Motif ID: GUAAACA
Z-value: 0.849
Mature miRNA associated with seed GUAAACA:
| Name | miRBase Accession |
|---|---|
| hsa-miR-30a-5p | MIMAT0000087 |
| hsa-miR-30b-5p | MIMAT0000420 |
| hsa-miR-30c-5p | MIMAT0000244 |
| hsa-miR-30d-5p | MIMAT0000245 |
| hsa-miR-30e-5p | MIMAT0000692 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.2 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
| 0.2 | 0.7 | GO:0070171 | negative regulation of tooth mineralization(GO:0070171) |
| 0.2 | 0.7 | GO:0019695 | choline metabolic process(GO:0019695) |
| 0.2 | 0.7 | GO:0002431 | Fc receptor mediated stimulatory signaling pathway(GO:0002431) regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) |
| 0.2 | 0.8 | GO:0018352 | protein-pyridoxal-5-phosphate linkage(GO:0018352) |
| 0.2 | 0.5 | GO:0008218 | bioluminescence(GO:0008218) |
| 0.2 | 0.7 | GO:0060743 | epithelial cell maturation involved in prostate gland development(GO:0060743) |
| 0.2 | 0.5 | GO:0034139 | regulation of toll-like receptor 3 signaling pathway(GO:0034139) |
| 0.2 | 0.9 | GO:0045722 | response to muscle activity(GO:0014850) positive regulation of gluconeogenesis(GO:0045722) |
| 0.1 | 0.4 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) |
| 0.1 | 0.4 | GO:2000051 | pericardium morphogenesis(GO:0003344) post-embryonic appendage morphogenesis(GO:0035120) mammary placode formation(GO:0060596) negative regulation of non-canonical Wnt signaling pathway(GO:2000051) |
| 0.1 | 0.5 | GO:0048935 | peripheral nervous system neuron development(GO:0048935) |
| 0.1 | 1.2 | GO:0015886 | heme transport(GO:0015886) |
| 0.1 | 0.4 | GO:0007538 | primary sex determination(GO:0007538) |
| 0.1 | 0.4 | GO:0001543 | ovarian follicle rupture(GO:0001543) |
| 0.1 | 0.7 | GO:0010842 | retina layer formation(GO:0010842) camera-type eye photoreceptor cell differentiation(GO:0060219) |
| 0.1 | 0.3 | GO:0042369 | vitamin D catabolic process(GO:0042369) |
| 0.1 | 0.6 | GO:0010832 | negative regulation of myotube differentiation(GO:0010832) |
| 0.1 | 0.5 | GO:0032933 | response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501) |
| 0.1 | 0.9 | GO:0006546 | glycine catabolic process(GO:0006546) |
| 0.1 | 0.6 | GO:0006538 | glutamate catabolic process(GO:0006538) |
| 0.1 | 0.3 | GO:0048642 | negative regulation of skeletal muscle tissue development(GO:0048642) |
| 0.1 | 0.3 | GO:0007109 | obsolete cytokinesis, completion of separation(GO:0007109) protein hexamerization(GO:0034214) |
| 0.1 | 0.2 | GO:0032071 | regulation of endodeoxyribonuclease activity(GO:0032071) |
| 0.1 | 0.4 | GO:0042271 | susceptibility to natural killer cell mediated cytotoxicity(GO:0042271) |
| 0.1 | 0.9 | GO:0010824 | regulation of centrosome duplication(GO:0010824) |
| 0.1 | 0.3 | GO:0042097 | interleukin-4 biosynthetic process(GO:0042097) positive regulation of interleukin-10 biosynthetic process(GO:0045082) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404) |
| 0.1 | 0.5 | GO:0031061 | negative regulation of histone methylation(GO:0031061) |
| 0.1 | 0.5 | GO:0006883 | cellular sodium ion homeostasis(GO:0006883) |
| 0.1 | 0.3 | GO:0001544 | initiation of primordial ovarian follicle growth(GO:0001544) |
| 0.1 | 0.5 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
| 0.1 | 0.2 | GO:0021529 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780) |
| 0.1 | 0.4 | GO:0060017 | parathyroid gland development(GO:0060017) |
| 0.1 | 0.8 | GO:0060123 | regulation of growth hormone secretion(GO:0060123) |
| 0.1 | 0.3 | GO:0031580 | membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) |
| 0.1 | 0.3 | GO:0032525 | somite rostral/caudal axis specification(GO:0032525) |
| 0.1 | 0.2 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) |
| 0.1 | 0.2 | GO:0071539 | Golgi localization(GO:0051645) protein localization to centrosome(GO:0071539) |
| 0.1 | 0.4 | GO:0042518 | negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518) |
| 0.1 | 0.2 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.1 | 0.2 | GO:0032328 | alanine transport(GO:0032328) |
| 0.1 | 0.2 | GO:0051066 | dihydrobiopterin metabolic process(GO:0051066) |
| 0.1 | 0.2 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
| 0.1 | 0.1 | GO:0060729 | intestinal epithelial structure maintenance(GO:0060729) |
| 0.0 | 0.2 | GO:0051409 | response to nitrosative stress(GO:0051409) |
| 0.0 | 0.2 | GO:0046671 | regulation of nitrogen utilization(GO:0006808) positive regulation of neuron maturation(GO:0014042) nitrogen utilization(GO:0019740) cochlear nucleus development(GO:0021747) negative regulation of cellular pH reduction(GO:0032848) glial cell apoptotic process(GO:0034349) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671) positive regulation of cell maturation(GO:1903431) |
| 0.0 | 0.2 | GO:0008298 | intracellular mRNA localization(GO:0008298) |
| 0.0 | 0.1 | GO:0034625 | fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.0 | 0.1 | GO:0006740 | glyoxylate cycle(GO:0006097) NADPH regeneration(GO:0006740) |
| 0.0 | 0.7 | GO:0071044 | histone mRNA catabolic process(GO:0071044) |
| 0.0 | 0.2 | GO:0060029 | convergent extension involved in organogenesis(GO:0060029) |
| 0.0 | 0.1 | GO:0021896 | forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897) |
| 0.0 | 0.2 | GO:0032776 | DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116) |
| 0.0 | 0.1 | GO:0048075 | regulation of eye pigmentation(GO:0048073) positive regulation of eye pigmentation(GO:0048075) |
| 0.0 | 0.2 | GO:0006930 | substrate-dependent cell migration, cell extension(GO:0006930) |
| 0.0 | 0.6 | GO:0032411 | positive regulation of transporter activity(GO:0032411) |
| 0.0 | 0.2 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
| 0.0 | 0.3 | GO:0048625 | myoblast fate commitment(GO:0048625) |
| 0.0 | 0.1 | GO:0032355 | response to estradiol(GO:0032355) |
| 0.0 | 0.4 | GO:0046339 | diacylglycerol metabolic process(GO:0046339) |
| 0.0 | 1.1 | GO:0048009 | insulin-like growth factor receptor signaling pathway(GO:0048009) |
| 0.0 | 0.1 | GO:0003099 | positive regulation of the force of heart contraction by chemical signal(GO:0003099) |
| 0.0 | 0.3 | GO:0016998 | cell wall macromolecule catabolic process(GO:0016998) |
| 0.0 | 0.1 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
| 0.0 | 0.1 | GO:0071364 | cellular response to epidermal growth factor stimulus(GO:0071364) |
| 0.0 | 0.1 | GO:0007206 | phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) |
| 0.0 | 0.2 | GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552) |
| 0.0 | 0.2 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
| 0.0 | 0.3 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.0 | 0.4 | GO:0042535 | positive regulation of tumor necrosis factor biosynthetic process(GO:0042535) |
| 0.0 | 0.1 | GO:0070384 | Harderian gland development(GO:0070384) |
| 0.0 | 0.6 | GO:0030199 | collagen fibril organization(GO:0030199) |
| 0.0 | 0.2 | GO:0045663 | positive regulation of myoblast differentiation(GO:0045663) |
| 0.0 | 0.5 | GO:0006386 | transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386) |
| 0.0 | 0.1 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
| 0.0 | 0.1 | GO:0072383 | plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) |
| 0.0 | 0.2 | GO:0007185 | transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185) |
| 0.0 | 0.2 | GO:0071353 | cellular response to interleukin-4(GO:0071353) |
| 0.0 | 0.1 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.0 | 0.1 | GO:0072106 | regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107) |
| 0.0 | 0.2 | GO:0060487 | lung epithelial cell differentiation(GO:0060487) |
| 0.0 | 0.7 | GO:0019835 | cytolysis(GO:0019835) |
| 0.0 | 0.2 | GO:0006622 | protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666) |
| 0.0 | 0.2 | GO:0035058 | nonmotile primary cilium assembly(GO:0035058) |
| 0.0 | 0.1 | GO:0046642 | negative regulation of alpha-beta T cell proliferation(GO:0046642) |
| 0.0 | 0.1 | GO:0071679 | cell proliferation in midbrain(GO:0033278) commissural neuron axon guidance(GO:0071679) |
| 0.0 | 0.1 | GO:0019255 | glucose 1-phosphate metabolic process(GO:0019255) |
| 0.0 | 0.2 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.0 | 0.4 | GO:0016578 | histone deubiquitination(GO:0016578) |
| 0.0 | 0.1 | GO:0021937 | cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937) |
| 0.0 | 0.1 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.0 | 0.1 | GO:0015917 | aminophospholipid transport(GO:0015917) |
| 0.0 | 0.2 | GO:0006600 | creatine metabolic process(GO:0006600) |
| 0.0 | 0.1 | GO:0009202 | deoxyribonucleoside triphosphate biosynthetic process(GO:0009202) |
| 0.0 | 0.1 | GO:0060325 | face morphogenesis(GO:0060325) |
| 0.0 | 0.2 | GO:0042036 | negative regulation of cytokine biosynthetic process(GO:0042036) |
| 0.0 | 0.1 | GO:0045046 | protein import into peroxisome membrane(GO:0045046) |
| 0.0 | 0.1 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.0 | 0.2 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.0 | 0.2 | GO:0006027 | glycosaminoglycan catabolic process(GO:0006027) |
| 0.0 | 0.2 | GO:0032608 | interferon-beta production(GO:0032608) regulation of interferon-beta production(GO:0032648) |
| 0.0 | 0.1 | GO:0032957 | inositol trisphosphate metabolic process(GO:0032957) |
| 0.0 | 0.1 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 0.0 | 0.1 | GO:0048251 | elastic fiber assembly(GO:0048251) extracellular matrix assembly(GO:0085029) |
| 0.0 | 0.2 | GO:0046718 | viral entry into host cell(GO:0046718) |
| 0.0 | 0.0 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
| 0.0 | 0.1 | GO:0017157 | regulation of exocytosis(GO:0017157) |
| 0.0 | 0.2 | GO:0045648 | positive regulation of erythrocyte differentiation(GO:0045648) |
| 0.0 | 0.1 | GO:0007422 | peripheral nervous system development(GO:0007422) |
| 0.0 | 0.1 | GO:0050847 | progesterone receptor signaling pathway(GO:0050847) |
| 0.0 | 0.2 | GO:0001893 | maternal placenta development(GO:0001893) |
| 0.0 | 0.2 | GO:0007020 | microtubule nucleation(GO:0007020) |
| 0.0 | 0.2 | GO:0032876 | regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023) |
| 0.0 | 0.5 | GO:0030641 | regulation of cellular pH(GO:0030641) |
| 0.0 | 0.3 | GO:0002076 | osteoblast development(GO:0002076) |
| 0.0 | 0.1 | GO:0010225 | response to UV-C(GO:0010225) |
| 0.0 | 0.0 | GO:0072076 | nephrogenic mesenchyme development(GO:0072076) nephrogenic mesenchyme morphogenesis(GO:0072134) kidney mesenchymal cell proliferation(GO:0072135) metanephric mesenchymal cell proliferation involved in metanephros development(GO:0072136) |
| 0.0 | 0.2 | GO:0032400 | melanosome localization(GO:0032400) |
| 0.0 | 0.2 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
| 0.0 | 1.0 | GO:0007588 | excretion(GO:0007588) |
| 0.0 | 0.1 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.0 | 0.2 | GO:0006596 | polyamine biosynthetic process(GO:0006596) |
| 0.0 | 0.2 | GO:0031000 | response to caffeine(GO:0031000) |
| 0.0 | 0.5 | GO:0090090 | negative regulation of canonical Wnt signaling pathway(GO:0090090) |
| 0.0 | 0.7 | GO:0009791 | post-embryonic development(GO:0009791) |
| 0.0 | 0.4 | GO:0006024 | glycosaminoglycan biosynthetic process(GO:0006024) |
| 0.0 | 0.2 | GO:0050812 | acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812) |
| 0.0 | 0.1 | GO:0051926 | negative regulation of calcium ion transport(GO:0051926) |
| 0.0 | 0.1 | GO:0001782 | B cell homeostasis(GO:0001782) |
| 0.0 | 0.4 | GO:0050868 | negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038) |
| 0.0 | 0.1 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
| 0.0 | 0.1 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.2 | GO:0030895 | apolipoprotein B mRNA editing enzyme complex(GO:0030895) |
| 0.4 | 0.4 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.2 | 0.8 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.2 | 0.8 | GO:0005594 | collagen type IX trimer(GO:0005594) |
| 0.1 | 0.5 | GO:0042405 | nuclear RNA export factor complex(GO:0042272) nuclear inclusion body(GO:0042405) |
| 0.1 | 0.3 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.1 | 1.1 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.1 | 0.3 | GO:0000306 | extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313) |
| 0.1 | 0.5 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.1 | 0.6 | GO:0016442 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
| 0.0 | 0.2 | GO:0070695 | FHF complex(GO:0070695) |
| 0.0 | 0.2 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.0 | 1.2 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.0 | 0.3 | GO:0000300 | obsolete peripheral to membrane of membrane fraction(GO:0000300) |
| 0.0 | 0.1 | GO:0031213 | RSF complex(GO:0031213) |
| 0.0 | 0.9 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.0 | 0.2 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.0 | 0.1 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.0 | 0.1 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 0.7 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.0 | 0.2 | GO:0030897 | HOPS complex(GO:0030897) |
| 0.0 | 0.4 | GO:0000808 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 0.0 | 0.1 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.0 | 0.1 | GO:0033268 | node of Ranvier(GO:0033268) |
| 0.0 | 0.1 | GO:0016939 | kinesin II complex(GO:0016939) |
| 0.0 | 0.2 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.0 | 1.5 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.0 | 1.2 | GO:0005884 | actin filament(GO:0005884) |
| 0.0 | 0.4 | GO:0043034 | costamere(GO:0043034) |
| 0.0 | 0.3 | GO:0030914 | STAGA complex(GO:0030914) |
| 0.0 | 0.2 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 0.1 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 0.2 | GO:0030061 | mitochondrial crista(GO:0030061) |
| 0.0 | 0.2 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.0 | 0.1 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.0 | 0.1 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.0 | 0.1 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.0 | 0.1 | GO:0042584 | chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584) |
| 0.0 | 0.1 | GO:0042827 | platelet dense granule(GO:0042827) |
| 0.0 | 0.4 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.0 | 0.9 | GO:0031902 | late endosome membrane(GO:0031902) |
| 0.0 | 0.1 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.0 | 0.7 | GO:0031970 | mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970) |
| 0.0 | 0.1 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.0 | 0.1 | GO:0000791 | euchromatin(GO:0000791) |
| 0.0 | 0.2 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 0.3 | GO:0016514 | SWI/SNF complex(GO:0016514) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.6 | GO:0005010 | insulin-like growth factor-activated receptor activity(GO:0005010) |
| 0.2 | 0.5 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
| 0.2 | 0.7 | GO:0033265 | choline binding(GO:0033265) |
| 0.1 | 1.2 | GO:0015232 | heme transporter activity(GO:0015232) |
| 0.1 | 0.8 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
| 0.1 | 0.4 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 0.1 | 0.4 | GO:0004723 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) |
| 0.1 | 1.3 | GO:0016638 | oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638) |
| 0.1 | 0.3 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.1 | 0.3 | GO:0070576 | vitamin D 24-hydroxylase activity(GO:0070576) |
| 0.1 | 0.5 | GO:0008158 | hedgehog receptor activity(GO:0008158) |
| 0.1 | 0.3 | GO:0003951 | NAD+ kinase activity(GO:0003951) |
| 0.1 | 1.1 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.1 | 0.2 | GO:0042285 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
| 0.1 | 1.0 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.1 | 0.4 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
| 0.1 | 0.8 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.0 | 0.5 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 0.0 | 0.3 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.0 | 0.2 | GO:0043398 | HLH domain binding(GO:0043398) |
| 0.0 | 0.1 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
| 0.0 | 0.4 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) |
| 0.0 | 0.4 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.0 | 0.2 | GO:0046404 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) |
| 0.0 | 0.1 | GO:0008489 | UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489) |
| 0.0 | 0.1 | GO:0004450 | isocitrate dehydrogenase (NADP+) activity(GO:0004450) |
| 0.0 | 0.7 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.0 | 0.3 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.0 | 0.4 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.0 | 0.2 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.0 | 0.2 | GO:0019871 | sodium channel inhibitor activity(GO:0019871) |
| 0.0 | 0.2 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.0 | 0.1 | GO:0051765 | obsolete inositol-1,3,4-trisphosphate 5/6-kinase activity(GO:0035300) inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765) |
| 0.0 | 0.4 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.0 | 0.2 | GO:0030955 | potassium ion binding(GO:0030955) |
| 0.0 | 0.4 | GO:0016634 | oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634) |
| 0.0 | 0.4 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 0.0 | 0.1 | GO:0008545 | JUN kinase kinase activity(GO:0008545) |
| 0.0 | 0.2 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
| 0.0 | 0.6 | GO:0016896 | exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896) |
| 0.0 | 0.2 | GO:0004741 | magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
| 0.0 | 0.1 | GO:0019962 | type I interferon binding(GO:0019962) |
| 0.0 | 1.4 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
| 0.0 | 0.2 | GO:0042978 | ornithine decarboxylase inhibitor activity(GO:0008073) ornithine decarboxylase activator activity(GO:0042978) |
| 0.0 | 0.4 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970) |
| 0.0 | 0.2 | GO:0000827 | inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) |
| 0.0 | 0.3 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.0 | 0.5 | GO:0032452 | histone demethylase activity(GO:0032452) |
| 0.0 | 0.1 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
| 0.0 | 0.7 | GO:0001228 | transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 0.0 | 0.3 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.0 | 0.5 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
| 0.0 | 0.4 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
| 0.0 | 0.1 | GO:0015247 | aminophospholipid transporter activity(GO:0015247) |
| 0.0 | 0.2 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
| 0.0 | 0.2 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.0 | 0.1 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939) |
| 0.0 | 0.1 | GO:0004939 | beta-adrenergic receptor activity(GO:0004939) |
| 0.0 | 0.1 | GO:0019789 | SUMO transferase activity(GO:0019789) |
| 0.0 | 0.2 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.0 | 0.2 | GO:0016944 | obsolete RNA polymerase II transcription elongation factor activity(GO:0016944) |
| 0.0 | 0.9 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.0 | 0.1 | GO:0009922 | fatty acid elongase activity(GO:0009922) |
| 0.0 | 0.4 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) |
| 0.0 | 0.3 | GO:0016986 | obsolete transcription initiation factor activity(GO:0016986) |
| 0.0 | 0.2 | GO:0016595 | glutamate binding(GO:0016595) |
| 0.0 | 0.1 | GO:0034416 | bisphosphoglycerate phosphatase activity(GO:0034416) |
| 0.0 | 0.2 | GO:0015166 | polyol transmembrane transporter activity(GO:0015166) |
| 0.0 | 0.2 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
| 0.0 | 0.2 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 0.0 | 0.1 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
| 0.0 | 0.1 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
| 0.0 | 0.1 | GO:0004910 | interleukin-1, Type II, blocking receptor activity(GO:0004910) |
| 0.0 | 0.2 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
| 0.0 | 0.1 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390) |
| 0.0 | 0.1 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.0 | 0.2 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.0 | 0.2 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.0 | 0.8 | GO:0042826 | histone deacetylase binding(GO:0042826) |
| 0.0 | 0.1 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
| 0.0 | 0.3 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.0 | 0.4 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 0.0 | GO:0016563 | obsolete transcription activator activity(GO:0016563) |
| 0.0 | 0.3 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.0 | 0.1 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 0.0 | 0.2 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.0 | 0.1 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.0 | 0.1 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.0 | 0.1 | GO:0050682 | AF-2 domain binding(GO:0050682) |
| 0.0 | 0.0 | GO:0004948 | calcitonin receptor activity(GO:0004948) |
| 0.0 | 0.2 | GO:0016303 | 1-phosphatidylinositol-3-kinase activity(GO:0016303) |
| 0.0 | 0.2 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.0 | 0.4 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.0 | 0.1 | GO:0031685 | adenosine receptor binding(GO:0031685) |
| 0.0 | 0.6 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062) |
| 0.0 | 0.2 | GO:0015929 | hexosaminidase activity(GO:0015929) |
| 0.0 | 0.2 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.0 | 0.1 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 0.0 | 0.2 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.0 | 0.1 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.4 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 0.0 | 1.0 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.0 | 1.0 | SA_B_CELL_RECEPTOR_COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.0 | 0.1 | SA_TRKA_RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
| 0.0 | 0.4 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.0 | 0.6 | ST_GA13_PATHWAY | G alpha 13 Pathway |
