Motif ID: GGAAUGU

Z-value: 1.380


Mature miRNA associated with seed GGAAUGU:

NamemiRBase Accession
hsa-miR-1-3p MIMAT0000416
hsa-miR-206 MIMAT0000462
hsa-miR-613 MIMAT0003281



Activity profile for motif GGAAUGU.

activity profile for motif GGAAUGU


Sorted Z-values histogram for motif GGAAUGU

Sorted Z-values for motif GGAAUGU



Network of associatons between targets according to the STRING database.



First level regulatory network of GGAAUGU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_41166953 3.889 ENST00000220772.3
SFRP1
secreted frizzled-related protein 1
chr6_+_121756809 2.984 ENST00000282561.3
GJA1
gap junction protein, alpha 1, 43kDa
chr3_-_123603137 1.979 ENST00000360304.3
ENST00000359169.1
ENST00000346322.5
ENST00000360772.3
MYLK



myosin light chain kinase



chr10_-_126849068 1.801 ENST00000494626.2
ENST00000337195.5
CTBP2

C-terminal binding protein 2

chr15_+_39873268 1.600 ENST00000397591.2
ENST00000260356.5
THBS1

thrombospondin 1

chr10_-_33623564 1.416 ENST00000374875.1
ENST00000374822.4
NRP1

neuropilin 1

chr8_-_49833978 1.394 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr13_-_107187462 1.388 ENST00000245323.4
EFNB2
ephrin-B2
chr6_+_116601265 1.302 ENST00000452085.3
DSE
dermatan sulfate epimerase
chr6_+_151561085 1.278 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr2_+_36582857 1.207 ENST00000280527.2
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr12_-_44200052 1.165 ENST00000548315.1
ENST00000552521.1
ENST00000546662.1
ENST00000548403.1
ENST00000546506.1
TWF1




twinfilin actin-binding protein 1




chr4_+_154125565 1.159 ENST00000338700.5
TRIM2
tripartite motif containing 2
chr3_-_134093395 1.130 ENST00000249883.5
AMOTL2
angiomotin like 2
chr3_-_149688896 1.115 ENST00000239940.7
PFN2
profilin 2
chr22_+_33197683 1.033 ENST00000266085.6
TIMP3
TIMP metallopeptidase inhibitor 3
chr9_-_110251836 0.984 ENST00000374672.4
KLF4
Kruppel-like factor 4 (gut)
chr1_+_25943959 0.935 ENST00000374332.4
MAN1C1
mannosidase, alpha, class 1C, member 1
chr1_-_95392635 0.927 ENST00000538964.1
ENST00000394202.4
ENST00000370206.4
CNN3


calponin 3, acidic


chr3_+_61547585 0.858 ENST00000295874.10
ENST00000474889.1
PTPRG

protein tyrosine phosphatase, receptor type, G

chr11_+_842808 0.827 ENST00000397397.2
ENST00000397411.2
ENST00000397396.1
TSPAN4


tetraspanin 4


chrX_-_153775426 0.821 ENST00000393562.2
G6PD
glucose-6-phosphate dehydrogenase
chr2_-_169104651 0.818 ENST00000355999.4
STK39
serine threonine kinase 39
chr2_-_217560248 0.753 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr2_+_202899310 0.737 ENST00000286201.1
FZD7
frizzled family receptor 7
chr17_+_38599693 0.733 ENST00000542955.1
ENST00000269593.4
IGFBP4

insulin-like growth factor binding protein 4

chr7_+_129932974 0.730 ENST00000445470.2
ENST00000222482.4
ENST00000492072.1
ENST00000473956.1
ENST00000493259.1
ENST00000486598.1
CPA4





carboxypeptidase A4





chr19_+_41725088 0.721 ENST00000301178.4
AXL
AXL receptor tyrosine kinase
chr1_-_171711387 0.699 ENST00000236192.7
VAMP4
vesicle-associated membrane protein 4
chr2_+_69969106 0.696 ENST00000409920.1
ENST00000394295.4
ENST00000536030.1
ANXA4


annexin A4


chr5_-_9546180 0.685 ENST00000382496.5
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr1_-_159893507 0.675 ENST00000368096.1
TAGLN2
transgelin 2
chr1_+_26606608 0.643 ENST00000319041.6
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr10_+_102106829 0.621 ENST00000370355.2
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr19_+_16187085 0.610 ENST00000300933.4
TPM4
tropomyosin 4
chr4_-_111119804 0.589 ENST00000394607.3
ENST00000302274.3
ELOVL6

