Motif ID: GGAAUGU
Z-value: 1.380
Mature miRNA associated with seed GGAAUGU:
Name | miRBase Accession |
---|---|
hsa-miR-1-3p | MIMAT0000416 |
hsa-miR-206 | MIMAT0000462 |
hsa-miR-613 | MIMAT0003281 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 3.9 | GO:0014029 | neural crest formation(GO:0014029) neural crest cell fate commitment(GO:0014034) convergent extension involved in axis elongation(GO:0060028) cellular response to prostaglandin E stimulus(GO:0071380) response to heparin(GO:0071503) cellular response to heparin(GO:0071504) negative regulation of non-canonical Wnt signaling pathway(GO:2000051) |
0.7 | 3.0 | GO:0051503 | purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) |
0.5 | 1.6 | GO:0010757 | negative regulation of plasminogen activation(GO:0010757) |
0.4 | 1.3 | GO:0030205 | dermatan sulfate metabolic process(GO:0030205) dermatan sulfate biosynthetic process(GO:0030208) |
0.3 | 2.0 | GO:0060414 | aorta development(GO:0035904) aorta morphogenesis(GO:0035909) aorta smooth muscle tissue morphogenesis(GO:0060414) |
0.3 | 0.8 | GO:0006740 | NADPH regeneration(GO:0006740) |
0.2 | 0.7 | GO:0060054 | positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054) |
0.2 | 1.4 | GO:0007499 | ectoderm and mesoderm interaction(GO:0007499) |
0.2 | 1.0 | GO:0051045 | negative regulation of membrane protein ectodomain proteolysis(GO:0051045) |
0.2 | 0.6 | GO:0042759 | fatty acid elongation, saturated fatty acid(GO:0019367) long-chain fatty acid biosynthetic process(GO:0042759) |
0.2 | 0.2 | GO:0060024 | rhythmic synaptic transmission(GO:0060024) |
0.2 | 0.5 | GO:0016081 | synaptic vesicle docking(GO:0016081) calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
0.2 | 1.0 | GO:0007500 | mesodermal cell fate determination(GO:0007500) |
0.2 | 1.4 | GO:0060666 | dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666) |
0.1 | 1.3 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
0.1 | 1.8 | GO:0050872 | white fat cell differentiation(GO:0050872) |
0.1 | 0.8 | GO:0043268 | positive regulation of potassium ion transport(GO:0043268) |
0.1 | 1.4 | GO:0001945 | lymph vessel development(GO:0001945) |
0.1 | 0.8 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
0.1 | 0.4 | GO:0031340 | positive regulation of vesicle fusion(GO:0031340) |
0.1 | 0.3 | GO:0001757 | somite specification(GO:0001757) |
0.1 | 0.4 | GO:0033197 | response to vitamin E(GO:0033197) |
0.1 | 0.6 | GO:0006880 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
0.1 | 0.2 | GO:0034770 | histone H4-K20 methylation(GO:0034770) |
0.1 | 0.3 | GO:0051409 | response to nitrosative stress(GO:0051409) |
0.1 | 0.2 | GO:0005997 | xylulose metabolic process(GO:0005997) |
0.1 | 0.5 | GO:0008354 | germ cell migration(GO:0008354) |
0.1 | 0.2 | GO:0018377 | N-terminal protein myristoylation(GO:0006499) protein myristoylation(GO:0018377) |
0.1 | 0.4 | GO:0007256 | activation of JNKK activity(GO:0007256) |
0.1 | 0.2 | GO:0046102 | nicotinamide riboside catabolic process(GO:0006738) inosine metabolic process(GO:0046102) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638) |
0.1 | 0.3 | GO:0006930 | substrate-dependent cell migration, cell extension(GO:0006930) |
0.1 | 0.5 | GO:0046835 | carbohydrate phosphorylation(GO:0046835) |
0.1 | 0.4 | GO:0042989 | sequestering of actin monomers(GO:0042989) |
0.0 | 0.2 | GO:0021527 | spinal cord association neuron differentiation(GO:0021527) |
0.0 | 0.1 | GO:0007538 | primary sex determination(GO:0007538) |
0.0 | 0.3 | GO:0006477 | protein sulfation(GO:0006477) |
0.0 | 0.1 | GO:0060318 | definitive erythrocyte differentiation(GO:0060318) |
0.0 | 0.3 | GO:0046325 | negative regulation of glucose import(GO:0046325) |
0.0 | 0.2 | GO:0043116 | negative regulation of vascular permeability(GO:0043116) |
0.0 | 0.1 | GO:0032119 | sequestering of zinc ion(GO:0032119) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) regulation of sequestering of zinc ion(GO:0061088) |
0.0 | 0.2 | GO:0034204 | Cdc42 protein signal transduction(GO:0032488) lipid translocation(GO:0034204) phospholipid translocation(GO:0045332) |
0.0 | 0.5 | GO:0034405 | response to fluid shear stress(GO:0034405) |
0.0 | 0.1 | GO:1904358 | positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358) |
0.0 | 0.3 | GO:0006621 | protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437) |
0.0 | 0.1 | GO:0010508 | positive regulation of autophagy(GO:0010508) |
0.0 | 0.1 | GO:0061298 | progesterone secretion(GO:0042701) retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299) |
0.0 | 0.1 | GO:0046469 | layer formation in cerebral cortex(GO:0021819) platelet activating factor metabolic process(GO:0046469) |
0.0 | 0.0 | GO:0097576 | autophagosome maturation(GO:0097352) vacuole fusion(GO:0097576) |
0.0 | 0.2 | GO:0002553 | histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553) |
0.0 | 0.3 | GO:0043113 | receptor clustering(GO:0043113) |
0.0 | 0.3 | GO:0045047 | protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599) |
0.0 | 0.6 | GO:0048009 | insulin-like growth factor receptor signaling pathway(GO:0048009) |
0.0 | 0.2 | GO:0060158 | neuron remodeling(GO:0016322) regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932) phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
0.0 | 0.1 | GO:0060009 | Sertoli cell development(GO:0060009) |
0.0 | 0.1 | GO:0002036 | regulation of L-glutamate transport(GO:0002036) |
0.0 | 0.1 | GO:0051927 | obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927) |
0.0 | 0.2 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
0.0 | 0.5 | GO:0015813 | L-glutamate transport(GO:0015813) |
0.0 | 0.1 | GO:0035434 | copper ion transmembrane transport(GO:0035434) |
0.0 | 0.4 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
0.0 | 0.4 | GO:0006829 | zinc II ion transport(GO:0006829) |
0.0 | 0.1 | GO:0048388 | endosomal lumen acidification(GO:0048388) |
0.0 | 0.0 | GO:0010996 | mechanosensory behavior(GO:0007638) response to auditory stimulus(GO:0010996) operant conditioning(GO:0035106) |
0.0 | 0.3 | GO:0005513 | detection of calcium ion(GO:0005513) |
0.0 | 0.4 | GO:0034199 | activation of protein kinase A activity(GO:0034199) |
0.0 | 1.3 | GO:0008064 | regulation of actin polymerization or depolymerization(GO:0008064) |
0.0 | 0.3 | GO:0006376 | mRNA splice site selection(GO:0006376) |
0.0 | 0.0 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
0.0 | 0.0 | GO:0010544 | regulation of phosphatidylinositol biosynthetic process(GO:0010511) negative regulation of platelet activation(GO:0010544) regulation of phospholipid biosynthetic process(GO:0071071) |
0.0 | 0.1 | GO:0006906 | vesicle fusion(GO:0006906) |
0.0 | 0.1 | GO:0061339 | establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339) |
0.0 | 0.9 | GO:0006939 | smooth muscle contraction(GO:0006939) |
0.0 | 0.2 | GO:0030201 | heparan sulfate proteoglycan metabolic process(GO:0030201) |
0.0 | 0.1 | GO:0046519 | sphingoid metabolic process(GO:0046519) |
0.0 | 0.0 | GO:0060124 | positive regulation of growth hormone secretion(GO:0060124) |
0.0 | 0.7 | GO:0031668 | cellular response to extracellular stimulus(GO:0031668) |
0.0 | 0.3 | GO:0080171 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 3.0 | GO:0005916 | fascia adherens(GO:0005916) |
0.2 | 0.5 | GO:0070044 | synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044) |
0.2 | 0.5 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
0.1 | 1.6 | GO:0005577 | fibrinogen complex(GO:0005577) |
0.1 | 0.3 | GO:0060201 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
0.0 | 0.3 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
0.0 | 0.1 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
0.0 | 0.2 | GO:0042598 | obsolete vesicular fraction(GO:0042598) |
0.0 | 0.7 | GO:0032589 | neuron projection membrane(GO:0032589) |
0.0 | 0.5 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
0.0 | 1.7 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
0.0 | 0.1 | GO:0005614 | interstitial matrix(GO:0005614) |
0.0 | 0.2 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
0.0 | 0.6 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
0.0 | 0.2 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
0.0 | 0.9 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
0.0 | 1.3 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
0.0 | 0.1 | GO:0016942 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) |
0.0 | 1.5 | GO:0030427 | site of polarized growth(GO:0030427) |
0.0 | 0.4 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.0 | 1.2 | GO:0005604 | basement membrane(GO:0005604) |
0.0 | 0.1 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.0 | 3.7 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
0.0 | 0.1 | GO:0000145 | exocyst(GO:0000145) |
