Motif ID: HOXB6_PRRX2

Z-value: 2.691

Transcription factors associated with HOXB6_PRRX2:

Gene SymbolEntrez IDGene Name
HOXB6 ENSG00000108511.8 HOXB6
PRRX2 ENSG00000167157.9 PRRX2






Network of associatons between targets according to the STRING database.



First level regulatory network of HOXB6_PRRX2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_175711133 9.335 ENST00000409597.1
ENST00000413882.1
CHN1

chimerin 1

chr7_-_27205136 9.075 ENST00000396345.1
ENST00000343483.6
HOXA9

homeobox A9

chr12_-_91576561 7.886 ENST00000547568.2
ENST00000552962.1
DCN

decorin

chr12_-_91576750 7.747 ENST00000228329.5
ENST00000303320.3
ENST00000052754.5
DCN


decorin


chr18_-_53089723 7.247 ENST00000561992.1
ENST00000562512.2
TCF4

transcription factor 4

chrX_+_135251783 6.952 ENST00000394153.2
FHL1
four and a half LIM domains 1
chr12_-_91576429 6.835 ENST00000552145.1
ENST00000546745.1
DCN

decorin

chr3_+_159557637 6.705 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr3_-_114477787 6.224 ENST00000464560.1
ZBTB20
zinc finger and BTB domain containing 20
chr3_+_158787041 6.117 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1


IQCJ-SCHIP1 readthrough


chrX_+_135279179 5.822 ENST00000370676.3
FHL1
four and a half LIM domains 1
chr7_+_102553430 5.573 ENST00000339431.4
ENST00000249377.4
LRRC17

leucine rich repeat containing 17

chr3_-_114477962 5.543 ENST00000471418.1
ZBTB20
zinc finger and BTB domain containing 20
chrX_+_135278908 5.050 ENST00000539015.1
ENST00000370683.1
FHL1

four and a half LIM domains 1

chrX_+_135252050 4.959 ENST00000449474.1
ENST00000345434.3
FHL1

four and a half LIM domains 1

chr1_-_68698222 4.924 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS



wntless Wnt ligand secretion mediator



chrX_+_135251835 4.863 ENST00000456445.1
FHL1
four and a half LIM domains 1
chr8_-_122653630 4.764 ENST00000303924.4
HAS2
hyaluronan synthase 2
chr12_+_81110684 4.219 ENST00000228644.3
MYF5
myogenic factor 5
chr4_+_41258786 4.049 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
UCHL1



ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)



chr8_-_18744528 4.045 ENST00000523619.1
PSD3
pleckstrin and Sec7 domain containing 3
chr4_-_111563076 3.951 ENST00000354925.2
ENST00000511990.1
PITX2

paired-like homeodomain 2

chr13_+_76334795 3.791 ENST00000526202.1
ENST00000465261.2
LMO7

LIM domain 7

chr11_-_27723158 3.773 ENST00000395980.2
BDNF
brain-derived neurotrophic factor
chr13_-_38172863 3.687 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
POSTN





periostin, osteoblast specific factor





chr4_+_169418195 3.684 ENST00000261509.6
ENST00000335742.7
PALLD

palladin, cytoskeletal associated protein

chr13_+_76334567 3.633 ENST00000321797.8
LMO7
LIM domain 7
chr4_-_143226979 3.621 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr18_-_52989217 3.593 ENST00000570287.2
TCF4
transcription factor 4
chr17_-_77924627 3.570 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
TBC1D16





TBC1 domain family, member 16





chr10_+_11047259 3.567 ENST00000379261.4
ENST00000416382.2
CELF2

CUGBP, Elav-like family member 2

chr9_-_13165457 3.401 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
MPDZ


multiple PDZ domain protein


chr16_+_7382745 3.319 ENST00000436368.2
ENST00000311745.5
ENST00000355637.4
ENST00000340209.4
RBFOX1



RNA binding protein, fox-1 homolog (C. elegans) 1



chr18_-_52989525 3.227 ENST00000457482.3
TCF4
transcription factor 4
chr11_+_12399071 3.177 ENST00000539723.1
ENST00000550549.1
PARVA

parvin, alpha

chr2_-_190927447 3.160 ENST00000260950.4
MSTN
myostatin
chr7_+_134464376 3.104 ENST00000454108.1
ENST00000361675.2
CALD1

caldesmon 1

chr3_-_55521323 3.087 ENST00000264634.4
WNT5A
wingless-type MMTV integration site family, member 5A
chr2_-_145278475 3.064 ENST00000558170.2
ZEB2
zinc finger E-box binding homeobox 2
chr17_-_46671323 3.054 ENST00000239151.5
HOXB5
homeobox B5
chr17_-_10452929 3.023 ENST00000532183.2
ENST00000397183.2
ENST00000420805.1
MYH2


myosin, heavy chain 2, skeletal muscle, adult


chr1_-_57045228 2.973 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr17_-_46682321 2.935 ENST00000225648.3
ENST00000484302.2
HOXB6

homeobox B6

chr12_-_91539918 2.925 ENST00000548218.1
DCN
decorin
chr12_-_91574142 2.917 ENST00000547937.1
DCN
decorin
chr13_+_102104980 2.888 ENST00000545560.2
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr12_-_91546926 2.829 ENST00000550758.1
DCN
decorin
chr7_-_27183263 2.810 ENST00000222726.3
HOXA5
homeobox A5
chr1_+_84630053 2.776 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
PRKACB


protein kinase, cAMP-dependent, catalytic, beta


chr18_-_21891460 2.756 ENST00000357041.4
OSBPL1A
oxysterol binding protein-like 1A
chr13_+_102104952 2.737 ENST00000376180.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr17_+_42634844 2.723 ENST00000315323.3
FZD2
frizzled family receptor 2
chr2_+_170366203 2.708 ENST00000284669.1
KLHL41
kelch-like family member 41
chr17_-_46688334 2.675 ENST00000239165.7
HOXB7
homeobox B7
chr11_+_131240373 2.672 ENST00000374791.3
ENST00000436745.1
NTM

neurotrimin

chr22_-_36236623 2.648 ENST00000405409.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr10_-_92681033 2.617 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr5_-_111092930 2.617 ENST00000257435.7
NREP
neuronal regeneration related protein
chr2_+_54785485 2.613 ENST00000333896.5
SPTBN1
spectrin, beta, non-erythrocytic 1
chr2_-_216257849 2.588 ENST00000456923.1
FN1
fibronectin 1
chr17_-_10421853 2.576 ENST00000226207.5
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chr14_-_92413353 2.569 ENST00000556154.1
FBLN5
fibulin 5
chr7_-_107642348 2.537 ENST00000393561.1
LAMB1
laminin, beta 1
chr3_+_157154578 2.534 ENST00000295927.3
PTX3
pentraxin 3, long
chr2_-_151344172 2.499 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3


Rho family GTPase 3


chr7_+_134576151 2.487 ENST00000393118.2
CALD1
caldesmon 1
chr7_+_134464414 2.478 ENST00000361901.2
CALD1
caldesmon 1
chr6_-_169654139 2.472 ENST00000366787.3
THBS2
thrombospondin 2
chr5_+_174151536 2.391 ENST00000239243.6
ENST00000507785.1
MSX2

msh homeobox 2

chr11_+_101983176 2.326 ENST00000524575.1
YAP1
Yes-associated protein 1
chr22_-_36236265 2.304 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RBFOX2




RNA binding protein, fox-1 homolog (C. elegans) 2




chr11_+_12766583 2.274 ENST00000361985.2
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr3_-_127541194 2.239 ENST00000453507.2
MGLL
monoglyceride lipase
chr19_-_50143452 2.237 ENST00000246792.3
RRAS
related RAS viral (r-ras) oncogene homolog
chr4_-_99578789 2.225 ENST00000511651.1
ENST00000505184.1
TSPAN5

tetraspanin 5

chr12_-_89746173 2.223 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr8_-_18541603 2.219 ENST00000428502.2
PSD3
pleckstrin and Sec7 domain containing 3
chr2_+_66662690 2.180 ENST00000488550.1
MEIS1
Meis homeobox 1
chr12_+_81101277 2.151 ENST00000228641.3
MYF6
myogenic factor 6 (herculin)
chr14_-_92413727 2.119 ENST00000267620.10
FBLN5
fibulin 5
chr13_-_45010939 2.108 ENST00000261489.2
TSC22D1
TSC22 domain family, member 1
chr1_+_84630645 2.106 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr13_+_102142296 2.103 ENST00000376162.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr5_-_111093167 2.096 ENST00000446294.2
ENST00000419114.2
NREP

neuronal regeneration related protein

chr10_+_17270214 2.091 ENST00000544301.1
VIM
vimentin
chr17_-_10325261 2.087 ENST00000403437.2
MYH8
myosin, heavy chain 8, skeletal muscle, perinatal
chr5_-_111093759 2.070 ENST00000509979.1
ENST00000513100.1
ENST00000508161.1
ENST00000455559.2
NREP



neuronal regeneration related protein



chr1_-_95391315 2.021 ENST00000545882.1
ENST00000415017.1
CNN3

calponin 3, acidic

chr2_+_66662510 2.001 ENST00000272369.9
ENST00000407092.2
MEIS1

Meis homeobox 1

chr14_-_53331239 1.995 ENST00000553663.1
FERMT2
fermitin family member 2
chr4_-_143227088 1.994 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr2_+_102508955 1.993 ENST00000414004.2
FLJ20373
FLJ20373
chr4_+_55095264 1.992 ENST00000257290.5
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr4_-_99578776 1.932 ENST00000515287.1
TSPAN5
tetraspanin 5
chr5_+_82767487 1.930 ENST00000343200.5
ENST00000342785.4
VCAN

versican

chr2_-_145277569 1.905 ENST00000303660.4
ZEB2
zinc finger E-box binding homeobox 2
chr18_-_53177984 1.901 ENST00000543082.1
TCF4
transcription factor 4
chr10_+_63661053 1.898 ENST00000279873.7
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr1_-_86043921 1.896 ENST00000535924.2
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr2_+_191792376 1.878 ENST00000409428.1
ENST00000409215.1
GLS

glutaminase

chr12_+_54422142 1.865 ENST00000243108.4
HOXC6
homeobox C6
chr8_+_70404996 1.862 ENST00000402687.4
ENST00000419716.3
SULF1

sulfatase 1

chr1_+_162602244 1.860 ENST00000367922.3
ENST00000367921.3
DDR2

discoidin domain receptor tyrosine kinase 2

chr1_+_78470530 1.815 ENST00000370763.5
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr1_-_203055129 1.813 ENST00000241651.4
MYOG
myogenin (myogenic factor 4)
chr1_-_68698197 1.810 ENST00000370973.2
ENST00000370971.1
WLS

wntless Wnt ligand secretion mediator

chr18_-_53070913 1.809 ENST00000568186.1
ENST00000564228.1
TCF4

transcription factor 4

chr7_+_73442422 1.804 ENST00000358929.4
ENST00000431562.1
ENST00000320492.7
ENST00000438906.1
ELN



elastin



chr8_-_93107443 1.783 ENST00000360348.2
ENST00000520428.1
ENST00000518992.1
ENST00000520556.1
ENST00000518317.1
ENST00000521319.1
ENST00000521375.1
ENST00000518449.1
RUNX1T1







runt-related transcription factor 1; translocated to, 1 (cyclin D-related)







chr1_-_23886285 1.763 ENST00000374561.5
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr9_+_82186872 1.733 ENST00000376544.3
ENST00000376520.4
TLE4

transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)

chr3_-_99569821 1.718 ENST00000487087.1
FILIP1L
filamin A interacting protein 1-like
chr10_-_126716459 1.709 ENST00000309035.6
CTBP2
C-terminal binding protein 2
chr7_+_134576317 1.682 ENST00000424922.1
ENST00000495522.1
CALD1

caldesmon 1

chr3_-_114343039 1.677 ENST00000481632.1
ZBTB20
zinc finger and BTB domain containing 20
chr8_+_9953061 1.662 ENST00000522907.1
ENST00000528246.1
MSRA

methionine sulfoxide reductase A

chr3_-_114790179 1.618 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr7_+_73442487 1.617 ENST00000380575.4
ENST00000380584.4
ENST00000458204.1
ENST00000357036.5
ENST00000417091.1
ENST00000429192.1
ENST00000442310.1
ENST00000380553.4
ENST00000380576.5
ENST00000428787.1
ENST00000320399.6
ELN










elastin










chr7_+_90338712 1.611 ENST00000265741.3
ENST00000406263.1
CDK14

cyclin-dependent kinase 14

chr18_-_53257027 1.604 ENST00000568740.1
ENST00000564403.2
ENST00000537578.1
TCF4


transcription factor 4


chr5_-_88179302 1.603 ENST00000504921.2
MEF2C
myocyte enhancer factor 2C
chr8_+_70378852 1.588 ENST00000525061.1
ENST00000458141.2
ENST00000260128.4
SULF1


sulfatase 1


chr5_+_140810132 1.567 ENST00000252085.3
PCDHGA12
protocadherin gamma subfamily A, 12
chr4_+_169418255 1.562 ENST00000505667.1
ENST00000511948.1
PALLD

palladin, cytoskeletal associated protein

chr12_-_16761007 1.546 ENST00000354662.1
ENST00000441439.2
LMO3

LIM domain only 3 (rhombotin-like 2)

chr4_+_41614909 1.529 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1


LIM and calponin homology domains 1


chr5_+_82767583 1.528 ENST00000512590.2
ENST00000513960.1
ENST00000513984.1
ENST00000502527.2
VCAN



versican



chr2_-_190044480 1.483 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr4_-_186877806 1.481 ENST00000355634.5
SORBS2
sorbin and SH3 domain containing 2
chr8_+_9953214 1.462 ENST00000382490.5
MSRA
methionine sulfoxide reductase A
chr3_+_35721106 1.461 ENST00000474696.1
ENST00000412048.1
ENST00000396482.2
ENST00000432682.1
ARPP21



cAMP-regulated phosphoprotein, 21kDa



chr5_+_102201509 1.444 ENST00000348126.2
ENST00000379787.4
PAM

peptidylglycine alpha-amidating monooxygenase

chr6_+_83072923 1.434 ENST00000535040.1
TPBG
trophoblast glycoprotein
chr1_-_94079648 1.426 ENST00000370247.3
BCAR3
breast cancer anti-estrogen resistance 3
chr3_-_149095652 1.418 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chr3_-_123339343 1.411 ENST00000578202.1
MYLK
myosin light chain kinase
chr12_+_79258444 1.407 ENST00000261205.4
SYT1
synaptotagmin I
chr6_+_83073334 1.403 ENST00000369750.3
TPBG
trophoblast glycoprotein
chr9_-_14180778 1.403 ENST00000380924.1
ENST00000543693.1
NFIB

nuclear factor I/B

chr3_-_114035026 1.400 ENST00000570269.1
RP11-553L6.5
RP11-553L6.5
chr18_-_53069419 1.374 ENST00000570177.2
TCF4
transcription factor 4
chr3_-_79816965 1.374 ENST00000464233.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr8_-_49833978 1.367 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr9_-_14314566 1.366 ENST00000397579.2
NFIB
nuclear factor I/B
chr7_+_73442457 1.364 ENST00000438880.1
ENST00000414324.1
ENST00000380562.4
ELN


elastin


chr12_-_16759711 1.359 ENST00000447609.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr2_-_55237484 1.358 ENST00000394609.2
RTN4
reticulon 4
chr9_-_13175823 1.357 ENST00000545857.1
MPDZ
multiple PDZ domain protein
chr1_+_81771806 1.356 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2





latrophilin 2





chr9_-_14314518 1.333 ENST00000397581.2
NFIB
nuclear factor I/B
chr15_-_56209306 1.315 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
NEDD4


neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase


chr9_-_117880477 1.306 ENST00000534839.1
ENST00000340094.3
ENST00000535648.1
ENST00000346706.3
ENST00000345230.3
ENST00000350763.4
TNC





tenascin C





chr1_-_193155729 1.293 ENST00000367434.4
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr10_+_11206925 1.283 ENST00000354440.2
ENST00000315874.4
ENST00000427450.1
CELF2


CUGBP, Elav-like family member 2


chr9_-_14308004 1.270 ENST00000493697.1
NFIB
nuclear factor I/B
chrX_-_13835147 1.263 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr6_-_46293378 1.253 ENST00000330430.6
RCAN2
regulator of calcineurin 2
chr6_+_114178512 1.253 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr13_-_36429763 1.250 ENST00000379893.1
DCLK1
doublecortin-like kinase 1
chr6_+_12290586 1.247 ENST00000379375.5
EDN1
endothelin 1
chr7_+_90339169 1.240 ENST00000436577.2
CDK14
cyclin-dependent kinase 14
chr5_+_102201722 1.234 ENST00000274392.9
ENST00000455264.2
PAM

peptidylglycine alpha-amidating monooxygenase

chr9_+_82186682 1.217 ENST00000376552.2
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr5_-_111092873 1.213 ENST00000509025.1
ENST00000515855.1
NREP

neuronal regeneration related protein

chr8_-_49834299 1.193 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr3_+_105086056 1.189 ENST00000472644.2
ALCAM
activated leukocyte cell adhesion molecule
chr2_-_208031943 1.187 ENST00000421199.1
ENST00000457962.1
KLF7

Kruppel-like factor 7 (ubiquitous)

chr2_-_145277640 1.171 ENST00000539609.3
ZEB2
zinc finger E-box binding homeobox 2
chr2_-_152589670 1.148 ENST00000604864.1
ENST00000603639.1
NEB

nebulin

chr3_+_105085734 1.142 ENST00000306107.5
ALCAM
activated leukocyte cell adhesion molecule
chr18_-_53253112 1.139 ENST00000568673.1
ENST00000562847.1
ENST00000568147.1
TCF4


transcription factor 4


chr6_-_152639479 1.137 ENST00000356820.4
SYNE1
spectrin repeat containing, nuclear envelope 1
chr3_+_35722487 1.132 ENST00000441454.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr7_-_83824169 1.124 ENST00000265362.4
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr12_+_79258547 1.118 ENST00000457153.2
SYT1
synaptotagmin I
chr12_+_96588143 1.111 ENST00000228741.3
ENST00000547249.1
ELK3

ELK3, ETS-domain protein (SRF accessory protein 2)

chr14_-_92414055 1.107 ENST00000342058.4
FBLN5
fibulin 5
chr11_-_111782696 1.094 ENST00000227251.3
ENST00000526180.1
CRYAB

crystallin, alpha B

chr5_+_119799927 1.090 ENST00000407149.2
ENST00000379551.2
PRR16

proline rich 16

chr4_-_186877502 1.086 ENST00000431902.1
ENST00000284776.7
ENST00000415274.1
SORBS2


sorbin and SH3 domain containing 2


chr2_+_192141611 1.084 ENST00000392316.1
MYO1B
myosin IB
chr12_-_90049878 1.078 ENST00000359142.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr12_-_90049828 1.077 ENST00000261173.2
ENST00000348959.3
ATP2B1

ATPase, Ca++ transporting, plasma membrane 1

chr5_-_111091948 1.075 ENST00000447165.2
NREP
neuronal regeneration related protein
chr2_-_169104651 1.065 ENST00000355999.4
STK39
serine threonine kinase 39
chrX_-_10645773 1.065 ENST00000453318.2
MID1
midline 1 (Opitz/BBB syndrome)
chr2_-_208030647 1.063 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr6_+_21593972 1.052 ENST00000244745.1
ENST00000543472.1
SOX4

SRY (sex determining region Y)-box 4

chr5_-_121413974 1.044 ENST00000231004.4
LOX
lysyl oxidase
chr5_+_155753745 1.044 ENST00000435422.3
ENST00000337851.4
ENST00000447401.1
SGCD


sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)


chr15_+_80351910 1.042 ENST00000261749.6
ENST00000561060.1
ZFAND6

zinc finger, AN1-type domain 6

chr11_-_111794446 1.036 ENST00000527950.1
CRYAB
crystallin, alpha B
chr4_+_72204755 1.034 ENST00000512686.1
ENST00000340595.3
SLC4A4

solute carrier family 4 (sodium bicarbonate cotransporter), member 4

chr10_-_49813090 1.031 ENST00000249601.4
ARHGAP22
Rho GTPase activating protein 22
chr2_+_33359646 1.030 ENST00000390003.4
ENST00000418533.2
LTBP1

latent transforming growth factor beta binding protein 1

chr2_+_201173667 1.026 ENST00000409755.3
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr17_-_26220366 1.024 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
LYRM9


RP1-66C13.4
LYR motif containing 9


Uncharacterized protein
chr2_-_183291741 1.024 ENST00000351439.5
ENST00000409365.1
PDE1A

phosphodiesterase 1A, calmodulin-dependent

chr5_+_102201430 1.009 ENST00000438793.3
ENST00000346918.2
PAM

peptidylglycine alpha-amidating monooxygenase

chr18_-_25616519 1.008 ENST00000399380.3
CDH2
cadherin 2, type 1, N-cadherin (neuronal)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 31.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
1.9 5.8 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
1.4 2.8 GO:0060535 trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536)
1.4 4.1 GO:0007412 axon target recognition(GO:0007412)
1.2 13.3 GO:0060216 definitive hemopoiesis(GO:0060216)
1.1 3.2 GO:0014889 muscle atrophy(GO:0014889) regulation of skeletal muscle tissue growth(GO:0048631)
1.0 3.1 GO:0060340 pericardium morphogenesis(GO:0003344) optic cup formation involved in camera-type eye development(GO:0003408) positive regulation of type I interferon-mediated signaling pathway(GO:0060340) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599)
1.0 8.2 GO:0042693 muscle cell fate commitment(GO:0042693)
0.9 2.8 GO:0090047 obsolete positive regulation of transcription regulator activity(GO:0090047)
0.7 2.2 GO:0035987 endodermal cell fate commitment(GO:0001711) endodermal cell differentiation(GO:0035987)
0.6 1.9 GO:0006543 glutamine catabolic process(GO:0006543)
0.6 1.2 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.6 3.9 GO:0060325 face morphogenesis(GO:0060325)
0.5 1.6 GO:0019731 antibacterial humoral response(GO:0019731)
0.5 2.4 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.5 1.4 GO:0021836 chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.5 1.8 GO:0010716 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.4 2.2 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.4 1.8 GO:0009956 radial pattern formation(GO:0009956)
0.4 3.4 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.4 1.7 GO:0060025 regulation of synaptic activity(GO:0060025)
0.4 5.5 GO:0033687 osteoblast proliferation(GO:0033687)
0.4 2.5 GO:0008228 opsonization(GO:0008228)
0.4 0.8 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.4 2.4 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.4 2.3 GO:0060242 contact inhibition(GO:0060242)
0.4 0.8 GO:0042701 progesterone secretion(GO:0042701)
0.4 2.2 GO:2000124 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.4 2.9 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.3 3.1 GO:0071692 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.3 5.1 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.3 3.0 GO:0008354 germ cell migration(GO:0008354)
0.3 0.7 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.3 6.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.3 0.9 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.3 0.3 GO:0009441 glycolate metabolic process(GO:0009441)
0.2 5.7 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.2 1.5 GO:0032472 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) Golgi calcium ion transport(GO:0032472) manganese ion homeostasis(GO:0055071)
0.2 0.5 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.2 2.9 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.2 0.7 GO:0051451 myoblast migration(GO:0051451)
0.2 1.4 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
0.2 1.8 GO:0030903 notochord development(GO:0030903)
0.2 3.7 GO:0008347 glial cell migration(GO:0008347)
0.2 0.6 GO:0048389 intermediate mesoderm development(GO:0048389) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) trachea formation(GO:0060440) bud elongation involved in lung branching(GO:0060449) bud dilation involved in lung branching(GO:0060503) branch elongation involved in ureteric bud branching(GO:0060681) regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) endothelial tube morphogenesis(GO:0061154) pulmonary artery endothelial tube morphogenesis(GO:0061155) pulmonary artery morphogenesis(GO:0061156) cell proliferation involved in mesonephros development(GO:0061209) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) negative regulation of mesonephros development(GO:0061218) pattern specification involved in mesonephros development(GO:0061227) renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) BMP signaling pathway involved in nephric duct formation(GO:0071893) glomerular visceral epithelial cell development(GO:0072015) comma-shaped body morphogenesis(GO:0072049) regulation of branch elongation involved in ureteric bud branching(GO:0072095) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in kidney development(GO:0072098) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) glomerulus morphogenesis(GO:0072102) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104) mesenchymal cell proliferation involved in ureteric bud development(GO:0072138) nephric duct formation(GO:0072179) ureter urothelium development(GO:0072190) ureter epithelial cell differentiation(GO:0072192) ureter morphogenesis(GO:0072197) metanephric comma-shaped body morphogenesis(GO:0072278) glomerular epithelial cell development(GO:0072310) negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.2 1.1 GO:0002328 pro-B cell differentiation(GO:0002328)
0.2 1.0 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 1.9 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2 0.8 GO:1902116 negative regulation of organelle assembly(GO:1902116)
0.2 0.6 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.2 0.4 GO:0035120 post-embryonic appendage morphogenesis(GO:0035120)
0.2 1.1 GO:0007525 somatic muscle development(GO:0007525)
0.2 0.6 GO:1903115 regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.2 1.3 GO:0032801 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) receptor catabolic process(GO:0032801) regulation of transcription from RNA polymerase II promoter in response to stress(GO:0043618)
0.2 22.8 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.2 1.5 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.2 4.9 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.2 1.1 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.2 6.7 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.2 0.9 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.2 0.6 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.2 3.9 GO:0008038 neuron recognition(GO:0008038)
0.2 3.1 GO:0045446 endothelium development(GO:0003158) endothelial cell differentiation(GO:0045446)
0.2 2.7 GO:0035329 hippo signaling(GO:0035329)
0.1 0.4 GO:0001941 postsynaptic membrane organization(GO:0001941)
0.1 1.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.9 GO:0042730 fibrinolysis(GO:0042730)
0.1 1.9 GO:0050872 white fat cell differentiation(GO:0050872)
0.1 0.6 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.5 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 3.1 GO:0006555 methionine metabolic process(GO:0006555)
0.1 2.6 GO:0034605 cellular response to heat(GO:0034605)
0.1 1.7 GO:0000052 citrulline metabolic process(GO:0000052)
0.1 3.2 GO:0017158 regulation of calcium ion-dependent exocytosis(GO:0017158)
0.1 0.2 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.1 0.9 GO:0003065 regulation of heart rate by chemical signal(GO:0003062) positive regulation of heart rate by epinephrine(GO:0003065)
0.1 0.6 GO:0042474 middle ear morphogenesis(GO:0042474)
0.1 1.1 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.1 0.3 GO:0030035 microspike assembly(GO:0030035)
0.1 7.2 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 0.3 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 0.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 4.2 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.1 1.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 1.3 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 0.1 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.1 1.0 GO:0031641 regulation of myelination(GO:0031641)
0.1 4.2 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.1 1.7 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.5 GO:0055062 phosphate ion homeostasis(GO:0055062) divalent inorganic anion homeostasis(GO:0072505) trivalent inorganic anion homeostasis(GO:0072506)
0.1 18.7 GO:0007517 muscle organ development(GO:0007517)
0.1 2.2 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 0.6 GO:0071320 cellular response to cAMP(GO:0071320)
0.1 3.0 GO:0051101 regulation of DNA binding(GO:0051101)
0.1 1.0 GO:1901797 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.1 0.2 GO:0045760 positive regulation of action potential(GO:0045760)
0.1 0.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.1 GO:0010658 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1 0.7 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 6.0 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.1 0.5 GO:0032528 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.1 0.8 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.1 2.8 GO:0060271 cilium morphogenesis(GO:0060271)
0.1 3.9 GO:0009408 response to heat(GO:0009408)
0.1 2.5 GO:0008016 regulation of heart contraction(GO:0008016)
0.1 0.7 GO:0031529 ruffle organization(GO:0031529)
0.1 2.6 GO:0060828 regulation of canonical Wnt signaling pathway(GO:0060828)
0.1 0.2 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.6 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 0.3 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.1 0.4 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 0.3 GO:0097531 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1 3.1 GO:0031032 actomyosin structure organization(GO:0031032)
0.1 0.6 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.1 0.3 GO:0051963 regulation of synapse assembly(GO:0051963)
0.0 0.2 GO:0006848 pyruvate transport(GO:0006848)
0.0 0.9 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.4 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 1.1 GO:0050850 positive regulation of calcium-mediated signaling(GO:0050850)
0.0 0.2 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.5 GO:0006907 pinocytosis(GO:0006907)
0.0 0.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0009299 mRNA transcription(GO:0009299)
0.0 0.5 GO:0051654 establishment of mitochondrion localization(GO:0051654)
0.0 8.4 GO:0006936 muscle contraction(GO:0006936)
0.0 2.3 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 1.0 GO:0051180 vitamin transport(GO:0051180)
0.0 1.5 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.7 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.3 GO:0006184 obsolete GTP catabolic process(GO:0006184)
0.0 0.3 GO:0035315 hair cell differentiation(GO:0035315) auditory receptor cell differentiation(GO:0042491)
0.0 0.5 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.8 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.0 0.1 GO:0001569 patterning of blood vessels(GO:0001569)
0.0 2.2 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.0 0.2 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.3 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.7 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.3 GO:0008272 sulfate transport(GO:0008272)
0.0 0.5 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 1.4 GO:0006754 ATP biosynthetic process(GO:0006754)
0.0 2.7 GO:0043087 regulation of GTPase activity(GO:0043087)
0.0 0.1 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 1.6 GO:0007265 Ras protein signal transduction(GO:0007265)
0.0 1.4 GO:0070304 positive regulation of stress-activated MAPK cascade(GO:0032874) positive regulation of stress-activated protein kinase signaling cascade(GO:0070304)
0.0 0.1 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.0 3.0 GO:0030036 actin cytoskeleton organization(GO:0030036)
0.0 2.8 GO:0050658 nucleic acid transport(GO:0050657) RNA transport(GO:0050658) establishment of RNA localization(GO:0051236)
0.0 0.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.4 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 1.8 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 0.1 GO:0044253 positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.0 0.2 GO:1901224 activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0 0.2 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 3.7 GO:0006260 DNA replication(GO:0006260)
0.0 1.0 GO:0006986 response to unfolded protein(GO:0006986)
0.0 0.2 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0046174 polyol catabolic process(GO:0046174)
0.0 0.3 GO:0043631 RNA polyadenylation(GO:0043631)
0.0 0.1 GO:0032230 positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.0 0.1 GO:0000042 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0 0.4 GO:0030866 cortical cytoskeleton organization(GO:0030865) cortical actin cytoskeleton organization(GO:0030866)
0.0 5.1 GO:0016567 protein ubiquitination(GO:0016567)
0.0 0.4 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.1 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.0 0.1 GO:0051319 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 2.8 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 31.1 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.9 5.8 GO:0071953 elastic fiber(GO:0071953)
1.0 2.9 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.8 2.5 GO:0005607 laminin-2 complex(GO:0005607)
0.6 3.2 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.5 1.5 GO:0005588 collagen type V trimer(GO:0005588)
0.4 1.8 GO:0071438 invadopodium membrane(GO:0071438)
0.3 6.3 GO:0032982 myosin filament(GO:0032982)
0.3 0.8 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2 2.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.2 1.7 GO:0005581 collagen trimer(GO:0005581)
0.2 4.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 2.5 GO:0008091 spectrin(GO:0008091)
0.1 1.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.0 GO:0016342 catenin complex(GO:0016342)
0.1 0.9 GO:0070852 cell body fiber(GO:0070852)
0.1 6.5 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.1 0.9 GO:1990752 microtubule plus-end(GO:0035371) microtubule end(GO:1990752)
0.1 1.0 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 23.9 GO:0030016 myofibril(GO:0030016)
0.1 2.7 GO:0032589 neuron projection membrane(GO:0032589)
0.1 1.0 GO:0043202 lysosomal lumen(GO:0043202)
0.1 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 24.5 GO:0005667 transcription factor complex(GO:0005667)
0.1 1.3 GO:0043073 germ cell nucleus(GO:0043073)
0.1 0.7 GO:0005884 actin filament(GO:0005884)
0.1 2.7 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 18.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 2.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.2 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 2.8 GO:0016459 myosin complex(GO:0016459)
0.0 0.0 GO:0045177 apical plasma membrane(GO:0016324) apical part of cell(GO:0045177)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 4.6 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 3.5 GO:0005802 trans-Golgi network(GO:0005802)
0.0 7.8 GO:0030424 axon(GO:0030424)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 0.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 2.8 GO:0030027 lamellipodium(GO:0030027)
0.0 3.4 GO:0005795 Golgi stack(GO:0005795)
0.0 0.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 3.3 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.7 GO:0031252 cell leading edge(GO:0031252)
0.0 1.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.5 GO:0031526 brush border membrane(GO:0031526)
0.0 0.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.2 GO:0016605 PML body(GO:0016605)
0.0 0.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.6 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 1.0 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 15.5 GO:0005730 nucleolus(GO:0005730)
0.0 0.2 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.3 GO:0005902 microvillus(GO:0005902)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 23.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093)
1.1 5.6 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
1.1 4.4 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.9 5.5 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.9 5.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.8 4.0 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.7 29.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.7 2.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.5 1.5 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.5 3.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.5 1.9 GO:0004359 glutaminase activity(GO:0004359)
0.5 1.4 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.4 1.3 GO:0050816 beta-2 adrenergic receptor binding(GO:0031698) phosphothreonine binding(GO:0050816)
0.4 1.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.4 3.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.4 1.9 GO:0016403 dimethylargininase activity(GO:0016403)
0.4 11.5 GO:0005523 tropomyosin binding(GO:0005523)
0.4 5.7 GO:0070888 E-box binding(GO:0070888)
0.3 3.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.3 4.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.3 6.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.3 1.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.3 0.8 GO:0048184 obsolete follistatin binding(GO:0048184)
0.2 1.2 GO:0031708 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.2 3.2 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.2 1.5 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.2 3.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.2 1.6 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.2 1.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 1.3 GO:0045545 syndecan binding(GO:0045545)
0.2 1.0 GO:0045499 chemorepellent activity(GO:0045499)
0.2 1.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510) bicarbonate transmembrane transporter activity(GO:0015106)
0.2 1.6 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2 4.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 2.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 0.7 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.2 0.8 GO:0005534 galactose binding(GO:0005534)
0.2 2.8 GO:0030332 cyclin binding(GO:0030332)
0.1 2.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 2.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.6 GO:0051637 obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.1 0.4 GO:0000150 recombinase activity(GO:0000150)
0.1 1.3 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 1.2 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.1 1.8 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1 0.4 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.1 0.6 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.1 2.3 GO:0070064 proline-rich region binding(GO:0070064)
0.1 3.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 2.5 GO:0000146 microfilament motor activity(GO:0000146)
0.1 5.7 GO:0046332 SMAD binding(GO:0046332)
0.1 1.9 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.4 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 3.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 3.7 GO:0005518 collagen binding(GO:0005518)
0.1 1.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 1.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 3.0 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.1 0.7 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 1.3 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 0.1 GO:0004221 obsolete ubiquitin thiolesterase activity(GO:0004221)
0.1 0.6 GO:0042731 PH domain binding(GO:0042731)
0.1 1.0 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 1.7 GO:0042056 chemoattractant activity(GO:0042056)
0.1 2.2 GO:0019003 GDP binding(GO:0019003)
0.1 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 1.1 GO:0005521 lamin binding(GO:0005521)
0.1 0.6 GO:0031014 troponin T binding(GO:0031014)
0.1 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.9 GO:0070628 proteasome binding(GO:0070628)
0.1 2.7 GO:0005080 protein kinase C binding(GO:0005080)
0.1 0.3 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1 5.4 GO:0005178 integrin binding(GO:0005178)
0.1 1.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 3.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0050833 pyruvate secondary active transmembrane transporter activity(GO:0005477) pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.8 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.4 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.2 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.7 GO:0005522 profilin binding(GO:0005522)
0.0 3.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 4.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 4.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.3 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.8 GO:0004697 protein kinase C activity(GO:0004697)
0.0 3.5 GO:0008201 heparin binding(GO:0008201)
0.0 1.1 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.4 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.4 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.2 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.4 GO:0016944 obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.8 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.3 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.4 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.6 GO:1990782 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0 0.2 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.7 GO:0051287 NAD binding(GO:0051287)
0.0 3.3 GO:0003774 motor activity(GO:0003774)
0.0 5.5 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.5 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.2 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.2 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 3.3 GO:0008083 growth factor activity(GO:0008083)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.2 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.2 GO:0005123 death receptor binding(GO:0005123)
0.0 0.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 1.8 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.1 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0008907 integrase activity(GO:0008907)
0.0 0.1 GO:0043621 protein self-association(GO:0043621)
0.0 1.4 GO:0008194 UDP-glycosyltransferase activity(GO:0008194)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.1 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 4.4 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.0 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.5 SIG_CD40PATHWAYMAP Genes related to CD40 signaling