Motif ID: HES1

Z-value: 1.839


Transcription factors associated with HES1:

Gene SymbolEntrez IDGene Name
HES1 ENSG00000114315.3 HES1



Activity profile for motif HES1.

activity profile for motif HES1


Sorted Z-values histogram for motif HES1

Sorted Z-values for motif HES1



Network of associatons between targets according to the STRING database.



First level regulatory network of HES1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_7023491 2.689 ENST00000541477.1
ENST00000229277.1
ENO2

enolase 2 (gamma, neuronal)

chr22_+_22930626 1.937 ENST00000390302.2
IGLV2-33
immunoglobulin lambda variable 2-33 (non-functional)
chr1_-_25291475 1.921 ENST00000338888.3
ENST00000399916.1
RUNX3

runt-related transcription factor 3

chr15_+_89182178 1.703 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr2_-_73511559 1.683 ENST00000521871.1
FBXO41
F-box protein 41
chr2_-_96811170 1.675 ENST00000288943.4
DUSP2
dual specificity phosphatase 2
chr20_-_3154162 1.673 ENST00000360342.3
LZTS3
Homo sapiens leucine zipper, putative tumor suppressor family member 3 (LZTS3), mRNA.
chr15_+_89181974 1.629 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr15_+_89182156 1.595 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr12_+_7023735 1.591 ENST00000538763.1
ENST00000544774.1
ENST00000545045.2
ENO2


enolase 2 (gamma, neuronal)


chr1_-_111743285 1.503 ENST00000357640.4
DENND2D
DENN/MADD domain containing 2D
chr21_+_35445827 1.430 ENST00000381151.3
ENST00000608209.1
SLC5A3
SLC5A3
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
sodium/myo-inositol cotransporter
chr1_-_46152174 1.402 ENST00000290795.3
ENST00000355105.3
GPBP1L1

GC-rich promoter binding protein 1-like 1

chr12_-_117537240 1.396 ENST00000392545.4
ENST00000541210.1
ENST00000335209.7
TESC


tescalcin


chrX_-_131623982 1.349 ENST00000370844.1
MBNL3
muscleblind-like splicing regulator 3
chr7_+_150065278 1.337 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
REPIN1


replication initiator 1


chr17_-_42402138 1.308 ENST00000592857.1
ENST00000586016.1
ENST00000590194.1
ENST00000377095.5
ENST00000588049.1
ENST00000586633.1
ENST00000537904.2
ENST00000585636.1
ENST00000585523.1
ENST00000225308.8
SLC25A39









solute carrier family 25, member 39









chr3_+_121554046 1.305 ENST00000273668.2
ENST00000451944.2
EAF2

ELL associated factor 2

chr10_-_95360983 1.292 ENST00000371464.3
RBP4
retinol binding protein 4, plasma
chr5_+_156693091 1.290 ENST00000318218.6
ENST00000442283.2
ENST00000522463.1
ENST00000521420.1
CYFIP2



cytoplasmic FMR1 interacting protein 2



chr3_-_47823298 1.277 ENST00000254480.5
SMARCC1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr20_-_43280325 1.244 ENST00000537820.1
ADA
adenosine deaminase
chr20_+_35201857 1.200 ENST00000373874.2
TGIF2
TGFB-induced factor homeobox 2
chr15_+_41056218 1.192 ENST00000260447.4
GCHFR
GTP cyclohydrolase I feedback regulator
chr19_-_1652575 1.181 ENST00000587235.1
ENST00000262965.5
TCF3

transcription factor 3

chr5_+_156693159 1.138 ENST00000347377.6
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr17_-_10101868 1.110 ENST00000432992.2
ENST00000540214.1
GAS7

growth arrest-specific 7

chr20_+_35201993 1.039 ENST00000373872.4
TGIF2
TGFB-induced factor homeobox 2
chr13_-_41635512 1.037 ENST00000405737.2
ELF1
E74-like factor 1 (ets domain transcription factor)
chr3_+_184081137 1.019 ENST00000443489.1
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chrX_-_131623874 1.017 ENST00000436215.1
MBNL3
muscleblind-like splicing regulator 3
chr19_+_34855874 0.976 ENST00000588991.2
GPI
glucose-6-phosphate isomerase
chr20_+_55966444 0.964 ENST00000356208.5
ENST00000440234.2
RBM38

RNA binding motif protein 38

chr7_+_99775366 0.956 ENST00000394018.2
ENST00000416412.1
STAG3

stromal antigen 3

chr1_+_227127981 0.949 ENST00000366778.1
ENST00000366777.3
ENST00000458507.2
ADCK3


aarF domain containing kinase 3


chr20_+_61273797 0.944 ENST00000217159.1
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr16_-_88717423 0.940 ENST00000568278.1
ENST00000569359.1
ENST00000567174.1
CYBA


cytochrome b-245, alpha polypeptide


chr3_+_184081175 0.939 ENST00000452961.1
ENST00000296223.3
POLR2H

polymerase (RNA) II (DNA directed) polypeptide H

chr19_+_34856141 0.923 ENST00000586425.1
GPI
glucose-6-phosphate isomerase
chr3_+_184081213 0.921 ENST00000429568.1
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr1_+_28844778 0.919 ENST00000411533.1
RCC1
regulator of chromosome condensation 1
chr19_+_30302805 0.919 ENST00000262643.3
ENST00000575243.1
ENST00000357943.5
CCNE1


cyclin E1


chr12_-_125348329 0.912 ENST00000546215.1
ENST00000415380.2
ENST00000261693.6
ENST00000376788.1
ENST00000545493.1
SCARB1




scavenger receptor class B, member 1




chr2_+_204193129 0.909 ENST00000417864.1
ABI2
abl-interactor 2
chr17_-_3867585 0.907 ENST00000359983.3
ENST00000352011.3
ENST00000397043.3
ENST00000397041.3
ENST00000397035.3
ENST00000397039.1
ENST00000309890.7
ATP2A3






ATPase, Ca++ transporting, ubiquitous






chr19_+_34855925 0.896 ENST00000590375.1
ENST00000356487.5
GPI

glucose-6-phosphate isomerase

chr15_+_74908147 0.887 ENST00000568139.1
ENST00000563297.1
ENST00000568488.1
ENST00000352989.5
ENST00000348245.3
CLK3




CDC-like kinase 3




chr16_+_85646891 0.874 ENST00000393243.1
GSE1
Gse1 coiled-coil protein
chr6_+_42749759 0.872 ENST00000314073.5
GLTSCR1L
GLTSCR1-like
chr14_+_101193246 0.869 ENST00000331224.6
DLK1
delta-like 1 homolog (Drosophila)
chr14_+_101193164 0.865 ENST00000341267.4
DLK1
delta-like 1 homolog (Drosophila)
chr8_-_28243934 0.849 ENST00000521185.1
ENST00000520290.1
ENST00000344423.5
ZNF395


zinc finger protein 395


chr2_+_204192942 0.847 ENST00000295851.5
ENST00000261017.5
ABI2

abl-interactor 2

chr12_-_125348448 0.845 ENST00000339570.5
SCARB1
scavenger receptor class B, member 1
chr8_+_56014949 0.837 ENST00000327381.6
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr14_-_89883412 0.833 ENST00000557258.1
FOXN3
forkhead box N3
chr16_+_85646763 0.833 ENST00000411612.1
ENST00000253458.7
GSE1

Gse1 coiled-coil protein

chr18_+_2655692 0.831 ENST00000320876.6
SMCHD1
structural maintenance of chromosomes flexible hinge domain containing 1
chr4_+_57774042 0.825 ENST00000309042.7
REST
RE1-silencing transcription factor
chr3_-_13009168 0.824 ENST00000273221.4
IQSEC1
IQ motif and Sec7 domain 1
chr17_-_3599696 0.815 ENST00000225328.5
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr8_-_101348408 0.798 ENST00000519527.1
ENST00000522369.1
RNF19A

ring finger protein 19A, RBR E3 ubiquitin protein ligase

chrX_+_152907913 0.792 ENST00000370167.4
DUSP9
dual specificity phosphatase 9
chr11_-_60719213 0.771 ENST00000227880.3
SLC15A3
solute carrier family 15 (oligopeptide transporter), member 3
chr1_+_111682827 0.752 ENST00000357172.4
CEPT1
choline/ethanolamine phosphotransferase 1
chr1_-_32801825 0.752 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr3_+_38495333 0.751 ENST00000352511.4
ACVR2B
activin A receptor, type IIB
chr7_+_150065879 0.740 ENST00000478789.1
ENST00000397281.2
ENST00000444957.1
ENST00000466559.1
ENST00000489432.2
ENST00000475514.1
ENST00000482680.1
ENST00000488943.1
ENST00000518514.1
ZNF775
REPIN1







zinc finger protein 775
replication initiator 1







chr17_-_3599327 0.720 ENST00000551178.1
ENST00000552276.1
ENST00000547178.1
P2RX5


purinergic receptor P2X, ligand-gated ion channel, 5


chr21_+_45285050 0.716 ENST00000291572.8
AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr2_+_170590321 0.712 ENST00000392647.2
KLHL23
kelch-like family member 23
chr20_+_49411523 0.706 ENST00000371608.2
BCAS4
breast carcinoma amplified sequence 4
chr19_+_50887585 0.696 ENST00000440232.2
ENST00000601098.1
ENST00000599857.1
ENST00000593887.1
POLD1



polymerase (DNA directed), delta 1, catalytic subunit



chr16_+_29817841 0.694 ENST00000322945.6
ENST00000562337.1
ENST00000566906.2
ENST00000563402.1
ENST00000219782.6
MAZ




MYC-associated zinc finger protein (purine-binding transcription factor)




chr14_+_100437780 0.690 ENST00000402714.2
EVL
Enah/Vasp-like
chr14_+_103243813 0.683 ENST00000560371.1
ENST00000347662.4
ENST00000392745.2
ENST00000539721.1
ENST00000560463.1
TRAF3




TNF receptor-associated factor 3




chr18_-_74207146 0.679 ENST00000443185.2
ZNF516
zinc finger protein 516
chr8_-_28243590 0.675 ENST00000523095.1
ENST00000522795.1
ZNF395

zinc finger protein 395

chr19_+_8274185 0.668 ENST00000558268.1
ENST00000558331.1
CERS4

ceramide synthase 4

chr5_+_157158205 0.663 ENST00000231198.7
THG1L
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr7_-_994302 0.659 ENST00000265846.5
ADAP1
ArfGAP with dual PH domains 1
chr15_-_90645679 0.653 ENST00000539790.1
ENST00000559482.1
ENST00000330062.3
IDH2


isocitrate dehydrogenase 2 (NADP+), mitochondrial


chr5_+_149546334 0.652 ENST00000231656.8
CDX1
caudal type homeobox 1
chr19_+_8274204 0.652 ENST00000561053.1
ENST00000251363.5
ENST00000559450.1
ENST00000559336.1
CERS4



ceramide synthase 4



chr17_-_3599492 0.644 ENST00000435558.1
ENST00000345901.3
P2RX5

purinergic receptor P2X, ligand-gated ion channel, 5

chr11_+_68080077 0.640 ENST00000294304.7
LRP5
low density lipoprotein receptor-related protein 5
chr3_-_121553830 0.640 ENST00000498104.1
ENST00000460108.1
ENST00000349820.6
ENST00000462442.1
ENST00000310864.6
IQCB1




IQ motif containing B1




chr10_+_74033672 0.628 ENST00000307365.3
DDIT4
DNA-damage-inducible transcript 4
chr8_+_38614807 0.627 ENST00000330691.6
ENST00000348567.4
TACC1

transforming, acidic coiled-coil containing protein 1

chr2_+_204193149 0.621 ENST00000422511.2
ABI2
abl-interactor 2
chr6_+_36410762 0.619 ENST00000483557.1
ENST00000498267.1
ENST00000544295.1
ENST00000449081.2
ENST00000536244.1
ENST00000460983.1
KCTD20





potassium channel tetramerization domain containing 20





chr2_+_204193101 0.615 ENST00000430418.1
ENST00000424558.1
ENST00000261016.6
ABI2


abl-interactor 2


chr5_+_612387 0.613 ENST00000264935.5
ENST00000444221.1
CEP72

centrosomal protein 72kDa

chr7_-_148581251 0.611 ENST00000478654.1
ENST00000460911.1
ENST00000350995.2
EZH2


enhancer of zeste homolog 2 (Drosophila)


chr14_-_64971288 0.609 ENST00000394715.1
ZBTB25
zinc finger and BTB domain containing 25
chr19_-_18717627 0.608 ENST00000392386.3
CRLF1
cytokine receptor-like factor 1
chr3_-_53080047 0.608 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
SFMBT1



Scm-like with four mbt domains 1



chr1_+_11751748 0.605 ENST00000294485.5
DRAXIN
dorsal inhibitory axon guidance protein
chr8_+_28351707 0.604 ENST00000537916.1
ENST00000523546.1
ENST00000240093.3
FZD3


frizzled family receptor 3


chr2_+_216176540 0.596 ENST00000236959.9
ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr16_+_2039946 0.594 ENST00000248121.2
ENST00000568896.1
SYNGR3

synaptogyrin 3

chr6_-_119670919 0.594 ENST00000368468.3
MAN1A1
mannosidase, alpha, class 1A, member 1
chr6_-_13711773 0.590 ENST00000011619.3
RANBP9
RAN binding protein 9
chr2_+_97426631 0.589 ENST00000377075.2
CNNM4
cyclin M4
chr13_-_39612176 0.589 ENST00000352251.3
ENST00000350125.3
PROSER1

proline and serine rich 1

chrX_-_48776292 0.588 ENST00000376509.4
PIM2
pim-2 oncogene
chr17_+_30813576 0.588 ENST00000313401.3
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr5_-_78809950 0.588 ENST00000334082.6
HOMER1
homer homolog 1 (Drosophila)
chr1_+_91966656 0.582 ENST00000428239.1
ENST00000426137.1
CDC7

cell division cycle 7

chr6_+_31865552 0.573 ENST00000469372.1
ENST00000497706.1
C2

complement component 2

chr4_+_113152881 0.573 ENST00000274000.5
AP1AR
adaptor-related protein complex 1 associated regulatory protein
chr22_+_50247449 0.571 ENST00000216268.5
ZBED4
zinc finger, BED-type containing 4
chr11_-_35440796 0.559 ENST00000278379.3
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr7_+_1126437 0.558 ENST00000413368.1
ENST00000397092.1
GPER1

G protein-coupled estrogen receptor 1

chr10_+_16478942 0.557 ENST00000535784.2
ENST00000423462.2
ENST00000378000.1
PTER


phosphotriesterase related


chr15_+_52311398 0.546 ENST00000261845.5
MAPK6
mitogen-activated protein kinase 6
chr6_-_13814663 0.541 ENST00000359495.2
ENST00000379170.4
MCUR1

mitochondrial calcium uniporter regulator 1

chr1_-_53793725 0.533 ENST00000371454.2
LRP8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr1_+_167190066 0.530 ENST00000367866.2
ENST00000429375.2
ENST00000452019.1
ENST00000420254.3
ENST00000541643.3
POU2F1




