Motif ID: HOXB2_UNCX_HOXD3

Z-value: 1.203

Transcription factors associated with HOXB2_UNCX_HOXD3:

Gene SymbolEntrez IDGene Name
HOXB2 ENSG00000173917.9 HOXB2
HOXD3 ENSG00000128652.7 HOXD3
UNCX ENSG00000164853.8 UNCX






Network of associatons between targets according to the STRING database.



First level regulatory network of HOXB2_UNCX_HOXD3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_32908792 3.061 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr21_-_15918618 2.740 ENST00000400564.1
ENST00000400566.1
SAMSN1

SAM domain, SH3 domain and nuclear localization signals 1

chr4_+_40198527 2.546 ENST00000381799.5
RHOH
ras homolog family member H
chr3_-_141747950 2.528 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr10_+_94451574 2.261 ENST00000492654.2
HHEX
hematopoietically expressed homeobox
chr15_-_55562479 2.203 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr13_-_46716969 2.127 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr14_-_106926724 2.109 ENST00000434710.1
IGHV3-43
immunoglobulin heavy variable 3-43
chr16_+_12059091 2.089 ENST00000562385.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr15_-_55562582 1.931 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr6_-_32157947 1.911 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr11_-_33913708 1.900 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr15_-_55563072 1.851 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A


RAB27A, member RAS oncogene family


chr18_+_32556892 1.840 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
MAPRE2



microtubule-associated protein, RP/EB family, member 2



chr2_-_158300556 1.810 ENST00000264192.3
CYTIP
cytohesin 1 interacting protein
chr6_+_13272904 1.792 ENST00000379335.3
ENST00000379329.1
PHACTR1

phosphatase and actin regulator 1

chr16_+_12059050 1.697 ENST00000396495.3
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr13_-_41593425 1.581 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr15_-_37393406 1.547 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2


Meis homeobox 2


chr4_-_105416039 1.522 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr2_-_214016314 1.491 ENST00000434687.1
ENST00000374319.4
IKZF2

IKAROS family zinc finger 2 (Helios)

chr6_+_32407619 1.399 ENST00000395388.2
ENST00000374982.5
HLA-DRA

major histocompatibility complex, class II, DR alpha

chr2_-_216946500 1.395 ENST00000265322.7
PECR
peroxisomal trans-2-enoyl-CoA reductase
chr14_-_106692191 1.343 ENST00000390607.2
IGHV3-21
immunoglobulin heavy variable 3-21
chr3_+_173116225 1.304 ENST00000457714.1
NLGN1
neuroligin 1
chr8_+_50824233 1.297 ENST00000522124.1
SNTG1
syntrophin, gamma 1
chr7_+_138145076 1.231 ENST00000343526.4
TRIM24
tripartite motif containing 24
chr1_-_150738261 1.167 ENST00000448301.2
ENST00000368985.3
CTSS

cathepsin S

chr2_+_196313239 1.145 ENST00000413290.1
AC064834.1
AC064834.1
chr12_-_6233828 1.139 ENST00000572068.1
ENST00000261405.5
VWF

von Willebrand factor

chr6_-_32908765 1.125 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr12_-_15103621 1.122 ENST00000536592.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr14_+_39583427 1.114 ENST00000308317.6
ENST00000396249.2
ENST00000250379.8
ENST00000534684.2
ENST00000527381.1
GEMIN2




gem (nuclear organelle) associated protein 2




chr12_-_25055177 1.102 ENST00000538118.1
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr2_-_61697862 1.092 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr8_+_28748765 1.089 ENST00000355231.5
HMBOX1
homeobox containing 1
chr17_-_62097927 1.081 ENST00000578313.1
ENST00000584084.1
ENST00000579788.1
ENST00000579687.1
ENST00000578379.1
ENST00000578892.1
ENST00000412356.1
ENST00000418105.1
ICAM2







intercellular adhesion molecule 2







chr1_+_198608146 1.080 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
PTPRC









protein tyrosine phosphatase, receptor type, C









chr6_+_26199737 1.073 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chr17_-_62097904 1.071 ENST00000583366.1
ICAM2
intercellular adhesion molecule 2
chr11_-_72070206 1.060 ENST00000544382.1
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr10_+_35484793 0.999 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM




cAMP responsive element modulator




chr1_+_70876926 0.990 ENST00000370938.3
ENST00000346806.2
CTH

cystathionase (cystathionine gamma-lyase)

chr11_-_5255861 0.977 ENST00000380299.3
HBD
hemoglobin, delta
chr6_-_26235206 0.969 ENST00000244534.5
HIST1H1D
histone cluster 1, H1d
chr16_+_33605231 0.964 ENST00000570121.2
IGHV3OR16-12
immunoglobulin heavy variable 3/OR16-12 (non-functional)
chr7_-_25268104 0.962 ENST00000222674.2
NPVF
neuropeptide VF precursor
chr12_-_22063787 0.962 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr10_-_69597810 0.959 ENST00000483798.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr7_+_77428066 0.946 ENST00000422959.2
ENST00000307305.8
ENST00000424760.1
PHTF2


putative homeodomain transcription factor 2


chr1_+_111415757 0.943 ENST00000429072.2
ENST00000271324.5
CD53

CD53 molecule

chr8_-_101571964 0.934 ENST00000520552.1
ENST00000521345.1
ENST00000523000.1
ENST00000335659.3
ENST00000358990.3
ENST00000519597.1
ANKRD46





ankyrin repeat domain 46





chr3_+_178276488 0.929 ENST00000432997.1
ENST00000455865.1
KCNMB2

potassium large conductance calcium-activated channel, subfamily M, beta member 2

chr11_+_59824060 0.925 ENST00000395032.2
ENST00000358152.2
MS4A3

membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)

chrX_-_118986911 0.918 ENST00000276201.2
ENST00000345865.2
UPF3B

UPF3 regulator of nonsense transcripts homolog B (yeast)

chr2_-_89340242 0.917 ENST00000480492.1
IGKV1-12
immunoglobulin kappa variable 1-12
chr1_+_174844645 0.887 ENST00000486220.1
RABGAP1L
RAB GTPase activating protein 1-like
chr13_-_36788718 0.875 ENST00000317764.6
ENST00000379881.3
SOHLH2

spermatogenesis and oogenesis specific basic helix-loop-helix 2

chr8_-_90996459 0.873 ENST00000517337.1
ENST00000409330.1
NBN

nibrin

chr5_+_89770696 0.850 ENST00000504930.1
ENST00000514483.1
POLR3G

polymerase (RNA) III (DNA directed) polypeptide G (32kD)

chr1_-_190446759 0.850 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr19_-_17516449 0.841 ENST00000252593.6
BST2
bone marrow stromal cell antigen 2
chr11_+_7618413 0.824 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr6_+_6588316 0.822 ENST00000379953.2
LY86
lymphocyte antigen 86
chr22_+_23248512 0.819 ENST00000390325.2
IGLC3
immunoglobulin lambda constant 3 (Kern-Oz+ marker)
chr1_+_70876891 0.802 ENST00000411986.2
CTH
cystathionase (cystathionine gamma-lyase)
chr11_+_59824127 0.791 ENST00000278865.3
MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr11_+_22696314 0.784 ENST00000532398.1
ENST00000433790.1
GAS2

growth arrest-specific 2

chr14_+_21249200 0.782 ENST00000304677.2
RNASE6
ribonuclease, RNase A family, k6
chr7_+_150065278 0.780 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
REPIN1


replication initiator 1


chr7_+_77428149 0.775 ENST00000415251.2
ENST00000275575.7
PHTF2

putative homeodomain transcription factor 2

chr16_-_29910853 0.762 ENST00000308713.5
SEZ6L2
seizure related 6 homolog (mouse)-like 2
chr10_-_69597915 0.760 ENST00000225171.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr14_-_20801427 0.753 ENST00000557665.1
ENST00000358932.4
ENST00000353689.4
CCNB1IP1


cyclin B1 interacting protein 1, E3 ubiquitin protein ligase


chr6_+_150920999 0.750 ENST00000367328.1
ENST00000367326.1
PLEKHG1

pleckstrin homology domain containing, family G (with RhoGef domain) member 1

chr5_+_89770664 0.743 ENST00000503973.1
ENST00000399107.1
POLR3G

polymerase (RNA) III (DNA directed) polypeptide G (32kD)

chr6_+_151042224 0.740 ENST00000358517.2
PLEKHG1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr1_-_149783914 0.734 ENST00000369167.1
ENST00000427880.2
ENST00000545683.1
HIST2H2BF


histone cluster 2, H2bf


chr14_-_106668095 0.733 ENST00000390606.2
IGHV3-20
immunoglobulin heavy variable 3-20
chr13_-_47012325 0.729 ENST00000409879.2
KIAA0226L
KIAA0226-like
chr6_-_26032288 0.726 ENST00000244661.2
HIST1H3B
histone cluster 1, H3b
chr12_-_23737534 0.721 ENST00000396007.2
SOX5
SRY (sex determining region Y)-box 5
chrX_-_110655306 0.713 ENST00000371993.2
DCX
doublecortin
chr20_+_30327063 0.707 ENST00000300403.6
ENST00000340513.4
TPX2

TPX2, microtubule-associated

chr8_+_94241867 0.702 ENST00000598428.1
AC016885.1
Uncharacterized protein
chr6_+_31583761 0.692 ENST00000376049.4
AIF1
allograft inflammatory factor 1
chr12_-_112279694 0.691 ENST00000443596.1
ENST00000442119.1
MAPKAPK5-AS1

MAPKAPK5 antisense RNA 1

chr8_-_102803163 0.690 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
NCALD






neurocalcin delta






chr2_-_99279928 0.688 ENST00000414521.2
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr19_-_10446449 0.679 ENST00000592439.1
ICAM3
intercellular adhesion molecule 3
chrX_-_138724994 0.677 ENST00000536274.1
MCF2
MCF.2 cell line derived transforming sequence
chr15_-_20193370 0.670 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr17_-_64225508 0.661 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr18_-_67624160 0.657 ENST00000581982.1
ENST00000280200.4
CD226

CD226 molecule

chr18_-_3220106 0.657 ENST00000356443.4
ENST00000400569.3
MYOM1

myomesin 1

chr15_+_75080883 0.651 ENST00000567571.1
CSK
c-src tyrosine kinase
chr12_-_118628350 0.644 ENST00000537952.1
ENST00000537822.1
TAOK3

TAO kinase 3

chr8_+_28196157 0.644 ENST00000522209.1
PNOC
prepronociceptin
chr2_-_89292422 0.641 ENST00000495489.1
IGKV1-8
immunoglobulin kappa variable 1-8
chr11_+_128563652 0.639 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr12_-_112123524 0.637 ENST00000327551.6
BRAP
BRCA1 associated protein
chr14_-_106552755 0.634 ENST00000390600.2
IGHV3-9
immunoglobulin heavy variable 3-9
chr2_+_90248739 0.632 ENST00000468879.1
IGKV1D-43
immunoglobulin kappa variable 1D-43
chr3_-_33686743 0.628 ENST00000333778.6
ENST00000539981.1
CLASP2

cytoplasmic linker associated protein 2

chr10_+_97515409 0.626 ENST00000371207.3
ENST00000543964.1
ENTPD1

ectonucleoside triphosphate diphosphohydrolase 1

chr16_+_10837643 0.622 ENST00000574334.1
ENST00000283027.5
ENST00000433392.2
NUBP1


nucleotide binding protein 1


chr6_-_39693111 0.618 ENST00000373215.3
ENST00000538893.1
ENST00000287152.7
ENST00000373216.3
KIF6



kinesin family member 6



chr12_+_25205568 0.612 ENST00000548766.1
ENST00000556887.1
LRMP

lymphoid-restricted membrane protein

chr6_-_32498046 0.612 ENST00000374975.3
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr7_+_116660246 0.611 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
ST7





suppression of tumorigenicity 7





chr16_+_31885079 0.608 ENST00000300870.10
ENST00000394846.3
ZNF267

zinc finger protein 267

chr2_+_89184868 0.608 ENST00000390243.2
IGKV4-1
immunoglobulin kappa variable 4-1
chr18_-_3219847 0.608 ENST00000261606.7
MYOM1
myomesin 1
chr6_-_49604545 0.595 ENST00000371175.4
ENST00000229810.7
RHAG

Rh-associated glycoprotein

chrX_+_49294472 0.594 ENST00000361446.5
GAGE12B
G antigen 12B
chr16_+_12058961 0.574 ENST00000053243.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr8_+_38585704 0.574 ENST00000519416.1
ENST00000520615.1
TACC1

transforming, acidic coiled-coil containing protein 1

chr3_+_108541608 0.568 ENST00000426646.1
TRAT1
T cell receptor associated transmembrane adaptor 1
chr9_+_12693336 0.567 ENST00000381137.2
ENST00000388918.5
TYRP1

tyrosinase-related protein 1

chr1_-_160681593 0.564 ENST00000368045.3
ENST00000368046.3
CD48

CD48 molecule

chr15_-_55541227 0.562 ENST00000566877.1
RAB27A
RAB27A, member RAS oncogene family
chr17_-_28618867 0.555 ENST00000394819.3
ENST00000577623.1
BLMH

bleomycin hydrolase

chr7_-_22234381 0.553 ENST00000458533.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr1_+_158801095 0.552 ENST00000368141.4
MNDA
myeloid cell nuclear differentiation antigen
chr10_-_50970322 0.547 ENST00000374103.4
OGDHL
oxoglutarate dehydrogenase-like
chr3_-_108248169 0.544 ENST00000273353.3
MYH15
myosin, heavy chain 15
chr22_+_18632666 0.536 ENST00000215794.7
USP18
ubiquitin specific peptidase 18
chr1_+_168148169 0.535 ENST00000367833.2
TIPRL
TIP41, TOR signaling pathway regulator-like (S. cerevisiae)
chr16_+_85645007 0.533 ENST00000405402.2
GSE1
Gse1 coiled-coil protein
chr17_-_39191107 0.531 ENST00000344363.5
KRTAP1-3
keratin associated protein 1-3
chr8_-_86253888 0.531 ENST00000522389.1
ENST00000432364.2
ENST00000517618.1
CA1


carbonic anhydrase I


chr6_-_29527702 0.528 ENST00000377050.4
UBD
ubiquitin D
chr1_+_117963209 0.527 ENST00000449370.2
MAN1A2
mannosidase, alpha, class 1A, member 2
chr4_-_84035868 0.525 ENST00000426923.2
ENST00000509973.1
PLAC8

placenta-specific 8

chr5_+_102455968 0.519 ENST00000358359.3
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr3_+_108541545 0.513 ENST00000295756.6
TRAT1
T cell receptor associated transmembrane adaptor 1
chr12_+_51318513 0.512 ENST00000332160.4
METTL7A
methyltransferase like 7A
chr12_-_53601000 0.509 ENST00000338737.4
ENST00000549086.2
ITGB7

integrin, beta 7

chr21_-_43816052 0.505 ENST00000398405.1
TMPRSS3
transmembrane protease, serine 3
chr17_-_56296580 0.505 ENST00000313863.6
ENST00000546108.1
ENST00000337050.7
ENST00000393119.2
MKS1



Meckel syndrome, type 1



chr19_+_1077393 0.504 ENST00000590577.1
HMHA1
histocompatibility (minor) HA-1
chr15_+_81589254 0.501 ENST00000394652.2
IL16
interleukin 16
chr8_-_42234745 0.495 ENST00000220812.2
DKK4
dickkopf WNT signaling pathway inhibitor 4
chr12_-_53601055 0.493 ENST00000552972.1
ENST00000422257.3
ENST00000267082.5
ITGB7


integrin, beta 7


chr11_+_60223225 0.492 ENST00000524807.1
ENST00000345732.4
MS4A1

membrane-spanning 4-domains, subfamily A, member 1

chr17_-_28618948 0.490 ENST00000261714.6
BLMH
bleomycin hydrolase
chr11_-_108093329 0.488 ENST00000278612.8
NPAT
nuclear protein, ataxia-telangiectasia locus
chr4_-_84035905 0.488 ENST00000311507.4
PLAC8
placenta-specific 8
chr16_-_67517716 0.487 ENST00000290953.2
AGRP
agouti related protein homolog (mouse)
chr7_-_87342564 0.487 ENST00000265724.3
ENST00000416177.1
ABCB1

ATP-binding cassette, sub-family B (MDR/TAP), member 1

chr5_-_24645078 0.486 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr10_-_14372870 0.482 ENST00000357447.2
FRMD4A
FERM domain containing 4A
chr8_+_56792355 0.481 ENST00000519728.1
LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr4_-_168155169 0.481 ENST00000534949.1
ENST00000535728.1
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr15_-_65903407 0.475 ENST00000395644.4
ENST00000567744.1
ENST00000568573.1
ENST00000562830.1
ENST00000569491.1
ENST00000561769.1
VWA9





von Willebrand factor A domain containing 9





chr11_+_60223312 0.475 ENST00000532491.1
ENST00000532073.1
ENST00000534668.1
ENST00000528313.1
ENST00000533306.1
MS4A1




membrane-spanning 4-domains, subfamily A, member 1




chr7_+_50348268 0.472 ENST00000438033.1
ENST00000439701.1
IKZF1

IKAROS family zinc finger 1 (Ikaros)

chr6_-_109702885 0.470 ENST00000504373.1
CD164
CD164 molecule, sialomucin
chr1_+_158815588 0.467 ENST00000438394.1
MNDA
myeloid cell nuclear differentiation antigen
chr4_+_38665810 0.457 ENST00000261438.5
ENST00000514033.1
KLF3

Kruppel-like factor 3 (basic)

chr13_+_33160553 0.453 ENST00000315596.10
PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr6_+_153552455 0.452 ENST00000392385.2
AL590867.1
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr3_+_121774202 0.452 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86



CD86 molecule



chr7_-_124569991 0.447 ENST00000446993.1
ENST00000357628.3
ENST00000393329.1
POT1


protection of telomeres 1


chr10_-_72648541 0.445 ENST00000299299.3
PCBD1
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
chr6_+_292051 0.441 ENST00000344450.5
DUSP22
dual specificity phosphatase 22
chr4_-_39979576 0.439 ENST00000303538.8
ENST00000503396.1
PDS5A

PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)

chr2_+_90198535 0.439 ENST00000390276.2
IGKV1D-12
immunoglobulin kappa variable 1D-12
chr11_+_22688150 0.439 ENST00000454584.2
GAS2
growth arrest-specific 2
chr22_-_29107919 0.437 ENST00000434810.1
ENST00000456369.1
CHEK2

checkpoint kinase 2

chr8_-_86290333 0.436 ENST00000521846.1
ENST00000523022.1
ENST00000524324.1
ENST00000519991.1
ENST00000520663.1
ENST00000517590.1
ENST00000522579.1
ENST00000522814.1
ENST00000522662.1
ENST00000523858.1
ENST00000519129.1
CA1










carbonic anhydrase I










chr11_+_102188224 0.435 ENST00000263464.3
BIRC3
baculoviral IAP repeat containing 3
chr2_+_90077680 0.434 ENST00000390270.2
IGKV3D-20
immunoglobulin kappa variable 3D-20
chr1_+_111770278 0.433 ENST00000369748.4
CHI3L2
chitinase 3-like 2
chr4_+_90800656 0.433 ENST00000394980.1
MMRN1
multimerin 1
chr1_+_111770232 0.433 ENST00000369744.2
CHI3L2
chitinase 3-like 2
chr1_+_160709055 0.432 ENST00000368043.3
ENST00000368042.3
ENST00000458602.2
ENST00000458104.2
SLAMF7



SLAM family member 7



chr5_+_156696362 0.430 ENST00000377576.3
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr2_-_136678123 0.430 ENST00000422708.1
DARS
aspartyl-tRNA synthetase
chr12_+_28410128 0.426 ENST00000381259.1
ENST00000381256.1
CCDC91

coiled-coil domain containing 91

chr17_-_29641104 0.425 ENST00000577894.1
ENST00000330927.4
EVI2B

ecotropic viral integration site 2B

chr16_-_30457048 0.425 ENST00000500504.2
ENST00000542752.1
SEPHS2

selenophosphate synthetase 2

chr8_+_56792377 0.425 ENST00000520220.2
LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr1_-_51984908 0.425 ENST00000371730.2
EPS15
epidermal growth factor receptor pathway substrate 15
chr1_+_74701062 0.423 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr12_-_8765446 0.422 ENST00000537228.1
ENST00000229335.6
AICDA

activation-induced cytidine deaminase

chr4_+_147096837 0.418 ENST00000296581.5
ENST00000502781.1
LSM6

LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)

chr17_-_46690839 0.418 ENST00000498634.2
HOXB8
homeobox B8
chrX_-_100604184 0.415 ENST00000372902.3
TIMM8A
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr4_-_155533787 0.415 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
FGG





fibrinogen gamma chain





chr9_+_90112117 0.414 ENST00000358077.5
DAPK1
death-associated protein kinase 1
chr4_+_39460620 0.413 ENST00000340169.2
ENST00000261434.3
LIAS

lipoic acid synthetase

chrX_-_23926004 0.413 ENST00000379226.4
ENST00000379220.3
APOO

apolipoprotein O

chr14_-_107049312 0.412 ENST00000390627.2
IGHV3-53
immunoglobulin heavy variable 3-53
chr2_-_55496344 0.412 ENST00000403721.1
ENST00000263629.4
MTIF2

mitochondrial translational initiation factor 2

chr4_+_39460689 0.411 ENST00000381846.1
LIAS
lipoic acid synthetase
chr7_-_5998714 0.411 ENST00000539903.1
RSPH10B
radial spoke head 10 homolog B (Chlamydomonas)
chr4_+_39460659 0.409 ENST00000513731.1
LIAS
lipoic acid synthetase
chr16_-_21289627 0.406 ENST00000396023.2
ENST00000415987.2
CRYM

crystallin, mu

chr3_-_98241358 0.405 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
CLDND1



claudin domain containing 1




Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 6.5 GO:0043316 natural killer cell activation involved in immune response(GO:0002323) cytotoxic T cell degranulation(GO:0043316) natural killer cell degranulation(GO:0043320)
0.6 2.3 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.5 1.6 GO:0002431 Fc receptor mediated stimulatory signaling pathway(GO:0002431) regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.5 1.6 GO:1901419 regulation of response to alcohol(GO:1901419)
0.4 1.8 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.4 1.2 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.4 1.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.3 1.0 GO:0010107 potassium ion import(GO:0010107)
0.3 1.5 GO:0001832 blastocyst growth(GO:0001832)
0.3 1.5 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.3 6.3 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.2 1.9 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.2 1.4 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.2 0.7 GO:0048496 maintenance of organ identity(GO:0048496)
0.2 1.3 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082)
0.2 0.4 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.2 0.4 GO:0045750 obsolete positive regulation of S phase of mitotic cell cycle(GO:0045750)
0.2 1.4 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857) positive regulation of T cell receptor signaling pathway(GO:0050862)
0.2 1.3 GO:0016584 nucleosome positioning(GO:0016584)
0.2 0.2 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.2 0.9 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.2 0.7 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.2 0.7 GO:0061032 visceral serous pericardium development(GO:0061032)
0.2 0.5 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.2 0.8 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 0.6 GO:0045938 positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.2 0.5 GO:0042097 lymphotoxin A production(GO:0032641) interleukin-4 biosynthetic process(GO:0042097) lymphotoxin A biosynthetic process(GO:0042109) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1 0.4 GO:0006530 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.1 4.4 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.1 1.9 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.5 GO:0070842 aggresome assembly(GO:0070842)
0.1 0.1 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.1 0.5 GO:1904037 positive regulation of epithelial cell apoptotic process(GO:1904037) positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 0.4 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.1 0.4 GO:0051311 meiotic metaphase I plate congression(GO:0043060) spindle midzone assembly(GO:0051255) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.1 0.4 GO:1904358 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.1 0.6 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.8 GO:0051026 chiasma assembly(GO:0051026)
0.1 0.5 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.7 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.7 GO:0019985 translesion synthesis(GO:0019985)
0.1 0.6 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.1 0.9 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 0.3 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.1 0.5 GO:0034616 response to laminar fluid shear stress(GO:0034616)
0.1 0.3 GO:0016926 protein desumoylation(GO:0016926)
0.1 0.3 GO:2000105 positive regulation of DNA-dependent DNA replication initiation(GO:0032298) positive regulation of DNA-dependent DNA replication(GO:2000105)
0.1 0.8 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.3 GO:0014900 smooth muscle hyperplasia(GO:0014806) muscle hyperplasia(GO:0014900) positive regulation of guanylate cyclase activity(GO:0031284)
0.1 0.1 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.5 GO:0060259 regulation of feeding behavior(GO:0060259)
0.1 0.4 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.1 GO:0032754 positive regulation of interleukin-5 production(GO:0032754)
0.1 0.9 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.2 GO:0002326 B cell lineage commitment(GO:0002326)
0.1 0.9 GO:0015074 DNA integration(GO:0015074)
0.1 1.6 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 0.4 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.1 0.2 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537)
0.1 0.3 GO:0010900 regulation of phosphatidylcholine catabolic process(GO:0010899) negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.1 0.3 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 0.1 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.1 0.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.1 2.5 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.1 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.1 0.6 GO:0042448 progesterone metabolic process(GO:0042448)
0.1 0.2 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.1 0.4 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1 0.1 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 0.4 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.8 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.2 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.1 2.5 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 0.2 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1 1.7 GO:0042554 superoxide anion generation(GO:0042554)
0.1 0.3 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 0.3 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.1 0.6 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.8 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 0.2 GO:0010430 ethanol catabolic process(GO:0006068) fatty acid omega-oxidation(GO:0010430)
0.1 0.6 GO:1902622 regulation of neutrophil chemotaxis(GO:0090022) regulation of neutrophil migration(GO:1902622)
0.1 0.1 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.4 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 0.9 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.4 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1 0.2 GO:0060405 regulation of penile erection(GO:0060405)
0.1 1.0 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.1 0.4 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 0.8 GO:0019228 neuronal action potential(GO:0019228)
0.1 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.2 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 0.5 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.1 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.1 0.2 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 0.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.3 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.1 0.2 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1 1.0 GO:0006906 vesicle fusion(GO:0006906)
0.1 0.6 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 0.4 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 0.1 GO:1901798 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.1 1.1 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 0.2 GO:0034126 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) positive regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034126)
0.1 0.2 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.1 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.5 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.0 0.3 GO:0046618 drug export(GO:0046618)
0.0 0.3 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 0.2 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.0 GO:0046101 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0 0.4 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.2 GO:0051852 disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.0 0.5 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.0 0.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.0 GO:0006545 glycine biosynthetic process(GO:0006545)
0.0 0.2 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 1.2 GO:0051225 spindle assembly(GO:0051225)
0.0 0.2 GO:0015793 canalicular bile acid transport(GO:0015722) glycerol transport(GO:0015793) pyrimidine nucleobase transport(GO:0015855)
0.0 0.6 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.8 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.0 0.3 GO:0006553 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.1 GO:0046146 tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.6 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.4 GO:0090399 replicative senescence(GO:0090399)
0.0 0.1 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0 0.2 GO:0035058 nonmotile primary cilium assembly(GO:0035058)
0.0 0.4 GO:0015886 heme transport(GO:0015886)
0.0 0.2 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.4 GO:0007141 male meiosis I(GO:0007141)
0.0 0.2 GO:0030330 DNA damage response, signal transduction by p53 class mediator(GO:0030330)
0.0 0.1 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.1 GO:0002577 regulation of antigen processing and presentation(GO:0002577) positive regulation of antigen processing and presentation(GO:0002579)
0.0 0.3 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.0 0.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.4 GO:0009070 serine family amino acid biosynthetic process(GO:0009070)
0.0 0.1 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.0 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.3 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.9 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.3 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 0.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.4 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.2 GO:0051383 kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383)
0.0 0.5 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.0 0.2 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.3 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.0 0.6 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.1 GO:2000858 renin-angiotensin regulation of aldosterone production(GO:0002018) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) obsolete regulation of natriuresis(GO:0003078) positive regulation of NAD(P)H oxidase activity(GO:0033864) mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) regulation of mineralocorticoid secretion(GO:2000855) regulation of aldosterone secretion(GO:2000858)
0.0 0.0 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.2 GO:0035444 nickel cation transport(GO:0015675) vanadium ion transport(GO:0015676) ferrous iron transport(GO:0015684) lead ion transport(GO:0015692) nickel cation transmembrane transport(GO:0035444) ferrous iron import(GO:0070627) manganese ion transmembrane transport(GO:0071421) iron ion import(GO:0097286)
0.0 0.2 GO:0030903 notochord development(GO:0030903)
0.0 1.0 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:0042391 regulation of membrane potential(GO:0042391)
0.0 0.2 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.3 GO:0006570 tyrosine metabolic process(GO:0006570)
0.0 0.1 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.4 GO:0051592 response to calcium ion(GO:0051592)
0.0 0.2 GO:0030147 obsolete natriuresis(GO:0030147)
0.0 0.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.4 GO:0007498 mesoderm development(GO:0007498)
0.0 0.9 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.2 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.0 0.6 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.2 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.5 GO:0006298 mismatch repair(GO:0006298)
0.0 0.0 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.4 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.1 GO:0016556 base conversion or substitution editing(GO:0016553) mRNA modification(GO:0016556)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.0 0.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.4 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 0.3 GO:0046037 GMP metabolic process(GO:0046037)
0.0 0.4 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.2 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.1 GO:0002687 positive regulation of leukocyte migration(GO:0002687)
0.0 0.4 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.1 GO:0050892 intestinal absorption(GO:0050892)
0.0 1.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 1.4 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.2 GO:0070189 kynurenine metabolic process(GO:0070189)
0.0 0.2 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 0.4 GO:0050812 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.4 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.6 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.2 GO:0033014 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.0 0.1 GO:0032099 negative regulation of appetite(GO:0032099)
0.0 0.1 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.1 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.0 0.2 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.2 GO:0006084 acetyl-CoA metabolic process(GO:0006084)
0.0 2.0 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.4 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.9 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.2 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 1.5 GO:0006401 RNA catabolic process(GO:0006401)
0.0 0.2 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.8 GO:0048477 oogenesis(GO:0048477)
0.0 0.2 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.1 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 3.0 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.1 GO:0032416 negative regulation of ion transmembrane transporter activity(GO:0032413) negative regulation of sodium:proton antiporter activity(GO:0032416) positive regulation of dopamine receptor signaling pathway(GO:0060161) negative regulation of sodium ion transmembrane transport(GO:1902306) negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.0 0.1 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.4 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.0 1.4 GO:0006959 humoral immune response(GO:0006959)
0.0 0.4 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260)
0.0 0.3 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.2 GO:0007320 insemination(GO:0007320)
0.0 0.2 GO:0020027 hemoglobin metabolic process(GO:0020027)
0.0 0.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759) forebrain dorsal/ventral pattern formation(GO:0021798) menarche(GO:0042696)
0.0 0.3 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.7 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.0 0.2 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.1 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.5 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.1 GO:0034614 cellular response to reactive oxygen species(GO:0034614)
0.0 1.1 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.1 GO:0046697 maternal placenta development(GO:0001893) decidualization(GO:0046697)
0.0 0.1 GO:0010870 positive regulation of receptor biosynthetic process(GO:0010870)
0.0 0.1 GO:0032776 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.4 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 0.1 GO:0048661 positive regulation of smooth muscle cell proliferation(GO:0048661)
0.0 0.1 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.0 GO:0021896 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
0.0 0.1 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.3 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.1 GO:0044818 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) mitotic G2/M transition checkpoint(GO:0044818) negative regulation of cell cycle G2/M phase transition(GO:1902750)
0.0 0.0 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.6 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.1 GO:0016180 snRNA processing(GO:0016180)
0.0 0.8 GO:0019233 sensory perception of pain(GO:0019233)
0.0 0.4 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.5 GO:0042384 cilium assembly(GO:0042384)
0.0 0.0 GO:0030035 microspike assembly(GO:0030035)
0.0 0.0 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 0.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998) cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.0 0.0 GO:1901642 purine nucleoside transmembrane transport(GO:0015860) purine-containing compound transmembrane transport(GO:0072530) nucleoside transmembrane transport(GO:1901642)
0.0 0.3 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.4 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.0 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.0 0.8 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.2 GO:0045123 cellular extravasation(GO:0045123)
0.0 0.4 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.4 GO:0042113 B cell activation(GO:0042113)
0.0 0.3 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.0 0.1 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0 0.6 GO:0017156 calcium ion regulated exocytosis(GO:0017156)
0.0 0.1 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.1 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.1 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.3 GO:0019674 NAD metabolic process(GO:0019674)
0.0 0.3 GO:0048709 oligodendrocyte differentiation(GO:0048709)
0.0 0.1 GO:0032649 regulation of interferon-gamma production(GO:0032649) positive regulation of interferon-gamma production(GO:0032729)
0.0 0.2 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
0.0 0.2 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.1 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.5 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.0 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.0 GO:0048262 negative regulation of cell fate commitment(GO:0010454) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898) determination of dorsal/ventral asymmetry(GO:0048262) determination of dorsal identity(GO:0048263)
0.0 0.1 GO:0046827 regulation of protein export from nucleus(GO:0046825) positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.2 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.0 0.0 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.0 GO:0045896 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0 0.1 GO:0007416 synapse assembly(GO:0007416)
0.0 0.0 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.2 GO:0000060 protein import into nucleus, translocation(GO:0000060)
0.0 0.1 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.7 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 0.1 GO:1903307 positive regulation of myeloid leukocyte mediated immunity(GO:0002888) positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306) positive regulation of exocytosis(GO:0045921) positive regulation of regulated secretory pathway(GO:1903307)
0.0 0.2 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.0 0.7 GO:0034339 obsolete regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor(GO:0034339)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.3 1.3 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.3 2.1 GO:0001891 phagocytic cup(GO:0001891)
0.3 6.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 1.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 1.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.2 2.2 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2 1.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.2 0.7 GO:0016600 flotillin complex(GO:0016600)
0.1 0.4 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 1.5 GO:0005884 actin filament(GO:0005884)
0.1 0.9 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 0.3 GO:0005873 plus-end kinesin complex(GO:0005873)
0.1 0.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.3 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 0.1 GO:0045177 apical part of cell(GO:0045177)
0.1 0.9 GO:0070652 HAUS complex(GO:0070652)
0.1 1.1 GO:0030061 mitochondrial crista(GO:0030061)
0.1 0.4 GO:0005712 chiasma(GO:0005712) MutLbeta complex(GO:0032390)
0.1 1.2 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.3 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.1 6.3 GO:0030667 secretory granule membrane(GO:0030667)
0.1 0.9 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.3 GO:0005687 U4 snRNP(GO:0005687)
0.1 0.4 GO:0060171 stereocilium membrane(GO:0060171)
0.1 0.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 0.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.5 GO:0042575 DNA polymerase complex(GO:0042575)
0.1 3.5 GO:0000786 nucleosome(GO:0000786)
0.1 1.1 GO:0032982 myosin filament(GO:0032982)
0.1 0.6 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.8 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 2.8 GO:0032993 protein-DNA complex(GO:0032993)
0.1 0.5 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 1.1 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.3 GO:0010369 chromocenter(GO:0010369)
0.0 0.9 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.4 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 1.5 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.0 GO:0043205 fibril(GO:0043205)
0.0 0.8 GO:0016235 aggresome(GO:0016235)
0.0 0.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 0.3 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.3 GO:0005827 polar microtubule(GO:0005827)
0.0 0.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.6 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.5 GO:0030027 lamellipodium(GO:0030027)
0.0 0.1 GO:0036452 ESCRT III complex(GO:0000815) ESCRT complex(GO:0036452)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 1.8 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.8 GO:0005871 kinesin complex(GO:0005871)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.7 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.3 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.5 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.3 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.1 GO:0000800 lateral element(GO:0000800)
0.0 0.4 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.3 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 0.6 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0042827 platelet dense granule(GO:0042827)
0.0 1.4 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 1.3 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.3 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.4 GO:0015030 Cajal body(GO:0015030)
0.0 0.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.2 GO:0030990 intraciliary transport particle(GO:0030990)
0.0 0.6 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.2 GO:0000125 PCAF complex(GO:0000125)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.2 GO:0045120 pronucleus(GO:0045120)
0.0 0.1 GO:0001741 XY body(GO:0001741)
0.0 0.1 GO:0099738 apical cortex(GO:0045179) cell cortex region(GO:0099738)
0.0 2.5 GO:0005769 early endosome(GO:0005769)
0.0 0.5 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 1.9 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.6 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.4 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.0 GO:0005770 late endosome(GO:0005770)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.1 GO:0032039 integrator complex(GO:0032039)
0.0 0.0 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.1 GO:0030673 axolemma(GO:0030673)
0.0 0.3 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 1.1 GO:0034705 potassium channel complex(GO:0034705)
0.0 1.6 GO:0009897 external side of plasma membrane(GO:0009897)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.2 GO:0031489 myosin V binding(GO:0031489)
0.6 2.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.4 1.2 GO:0070283 lipoate-protein ligase activity(GO:0016979) lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.4 2.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.4 0.8 GO:0016874 ligase activity(GO:0016874)
0.3 1.4 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.3 1.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.3 0.5 GO:0070628 proteasome binding(GO:0070628)
0.2 4.4 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.2 1.3 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 0.8 GO:0008907 integrase activity(GO:0008907)
0.2 0.8 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.2 0.9 GO:0000827 inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.2 0.5 GO:0005174 CD40 receptor binding(GO:0005174)
0.2 1.4 GO:0019826 oxygen sensor activity(GO:0019826)
0.2 0.5 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.7 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.4 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 1.2 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.8 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 1.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.5 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.1 0.7 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 2.7 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.4 GO:0050062 long-chain-fatty-acyl-CoA reductase activity(GO:0050062)
0.1 0.5 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1 0.5 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.7 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 1.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.4 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.1 1.7 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.9 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 0.2 GO:0005310 dicarboxylic acid transmembrane transporter activity(GO:0005310)
0.1 0.3 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 0.5 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700)
0.1 1.5 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.4 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 0.3 GO:0016289 CoA hydrolase activity(GO:0016289)
0.1 0.6 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.6 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.1 0.9 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.6 GO:0030492 hemoglobin binding(GO:0030492)
0.1 0.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.2 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 0.3 GO:0016531 copper chaperone activity(GO:0016531)
0.1 0.6 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.3 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.1 0.4 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 1.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.0 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.2 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.1 0.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.3 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.7 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 0.5 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.1 0.3 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.1 0.4 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.1 0.1 GO:0004518 nuclease activity(GO:0004518)
0.1 0.3 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 0.8 GO:0004568 chitinase activity(GO:0004568)
0.1 0.9 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.5 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.1 0.3 GO:0080030 methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.1 0.2 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.1 0.7 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.2 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
0.1 0.2 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 0.2 GO:0004146 dihydrofolate reductase activity(GO:0004146)
0.1 0.2 GO:0035276 ethanol binding(GO:0035276)
0.1 0.3 GO:0034711 inhibin binding(GO:0034711)
0.1 0.4 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.1 0.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 1.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.2 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.2 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 0.4 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 0.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.2 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.3 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.1 0.2 GO:0043398 HLH domain binding(GO:0043398)
0.1 0.4 GO:0031432 titin binding(GO:0031432)
0.1 0.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.4 GO:0015232 heme transporter activity(GO:0015232)
0.1 1.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.1 GO:0043426 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648) MRF binding(GO:0043426)
0.0 0.7 GO:0030276 clathrin binding(GO:0030276)
0.0 0.4 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.8 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 0.4 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.3 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187) glycine:sodium symporter activity(GO:0015375)
0.0 0.4 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 1.0 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.1 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.0 0.4 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.7 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.2 GO:0034701 tripeptidase activity(GO:0034701)
0.0 0.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.4 GO:0003701 obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0 1.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.4 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.3 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0031493 nucleosomal histone binding(GO:0031493) SAM domain binding(GO:0032093)
0.0 0.4 GO:0031013 troponin I binding(GO:0031013)
0.0 0.3 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 2.3 GO:0003823 antigen binding(GO:0003823)
0.0 0.4 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.4 GO:0060590 ATPase regulator activity(GO:0060590)
0.0 0.3 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.0 2.0 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.5 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 3.5 GO:0008017 microtubule binding(GO:0008017)
0.0 0.2 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093)
0.0 2.2 GO:0004221 obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0 0.2 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 0.1 GO:0005224 ATP-binding and phosphorylation-dependent chloride channel activity(GO:0005224) channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.2 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) ferrous iron transmembrane transporter activity(GO:0015093) lead ion transmembrane transporter activity(GO:0015094) nickel cation transmembrane transporter activity(GO:0015099) vanadium ion transmembrane transporter activity(GO:0015100) chromium ion transmembrane transporter activity(GO:0070835)
0.0 1.6 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.7 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.2 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 2.1 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 2.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0004083 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0 1.0 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 1.4 GO:0050136 NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.7 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.3 GO:0001228 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.2 GO:0051378 serotonin binding(GO:0051378)
0.0 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.2 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.3 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.2 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 1.0 GO:0008009 chemokine activity(GO:0008009)
0.0 2.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0050051 leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.0 0.1 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 1.0 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.4 GO:0043499 obsolete eukaryotic cell surface binding(GO:0043499)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.3 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.1 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.4 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.1 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0 0.1 GO:0097159 organic cyclic compound binding(GO:0097159)
0.0 0.1 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.0 0.1 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.7 GO:0005507 copper ion binding(GO:0005507)
0.0 0.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 1.6 GO:0003704 obsolete specific RNA polymerase II transcription factor activity(GO:0003704)
0.0 0.1 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.2 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.2 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.1 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0004988 obsolete mu-opioid receptor activity(GO:0004988)
0.0 0.0 GO:0004802 transketolase activity(GO:0004802)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.7 GO:0010843 obsolete promoter binding(GO:0010843)
0.0 0.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.0 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.0 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.0 GO:0004946 bombesin receptor activity(GO:0004946)
0.0 0.6 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 1.0 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.2 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 4.1 GO:0008134 transcription factor binding(GO:0008134)
0.0 0.2 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.2 GO:0019239 deaminase activity(GO:0019239)
0.0 0.0 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 3.0 GO:0016563 obsolete transcription activator activity(GO:0016563)
0.0 0.0 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.5 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.2 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.0 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.0 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.6 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.1 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.5 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.1 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.2 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.0 0.3 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.2 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.0 0.5 SIG_CD40PATHWAYMAP Genes related to CD40 signaling