523	ENST00000261772.8	AARS	alanyl-tRNA synthetase
chr3_-_66024213	0.518	ENST00000483466.1	MAGI1	membrane associated guanylate kinase, WW and PDZ domain containing 1
chr17_-_56494908	0.518	ENST00000577716.1	RNF43	ring finger protein 43
chr3_-_178976996	0.516	ENST00000485523.1	KCNMB3	potassium large conductance calcium-activated channel, subfamily M beta member 3
chr4_-_144826682	0.514	ENST00000358615.4 ENST00000437468.2	GYPE	glycophorin E (MNS blood group)
chr16_+_12059050	0.508	ENST00000396495.3	TNFRSF17	tumor necrosis factor receptor superfamily, member 17
chr17_-_56494882	0.507	ENST00000584437.1	RNF43	ring finger protein 43
chr16_+_12059091	0.506	ENST00000562385.1	TNFRSF17	tumor necrosis factor receptor superfamily, member 17
chr2_-_96874553	0.499	ENST00000337288.5 ENST00000443962.1	STARD7	StAR-related lipid transfer (START) domain containing 7
chr2_+_62900986	0.487	ENST00000405015.3 ENST00000413434.1 ENST00000426940.1 ENST00000449820.1	EHBP1	EH domain binding protein 1
chr1_-_67142710	0.478	ENST00000502413.2	AL139147.1	Uncharacterized protein
chr6_-_41040268	0.466	ENST00000373154.2 ENST00000244558.9 ENST00000464633.1 ENST00000424266.2 ENST00000479950.1 ENST00000482515.1	OARD1	O-acyl-ADP-ribose deacylase 1
chrX_-_102319092	0.461	ENST00000372728.3	BEX1	brain expressed, X-linked 1
chr5_+_157158205	0.460	ENST00000231198.7	THG1L	tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr16_+_12058961	0.455	ENST00000053243.1	TNFRSF17	tumor necrosis factor receptor superfamily, member 17
chr19_+_6772710	0.453	ENST00000304076.2 ENST00000602142.1 ENST00000596764.1	VAV1	vav 1 guanine nucleotide exchange factor
chr6_+_45296048	0.451	ENST00000465038.2 ENST00000352853.5 ENST00000541979.1 ENST00000371438.1	RUNX2	runt-related transcription factor 2
chr3_-_33686743	0.451	ENST00000333778.6 ENST00000539981.1	CLASP2	cytoplasmic linker associated protein 2
chr2_+_17721230	0.444	ENST00000457525.1	VSNL1	visinin-like 1
chrX_-_52683950	0.444	ENST00000298181.5	SSX7	synovial sarcoma, X breakpoint 7
chr17_-_56494713	0.421	ENST00000407977.2	RNF43	ring finger protein 43
chr14_-_95623607	0.419	ENST00000531162.1 ENST00000529720.1 ENST00000343455.3	DICER1	dicer 1, ribonuclease type III
chr2_-_27938593	0.418	ENST00000379677.2	AC074091.13	Uncharacterized protein
chr14_-_95624227	0.418	ENST00000526495.1	DICER1	dicer 1, ribonuclease type III
chr4_-_89744457	0.414	ENST00000395002.2	FAM13A	family with sequence similarity 13, member A
chr1_-_173793246	0.413	ENST00000345664.6 ENST00000367710.3	CENPL	centromere protein L
chrX_+_12885183	0.412	ENST00000380659.3	TLR7	toll-like receptor 7
chr9_+_108456800	0.410	ENST00000434214.1 ENST00000374692.3	TMEM38B	transmembrane protein 38B
chr1_-_173793458	0.410	ENST00000356198.2	CENPL	centromere protein L
chr7_+_112063192	0.410	ENST00000005558.4	IFRD1	interferon-related developmental regulator 1
chr1_-_160681593	0.409	ENST00000368045.3 ENST00000368046.3	CD48	CD48 molecule
chr6_+_6588902	0.409	ENST00000230568.4	LY86	lymphocyte antigen 86
chr8_+_40010989	0.406	ENST00000315792.3	C8orf4	chromosome 8 open reading frame 4
chr17_+_76311791	0.403	ENST00000586321.1	AC061992.2	AC061992.2
chr11_-_66675371	0.401	ENST00000393955.2	PC	pyruvate carboxylase
chr10_-_65028938	0.397	ENST00000402544.1	JMJD1C	jumonji domain containing 1C
chr11_+_117049854	0.396	ENST00000278951.7	SIDT2	SID1 transmembrane family, member 2
chr2_+_47630108	0.391	ENST00000233146.2 ENST00000454849.1 ENST00000543555.1	MSH2	mutS homolog 2
chr21_+_44313375	0.390	ENST00000354250.2 ENST00000340344.4	NDUFV3	NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa
chr17_-_18266660	0.389	ENST00000582653.1 ENST00000352886.6	SHMT1	serine hydroxymethyltransferase 1 (soluble)
chr6_-_25930904	0.380	ENST00000377850.3	SLC17A2	solute carrier family 17, member 2
chr17_-_18266765	0.377	ENST00000354098.3	SHMT1	serine hydroxymethyltransferase 1 (soluble)
