Motif ID: HOXC6_HOXA7

Z-value: 0.935

Transcription factors associated with HOXC6_HOXA7:

Gene SymbolEntrez IDGene Name
HOXA7 ENSG00000122592.6 HOXA7
HOXC6 ENSG00000197757.7 HOXC6






Network of associatons between targets according to the STRING database.



First level regulatory network of HOXC6_HOXA7

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_91573132 1.704 ENST00000550563.1
ENST00000546370.1
DCN

decorin

chr12_-_91573316 1.687 ENST00000393155.1
DCN
decorin
chr12_-_91573249 1.528 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
DCN


decorin


chr9_+_125132803 1.339 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr15_+_67418047 1.137 ENST00000540846.2
SMAD3
SMAD family member 3
chr17_+_1674982 1.120 ENST00000572048.1
ENST00000573763.1
SERPINF1

serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1

chr3_+_157154578 1.009 ENST00000295927.3
PTX3
pentraxin 3, long
chr9_+_125133315 1.007 ENST00000223423.4
ENST00000362012.2
PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

chr5_+_95066823 0.922 ENST00000506817.1
ENST00000379982.3
RHOBTB3

Rho-related BTB domain containing 3

chr2_+_152214098 0.598 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr19_+_50016610 0.597 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr8_-_41166953 0.466 ENST00000220772.3
SFRP1
secreted frizzled-related protein 1
chr7_+_93551011 0.461 ENST00000248564.5
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr6_+_26365443 0.442 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
BTN3A2





butyrophilin, subfamily 3, member A2





chr20_-_50384864 0.430 ENST00000311637.5
ENST00000402822.1
ATP9A

ATPase, class II, type 9A

chr3_+_132316081 0.404 ENST00000249887.2
ACKR4
atypical chemokine receptor 4
chr8_-_93115445 0.376 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr12_+_60083118 0.345 ENST00000261187.4
ENST00000543448.1
SLC16A7

solute carrier family 16 (monocarboxylate transporter), member 7

chr13_-_36050819 0.342 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr14_-_90085458 0.331 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
FOXN3


forkhead box N3


chr12_+_26348246 0.310 ENST00000422622.2
SSPN
sarcospan
chr11_-_63376013 0.292 ENST00000540943.1
PLA2G16
phospholipase A2, group XVI
chr17_-_46688334 0.272 ENST00000239165.7
HOXB7
homeobox B7
chr6_+_114178512 0.272 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr6_+_26440700 0.235 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
BTN3A3









butyrophilin, subfamily 3, member A3









chr12_+_26348429 0.226 ENST00000242729.2
SSPN
sarcospan
chr18_+_32558208 0.219 ENST00000436190.2
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr19_+_50016411 0.208 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
FCGRT


Fc fragment of IgG, receptor, transporter, alpha


chr12_+_64798095 0.199 ENST00000332707.5
XPOT
exportin, tRNA
chr7_+_134528635 0.199 ENST00000445569.2
CALD1
caldesmon 1
chrX_+_9431324 0.191 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X





transducin (beta)-like 1X-linked





chr4_-_100009856 0.187 ENST00000296412.8
ADH5
alcohol dehydrogenase 5 (class III), chi polypeptide
chr14_+_50234309 0.177 ENST00000298307.5
KLHDC2
kelch domain containing 2
chr11_-_124670550 0.174 ENST00000239614.4
MSANTD2
Myb/SANT-like DNA-binding domain containing 2
chr6_+_96969672 0.172 ENST00000369278.4
UFL1
UFM1-specific ligase 1
chr11_+_66276550 0.170 ENST00000419755.3
CTD-3074O7.11
Bardet-Biedl syndrome 1 protein
chr9_-_95166841 0.159 ENST00000262551.4
OGN
osteoglycin
chr4_-_185275104 0.154 ENST00000317596.3
RP11-290F5.2
RP11-290F5.2
chr2_+_90248739 0.149 ENST00000468879.1
IGKV1D-43
immunoglobulin kappa variable 1D-43
chr11_-_104827425 0.146 ENST00000393150.3
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr13_+_53602894 0.145 ENST00000219022.2
OLFM4
olfactomedin 4
chr15_-_55657428 0.143 ENST00000568543.1
CCPG1
cell cycle progression 1
chr12_-_10022735 0.124 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr14_-_94789663 0.123 ENST00000557225.1
ENST00000341584.3
SERPINA6

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6

chr19_+_49404041 0.123 ENST00000263273.5
ENST00000424608.1
NUCB1

nucleobindin 1

chr16_-_29934558 0.121 ENST00000568995.1
ENST00000566413.1
KCTD13

potassium channel tetramerization domain containing 13

chr8_-_57123815 0.118 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1


pleiomorphic adenoma gene 1


chr2_+_90211643 0.114 ENST00000390277.2
IGKV3D-11
immunoglobulin kappa variable 3D-11
chr6_+_26402465 0.113 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
BTN3A1





butyrophilin, subfamily 3, member A1





chr3_-_194188956 0.113 ENST00000256031.4
ENST00000446356.1
ATP13A3

ATPase type 13A3

chr1_+_221051699 0.107 ENST00000366903.6
HLX
H2.0-like homeobox
chr17_-_64225508 0.107 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr2_+_90273679 0.106 ENST00000423080.2
IGKV3D-7
immunoglobulin kappa variable 3D-7
chr4_+_71108300 0.105 ENST00000304954.3
CSN3
casein kappa
chr6_-_109702885 0.101 ENST00000504373.1
CD164
CD164 molecule, sialomucin
chr2_-_89327228 0.100 ENST00000483158.1
IGKV3-11
immunoglobulin kappa variable 3-11
chr14_-_23058063 0.093 ENST00000538631.1
ENST00000543337.1
ENST00000250498.4
DAD1


defender against cell death 1


chr1_+_202317815 0.091 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
PPP1R12B


protein phosphatase 1, regulatory subunit 12B


chr7_+_130794846 0.088 ENST00000421797.2
MKLN1
muskelin 1, intracellular mediator containing kelch motifs
chr18_-_7117813 0.086 ENST00000389658.3
LAMA1
laminin, alpha 1
chr19_-_14945933 0.078 ENST00000322301.3
OR7A5
olfactory receptor, family 7, subfamily A, member 5
chr11_+_86748863 0.077 ENST00000340353.7
TMEM135
transmembrane protein 135
chrX_-_18690210 0.075 ENST00000379984.3
RS1
retinoschisin 1
chr17_-_39623681 0.074 ENST00000225899.3
KRT32
keratin 32
chr2_-_89340242 0.071 ENST00000480492.1
IGKV1-12
immunoglobulin kappa variable 1-12
chrX_-_130423200 0.070 ENST00000361420.3
IGSF1
immunoglobulin superfamily, member 1
chr1_+_117544366 0.070 ENST00000256652.4
ENST00000369470.1
CD101

CD101 molecule

chr15_+_64680003 0.069 ENST00000261884.3
TRIP4
thyroid hormone receptor interactor 4
chr5_+_40909354 0.069 ENST00000313164.9
C7
complement component 7
chr11_+_33061543 0.067 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
TCP11L1


t-complex 11, testis-specific-like 1


chr8_-_62602327 0.066 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
ASPH









aspartate beta-hydroxylase









chr2_-_74618964 0.065 ENST00000417090.1
ENST00000409868.1
DCTN1

dynactin 1

chr14_-_106552755 0.063 ENST00000390600.2
IGHV3-9
immunoglobulin heavy variable 3-9
chr19_-_54618650 0.062 ENST00000391757.1
TFPT
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr10_-_112678692 0.060 ENST00000605742.1
BBIP1
BBSome interacting protein 1
chr7_-_22862406 0.058 ENST00000372879.4
TOMM7
translocase of outer mitochondrial membrane 7 homolog (yeast)
chr5_+_162930114 0.056 ENST00000280969.5
MAT2B
methionine adenosyltransferase II, beta
chr3_-_167191814 0.053 ENST00000466903.1
ENST00000264677.4
SERPINI2

serpin peptidase inhibitor, clade I (pancpin), member 2

chr4_-_170533723 0.051 ENST00000510533.1
ENST00000439128.2
ENST00000511633.1
ENST00000512193.1
ENST00000507142.1
NEK1




NIMA-related kinase 1




chr10_+_18549645 0.051 ENST00000396576.2
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr5_-_16916624 0.050 ENST00000513882.1
MYO10
myosin X
chr10_-_112678976 0.050 ENST00000448814.1
BBIP1
BBSome interacting protein 1
chr19_-_54619006 0.050 ENST00000391759.1
TFPT
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr7_-_122635754 0.047 ENST00000249284.2
TAS2R16
taste receptor, type 2, member 16
chr7_-_44122063 0.046 ENST00000335195.6
ENST00000395831.3
ENST00000414235.1
ENST00000452049.1
ENST00000242248.5
POLM




polymerase (DNA directed), mu




chr17_+_35851570 0.042 ENST00000394386.1
DUSP14
dual specificity phosphatase 14
chr2_+_90198535 0.041 ENST00000390276.2
IGKV1D-12
immunoglobulin kappa variable 1D-12
chr19_-_51920952 0.040 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
SIGLEC10





sialic acid binding Ig-like lectin 10





chr2_-_74619152 0.039 ENST00000440727.1
ENST00000409240.1
DCTN1

dynactin 1

chr4_+_155484155 0.039 ENST00000509493.1
FGB
fibrinogen beta chain
chr11_-_77791156 0.039 ENST00000281031.4
NDUFC2
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
chr10_-_112678904 0.039 ENST00000423273.1
ENST00000436562.1
ENST00000447005.1
ENST00000454061.1
BBIP1



BBSome interacting protein 1



chr15_+_25068773 0.037 ENST00000400100.1
ENST00000400098.1
SNRPN

small nuclear ribonucleoprotein polypeptide N

chr4_-_80329356 0.037 ENST00000358842.3
GK2
glycerol kinase 2
chr14_-_106926724 0.036 ENST00000434710.1
IGHV3-43
immunoglobulin heavy variable 3-43
chr11_-_77790865 0.035 ENST00000534029.1
ENST00000525085.1
ENST00000527806.1
ENST00000528164.1
ENST00000528251.1
ENST00000530054.1
NDUFC2



NDUFC2-KCTD14

NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa



NDUFC2-KCTD14 readthrough

chr2_+_202098166 0.033 ENST00000392263.2
ENST00000264274.9
ENST00000392259.2
ENST00000392266.3
ENST00000432109.2
ENST00000264275.5
CASP8





caspase 8, apoptosis-related cysteine peptidase





chr11_-_13517565 0.032 ENST00000282091.1
ENST00000529816.1
PTH

parathyroid hormone

chr10_+_112679301 0.032 ENST00000265277.5
ENST00000369452.4
SHOC2

soc-2 suppressor of clear homolog (C. elegans)

chr17_-_4938712 0.030 ENST00000254853.5
ENST00000424747.1
SLC52A1

solute carrier family 52 (riboflavin transporter), member 1

chr16_+_12059050 0.029 ENST00000396495.3
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr2_+_202047843 0.028 ENST00000272879.5
ENST00000374650.3
ENST00000346817.5
ENST00000313728.7
ENST00000448480.1
CASP10




caspase 10, apoptosis-related cysteine peptidase




chr10_+_90424196 0.028 ENST00000394375.3
ENST00000608620.1
ENST00000238983.4
ENST00000355843.2
LIPF



lipase, gastric



chr16_-_28634874 0.027 ENST00000395609.1
ENST00000350842.4
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr5_-_20575959 0.027 ENST00000507958.1
CDH18
cadherin 18, type 2
chr21_-_31538971 0.027 ENST00000286808.3
CLDN17
claudin 17
chr19_+_49199209 0.026 ENST00000522966.1
ENST00000425340.2
ENST00000391876.4
FUT2


fucosyltransferase 2 (secretor status included)


chr19_-_5903714 0.025 ENST00000252675.5
ENST00000308961.4
ENST00000592634.1
ENST00000418389.2
ENST00000586349.1
ENST00000585661.1
FUT5
NDUFA11


AC024592.12

fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa


Uncharacterized protein

chr3_-_39321512 0.025 ENST00000399220.2
CX3CR1
chemokine (C-X3-C motif) receptor 1
chr14_-_23426270 0.024 ENST00000557591.1
ENST00000397409.4
ENST00000490506.1
ENST00000554406.1
HAUS4



HAUS augmin-like complex, subunit 4



chr6_+_28092338 0.023 ENST00000340487.4
ZSCAN16
zinc finger and SCAN domain containing 16
chr11_+_2405833 0.022 ENST00000527343.1
ENST00000464784.2
CD81

CD81 molecule

chr2_-_25391425 0.022 ENST00000264708.3
ENST00000449220.1
POMC

proopiomelanocortin

chr7_+_150020329 0.022 ENST00000323078.7
LRRC61
leucine rich repeat containing 61
chr6_+_46761118 0.022 ENST00000230588.4
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr2_-_25391507 0.020 ENST00000380794.1
POMC
proopiomelanocortin
chr5_-_86534822 0.020 ENST00000445770.2
AC008394.1
Uncharacterized protein
chr13_+_31309645 0.019 ENST00000380490.3
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr4_+_169418255 0.019 ENST00000505667.1
ENST00000511948.1
PALLD

palladin, cytoskeletal associated protein

chr14_-_23426337 0.018 ENST00000342454.8
ENST00000555986.1
ENST00000541587.1
ENST00000554516.1
ENST00000347758.2
ENST00000206474.7
ENST00000555040.1
HAUS4






HAUS augmin-like complex, subunit 4






chr2_-_25391468 0.018 ENST00000395826.2
POMC
proopiomelanocortin
chr14_-_23426322 0.016 ENST00000555367.1
HAUS4
HAUS augmin-like complex, subunit 4
chr4_+_169418195 0.016 ENST00000261509.6
ENST00000335742.7
PALLD

palladin, cytoskeletal associated protein

chr14_-_106668095 0.015 ENST00000390606.2
IGHV3-20
immunoglobulin heavy variable 3-20
chr10_-_101989315 0.015 ENST00000370397.7
CHUK
conserved helix-loop-helix ubiquitous kinase
chr16_-_28937027 0.015 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr2_-_25391772 0.015 ENST00000405623.1
POMC
proopiomelanocortin
chr3_+_138340067 0.013 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr7_-_22862448 0.011 ENST00000358435.4
TOMM7
translocase of outer mitochondrial membrane 7 homolog (yeast)
chr5_+_140625147 0.010 ENST00000231173.3
PCDHB15
protocadherin beta 15
chr7_+_141811539 0.009 ENST00000550469.2
ENST00000477922.3
RP11-1220K2.2

Putative inactive maltase-glucoamylase-like protein LOC93432

chr7_+_150020363 0.008 ENST00000359623.4
ENST00000493307.1
LRRC61

leucine rich repeat containing 61

chr2_+_202047596 0.007 ENST00000286186.6
ENST00000360132.3
CASP10

caspase 10, apoptosis-related cysteine peptidase

chr1_+_8021954 0.007 ENST00000377491.1
ENST00000377488.1
PARK7

parkinson protein 7

chrX_-_16887963 0.004 ENST00000380084.4
RBBP7
retinoblastoma binding protein 7
chr5_-_22853429 0.004 ENST00000504376.2
CDH12
cadherin 12, type 2 (N-cadherin 2)
chr1_-_92952433 0.002 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chr6_-_36515177 0.001 ENST00000229812.7
STK38
serine/threonine kinase 38
chr9_-_27005686 0.001 ENST00000380055.5
LRRC19
leucine rich repeat containing 19
chr17_-_10372875 0.000 ENST00000255381.2
MYH4
myosin, heavy chain 4, skeletal muscle

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.4 4.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 1.1 GO:0007614 short-term memory(GO:0007614)
0.2 1.0 GO:0008228 opsonization(GO:0008228)
0.2 1.1 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.2 0.5 GO:0014029 neural crest formation(GO:0014029) neural crest cell fate commitment(GO:0014034) convergent extension involved in axis elongation(GO:0060028) cellular response to prostaglandin E stimulus(GO:0071380) response to heparin(GO:0071503) cellular response to heparin(GO:0071504) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.3 GO:0006848 pyruvate transport(GO:0006848)
0.1 0.2 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.0 0.9 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.3 GO:0051319 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.1 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.9 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.8 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:0005608 laminin-3 complex(GO:0005608)
0.0 1.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0034464 BBSome(GO:0034464)
0.0 0.3 GO:0043073 germ cell nucleus(GO:0043073)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.2 0.8 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.2 1.1 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 4.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.3 GO:0050833 pyruvate secondary active transmembrane transporter activity(GO:0005477) pyruvate transmembrane transporter activity(GO:0050833)
0.1 1.0 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.9 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.1 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0004623 phospholipase A2 activity(GO:0004623)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.5 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway