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Motif ID: GTF2I

Z-value: 1.070

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr5_+_92919043	2.450	ENST00000327111.3	NR2F1	nuclear receptor subfamily 2, group F, member 1
chr2_+_128175997	1.918	ENST00000234071.3 ENST00000429925.1 ENST00000442644.1 ENST00000453608.2	PROC	protein C (inactivator of coagulation factors Va and VIIIa)
chr14_-_54423529	1.901	ENST00000245451.4 ENST00000559087.1	BMP4	bone morphogenetic protein 4
chr16_+_69599899	1.556	ENST00000567239.1	NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive
chr10_+_114710211	1.551	ENST00000349937.2 ENST00000369397.4	TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)
chr16_+_69600058	1.528	ENST00000393742.2	NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive
chr8_+_97506033	1.473	ENST00000518385.1	SDC2	syndecan 2
chrX_-_133119476	1.393	ENST00000543339.1	GPC3	glypican 3
chr2_-_39664405	1.385	ENST00000341681.5 ENST00000263881.3	MAP4K3	mitogen-activated protein kinase kinase kinase kinase 3
chrX_-_133119670	1.382	ENST00000394299.2	GPC3	glypican 3
chr5_-_121413974	1.377	ENST00000231004.4	LOX	lysyl oxidase
chr16_-_52580920	1.344	ENST00000219746.9	TOX3	TOX high mobility group box family member 3
chr19_+_35629702	1.336	ENST00000351325.4	FXYD1	FXYD domain containing ion transport regulator 1
chrX_-_133119895	1.330	ENST00000370818.3	GPC3	glypican 3
chr10_+_114709999	1.282	ENST00000355995.4 ENST00000545257.1 ENST00000543371.1 ENST00000536810.1 ENST00000355717.4 ENST00000538897.1 ENST00000534894.1	TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)
chr11_-_46142615	1.260	ENST00000529734.1 ENST00000323180.6	PHF21A	PHD finger protein 21A
chr7_+_100770328	1.236	ENST00000223095.4 ENST00000445463.2	SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr15_-_61521495	1.215	ENST00000335670.6	RORA	RAR-related orphan receptor A
chr5_-_111092930	1.177	ENST00000257435.7	NREP	neuronal regeneration related protein
chr16_+_69599861	1.142	ENST00000354436.2	NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive
chr19_+_35630022	1.081	ENST00000589209.1	FXYD1	FXYD domain containing ion transport regulator 1
chr4_-_16900242	1.064	ENST00000502640.1 ENST00000506732.1	LDB2	LIM domain binding 2
chr2_-_21266935	1.051	ENST00000233242.1	APOB	apolipoprotein B
chr1_+_183605200	1.039	ENST00000304685.4	RGL1	ral guanine nucleotide dissociation stimulator-like 1
chr1_-_92351769	1.013	ENST00000212355.4	TGFBR3	transforming growth factor, beta receptor III
chr10_+_120967072	1.005	ENST00000392870.2	GRK5	G protein-coupled receptor kinase 5
chrX_-_130423386	1.004	ENST00000370903.3	IGSF1	immunoglobulin superfamily, member 1
chr12_-_115121962	0.981	ENST00000349155.2	TBX3	T-box 3
chr4_-_16900217	0.976	ENST00000441778.2	LDB2	LIM domain binding 2
chr14_+_21538517	0.967	ENST00000298693.3	ARHGEF40	Rho guanine nucleotide exchange factor (GEF) 40
chr4_-_16900410	0.965	ENST00000304523.5	LDB2	LIM domain binding 2
chr12_+_56473628	0.956	ENST00000549282.1 ENST00000549061.1 ENST00000267101.3	ERBB3	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr5_-_111093167	0.948	ENST00000446294.2 ENST00000419114.2	NREP	neuronal regeneration related protein
chr14_+_21538429	0.944	ENST00000298694.4 ENST00000555038.1	ARHGEF40	Rho guanine nucleotide exchange factor (GEF) 40
chr14_+_32546274	0.933	ENST00000396582.2	ARHGAP5	Rho GTPase activating protein 5
chr2_+_54683419	0.917	ENST00000356805.4	SPTBN1	spectrin, beta, non-erythrocytic 1
chr2_+_219264466	0.916	ENST00000273062.2	CTDSP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr15_-_60884706	0.910	ENST00000449337.2	RORA	RAR-related orphan receptor A
chr3_-_8693755	0.897	ENST00000341795.3	SSUH2	ssu-2 homolog (C. elegans)
chrX_-_130423240	0.896	ENST00000370910.1 ENST00000370901.4	IGSF1	immunoglobulin superfamily, member 1
chr6_+_31620191	0.889	ENST00000375918.2 ENST00000375920.4	APOM	apolipoprotein M
chr17_+_27369918	0.868	ENST00000323372.4	PIPOX	pipecolic acid oxidase
chrX_+_115567767	0.845	ENST00000371900.4	SLC6A14	solute carrier family 6 (amino acid transporter), member 14
chr15_-_37392703	0.844	ENST00000382766.2 ENST00000444725.1	MEIS2	Meis homeobox 2
chr4_-_16900184	0.834	ENST00000515064.1	LDB2	LIM domain binding 2
chrX_-_20284958	0.826	ENST00000379565.3	RPS6KA3	ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr14_+_32546485	0.818	ENST00000345122.3 ENST00000432921.1 ENST00000433497.1	ARHGAP5	Rho GTPase activating protein 5
chr7_-_22233442	0.817	ENST00000401957.2	RAPGEF5	Rap guanine nucleotide exchange factor (GEF) 5
chrX_-_130423200	0.797	ENST00000361420.3	IGSF1	immunoglobulin superfamily, member 1
chr2_+_62933001	0.795	ENST00000263991.5 ENST00000354487.3	EHBP1	EH domain binding protein 1
chr19_+_45417504	0.791	ENST00000588750.1 ENST00000588802.1	APOC1	apolipoprotein C-I
chr8_+_30241934	0.780	ENST00000538486.1	RBPMS	RNA binding protein with multiple splicing
chr16_-_29910853	0.770	ENST00000308713.5	SEZ6L2	seizure related 6 homolog (mouse)-like 2
chr1_+_169077172	0.753	ENST00000499679.3	ATP1B1	ATPase, Na+/K+ transporting, beta 1 polypeptide
chr4_+_185395947	0.739	ENST00000605834.1	RP11-326I11.3	RP11-326I11.3
chr5_-_111092873	0.734	ENST00000509025.1 ENST00000515855.1	NREP	neuronal regeneration related protein
chr1_+_203444887	0.731	ENST00000343110.2	PRELP	proline/arginine-rich end leucine-rich repeat protein
chr5_-_111093340	0.730	ENST00000508870.1	NREP	neuronal regeneration related protein
chr8_+_28748099	0.716	ENST00000519047.1	HMBOX1	homeobox containing 1
chr22_+_38201114	0.696	ENST00000340857.2	H1F0	H1 histone family, member 0
chr1_+_169075554	0.683	ENST00000367815.4	ATP1B1	ATPase, Na+/K+ transporting, beta 1 polypeptide
chr7_-_23510086	0.678	ENST00000258729.3	IGF2BP3	insulin-like growth factor 2 mRNA binding protein 3
chr6_+_37137939	0.675	ENST00000373509.5	PIM1	pim-1 oncogene
chr8_+_26371763	0.667	ENST00000521913.1	DPYSL2	dihydropyrimidinase-like 2
chr4_-_185395672	0.666	ENST00000393593.3	IRF2	interferon regulatory factor 2
chr15_-_37392086	0.656	ENST00000561208.1	MEIS2	Meis homeobox 2
chr11_-_2160180	0.639	ENST00000381406.4	IGF2	insulin-like growth factor 2 (somatomedin A)
chr8_-_134584092	0.632	ENST00000522652.1	ST3GAL1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr19_+_18496957	0.619	ENST00000252809.3	GDF15	growth differentiation factor 15
chr20_+_34742650	0.617	ENST00000373945.1 ENST00000338074.2	EPB41L1	erythrocyte membrane protein band 4.1-like 1
chr8_-_134584152	0.609	ENST00000521180.1 ENST00000517668.1 ENST00000319914.5	ST3GAL1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr11_-_86666427	0.607	ENST00000531380.1	FZD4	frizzled family receptor 4
chr6_+_31865552	0.603	ENST00000469372.1 ENST00000497706.1	C2	complement component 2
chr16_-_88717482	0.599	ENST00000261623.3	CYBA	cytochrome b-245, alpha polypeptide
chr12_+_12870055	0.594	ENST00000228872.4	CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)
chr17_-_41623075	0.590	ENST00000545089.1	ETV4	ets variant 4
chr2_-_174828892	0.589	ENST00000418194.2	SP3	Sp3 transcription factor
chr7_-_27170352	0.580	ENST00000428284.2 ENST00000360046.5	HOXA4	homeobox A4
chr6_+_43739697	0.568	ENST00000230480.6	VEGFA	vascular endothelial growth factor A
chr8_+_30241995	0.564	ENST00000397323.4 ENST00000339877.4 ENST00000320203.4 ENST00000287771.5	RBPMS	RNA binding protein with multiple splicing
chr17_-_36904437	0.551	ENST00000585100.1 ENST00000360797.2 ENST00000578109.1 ENST00000579882.1	PCGF2	polycomb group ring finger 2
chr8_+_21912328	0.541	ENST00000432128.1 ENST00000443491.2 ENST00000517600.1 ENST00000523782.2	DMTN	dematin actin binding protein
chr5_+_36876833	0.539	ENST00000282516.8 ENST00000448238.2	NIPBL	Nipped-B homolog (Drosophila)
chr11_+_7506713	0.537	ENST00000329293.3 ENST00000534244.1	OLFML1	olfactomedin-like 1
chr5_+_176513868	0.534	ENST00000292408.4	FGFR4	fibroblast growth factor receptor 4
chr6_-_32157947	0.526	ENST00000375050.4	PBX2	pre-B-cell leukemia homeobox 2
chr2_+_46926326	0.525	ENST00000394861.2	SOCS5	suppressor of cytokine signaling 5
chr1_+_82266053	0.522	ENST00000370715.1 ENST00000370713.1 ENST00000319517.6 ENST00000370717.2 ENST00000394879.1 ENST00000271029.4 ENST00000335786.5	LPHN2	latrophilin 2
chr19_-_36297348	0.519	ENST00000589835.1	PRODH2	proline dehydrogenase (oxidase) 2
chrX_+_198129	0.516	ENST00000381663.3	PLCXD1	phosphatidylinositol-specific phospholipase C, X domain containing 1
chr1_-_154193009	0.516	ENST00000368518.1 ENST00000368519.1 ENST00000368521.5	C1orf43	chromosome 1 open reading frame 43
chr17_-_41623259	0.514	ENST00000538265.1 ENST00000591713.1	ETV4	ets variant 4
chrX_+_105969893	0.508	ENST00000255499.2	RNF128	ring finger protein 128, E3 ubiquitin protein ligase
chr17_-_36891830	0.508	ENST00000578487.1	PCGF2	polycomb group ring finger 2
chr7_+_29234101	0.497	ENST00000435288.2	CHN2	chimerin 2
chr20_-_33413416	0.496	ENST00000359003.2	NCOA6	nuclear receptor coactivator 6
chr8_+_28747884	0.492	ENST00000287701.10 ENST00000444075.1 ENST00000403668.2 ENST00000519662.1 ENST00000558662.1 ENST00000523613.1 ENST00000560599.1 ENST00000397358.3	HMBOX1	homeobox containing 1
chr6_-_131384373	0.491	ENST00000392427.3 ENST00000525271.1 ENST00000527411.1	EPB41L2	erythrocyte membrane protein band 4.1-like 2
chr9_-_129884902	0.487	ENST00000373417.1	ANGPTL2	angiopoietin-like 2
chr1_+_15480197	0.483	ENST00000400796.3 ENST00000434578.2 ENST00000376008.2	TMEM51	transmembrane protein 51
chr17_+_73472575	0.483	ENST00000375248.5	KIAA0195	KIAA0195
chr9_-_129885010	0.476	ENST00000373425.3	ANGPTL2	angiopoietin-like 2
chr16_+_29472707	0.469	ENST00000565290.1	SULT1A4	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr1_-_20812690	0.466	ENST00000375078.3	CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr14_+_23775971	0.466	ENST00000250405.5	BCL2L2	BCL2-like 2
chr3_+_54156570	0.463	ENST00000415676.2	CACNA2D3	calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr17_-_41623009	0.462	ENST00000393664.2	ETV4	ets variant 4
chr5_-_149535421	0.462	ENST00000261799.4	PDGFRB	platelet-derived growth factor receptor, beta polypeptide
chr10_+_114710425	0.454	ENST00000352065.5 ENST00000369395.1	TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)
chr2_+_36582857	0.449	ENST00000280527.2	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr17_-_41623691	0.447	ENST00000545954.1	ETV4	ets variant 4
chr7_+_29234028	0.446	ENST00000222792.6	CHN2	chimerin 2
chr14_-_89883412	0.445	ENST00000557258.1	FOXN3	forkhead box N3
chr14_+_68086515	0.443	ENST00000261783.3	ARG2	arginase 2
chr17_+_40834580	0.443	ENST00000264638.4	CNTNAP1	contactin associated protein 1
chr18_+_32556892	0.438	ENST00000591734.1 ENST00000413393.1 ENST00000589180.1 ENST00000587359.1	MAPRE2	microtubule-associated protein, RP/EB family, member 2
chr3_-_79068594	0.437	ENST00000436010.2	ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr17_-_7155274	0.436	ENST00000318988.6 ENST00000575783.1 ENST00000573600.1	CTDNEP1	CTD nuclear envelope phosphatase 1
chr6_-_131384347	0.428	ENST00000530481.1	EPB41L2	erythrocyte membrane protein band 4.1-like 2
chr19_-_36297632	0.426	ENST00000588266.2	PRODH2	proline dehydrogenase (oxidase) 2
chr11_-_70507901	0.422	ENST00000449833.2 ENST00000357171.3 ENST00000449116.2	SHANK2	SH3 and multiple ankyrin repeat domains 2
chr8_-_38325219	0.422	ENST00000533668.1 ENST00000413133.2 ENST00000397108.4 ENST00000526742.1 ENST00000525001.1 ENST00000425967.3 ENST00000529552.1 ENST00000397113.2	FGFR1	fibroblast growth factor receptor 1
chr3_+_54156664	0.421	ENST00000474759.1 ENST00000288197.5	CACNA2D3	calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr5_+_176513895	0.418	ENST00000503708.1 ENST00000393648.2 ENST00000514472.1 ENST00000502906.1 ENST00000292410.3 ENST00000510911.1	FGFR4	fibroblast growth factor receptor 4