POU class 2 homeobox 1




chr4_+_17812525 0.528 ENST00000251496.2
NCAPG
non-SMC condensin I complex, subunit G
chr1_-_54304212 0.527 ENST00000540001.1
NDC1
NDC1 transmembrane nucleoporin
chr1_-_54303949 0.527 ENST00000234725.8
NDC1
NDC1 transmembrane nucleoporin
chr7_-_99698338 0.521 ENST00000354230.3
ENST00000425308.1
MCM7

minichromosome maintenance complex component 7

chr17_+_72428218 0.521 ENST00000392628.2
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr11_-_113746277 0.517 ENST00000003302.4
ENST00000545540.1
USP28

ubiquitin specific peptidase 28

chr20_+_31407692 0.510 ENST00000375571.5
MAPRE1
microtubule-associated protein, RP/EB family, member 1
chr11_+_65029421 0.510 ENST00000541089.1
POLA2
polymerase (DNA directed), alpha 2, accessory subunit
chr15_-_66084428 0.509 ENST00000443035.3
ENST00000431932.2
DENND4A

DENN/MADD domain containing 4A

chr7_-_105925558 0.502 ENST00000222553.3
NAMPT
nicotinamide phosphoribosyltransferase
chr6_+_57037089 0.500 ENST00000370693.5
BAG2
BCL2-associated athanogene 2
chr7_+_138145145 0.499 ENST00000415680.2
TRIM24
tripartite motif containing 24
chr8_-_94753229 0.498 ENST00000518597.1
ENST00000399300.2
ENST00000517700.1
RBM12B


RNA binding motif protein 12B


chr16_-_72127550 0.485 ENST00000268483.3
TXNL4B
thioredoxin-like 4B
chr7_-_148581360 0.485 ENST00000320356.2
ENST00000541220.1
ENST00000483967.1
ENST00000536783.1
EZH2



enhancer of zeste homolog 2 (Drosophila)



chr11_-_46142615 0.484 ENST00000529734.1
ENST00000323180.6
PHF21A

PHD finger protein 21A

chr2_-_10588630 0.483 ENST00000234111.4
ODC1
ornithine decarboxylase 1
chr14_-_53162361 0.483 ENST00000395686.3
ERO1L
ERO1-like (S. cerevisiae)
chr2_-_225907150 0.482 ENST00000258390.7
DOCK10
dedicator of cytokinesis 10
chr3_+_133292851 0.479 ENST00000503932.1
CDV3
CDV3 homolog (mouse)
chr11_-_113746212 0.473 ENST00000537642.1
ENST00000537706.1
ENST00000544750.1
ENST00000260188.5
ENST00000540925.1
USP28




ubiquitin specific peptidase 28




chr20_+_60697480 0.472 ENST00000370915.1
ENST00000253001.4
ENST00000400318.2
ENST00000279068.6
ENST00000279069.7
LSM14B




LSM14B, SCD6 homolog B (S. cerevisiae)




chr3_+_184080790 0.472 ENST00000430783.1
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr13_+_43148281 0.471 ENST00000239849.6
ENST00000398795.2
ENST00000544862.1
TNFSF11


tumor necrosis factor (ligand) superfamily, member 11


chr16_+_84733575 0.468 ENST00000219473.7
ENST00000563892.1
ENST00000562283.1
ENST00000570191.1
ENST00000569038.1
ENST00000570053.1
USP10





ubiquitin specific peptidase 10





chr16_-_56459354 0.461 ENST00000290649.5
AMFR
autocrine motility factor receptor, E3 ubiquitin protein ligase
chr13_-_21099935 0.456 ENST00000298248.7
ENST00000382812.1
CRYL1

crystallin, lambda 1

chr14_+_76044934 0.454 ENST00000238667.4
FLVCR2
feline leukemia virus subgroup C cellular receptor family, member 2
chr16_+_67596310 0.451 ENST00000264010.4
ENST00000401394.1
CTCF

CCCTC-binding factor (zinc finger protein)

chr7_-_139477500 0.450 ENST00000406875.3
ENST00000428878.2
HIPK2

homeodomain interacting protein kinase 2

chr8_-_145515055 0.449 ENST00000526552.1
ENST00000529231.1
ENST00000307404.5
BOP1


block of proliferation 1


chr11_-_35441524 0.448 ENST00000395750.1
ENST00000449068.1
SLC1A2

solute carrier family 1 (glial high affinity glutamate transporter), member 2

chr11_+_20691099 0.447 ENST00000298925.5
ENST00000357134.5
ENST00000325319.5
NELL1


NEL-like 1 (chicken)


chr9_-_112083229 0.446 ENST00000374566.3
ENST00000374557.4
EPB41L4B

erythrocyte membrane protein band 4.1 like 4B

chr19_+_35759824 0.446 ENST00000343550.5
USF2
upstream transcription factor 2, c-fos interacting
chr3_-_148804275 0.440 ENST00000392912.2
ENST00000465259.1
ENST00000310053.5
ENST00000494055.1
HLTF