0.0 | 1.1 | GO:0005938 | cell cortex(GO:0005938) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 3.9 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
0.6 | 1.7 | GO:0070052 | collagen V binding(GO:0070052) |
0.4 | 1.2 | GO:0005010 | insulin-like growth factor-activated receptor activity(GO:0005010) |
0.4 | 2.0 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
0.3 | 0.8 | GO:0004345 | glucose-6-phosphate dehydrogenase activity(GO:0004345) |
0.2 | 3.0 | GO:0005243 | gap junction channel activity(GO:0005243) |
0.2 | 0.6 | GO:0004768 | stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) |
0.2 | 0.6 | GO:0005137 | interleukin-5 receptor binding(GO:0005137) |
0.2 | 1.3 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
0.1 | 1.4 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
0.1 | 1.4 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.1 | 0.6 | GO:0009922 | fatty acid elongase activity(GO:0009922) |
0.1 | 1.2 | GO:0016857 | racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857) |
0.1 | 0.8 | GO:0031994 | insulin-like growth factor I binding(GO:0031994) |
0.1 | 0.9 | GO:0030172 | troponin C binding(GO:0030172) |
0.1 | 0.9 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
0.1 | 0.3 | GO:0004348 | glucosylceramidase activity(GO:0004348) |
0.1 | 0.2 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
0.1 | 0.5 | GO:0050693 | LBD domain binding(GO:0050693) |
0.1 | 0.3 | GO:0005046 | KDEL sequence binding(GO:0005046) |
0.1 | 0.2 | GO:0004802 | transketolase activity(GO:0004802) |
0.1 | 0.2 | GO:0004379 | glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107) |
0.1 | 0.2 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
0.1 | 1.5 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
0.1 | 0.2 | GO:0004731 | purine-nucleoside phosphorylase activity(GO:0004731) |
0.1 | 0.8 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.0 | 0.2 | GO:0031013 | troponin I binding(GO:0031013) |
0.0 | 0.8 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.0 | 0.8 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
0.0 | 0.2 | GO:0004597 | peptide-aspartate beta-dioxygenase activity(GO:0004597) |
0.0 | 0.2 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
0.0 | 1.0 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
0.0 | 0.2 | GO:0031708 | bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708) |
0.0 | 0.7 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
0.0 | 0.7 | GO:0004859 | phospholipase inhibitor activity(GO:0004859) |
0.0 | 0.2 | GO:0017147 | Wnt-protein binding(GO:0017147) |
0.0 | 0.7 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
0.0 | 0.5 | GO:0005313 | L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172) |
0.0 | 0.3 | GO:0016595 | glutamate binding(GO:0016595) |
0.0 | 0.8 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
0.0 | 0.8 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
0.0 | 0.5 | GO:0016780 | phosphotransferase activity, for other substituted phosphate groups(GO:0016780) |
0.0 | 0.4 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
0.0 | 1.8 | GO:0051287 | NAD binding(GO:0051287) |
0.0 | 0.6 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
0.0 | 0.5 | GO:0000146 | microfilament motor activity(GO:0000146) |
0.0 | 0.1 | GO:0019966 | interleukin-1 binding(GO:0019966) |
0.0 | 0.1 | GO:0034452 | dynactin binding(GO:0034452) |
0.0 | 0.5 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
0.0 | 0.3 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
0.0 | 0.6 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
0.0 | 0.4 | GO:0008186 | RNA-dependent ATPase activity(GO:0008186) |
0.0 | 0.2 | GO:0030332 | cyclin binding(GO:0030332) |
0.0 | 0.2 | GO:0004065 | arylsulfatase activity(GO:0004065) |
0.0 | 0.1 | GO:0005114 | type II transforming growth factor beta receptor binding(GO:0005114) |
0.0 | 0.4 | GO:0019003 | GDP binding(GO:0019003) |
0.0 | 0.6 | GO:0004177 | aminopeptidase activity(GO:0004177) |
0.0 | 0.6 | GO:0030165 | PDZ domain binding(GO:0030165) |
0.0 | 0.9 | GO:0004714 | transmembrane receptor protein tyrosine kinase activity(GO:0004714) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 3.8 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
0.1 | 3.7 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
0.0 | 0.8 | SA_G1_AND_S_PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
0.0 | 0.2 | ST_PAC1_RECEPTOR_PATHWAY | PAC1 Receptor Pathway |