ELOVL fatty acid elongase 6

chr12_+_72666407 0.583 ENST00000261180.4
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr17_+_68165657 0.581 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr7_-_87849340 0.572 ENST00000419179.1
ENST00000265729.2
SRI

sorcin

chr8_+_59465728 0.565 ENST00000260130.4
ENST00000422546.2
ENST00000447182.2
ENST00000413219.2
ENST00000424270.2
ENST00000523483.1
ENST00000520168.1
SDCBP






syndecan binding protein (syntenin)






chr15_+_42066632 0.549 ENST00000457542.2
ENST00000221214.6
ENST00000260357.7
ENST00000456763.2
MAPKBP1



mitogen-activated protein kinase binding protein 1



chr5_+_74632993 0.545 ENST00000287936.4
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
chr20_+_10199468 0.517 ENST00000254976.2
ENST00000304886.2
SNAP25

synaptosomal-associated protein, 25kDa

chr7_+_90225796 0.499 ENST00000380050.3
CDK14
cyclin-dependent kinase 14
chr15_+_65134088 0.487 ENST00000323544.4
ENST00000437723.1
PLEKHO2
AC069368.3
pleckstrin homology domain containing, family O member 2
Uncharacterized protein
chr11_+_69455855 0.486 ENST00000227507.2
ENST00000536559.1
CCND1

cyclin D1

chr15_-_59665062 0.484 ENST00000288235.4
MYO1E
myosin IE
chr11_-_796197 0.481 ENST00000530360.1
ENST00000528606.1
ENST00000320230.5
SLC25A22


solute carrier family 25 (mitochondrial carrier: glutamate), member 22


chr18_+_3451646 0.476 ENST00000345133.5
ENST00000330513.5
ENST00000549546.1
TGIF1


TGFB-induced factor homeobox 1


chr12_-_102224704 0.476 ENST00000299314.7
GNPTAB
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr6_-_139695757 0.468 ENST00000367651.2
CITED2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr5_+_151151471 0.449 ENST00000394123.3
ENST00000543466.1
G3BP1

GTPase activating protein (SH3 domain) binding protein 1

chr2_-_43453734 0.442 ENST00000282388.3
ZFP36L2
ZFP36 ring finger protein-like 2
chr8_-_116681221 0.441 ENST00000395715.3
TRPS1
trichorhinophalangeal syndrome I
chr15_-_60690163 0.425 ENST00000558998.1
ENST00000560165.1
ENST00000557986.1
ENST00000559780.1
ENST00000559467.1
ENST00000559956.1
ENST00000332680.4
ENST00000396024.3
ENST00000421017.2
ENST00000560466.1
ENST00000558132.1
ENST00000559113.1
ENST00000557906.1
ENST00000558558.1
ENST00000560468.1
ENST00000559370.1
ENST00000558169.1
ENST00000559725.1
ENST00000558985.1
ENST00000451270.2
ANXA2



















annexin A2



















chr12_-_46766577 0.421 ENST00000256689.5
SLC38A2
solute carrier family 38, member 2
chr1_+_84543734 0.418 ENST00000370689.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr4_-_10118469 0.413 ENST00000499869.2
WDR1
WD repeat domain 1
chr19_-_4400415 0.404 ENST00000598564.1
ENST00000417295.2
ENST00000269886.3
SH3GL1


SH3-domain GRB2-like 1


chr12_+_12764773 0.395 ENST00000228865.2
CREBL2
cAMP responsive element binding protein-like 2
chr1_-_39325431 0.391 ENST00000373001.3
RRAGC
Ras-related GTP binding C
chr20_-_35374456 0.385 ENST00000373803.2
ENST00000359675.2
ENST00000540765.1
ENST00000349004.1
NDRG3



NDRG family member 3



chrX_+_12993202 0.354 ENST00000451311.2
ENST00000380636.1
TMSB4X

thymosin beta 4, X-linked

chr2_+_201170703 0.350 ENST00000358677.5
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr1_+_19923454 0.345 ENST00000322753.6
ENST00000602662.1
ENST00000602293.1
MINOS1
MINOS1-NBL1

mitochondrial inner membrane organizing system 1
MINOS1-NBL1 readthrough

chr4_-_2264015 0.344 ENST00000337190.2
MXD4
MAX dimerization protein 4
chr2_-_39664405 0.337 ENST00000341681.5
ENST00000263881.3
MAP4K3

mitogen-activated protein kinase kinase kinase kinase 3

chr1_-_155211017 0.331 ENST00000536770.1
ENST00000368373.3
GBA

glucosidase, beta, acid

chr1_+_160175117 0.325 ENST00000360472.4
PEA15
phosphoprotein enriched in astrocytes 15
chr14_-_20020272 0.323 ENST00000551509.1
POTEM
POTE ankyrin domain family, member M
chrX_+_110339439 0.322 ENST00000372010.1
ENST00000519681.1
ENST00000372007.5
PAK3


p21 protein (Cdc42/Rac)-activated kinase 3


chr3_-_57583130 0.315 ENST00000303436.6
ARF4
ADP-ribosylation factor 4
chr12_+_79258547 0.314 ENST00000457153.2
SYT1
synaptotagmin I
chr12_-_49351303 0.313 ENST00000256682.4
ARF3
ADP-ribosylation factor 3
chr7_-_6523755 0.312 ENST00000258739.4
ENST00000436575.1
KDELR2
DAGLB
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
diacylglycerol lipase, beta
chr12_+_72233487 0.311 ENST00000482439.2
ENST00000550746.1
ENST00000491063.1
ENST00000319106.8
ENST00000485960.2
ENST00000393309.3
TBC1D15





TBC1 domain family, member 15





chr17_-_41174424 0.310 ENST00000355653.3
VAT1
vesicle amine transport 1
chr13_-_108518986 0.309 ENST00000375915.2
FAM155A
family with sequence similarity 155, member A
chr6_+_149068464 0.307 ENST00000367463.4
UST
uronyl-2-sulfotransferase
chr6_-_53409890 0.295 ENST00000229416.6
GCLC
glutamate-cysteine ligase, catalytic subunit
chr7_-_15726296 0.294 ENST00000262041.5
MEOX2
mesenchyme homeobox 2
chr2_-_47403642 0.294 ENST00000456319.1
ENST00000409563.1
ENST00000272298.7
CALM2


calmodulin 2 (phosphorylase kinase, delta)


chr4_+_41992489 0.287 ENST00000264451.7
SLC30A9
solute carrier family 30 (zinc transporter), member 9
chr3_+_132136331 0.283 ENST00000260818.6
DNAJC13
DnaJ (Hsp40) homolog, subfamily C, member 13
chr7_-_79082867 0.278 ENST00000419488.1
ENST00000354212.4
MAGI2

membrane associated guanylate kinase, WW and PDZ domain containing 2

chr7_+_98923505 0.277 ENST00000432884.2
ENST00000262942.5
ARPC1A

actin related protein 2/3 complex, subunit 1A, 41kDa

chr4_-_22517620 0.274 ENST00000502482.1
ENST00000334304.5
GPR125

G protein-coupled receptor 125

chr14_+_19553365 0.274 ENST00000409832.3
POTEG
POTE ankyrin domain family, member G
chr12_-_118797475 0.272 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAOK3


TAO kinase 3


chr20_-_17662878 0.272 ENST00000377813.1
ENST00000377807.2
ENST00000360807.4
ENST00000398782.2
RRBP1



ribosome binding protein 1



chr7_-_129592700 0.268 ENST00000472396.1
ENST00000355621.3
UBE2H

ubiquitin-conjugating enzyme E2H

chr11_+_86748863 0.268 ENST00000340353.7
TMEM135
transmembrane protein 135
chr7_+_100797678 0.264 ENST00000337619.5
AP1S1
adaptor-related protein complex 1, sigma 1 subunit
chr15_-_48470558 0.259 ENST00000324324.7
MYEF2
myelin expression factor 2
chr6_+_114178512 0.253 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr3_+_127771212 0.251 ENST00000243253.3
ENST00000481210.1
SEC61A1

Sec61 alpha 1 subunit (S. cerevisiae)

chr1_+_24829384 0.250 ENST00000374395.4
ENST00000436717.2
RCAN3

RCAN family member 3

chrX_+_80457442 0.249 ENST00000373212.5
SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr1_+_18958008 0.245 ENST00000420770.2
ENST00000400661.3
PAX7

paired box 7

chr5_+_176560742 0.244 ENST00000439151.2
NSD1
nuclear receptor binding SET domain protein 1
chr15_-_101792137 0.244 ENST00000254190.3
CHSY1
chondroitin sulfate synthase 1
chr2_+_70142189 0.233 ENST00000264444.2
MXD1
MAX dimerization protein 1
chr12_-_120907459 0.229 ENST00000229390.3
SRSF9
serine/arginine-rich splicing factor 9
chr1_-_175161890 0.227 ENST00000545251.2
ENST00000423313.1
KIAA0040

KIAA0040

chr12_-_76953284 0.225 ENST00000547544.1
ENST00000393249.2
OSBPL8

oxysterol binding protein-like 8

chr7_-_123389104 0.219 ENST00000223023.4
WASL
Wiskott-Aldrich syndrome-like
chr1_+_167691191 0.216 ENST00000392121.3
ENST00000474859.1
MPZL1

myelin protein zero-like 1

chr17_-_73851285 0.214 ENST00000589642.1
ENST00000593002.1
ENST00000590221.1
ENST00000344296.4
ENST00000587374.1
ENST00000585462.1
ENST00000433525.2
ENST00000254806.3
WBP2







WW domain binding protein 2







chr18_+_42260861 0.214 ENST00000282030.5
SETBP1
SET binding protein 1
chr3_-_53290016 0.212 ENST00000423525.2
ENST00000423516.1
ENST00000296289.6
ENST00000462138.1
TKT



transketolase



chr19_+_45973120 0.211 ENST00000592811.1
ENST00000586615.1
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr1_+_155179012 0.210 ENST00000609421.1
MTX1
metaxin 1
chr8_-_101965146 0.210 ENST00000395957.2
ENST00000395948.2
ENST00000457309.1
YWHAZ


tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta


chr19_+_56152262 0.207 ENST00000325333.5
ENST00000590190.1
ZNF580

zinc finger protein 580

chr14_-_92506371 0.205 ENST00000267622.4
TRIP11
thyroid hormone receptor interactor 11
chr4_-_926069 0.203 ENST00000314167.4
ENST00000502656.1
GAK

cyclin G associated kinase

chrX_-_48901012 0.202 ENST00000315869.7
TFE3
transcription factor binding to IGHM enhancer 3
chr17_+_38375574 0.202 ENST00000323571.4
ENST00000585043.1
ENST00000394103.3
ENST00000536600.1
WIPF2



