Motif ID: HOXA6
Z-value: 1.201
Transcription factors associated with HOXA6:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| HOXA6 | ENSG00000106006.6 | HOXA6 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 2.0 | GO:0060025 | regulation of synaptic activity(GO:0060025) |
| 0.5 | 1.5 | GO:0007412 | axon target recognition(GO:0007412) |
| 0.4 | 1.1 | GO:2000121 | regulation of removal of superoxide radicals(GO:2000121) |
| 0.3 | 3.6 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.3 | 2.6 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
| 0.2 | 1.9 | GO:0071692 | sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116) |
| 0.2 | 0.8 | GO:0009956 | radial pattern formation(GO:0009956) |
| 0.2 | 1.1 | GO:0035630 | glycolate metabolic process(GO:0009441) bone mineralization involved in bone maturation(GO:0035630) |
| 0.2 | 2.3 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.1 | 1.1 | GO:0060325 | face morphogenesis(GO:0060325) |
| 0.1 | 0.9 | GO:0021830 | interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936) |
| 0.1 | 2.8 | GO:0021846 | cell proliferation in forebrain(GO:0021846) |
| 0.1 | 0.3 | GO:0090047 | obsolete positive regulation of transcription regulator activity(GO:0090047) |
| 0.1 | 4.1 | GO:0050931 | melanocyte differentiation(GO:0030318) pigment cell differentiation(GO:0050931) |
| 0.1 | 0.8 | GO:0007351 | tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595) |
| 0.1 | 9.9 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
| 0.1 | 0.4 | GO:0060259 | regulation of feeding behavior(GO:0060259) |
| 0.1 | 0.3 | GO:0042320 | regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) |
| 0.1 | 0.2 | GO:0048496 | maintenance of organ identity(GO:0048496) |
| 0.1 | 0.2 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) |
| 0.0 | 0.5 | GO:0060216 | definitive hemopoiesis(GO:0060216) |
| 0.0 | 0.2 | GO:0016080 | synaptic vesicle targeting(GO:0016080) |
| 0.0 | 0.1 | GO:0035283 | central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284) |
| 0.0 | 3.1 | GO:0006338 | chromatin remodeling(GO:0006338) |
| 0.0 | 0.2 | GO:0060992 | response to fungicide(GO:0060992) |
| 0.0 | 0.1 | GO:0015722 | canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) |
| 0.0 | 0.2 | GO:0048853 | forebrain morphogenesis(GO:0048853) |
| 0.0 | 0.2 | GO:0010523 | negative regulation of calcium ion transport into cytosol(GO:0010523) |
| 0.0 | 0.6 | GO:0045446 | endothelial cell differentiation(GO:0045446) |
| 0.0 | 0.2 | GO:0060666 | dichotomous subdivision of an epithelial terminal unit(GO:0060600) dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666) |
| 0.0 | 0.7 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.0 | 0.8 | GO:0051101 | regulation of DNA binding(GO:0051101) |
| 0.0 | 1.9 | GO:0008016 | regulation of heart contraction(GO:0008016) |
| 0.0 | 0.1 | GO:0055062 | phosphate ion homeostasis(GO:0055062) divalent inorganic anion homeostasis(GO:0072505) trivalent inorganic anion homeostasis(GO:0072506) |
| 0.0 | 0.3 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
| 0.0 | 0.3 | GO:0019933 | cAMP-mediated signaling(GO:0019933) |
| 0.0 | 0.3 | GO:0009954 | proximal/distal pattern formation(GO:0009954) |
| 0.0 | 0.1 | GO:0051927 | obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.1 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.3 | 3.6 | GO:0098647 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.2 | 3.1 | GO:0071778 | obsolete WINAC complex(GO:0071778) |
| 0.1 | 1.1 | GO:0016942 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) |
| 0.1 | 0.5 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.1 | 2.3 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 0.2 | GO:0060171 | stereocilium membrane(GO:0060171) |
| 0.0 | 2.6 | GO:0000123 | histone acetyltransferase complex(GO:0000123) protein acetyltransferase complex(GO:0031248) acetyltransferase complex(GO:1902493) |
| 0.0 | 8.5 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 0.3 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
| 0.0 | 0.2 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.0 | 0.2 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
| 0.0 | 2.0 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 0.4 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 0.7 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.0 | 0.3 | GO:0032589 | neuron projection membrane(GO:0032589) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 9.9 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093) |
| 0.4 | 1.1 | GO:0005017 | platelet-derived growth factor-activated receptor activity(GO:0005017) |
| 0.3 | 1.5 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
| 0.1 | 3.6 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.1 | 0.5 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.1 | 0.3 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.1 | 0.8 | GO:0003706 | obsolete ligand-regulated transcription factor activity(GO:0003706) |
| 0.1 | 0.2 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) glycine:sodium symporter activity(GO:0015375) |
| 0.1 | 0.5 | GO:0005237 | inhibitory extracellular ligand-gated ion channel activity(GO:0005237) |
| 0.1 | 1.8 | GO:0005024 | transforming growth factor beta-activated receptor activity(GO:0005024) |
| 0.1 | 2.3 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.0 | 0.2 | GO:0005148 | prolactin receptor binding(GO:0005148) |
| 0.0 | 2.8 | GO:0046332 | SMAD binding(GO:0046332) |
| 0.0 | 0.2 | GO:0004517 | nitric-oxide synthase activity(GO:0004517) |
| 0.0 | 0.3 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.0 | 0.2 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.0 | 0.2 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.0 | 0.3 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.0 | 0.2 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
| 0.0 | 0.1 | GO:0015254 | glycerol channel activity(GO:0015254) |
| 0.0 | 0.2 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
| 0.0 | 0.5 | GO:0030346 | protein phosphatase 2B binding(GO:0030346) |
| 0.0 | 3.2 | GO:0008094 | DNA-dependent ATPase activity(GO:0008094) |
| 0.0 | 1.1 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.0 | 0.8 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.0 | 0.2 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
| 0.0 | 3.9 | GO:0003702 | obsolete RNA polymerase II transcription factor activity(GO:0003702) |
| 0.0 | 0.1 | GO:0050682 | AF-2 domain binding(GO:0050682) |
| 0.0 | 0.3 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.0 | 0.1 | GO:0019966 | interleukin-1 binding(GO:0019966) |
| 0.0 | 0.3 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.0 | 0.4 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.0 | 0.1 | GO:0015321 | sodium-dependent phosphate transmembrane transporter activity(GO:0015321) |
| 0.0 | 0.0 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
