Motif ID: HOXC11
Z-value: 0.831
Transcription factors associated with HOXC11:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| HOXC11 | ENSG00000123388.4 | HOXC11 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 3.9 | GO:0051918 | negative regulation of fibrinolysis(GO:0051918) |
| 0.4 | 1.4 | GO:0048619 | embryonic hindgut morphogenesis(GO:0048619) |
| 0.3 | 0.8 | GO:0060024 | rhythmic synaptic transmission(GO:0060024) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585) |
| 0.3 | 0.8 | GO:0021836 | chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923) |
| 0.2 | 1.5 | GO:0034695 | response to prostaglandin E(GO:0034695) |
| 0.1 | 0.4 | GO:0071400 | cellular response to oleic acid(GO:0071400) |
| 0.1 | 0.8 | GO:0014049 | positive regulation of glutamate secretion(GO:0014049) |
| 0.1 | 0.6 | GO:0071699 | olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699) |
| 0.1 | 0.3 | GO:0007181 | transforming growth factor beta receptor complex assembly(GO:0007181) |
| 0.1 | 0.6 | GO:0023041 | neuronal signal transduction(GO:0023041) |
| 0.1 | 1.1 | GO:0034372 | triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372) |
| 0.1 | 0.3 | GO:0060164 | regulation of timing of neuron differentiation(GO:0060164) |
| 0.1 | 0.7 | GO:0042572 | retinol metabolic process(GO:0042572) |
| 0.1 | 0.2 | GO:0034720 | histone H3-K4 demethylation(GO:0034720) |
| 0.0 | 0.6 | GO:0060706 | cell differentiation involved in embryonic placenta development(GO:0060706) |
| 0.0 | 0.1 | GO:0002384 | hepatic immune response(GO:0002384) positive regulation of immunoglobulin secretion(GO:0051024) positive regulation of transmission of nerve impulse(GO:0051971) |
| 0.0 | 0.3 | GO:0021830 | cerebral cortex tangential migration(GO:0021800) interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936) |
| 0.0 | 0.1 | GO:0006542 | glutamine biosynthetic process(GO:0006542) |
| 0.0 | 0.1 | GO:0006540 | glutamate decarboxylation to succinate(GO:0006540) |
| 0.0 | 0.1 | GO:0060743 | epithelial cell maturation involved in prostate gland development(GO:0060743) |
| 0.0 | 0.2 | GO:0051570 | regulation of histone H3-K9 methylation(GO:0051570) |
| 0.0 | 0.2 | GO:0060216 | definitive hemopoiesis(GO:0060216) |
| 0.0 | 0.1 | GO:0070309 | lens fiber cell morphogenesis(GO:0070309) |
| 0.0 | 0.1 | GO:0015824 | proline transport(GO:0015824) |
| 0.0 | 0.4 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.0 | 0.1 | GO:0021615 | glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615) |
| 0.0 | 1.8 | GO:0042742 | defense response to bacterium(GO:0042742) |
| 0.0 | 0.1 | GO:0048296 | isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296) positive regulation of isotype switching to IgA isotypes(GO:0048298) |
| 0.0 | 0.6 | GO:0048286 | lung alveolus development(GO:0048286) |
| 0.0 | 0.1 | GO:0031018 | endocrine pancreas development(GO:0031018) |
| 0.0 | 0.2 | GO:0060736 | prostate gland growth(GO:0060736) |
| 0.0 | 0.0 | GO:0071436 | sodium ion export(GO:0071436) |
| 0.0 | 0.3 | GO:0051881 | regulation of mitochondrial membrane potential(GO:0051881) |
| 0.0 | 0.1 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672) |
| 0.0 | 0.2 | GO:0006704 | glucocorticoid biosynthetic process(GO:0006704) |
| 0.0 | 0.2 | GO:0001660 | fever generation(GO:0001660) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.4 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) beta-catenin-TCF complex(GO:1990907) |
| 0.2 | 1.6 | GO:0005587 | collagen type IV trimer(GO:0005587) |
| 0.1 | 0.5 | GO:0070288 | intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288) |
| 0.1 | 0.7 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.0 | 0.8 | GO:0043034 | costamere(GO:0043034) |
| 0.0 | 0.2 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 0.1 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 0.0 | 1.1 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.0 | 0.7 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.0 | 0.1 | GO:0061200 | clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202) |
| 0.0 | 0.1 | GO:0070081 | clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083) |
| 0.0 | 2.7 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.0 | 0.0 | GO:0033011 | perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150) |
| 0.0 | 0.2 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.1 | GO:0004607 | phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607) |
| 0.2 | 0.7 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.2 | 3.8 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.2 | 0.8 | GO:0031708 | bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708) |
| 0.1 | 0.8 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.1 | 1.4 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.1 | 0.8 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
| 0.1 | 0.2 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
| 0.1 | 0.4 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
| 0.1 | 0.3 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.1 | 0.2 | GO:0043426 | histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648) MRF binding(GO:0043426) |
| 0.0 | 1.5 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.0 | 0.4 | GO:0016595 | glutamate binding(GO:0016595) |
| 0.0 | 0.7 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.0 | 0.5 | GO:0008199 | ferric iron binding(GO:0008199) |
| 0.0 | 0.1 | GO:0016211 | glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880) |
| 0.0 | 1.8 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.0 | 0.1 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
| 0.0 | 1.5 | GO:0042562 | hormone binding(GO:0042562) |
| 0.0 | 0.3 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.0 | 0.4 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.0 | 0.1 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.0 | 0.1 | GO:0008504 | monoamine transmembrane transporter activity(GO:0008504) |
| 0.0 | 0.1 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.0 | 0.3 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.0 | 0.0 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
| 0.0 | 0.2 | GO:0005003 | ephrin receptor activity(GO:0005003) |
| 0.0 | 0.2 | GO:0032452 | histone demethylase activity(GO:0032452) |
