Motif ID: HNF4G
Z-value: 2.348
Transcription factors associated with HNF4G:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
HNF4G | ENSG00000164749.7 | HNF4G |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.4 | 7.3 | GO:0010902 | positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902) positive regulation of phospholipid catabolic process(GO:0060697) |
1.4 | 8.2 | GO:0032460 | negative regulation of protein oligomerization(GO:0032460) negative regulation of protein homooligomerization(GO:0032463) |
1.3 | 4.0 | GO:0010989 | regulation of high-density lipoprotein particle clearance(GO:0010982) negative regulation of low-density lipoprotein particle clearance(GO:0010989) regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910) |
1.2 | 4.6 | GO:0001969 | activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969) positive regulation of activation of membrane attack complex(GO:0001970) positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259) |
1.0 | 3.1 | GO:0032571 | response to vitamin K(GO:0032571) |
0.8 | 2.4 | GO:0060539 | diaphragm development(GO:0060539) |
0.8 | 5.5 | GO:0060414 | aorta development(GO:0035904) aorta morphogenesis(GO:0035909) aorta smooth muscle tissue morphogenesis(GO:0060414) |
0.8 | 3.1 | GO:0033986 | response to methanol(GO:0033986) response to chromate(GO:0046687) |
0.7 | 2.0 | GO:1903115 | regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115) |
0.6 | 1.9 | GO:0014063 | regulation of serotonin secretion(GO:0014062) negative regulation of serotonin secretion(GO:0014063) |
0.5 | 2.7 | GO:0009439 | cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440) |
0.5 | 1.6 | GO:0003176 | aortic valve development(GO:0003176) aortic valve morphogenesis(GO:0003180) notochord formation(GO:0014028) |
0.5 | 1.6 | GO:0010273 | detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169) |
0.5 | 1.6 | GO:0021837 | motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) regulation of mesodermal cell fate specification(GO:0042661) lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378) regulation of mesoderm development(GO:2000380) |
0.5 | 2.9 | GO:0010842 | retina layer formation(GO:0010842) |
0.5 | 1.9 | GO:0071364 | cellular response to epidermal growth factor stimulus(GO:0071364) |
0.4 | 1.6 | GO:0034442 | plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161) |
0.4 | 1.2 | GO:0003289 | septum primum development(GO:0003284) atrial septum primum morphogenesis(GO:0003289) |
0.4 | 1.2 | GO:0001830 | trophectodermal cell fate commitment(GO:0001830) |
0.4 | 3.5 | GO:0046653 | tetrahydrofolate metabolic process(GO:0046653) |
0.3 | 3.3 | GO:0031017 | exocrine pancreas development(GO:0031017) |
0.3 | 2.3 | GO:0007598 | blood coagulation, extrinsic pathway(GO:0007598) |
0.3 | 1.2 | GO:0030913 | paranodal junction assembly(GO:0030913) |
0.3 | 2.6 | GO:0051014 | actin filament severing(GO:0051014) |
0.3 | 1.7 | GO:0032908 | transforming growth factor beta1 production(GO:0032905) regulation of transforming growth factor beta1 production(GO:0032908) |
0.3 | 1.7 | GO:0007500 | mesodermal cell fate determination(GO:0007500) |
0.3 | 0.8 | GO:0097709 | connective tissue replacement involved in inflammatory response wound healing(GO:0002248) elastin metabolic process(GO:0051541) connective tissue replacement(GO:0097709) |
0.3 | 0.8 | GO:0034036 | purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428) |
0.3 | 1.0 | GO:0034337 | RNA folding(GO:0034337) DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) regulation of DNA methylation(GO:0044030) |
0.2 | 0.2 | GO:0006529 | asparagine biosynthetic process(GO:0006529) |
0.2 | 1.8 | GO:1902743 | regulation of lamellipodium assembly(GO:0010591) regulation of lamellipodium organization(GO:1902743) |
0.2 | 0.7 | GO:0032927 | positive regulation of activin receptor signaling pathway(GO:0032927) |
0.2 | 1.8 | GO:0022417 | protein maturation by protein folding(GO:0022417) |
0.2 | 0.7 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
0.2 | 2.2 | GO:0045408 | regulation of interleukin-6 biosynthetic process(GO:0045408) |
0.2 | 0.5 | GO:0001544 | initiation of primordial ovarian follicle growth(GO:0001544) |
0.2 | 0.5 | GO:0035623 | renal glucose absorption(GO:0035623) |
0.1 | 0.7 | GO:0007182 | common-partner SMAD protein phosphorylation(GO:0007182) |
0.1 | 0.6 | GO:0042866 | pyruvate biosynthetic process(GO:0042866) |
0.1 | 0.4 | GO:0046341 | CDP-diacylglycerol metabolic process(GO:0046341) |
0.1 | 1.3 | GO:0000050 | urea cycle(GO:0000050) |
0.1 | 0.7 | GO:0034122 | negative regulation of toll-like receptor signaling pathway(GO:0034122) |
0.1 | 2.5 | GO:0030574 | collagen catabolic process(GO:0030574) |
0.1 | 2.3 | GO:0014037 | Schwann cell differentiation(GO:0014037) tongue development(GO:0043586) |
0.1 | 5.1 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
0.1 | 0.6 | GO:0006422 | aspartyl-tRNA aminoacylation(GO:0006422) |
0.1 | 0.3 | GO:0046984 | regulation of hemoglobin biosynthetic process(GO:0046984) |
0.1 | 0.3 | GO:0045743 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) |
0.1 | 1.0 | GO:0055069 | cellular zinc ion homeostasis(GO:0006882) zinc ion homeostasis(GO:0055069) |
0.1 | 0.4 | GO:0032465 | regulation of cytokinesis(GO:0032465) |
0.1 | 0.2 | GO:0090598 | male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598) |
0.1 | 0.8 | GO:0006013 | mannose metabolic process(GO:0006013) |
0.1 | 0.6 | GO:0050884 | neuromuscular process controlling posture(GO:0050884) |
0.1 | 0.9 | GO:0051016 | barbed-end actin filament capping(GO:0051016) |
0.1 | 1.9 | GO:0015893 | drug transport(GO:0015893) |
0.1 | 5.1 | GO:0042246 | tissue regeneration(GO:0042246) |
0.1 | 1.1 | GO:0006107 | oxaloacetate metabolic process(GO:0006107) |
0.1 | 0.4 | GO:0003070 | age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) |
0.1 | 1.3 | GO:0070670 | response to interleukin-4(GO:0070670) |
0.1 | 0.8 | GO:0009650 | UV protection(GO:0009650) |
0.1 | 0.2 | GO:0060370 | susceptibility to T cell mediated cytotoxicity(GO:0060370) |
0.1 | 2.5 | GO:0003009 | skeletal muscle contraction(GO:0003009) |
0.1 | 5.6 | GO:0032387 | negative regulation of intracellular transport(GO:0032387) |
0.1 | 0.7 | GO:0006069 | ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069) |
0.1 | 0.2 | GO:0018874 | benzoate metabolic process(GO:0018874) |
0.1 | 0.3 | GO:0045091 | regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091) |
0.1 | 0.9 | GO:0043567 | regulation of insulin-like growth factor receptor signaling pathway(GO:0043567) |
0.1 | 5.5 | GO:0031668 | cellular response to extracellular stimulus(GO:0031668) |
0.1 | 0.7 | GO:0018214 | peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214) |
0.1 | 0.5 | GO:0008272 | sulfate transport(GO:0008272) |
0.1 | 4.8 | GO:0017148 | negative regulation of translation(GO:0017148) |
0.1 | 1.2 | GO:0032781 | positive regulation of ATPase activity(GO:0032781) |
0.1 | 0.2 | GO:0016265 | regulation of vascular smooth muscle contraction(GO:0003056) obsolete death(GO:0016265) |
0.1 | 0.4 | GO:2000172 | regulation of branching morphogenesis of a nerve(GO:2000172) |
0.1 | 0.3 | GO:0035058 | nonmotile primary cilium assembly(GO:0035058) |
0.1 | 1.2 | GO:0055010 | ventricular cardiac muscle tissue morphogenesis(GO:0055010) |
0.1 | 0.2 | GO:0003079 | obsolete positive regulation of natriuresis(GO:0003079) response to ozone(GO:0010193) operant conditioning(GO:0035106) positive regulation of action potential(GO:0045760) |
0.1 | 0.7 | GO:0015949 | nucleobase-containing small molecule interconversion(GO:0015949) |
0.1 | 0.2 | GO:0034720 | histone H3-K4 demethylation(GO:0034720) |
0.1 | 0.5 | GO:0035162 | embryonic hemopoiesis(GO:0035162) |
0.0 | 0.7 | GO:0002021 | response to dietary excess(GO:0002021) |
0.0 | 0.2 | GO:0006081 | cellular aldehyde metabolic process(GO:0006081) |
0.0 | 0.2 | GO:0006391 | transcription initiation from mitochondrial promoter(GO:0006391) |
0.0 | 0.6 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
0.0 | 0.3 | GO:0042117 | monocyte activation(GO:0042117) |
0.0 | 0.7 | GO:0032784 | regulation of DNA-templated transcription, elongation(GO:0032784) |
0.0 | 0.8 | GO:0006662 | glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904) |
0.0 | 0.2 | GO:0007256 | activation of JNKK activity(GO:0007256) |
0.0 | 0.1 | GO:0015910 | peroxisomal long-chain fatty acid import(GO:0015910) |
0.0 | 0.1 | GO:0050747 | positive regulation of lipoprotein metabolic process(GO:0050747) |
0.0 | 0.1 | GO:0044321 | cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321) |
0.0 | 0.5 | GO:0001961 | positive regulation of cytokine-mediated signaling pathway(GO:0001961) |
0.0 | 0.6 | GO:0071044 | histone mRNA catabolic process(GO:0071044) |
0.0 | 8.3 | GO:0007517 | muscle organ development(GO:0007517) |
0.0 | 1.2 | GO:0006730 | one-carbon metabolic process(GO:0006730) |
0.0 | 0.7 | GO:0045104 | intermediate filament cytoskeleton organization(GO:0045104) |
0.0 | 0.1 | GO:0060061 | Spemann organizer formation(GO:0060061) |
0.0 | 1.6 | GO:0060271 | cilium morphogenesis(GO:0060271) |
0.0 | 0.7 | GO:0006541 | glutamine metabolic process(GO:0006541) |
0.0 | 0.3 | GO:0043545 | Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189) |
0.0 | 0.1 | GO:0009301 | snRNA transcription(GO:0009301) |
0.0 | 0.8 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
0.0 | 0.7 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
0.0 | 3.3 | GO:0002576 | platelet degranulation(GO:0002576) |
0.0 | 0.9 | GO:0035338 | long-chain fatty-acyl-CoA metabolic process(GO:0035336) long-chain fatty-acyl-CoA biosynthetic process(GO:0035338) |
0.0 | 2.7 | GO:0008360 | regulation of cell shape(GO:0008360) |
0.0 | 0.1 | GO:0009822 | alkaloid catabolic process(GO:0009822) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346) |
0.0 | 1.9 | GO:0030041 | actin filament polymerization(GO:0030041) |
0.0 | 1.0 | GO:0048146 | positive regulation of fibroblast proliferation(GO:0048146) |
0.0 | 0.2 | GO:0006065 | UDP-glucuronate biosynthetic process(GO:0006065) |
0.0 | 3.0 | GO:0018279 | peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279) |
0.0 | 0.8 | GO:0001837 | epithelial to mesenchymal transition(GO:0001837) |
0.0 | 0.9 | GO:0051318 | G1 phase(GO:0051318) |
0.0 | 0.3 | GO:0006071 | glycerol metabolic process(GO:0006071) |
0.0 | 2.8 | GO:0007179 | transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560) |
0.0 | 0.2 | GO:0006551 | leucine metabolic process(GO:0006551) |
0.0 | 0.6 | GO:0005980 | glycogen catabolic process(GO:0005980) |
0.0 | 1.1 | GO:0097479 | synaptic vesicle transport(GO:0048489) synaptic vesicle localization(GO:0097479) establishment of synaptic vesicle localization(GO:0097480) |
0.0 | 0.3 | GO:0006699 | bile acid biosynthetic process(GO:0006699) |
0.0 | 0.3 | GO:0001702 | gastrulation with mouth forming second(GO:0001702) |
0.0 | 0.4 | GO:0042493 | response to drug(GO:0042493) |
0.0 | 0.1 | GO:0015722 | canalicular bile acid transport(GO:0015722) |
0.0 | 0.3 | GO:0006750 | glutathione biosynthetic process(GO:0006750) |
0.0 | 0.3 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
0.0 | 0.9 | GO:0045454 | cell redox homeostasis(GO:0045454) |
0.0 | 0.2 | GO:1901224 | activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224) |
0.0 | 0.2 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
0.0 | 0.1 | GO:0015705 | iodide transport(GO:0015705) |
0.0 | 0.5 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
0.0 | 0.0 | GO:0014887 | muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) striated muscle adaptation(GO:0014888) cardiac muscle hypertrophy in response to stress(GO:0014898) |
0.0 | 0.6 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
0.0 | 0.4 | GO:0080171 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
0.0 | 0.4 | GO:0036503 | ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) ERAD pathway(GO:0036503) |
0.0 | 0.1 | GO:0018345 | protein palmitoylation(GO:0018345) |
0.0 | 0.2 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
0.0 | 0.8 | GO:0006914 | autophagy(GO:0006914) |
0.0 | 0.1 | GO:0060083 | smooth muscle contraction involved in micturition(GO:0060083) |
0.0 | 1.8 | GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123) |
0.0 | 0.7 | GO:0000910 | cytokinesis(GO:0000910) |
0.0 | 1.0 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
0.0 | 0.6 | GO:0009408 | response to heat(GO:0009408) |
0.0 | 0.9 | GO:0030198 | extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062) |
0.0 | 0.3 | GO:0006024 | glycosaminoglycan biosynthetic process(GO:0006024) |
0.0 | 0.6 | GO:0007049 | cell cycle(GO:0007049) |
0.0 | 0.4 | GO:0050771 | negative regulation of axonogenesis(GO:0050771) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.6 | 11.3 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
0.8 | 10.0 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
0.4 | 3.4 | GO:0016012 | sarcoglycan complex(GO:0016012) |
0.4 | 2.4 | GO:0070852 | cell body fiber(GO:0070852) |
0.3 | 3.1 | GO:0042598 | obsolete vesicular fraction(GO:0042598) |
0.2 | 5.9 | GO:0005861 | troponin complex(GO:0005861) |
0.2 | 2.5 | GO:0031233 | intrinsic component of external side of plasma membrane(GO:0031233) |
0.2 | 1.6 | GO:0046581 | intercellular canaliculus(GO:0046581) |
0.1 | 1.6 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.1 | 0.3 | GO:0019008 | molybdopterin synthase complex(GO:0019008) |
0.1 | 2.6 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
0.1 | 0.8 | GO:0034464 | BBSome(GO:0034464) |
0.1 | 6.6 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
0.1 | 0.9 | GO:0005625 | obsolete soluble fraction(GO:0005625) |
0.1 | 1.0 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
0.1 | 1.2 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
0.1 | 2.0 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
0.1 | 0.7 | GO:0005915 | zonula adherens(GO:0005915) |
0.1 | 1.9 | GO:0016328 | lateral plasma membrane(GO:0016328) |
0.1 | 1.0 | GO:0032420 | stereocilium(GO:0032420) |
0.1 | 3.6 | GO:0032432 | actin filament bundle(GO:0032432) |
0.1 | 1.7 | GO:0005776 | autophagosome(GO:0005776) |
0.0 | 0.4 | GO:0042382 | paraspeckles(GO:0042382) |
0.0 | 1.4 | GO:0031526 | brush border membrane(GO:0031526) |
0.0 | 1.9 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
0.0 | 1.0 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
0.0 | 0.7 | GO:0043034 | costamere(GO:0043034) |
0.0 | 0.4 | GO:0000109 | nucleotide-excision repair complex(GO:0000109) |
0.0 | 0.4 | GO:0043202 | lysosomal lumen(GO:0043202) |
0.0 | 0.9 | GO:0005796 | Golgi lumen(GO:0005796) |
0.0 | 2.5 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
0.0 | 0.2 | GO:0005602 | complement component C1 complex(GO:0005602) |
0.0 | 0.3 | GO:0005579 | membrane attack complex(GO:0005579) |
0.0 | 2.8 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
0.0 | 1.4 | GO:0016529 | sarcoplasmic reticulum(GO:0016529) |
0.0 | 24.4 | GO:0005615 | extracellular space(GO:0005615) |
0.0 | 0.4 | GO:0008091 | spectrin(GO:0008091) |
0.0 | 1.6 | GO:0005802 | trans-Golgi network(GO:0005802) |
0.0 | 6.8 | GO:0015629 | actin cytoskeleton(GO:0015629) |
0.0 | 1.0 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
0.0 | 1.4 | GO:0019898 | extrinsic component of membrane(GO:0019898) |
0.0 | 0.2 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
0.0 | 0.1 | GO:0042587 | glycogen granule(GO:0042587) |
0.0 | 0.4 | GO:0055038 | recycling endosome membrane(GO:0055038) |
0.0 | 0.6 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
0.0 | 3.2 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
0.0 | 0.3 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
0.0 | 0.2 | GO:0035631 | CD40 receptor complex(GO:0035631) |
0.0 | 1.0 | GO:0070160 | bicellular tight junction(GO:0005923) occluding junction(GO:0070160) |
0.0 | 0.3 | GO:0030496 | midbody(GO:0030496) |
0.0 | 0.3 | GO:0000795 | synaptonemal complex(GO:0000795) |
0.0 | 1.5 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.5 | 7.3 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
1.1 | 5.5 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
1.0 | 4.0 | GO:0070653 | high-density lipoprotein particle receptor binding(GO:0070653) |
0.9 | 8.2 | GO:0004873 | asialoglycoprotein receptor activity(GO:0004873) |
0.6 | 3.5 | GO:0016647 | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647) |
0.6 | 3.9 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
0.5 | 2.1 | GO:0016784 | 3-mercaptopyruvate sulfurtransferase activity(GO:0016784) |
0.5 | 8.2 | GO:0051787 | misfolded protein binding(GO:0051787) |
0.5 | 2.3 | GO:0034711 | inhibin binding(GO:0034711) |
0.4 | 1.6 | GO:0042910 | xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910) |
0.4 | 1.5 | GO:0016972 | thiol oxidase activity(GO:0016972) |
0.4 | 1.9 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
0.4 | 1.1 | GO:0004476 | mannose-6-phosphate isomerase activity(GO:0004476) |
0.3 | 0.7 | GO:0016362 | activin receptor activity, type II(GO:0016362) |
0.3 | 4.5 | GO:0031014 | troponin T binding(GO:0031014) |
0.3 | 0.6 | GO:0004792 | thiosulfate sulfurtransferase activity(GO:0004792) |
0.3 | 0.8 | GO:0004781 | adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781) |
0.3 | 1.6 | GO:0019863 | IgE binding(GO:0019863) |
0.2 | 1.6 | GO:0004957 | prostaglandin E receptor activity(GO:0004957) |
0.2 | 2.4 | GO:0015643 | toxic substance binding(GO:0015643) |
0.2 | 0.7 | GO:0019215 | intermediate filament binding(GO:0019215) |
0.2 | 1.2 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.2 | 2.4 | GO:0044548 | S100 protein binding(GO:0044548) |
0.2 | 5.4 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
0.2 | 1.3 | GO:0016312 | inositol bisphosphate phosphatase activity(GO:0016312) |
0.2 | 3.9 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
0.2 | 2.5 | GO:0046870 | cadmium ion binding(GO:0046870) |
0.2 | 4.7 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.2 | 0.7 | GO:0004359 | glutaminase activity(GO:0004359) |
0.2 | 0.9 | GO:0045159 | myosin II binding(GO:0045159) |
0.2 | 1.6 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
0.2 | 0.6 | GO:0032810 | sterol response element binding(GO:0032810) |
0.1 | 0.4 | GO:0003881 | CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881) |
0.1 | 0.5 | GO:0008466 | glycogenin glucosyltransferase activity(GO:0008466) |
0.1 | 2.2 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
0.1 | 0.3 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
0.1 | 0.7 | GO:0004030 | aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030) |
0.1 | 1.1 | GO:0009374 | biotin binding(GO:0009374) |
0.1 | 1.2 | GO:0015355 | secondary active monocarboxylate transmembrane transporter activity(GO:0015355) |
0.1 | 0.6 | GO:0004815 | aspartate-tRNA ligase activity(GO:0004815) |
0.1 | 0.3 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
0.1 | 3.3 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
0.1 | 0.3 | GO:0042285 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
0.1 | 0.9 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.1 | 0.4 | GO:0001512 | dihydronicotinamide riboside quinone reductase activity(GO:0001512) |
0.1 | 0.3 | GO:0061505 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
0.1 | 0.3 | GO:0004376 | glycolipid mannosyltransferase activity(GO:0004376) |
0.1 | 0.4 | GO:0004784 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
0.1 | 1.0 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.1 | 1.1 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
0.1 | 0.9 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
0.1 | 0.3 | GO:0005105 | type 1 fibroblast growth factor receptor binding(GO:0005105) |
0.1 | 2.0 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
0.1 | 0.5 | GO:0003997 | acyl-CoA oxidase activity(GO:0003997) |
0.1 | 1.2 | GO:0003756 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
0.1 | 0.6 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
0.1 | 1.2 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
0.1 | 0.3 | GO:0004998 | transferrin receptor activity(GO:0004998) |
0.1 | 1.9 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
0.1 | 0.2 | GO:0003996 | acyl-CoA ligase activity(GO:0003996) |
0.1 | 1.2 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.1 | 0.3 | GO:0005157 | macrophage colony-stimulating factor receptor binding(GO:0005157) |
0.1 | 0.5 | GO:0008271 | secondary active sulfate transmembrane transporter activity(GO:0008271) |
0.1 | 3.3 | GO:0005507 | copper ion binding(GO:0005507) |
0.1 | 3.1 | GO:0002020 | protease binding(GO:0002020) |
0.1 | 0.9 | GO:0050786 | RAGE receptor binding(GO:0050786) |
0.1 | 0.2 | GO:0015142 | citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) |
0.1 | 0.3 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
0.1 | 0.4 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
0.1 | 0.8 | GO:0003706 | obsolete ligand-regulated transcription factor activity(GO:0003706) |
0.1 | 1.4 | GO:0005523 | tropomyosin binding(GO:0005523) |
0.1 | 0.8 | GO:0004128 | cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) |
0.1 | 0.8 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
0.1 | 0.9 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.1 | 0.2 | GO:0043426 | histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648) MRF binding(GO:0043426) |
0.1 | 1.4 | GO:0016646 | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646) |
0.0 | 0.2 | GO:0004066 | asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066) |
0.0 | 0.7 | GO:0004017 | adenylate kinase activity(GO:0004017) |
0.0 | 0.2 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
0.0 | 0.7 | GO:0003711 | obsolete transcription elongation regulator activity(GO:0003711) |
0.0 | 1.3 | GO:0008483 | transaminase activity(GO:0008483) |
0.0 | 0.9 | GO:0033613 | activating transcription factor binding(GO:0033613) |
0.0 | 9.3 | GO:0005125 | cytokine activity(GO:0005125) |
0.0 | 0.9 | GO:0016805 | dipeptidase activity(GO:0016805) |
0.0 | 0.2 | GO:0016641 | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641) |
0.0 | 0.1 | GO:0004608 | phosphatidylethanolamine N-methyltransferase activity(GO:0004608) |
0.0 | 0.9 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
0.0 | 0.2 | GO:0017040 | ceramidase activity(GO:0017040) |
0.0 | 1.8 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
0.0 | 2.4 | GO:0001948 | glycoprotein binding(GO:0001948) |
0.0 | 2.5 | GO:0030165 | PDZ domain binding(GO:0030165) |
0.0 | 3.0 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
0.0 | 0.2 | GO:0004090 | carbonyl reductase (NADPH) activity(GO:0004090) |
0.0 | 0.2 | GO:0004996 | thyroid-stimulating hormone receptor activity(GO:0004996) |
0.0 | 0.7 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
0.0 | 0.3 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
0.0 | 0.6 | GO:0015645 | fatty acid ligase activity(GO:0015645) |
0.0 | 2.7 | GO:0031072 | heat shock protein binding(GO:0031072) |
0.0 | 1.7 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
0.0 | 0.6 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
0.0 | 0.1 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.0 | 0.2 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
0.0 | 0.2 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
0.0 | 0.3 | GO:0019841 | retinol binding(GO:0019841) |
0.0 | 0.3 | GO:0003840 | gamma-glutamyltransferase activity(GO:0003840) |
0.0 | 0.2 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
0.0 | 3.3 | GO:0004866 | endopeptidase inhibitor activity(GO:0004866) |
0.0 | 0.8 | GO:0005044 | scavenger receptor activity(GO:0005044) |
0.0 | 1.8 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.0 | 8.0 | GO:0003779 | actin binding(GO:0003779) |
0.0 | 0.1 | GO:0004995 | tachykinin receptor activity(GO:0004995) |
0.0 | 0.1 | GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308) |
0.0 | 0.2 | GO:0050780 | dopamine receptor binding(GO:0050780) |
0.0 | 0.2 | GO:0001619 | obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619) |
0.0 | 1.5 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.0 | 1.9 | GO:0003774 | motor activity(GO:0003774) |
0.0 | 0.1 | GO:0005110 | frizzled-2 binding(GO:0005110) |
0.0 | 1.3 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
0.0 | 1.2 | GO:0016462 | pyrophosphatase activity(GO:0016462) |
0.0 | 0.2 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
0.0 | 0.8 | GO:0005178 | integrin binding(GO:0005178) |
0.0 | 0.1 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
0.0 | 0.1 | GO:0004340 | glucokinase activity(GO:0004340) |
0.0 | 1.0 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.0 | 7.1 | GO:0005509 | calcium ion binding(GO:0005509) |
0.0 | 0.7 | GO:0008080 | N-acetyltransferase activity(GO:0008080) |
0.0 | 0.0 | GO:0047288 | monosialoganglioside sialyltransferase activity(GO:0047288) |
0.0 | 0.1 | GO:0043621 | protein self-association(GO:0043621) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 5.3 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
0.1 | 3.3 | ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY | PI3K Pathway |
0.0 | 2.9 | ST_INTEGRIN_SIGNALING_PATHWAY | Integrin Signaling Pathway |
0.0 | 0.8 | SA_CASPASE_CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
0.0 | 0.2 | ST_PAC1_RECEPTOR_PATHWAY | PAC1 Receptor Pathway |