chr4_-_89744365	0.373	ENST00000513837.1 ENST00000503556.1	FAM13A	family with sequence similarity 13, member A
chr9_+_133710453	0.371	ENST00000318560.5	ABL1	c-abl oncogene 1, non-receptor tyrosine kinase
chr17_-_18266797	0.370	ENST00000316694.3 ENST00000539052.1	SHMT1	serine hydroxymethyltransferase 1 (soluble)
chr10_-_65028817	0.370	ENST00000542921.1	JMJD1C	jumonji domain containing 1C
chr5_+_59783941	0.367	ENST00000506884.1 ENST00000504876.2	PART1	prostate androgen-regulated transcript 1 (non-protein coding)
chr3_-_142166904	0.367	ENST00000264951.4	XRN1	5'-3' exoribonuclease 1
chr12_-_56756553	0.365	ENST00000398189.3 ENST00000541105.1	APOF	apolipoprotein F
chr1_-_155947951	0.363	ENST00000313695.7 ENST00000497907.1	ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr19_+_50353944	0.363	ENST00000594151.1 ENST00000600603.1 ENST00000601638.1 ENST00000221557.9	PTOV1	prostate tumor overexpressed 1
chr8_+_21823726	0.362	ENST00000433566.4	XPO7	exportin 7
chr3_+_51575596	0.362	ENST00000409535.2	RAD54L2	RAD54-like 2 (S. cerevisiae)
chr1_+_32739733	0.362	ENST00000333070.4	LCK	lymphocyte-specific protein tyrosine kinase
chr7_-_148581251	0.358	ENST00000478654.1 ENST00000460911.1 ENST00000350995.2	EZH2	enhancer of zeste homolog 2 (Drosophila)
chr20_+_36373032	0.356	ENST00000373473.1	CTNNBL1	catenin, beta like 1
chrX_+_37639302	0.356	ENST00000545017.1 ENST00000536160.1	CYBB	cytochrome b-245, beta polypeptide
chr12_+_56732658	0.356	ENST00000228534.4	IL23A	interleukin 23, alpha subunit p19
chr11_-_72432950	0.356	ENST00000426523.1 ENST00000429686.1	ARAP1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr6_-_41040195	0.356	ENST00000463088.1 ENST00000469104.1 ENST00000486443.1	OARD1	O-acyl-ADP-ribose deacylase 1
chr7_+_55980331	0.354	ENST00000429591.2	ZNF713	zinc finger protein 713
chr14_-_37642016	0.354	ENST00000331299.5	SLC25A21	solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
chr7_+_130020932	0.347	ENST00000484324.1	CPA1	carboxypeptidase A1 (pancreatic)
chr7_+_100136811	0.346	ENST00000300176.4 ENST00000262935.4	AGFG2	ArfGAP with FG repeats 2
chr3_+_63898275	0.345	ENST00000538065.1	ATXN7	ataxin 7
chr12_-_56843161	0.341	ENST00000554616.1 ENST00000553532.1 ENST00000229201.4	TIMELESS	timeless circadian clock
chr6_-_135271260	0.340	ENST00000265605.2	ALDH8A1	aldehyde dehydrogenase 8 family, member A1
chr11_+_117049445	0.338	ENST00000324225.4 ENST00000532960.1	SIDT2	SID1 transmembrane family, member 2
chr6_-_32920794	0.338	ENST00000395305.3 ENST00000395303.3 ENST00000374843.4 ENST00000429234.1	HLA-DMA XXbac-BPG181M17.5	major histocompatibility complex, class II, DM alpha Uncharacterized protein
chr8_-_27115903	0.334	ENST00000350889.4 ENST00000519997.1 ENST00000519614.1 ENST00000522908.1 ENST00000265770.7	STMN4	stathmin-like 4
chr5_+_59783540	0.331	ENST00000515734.2	PART1	prostate androgen-regulated transcript 1 (non-protein coding)
chr2_+_152214098	0.329	ENST00000243347.3	TNFAIP6	tumor necrosis factor, alpha-induced protein 6
chr2_-_153574480	0.327	ENST00000410080.1	PRPF40A	PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr4_-_89744314	0.322	ENST00000508369.1	FAM13A	family with sequence similarity 13, member A
chr6_+_167704838	0.320	ENST00000366829.2	UNC93A	unc-93 homolog A (C. elegans)
chr4_+_41937131	0.317	ENST00000504986.1 ENST00000508448.1 ENST00000513702.1 ENST00000325094.5	TMEM33	transmembrane protein 33
chr12_+_117176113	0.316	ENST00000319176.7	RNFT2	ring finger protein, transmembrane 2
chr8_-_27115931	0.313	ENST00000523048.1	STMN4	stathmin-like 4
chr19_+_50354430	0.312	ENST00000599732.1	PTOV1	prostate tumor overexpressed 1
chr5_+_176784837	0.311	ENST00000408923.3	RGS14	regulator of G-protein signaling 14
chr20_+_45338126	0.309	ENST00000359271.2	SLC2A10	solute carrier family 2 (facilitated glucose transporter), member 10
chr7_-_140482926	0.309	ENST00000496384.2	BRAF	v-raf murine sarcoma viral oncogene homolog B
chr17_-_40761375	0.308	ENST00000543197.1 ENST00000309428.5	FAM134C	family with sequence similarity 134, member C
chr20_-_34252759	0.307	ENST00000414711.1 ENST00000416778.1 ENST00000397442.1 ENST00000440240.1 ENST00000412056.1 ENST00000352393.4 ENST00000458038.1 ENST00000420363.1 ENST00000434795.1 ENST00000437100.1 ENST00000414664.1 ENST00000359646.1 ENST00000424458.1 ENST00000374104.3 ENST00000374114.3	CPNE1 RBM12	copine I RNA binding motif protein 12
chr7_+_150758304	0.306	ENST00000482950.1 ENST00000463414.1 ENST00000310317.5	SLC4A2	solute carrier family 4 (anion exchanger), member 2
chr19_-_15529790	0.305	ENST00000596195.1 ENST00000595067.1 ENST00000595465.2 ENST00000397410.5 ENST00000600247.1	AKAP8L	A kinase (PRKA) anchor protein 8-like
chr1_+_168250194	0.303	ENST00000367821.3	TBX19	T-box 19
chr3_+_52017454	0.299	ENST00000476854.1 ENST00000476351.1 ENST00000494103.1 ENST00000404366.2 ENST00000469863.1	ACY1	aminoacylase 1
chr19_+_50354462	0.298	ENST00000601675.1	PTOV1	prostate tumor overexpressed 1
chr5_-_147162078	0.296	ENST00000507386.1	JAKMIP2	janus kinase and microtubule interacting protein 2
chr2_-_68479614	0.293	ENST00000234310.3	PPP3R1	protein phosphatase 3, regulatory subunit B, alpha
chr2_-_238499725	0.290	ENST00000264601.3	RAB17	RAB17, member RAS oncogene family
chr4_+_106631966	0.288	ENST00000360505.5 ENST00000510865.1 ENST00000509336.1	GSTCD	glutathione S-transferase, C-terminal domain containing
chr2_-_158300556	0.287	ENST00000264192.3	CYTIP	cytohesin 1 interacting protein
chr10_-_74385811	0.283	ENST00000603011.1 ENST00000401998.3 ENST00000361114.5 ENST00000604238.1	MICU1	mitochondrial calcium uptake 1
chr19_+_3880581	0.281	ENST00000450849.2 ENST00000301260.6 ENST00000398448.3	ATCAY	ataxia, cerebellar, Cayman type
chr5_-_111091948	0.280	ENST00000447165.2	NREP	neuronal regeneration related protein
chr6_+_6588316	0.278	ENST00000379953.2	LY86	lymphocyte antigen 86
chr15_+_84115868	0.276	ENST00000427482.2	SH3GL3	SH3-domain GRB2-like 3
chr7_-_148581360	0.275	ENST00000320356.2 ENST00000541220.1 ENST00000483967.1 ENST00000536783.1	EZH2	enhancer of zeste homolog 2 (Drosophila)
chr18_-_19283649	0.274	ENST00000584464.1 ENST00000578270.1	ABHD3	abhydrolase domain containing 3
chr11_-_72433346	0.272	ENST00000334211.8	ARAP1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr6_+_111195973	0.266	ENST00000368885.3 ENST00000368882.3 ENST00000451850.2 ENST00000368877.5	AMD1	adenosylmethionine decarboxylase 1
chr16_+_31366536	0.265	ENST00000562522.1	ITGAX	integrin, alpha X (complement component 3 receptor 4 subunit)
chr2_+_171785012	0.261	ENST00000234160.4	GORASP2	golgi reassembly stacking protein 2, 55kDa
chr6_-_135271219	0.261	ENST00000367847.2 ENST00000367845.2	ALDH8A1	aldehyde dehydrogenase 8 family, member A1
chr14_+_72052983	0.260	ENST00000358550.2	SIPA1L1	signal-induced proliferation-associated 1 like 1
chr17_+_34171081	0.258	ENST00000585577.1	TAF15	TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
chr2_+_202122703	0.257	ENST00000447616.1 ENST00000358485.4	CASP8	caspase 8, apoptosis-related cysteine peptidase
chr10_+_31610064	0.251	ENST00000446923.2 ENST00000559476.1	ZEB1	zinc finger E-box binding homeobox 1
chr6_-_32908792	0.250	ENST00000418107.2	HLA-DMB	major histocompatibility complex, class II, DM beta
chr7_+_123488124	0.248	ENST00000476325.1	HYAL4	hyaluronoglucosaminidase 4
chr12_+_7941989	0.245	ENST00000229307.4	NANOG	Nanog homeobox
chr19_-_16045220	0.244	ENST00000326742.8	CYP4F11	cytochrome P450, family 4, subfamily F, polypeptide 11
chrX_-_48216101	0.244	ENST00000298396.2 ENST00000376893.3	SSX3	synovial sarcoma, X breakpoint 3
chr5_+_37379314	0.243	ENST00000265107.4 ENST00000504564.1	WDR70	WD repeat domain 70
chr2_+_32853093	0.242	ENST00000448773.1 ENST00000317907.4	TTC27	tetratricopeptide repeat domain 27
chr15_+_84116106	0.239	ENST00000535412.1 ENST00000324537.5	SH3GL3	SH3-domain GRB2-like 3
chr19_-_46088068	0.234	ENST00000263275.4 ENST00000323060.3	OPA3	optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr12_+_96252706	0.233	ENST00000266735.5 ENST00000553192.1 ENST00000552085.1	SNRPF	small nuclear ribonucleoprotein polypeptide F
chr5_-_88179302	0.230	ENST00000504921.2	MEF2C	myocyte enhancer factor 2C
chr11_+_117049910	0.227	ENST00000431081.2 ENST00000524842.1	SIDT2	SID1 transmembrane family, member 2
chr17_+_45728427	0.226	ENST00000540627.1	KPNB1	karyopherin (importin) beta 1
chr16_+_19183671	0.225	ENST00000562711.2	SYT17	synaptotagmin XVII
chr9_+_2159850	0.224	ENST00000416751.1	SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr19_+_47813110	0.219	ENST00000355085.3	C5AR1	complement component 5a receptor 1
chr17_-_3539558	0.214	ENST00000225519.3	SHPK	sedoheptulokinase
chr1_+_12524965	0.213	ENST00000471923.1	VPS13D	vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr16_-_67517716	0.210	ENST00000290953.2	AGRP	agouti related protein homolog (mouse)
chr8_+_75736761	0.209	ENST00000260113.2	PI15	peptidase inhibitor 15
chr19_+_50354393	0.204	ENST00000391842.1	PTOV1	prostate tumor overexpressed 1
chr6_+_28092338	0.203	ENST00000340487.4	ZSCAN16	zinc finger and SCAN domain containing 16
chr19_-_51875523	0.203	ENST00000593572.1 ENST00000595157.1	NKG7	natural killer cell group 7 sequence
chr14_-_106069247	0.202	ENST00000479229.1	RP11-731F5.1	RP11-731F5.1
chr8_+_145192672	0.197	ENST00000347708.4	FAM203A	family with sequence similarity 203, member A
chr16_-_19729502	0.197	ENST00000219837.7	KNOP1	lysine-rich nucleolar protein 1
chr14_+_35591858	0.197	ENST00000603544.1	KIAA0391	KIAA0391
chr20_-_33732952	0.196	ENST00000541621.1	EDEM2	ER degradation enhancer, mannosidase alpha-like 2
chr2_-_153573887	0.195	ENST00000493468.2 ENST00000545856.1	PRPF40A	PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr11_-_11374904	0.195	ENST00000528848.2	CSNK2A3	casein kinase 2, alpha 3 polypeptide

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	2.3	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.6	2.9	GO:0007614	short-term memory(GO:0007614)
0.3	1.0	GO:0007206	phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.2	2.9	GO:0055069	cellular zinc ion homeostasis(GO:0006882) zinc ion homeostasis(GO:0055069)
0.2	1.7	GO:0006561	proline biosynthetic process(GO:0006561)
0.2	0.8	GO:0031643	regulation of Schwann cell differentiation(GO:0014038) positive regulation of Schwann cell differentiation(GO:0014040) positive regulation of myelination(GO:0031643)
0.2	0.6	GO:0090034	regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.2	0.7	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.2	0.7	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.2	0.5	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.2	0.5	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.2	0.7	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.2	1.1	GO:0019264	L-serine catabolic process(GO:0006565) glycine biosynthetic process from serine(GO:0019264)
0.2	0.6	GO:0030037	actin filament reorganization involved in cell cycle(GO:0030037) actin filament reorganization(GO:0090527)
0.1	0.7	GO:0007182	common-partner SMAD protein phosphorylation(GO:0007182)
0.1	0.4	GO:0007518	myoblast fate determination(GO:0007518)
0.1	0.6	GO:0042905	retinal metabolic process(GO:0042574) 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1	0.6	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
0.1	0.4	GO:0060025	regulation of synaptic activity(GO:0060025)
0.1	0.4	GO:0010520	regulation of reciprocal meiotic recombination(GO:0010520) regulation of meiosis I(GO:0060631)
0.1	0.4	GO:0045356	positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1	0.7	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.1	0.2	GO:0000212	meiotic spindle organization(GO:0000212)
0.1	0.8	GO:0071353	cellular response to interleukin-4(GO:0071353)
0.1	0.4	GO:0071025	RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.1	0.3	GO:0006597	spermine biosynthetic process(GO:0006597)
0.1	0.5	GO:0000089	mitotic metaphase(GO:0000089)
0.1	0.2	GO:0051083	'de novo' cotranslational protein folding(GO:0051083)
0.1	0.4	GO:0002051	osteoblast fate commitment(GO:0002051)
0.1	0.4	GO:0051140	tyrosine phosphorylation of Stat4 protein(GO:0042504) regulation of tyrosine phosphorylation of Stat4 protein(GO:0042519) positive regulation of tyrosine phosphorylation of Stat4 protein(GO:0042520) regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.1	0.6	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1	4.0	GO:0006958	complement activation, classical pathway(GO:0006958)
0.1	0.7	GO:0007141	male meiosis I(GO:0007141)
0.1	0.1	GO:0030223	neutrophil differentiation(GO:0030223)
0.1	0.3	GO:0060259	regulation of feeding behavior(GO:0060259)
0.1	0.2	GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.1	0.2	GO:0060209	estrus(GO:0060209)
0.1	0.8	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.1	GO:0045475	locomotor rhythm(GO:0045475)
0.0	0.5	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	1.5	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	0.2	GO:0071436	sodium ion export(GO:0071436)
0.0	0.3	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.0	0.2	GO:0001575	globoside metabolic process(GO:0001575)
0.0	0.1	GO:0090274	positive regulation of somatostatin secretion(GO:0090274)
0.0	0.5	GO:0019228	neuronal action potential(GO:0019228)
0.0	0.2	GO:0071294	cellular response to zinc ion(GO:0071294)
0.0	0.2	GO:0010759	regulation of macrophage chemotaxis(GO:0010758) positive regulation of macrophage chemotaxis(GO:0010759)
0.0	0.9	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.0	0.4	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.1	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0	0.5	GO:0006400	tRNA modification(GO:0006400)
0.0	0.2	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.2	GO:0019985	translesion synthesis(GO:0019985)
0.0	2.7	GO:0055088	lipid homeostasis(GO:0055088)
0.0	0.1	GO:0002384	hepatic immune response(GO:0002384)
0.0	0.4	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.0	0.1	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.0	1.6	GO:0008033	tRNA processing(GO:0008033)
0.0	0.3	GO:0097061	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.1	GO:0006216	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0	0.5	GO:0007020	microtubule nucleation(GO:0007020)
0.0	0.3	GO:0060487	lung epithelial cell differentiation(GO:0060487)
0.0	1.3	GO:0008206	bile acid metabolic process(GO:0008206)
0.0	0.1	GO:0061198	fungiform papilla development(GO:0061196) fungiform papilla morphogenesis(GO:0061197) fungiform papilla formation(GO:0061198)
0.0	0.1	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0	0.1	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.2	GO:0003148	outflow tract septum morphogenesis(GO:0003148)
0.0	2.1	GO:0051592	response to calcium ion(GO:0051592)
0.0	0.9	GO:0000725	double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0	0.1	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.0	0.2	GO:0035019	somatic stem cell population maintenance(GO:0035019)
0.0	0.7	GO:0007131	reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0	0.1	GO:0002125	maternal aggressive behavior(GO:0002125) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) hyperosmotic salinity response(GO:0042538) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0	0.2	GO:0006027	glycosaminoglycan catabolic process(GO:0006027)
0.0	0.1	GO:0061303	cornea development in camera-type eye(GO:0061303)
0.0	1.9	GO:0008360	regulation of cell shape(GO:0008360)
0.0	0.4	GO:0045730	respiratory burst(GO:0045730)
0.0	0.1	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0	0.7	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.0	0.1	GO:0032817	regulation of natural killer cell proliferation(GO:0032817)
0.0	0.4	GO:0071804	cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0	0.3	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.2	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.1	GO:0048935	peripheral nervous system neuron development(GO:0048935)
0.0	0.0	GO:0048865	stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0	0.0	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0	0.9	GO:0032526	response to retinoic acid(GO:0032526)
0.0	0.1	GO:0003097	renal water transport(GO:0003097) renal water absorption(GO:0070295)
0.0	0.1	GO:0030903	notochord development(GO:0030903)
0.0	0.1	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0	0.3	GO:0034612	response to tumor necrosis factor(GO:0034612)
0.0	0.2	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0001660	fever generation(GO:0001660)
0.0	0.1	GO:0045086	positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0	0.1	GO:0000090	mitotic anaphase(GO:0000090)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	2.3	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.2	2.5	GO:0005577	fibrinogen complex(GO:0005577)
0.1	0.4	GO:0032009	early phagosome(GO:0032009)
0.1	0.4	GO:0032302	MutSbeta complex(GO:0032302)
0.1	0.9	GO:0046581	intercellular canaliculus(GO:0046581)
0.1	0.7	GO:0001891	phagocytic cup(GO:0001891)
0.1	2.6	GO:0055038	recycling endosome membrane(GO:0055038)
0.1	0.8	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1	0.3	GO:0005955	calcineurin complex(GO:0005955)
0.1	0.7	GO:0008091	spectrin(GO:0008091)
0.1	0.5	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.1	0.2	GO:0043219	lateral loop(GO:0043219)
0.0	0.5	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.9	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.6	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.8	GO:0043034	costamere(GO:0043034)
0.0	0.6	GO:0016235	aggresome(GO:0016235)
0.0	0.5	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.4	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.2	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.3	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	1.4	GO:0005884	actin filament(GO:0005884)
0.0	0.2	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0005687	U4 snRNP(GO:0005687)
0.0	3.1	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	0.4	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.4	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.4	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.0	1.4	GO:0016363	nuclear matrix(GO:0016363)
0.0	0.8	GO:0005903	brush border(GO:0005903)
0.0	0.6	GO:0098636	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.1	GO:0043202	lysosomal lumen(GO:0043202)
0.0	2.2	GO:0005925	focal adhesion(GO:0005925)
0.0	0.1	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.1	GO:0016234	inclusion body(GO:0016234)
0.0	1.1	GO:0070160	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.1	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.3	1.7	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.3	2.8	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.2	0.9	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.2	0.9	GO:0047006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.2	0.8	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.2	2.3	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2	0.5	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.2	0.7	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.2	1.1	GO:0008732	glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.2	0.5	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.1	0.6	GO:0042903	tubulin deacetylase activity(GO:0042903)
0.1	0.4	GO:0000404	heteroduplex DNA loop binding(GO:0000404) double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.1	0.4	GO:0042610	CD8 receptor binding(GO:0042610)
0.1	0.7	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.1	2.6	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.1	2.5	GO:0043499	obsolete eukaryotic cell surface binding(GO:0043499)
0.1	1.5	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.1	0.8	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1	0.4	GO:0035197	siRNA binding(GO:0035197)
0.1	1.5	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.1	0.5	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	0.5	GO:0030506	ankyrin binding(GO:0030506)
0.1	0.6	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	0.3	GO:0004723	calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.1	0.4	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.1	0.5	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.1	0.4	GO:0005310	dicarboxylic acid transmembrane transporter activity(GO:0005310)
0.1	0.4	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.1	1.0	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.3	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.3	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.1	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.0	0.3	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.4	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.1	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0	0.4	GO:0009374	biotin binding(GO:0009374)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.1	GO:0004951	cholecystokinin receptor activity(GO:0004951)
0.0	0.1	GO:0008267	poly-glutamine tract binding(GO:0008267)
0.0	0.3	GO:0005402	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) D-glucose transmembrane transporter activity(GO:0055056)
0.0	0.4	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0004074	biliverdin reductase activity(GO:0004074)
0.0	0.1	GO:0019981	interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0	0.2	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.6	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.2	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.3	GO:0015301	anion:anion antiporter activity(GO:0015301)
0.0	0.4	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	5.4	GO:0030414	peptidase inhibitor activity(GO:0030414)
0.0	0.1	GO:0030621	U4 snRNA binding(GO:0030621)
0.0	0.2	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	0.5	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.2	GO:0005436	sodium:phosphate symporter activity(GO:0005436)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.2	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.3	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.5	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.1	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0	0.0	GO:0034594	phosphatidylinositol trisphosphate phosphatase activity(GO:0034594)
0.0	0.2	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.2	GO:0032451	demethylase activity(GO:0032451)
0.0	0.2	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.2	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.1	GO:0004396	hexokinase activity(GO:0004396)
0.0	0.4	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.2	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.1	GO:0030280	structural constituent of epidermis(GO:0030280)
0.0	0.1	GO:0004447	iodide peroxidase activity(GO:0004447)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.4	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	0.6	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
0.0	0.3	GO:0070330	aromatase activity(GO:0070330)
0.0	0.2	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.3	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.0	0.1	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.1	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.3	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.1	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.1	GO:0030249	guanylate cyclase regulator activity(GO:0030249)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.4	SA_FAS_SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.3	ST_G_ALPHA_S_PATHWAY	G alpha s Pathway
0.0	0.5	SA_B_CELL_RECEPTOR_COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.

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