WAS/WASL interacting protein family, member 2



chr11_-_27528301 0.201 ENST00000524596.1
ENST00000278193.2
LIN7C

lin-7 homolog C (C. elegans)

chr2_-_131267239 0.200 ENST00000451531.2
POTEI
POTE ankyrin domain family, member I
chr10_-_15210666 0.199 ENST00000378165.4
NMT2
N-myristoyltransferase 2
chr1_+_64239657 0.197 ENST00000371080.1
ENST00000371079.1
ROR1

receptor tyrosine kinase-like orphan receptor 1

chr11_-_76091986 0.196 ENST00000260045.3
PRKRIR
protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
chr6_+_12290586 0.196 ENST00000379375.5
EDN1
endothelin 1
chr21_+_39628655 0.188 ENST00000398925.1
ENST00000398928.1
ENST00000328656.4
ENST00000443341.1
KCNJ15



potassium inwardly-rectifying channel, subfamily J, member 15



chr14_+_23775971 0.187 ENST00000250405.5
BCL2L2
BCL2-like 2
chr9_-_80646374 0.187 ENST00000286548.4
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr8_+_70378852 0.186 ENST00000525061.1
ENST00000458141.2
ENST00000260128.4
SULF1


sulfatase 1


chr2_-_9563319 0.185 ENST00000497105.1
ENST00000360635.3
ENST00000359712.3
ITGB1BP1


integrin beta 1 binding protein 1


chr10_+_76586348 0.184 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
KAT6B


K(lysine) acetyltransferase 6B


chr1_-_200379180 0.182 ENST00000294740.3
ZNF281
zinc finger protein 281
chr9_-_107690420 0.179 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
ABCA1


ATP-binding cassette, sub-family A (ABC1), member 1


chr13_-_36050819 0.177 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr7_+_116312411 0.176 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
MET


met proto-oncogene


chr2_-_9770706 0.176 ENST00000381844.4
YWHAQ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
chr4_+_153701081 0.174 ENST00000451320.2
ENST00000429148.2
ENST00000353617.2
ENST00000405727.2
ENST00000356064.3
ARFIP1




ADP-ribosylation factor interacting protein 1




chr19_-_5622991 0.173 ENST00000252542.4
SAFB2
scaffold attachment factor B2
chr17_-_43568062 0.171 ENST00000421073.2
ENST00000584420.1
ENST00000589780.1
ENST00000430334.3
PLEKHM1



pleckstrin homology domain containing, family M (with RUN domain) member 1



chr8_-_62627057 0.168 ENST00000519234.1
ENST00000379449.6
ENST00000379454.4
ENST00000518068.1
ENST00000517856.1
ENST00000356457.5
ASPH





aspartate beta-hydroxylase





chr2_+_99225018 0.167 ENST00000357765.2
ENST00000409975.1
UNC50

unc-50 homolog (C. elegans)

chr14_+_20937538 0.165 ENST00000361505.5
ENST00000553591.1
PNP

purine nucleoside phosphorylase

chr15_+_43803143 0.162 ENST00000382031.1
MAP1A
microtubule-associated protein 1A
chrX_-_112084043 0.162 ENST00000304758.1
AMOT
angiomotin
chr2_+_134877740 0.157 ENST00000409645.1
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr17_+_45973516 0.156 ENST00000376741.4
SP2
Sp2 transcription factor
chr20_+_43104508 0.154 ENST00000262605.4
ENST00000372904.3
TTPAL

tocopherol (alpha) transfer protein-like

chr14_+_102829300 0.151 ENST00000359520.7
TECPR2
tectonin beta-propeller repeat containing 2
chr7_+_77325738 0.151 ENST00000334955.8
RSBN1L
round spermatid basic protein 1-like
chr22_-_38902325 0.150 ENST00000396821.3
ENST00000381633.3
DDX17

DEAD (Asp-Glu-Ala-Asp) box helicase 17

chr1_-_180991978 0.150 ENST00000542060.1
ENST00000258301.5
STX6

syntaxin 6

chr17_+_57784826 0.149 ENST00000262291.4
VMP1
vacuole membrane protein 1
chr14_+_69865401 0.149 ENST00000556605.1
ENST00000336643.5
ENST00000031146.4
SLC39A9


solute carrier family 39, member 9


chr1_+_28099683 0.148 ENST00000373943.4
STX12
syntaxin 12
chr20_-_36156125 0.145 ENST00000397135.1
ENST00000397137.1
BLCAP

bladder cancer associated protein

chr13_+_49550015 0.145 ENST00000492622.2
FNDC3A
fibronectin type III domain containing 3A
chr15_-_64455404 0.143 ENST00000300026.3
PPIB
peptidylprolyl isomerase B (cyclophilin B)
chr14_-_55878538 0.141 ENST00000247178.5
ATG14
autophagy related 14
chr17_+_70117153 0.139 ENST00000245479.2
SOX9
SRY (sex determining region Y)-box 9
chrX_+_28605516 0.138 ENST00000378993.1
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr15_+_59063478 0.136 ENST00000559228.1
ENST00000450403.2
FAM63B

family with sequence similarity 63, member B

chr12_+_121148228 0.134 ENST00000344651.4
UNC119B
unc-119 homolog B (C. elegans)
chr16_+_84853580 0.132 ENST00000262424.5
ENST00000566151.1
ENST00000567845.1
ENST00000564567.1
ENST00000569090.1
CRISPLD2




cysteine-rich secretory protein LCCL domain containing 2




chr3_+_113465866 0.130 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATP6V1A



ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A



chr9_+_35749203 0.130 ENST00000456972.2
ENST00000378078.4
RGP1

RGP1 retrograde golgi transport homolog (S. cerevisiae)

chr7_-_93633684 0.127 ENST00000222547.3
ENST00000425626.1
BET1

Bet1 golgi vesicular membrane trafficking protein

chr1_-_92351769 0.126 ENST00000212355.4
TGFBR3
transforming growth factor, beta receptor III
chr2_+_220042933 0.118 ENST00000430297.2
FAM134A
family with sequence similarity 134, member A
chr19_-_2151523 0.117 ENST00000350812.6
ENST00000355272.6
ENST00000356926.4
ENST00000345016.5
AP3D1



adaptor-related protein complex 3, delta 1 subunit



chr16_+_30960375 0.115 ENST00000318663.4
ENST00000566237.1
ENST00000562699.1
ORAI3


ORAI calcium release-activated calcium modulator 3


chr5_-_94620239 0.112 ENST00000515393.1
MCTP1
multiple C2 domains, transmembrane 1
chr14_+_90863327 0.112 ENST00000356978.4
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr9_-_95298314 0.112 ENST00000344604.5
ENST00000375540.1
ECM2

extracellular matrix protein 2, female organ and adipocyte specific

chr7_-_5570229 0.108 ENST00000331789.5
ACTB
actin, beta
chr10_+_180987 0.106 ENST00000381591.1
ZMYND11
zinc finger, MYND-type containing 11
chr2_+_178077477 0.104 ENST00000411529.2
ENST00000435711.1
HNRNPA3

heterogeneous nuclear ribonucleoprotein A3

chr22_-_39268308 0.104 ENST00000407418.3
CBX6
chromobox homolog 6
chr16_-_30134524 0.104 ENST00000395202.1
ENST00000395199.3
ENST00000263025.4
ENST00000322266.5
ENST00000403394.1
MAPK3




mitogen-activated protein kinase 3




chr20_+_18488137 0.103 ENST00000450074.1
ENST00000262544.2
ENST00000336714.3
ENST00000377475.3
SEC23B



Sec23 homolog B (S. cerevisiae)



chr5_+_175792459 0.102 ENST00000310389.5
ARL10
ADP-ribosylation factor-like 10
chr2_+_242255275 0.101 ENST00000391971.2
SEPT2
septin 2
chr18_-_61034743 0.099 ENST00000406396.3
KDSR
3-ketodihydrosphingosine reductase
chr8_+_20054878 0.099 ENST00000276390.2
ENST00000519667.1
ATP6V1B2

ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2

chr15_-_73076030 0.097 ENST00000311669.8
ADPGK
ADP-dependent glucokinase
chr17_+_2496971 0.097 ENST00000397195.5
PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr17_-_2304365 0.096 ENST00000575394.1
ENST00000174618.4
MNT

