Motif ID: HES7_HES5
Z-value: 1.475
Transcription factors associated with HES7_HES5:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
HES5 | ENSG00000197921.5 | HES5 |
HES7 | ENSG00000179111.4 | HES7 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 2.5 | GO:0033578 | protein glycosylation in Golgi(GO:0033578) |
0.3 | 1.3 | GO:0060662 | tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662) |
0.2 | 2.0 | GO:0060216 | definitive hemopoiesis(GO:0060216) |
0.1 | 2.1 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
0.1 | 0.3 | GO:0021529 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780) stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867) |
0.1 | 0.7 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
0.1 | 0.2 | GO:0006307 | DNA dealkylation involved in DNA repair(GO:0006307) DNA dealkylation(GO:0035510) |
0.1 | 0.2 | GO:0050758 | thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760) |
0.1 | 0.2 | GO:0017014 | protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119) |
0.1 | 0.2 | GO:0060120 | auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120) |
0.1 | 1.7 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
0.1 | 0.5 | GO:0006069 | ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069) |
0.0 | 1.2 | GO:0018208 | peptidyl-proline modification(GO:0018208) |
0.0 | 0.1 | GO:0051771 | negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) |
0.0 | 0.4 | GO:0007141 | male meiosis I(GO:0007141) |
0.0 | 0.5 | GO:0095500 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145) |
0.0 | 0.1 | GO:0048073 | regulation of eye pigmentation(GO:0048073) |
0.0 | 0.3 | GO:0007216 | G-protein coupled glutamate receptor signaling pathway(GO:0007216) |
0.0 | 0.3 | GO:0051205 | protein insertion into membrane(GO:0051205) |
0.0 | 0.1 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
0.0 | 0.1 | GO:0032328 | alanine transport(GO:0032328) |
0.0 | 0.2 | GO:0000012 | single strand break repair(GO:0000012) |
0.0 | 0.1 | GO:0018106 | peptidyl-histidine phosphorylation(GO:0018106) |
0.0 | 0.1 | GO:0033147 | negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147) |
0.0 | 0.6 | GO:0051865 | protein autoubiquitination(GO:0051865) |
0.0 | 0.2 | GO:0000301 | retrograde transport, vesicle recycling within Golgi(GO:0000301) |
0.0 | 0.7 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
0.0 | 0.5 | GO:0030593 | neutrophil chemotaxis(GO:0030593) neutrophil migration(GO:1990266) |
0.0 | 0.0 | GO:0071436 | sodium ion export(GO:0071436) |
0.0 | 0.1 | GO:0050685 | positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313) |
0.0 | 2.2 | GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 2.9 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
0.2 | 2.7 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
0.1 | 0.5 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
0.1 | 0.5 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
0.1 | 0.4 | GO:0000800 | lateral element(GO:0000800) |
0.1 | 0.4 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
0.1 | 0.4 | GO:0016012 | sarcoglycan complex(GO:0016012) |
0.0 | 1.9 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
0.0 | 3.7 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
0.0 | 1.3 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
0.0 | 1.3 | GO:0005802 | trans-Golgi network(GO:0005802) |
0.0 | 0.1 | GO:0033391 | chromatoid body(GO:0033391) |
0.0 | 0.0 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
0.0 | 0.0 | GO:0031262 | Ndc80 complex(GO:0031262) |
0.0 | 0.5 | GO:0098636 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
0.0 | 0.3 | GO:0043596 | nuclear replication fork(GO:0043596) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 2.5 | GO:0008424 | glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921) |
0.2 | 1.3 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
0.2 | 0.5 | GO:0016534 | cyclin-dependent protein kinase 5 activator activity(GO:0016534) |
0.1 | 0.6 | GO:0004030 | aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030) |
0.1 | 0.5 | GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308) |
0.1 | 3.0 | GO:0017137 | Rab GTPase binding(GO:0017137) |
0.0 | 0.1 | GO:0004662 | CAAX-protein geranylgeranyltransferase activity(GO:0004662) |
0.0 | 0.2 | GO:0043891 | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891) |
0.0 | 0.2 | GO:0070259 | tyrosyl-DNA phosphodiesterase activity(GO:0070259) |
0.0 | 1.2 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.0 | 0.2 | GO:0042808 | obsolete neuronal Cdc2-like kinase binding(GO:0042808) |
0.0 | 0.5 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
0.0 | 1.1 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.0 | 0.8 | GO:0004623 | phospholipase A2 activity(GO:0004623) |
0.0 | 0.2 | GO:0009008 | DNA-methyltransferase activity(GO:0009008) |
0.0 | 0.1 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
0.0 | 1.0 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
0.0 | 2.6 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
0.0 | 0.1 | GO:0015193 | L-proline transmembrane transporter activity(GO:0015193) |
0.0 | 2.8 | GO:0005178 | integrin binding(GO:0005178) |
0.0 | 0.1 | GO:0005113 | patched binding(GO:0005113) |
0.0 | 0.1 | GO:0008900 | hydrogen:potassium-exchanging ATPase activity(GO:0008900) |
0.0 | 0.3 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
0.0 | 1.3 | GO:0001948 | glycoprotein binding(GO:0001948) |
0.0 | 2.1 | GO:0015631 | tubulin binding(GO:0015631) |
0.0 | 1.4 | GO:0031072 | heat shock protein binding(GO:0031072) |
0.0 | 1.2 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.0 | 0.1 | GO:0003709 | obsolete RNA polymerase III transcription factor activity(GO:0003709) |
0.0 | 0.6 | GO:0002039 | p53 binding(GO:0002039) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 2.6 | SA_FAS_SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
0.0 | 0.2 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |