Motif ID: GGAGUGU

Z-value: 0.344


Mature miRNA associated with seed GGAGUGU:

NamemiRBase Accession
hsa-miR-122-5p MIMAT0000421



Activity profile for motif GGAGUGU.

activity profile for motif GGAGUGU


Sorted Z-values histogram for motif GGAGUGU

Sorted Z-values for motif GGAGUGU



Network of associatons between targets according to the STRING database.



First level regulatory network of GGAGUGU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_72748417 0.271 ENST00000357731.5
 NEGR1
neuronal growth regulator 1
chr2_-_96811170 0.231 ENST00000288943.4
 DUSP2
dual specificity phosphatase 2
chr16_+_69599861 0.216 ENST00000354436.2
 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr7_+_94285637 0.213 ENST00000482108.1
ENST00000488574.1
 PEG10

paternally expressed 10

chr10_-_74856608 0.151 ENST00000307116.2
ENST00000373008.2
ENST00000412021.2
ENST00000394890.2
ENST00000263556.3
ENST00000440381.1
 P4HA1





prolyl 4-hydroxylase, alpha polypeptide I





chr16_+_30077055 0.138 ENST00000564595.2
ENST00000569798.1
 ALDOA

aldolase A, fructose-bisphosphate

chr10_+_70480963 0.120 ENST00000265872.6
ENST00000535016.1
ENST00000538031.1
ENST00000543719.1
ENST00000539539.1
ENST00000543225.1
ENST00000536012.1
ENST00000494903.2
 CCAR1







cell division cycle and apoptosis regulator 1







chr15_-_34628951 0.114 ENST00000397707.2
ENST00000560611.1
 SLC12A6

solute carrier family 12 (potassium/chloride transporter), member 6

chr1_-_245027833 0.102 ENST00000444376.2
 HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr10_-_23003460 0.096 ENST00000376573.4
 PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr8_-_29208183 0.096 ENST00000240100.2
 DUSP4
dual specificity phosphatase 4
chr8_-_57123815 0.089 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
 PLAG1


pleiomorphic adenoma gene 1


chr4_-_103266219 0.083 ENST00000394833.2
 SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr6_+_72596604 0.067 ENST00000348717.5
ENST00000517960.1
ENST00000518273.1
ENST00000522291.1
ENST00000521978.1
ENST00000520567.1
ENST00000264839.7
 RIMS1






regulating synaptic membrane exocytosis 1






chr17_-_27916621 0.064 ENST00000225394.3
 GIT1
G protein-coupled receptor kinase interacting ArfGAP 1
chr6_+_108881012 0.063 ENST00000343882.6
 FOXO3
forkhead box O3
chr19_-_47291843 0.057 ENST00000542575.2
 SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr11_+_119076745 0.055 ENST00000264033.4
 CBL
Cbl proto-oncogene, E3 ubiquitin protein ligase
chr5_+_162864575 0.055 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
 CCNG1






cyclin G1






chr5_+_96271141 0.049 ENST00000231368.5
 LNPEP
leucyl/cystinyl aminopeptidase
chr15_-_72523454 0.047 ENST00000565154.1
ENST00000565184.1
ENST00000389093.3
ENST00000449901.2
ENST00000335181.5
ENST00000319622.6
 PKM





pyruvate kinase, muscle





chr17_+_41857793 0.046 ENST00000449302.3
 C17orf105
chromosome 17 open reading frame 105
chr7_-_95225768 0.044 ENST00000005178.5
 PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr8_+_102504651 0.042 ENST00000251808.3
ENST00000521085.1
 GRHL2

grainyhead-like 2 (Drosophila)

chr1_+_36348790 0.036 ENST00000373204.4
 AGO1
argonaute RISC catalytic component 1
chr6_+_152011628 0.034 ENST00000404742.1
ENST00000440973.1
 ESR1

estrogen receptor 1

chr1_+_27114418 0.033 ENST00000078527.4
 PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr19_-_2456922 0.032 ENST00000582871.1
ENST00000325327.3
 LMNB2

lamin B2

chr20_+_32581452 0.029 ENST00000375114.3
ENST00000448364.1
 RALY

RALY heterogeneous nuclear ribonucleoprotein

chr6_-_45983581 0.028 ENST00000339561.6
 CLIC5
chloride intracellular channel 5
chr7_+_100318423 0.023 ENST00000252723.2
 EPO
erythropoietin
chr14_+_33408449 0.022 ENST00000346562.2
ENST00000341321.4
ENST00000548645.1
ENST00000356141.4
ENST00000357798.5
 NPAS3




neuronal PAS domain protein 3




chr19_-_8373173 0.020 ENST00000537716.2
ENST00000301458.5
 CD320

CD320 molecule

chr6_-_35464727 0.020 ENST00000402886.3
 TEAD3
TEA domain family member 3
chr22_+_38201114 0.019 ENST00000340857.2
 H1F0
H1 histone family, member 0
chr21_-_40685477 0.017 ENST00000342449.3
 BRWD1
bromodomain and WD repeat domain containing 1
chr11_-_108369101 0.017 ENST00000323468.5
 KDELC2
KDEL (Lys-Asp-Glu-Leu) containing 2
chr8_-_117886955 0.013 ENST00000297338.2
 RAD21
RAD21 homolog (S. pombe)
chr19_-_6279932 0.010 ENST00000252674.7
 MLLT1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr1_-_109940550 0.007 ENST00000256637.6
 SORT1
sortilin 1
chr5_-_11904152 0.005 ENST00000304623.8
ENST00000458100.2
 CTNND2

catenin (cadherin-associated protein), delta 2

chr2_-_219925189 0.005 ENST00000295731.6
 IHH
indian hedgehog
chr17_-_4269768 0.003 ENST00000396981.2
 UBE2G1
ubiquitin-conjugating enzyme E2G 1
chr16_-_30381580 0.003 ENST00000409939.3
 TBC1D10B
TBC1 domain family, member 10B
chr14_-_77787198 0.002 ENST00000261534.4
 POMT2
protein-O-mannosyltransferase 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.3 GO:0001706 endoderm formation(GO:0001706)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 0.1 GO:1903561 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.0 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)