chr14_+_23776024	0.417	ENST00000557236.1 ENST00000557579.1 ENST00000553781.1 ENST00000556100.1	BCL2L2 BCL2L2-PABPN1	BCL2-like 2 BCL2L2-PABPN1 readthrough
chr4_+_129730779	0.414	ENST00000226319.6	PHF17	jade family PHD finger 1
chr19_+_56652686	0.413	ENST00000592949.1	ZNF444	zinc finger protein 444
chr12_+_102271129	0.412	ENST00000258534.8	DRAM1	DNA-damage regulated autophagy modulator 1
chrX_+_129116586	0.407	ENST00000218147.7 ENST00000303743.5 ENST00000359304.2	BCORL1	BCL6 corepressor-like 1
chr1_+_86046433	0.404	ENST00000451137.2	CYR61	cysteine-rich, angiogenic inducer, 61
chr6_-_131384412	0.404	ENST00000445890.2 ENST00000368128.2 ENST00000337057.3	EPB41L2	erythrocyte membrane protein band 4.1-like 2
chr6_-_52860171	0.399	ENST00000370963.4	GSTA4	glutathione S-transferase alpha 4
chr16_+_85645007	0.390	ENST00000405402.2	GSE1	Gse1 coiled-coil protein
chr1_+_10271674	0.388	ENST00000377086.1	KIF1B	kinesin family member 1B
chr17_-_41623716	0.388	ENST00000319349.5	ETV4	ets variant 4
chr1_+_151043070	0.385	ENST00000368918.3 ENST00000368917.1	GABPB2	GA binding protein transcription factor, beta subunit 2
chr19_+_56652556	0.385	ENST00000337080.3	ZNF444	zinc finger protein 444
chr3_+_43328004	0.385	ENST00000454177.1 ENST00000429705.2 ENST00000296088.7 ENST00000437827.1	SNRK	SNF related kinase
chr1_+_167190066	0.384	ENST00000367866.2 ENST00000429375.2 ENST00000452019.1 ENST00000420254.3 ENST00000541643.3	POU2F1	POU class 2 homeobox 1
chr20_+_306177	0.380	ENST00000544632.1	SOX12	SRY (sex determining region Y)-box 12
chr6_-_111804905	0.378	ENST00000358835.3 ENST00000435970.1	REV3L	REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr6_+_114178512	0.376	ENST00000368635.4	MARCKS	myristoylated alanine-rich protein kinase C substrate
chr17_-_40540586	0.372	ENST00000264657.5	STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)
chr14_-_65409438	0.368	ENST00000557049.1	GPX2	glutathione peroxidase 2 (gastrointestinal)
chr18_-_51750948	0.368	ENST00000583046.1 ENST00000398398.2	MBD2	methyl-CpG binding domain protein 2
chr12_-_106641728	0.368	ENST00000378026.4	CKAP4	cytoskeleton-associated protein 4
chr6_-_32143828	0.367	ENST00000412465.2 ENST00000375107.3	AGPAT1	1-acylglycerol-3-phosphate O-acyltransferase 1
chr2_+_159313452	0.365	ENST00000389757.3 ENST00000389759.3	PKP4	plakophilin 4
chr12_-_6798616	0.364	ENST00000355772.4 ENST00000417772.3 ENST00000396801.3 ENST00000396799.2	ZNF384	zinc finger protein 384
chr6_-_112575912	0.363	ENST00000522006.1 ENST00000230538.7 ENST00000519932.1	LAMA4	laminin, alpha 4
chr1_+_27022839	0.361	ENST00000457599.2	ARID1A	AT rich interactive domain 1A (SWI-like)
chr18_-_500692	0.360	ENST00000400256.3	COLEC12	collectin sub-family member 12
chr12_-_122018859	0.358	ENST00000536437.1 ENST00000377071.4 ENST00000538046.2	KDM2B	lysine (K)-specific demethylase 2B
chr2_+_46926048	0.356	ENST00000306503.5	SOCS5	suppressor of cytokine signaling 5
chr2_+_8822113	0.348	ENST00000396290.1 ENST00000331129.3	ID2	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr3_-_50360192	0.344	ENST00000442581.1 ENST00000447092.1 ENST00000357750.4	HYAL2	hyaluronoglucosaminidase 2
chr5_-_111093081	0.343	ENST00000453526.2 ENST00000509427.1	NREP	neuronal regeneration related protein
chr22_+_45898712	0.340	ENST00000455233.1 ENST00000348697.2 ENST00000402984.3 ENST00000262722.7 ENST00000327858.6 ENST00000442170.2 ENST00000340923.5 ENST00000439835.1	FBLN1	fibulin 1
chr8_+_37654693	0.340	ENST00000412232.2	GPR124	G protein-coupled receptor 124
chr6_+_33378738	0.339	ENST00000374512.3 ENST00000374516.3	PHF1	PHD finger protein 1
chr1_-_235491462	0.339	ENST00000418304.1 ENST00000264183.3 ENST00000349213.3	ARID4B	AT rich interactive domain 4B (RBP1-like)
chr8_-_57123815	0.338	ENST00000316981.3 ENST00000423799.2 ENST00000429357.2	PLAG1	pleiomorphic adenoma gene 1
chr4_+_129730947	0.338	ENST00000452328.2 ENST00000504089.1	PHF17	jade family PHD finger 1
chr20_-_3154162	0.338	ENST00000360342.3	LZTS3	Homo sapiens leucine zipper, putative tumor suppressor family member 3 (LZTS3), mRNA.
chr1_-_109935819	0.337	ENST00000538502.1	SORT1	sortilin 1
chr1_+_214161854	0.336	ENST00000435016.1	PROX1	prospero homeobox 1
chr5_+_71403061	0.335	ENST00000512974.1 ENST00000296755.7	MAP1B	microtubule-associated protein 1B
chr6_-_112575687	0.334	ENST00000521398.1 ENST00000424408.2 ENST00000243219.3	LAMA4	laminin, alpha 4
chr16_-_73082274	0.331	ENST00000268489.5	ZFHX3	zinc finger homeobox 3
chr10_-_15413035	0.331	ENST00000378116.4 ENST00000455654.1	FAM171A1	family with sequence similarity 171, member A1
chr12_+_53845879	0.329	ENST00000359282.5 ENST00000603815.1 ENST00000447282.1 ENST00000437231.1 ENST00000549863.1 ENST00000359462.5 ENST00000550520.2 ENST00000546463.1 ENST00000552296.2	PCBP2	poly(rC) binding protein 2
chr12_+_57522258	0.329	ENST00000553277.1 ENST00000243077.3	LRP1	low density lipoprotein receptor-related protein 1
chr6_-_16761678	0.329	ENST00000244769.4 ENST00000436367.1	ATXN1	ataxin 1
chrX_-_70473957	0.329	ENST00000373984.3 ENST00000314425.5 ENST00000373982.1	ZMYM3	zinc finger, MYM-type 3
chr17_-_7154984	0.328	ENST00000574322.1	CTDNEP1	CTD nuclear envelope phosphatase 1
chr22_+_38609538	0.327	ENST00000407965.1	MAFF	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr2_-_176032843	0.327	ENST00000392544.1 ENST00000409499.1 ENST00000426833.3 ENST00000392543.2 ENST00000538946.1 ENST00000487334.2 ENST00000409833.1 ENST00000409635.1 ENST00000264110.2 ENST00000345739.5	ATF2	activating transcription factor 2
chr16_+_29819446	0.327	ENST00000568282.1	MAZ	MYC-associated zinc finger protein (purine-binding transcription factor)
chr19_+_14544099	0.327	ENST00000242783.6 ENST00000586557.1 ENST00000590097.1	PKN1	protein kinase N1
chr1_+_205473720	0.326	ENST00000429964.2 ENST00000506784.1 ENST00000360066.2	CDK18	cyclin-dependent kinase 18
chr10_+_31608054	0.326	ENST00000320985.10 ENST00000361642.5 ENST00000560721.2 ENST00000558440.1 ENST00000424869.1 ENST00000542815.3	ZEB1	zinc finger E-box binding homeobox 1
chr3_+_171758344	0.323	ENST00000336824.4 ENST00000423424.1	FNDC3B	fibronectin type III domain containing 3B
chr18_+_46065483	0.322	ENST00000382998.4	CTIF	CBP80/20-dependent translation initiation factor
chr14_+_24837226	0.322	ENST00000554050.1 ENST00000554903.1 ENST00000554779.1 ENST00000250373.4 ENST00000553708.1	NFATC4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
chr14_-_65409502	0.320	ENST00000389614.5	GPX2	glutathione peroxidase 2 (gastrointestinal)
chr2_+_42396574	0.318	ENST00000401738.3	EML4	echinoderm microtubule associated protein like 4
chrX_+_49644470	0.318	ENST00000508866.2	USP27X	ubiquitin specific peptidase 27, X-linked
chr17_-_46608272	0.317	ENST00000577092.1 ENST00000239174.6	HOXB1	homeobox B1
chr16_-_10674528	0.317	ENST00000359543.3	EMP2	epithelial membrane protein 2
chr2_+_42396472	0.316	ENST00000318522.5 ENST00000402711.2	EML4	echinoderm microtubule associated protein like 4
chr14_+_23776167	0.315	ENST00000554635.1 ENST00000557008.1	BCL2L2 BCL2L2-PABPN1	BCL2-like 2 BCL2L2-PABPN1 readthrough
chr2_-_136743169	0.313	ENST00000264161.4	DARS	aspartyl-tRNA synthetase
chr17_-_47755436	0.312	ENST00000505581.1 ENST00000514121.1 ENST00000393328.2 ENST00000509079.1 ENST00000393331.3 ENST00000347630.2 ENST00000504102.1	SPOP	speckle-type POZ protein
chr15_+_90544532	0.312	ENST00000268154.4	ZNF710	zinc finger protein 710
chr19_-_2015699	0.310	ENST00000255608.4	BTBD2	BTB (POZ) domain containing 2
chr7_-_137686791	0.310	ENST00000452463.1 ENST00000330387.6 ENST00000456390.1	CREB3L2	cAMP responsive element binding protein 3-like 2
chr8_+_28748765	0.310	ENST00000355231.5	HMBOX1	homeobox containing 1
chr12_-_81331697	0.306	ENST00000552864.1	LIN7A	lin-7 homolog A (C. elegans)
chr2_+_101618691	0.305	ENST00000409000.1 ENST00000409028.4 ENST00000409320.3 ENST00000409733.1 ENST00000409650.1 ENST00000409038.1	RPL31	ribosomal protein L31
chr11_-_65640198	0.305	ENST00000528176.1	EFEMP2	EGF containing fibulin-like extracellular matrix protein 2

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	4.1	GO:0072180	mesonephric duct morphogenesis(GO:0072180)
0.9	3.5	GO:0048619	embryonic hindgut morphogenesis(GO:0048619)
0.6	1.9	GO:0072178	nephric duct morphogenesis(GO:0072178)
0.4	0.9	GO:0010159	specification of organ position(GO:0010159)
0.4	1.3	GO:0001300	chronological cell aging(GO:0001300)
0.3	1.0	GO:0060318	definitive erythrocyte differentiation(GO:0060318)
0.3	0.9	GO:0043371	negative regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043371) negative regulation of T-helper cell differentiation(GO:0045623) negative regulation of CD4-positive, alpha-beta T cell activation(GO:2000515)
0.3	0.8	GO:0021837	motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) regulation of mesodermal cell fate specification(GO:0042661) lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378) regulation of mesoderm development(GO:2000380)
0.3	1.1	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.3	0.3	GO:0003344	pericardium morphogenesis(GO:0003344)
0.2	2.7	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.2	0.9	GO:0034442	plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.2	0.6	GO:0061298	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.2	0.8	GO:0010900	regulation of phosphatidylcholine catabolic process(GO:0010899) negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.2	0.6	GO:0097237	cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.2	0.6	GO:0002575	basophil chemotaxis(GO:0002575)
0.2	0.6	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.2	0.6	GO:0055005	optic placode formation involved in camera-type eye formation(GO:0046619) venous blood vessel morphogenesis(GO:0048845) ventricular cardiac myofibril assembly(GO:0055005) embryonic retina morphogenesis in camera-type eye(GO:0060059) regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.2	0.9	GO:0007182	common-partner SMAD protein phosphorylation(GO:0007182)
0.2	0.7	GO:0050928	negative regulation of positive chemotaxis(GO:0050928)
0.2	0.9	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.2	1.4	GO:0048251	elastic fiber assembly(GO:0048251)
0.2	0.7	GO:0009609	response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.2	0.5	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.2	0.9	GO:0006562	proline catabolic process(GO:0006562)
0.2	0.6	GO:0033197	response to vitamin E(GO:0033197)
0.1	0.9	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1	0.7	GO:0003093	regulation of glomerular filtration(GO:0003093) glomerular filtration(GO:0003094) renal filtration(GO:0097205) regulation of renal system process(GO:0098801)
0.1	0.5	GO:0034086	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.1	0.4	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1	0.4	GO:0021823	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.1	0.4	GO:0019521	aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.1	1.9	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1	0.2	GO:0046732	induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by virus of host immune response(GO:0075528)
0.1	1.2	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1	0.3	GO:0021570	rhombomere 4 development(GO:0021570) facial nucleus development(GO:0021754)
0.1	1.0	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.1	0.4	GO:0042986	positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.1	0.4	GO:0090161	Golgi ribbon formation(GO:0090161)
0.1	0.3	GO:0046292	formaldehyde metabolic process(GO:0046292)
