Motif ID: HAND1
Z-value: 1.315
Transcription factors associated with HAND1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| HAND1 | ENSG00000113196.2 | HAND1 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 5.2 | GO:0009609 | response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609) |
| 0.5 | 4.3 | GO:0034392 | negative regulation of smooth muscle cell apoptotic process(GO:0034392) |
| 0.4 | 8.8 | GO:0051923 | purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) sulfation(GO:0051923) |
| 0.2 | 1.0 | GO:0006562 | proline catabolic process(GO:0006562) |
| 0.2 | 2.5 | GO:0006750 | glutathione biosynthetic process(GO:0006750) |
| 0.1 | 8.1 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.1 | 0.6 | GO:0035455 | response to interferon-alpha(GO:0035455) |
| 0.1 | 0.4 | GO:2000858 | renin-angiotensin regulation of aldosterone production(GO:0002018) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) positive regulation of NAD(P)H oxidase activity(GO:0033864) mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) regulation of mineralocorticoid secretion(GO:2000855) regulation of aldosterone secretion(GO:2000858) |
| 0.1 | 0.3 | GO:0030037 | actin filament reorganization involved in cell cycle(GO:0030037) actin filament reorganization(GO:0090527) |
| 0.1 | 1.1 | GO:0050687 | negative regulation of defense response to virus(GO:0050687) |
| 0.1 | 0.2 | GO:0035461 | vitamin transmembrane transport(GO:0035461) |
| 0.1 | 0.3 | GO:0045589 | regulation of regulatory T cell differentiation(GO:0045589) |
| 0.1 | 0.4 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
| 0.0 | 0.2 | GO:0043045 | DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538) |
| 0.0 | 0.2 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
| 0.0 | 3.3 | GO:0042742 | defense response to bacterium(GO:0042742) |
| 0.0 | 0.1 | GO:0051971 | positive regulation of transmission of nerve impulse(GO:0051971) |
| 0.0 | 1.0 | GO:0006959 | humoral immune response(GO:0006959) |
| 0.0 | 0.1 | GO:0070170 | regulation of tooth mineralization(GO:0070170) |
| 0.0 | 2.1 | GO:0048511 | rhythmic process(GO:0048511) |
| 0.0 | 0.2 | GO:0030317 | sperm motility(GO:0030317) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 4.3 | GO:0042627 | chylomicron(GO:0042627) |
| 0.1 | 1.3 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
| 0.1 | 0.8 | GO:0030061 | mitochondrial crista(GO:0030061) |
| 0.0 | 0.2 | GO:0000791 | euchromatin(GO:0000791) |
| 0.0 | 0.3 | GO:0030914 | STAGA complex(GO:0030914) |
| 0.0 | 0.3 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 8.8 | GO:0047894 | flavonol 3-sulfotransferase activity(GO:0047894) |
| 0.9 | 4.3 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
| 0.3 | 5.2 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 0.2 | 1.0 | GO:0004657 | proline dehydrogenase activity(GO:0004657) |
| 0.2 | 0.6 | GO:0019962 | type I interferon binding(GO:0019962) |
| 0.2 | 2.5 | GO:0003840 | gamma-glutamyltransferase activity(GO:0003840) |
| 0.1 | 0.4 | GO:0001596 | angiotensin type I receptor activity(GO:0001596) |
| 0.1 | 3.5 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.0 | 1.3 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.0 | 0.2 | GO:0090482 | vitamin transmembrane transporter activity(GO:0090482) |
| 0.0 | 0.2 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.0 | 0.5 | GO:0005537 | mannose binding(GO:0005537) |
| 0.0 | 0.6 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.0 | 0.5 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.0 | 0.1 | GO:0004090 | carbonyl reductase (NADPH) activity(GO:0004090) |
| 0.0 | 0.1 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
| 0.0 | 0.1 | GO:0004461 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) lactose synthase activity(GO:0004461) |
| 0.0 | 0.3 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.0 | 1.3 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.0 | 0.3 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.0 | 0.2 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.3 | SA_FAS_SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