helicase-like transcription factor



chr12_-_108954933 0.439 ENST00000431469.2
ENST00000546815.1
SART3

squamous cell carcinoma antigen recognized by T cells 3

chr1_-_45805667 0.438 ENST00000488731.2
ENST00000435155.1
MUTYH

mutY homolog

chr11_+_64863587 0.434 ENST00000530773.1
ENST00000279281.3
ENST00000529180.1
VPS51


vacuolar protein sorting 51 homolog (S. cerevisiae)


chr6_-_143266297 0.434 ENST00000367603.2
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr19_+_35759968 0.431 ENST00000222305.3
ENST00000595068.1
ENST00000379134.3
ENST00000594064.1
ENST00000598058.1
USF2




upstream transcription factor 2, c-fos interacting




chr7_+_73703728 0.428 ENST00000361545.5
ENST00000223398.6
CLIP2

CAP-GLY domain containing linker protein 2

chr20_+_30946106 0.420 ENST00000375687.4
ENST00000542461.1
ASXL1

additional sex combs like 1 (Drosophila)

chr1_-_101491319 0.417 ENST00000342173.7
ENST00000488176.1
ENST00000370109.3
DPH5


diphthamide biosynthesis 5


chr1_-_54303934 0.415 ENST00000537333.1
NDC1
NDC1 transmembrane nucleoporin
chr9_-_15510989 0.413 ENST00000380715.1
ENST00000380716.4
ENST00000380738.4
ENST00000380733.4
PSIP1



PC4 and SFRS1 interacting protein 1



chr16_+_10837643 0.413 ENST00000574334.1
ENST00000283027.5
ENST00000433392.2
NUBP1


nucleotide binding protein 1


chr19_+_42724423 0.412 ENST00000301215.3
ENST00000597945.1
ZNF526

zinc finger protein 526

chr12_-_92539614 0.412 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr12_-_108955070 0.410 ENST00000228284.3
ENST00000546611.1
SART3

squamous cell carcinoma antigen recognized by T cells 3

chr4_+_113152978 0.409 ENST00000309703.6
AP1AR
adaptor-related protein complex 1 associated regulatory protein
chr1_-_45805607 0.405 ENST00000372104.1
ENST00000448481.1
ENST00000483127.1
ENST00000528013.2
ENST00000456914.2
MUTYH




mutY homolog




chr6_+_89790490 0.396 ENST00000336032.3
PNRC1
proline-rich nuclear receptor coactivator 1
chr6_+_56954808 0.395 ENST00000510483.1
ENST00000370706.4
ENST00000357489.3
ZNF451


zinc finger protein 451


chr21_-_44846999 0.394 ENST00000270162.6
SIK1
salt-inducible kinase 1
chr2_-_62733476 0.394 ENST00000335390.5
TMEM17
transmembrane protein 17
chr6_+_89790459 0.391 ENST00000369472.1
PNRC1
proline-rich nuclear receptor coactivator 1
chr9_+_116037922 0.391 ENST00000374198.4
PRPF4
pre-mRNA processing factor 4
chr19_+_39833036 0.390 ENST00000602243.1
ENST00000598913.1
ENST00000314471.6
SAMD4B


sterile alpha motif domain containing 4B


chr9_-_120177216 0.389 ENST00000373996.3
ENST00000313400.4
ENST00000361477.3
ASTN2


astrotactin 2


chr17_+_29718642 0.388 ENST00000325874.8
RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr6_+_43738444 0.388 ENST00000324450.6
ENST00000417285.2
ENST00000413642.3
ENST00000372055.4
ENST00000482630.2
ENST00000425836.2
ENST00000372064.4
ENST00000372077.4
ENST00000519767.1
VEGFA








vascular endothelial growth factor A








chr18_-_12377283 0.385 ENST00000269143.3
AFG3L2
AFG3-like AAA ATPase 2
chr22_-_19137796 0.381 ENST00000086933.2
GSC2
goosecoid homeobox 2
chr1_-_212004090 0.381 ENST00000366997.4
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr2_-_176032843 0.381 ENST00000392544.1
ENST00000409499.1
ENST00000426833.3
ENST00000392543.2
ENST00000538946.1
ENST00000487334.2
ENST00000409833.1
ENST00000409635.1
ENST00000264110.2
ENST00000345739.5
ATF2









activating transcription factor 2









chr7_-_139876812 0.381 ENST00000397560.2
JHDM1D
lysine (K)-specific demethylase 7A
chr8_+_41386725 0.379 ENST00000276533.3
ENST00000520710.1
ENST00000518671.1
GINS4


GINS complex subunit 4 (Sld5 homolog)


chr1_+_28844648 0.378 ENST00000373832.1
ENST00000373831.3
RCC1

regulator of chromosome condensation 1

chr19_-_16582754 0.375 ENST00000602151.1
ENST00000597937.1
ENST00000535753.2
EPS15L1


epidermal growth factor receptor pathway substrate 15-like 1


chr2_+_232572361 0.374 ENST00000409321.1
PTMA
prothymosin, alpha
chr19_+_5823813 0.374 ENST00000303212.2
NRTN
neurturin
chr3_-_50540854 0.370 ENST00000423994.2
ENST00000424201.2
ENST00000479441.1
ENST00000429770.1
CACNA2D2



calcium channel, voltage-dependent, alpha 2/delta subunit 2



chr19_+_10982336 0.370 ENST00000344150.4
CARM1
coactivator-associated arginine methyltransferase 1
chr1_+_110198944 0.370 ENST00000369833.1
GSTM4
glutathione S-transferase mu 4
chr22_-_31885514 0.370 ENST00000397525.1
EIF4ENIF1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr14_-_64970494 0.367 ENST00000608382.1
ZBTB25
zinc finger and BTB domain containing 25
chr11_+_65029233 0.365 ENST00000265465.3
POLA2
polymerase (DNA directed), alpha 2, accessory subunit
chr2_-_136743169 0.361 ENST00000264161.4
DARS
aspartyl-tRNA synthetase
chr16_+_19535235 0.360 ENST00000565376.2
ENST00000396208.2
CCP110

centriolar coiled coil protein 110kDa

chr7_+_1126461 0.360 ENST00000297469.3
GPER1
G protein-coupled estrogen receptor 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.9 2.8 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.6 1.8 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.4 1.3 GO:0046102 inosine metabolic process(GO:0046102)
0.4 1.3 GO:0061117 negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.4 1.2 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.3 1.0 GO:0071848 regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) TNFSF11-mediated signaling pathway(GO:0071847) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.3 0.9 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.3 0.9 GO:0046015 carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015) positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.2 0.7 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.2 0.2 GO:0016458 gene silencing(GO:0016458)
0.2 1.4 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.2 0.7 GO:0006273 lagging strand elongation(GO:0006273)
0.2 0.9 GO:0033197 response to vitamin E(GO:0033197)
0.2 0.7 GO:0006097 glyoxylate cycle(GO:0006097)
0.2 0.7 GO:0019919 pathogenesis(GO:0009405) peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.2 0.6 GO:0061298 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.2 0.6 GO:0048496 maintenance of organ identity(GO:0048496)
0.2 0.8 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.2 1.4 GO:0045007 depurination(GO:0045007)
0.2 0.6 GO:0021754 facial nucleus development(GO:0021754) cell proliferation in midbrain(GO:0033278)
0.2 2.2 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.2 1.2 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.2 0.6 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.2 1.0 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.2 0.6 GO:0003011 diaphragm contraction(GO:0002086) involuntary skeletal muscle contraction(GO:0003011)
0.2 0.9 GO:0003093 regulation of glomerular filtration(GO:0003093) glomerular filtration(GO:0003094) renal filtration(GO:0097205) regulation of renal system process(GO:0098801)
0.2 3.4 GO:0006386 transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.2 0.5 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.2 1.2 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.2 0.5 GO:1901419 regulation of response to alcohol(GO:1901419)
0.2 0.8 GO:0006857 oligopeptide transport(GO:0006857)
0.2 0.6 GO:0034629 cellular protein complex localization(GO:0034629)
0.2 0.5 GO:0002575 basophil chemotaxis(GO:0002575)
0.2 0.3 GO:0031648 protein destabilization(GO:0031648)
0.2 0.5 GO:0070601 maintenance of DNA methylation(GO:0010216) centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.1 1.3 GO:0007090 obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.1 0.4 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 0.8 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.4 GO:0043276 anoikis(GO:0043276)
0.1 0.9 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 1.1 GO:0001706 endoderm formation(GO:0001706)
0.1 0.5 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1 0.2 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 1.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.4 GO:0035623 renal glucose absorption(GO:0035623)
0.1 0.5 GO:0014040 regulation of Schwann cell differentiation(GO:0014038) positive regulation of Schwann cell differentiation(GO:0014040)
0.1 0.6 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 0.9 GO:0006188 IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.1 0.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.1 0.9 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.6 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.5 GO:0044380 protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.1 0.3 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.1 0.4 GO:0060013 righting reflex(GO:0060013)
0.1 0.3 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 0.5 GO:0045778 positive regulation of ossification(GO:0045778)
0.1 0.2 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.1 1.0 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.1 0.9 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.1 0.3 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.1 0.2 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 0.4 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.1 0.3 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.1 0.4 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.3 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.2 GO:0021769 orbitofrontal cortex development(GO:0021769) ventricular zone neuroblast division(GO:0021847) fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development(GO:0035607) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
0.1 0.3 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.1 0.3 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1 0.3 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.1 0.3 GO:0019985 translesion synthesis(GO:0019985)
0.1 1.0 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.5 GO:0009820 alkaloid metabolic process(GO:0009820)
0.1 0.2 GO:0014063 regulation of serotonin secretion(GO:0014062) negative regulation of serotonin secretion(GO:0014063)
0.1 0.9 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 0.3 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 0.3 GO:0042816 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.1 0.3 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1 0.3 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.2 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.1 2.3 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.1 0.2 GO:0000114 obsolete regulation of transcription involved in G1 phase of mitotic cell cycle(GO:0000114)
0.1 1.0 GO:0051319 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.1 0.4 GO:0043457 regulation of cellular respiration(GO:0043457)
0.1 0.2 GO:2000078 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287) regulation of type B pancreatic cell development(GO:2000074) positive regulation of type B pancreatic cell development(GO:2000078)
0.1 0.3 GO:0001510 RNA methylation(GO:0001510)
0.1 0.6 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.2 GO:0050804 modulation of synaptic transmission(GO:0050804)
0.1 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.6 GO:0033261 obsolete regulation of S phase(GO:0033261)
0.1 0.5 GO:0015886 heme transport(GO:0015886)
0.1 0.3 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.1 GO:0032481 positive regulation of type I interferon production(GO:0032481) positive regulation of interferon-alpha production(GO:0032727)
0.0 0.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 4.5 GO:0006094 gluconeogenesis(GO:0006094)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.6 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 0.4 GO:0046831 regulation of nucleobase-containing compound transport(GO:0032239) regulation of RNA export from nucleus(GO:0046831)
0.0 1.3 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 2.3 GO:0060041 retina development in camera-type eye(GO:0060041)
0.0 0.3 GO:0051383 kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383)
0.0 0.3 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.7 GO:0006400 tRNA modification(GO:0006400)
0.0 0.3 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.7 GO:0050812 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.1 GO:0001941 postsynaptic membrane organization(GO:0001941)
0.0 0.0 GO:1902116 negative regulation of organelle assembly(GO:1902116)
0.0 0.8 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.9 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968) cellular response to unfolded protein(GO:0034620)
0.0 0.1 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.1 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0 0.1 GO:0051597 response to methylmercury(GO:0051597)
0.0 0.2 GO:0006983 ER overload response(GO:0006983)
0.0 0.7 GO:0032608 interferon-beta production(GO:0032608) regulation of interferon-beta production(GO:0032648)
0.0 0.1 GO:0060318 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361) definitive erythrocyte differentiation(GO:0060318)
0.0 0.1 GO:0070091 glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.0 0.3 GO:0007143 female meiotic division(GO:0007143)
0.0 1.4 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.6 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.4 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.3 GO:1901019 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314) regulation of calcium ion transmembrane transporter activity(GO:1901019) regulation of cation channel activity(GO:2001257)
0.0 0.3 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.1 GO:0071168 negative regulation of sister chromatid cohesion(GO:0045875) protein localization to chromatin(GO:0071168)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.2 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.4 GO:0046037 phototransduction, visible light(GO:0007603) GMP metabolic process(GO:0046037)
0.0 0.1 GO:0021684 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.4 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.2 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.2 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.7 GO:0014823 response to activity(GO:0014823)
0.0 0.2 GO:0034969 histone arginine methylation(GO:0034969)
0.0 0.2 GO:0043545 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.2 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.1 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.3 GO:1901984 negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0 0.2 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 2.5 GO:0043010 camera-type eye development(GO:0043010)
0.0 0.2 GO:0031427 response to methotrexate(GO:0031427)
0.0 2.1 GO:0050680 negative regulation of epithelial cell proliferation(GO:0050680)
0.0 0.4 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.1 GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.0 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.0 GO:0060992 response to fungicide(GO:0060992)
0.0 0.3 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.3 GO:0046902 regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.2 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.1 GO:0006896 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.3 GO:0051051 negative regulation of transport(GO:0051051)
0.0 3.1 GO:0006333 chromatin assembly or disassembly(GO:0006333)
0.0 0.5 GO:0072331 signal transduction by p53 class mediator(GO:0072331)
0.0 0.9 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.2 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.1 GO:0003416 endochondral bone growth(GO:0003416) growth plate cartilage development(GO:0003417) bone growth(GO:0098868)
0.0 1.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.6 GO:0031214 biomineral tissue development(GO:0031214)
0.0 0.2 GO:0046051 GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) GTP metabolic process(GO:0046039) UTP metabolic process(GO:0046051) guanosine-containing compound biosynthetic process(GO:1901070)
0.0 0.2 GO:0075713 establishment of viral latency(GO:0019043) establishment of integrated proviral latency(GO:0075713)
0.0 0.1 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.7 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.2 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 0.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.2 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.1 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.3 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.0 0.2 GO:0051928 positive regulation of calcium ion transport(GO:0051928)
0.0 0.3 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.4 GO:0021675 nerve development(GO:0021675)
0.0 0.3 GO:0098657 neurotransmitter uptake(GO:0001504) import into cell(GO:0098657)
0.0 0.1 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.3 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.7 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.1 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.0 GO:0045814 negative regulation of gene expression, epigenetic(GO:0045814)
0.0 0.3 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.0 0.2 GO:0006906 vesicle fusion(GO:0006906)
0.0 0.6 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.1 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.1 GO:0061756 leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.4 1.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.3 1.0 GO:0000802 transverse filament(GO:0000802)
0.2 1.3 GO:0001741 XY body(GO:0001741)
0.2 0.5 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.2 0.5 GO:0005726 perichromatin fibrils(GO:0005726)
0.2 0.8 GO:0001740 Barr body(GO:0001740)
0.2 2.1 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.6 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.6 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.9 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 3.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.4 GO:0071001 U4/U6 snRNP(GO:0071001)
0.1 1.4 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.1 0.6 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.4 GO:0070545 PeBoW complex(GO:0070545)
0.1 1.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.7 GO:0042575 DNA polymerase complex(GO:0042575)
0.1 1.2 GO:0030673 axolemma(GO:0030673)
0.1 0.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 0.3 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 0.9 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.3 GO:0036125 mitochondrial fatty acid beta-oxidation multienzyme complex(GO:0016507) fatty acid beta-oxidation multienzyme complex(GO:0036125)
0.1 0.9 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 0.7 GO:0000796 condensin complex(GO:0000796)
0.1 0.4 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 0.3 GO:0044462 external encapsulating structure part(GO:0044462)
0.1 5.8 GO:0016605 PML body(GO:0016605)
0.1 0.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 1.9 GO:0000299 obsolete integral to membrane of membrane fraction(GO:0000299)
0.1 0.6 GO:0042555 MCM complex(GO:0042555)
0.1 0.3 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 0.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 3.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.3 GO:0045298 tubulin complex(GO:0045298)
0.0 0.6 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.6 GO:0043034 costamere(GO:0043034)
0.0 0.6 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0002102 podosome(GO:0002102)
0.0 0.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.3 GO:0031941 filamentous actin(GO:0031941)
0.0 0.7 GO:0090568 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 0.1 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.1 GO:0038201 TORC2 complex(GO:0031932) TOR complex(GO:0038201)
0.0 1.0 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.1 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0000145 exocyst(GO:0000145)
0.0 0.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.3 GO:0000125 PCAF complex(GO:0000125)
0.0 1.6 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.2 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.3 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.6 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.2 GO:0030681 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 0.3 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0030118 clathrin coat(GO:0030118) clathrin adaptor complex(GO:0030131)
0.0 2.3 GO:0016607 nuclear speck(GO:0016607)
0.0 0.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.5 GO:0016460 myosin II complex(GO:0016460)
0.0 0.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0005858 axonemal dynein complex(GO:0005858) axoneme part(GO:0044447)
0.0 0.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 2.1 GO:0019717 obsolete synaptosome(GO:0019717)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 1.3 GO:0000793 condensed chromosome(GO:0000793)
0.0 2.2 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.3 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 2.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.3 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.0 0.4 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.0 GO:0042598 obsolete vesicular fraction(GO:0042598)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) exoribonuclease II activity(GO:0008859)
0.9 2.8 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.7 4.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.4 1.8 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.4 1.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.4 1.2 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.4 1.4 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.3 1.7 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3 0.8 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.2 0.7 GO:0051765 obsolete inositol-1,3,4-trisphosphate 5/6-kinase activity(GO:0035300) inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765)
0.2 1.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.2 0.7 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.2 0.7 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.2 0.7 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.2 1.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 0.6 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.2 2.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 0.6 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.2 0.8 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.2 1.4 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.2 0.7 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.2 0.5 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.2 0.7 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.1 0.6 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.1 1.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 0.2 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 0.9 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 2.5 GO:0070064 proline-rich region binding(GO:0070064)
0.1 1.3 GO:0019841 retinol binding(GO:0019841)
0.1 0.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 0.6 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.1 0.6 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.6 GO:0019238 cyclohydrolase activity(GO:0019238)
0.1 0.3 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 0.3 GO:0031402 sodium ion binding(GO:0031402)
0.1 0.5 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 0.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 1.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 1.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.3 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.1 0.2 GO:0004146 dihydrofolate reductase activity(GO:0004146)
0.1 0.2 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.9 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.3 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 0.3 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 0.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.3 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.1 1.1 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 3.4 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 0.6 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.4 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.3 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.5 GO:0004835 tubulin-tyrosine ligase activity(GO:0004835)
0.1 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.5 GO:0034056 estrogen response element binding(GO:0034056)
0.1 1.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.6 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.2 GO:0030151 molybdenum ion binding(GO:0030151)
0.1 1.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.4 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.1 0.5 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.3 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.5 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.5 GO:0016944 obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0 0.5 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.3 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.8 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.0 0.2 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.4 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.6 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.3 GO:0046790 virion binding(GO:0046790)
0.0 1.7 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.2 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.4 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.2 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.4 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.6 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 1.5 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0048039 succinate dehydrogenase activity(GO:0000104) ubiquinone binding(GO:0048039)
0.0 0.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0004883 glucocorticoid receptor activity(GO:0004883)
0.0 1.1 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.1 GO:0004741 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.4 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.3 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.3 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.2 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0017069 snRNA binding(GO:0017069)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.8 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.5 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.2 GO:0008237 metallopeptidase activity(GO:0008237)
0.0 0.6 GO:0019955 cytokine binding(GO:0019955)
0.0 0.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.9 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.4 GO:0001228 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.2 GO:0003709 obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0 0.4 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.2 GO:0008026 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.2 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.1 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.2 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.1 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.0 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0016918 retinal binding(GO:0016918)
0.0 0.4 GO:0004386 helicase activity(GO:0004386)
0.0 0.5 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.3 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.4 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.5 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.1 GO:0015250 water channel activity(GO:0015250)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.5 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.6 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway