Motif ID: HOMEZ
Z-value: 1.756
Transcription factors associated with HOMEZ:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| HOMEZ | ENSG00000215271.6 | HOMEZ |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 5.7 | GO:0042989 | sequestering of actin monomers(GO:0042989) |
| 0.5 | 2.4 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 0.4 | 3.8 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
| 0.3 | 1.0 | GO:0002890 | negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890) |
| 0.3 | 1.3 | GO:0001778 | plasma membrane repair(GO:0001778) |
| 0.2 | 0.7 | GO:0051083 | 'de novo' cotranslational protein folding(GO:0051083) |
| 0.2 | 1.8 | GO:0031444 | slow-twitch skeletal muscle fiber contraction(GO:0031444) |
| 0.2 | 0.6 | GO:0006428 | isoleucyl-tRNA aminoacylation(GO:0006428) |
| 0.2 | 0.8 | GO:0009103 | lipopolysaccharide biosynthetic process(GO:0009103) |
| 0.2 | 0.8 | GO:0042262 | DNA protection(GO:0042262) |
| 0.2 | 0.5 | GO:0032242 | regulation of nucleoside transport(GO:0032242) |
| 0.2 | 1.5 | GO:0043545 | Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189) |
| 0.2 | 0.6 | GO:0010520 | regulation of reciprocal meiotic recombination(GO:0010520) negative regulation of meiotic nuclear division(GO:0045835) regulation of meiosis I(GO:0060631) |
| 0.1 | 1.2 | GO:0002553 | histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553) |
| 0.1 | 0.5 | GO:0033522 | histone H2A ubiquitination(GO:0033522) |
| 0.1 | 0.6 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 0.1 | 1.3 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.1 | 0.7 | GO:0002710 | negative regulation of T cell mediated immunity(GO:0002710) |
| 0.1 | 1.0 | GO:0046835 | carbohydrate phosphorylation(GO:0046835) |
| 0.1 | 0.3 | GO:0042339 | keratan sulfate metabolic process(GO:0042339) |
| 0.1 | 0.7 | GO:0090400 | stress-induced premature senescence(GO:0090400) |
| 0.1 | 0.3 | GO:0009296 | obsolete flagellum assembly(GO:0009296) |
| 0.1 | 0.4 | GO:0051877 | pigment granule aggregation in cell center(GO:0051877) |
| 0.1 | 0.5 | GO:0001514 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
| 0.1 | 1.0 | GO:0051497 | negative regulation of stress fiber assembly(GO:0051497) |
| 0.1 | 0.7 | GO:0010815 | bradykinin catabolic process(GO:0010815) |
| 0.1 | 0.4 | GO:0017055 | negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) |
| 0.1 | 0.4 | GO:0009143 | nucleoside triphosphate catabolic process(GO:0009143) |
| 0.1 | 0.3 | GO:0007079 | mitotic chromosome movement towards spindle pole(GO:0007079) chromosome movement towards spindle pole(GO:0051305) |
| 0.1 | 0.6 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 0.1 | 0.4 | GO:0032070 | regulation of deoxyribonuclease activity(GO:0032070) |
| 0.1 | 0.5 | GO:0015811 | sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811) |
| 0.1 | 0.4 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) |
| 0.1 | 0.2 | GO:0060011 | Sertoli cell proliferation(GO:0060011) |
| 0.1 | 0.2 | GO:0031118 | rRNA pseudouridine synthesis(GO:0031118) |
| 0.1 | 0.7 | GO:0017121 | phospholipid scrambling(GO:0017121) |
| 0.1 | 1.6 | GO:0006349 | regulation of gene expression by genetic imprinting(GO:0006349) |
| 0.1 | 0.7 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
| 0.1 | 0.4 | GO:2000172 | regulation of branching morphogenesis of a nerve(GO:2000172) |
| 0.1 | 0.1 | GO:0048631 | regulation of skeletal muscle tissue growth(GO:0048631) |
| 0.1 | 0.2 | GO:0010430 | ethanol catabolic process(GO:0006068) fatty acid omega-oxidation(GO:0010430) |
| 0.1 | 0.2 | GO:0000491 | small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492) |
| 0.1 | 0.2 | GO:0071679 | commissural neuron axon guidance(GO:0071679) |
| 0.1 | 0.5 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
| 0.1 | 1.5 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
| 0.1 | 0.2 | GO:0032506 | cytokinetic process(GO:0032506) |
| 0.1 | 0.8 | GO:0006449 | regulation of translational termination(GO:0006449) |
| 0.1 | 0.2 | GO:0009405 | pathogenesis(GO:0009405) |
| 0.1 | 0.3 | GO:0006069 | ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069) |
| 0.0 | 0.1 | GO:0006288 | base-excision repair, DNA ligation(GO:0006288) |
| 0.0 | 0.2 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
| 0.0 | 0.3 | GO:0046541 | saliva secretion(GO:0046541) |
| 0.0 | 0.2 | GO:1901984 | negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757) |
| 0.0 | 0.3 | GO:0042769 | DNA damage response, detection of DNA damage(GO:0042769) |
| 0.0 | 0.3 | GO:0051383 | kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383) |
| 0.0 | 0.1 | GO:0090467 | positive regulation of dendritic cell antigen processing and presentation(GO:0002606) L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023) |
| 0.0 | 0.7 | GO:0051927 | obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927) |
| 0.0 | 0.2 | GO:0006542 | glutamine biosynthetic process(GO:0006542) |
| 0.0 | 0.3 | GO:0042435 | indole-containing compound biosynthetic process(GO:0042435) |
| 0.0 | 0.7 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
| 0.0 | 0.5 | GO:0009629 | response to gravity(GO:0009629) |
| 0.0 | 0.1 | GO:0006530 | asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345) |
| 0.0 | 0.3 | GO:0006072 | glycerol-3-phosphate metabolic process(GO:0006072) |
| 0.0 | 0.1 | GO:1901522 | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522) |
| 0.0 | 0.8 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
| 0.0 | 1.1 | GO:0007263 | nitric oxide mediated signal transduction(GO:0007263) |
| 0.0 | 0.5 | GO:0000301 | retrograde transport, vesicle recycling within Golgi(GO:0000301) |
| 0.0 | 0.6 | GO:0051568 | histone H3-K4 methylation(GO:0051568) |
| 0.0 | 1.3 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.0 | 0.1 | GO:0034723 | DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.0 | 0.2 | GO:0009136 | ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188) |
| 0.0 | 0.3 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.0 | 3.1 | GO:0046330 | positive regulation of JNK cascade(GO:0046330) |
| 0.0 | 1.1 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.0 | 2.2 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.0 | 0.1 | GO:0060279 | progesterone secretion(GO:0042701) regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279) |
| 0.0 | 1.9 | GO:0030833 | regulation of actin filament polymerization(GO:0030833) |
| 0.0 | 0.2 | GO:0015705 | iodide transport(GO:0015705) |
| 0.0 | 0.8 | GO:0000060 | protein import into nucleus, translocation(GO:0000060) |
| 0.0 | 0.6 | GO:0006493 | protein O-linked glycosylation(GO:0006493) |
| 0.0 | 0.9 | GO:0060338 | regulation of type I interferon-mediated signaling pathway(GO:0060338) |
| 0.0 | 0.2 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.0 | 0.1 | GO:0001732 | formation of cytoplasmic translation initiation complex(GO:0001732) cytoplasmic translation(GO:0002181) cytoplasmic translational initiation(GO:0002183) |
| 0.0 | 0.7 | GO:0050909 | sensory perception of taste(GO:0050909) |
| 0.0 | 0.3 | GO:0050872 | white fat cell differentiation(GO:0050872) |
| 0.0 | 0.4 | GO:0042359 | vitamin D metabolic process(GO:0042359) |
| 0.0 | 0.2 | GO:0045542 | positive regulation of cholesterol biosynthetic process(GO:0045542) |
| 0.0 | 0.1 | GO:0046477 | glycosylceramide catabolic process(GO:0046477) |
| 0.0 | 0.5 | GO:0042531 | positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531) |
| 0.0 | 0.3 | GO:0030252 | growth hormone secretion(GO:0030252) |
| 0.0 | 0.1 | GO:0048147 | negative regulation of fibroblast proliferation(GO:0048147) |
| 0.0 | 0.1 | GO:0032465 | regulation of cytokinesis(GO:0032465) |
| 0.0 | 0.5 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
| 0.0 | 0.1 | GO:0001831 | trophectodermal cellular morphogenesis(GO:0001831) |
| 0.0 | 0.3 | GO:0050812 | acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812) |
| 0.0 | 0.2 | GO:0008212 | mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212) |
| 0.0 | 0.1 | GO:0060218 | hematopoietic stem cell differentiation(GO:0060218) |
| 0.0 | 0.5 | GO:0043124 | negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124) |
| 0.0 | 0.2 | GO:0006400 | tRNA modification(GO:0006400) |
| 0.0 | 0.3 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
| 0.0 | 0.2 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
| 0.0 | 0.2 | GO:0003407 | neural retina development(GO:0003407) |
| 0.0 | 0.2 | GO:0006304 | DNA modification(GO:0006304) |
| 0.0 | 0.5 | GO:0036260 | 7-methylguanosine mRNA capping(GO:0006370) 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260) |
| 0.0 | 0.3 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.0 | 0.1 | GO:0034643 | establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) |
| 0.0 | 0.9 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
| 0.0 | 0.3 | GO:0017158 | regulation of calcium ion-dependent exocytosis(GO:0017158) |
| 0.0 | 0.2 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 0.0 | 0.5 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.0 | 0.3 | GO:0046677 | response to antibiotic(GO:0046677) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.2 | GO:0019008 | molybdopterin synthase complex(GO:0019008) |
| 0.2 | 0.6 | GO:0032302 | MutSbeta complex(GO:0032302) |
| 0.2 | 1.1 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.1 | 1.1 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.1 | 1.5 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.1 | 1.3 | GO:0098647 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.1 | 0.4 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
| 0.1 | 0.5 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 0.1 | 0.6 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.1 | 0.8 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.1 | 1.3 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.1 | 0.2 | GO:0005956 | protein kinase CK2 complex(GO:0005956) |
| 0.1 | 0.2 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
| 0.1 | 1.8 | GO:0005861 | troponin complex(GO:0005861) |
| 0.1 | 0.2 | GO:0000153 | cytoplasmic ubiquitin ligase complex(GO:0000153) |
| 0.1 | 0.6 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.1 | 0.1 | GO:0070820 | tertiary granule(GO:0070820) |
| 0.1 | 1.3 | GO:0097525 | spliceosomal snRNP complex(GO:0097525) |
| 0.1 | 0.2 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.1 | 0.6 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.1 | 0.3 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 0.1 | 0.3 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 0.0 | 0.9 | GO:0042581 | specific granule(GO:0042581) |
| 0.0 | 0.4 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.0 | 0.3 | GO:0031512 | motile primary cilium(GO:0031512) |
| 0.0 | 0.1 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.0 | 0.2 | GO:0031205 | endoplasmic reticulum Sec complex(GO:0031205) |
| 0.0 | 3.0 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.0 | 0.4 | GO:0034464 | BBSome(GO:0034464) |
| 0.0 | 0.5 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.0 | 0.3 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.0 | 0.4 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 0.0 | 0.4 | GO:0005678 | obsolete chromatin assembly complex(GO:0005678) |
| 0.0 | 0.4 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 0.0 | 0.4 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 0.0 | 0.2 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
| 0.0 | 0.4 | GO:0071203 | F-actin capping protein complex(GO:0008290) WASH complex(GO:0071203) |
| 0.0 | 0.2 | GO:0070761 | pre-snoRNP complex(GO:0070761) |
| 0.0 | 0.5 | GO:0031264 | death-inducing signaling complex(GO:0031264) |
| 0.0 | 0.3 | GO:0032039 | integrator complex(GO:0032039) |
| 0.0 | 0.8 | GO:0036064 | ciliary basal body(GO:0036064) |
| 0.0 | 0.4 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
| 0.0 | 0.1 | GO:0043512 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
| 0.0 | 2.3 | GO:0044853 | caveola(GO:0005901) plasma membrane raft(GO:0044853) |
| 0.0 | 0.3 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.0 | 2.3 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 0.2 | GO:0030868 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
| 0.0 | 0.7 | GO:0005776 | autophagosome(GO:0005776) |
| 0.0 | 0.5 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.0 | 0.2 | GO:0000796 | condensin complex(GO:0000796) |
| 0.0 | 0.4 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.0 | 0.2 | GO:0000275 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) |
| 0.0 | 0.4 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.0 | 1.3 | GO:0031902 | late endosome membrane(GO:0031902) |
| 0.0 | 0.2 | GO:0045335 | phagocytic vesicle(GO:0045335) |
| 0.0 | 0.2 | GO:0005732 | small nucleolar ribonucleoprotein complex(GO:0005732) |
| 0.0 | 1.6 | GO:0070160 | bicellular tight junction(GO:0005923) occluding junction(GO:0070160) |
| 0.0 | 0.5 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 0.9 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.0 | 0.1 | GO:0005602 | complement component C1 complex(GO:0005602) |
| 0.0 | 0.1 | GO:0005827 | polar microtubule(GO:0005827) |
| 0.0 | 0.1 | GO:0005883 | neurofilament(GO:0005883) |
| 0.0 | 0.4 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 0.6 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 2.1 | GO:0008112 | nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760) |
| 0.3 | 1.2 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 0.3 | 0.8 | GO:0030611 | arsenate reductase activity(GO:0030611) |
| 0.2 | 0.7 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.2 | 0.7 | GO:0033858 | N-acetylgalactosamine kinase activity(GO:0033858) |
| 0.2 | 0.6 | GO:0004822 | isoleucine-tRNA ligase activity(GO:0004822) |
| 0.2 | 0.6 | GO:0000404 | heteroduplex DNA loop binding(GO:0000404) double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181) |
| 0.2 | 3.8 | GO:0042974 | retinoic acid receptor binding(GO:0042974) |
| 0.2 | 0.5 | GO:0002114 | interleukin-33 receptor activity(GO:0002114) |
| 0.1 | 0.4 | GO:0031177 | phosphopantetheine binding(GO:0031177) |
| 0.1 | 0.7 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
| 0.1 | 1.8 | GO:0031014 | troponin T binding(GO:0031014) |
| 0.1 | 0.4 | GO:0008670 | 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670) |
| 0.1 | 0.4 | GO:0004609 | phosphatidylserine decarboxylase activity(GO:0004609) |
| 0.1 | 0.2 | GO:0032139 | dinucleotide insertion or deletion binding(GO:0032139) |
| 0.1 | 1.1 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.1 | 1.5 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 0.1 | 3.2 | GO:0070888 | E-box binding(GO:0070888) |
| 0.1 | 0.3 | GO:0043199 | sulfate binding(GO:0043199) |
| 0.1 | 0.4 | GO:0070643 | vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643) |
| 0.1 | 0.7 | GO:0005132 | type I interferon receptor binding(GO:0005132) |
| 0.1 | 0.5 | GO:0004024 | alcohol dehydrogenase activity, zinc-dependent(GO:0004024) |
| 0.1 | 0.3 | GO:0046403 | polynucleotide 3'-phosphatase activity(GO:0046403) |
| 0.1 | 0.4 | GO:0019103 | pyrimidine nucleotide binding(GO:0019103) |
| 0.1 | 0.3 | GO:0047708 | biotinidase activity(GO:0047708) |
| 0.1 | 0.3 | GO:0043515 | kinetochore binding(GO:0043515) |
| 0.1 | 0.4 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
| 0.1 | 0.5 | GO:0015174 | basic amino acid transmembrane transporter activity(GO:0015174) L-cystine transmembrane transporter activity(GO:0015184) |
| 0.1 | 0.6 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.1 | 0.4 | GO:0060961 | phospholipase D inhibitor activity(GO:0060961) |
| 0.1 | 0.8 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.1 | 0.4 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 0.1 | 2.3 | GO:0008656 | cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) |
| 0.1 | 0.3 | GO:0052590 | sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591) |
| 0.1 | 0.7 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 0.1 | 0.2 | GO:0005224 | ATP-binding and phosphorylation-dependent chloride channel activity(GO:0005224) channel-conductance-controlling ATPase activity(GO:0005260) |
| 0.1 | 0.3 | GO:0030197 | extracellular matrix constituent, lubricant activity(GO:0030197) |
| 0.1 | 1.4 | GO:0017069 | snRNA binding(GO:0017069) |
| 0.1 | 0.9 | GO:0016783 | sulfurtransferase activity(GO:0016783) |
| 0.1 | 0.7 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.1 | 1.1 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 0.1 | 0.4 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.1 | 1.0 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.1 | 0.3 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
| 0.1 | 0.7 | GO:0008527 | taste receptor activity(GO:0008527) |
| 0.1 | 0.2 | GO:0042808 | obsolete neuronal Cdc2-like kinase binding(GO:0042808) |
| 0.1 | 0.7 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.1 | 1.1 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
| 0.1 | 0.3 | GO:0004692 | cGMP-dependent protein kinase activity(GO:0004692) |
| 0.1 | 0.8 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
| 0.1 | 0.3 | GO:0004741 | magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
| 0.1 | 0.2 | GO:0004769 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) steroid delta-isomerase activity(GO:0004769) |
| 0.0 | 0.5 | GO:0070513 | death domain binding(GO:0070513) |
| 0.0 | 0.3 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) |
| 0.0 | 0.3 | GO:0016681 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.0 | 0.1 | GO:0031013 | troponin I binding(GO:0031013) |
| 0.0 | 0.4 | GO:0015385 | sodium:proton antiporter activity(GO:0015385) |
| 0.0 | 0.2 | GO:0016211 | glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880) |
| 0.0 | 0.5 | GO:0004062 | aryl sulfotransferase activity(GO:0004062) |
| 0.0 | 0.2 | GO:0030911 | TPR domain binding(GO:0030911) |
| 0.0 | 0.2 | GO:0004882 | androgen receptor activity(GO:0004882) |
| 0.0 | 0.4 | GO:0051635 | obsolete bacterial cell surface binding(GO:0051635) |
| 0.0 | 1.6 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 0.1 | GO:0005223 | intracellular cGMP activated cation channel activity(GO:0005223) |
| 0.0 | 0.7 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.0 | 0.2 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
| 0.0 | 1.3 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.0 | 1.0 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 0.1 | GO:0004083 | bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619) |
| 0.0 | 0.2 | GO:0016714 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714) |
| 0.0 | 0.4 | GO:0016986 | obsolete transcription initiation factor activity(GO:0016986) |
| 0.0 | 0.1 | GO:0048184 | obsolete follistatin binding(GO:0048184) |
| 0.0 | 0.4 | GO:0005537 | mannose binding(GO:0005537) |
| 0.0 | 0.1 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
| 0.0 | 0.2 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.0 | 0.7 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.0 | 0.3 | GO:0070566 | adenylyltransferase activity(GO:0070566) |
| 0.0 | 0.2 | GO:0030515 | snoRNA binding(GO:0030515) |
| 0.0 | 0.2 | GO:0004522 | ribonuclease A activity(GO:0004522) |
| 0.0 | 0.2 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.0 | 0.6 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 0.1 | GO:0045545 | syndecan binding(GO:0045545) |
| 0.0 | 0.9 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.0 | 0.1 | GO:0015925 | galactosidase activity(GO:0015925) |
| 0.0 | 0.1 | GO:0017096 | acetylserotonin O-methyltransferase activity(GO:0017096) |
| 0.0 | 0.4 | GO:0043022 | ribosome binding(GO:0043022) |
| 0.0 | 0.3 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
| 0.0 | 0.2 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.0 | 0.2 | GO:0008175 | tRNA methyltransferase activity(GO:0008175) |
| 0.0 | 0.1 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
| 0.0 | 0.1 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.0 | 8.1 | GO:0003779 | actin binding(GO:0003779) |
| 0.0 | 0.0 | GO:0008431 | vitamin E binding(GO:0008431) |
| 0.0 | 0.3 | GO:0043531 | ADP binding(GO:0043531) |
| 0.0 | 0.4 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.0 | 0.1 | GO:0015299 | solute:proton antiporter activity(GO:0015299) |
| 0.0 | 0.2 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.0 | 0.9 | GO:0004221 | obsolete ubiquitin thiolesterase activity(GO:0004221) |
| 0.0 | 0.4 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.0 | 0.3 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.0 | 0.4 | GO:0008378 | galactosyltransferase activity(GO:0008378) |
| 0.0 | 0.6 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062) |
| 0.0 | 1.3 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.0 | 0.0 | GO:0004738 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739) |
| 0.0 | 0.4 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 3.5 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.0 | 0.3 | GO:0019003 | GDP binding(GO:0019003) |
| 0.0 | 0.1 | GO:0042166 | acetylcholine binding(GO:0042166) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.1 | ST_ADRENERGIC | Adrenergic Pathway |
| 0.0 | 0.9 | ST_INTERLEUKIN_4_PATHWAY | Interleukin 4 (IL-4) Pathway |
| 0.0 | 0.4 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