0.1	0.3	GO:0014887	muscle hypertrophy in response to stress(GO:0003299) response to stimulus involved in regulation of muscle adaptation(GO:0014874) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.1	0.9	GO:0046653	tetrahydrofolate metabolic process(GO:0046653)
0.1	0.8	GO:0071692	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	0.7	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.1	0.7	GO:0043982	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1	0.3	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.1	0.2	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.1	0.9	GO:0060716	labyrinthine layer blood vessel development(GO:0060716)
0.1	0.3	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.1	0.4	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.1	0.2	GO:0060689	cell differentiation involved in salivary gland development(GO:0060689)
0.1	0.2	GO:0070171	negative regulation of tooth mineralization(GO:0070171)
0.1	0.5	GO:0019985	translesion synthesis(GO:0019985)
0.1	0.3	GO:0015891	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1	0.5	GO:0006896	Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.1	0.3	GO:0071699	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1	0.4	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.1	0.4	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.1	0.2	GO:0070734	histone H3-K27 methylation(GO:0070734)
0.1	0.7	GO:0031017	exocrine pancreas development(GO:0031017)
0.1	0.4	GO:0031657	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.1	0.2	GO:0061188	regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1	1.5	GO:0031000	response to caffeine(GO:0031000)
0.1	0.1	GO:0048714	positive regulation of oligodendrocyte differentiation(GO:0048714)
0.1	0.1	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.1	0.2	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1	0.2	GO:0060539	diaphragm development(GO:0060539)
0.1	0.1	GO:0044340	canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.1	0.3	GO:0046069	cGMP catabolic process(GO:0046069)
0.1	0.4	GO:0008045	motor neuron axon guidance(GO:0008045)
0.1	0.2	GO:0071894	histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1	0.3	GO:0010875	positive regulation of cholesterol efflux(GO:0010875)
0.1	0.2	GO:0045218	zonula adherens maintenance(GO:0045218)
0.1	1.9	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.1	0.3	GO:0032754	positive regulation of interleukin-13 production(GO:0032736) positive regulation of interleukin-5 production(GO:0032754)
0.1	0.2	GO:0002158	osteoclast proliferation(GO:0002158) regulation of osteoblast proliferation(GO:0033688)
0.0	0.5	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.1	GO:0014028	notochord formation(GO:0014028)
0.0	0.3	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.2	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.0	0.2	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	3.8	GO:0007588	excretion(GO:0007588)
0.0	0.4	GO:0060736	prostate gland growth(GO:0060736)
0.0	0.3	GO:0009450	gamma-aminobutyric acid catabolic process(GO:0009450)
0.0	4.4	GO:0034339	obsolete regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor(GO:0034339)
0.0	0.2	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.0	1.0	GO:0060056	mammary gland involution(GO:0060056)
0.0	0.3	GO:0042074	cell migration involved in gastrulation(GO:0042074)
0.0	0.1	GO:0042339	keratan sulfate metabolic process(GO:0042339)
0.0	0.0	GO:0071504	response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
0.0	0.1	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.4	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.1	GO:0048670	regulation of collateral sprouting(GO:0048670)
0.0	0.2	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0	0.3	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.2	GO:0060676	ureteric bud formation(GO:0060676) mesonephric tubule formation(GO:0072172)
0.0	0.1	GO:0001830	trophectodermal cell fate commitment(GO:0001830)
0.0	0.2	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.3	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.1	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	2.5	GO:0006821	chloride transport(GO:0006821)
0.0	0.6	GO:0051319	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.1	GO:0048935	peripheral nervous system neuron development(GO:0048935)
0.0	0.3	GO:0006027	glycosaminoglycan catabolic process(GO:0006027)
0.0	0.2	GO:0030644	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.3	GO:0046146	tetrahydrobiopterin metabolic process(GO:0046146)
0.0	0.3	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.2	GO:0002036	regulation of L-glutamate transport(GO:0002036)
0.0	0.2	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.3	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.1	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367) regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0	0.2	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.3	GO:0031639	plasminogen activation(GO:0031639)
0.0	0.1	GO:0003099	regulation of the force of heart contraction by chemical signal(GO:0003057) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0	0.7	GO:0001709	cell fate determination(GO:0001709)
0.0	0.8	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	0.2	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.1	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.0	0.2	GO:0023041	neuronal signal transduction(GO:0023041)
0.0	1.3	GO:0045768	obsolete positive regulation of anti-apoptosis(GO:0045768)
0.0	0.2	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0	0.1	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.1	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.9	GO:0006309	DNA catabolic process, endonucleolytic(GO:0000737) apoptotic DNA fragmentation(GO:0006309)
0.0	0.1	GO:0007144	female meiosis I(GO:0007144)
0.0	0.1	GO:0045112	integrin biosynthetic process(GO:0045112)
0.0	0.0	GO:0042905	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0	0.1	GO:0006561	proline biosynthetic process(GO:0006561)
0.0	0.3	GO:0050687	negative regulation of defense response to virus(GO:0050687)
0.0	0.2	GO:0006621	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.7	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.1	GO:0000394	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0	3.6	GO:0007266	Rho protein signal transduction(GO:0007266)
0.0	0.3	GO:0007567	parturition(GO:0007567)
0.0	0.1	GO:0006983	ER overload response(GO:0006983)
0.0	0.1	GO:0048075	positive regulation of eye pigmentation(GO:0048075)
0.0	0.0	GO:0010523	negative regulation of calcium ion transport into cytosol(GO:0010523)
0.0	0.1	GO:0045872	positive regulation of rhodopsin gene expression(GO:0045872)
0.0	0.1	GO:0035246	peptidyl-arginine N-methylation(GO:0035246)
0.0	0.2	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.2	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.0	0.4	GO:0042994	cytoplasmic sequestering of transcription factor(GO:0042994)
0.0	0.1	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.0	0.1	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.3	GO:0048745	smooth muscle tissue development(GO:0048745)
0.0	0.1	GO:0051974	negative regulation of telomerase activity(GO:0051974)
0.0	0.2	GO:0045086	positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0	0.1	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.0	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.1	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.0	0.1	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0	0.2	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.2	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.2	GO:0042572	retinol metabolic process(GO:0042572)
0.0	0.8	GO:0007569	cell aging(GO:0007569)
0.0	0.1	GO:0016126	sterol biosynthetic process(GO:0016126)
0.0	0.1	GO:0015871	choline transport(GO:0015871)
0.0	0.1	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.0	0.1	GO:0006622	protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)
0.0	0.5	GO:0051101	regulation of DNA binding(GO:0051101)
0.0	0.6	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	0.0	GO:0060969	negative regulation of gene silencing(GO:0060969)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.1	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.3	GO:0006783	heme biosynthetic process(GO:0006783)
0.0	0.4	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0	0.0	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.0	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.0	0.1	GO:0043249	erythrocyte maturation(GO:0043249)
0.0	0.4	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.0	0.1	GO:0007549	dosage compensation(GO:0007549)
0.0	0.2	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0	0.1	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.6	GO:0006749	glutathione metabolic process(GO:0006749)
0.0	0.0	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.0	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.1	GO:0043113	receptor clustering(GO:0043113)
0.0	0.1	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.2	GO:0001578	microtubule bundle formation(GO:0001578)
0.0	0.0	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.0	0.1	GO:0032876	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.0	GO:0031635	adenylate cyclase-inhibiting opioid receptor signaling pathway(GO:0031635) opioid receptor signaling pathway(GO:0038003)
0.0	0.1	GO:0046498	S-adenosylhomocysteine metabolic process(GO:0046498)
0.0	0.6	GO:0006958	complement activation, classical pathway(GO:0006958)
0.0	0.0	GO:0060023	soft palate development(GO:0060023)
0.0	0.0	GO:0043276	anoikis(GO:0043276)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	3.5	GO:0070369	beta-catenin-TCF7L2 complex(GO:0070369) beta-catenin-TCF complex(GO:1990907)
0.4	1.1	GO:0031904	endosome lumen(GO:0031904)
0.3	1.0	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.2	3.8	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.1	2.2	GO:0008091	spectrin(GO:0008091)
0.1	1.4	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1	0.4	GO:0033270	paranode region of axon(GO:0033270)
0.1	2.6	GO:0034361	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1	1.1	GO:0005606	laminin-1 complex(GO:0005606)
0.1	0.3	GO:0032144	4-aminobutyrate transaminase complex(GO:0032144)
0.1	0.3	GO:0070288	intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.1	0.3	GO:0042405	nuclear RNA export factor complex(GO:0042272) nuclear inclusion body(GO:0042405)
0.1	0.5	GO:0001739	sex chromatin(GO:0001739)
0.1	0.1	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.1	0.2	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1	1.8	GO:0005796	Golgi lumen(GO:0005796)
0.1	0.5	GO:0042575	DNA polymerase complex(GO:0042575)
0.1	0.6	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.2	GO:0060171	stereocilium membrane(GO:0060171)
0.0	0.2	GO:0005667	transcription factor complex(GO:0005667)
0.0	0.2	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.2	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.1	GO:0005588	collagen type V trimer(GO:0005588)
0.0	0.2	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.3	GO:0005915	zonula adherens(GO:0005915)
0.0	2.6	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.9	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.1	GO:1990752	microtubule plus-end(GO:0035371) microtubule end(GO:1990752)
0.0	0.1	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.2	GO:0000145	exocyst(GO:0000145)
0.0	0.1	GO:0031528	microvillus membrane(GO:0031528)
0.0	1.3	GO:0005581	collagen trimer(GO:0005581)
0.0	0.1	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	0.2	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.0	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.1	GO:0042597	outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0	0.2	GO:0030057	desmosome(GO:0030057)
0.0	0.4	GO:0043073	germ cell nucleus(GO:0043073)
0.0	0.0	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.4	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.1	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.4	GO:0071564	npBAF complex(GO:0071564)
0.0	0.1	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.3	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.6	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	0.6	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.1	GO:0001740	Barr body(GO:0001740)
0.0	1.5	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	1.4	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.2	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.1	GO:0042827	platelet dense granule(GO:0042827)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.5	GO:0005794	Golgi apparatus(GO:0005794)
0.0	0.1	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.0	0.7	GO:0000786	nucleosome(GO:0000786)
0.0	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.7	GO:0005625	obsolete soluble fraction(GO:0005625)
0.0	0.6	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	0.2	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.3	GO:0031594	neuromuscular junction(GO:0031594)
0.0	0.4	GO:0035097	methyltransferase complex(GO:0034708) histone methyltransferase complex(GO:0035097)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	4.1	GO:0060422	peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.5	2.7	GO:0034711	inhibin binding(GO:0034711)
0.3	3.3	GO:0030274	LIM domain binding(GO:0030274)
0.2	1.0	GO:0008420	CTD phosphatase activity(GO:0008420)
0.2	1.9	GO:0070700	BMP receptor binding(GO:0070700)
0.2	0.9	GO:0004657	proline dehydrogenase activity(GO:0004657)
0.2	3.5	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.2	0.7	GO:0004782	sulfinoalanine decarboxylase activity(GO:0004782)
0.2	1.3	GO:0042731	PH domain binding(GO:0042731)
0.2	0.6	GO:0003881	CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.2	0.6	GO:0050692	DBD domain binding(GO:0050692)
0.2	0.9	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.2	1.8	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.2	1.2	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.2	2.4	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.2	1.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.2	0.5	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1	1.3	GO:0034056	estrogen response element binding(GO:0034056)
0.1	0.9	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1	1.0	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.1	0.4	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.1	0.8	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1	0.4	GO:0005534	galactose binding(GO:0005534)
0.1	0.8	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	1.1	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.1	1.4	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1	0.8	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1	0.8	GO:0070087	chromo shadow domain binding(GO:0070087)
0.1	1.1	GO:0017127	cholesterol transporter activity(GO:0017127)
0.1	0.6	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1	0.3	GO:0016524	latrotoxin receptor activity(GO:0016524)
0.1	1.4	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1	0.3	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.1	0.3	GO:0008267	poly-glutamine tract binding(GO:0008267)
0.1	0.3	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1	0.2	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.1	0.2	GO:0015217	purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) ATP:ADP antiporter activity(GO:0005471) ADP transmembrane transporter activity(GO:0015217)
0.1	0.2	GO:0042289	MHC class II protein binding(GO:0042289)
0.1	1.0	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.1	0.4	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.1	0.2	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1	0.7	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.1	0.3	GO:0032145	4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.1	0.3	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.1	0.4	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.1	0.4	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.1	0.3	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.1	0.4	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1	0.4	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.2	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.1	0.2	GO:0005046	KDEL sequence binding(GO:0005046)
0.1	1.2	GO:0070717	poly-purine tract binding(GO:0070717)
0.1	0.1	GO:0050682	AF-2 domain binding(GO:0050682)
0.1	0.3	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1	0.4	GO:0043522	leucine zipper domain binding(GO:0043522)
0.1	0.3	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1	0.3	GO:0048406	nerve growth factor binding(GO:0048406)
0.1	0.6	GO:0034185	apolipoprotein binding(GO:0034185)
0.1	0.3	GO:0003998	acylphosphatase activity(GO:0003998)
0.1	0.3	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.1	2.1	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.3	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.2	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.2	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.1	GO:0010861	thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.6	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.3	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.0	0.4	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.2	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	0.3	GO:0005112	Notch binding(GO:0005112)
0.0	0.3	GO:0030955	potassium ion binding(GO:0030955)
0.0	0.5	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.0	GO:0035198	miRNA binding(GO:0035198)
0.0	0.8	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.0	0.9	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.2	GO:0048185	activin binding(GO:0048185)
0.0	0.1	GO:0043199	sulfate binding(GO:0043199)
0.0	0.0	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.0	GO:0051434	BH3 domain binding(GO:0051434)
0.0	0.7	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.3	GO:0004522	ribonuclease A activity(GO:0004522)
0.0	0.1	GO:0016595	NMDA glutamate receptor activity(GO:0004972) glutamate binding(GO:0016595)
0.0	0.1	GO:0016731	ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.0	0.3	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.3	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.1	GO:0004359	glutaminase activity(GO:0004359)
0.0	0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.4	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.8	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.0	0.1	GO:0004376	glycolipid mannosyltransferase activity(GO:0004376)
0.0	0.1	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.0	0.1	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.7	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	1.8	GO:0004879	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0	0.1	GO:0015433	peptide antigen-transporting ATPase activity(GO:0015433)
0.0	0.2	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.6	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.1	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.4	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0	0.2	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.0	2.7	GO:0005254	chloride channel activity(GO:0005254)
0.0	0.5	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.2	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.1	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.1	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0	2.5	GO:0003704	obsolete specific RNA polymerase II transcription factor activity(GO:0003704)
0.0	2.2	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.5	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.2	GO:0004835	tubulin-tyrosine ligase activity(GO:0004835)
0.0	0.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.2	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	1.4	GO:0030165	PDZ domain binding(GO:0030165)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.6	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.1	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.1	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0	0.1	GO:0004337	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0	0.2	GO:0030172	troponin C binding(GO:0030172)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.7	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.1	GO:0008148	obsolete negative transcription elongation factor activity(GO:0008148)
0.0	0.3	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.1	GO:0000403	four-way junction DNA binding(GO:0000400) Y-form DNA binding(GO:0000403)
0.0	0.1	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	3.2	GO:0003702	obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0	0.2	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.1	GO:0004723	calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0	0.3	GO:0003714	transcription corepressor activity(GO:0003714)
0.0	0.2	GO:0070628	proteasome binding(GO:0070628)
0.0	0.2	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0	0.6	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.0	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.1	GO:0061659	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.3	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.7	GO:0002020	protease binding(GO:0002020)
0.0	1.2	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.2	GO:0005003	ephrin receptor activity(GO:0005003)
0.0	0.2	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.0	0.1	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.1	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.2	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.1	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.0	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.1	GO:0016273	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0	0.7	GO:0010843	obsolete promoter binding(GO:0010843)
0.0	0.4	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism(GO:0015662)
0.0	1.0	GO:0005319	lipid transporter activity(GO:0005319)
0.0	0.2	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.2	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.0	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	0.3	GO:0005518	collagen binding(GO:0005518)
0.0	3.7	GO:0016563	obsolete transcription activator activity(GO:0016563)
0.0	0.1	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	1.1	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.5	GO:0030145	manganese ion binding(GO:0030145)
0.0	0.0	GO:0004988	obsolete mu-opioid receptor activity(GO:0004988)
0.0	0.0	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.0	0.2	GO:0042605	peptide antigen binding(GO:0042605)
0.0	0.6	GO:0004221	obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0	0.2	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.2	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.3	ST_WNT_CA2_CYCLIC_GMP_PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.3	ST_IL_13_PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	1.1	SA_B_CELL_RECEPTOR_COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.6	SA_G1_AND_S_PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.2	ST_STAT3_PATHWAY	STAT3 Pathway
0.0	0.1	SA_G2_AND_M_PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.

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