Motif ID: GZF1

Z-value: 1.111


Transcription factors associated with GZF1:

Gene SymbolEntrez IDGene Name
GZF1 ENSG00000125812.11 GZF1



Activity profile for motif GZF1.

activity profile for motif GZF1


Sorted Z-values histogram for motif GZF1

Sorted Z-values for motif GZF1



Network of associatons between targets according to the STRING database.



First level regulatory network of GZF1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_52535712 3.117 ENST00000216286.5
ENST00000541773.1
 NID2

nidogen 2 (osteonidogen)

chr3_-_87040233 2.121 ENST00000398399.2
 VGLL3
vestigial like 3 (Drosophila)
chr3_-_114035026 1.784 ENST00000570269.1
 RP11-553L6.5
RP11-553L6.5
chr18_-_53303123 1.676 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
 TCF4


transcription factor 4


chr1_+_26606608 1.191 ENST00000319041.6
 SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr1_-_144995002 1.076 ENST00000369356.4
 PDE4DIP
phosphodiesterase 4D interacting protein
chrX_+_54835493 1.017 ENST00000396224.1
 MAGED2
melanoma antigen family D, 2
chr1_-_144994909 0.845 ENST00000369347.4
ENST00000369354.3
 PDE4DIP

phosphodiesterase 4D interacting protein

chr1_-_144995074 0.831 ENST00000534536.1
 PDE4DIP
phosphodiesterase 4D interacting protein
chr14_-_92413353 0.782 ENST00000556154.1
 FBLN5
fibulin 5
chr10_-_126849588 0.764 ENST00000411419.2
 CTBP2
C-terminal binding protein 2
chr10_-_126849068 0.751 ENST00000494626.2
ENST00000337195.5
 CTBP2

C-terminal binding protein 2

chr14_-_92413727 0.701 ENST00000267620.10
 FBLN5
fibulin 5
chr3_+_30647994 0.691 ENST00000295754.5
 TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr5_+_92919043 0.583 ENST00000327111.3
 NR2F1
nuclear receptor subfamily 2, group F, member 1
chr3_+_30648066 0.565 ENST00000359013.4
 TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr14_+_101292445 0.531 ENST00000429159.2
ENST00000520714.1
ENST00000522771.2
ENST00000424076.3
ENST00000423456.1
ENST00000521404.1
ENST00000556736.1
ENST00000451743.2
ENST00000398518.2
ENST00000554639.1
ENST00000452120.2
ENST00000519709.1
ENST00000412736.2
 MEG3












maternally expressed 3 (non-protein coding)












chr20_+_42086525 0.444 ENST00000244020.3
 SRSF6
serine/arginine-rich splicing factor 6
chr9_+_96338647 0.409 ENST00000359246.4
 PHF2
PHD finger protein 2
chr1_-_144994840 0.408 ENST00000369351.3
ENST00000369349.3
 PDE4DIP

phosphodiesterase 4D interacting protein

chr1_-_226374373 0.392 ENST00000366812.5
 ACBD3
acyl-CoA binding domain containing 3
chr7_-_27183263 0.328 ENST00000222726.3
 HOXA5
homeobox A5
chrX_+_102883620 0.319 ENST00000372626.3
 TCEAL1
transcription elongation factor A (SII)-like 1
chr12_+_107168418 0.304 ENST00000392839.2
ENST00000548914.1
ENST00000355478.2
ENST00000552619.1
ENST00000549643.1
 RIC8B




RIC8 guanine nucleotide exchange factor B




chr1_-_32801825 0.275 ENST00000329421.7
 MARCKSL1
MARCKS-like 1
chr9_+_96338860 0.233 ENST00000375376.4
 PHF2
PHD finger protein 2
chr12_+_104458235 0.230 ENST00000229330.4
 HCFC2
host cell factor C2
chr9_-_14308004 0.212 ENST00000493697.1
 NFIB
nuclear factor I/B
chr9_+_131133598 0.160 ENST00000372853.4
ENST00000452446.1
ENST00000372850.1
ENST00000372847.1
 URM1



ubiquitin related modifier 1



chr12_-_76478417 0.129 ENST00000552342.1
 NAP1L1
nucleosome assembly protein 1-like 1
chr12_-_76478386 0.125 ENST00000535020.2
 NAP1L1
nucleosome assembly protein 1-like 1
chr14_-_21979428 0.109 ENST00000538267.1
ENST00000298717.4
 METTL3

methyltransferase like 3

chr10_+_89264625 0.099 ENST00000371996.4
ENST00000371994.4
 MINPP1

multiple inositol-polyphosphate phosphatase 1

chr2_-_150444300 0.094 ENST00000303319.5
 MMADHC
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr12_-_76478446 0.081 ENST00000393263.3
ENST00000548044.1
ENST00000547704.1
ENST00000431879.3
ENST00000549596.1
ENST00000550934.1
ENST00000551600.1
ENST00000547479.1
ENST00000547773.1
ENST00000544816.1
ENST00000542344.1
ENST00000548273.1
 NAP1L1











nucleosome assembly protein 1-like 1











chr14_+_22293618 0.071 ENST00000390432.2
 TRAV10
T cell receptor alpha variable 10
chr2_-_150444116 0.069 ENST00000428879.1
ENST00000422782.2
 MMADHC

methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria

chr7_+_102004322 0.055 ENST00000496391.1
 PRKRIP1
PRKR interacting protein 1 (IL11 inducible)
chr7_-_105029812 0.045 ENST00000482897.1
 SRPK2
SRSF protein kinase 2
chr6_+_30524663 0.019 ENST00000376560.3
 PRR3
proline rich 3
chr6_+_30525051 0.007 ENST00000376557.3
 PRR3
proline rich 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0008218 bioluminescence(GO:0008218)
0.5 1.5 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
0.4 1.3 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.2 0.6 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 0.5 GO:0034337 RNA folding(GO:0034337) DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) regulation of DNA methylation(GO:0044030)
0.1 0.3 GO:0060574 trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536) intestinal epithelial cell maturation(GO:0060574) intestinal epithelial cell development(GO:0060576)
0.1 1.5 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.2 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 1.7 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.2 GO:0006400 tRNA modification(GO:0006400)
0.0 0.1 GO:0001510 RNA methylation(GO:0001510)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0071953 elastic fiber(GO:0071953)
0.2 1.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 3.1 GO:0005604 basement membrane(GO:0005604)
0.0 0.3 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 1.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 3.2 GO:0030016 myofibril(GO:0030016)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 1.7 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093)
0.1 3.1 GO:0005518 collagen binding(GO:0005518)
0.1 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.6 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 1.2 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.5 GO:0051287 NAD binding(GO:0051287)
0.0 0.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 1.5 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)