MAX network transcriptional repressor

chr2_-_26101374 0.095 ENST00000435504.4
ASXL2
additional sex combs like 2 (Drosophila)
chr12_-_22697343 0.094 ENST00000446597.1
ENST00000536386.1
ENST00000396028.2
ENST00000545552.1
ENST00000544930.1
ENST00000333957.4
C2CD5





C2 calcium-dependent domain containing 5





chr9_+_115983808 0.094 ENST00000374210.6
ENST00000374212.4
SLC31A1

solute carrier family 31 (copper transporter), member 1

chr11_+_118230287 0.093 ENST00000252108.3
ENST00000431736.2
UBE4A

ubiquitination factor E4A

chr9_+_77703414 0.093 ENST00000346234.6
OSTF1
osteoclast stimulating factor 1
chr15_+_31619013 0.092 ENST00000307145.3
KLF13
Kruppel-like factor 13
chr10_+_93558069 0.092 ENST00000371627.4
TNKS2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr14_-_99737565 0.092 ENST00000357195.3
BCL11B
B-cell CLL/lymphoma 11B (zinc finger protein)
chr3_+_169940153 0.090 ENST00000295797.4
PRKCI
protein kinase C, iota
chr13_+_58206655 0.087 ENST00000377918.3
PCDH17
protocadherin 17
chr4_+_170541660 0.086 ENST00000513761.1
ENST00000347613.4
CLCN3

chloride channel, voltage-sensitive 3

chr12_-_31945172 0.081 ENST00000340398.3
H3F3C
H3 histone, family 3C
chr3_-_186080012 0.080 ENST00000544847.1
ENST00000265022.3
DGKG

diacylglycerol kinase, gamma 90kDa

chr11_-_86666427 0.080 ENST00000531380.1
FZD4
frizzled family receptor 4
chr17_-_62502639 0.077 ENST00000225792.5
ENST00000581697.1
ENST00000584279.1
ENST00000577922.1
DDX5



DEAD (Asp-Glu-Ala-Asp) box helicase 5




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0014029 neural crest formation(GO:0014029) neural crest cell fate commitment(GO:0014034) convergent extension involved in axis elongation(GO:0060028) cellular response to prostaglandin E stimulus(GO:0071380) response to heparin(GO:0071503) cellular response to heparin(GO:0071504) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.7 3.0 GO:0051503 purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503)
0.5 1.6 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.4 1.3 GO:0030205 dermatan sulfate metabolic process(GO:0030205) dermatan sulfate biosynthetic process(GO:0030208)
0.3 2.0 GO:0060414 aorta development(GO:0035904) aorta morphogenesis(GO:0035909) aorta smooth muscle tissue morphogenesis(GO:0060414)
0.3 0.8 GO:0006740 NADPH regeneration(GO:0006740)
0.2 0.7 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.2 1.4 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.2 1.0 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.2 0.6 GO:0042759 fatty acid elongation, saturated fatty acid(GO:0019367) long-chain fatty acid biosynthetic process(GO:0042759)
0.2 0.2 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.2 0.5 GO:0016081 synaptic vesicle docking(GO:0016081) calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2 1.0 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.2 1.4 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 1.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 1.8 GO:0050872 white fat cell differentiation(GO:0050872)
0.1 0.8 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.1 1.4 GO:0001945 lymph vessel development(GO:0001945)
0.1 0.8 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.4 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.3 GO:0001757 somite specification(GO:0001757)
0.1 0.4 GO:0033197 response to vitamin E(GO:0033197)
0.1 0.6 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 0.2 GO:0034770 histone H4-K20 methylation(GO:0034770)
0.1 0.3 GO:0051409 response to nitrosative stress(GO:0051409)
0.1 0.2 GO:0005997 xylulose metabolic process(GO:0005997)
0.1 0.5 GO:0008354 germ cell migration(GO:0008354)
0.1 0.2 GO:0018377 N-terminal protein myristoylation(GO:0006499) protein myristoylation(GO:0018377)
0.1 0.4 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.2 GO:0046102 nicotinamide riboside catabolic process(GO:0006738) inosine metabolic process(GO:0046102) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.1 0.3 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.1 0.5 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.1 0.4 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.2 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.1 GO:0007538 primary sex determination(GO:0007538)
0.0 0.3 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0060318 definitive erythrocyte differentiation(GO:0060318)
0.0 0.3 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.2 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.1 GO:0032119 sequestering of zinc ion(GO:0032119) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.2 GO:0034204 Cdc42 protein signal transduction(GO:0032488) lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.5 GO:0034405 response to fluid shear stress(GO:0034405)
0.0 0.1 GO:1904358 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.1 GO:0061298 progesterone secretion(GO:0042701) retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0046469 layer formation in cerebral cortex(GO:0021819) platelet activating factor metabolic process(GO:0046469)
0.0 0.0 GO:0097576 autophagosome maturation(GO:0097352) vacuole fusion(GO:0097576)
0.0 0.2 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 0.3 GO:0043113 receptor clustering(GO:0043113)
0.0 0.3 GO:0045047 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0 0.6 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.2 GO:0060158 neuron remodeling(GO:0016322) regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932) phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.1 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.1 GO:0051927 obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.5 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.1 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.4 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.0 GO:0010996 mechanosensory behavior(GO:0007638) response to auditory stimulus(GO:0010996) operant conditioning(GO:0035106)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.4 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 1.3 GO:0008064 regulation of actin polymerization or depolymerization(GO:0008064)
0.0 0.3 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.0 GO:0010544 regulation of phosphatidylinositol biosynthetic process(GO:0010511) negative regulation of platelet activation(GO:0010544) regulation of phospholipid biosynthetic process(GO:0071071)
0.0 0.1 GO:0006906 vesicle fusion(GO:0006906)
0.0 0.1 GO:0061339 establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.9 GO:0006939 smooth muscle contraction(GO:0006939)
0.0 0.2 GO:0030201 heparan sulfate proteoglycan metabolic process(GO:0030201)
0.0 0.1 GO:0046519 sphingoid metabolic process(GO:0046519)
0.0 0.0 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.7 GO:0031668 cellular response to extracellular stimulus(GO:0031668)
0.0 0.3 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.0 GO:0005916 fascia adherens(GO:0005916)
0.2 0.5 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.2 0.5 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 1.6 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.3 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.3 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.2 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 0.7 GO:0032589 neuron projection membrane(GO:0032589)
0.0 0.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 1.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.3 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.1 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 1.5 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 1.2 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 3.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0000145 exocyst(GO:0000145)
0.0 1.1 GO:0005938 cell cortex(GO:0005938)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.9 GO:0061133 endopeptidase activator activity(GO:0061133)
0.6 1.7 GO:0070052 collagen V binding(GO:0070052)
0.4 1.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.4 2.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.3 0.8 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.2 3.0 GO:0005243 gap junction channel activity(GO:0005243)
0.2 0.6 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.2 0.6 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.2 1.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 1.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.6 GO:0009922 fatty acid elongase activity(GO:0009922)
0.1 1.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 0.8 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.1 0.9 GO:0030172 troponin C binding(GO:0030172)
0.1 0.9 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.3 GO:0004348 glucosylceramidase activity(GO:0004348)
0.1 0.2 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.5 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.3 GO:0005046 KDEL sequence binding(GO:0005046)
0.1 0.2 GO:0004802 transketolase activity(GO:0004802)
0.1 0.2 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.1 0.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 1.5 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.2 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 1.0 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.2 GO:0031708 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.7 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.2 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.5 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0 0.3 GO:0016595 glutamate binding(GO:0016595)
0.0 0.8 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.8 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.5 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 1.8 GO:0051287 NAD binding(GO:0051287)
0.0 0.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.5 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.6 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.4 GO:0008186 RNA-dependent ATPase activity(GO:0008186)
0.0 0.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.4 GO:0019003 GDP binding(GO:0019003)
0.0 0.6 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.6 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.9 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.8 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.1 3.7 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.8 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.2 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway