Motif ID: HLF_TEF
Z-value: 0.742
Transcription factors associated with HLF_TEF:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
HLF | ENSG00000108924.9 | HLF |
TEF | ENSG00000167074.10 | TEF |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.8 | GO:0050965 | detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965) |
0.5 | 3.3 | GO:0032460 | negative regulation of protein oligomerization(GO:0032460) negative regulation of protein homooligomerization(GO:0032463) |
0.1 | 0.8 | GO:0008228 | opsonization(GO:0008228) |
0.1 | 0.3 | GO:0035608 | protein deglutamylation(GO:0035608) |
0.1 | 0.2 | GO:0006982 | response to lipid hydroperoxide(GO:0006982) |
0.1 | 0.2 | GO:0060012 | synaptic transmission, glycinergic(GO:0060012) |
0.0 | 0.5 | GO:0098927 | early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927) |
0.0 | 0.1 | GO:0018076 | N-terminal peptidyl-lysine acetylation(GO:0018076) response to cobalt ion(GO:0032025) |
0.0 | 0.3 | GO:0090005 | negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376) |
0.0 | 0.3 | GO:0008354 | germ cell migration(GO:0008354) |
0.0 | 0.5 | GO:0000301 | retrograde transport, vesicle recycling within Golgi(GO:0000301) |
0.0 | 0.5 | GO:1901797 | negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797) |
0.0 | 0.2 | GO:0060049 | short-term memory(GO:0007614) regulation of protein ADP-ribosylation(GO:0010835) nitric oxide homeostasis(GO:0033484) regulation of protein glycosylation(GO:0060049) |
0.0 | 0.3 | GO:0040037 | negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037) |
0.0 | 0.2 | GO:0090080 | positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080) |
0.0 | 0.2 | GO:0033160 | positive regulation of protein import into nucleus, translocation(GO:0033160) |
0.0 | 0.8 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
0.0 | 0.2 | GO:0060666 | dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666) |
0.0 | 0.3 | GO:0051281 | positive regulation of release of sequestered calcium ion into cytosol(GO:0051281) |
0.0 | 0.1 | GO:0000266 | mitochondrial fission(GO:0000266) |
0.0 | 0.3 | GO:0043392 | negative regulation of DNA binding(GO:0043392) |
0.0 | 0.1 | GO:0032650 | regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) |
0.0 | 0.2 | GO:0016601 | Rac protein signal transduction(GO:0016601) |
0.0 | 0.2 | GO:0006491 | N-glycan processing(GO:0006491) |
0.0 | 0.0 | GO:0002025 | vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 3.1 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
0.1 | 0.5 | GO:0070695 | FHF complex(GO:0070695) |
0.1 | 0.5 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
0.0 | 0.8 | GO:0042612 | MHC class I protein complex(GO:0042612) |
0.0 | 2.3 | GO:0016459 | myosin complex(GO:0016459) |
0.0 | 0.2 | GO:0098651 | basement membrane collagen trimer(GO:0098651) |
0.0 | 0.1 | GO:0005869 | dynactin complex(GO:0005869) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 3.7 | GO:0051787 | misfolded protein binding(GO:0051787) |
0.2 | 2.8 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.1 | 0.3 | GO:0004947 | bradykinin receptor activity(GO:0004947) |
0.1 | 0.8 | GO:0030247 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
0.0 | 0.3 | GO:0042392 | sphingosine-1-phosphate phosphatase activity(GO:0042392) |
0.0 | 0.2 | GO:0016933 | extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934) |
0.0 | 0.5 | GO:0030346 | protein phosphatase 2B binding(GO:0030346) |
0.0 | 0.2 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
0.0 | 0.2 | GO:0045499 | chemorepellent activity(GO:0045499) |
0.0 | 0.2 | GO:0016312 | inositol bisphosphate phosphatase activity(GO:0016312) |
0.0 | 0.6 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
0.0 | 0.2 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
0.0 | 0.6 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.0 | 0.6 | GO:0004385 | guanylate kinase activity(GO:0004385) |
0.0 | 0.3 | GO:0004065 | arylsulfatase activity(GO:0004065) |
0.0 | 0.1 | GO:0042975 | glucocorticoid receptor binding(GO:0035259) peroxisome proliferator activated receptor binding(GO:0042975) |
0.0 | 0.2 | GO:0061659 | ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659) |
0.0 | 0.3 | GO:0005522 | profilin binding(GO:0005522) |
0.0 | 0.3 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
0.0 | 0.1 | GO:0015355 | secondary active monocarboxylate transmembrane transporter activity(GO:0015355) |
0.0 | 1.0 | GO:0015171 | amino acid transmembrane transporter activity(GO:0015171) |
0.0 | 0.0 | GO:0070052 | collagen V binding(GO:0070052) |
0.0 | 0.2 | GO:1900750 | glutathione binding(GO:0043295) oligopeptide binding(GO:1900750) |
0.0 | 0.0 | GO:0004939 | beta-adrenergic receptor activity(GO:0004939) |
0.0 | 0.1 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.6 | SA_TRKA_RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
0.0 | 0.8 | ST_MYOCYTE_AD_PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |