Motif ID: GLI2
Z-value: 1.621
Transcription factors associated with GLI2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| GLI2 | ENSG00000074047.16 | GLI2 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 5.7 | GO:0010900 | regulation of phosphatidylcholine catabolic process(GO:0010899) negative regulation of phosphatidylcholine catabolic process(GO:0010900) |
| 0.4 | 1.3 | GO:0015920 | lipopolysaccharide transport(GO:0015920) |
| 0.4 | 1.6 | GO:0018352 | protein-pyridoxal-5-phosphate linkage(GO:0018352) |
| 0.4 | 1.2 | GO:0051066 | dihydrobiopterin metabolic process(GO:0051066) |
| 0.4 | 1.1 | GO:1904036 | negative regulation of epithelial cell apoptotic process(GO:1904036) negative regulation of endothelial cell apoptotic process(GO:2000352) |
| 0.3 | 1.3 | GO:1904035 | endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) positive regulation of epithelial cell apoptotic process(GO:1904037) regulation of endothelial cell apoptotic process(GO:2000351) positive regulation of endothelial cell apoptotic process(GO:2000353) |
| 0.3 | 1.3 | GO:0046671 | regulation of nitrogen utilization(GO:0006808) positive regulation of neuron maturation(GO:0014042) nitrogen utilization(GO:0019740) cochlear nucleus development(GO:0021747) negative regulation of cellular pH reduction(GO:0032848) glial cell apoptotic process(GO:0034349) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671) positive regulation of cell maturation(GO:1903431) |
| 0.3 | 1.8 | GO:0009450 | gamma-aminobutyric acid catabolic process(GO:0009450) |
| 0.3 | 1.9 | GO:0071267 | amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267) |
| 0.3 | 0.8 | GO:0034625 | fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.3 | 1.3 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 0.3 | 0.8 | GO:0005997 | xylulose metabolic process(GO:0005997) |
| 0.2 | 1.6 | GO:0015755 | fructose transport(GO:0015755) |
| 0.2 | 1.6 | GO:0045423 | regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425) |
| 0.2 | 1.1 | GO:0034204 | lipid translocation(GO:0034204) phospholipid translocation(GO:0045332) |
| 0.2 | 0.8 | GO:0010157 | response to chlorate(GO:0010157) |
| 0.2 | 0.6 | GO:0032328 | alanine transport(GO:0032328) |
| 0.2 | 0.8 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.2 | 0.9 | GO:0006549 | isoleucine metabolic process(GO:0006549) |
| 0.2 | 0.9 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.2 | 1.1 | GO:0030174 | regulation of DNA-dependent DNA replication initiation(GO:0030174) |
| 0.2 | 0.8 | GO:0031665 | negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665) |
| 0.2 | 0.5 | GO:0060316 | positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) |
| 0.1 | 0.6 | GO:0060025 | regulation of synaptic activity(GO:0060025) |
| 0.1 | 1.2 | GO:0006516 | glycoprotein catabolic process(GO:0006516) |
| 0.1 | 0.4 | GO:0043461 | proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272) |
| 0.1 | 0.4 | GO:0071848 | regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) TNFSF11-mediated signaling pathway(GO:0071847) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009) |
| 0.1 | 0.4 | GO:0001552 | ovarian follicle atresia(GO:0001552) |
| 0.1 | 2.1 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
| 0.1 | 0.4 | GO:0036037 | CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 0.1 | 0.3 | GO:0002291 | T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291) |
| 0.1 | 0.4 | GO:0021631 | optic nerve morphogenesis(GO:0021631) |
| 0.1 | 0.7 | GO:0006999 | nuclear pore organization(GO:0006999) |
| 0.1 | 1.9 | GO:0006386 | transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386) |
| 0.1 | 0.3 | GO:0010586 | miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587) |
| 0.1 | 0.3 | GO:0051083 | 'de novo' cotranslational protein folding(GO:0051083) |
| 0.1 | 0.9 | GO:0051096 | meiotic mismatch repair(GO:0000710) positive regulation of helicase activity(GO:0051096) |
| 0.1 | 0.5 | GO:0051147 | regulation of muscle cell differentiation(GO:0051147) positive regulation of muscle cell differentiation(GO:0051149) |
| 0.1 | 0.6 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.1 | 0.4 | GO:0045085 | negative regulation of interleukin-2 biosynthetic process(GO:0045085) |
| 0.1 | 0.7 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
| 0.1 | 0.3 | GO:0006478 | peptidyl-tyrosine sulfation(GO:0006478) |
| 0.1 | 0.4 | GO:0051582 | auditory behavior(GO:0031223) positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) |
| 0.1 | 0.3 | GO:0033590 | response to cobalamin(GO:0033590) |
| 0.1 | 0.9 | GO:0043248 | proteasome assembly(GO:0043248) |
| 0.1 | 0.4 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470) |
| 0.1 | 0.2 | GO:0045908 | negative regulation of vasodilation(GO:0045908) |
| 0.1 | 1.3 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 0.1 | 1.3 | GO:0030252 | growth hormone secretion(GO:0030252) |
| 0.1 | 0.3 | GO:0045199 | maintenance of epithelial cell apical/basal polarity(GO:0045199) |
| 0.1 | 0.3 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.1 | 2.5 | GO:0060334 | regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334) |
| 0.1 | 0.7 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.1 | 0.9 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 0.1 | 0.9 | GO:0055069 | cellular zinc ion homeostasis(GO:0006882) zinc ion homeostasis(GO:0055069) |
| 0.1 | 4.4 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.1 | 0.8 | GO:0045824 | negative regulation of innate immune response(GO:0045824) |
| 0.1 | 0.2 | GO:0071679 | facial nucleus development(GO:0021754) cell proliferation in midbrain(GO:0033278) commissural neuron axon guidance(GO:0071679) |
| 0.1 | 1.2 | GO:0050930 | induction of positive chemotaxis(GO:0050930) |
| 0.1 | 0.1 | GO:0060535 | trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536) |
| 0.1 | 0.3 | GO:0010944 | negative regulation of transcription by competitive promoter binding(GO:0010944) |
| 0.1 | 1.4 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 0.1 | 2.7 | GO:0002286 | T cell activation involved in immune response(GO:0002286) |
| 0.1 | 0.8 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
| 0.1 | 0.2 | GO:0006419 | alanyl-tRNA aminoacylation(GO:0006419) |
| 0.1 | 0.7 | GO:0018216 | peptidyl-arginine methylation(GO:0018216) |
| 0.1 | 1.2 | GO:0090399 | replicative senescence(GO:0090399) |
| 0.1 | 0.2 | GO:0006428 | isoleucyl-tRNA aminoacylation(GO:0006428) |
| 0.1 | 0.7 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.1 | 0.2 | GO:0000466 | maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466) |
| 0.1 | 0.5 | GO:0051051 | negative regulation of transport(GO:0051051) |
| 0.1 | 0.3 | GO:0030578 | nuclear body organization(GO:0030575) PML body organization(GO:0030578) |
| 0.1 | 0.4 | GO:0010815 | bradykinin catabolic process(GO:0010815) |
| 0.1 | 0.3 | GO:0070849 | response to epidermal growth factor(GO:0070849) |
| 0.1 | 1.5 | GO:0030593 | neutrophil chemotaxis(GO:0030593) neutrophil migration(GO:1990266) |
| 0.1 | 1.2 | GO:0045668 | negative regulation of osteoblast differentiation(GO:0045668) |
| 0.1 | 1.7 | GO:0050830 | defense response to Gram-positive bacterium(GO:0050830) |
| 0.1 | 0.2 | GO:0001831 | trophectodermal cellular morphogenesis(GO:0001831) |
| 0.0 | 0.1 | GO:0044340 | neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340) |
| 0.0 | 0.1 | GO:0033629 | negative regulation of cell adhesion mediated by integrin(GO:0033629) |
| 0.0 | 0.3 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.0 | 0.1 | GO:0032571 | response to vitamin K(GO:0032571) |
| 0.0 | 0.1 | GO:0021938 | smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938) |
| 0.0 | 0.3 | GO:0070779 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.0 | 1.1 | GO:0002504 | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504) |
| 0.0 | 0.2 | GO:0021527 | spinal cord association neuron differentiation(GO:0021527) |
| 0.0 | 0.3 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 0.0 | 0.3 | GO:0061101 | neuroendocrine cell differentiation(GO:0061101) |
| 0.0 | 0.3 | GO:0001554 | luteolysis(GO:0001554) |
| 0.0 | 0.6 | GO:0018214 | peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214) |
| 0.0 | 0.2 | GO:0002052 | positive regulation of neuroblast proliferation(GO:0002052) |
| 0.0 | 0.2 | GO:0071168 | protein localization to chromatin(GO:0071168) |
| 0.0 | 0.2 | GO:0046952 | ketone body catabolic process(GO:0046952) |
| 0.0 | 1.5 | GO:0007052 | mitotic spindle organization(GO:0007052) |
| 0.0 | 0.1 | GO:0046984 | regulation of hemoglobin biosynthetic process(GO:0046984) |
| 0.0 | 0.1 | GO:0048311 | mitochondrion distribution(GO:0048311) |
| 0.0 | 0.1 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
| 0.0 | 0.1 | GO:0001919 | regulation of receptor recycling(GO:0001919) |
| 0.0 | 0.4 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
| 0.0 | 1.1 | GO:0000722 | telomere maintenance via recombination(GO:0000722) |
| 0.0 | 0.2 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 0.0 | 0.2 | GO:0051294 | establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294) |
| 0.0 | 0.6 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 0.0 | 0.0 | GO:0007403 | glial cell fate determination(GO:0007403) |
| 0.0 | 0.2 | GO:0033962 | cytoplasmic mRNA processing body assembly(GO:0033962) |
| 0.0 | 0.2 | GO:0045880 | positive regulation of smoothened signaling pathway(GO:0045880) |
| 0.0 | 0.2 | GO:0045943 | positive regulation of transcription from RNA polymerase I promoter(GO:0045943) |
| 0.0 | 0.4 | GO:0034260 | negative regulation of GTPase activity(GO:0034260) |
| 0.0 | 0.9 | GO:0031055 | DNA replication-independent nucleosome assembly(GO:0006336) chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) DNA replication-independent nucleosome organization(GO:0034724) CENP-A containing chromatin organization(GO:0061641) |
| 0.0 | 0.3 | GO:0010507 | negative regulation of autophagy(GO:0010507) |
| 0.0 | 0.2 | GO:0045007 | depurination(GO:0045007) |
| 0.0 | 0.1 | GO:0007093 | mitotic cell cycle checkpoint(GO:0007093) |
| 0.0 | 0.5 | GO:0009220 | pyrimidine ribonucleotide biosynthetic process(GO:0009220) |
| 0.0 | 0.3 | GO:0097061 | dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061) |
| 0.0 | 0.2 | GO:0020027 | hemoglobin metabolic process(GO:0020027) |
| 0.0 | 0.7 | GO:0032011 | ARF protein signal transduction(GO:0032011) |
| 0.0 | 0.6 | GO:0046676 | negative regulation of insulin secretion(GO:0046676) |
| 0.0 | 0.2 | GO:0031124 | RNA 3'-end processing(GO:0031123) mRNA 3'-end processing(GO:0031124) |
| 0.0 | 0.3 | GO:0046835 | carbohydrate phosphorylation(GO:0046835) |
| 0.0 | 0.9 | GO:0071804 | cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805) |
| 0.0 | 0.2 | GO:0009117 | nucleotide metabolic process(GO:0009117) |
| 0.0 | 0.1 | GO:0045603 | positive regulation of endothelial cell differentiation(GO:0045603) |
| 0.0 | 0.2 | GO:0048703 | embryonic viscerocranium morphogenesis(GO:0048703) |
| 0.0 | 0.8 | GO:0001937 | negative regulation of endothelial cell proliferation(GO:0001937) |
| 0.0 | 0.6 | GO:0008625 | extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191) |
| 0.0 | 0.1 | GO:0007288 | sperm axoneme assembly(GO:0007288) |
| 0.0 | 0.1 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 0.0 | 0.4 | GO:0042036 | negative regulation of cytokine biosynthetic process(GO:0042036) |
| 0.0 | 0.2 | GO:0045056 | transcytosis(GO:0045056) |
| 0.0 | 1.0 | GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800) |
| 0.0 | 0.2 | GO:0008089 | anterograde axonal transport(GO:0008089) |
| 0.0 | 0.1 | GO:0006701 | progesterone biosynthetic process(GO:0006701) |
| 0.0 | 0.6 | GO:0007098 | centrosome cycle(GO:0007098) |
| 0.0 | 0.7 | GO:0000060 | protein import into nucleus, translocation(GO:0000060) |
| 0.0 | 0.4 | GO:0045604 | regulation of epidermal cell differentiation(GO:0045604) |
| 0.0 | 0.3 | GO:0043097 | pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097) |
| 0.0 | 4.0 | GO:0043087 | regulation of GTPase activity(GO:0043087) |
| 0.0 | 1.1 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
| 0.0 | 0.1 | GO:0090080 | positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080) |
| 0.0 | 0.2 | GO:0010886 | positive regulation of cholesterol storage(GO:0010886) |
| 0.0 | 0.5 | GO:0006913 | nucleocytoplasmic transport(GO:0006913) |
| 0.0 | 0.1 | GO:0007635 | chemosensory behavior(GO:0007635) |
| 0.0 | 0.1 | GO:0051531 | NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532) |
| 0.0 | 0.1 | GO:0051383 | kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383) |
| 0.0 | 0.2 | GO:0060046 | regulation of acrosome reaction(GO:0060046) |
| 0.0 | 0.5 | GO:0060338 | regulation of type I interferon-mediated signaling pathway(GO:0060338) |
| 0.0 | 0.3 | GO:0002011 | morphogenesis of an epithelial sheet(GO:0002011) |
| 0.0 | 0.2 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.0 | 0.1 | GO:0016075 | rRNA catabolic process(GO:0016075) |
| 0.0 | 0.1 | GO:0021978 | telencephalon regionalization(GO:0021978) |
| 0.0 | 0.3 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.0 | 0.7 | GO:0014047 | glutamate secretion(GO:0014047) |
| 0.0 | 0.5 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.0 | 0.1 | GO:0046541 | saliva secretion(GO:0046541) |
| 0.0 | 0.2 | GO:0009086 | methionine biosynthetic process(GO:0009086) |
| 0.0 | 0.1 | GO:0045992 | negative regulation of embryonic development(GO:0045992) |
| 0.0 | 0.1 | GO:0021759 | globus pallidus development(GO:0021759) forebrain dorsal/ventral pattern formation(GO:0021798) menarche(GO:0042696) |
| 0.0 | 0.3 | GO:0006984 | ER-nucleus signaling pathway(GO:0006984) |
| 0.0 | 0.1 | GO:0008295 | spermidine biosynthetic process(GO:0008295) |
| 0.0 | 0.8 | GO:0050434 | positive regulation of viral transcription(GO:0050434) |
| 0.0 | 0.1 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 0.0 | 0.4 | GO:0006816 | calcium ion transport(GO:0006816) |
| 0.0 | 0.1 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
| 0.0 | 0.2 | GO:0006030 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
| 0.0 | 0.2 | GO:0051103 | DNA ligation involved in DNA repair(GO:0051103) |
| 0.0 | 0.8 | GO:0006338 | chromatin remodeling(GO:0006338) |
| 0.0 | 0.4 | GO:0006289 | nucleotide-excision repair(GO:0006289) |
| 0.0 | 0.1 | GO:0015074 | DNA integration(GO:0015074) |
| 0.0 | 0.0 | GO:0003056 | regulation of vascular smooth muscle contraction(GO:0003056) |
| 0.0 | 0.0 | GO:0060744 | negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147) thelarche(GO:0042695) development of secondary sexual characteristics(GO:0045136) development of secondary female sexual characteristics(GO:0046543) mammary gland branching involved in thelarche(GO:0060744) |
| 0.0 | 0.9 | GO:0051291 | protein heterooligomerization(GO:0051291) |
| 0.0 | 0.2 | GO:0006970 | response to osmotic stress(GO:0006970) |
| 0.0 | 0.1 | GO:0043537 | negative regulation of blood vessel endothelial cell migration(GO:0043537) |
| 0.0 | 0.0 | GO:0051547 | regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549) |
| 0.0 | 0.4 | GO:0050900 | leukocyte migration(GO:0050900) |
| 0.0 | 0.6 | GO:0060333 | interferon-gamma-mediated signaling pathway(GO:0060333) |
| 0.0 | 0.3 | GO:0006099 | tricarboxylic acid cycle(GO:0006099) |
| 0.0 | 0.0 | GO:0010727 | negative regulation of hydrogen peroxide metabolic process(GO:0010727) |
| 0.0 | 0.8 | GO:0007229 | integrin-mediated signaling pathway(GO:0007229) |
| 0.0 | 2.4 | GO:0007601 | visual perception(GO:0007601) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 2.7 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.3 | 1.0 | GO:0031262 | Ndc80 complex(GO:0031262) |
| 0.3 | 5.7 | GO:0042627 | chylomicron(GO:0042627) |
| 0.2 | 1.2 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.2 | 0.9 | GO:0032301 | MutSalpha complex(GO:0032301) |
| 0.2 | 1.4 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.2 | 0.6 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.2 | 0.8 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.2 | 2.2 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.1 | 0.9 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
| 0.1 | 0.4 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.1 | 0.9 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 0.1 | 0.7 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 0.1 | 0.4 | GO:0035189 | Rb-E2F complex(GO:0035189) |
| 0.1 | 0.6 | GO:0019815 | immunoglobulin complex(GO:0019814) B cell receptor complex(GO:0019815) |
| 0.1 | 0.4 | GO:0045257 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
| 0.1 | 0.8 | GO:0005638 | lamin filament(GO:0005638) |
| 0.1 | 1.7 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.1 | 1.1 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
| 0.1 | 0.5 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.1 | 0.7 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 0.1 | 0.4 | GO:0000445 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.1 | 0.7 | GO:1903561 | extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561) |
| 0.1 | 0.7 | GO:0042555 | MCM complex(GO:0042555) |
| 0.1 | 2.6 | GO:0005814 | centriole(GO:0005814) |
| 0.1 | 1.3 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.1 | 0.3 | GO:0071817 | MMXD complex(GO:0071817) |
| 0.1 | 1.1 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.1 | 0.3 | GO:0030893 | meiotic cohesin complex(GO:0030893) |
| 0.1 | 1.5 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.0 | 0.3 | GO:0098984 | asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984) |
| 0.0 | 0.2 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 1.3 | GO:0000299 | obsolete integral to membrane of membrane fraction(GO:0000299) |
| 0.0 | 0.8 | GO:0030136 | clathrin-coated vesicle(GO:0030136) |
| 0.0 | 0.4 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.0 | 0.7 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.0 | 0.2 | GO:0005827 | polar microtubule(GO:0005827) |
| 0.0 | 0.7 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.0 | 0.4 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.0 | 1.1 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 0.8 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.0 | 0.2 | GO:0032807 | DNA ligase IV complex(GO:0032807) |
| 0.0 | 0.1 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.0 | 0.1 | GO:0031310 | intrinsic component of endosome membrane(GO:0031302) intrinsic component of vacuolar membrane(GO:0031310) |
| 0.0 | 1.6 | GO:0098636 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
| 0.0 | 0.9 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.0 | 0.1 | GO:0031301 | integral component of organelle membrane(GO:0031301) |
| 0.0 | 0.3 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 0.0 | 0.1 | GO:0031312 | extrinsic component of organelle membrane(GO:0031312) |
| 0.0 | 0.2 | GO:0042599 | lamellar body(GO:0042599) |
| 0.0 | 0.3 | GO:0032040 | small-subunit processome(GO:0032040) |
| 0.0 | 0.2 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.0 | 0.7 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.0 | 0.1 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
| 0.0 | 0.6 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 0.4 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.0 | 2.0 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 0.1 | GO:0036125 | mitochondrial fatty acid beta-oxidation multienzyme complex(GO:0016507) fatty acid beta-oxidation multienzyme complex(GO:0036125) |
| 0.0 | 1.1 | GO:0005903 | brush border(GO:0005903) |
| 0.0 | 1.6 | GO:0044853 | caveola(GO:0005901) plasma membrane raft(GO:0044853) |
| 0.0 | 1.4 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.0 | 0.2 | GO:0016272 | prefoldin complex(GO:0016272) |
| 0.0 | 0.4 | GO:0019861 | obsolete flagellum(GO:0019861) |
| 0.0 | 0.3 | GO:0014704 | intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291) |
| 0.0 | 0.1 | GO:0042598 | obsolete vesicular fraction(GO:0042598) |
| 0.0 | 0.3 | GO:0032592 | integral component of mitochondrial membrane(GO:0032592) |
| 0.0 | 0.0 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453) |
| 0.0 | 1.5 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 0.6 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.0 | 0.1 | GO:0034361 | very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385) |
| 0.0 | 0.1 | GO:0000300 | obsolete peripheral to membrane of membrane fraction(GO:0000300) |
| 0.0 | 0.2 | GO:0031672 | A band(GO:0031672) |
| 0.0 | 0.2 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.0 | 1.1 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 0.1 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.0 | 0.2 | GO:0031461 | cullin-RING ubiquitin ligase complex(GO:0031461) |
| 0.0 | 0.3 | GO:0016514 | SWI/SNF complex(GO:0016514) |
| 0.0 | 0.1 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.0 | 1.0 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.0 | 0.0 | GO:0031372 | UBC13-MMS2 complex(GO:0031372) |
| 0.0 | 0.0 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 0.0 | 0.4 | GO:0030530 | obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530) |
| 0.0 | 0.0 | GO:0098563 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.0 | 0.1 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.0 | 0.9 | GO:0098857 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 5.7 | GO:0060228 | phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228) |
| 0.4 | 1.1 | GO:0043533 | inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533) |
| 0.3 | 1.3 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
| 0.3 | 1.3 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.2 | 1.6 | GO:0005353 | fructose transmembrane transporter activity(GO:0005353) |
| 0.2 | 0.7 | GO:0031683 | G-protein beta/gamma-subunit complex binding(GO:0031683) |
| 0.2 | 0.9 | GO:0032143 | single thymine insertion binding(GO:0032143) |
| 0.2 | 0.8 | GO:0004727 | prenylated protein tyrosine phosphatase activity(GO:0004727) |
| 0.2 | 0.8 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
| 0.2 | 0.6 | GO:0015193 | L-proline transmembrane transporter activity(GO:0015193) |
| 0.2 | 1.4 | GO:0030911 | TPR domain binding(GO:0030911) |
| 0.2 | 1.2 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
| 0.2 | 1.1 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
| 0.2 | 0.9 | GO:0017159 | pantetheine hydrolase activity(GO:0017159) |
| 0.2 | 0.9 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.2 | 0.8 | GO:0005113 | patched binding(GO:0005113) |
| 0.2 | 0.8 | GO:0009922 | fatty acid elongase activity(GO:0009922) |
| 0.2 | 0.9 | GO:0052654 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 0.2 | 0.5 | GO:0031997 | N-terminal myristoylation domain binding(GO:0031997) |
| 0.2 | 1.5 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.1 | 0.7 | GO:0000827 | inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) |
| 0.1 | 0.4 | GO:0017130 | poly(C) RNA binding(GO:0017130) |
| 0.1 | 0.4 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 0.1 | 0.9 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 0.1 | 0.4 | GO:0035242 | protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242) |
| 0.1 | 1.6 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.1 | 0.8 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 0.1 | 6.0 | GO:0003823 | antigen binding(GO:0003823) |
| 0.1 | 0.3 | GO:0008476 | protein-tyrosine sulfotransferase activity(GO:0008476) |
| 0.1 | 0.4 | GO:0048039 | succinate dehydrogenase activity(GO:0000104) ubiquinone binding(GO:0048039) |
| 0.1 | 0.5 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390) |
| 0.1 | 0.6 | GO:0004439 | phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) |
| 0.1 | 0.6 | GO:0008159 | obsolete positive transcription elongation factor activity(GO:0008159) |
| 0.1 | 0.3 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
| 0.1 | 0.3 | GO:0030197 | extracellular matrix constituent, lubricant activity(GO:0030197) |
| 0.1 | 1.1 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
| 0.1 | 1.4 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.1 | 0.4 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.1 | 0.3 | GO:0008384 | IkappaB kinase activity(GO:0008384) |
| 0.1 | 0.2 | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity(GO:0003858) |
| 0.1 | 0.3 | GO:0004335 | galactokinase activity(GO:0004335) |
| 0.1 | 0.7 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.1 | 3.5 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062) |
| 0.1 | 0.3 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.1 | 0.3 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
| 0.1 | 0.6 | GO:0004873 | asialoglycoprotein receptor activity(GO:0004873) |
| 0.1 | 0.2 | GO:0004813 | alanine-tRNA ligase activity(GO:0004813) |
| 0.1 | 0.2 | GO:0032795 | heterotrimeric G-protein binding(GO:0032795) |
| 0.1 | 0.2 | GO:0004738 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739) |
| 0.1 | 0.2 | GO:0004822 | isoleucine-tRNA ligase activity(GO:0004822) |
| 0.1 | 0.3 | GO:0044020 | histone methyltransferase activity (H4-R3 specific)(GO:0044020) |
| 0.1 | 0.7 | GO:0005131 | growth hormone receptor binding(GO:0005131) |
| 0.1 | 0.4 | GO:0001591 | dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) |
| 0.1 | 1.2 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.1 | 0.3 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
| 0.1 | 0.2 | GO:0000156 | phosphorelay response regulator activity(GO:0000156) |
| 0.1 | 1.0 | GO:0003857 | 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857) |
| 0.1 | 0.6 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 0.0 | 0.1 | GO:0004119 | cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) |
| 0.0 | 1.8 | GO:0016814 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814) |
| 0.0 | 0.9 | GO:0016780 | phosphotransferase activity, for other substituted phosphate groups(GO:0016780) |
| 0.0 | 0.3 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.0 | 0.2 | GO:0034701 | tripeptidase activity(GO:0034701) |
| 0.0 | 0.6 | GO:0003711 | obsolete transcription elongation regulator activity(GO:0003711) |
| 0.0 | 0.3 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 0.0 | 0.2 | GO:0032408 | MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408) |
| 0.0 | 0.9 | GO:0043498 | obsolete cell surface binding(GO:0043498) |
| 0.0 | 0.1 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
| 0.0 | 1.7 | GO:0016620 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620) |
| 0.0 | 0.2 | GO:0004803 | transposase activity(GO:0004803) |
| 0.0 | 0.1 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 0.0 | 1.1 | GO:0070888 | E-box binding(GO:0070888) |
| 0.0 | 2.3 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.0 | 1.1 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.0 | 0.8 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 0.3 | GO:0031369 | translation initiation factor binding(GO:0031369) |
| 0.0 | 0.2 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
| 0.0 | 2.8 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.0 | 0.9 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.0 | 0.1 | GO:0030297 | transmembrane receptor protein tyrosine kinase activator activity(GO:0030297) |
| 0.0 | 0.3 | GO:0070215 | obsolete MDM2 binding(GO:0070215) |
| 0.0 | 1.5 | GO:0016836 | hydro-lyase activity(GO:0016836) |
| 0.0 | 1.0 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 0.1 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.0 | 0.1 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
| 0.0 | 1.1 | GO:0015026 | coreceptor activity(GO:0015026) |
| 0.0 | 0.1 | GO:0003988 | acetyl-CoA C-acyltransferase activity(GO:0003988) |
| 0.0 | 0.2 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) bicarbonate transmembrane transporter activity(GO:0015106) |
| 0.0 | 0.5 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.0 | 0.1 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416) |
| 0.0 | 0.2 | GO:0004046 | aminoacylase activity(GO:0004046) |
| 0.0 | 1.7 | GO:0001948 | glycoprotein binding(GO:0001948) |
| 0.0 | 0.3 | GO:0070053 | thrombospondin receptor activity(GO:0070053) |
| 0.0 | 0.3 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.0 | 0.3 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.0 | 0.6 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.0 | 0.3 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.0 | 0.2 | GO:0070700 | BMP receptor binding(GO:0070700) |
| 0.0 | 0.2 | GO:0016723 | oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723) |
| 0.0 | 0.1 | GO:0045029 | UDP-activated nucleotide receptor activity(GO:0045029) |
| 0.0 | 0.3 | GO:0042301 | phosphate ion binding(GO:0042301) |
| 0.0 | 0.1 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
| 0.0 | 0.1 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
| 0.0 | 0.9 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
| 0.0 | 0.4 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.0 | 0.1 | GO:0008502 | melatonin receptor activity(GO:0008502) |
| 0.0 | 0.2 | GO:0003701 | obsolete RNA polymerase I transcription factor activity(GO:0003701) |
| 0.0 | 0.6 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.0 | 0.4 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) |
| 0.0 | 0.3 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
| 0.0 | 0.1 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 0.0 | 0.2 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 0.0 | 0.6 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.0 | 0.2 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.0 | 0.1 | GO:0008967 | phosphoglycolate phosphatase activity(GO:0008967) |
| 0.0 | 0.1 | GO:0016944 | obsolete RNA polymerase II transcription elongation factor activity(GO:0016944) |
| 0.0 | 0.7 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
| 0.0 | 0.2 | GO:0060590 | ATPase regulator activity(GO:0060590) |
| 0.0 | 0.3 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.0 | 0.2 | GO:0004117 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) |
| 0.0 | 0.2 | GO:0047429 | nucleoside-triphosphate diphosphatase activity(GO:0047429) |
| 0.0 | 2.3 | GO:0017016 | Ras GTPase binding(GO:0017016) |
| 0.0 | 1.0 | GO:0016811 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811) |
| 0.0 | 0.3 | GO:0000146 | microfilament motor activity(GO:0000146) |
| 0.0 | 0.4 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.0 | 2.8 | GO:0003702 | obsolete RNA polymerase II transcription factor activity(GO:0003702) |
| 0.0 | 0.1 | GO:0008179 | adenylate cyclase binding(GO:0008179) protein kinase A regulatory subunit binding(GO:0034237) |
| 0.0 | 0.1 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 0.0 | 0.1 | GO:0004766 | spermidine synthase activity(GO:0004766) |
| 0.0 | 0.2 | GO:0004568 | chitinase activity(GO:0004568) |
| 0.0 | 0.2 | GO:0000339 | RNA cap binding(GO:0000339) |
| 0.0 | 0.2 | GO:0005030 | neurotrophin receptor activity(GO:0005030) |
| 0.0 | 0.1 | GO:0015174 | basic amino acid transmembrane transporter activity(GO:0015174) |
| 0.0 | 0.4 | GO:0019003 | GDP binding(GO:0019003) |
| 0.0 | 0.3 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.0 | 0.1 | GO:0008504 | monoamine transmembrane transporter activity(GO:0008504) |
| 0.0 | 1.1 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.0 | 1.5 | GO:0001071 | nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700) |
| 0.0 | 0.2 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.0 | 0.1 | GO:0030528 | obsolete transcription regulator activity(GO:0030528) |
| 0.0 | 0.1 | GO:0050780 | dopamine receptor binding(GO:0050780) |
| 0.0 | 0.2 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
| 0.0 | 0.3 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 0.0 | 0.4 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.0 | 5.7 | GO:0004674 | protein serine/threonine kinase activity(GO:0004674) |
| 0.0 | 0.9 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 0.1 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
| 0.0 | 0.1 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.7 | ST_IL_13_PATHWAY | Interleukin 13 (IL-13) Pathway |
| 0.1 | 1.3 | SA_FAS_SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 0.0 | 2.0 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.0 | 0.6 | SA_B_CELL_RECEPTOR_COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.0 | 0.3 | SA_PTEN_PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
