Motif ID: HOXC8
Z-value: 0.972
Transcription factors associated with HOXC8:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
HOXC8 | ENSG00000037965.4 | HOXC8 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.9 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) |
0.3 | 1.6 | GO:0006789 | bilirubin conjugation(GO:0006789) biphenyl metabolic process(GO:0018879) biphenyl catabolic process(GO:0070980) |
0.3 | 1.6 | GO:0043312 | neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312) |
0.3 | 0.8 | GO:0010902 | positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902) positive regulation of phospholipid catabolic process(GO:0060697) |
0.3 | 1.0 | GO:0006542 | glutamine biosynthetic process(GO:0006542) |
0.2 | 0.7 | GO:0033278 | cell proliferation in midbrain(GO:0033278) |
0.2 | 0.6 | GO:0003308 | negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) |
0.2 | 0.6 | GO:0046010 | positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010) |
0.2 | 0.7 | GO:0060649 | nipple development(GO:0060618) mammary gland bud elongation(GO:0060649) nipple morphogenesis(GO:0060658) nipple sheath formation(GO:0060659) |
0.2 | 0.6 | GO:0051552 | flavone metabolic process(GO:0051552) |
0.1 | 0.4 | GO:0060689 | cell differentiation involved in salivary gland development(GO:0060689) |
0.1 | 0.5 | GO:0051503 | purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) |
0.1 | 0.5 | GO:0071400 | cellular response to oleic acid(GO:0071400) |
0.1 | 0.4 | GO:0002514 | B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663) |
0.1 | 0.5 | GO:0001575 | globoside metabolic process(GO:0001575) |
0.1 | 0.5 | GO:0050653 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653) |
0.1 | 1.1 | GO:0051918 | negative regulation of fibrinolysis(GO:0051918) |
0.1 | 0.6 | GO:0060242 | contact inhibition(GO:0060242) |
0.1 | 3.1 | GO:0031424 | keratinization(GO:0031424) |
0.1 | 0.5 | GO:0006927 | obsolete transformed cell apoptotic process(GO:0006927) |
0.1 | 0.4 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
0.1 | 0.4 | GO:0008065 | establishment of blood-nerve barrier(GO:0008065) |
0.1 | 2.5 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
0.1 | 0.3 | GO:0006530 | asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345) |
0.1 | 1.2 | GO:0060391 | positive regulation of SMAD protein import into nucleus(GO:0060391) |
0.1 | 1.1 | GO:0030299 | intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856) |
0.1 | 0.3 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
0.1 | 0.4 | GO:0006883 | cellular sodium ion homeostasis(GO:0006883) |
0.1 | 0.2 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
0.1 | 0.2 | GO:0003350 | pulmonary myocardium development(GO:0003350) |
0.1 | 0.3 | GO:0045338 | farnesyl diphosphate metabolic process(GO:0045338) |
0.1 | 0.2 | GO:2000105 | positive regulation of DNA-dependent DNA replication initiation(GO:0032298) positive regulation of DNA-dependent DNA replication(GO:2000105) |
0.1 | 0.3 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
0.1 | 0.1 | GO:0002675 | positive regulation of acute inflammatory response(GO:0002675) |
0.1 | 0.3 | GO:0042271 | susceptibility to natural killer cell mediated cytotoxicity(GO:0042271) |
0.1 | 0.2 | GO:0032071 | obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922) regulation of endodeoxyribonuclease activity(GO:0032071) negative regulation of nuclease activity(GO:0032074) |
0.1 | 1.7 | GO:0006693 | prostaglandin metabolic process(GO:0006693) |
0.1 | 0.1 | GO:0072201 | negative regulation of mesenchymal cell proliferation(GO:0072201) |
0.1 | 0.6 | GO:0045329 | amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329) |
0.1 | 0.6 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
0.1 | 0.3 | GO:0001778 | plasma membrane repair(GO:0001778) |
0.1 | 0.5 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
0.1 | 0.2 | GO:0046102 | nicotinamide riboside catabolic process(GO:0006738) inosine metabolic process(GO:0046102) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638) |
0.1 | 0.2 | GO:0019695 | choline metabolic process(GO:0019695) |
0.1 | 0.2 | GO:0060729 | negative regulation of interleukin-23 production(GO:0032707) intestinal epithelial structure maintenance(GO:0060729) |
0.1 | 0.2 | GO:0035461 | vitamin transmembrane transport(GO:0035461) |
0.1 | 0.2 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
0.1 | 0.2 | GO:0001692 | histamine metabolic process(GO:0001692) |
0.0 | 0.1 | GO:1901419 | regulation of response to alcohol(GO:1901419) |
0.0 | 0.3 | GO:0000050 | urea cycle(GO:0000050) |
0.0 | 0.8 | GO:0042730 | fibrinolysis(GO:0042730) |
0.0 | 1.8 | GO:0060338 | regulation of type I interferon-mediated signaling pathway(GO:0060338) |
0.0 | 0.4 | GO:0015886 | heme transport(GO:0015886) |
0.0 | 1.3 | GO:0006730 | one-carbon metabolic process(GO:0006730) |
0.0 | 0.3 | GO:0006264 | mitochondrial DNA replication(GO:0006264) |
0.0 | 0.4 | GO:0010658 | striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667) |
0.0 | 0.9 | GO:0045745 | positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745) |
0.0 | 0.1 | GO:0035025 | positive regulation of Rho protein signal transduction(GO:0035025) |
0.0 | 0.8 | GO:0007172 | signal complex assembly(GO:0007172) |
0.0 | 0.1 | GO:0030997 | regulation of centriole-centriole cohesion(GO:0030997) |
0.0 | 0.4 | GO:0051014 | actin filament severing(GO:0051014) |
0.0 | 0.6 | GO:0008210 | estrogen metabolic process(GO:0008210) |
0.0 | 0.0 | GO:0019627 | urea metabolic process(GO:0019627) |
0.0 | 0.1 | GO:0006726 | eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474) |
0.0 | 0.1 | GO:0051066 | dihydrobiopterin metabolic process(GO:0051066) |
0.0 | 0.1 | GO:0072205 | collecting duct development(GO:0072044) metanephric collecting duct development(GO:0072205) |
0.0 | 1.1 | GO:0050909 | sensory perception of taste(GO:0050909) |
0.0 | 0.5 | GO:0035024 | negative regulation of Rho protein signal transduction(GO:0035024) |
0.0 | 0.1 | GO:0045750 | obsolete positive regulation of S phase of mitotic cell cycle(GO:0045750) |
0.0 | 0.2 | GO:0060219 | camera-type eye photoreceptor cell differentiation(GO:0060219) |
0.0 | 0.3 | GO:0060907 | cGMP-mediated signaling(GO:0019934) regulation of phagocytosis, engulfment(GO:0060099) positive regulation of phagocytosis, engulfment(GO:0060100) positive regulation of macrophage cytokine production(GO:0060907) regulation of membrane invagination(GO:1905153) positive regulation of membrane invagination(GO:1905155) |
0.0 | 0.4 | GO:0046697 | decidualization(GO:0046697) |
0.0 | 0.3 | GO:0050892 | intestinal absorption(GO:0050892) |
0.0 | 0.2 | GO:0046968 | peptide antigen transport(GO:0046968) |
0.0 | 0.7 | GO:0030574 | collagen catabolic process(GO:0030574) |
0.0 | 0.1 | GO:0046621 | negative regulation of organ growth(GO:0046621) |
0.0 | 0.5 | GO:0006071 | glycerol metabolic process(GO:0006071) |
0.0 | 0.1 | GO:0034720 | histone H3-K4 demethylation(GO:0034720) |
0.0 | 0.1 | GO:0043006 | activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006) |
0.0 | 0.3 | GO:0002347 | response to tumor cell(GO:0002347) |
0.0 | 0.3 | GO:0006787 | porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149) |
0.0 | 0.1 | GO:0010727 | negative regulation of hydrogen peroxide metabolic process(GO:0010727) |
0.0 | 0.1 | GO:0018125 | peptidyl-cysteine methylation(GO:0018125) |
0.0 | 0.1 | GO:0002523 | leukocyte migration involved in inflammatory response(GO:0002523) |
0.0 | 0.4 | GO:1900047 | negative regulation of blood coagulation(GO:0030195) negative regulation of wound healing(GO:0061045) negative regulation of hemostasis(GO:1900047) |
0.0 | 0.1 | GO:0050955 | thermoception(GO:0050955) |
0.0 | 0.1 | GO:0050747 | positive regulation of lipoprotein metabolic process(GO:0050747) |
0.0 | 0.2 | GO:0006654 | positive regulation of cytokine-mediated signaling pathway(GO:0001961) phosphatidic acid biosynthetic process(GO:0006654) |
0.0 | 0.1 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
0.0 | 0.1 | GO:0034442 | plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161) |
0.0 | 0.8 | GO:0006699 | bile acid biosynthetic process(GO:0006699) |
0.0 | 0.1 | GO:0018874 | benzoate metabolic process(GO:0018874) |
0.0 | 0.2 | GO:0006013 | mannose metabolic process(GO:0006013) |
0.0 | 0.9 | GO:0030216 | keratinocyte differentiation(GO:0030216) |
0.0 | 3.1 | GO:0010951 | negative regulation of endopeptidase activity(GO:0010951) |
0.0 | 0.1 | GO:0042519 | tyrosine phosphorylation of Stat4 protein(GO:0042504) regulation of tyrosine phosphorylation of Stat4 protein(GO:0042519) positive regulation of tyrosine phosphorylation of Stat4 protein(GO:0042520) |
0.0 | 0.2 | GO:0016998 | cell wall macromolecule catabolic process(GO:0016998) |
0.0 | 0.1 | GO:0006422 | aspartyl-tRNA aminoacylation(GO:0006422) |
0.0 | 0.1 | GO:0072284 | visceral serous pericardium development(GO:0061032) S-shaped body morphogenesis(GO:0072050) metanephric S-shaped body morphogenesis(GO:0072284) |
0.0 | 0.1 | GO:1903960 | negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192) |
0.0 | 0.2 | GO:0043415 | positive regulation of skeletal muscle tissue regeneration(GO:0043415) regulation of skeletal muscle tissue regeneration(GO:0043416) |
0.0 | 0.3 | GO:1904893 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
0.0 | 0.2 | GO:0006525 | arginine metabolic process(GO:0006525) |
0.0 | 0.1 | GO:0042986 | positive regulation of amyloid precursor protein biosynthetic process(GO:0042986) |
0.0 | 0.3 | GO:0050872 | white fat cell differentiation(GO:0050872) |
0.0 | 0.3 | GO:0035329 | hippo signaling(GO:0035329) |
0.0 | 0.1 | GO:0009822 | alkaloid catabolic process(GO:0009822) |
0.0 | 0.2 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
0.0 | 0.1 | GO:0033522 | histone H2A ubiquitination(GO:0033522) |
0.0 | 0.1 | GO:0003215 | cardiac right ventricle morphogenesis(GO:0003215) |
0.0 | 0.1 | GO:0035120 | post-embryonic appendage morphogenesis(GO:0035120) |
0.0 | 0.1 | GO:0006642 | triglyceride mobilization(GO:0006642) |
0.0 | 0.4 | GO:0008206 | bile acid metabolic process(GO:0008206) |
0.0 | 0.1 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
0.0 | 0.7 | GO:0030837 | negative regulation of actin filament polymerization(GO:0030837) |
0.0 | 0.3 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
0.0 | 0.1 | GO:0030277 | epithelial structure maintenance(GO:0010669) maintenance of gastrointestinal epithelium(GO:0030277) |
0.0 | 0.1 | GO:0070634 | transepithelial ammonium transport(GO:0070634) |
0.0 | 0.1 | GO:0007549 | dosage compensation(GO:0007549) |
0.0 | 0.1 | GO:0051289 | protein homotetramerization(GO:0051289) |
0.0 | 0.1 | GO:0010700 | negative regulation of norepinephrine secretion(GO:0010700) |
0.0 | 0.1 | GO:0001845 | phagolysosome assembly(GO:0001845) post-embryonic organ morphogenesis(GO:0048563) phagosome maturation(GO:0090382) |
0.0 | 0.2 | GO:0060216 | definitive hemopoiesis(GO:0060216) |
0.0 | 0.1 | GO:0043267 | negative regulation of potassium ion transport(GO:0043267) |
0.0 | 0.2 | GO:0008631 | intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) cell death in response to oxidative stress(GO:0036473) |
0.0 | 0.1 | GO:0045056 | transcytosis(GO:0045056) |
0.0 | 0.1 | GO:0007206 | phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) |
0.0 | 0.0 | GO:2000008 | regulation of protein localization to cell surface(GO:2000008) |
0.0 | 0.4 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
0.0 | 0.1 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
0.0 | 0.2 | GO:0006862 | nucleotide transport(GO:0006862) |
0.0 | 0.0 | GO:0034036 | purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428) |
0.0 | 0.1 | GO:0071318 | cellular response to ATP(GO:0071318) |
0.0 | 0.2 | GO:0048261 | negative regulation of receptor-mediated endocytosis(GO:0048261) |
0.0 | 0.1 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
0.0 | 0.1 | GO:0048147 | negative regulation of fibroblast proliferation(GO:0048147) |
0.0 | 0.1 | GO:0042517 | positive regulation of tyrosine phosphorylation of Stat3 protein(GO:0042517) |
0.0 | 0.0 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
0.0 | 0.1 | GO:0051294 | establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294) |
0.0 | 0.2 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
0.0 | 0.2 | GO:0009629 | response to gravity(GO:0009629) |
0.0 | 0.2 | GO:0009812 | flavonoid metabolic process(GO:0009812) |
0.0 | 0.1 | GO:0002885 | positive regulation of hypersensitivity(GO:0002885) |
0.0 | 0.0 | GO:0032621 | interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661) |
0.0 | 0.1 | GO:0006553 | lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554) |
0.0 | 0.0 | GO:0006577 | amino-acid betaine metabolic process(GO:0006577) carnitine metabolic process(GO:0009437) |
0.0 | 0.2 | GO:0035036 | binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) |
0.0 | 0.1 | GO:0017183 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
0.0 | 0.1 | GO:0045059 | positive thymic T cell selection(GO:0045059) |
0.0 | 0.0 | GO:0051083 | 'de novo' cotranslational protein folding(GO:0051083) |
0.0 | 0.1 | GO:0007342 | fusion of sperm to egg plasma membrane(GO:0007342) |
0.0 | 0.1 | GO:0042769 | DNA damage response, detection of DNA damage(GO:0042769) |
0.0 | 0.1 | GO:0070682 | proteasome regulatory particle assembly(GO:0070682) |
0.0 | 0.0 | GO:0009103 | lipopolysaccharide biosynthetic process(GO:0009103) |
0.0 | 0.1 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
0.0 | 0.3 | GO:0015804 | neutral amino acid transport(GO:0015804) |
0.0 | 0.1 | GO:0042940 | D-amino acid transport(GO:0042940) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
0.0 | 0.0 | GO:0070265 | necrotic cell death(GO:0070265) |
0.0 | 0.1 | GO:0061339 | establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339) |
0.0 | 0.1 | GO:0046668 | regulation of retinal cell programmed cell death(GO:0046668) |
0.0 | 0.3 | GO:0042554 | superoxide anion generation(GO:0042554) |
0.0 | 0.1 | GO:0010226 | response to lithium ion(GO:0010226) |
0.0 | 0.1 | GO:0055015 | ventricular cardiac muscle cell development(GO:0055015) |
0.0 | 0.1 | GO:0017121 | phospholipid scrambling(GO:0017121) |
0.0 | 0.2 | GO:0045104 | intermediate filament cytoskeleton organization(GO:0045104) |
0.0 | 0.6 | GO:0061025 | membrane fusion(GO:0061025) |
0.0 | 0.0 | GO:0060423 | foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047) iris morphogenesis(GO:0061072) cornea development in camera-type eye(GO:0061303) |
0.0 | 0.1 | GO:0048388 | endosomal lumen acidification(GO:0048388) |
0.0 | 0.1 | GO:0015871 | choline transport(GO:0015871) |
0.0 | 0.2 | GO:0006700 | C21-steroid hormone biosynthetic process(GO:0006700) |
0.0 | 0.1 | GO:0046519 | sphingoid metabolic process(GO:0046519) |
0.0 | 0.1 | GO:0051546 | keratinocyte migration(GO:0051546) |
0.0 | 0.2 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 0.9 | GO:0009986 | cell surface(GO:0009986) |
0.3 | 0.9 | GO:0005610 | laminin-5 complex(GO:0005610) |
0.1 | 1.6 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
0.1 | 3.7 | GO:0001533 | cornified envelope(GO:0001533) |
0.1 | 2.2 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
0.1 | 0.8 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
0.1 | 1.5 | GO:0005606 | laminin-1 complex(GO:0005606) |
0.1 | 0.5 | GO:0005916 | fascia adherens(GO:0005916) |
0.1 | 0.7 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.1 | 1.0 | GO:0005833 | hemoglobin complex(GO:0005833) |
0.1 | 0.2 | GO:0071062 | alphav-beta3 integrin-vitronectin complex(GO:0071062) |
0.1 | 0.4 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
0.1 | 0.1 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
0.1 | 0.1 | GO:0016235 | aggresome(GO:0016235) |
0.1 | 0.2 | GO:0032585 | multivesicular body membrane(GO:0032585) |
0.1 | 0.5 | GO:0005766 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
0.0 | 0.1 | GO:0005726 | perichromatin fibrils(GO:0005726) |
0.0 | 0.2 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
0.0 | 0.2 | GO:0045179 | apical cortex(GO:0045179) |
0.0 | 0.5 | GO:0042627 | chylomicron(GO:0042627) |
0.0 | 0.2 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
0.0 | 0.1 | GO:0030125 | clathrin vesicle coat(GO:0030125) |
0.0 | 0.1 | GO:0000776 | kinetochore(GO:0000776) |
0.0 | 0.1 | GO:0001740 | Barr body(GO:0001740) |
0.0 | 0.1 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
0.0 | 0.2 | GO:0030056 | hemidesmosome(GO:0030056) |
0.0 | 0.0 | GO:0005889 | hydrogen:potassium-exchanging ATPase complex(GO:0005889) |
0.0 | 0.8 | GO:0005776 | autophagosome(GO:0005776) |
0.0 | 0.3 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
0.0 | 0.1 | GO:0005900 | oncostatin-M receptor complex(GO:0005900) |
0.0 | 0.1 | GO:0033162 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
0.0 | 0.4 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
0.0 | 6.8 | GO:0005792 | obsolete microsome(GO:0005792) |
0.0 | 0.3 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
0.0 | 0.3 | GO:0030122 | AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128) |
0.0 | 0.3 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
0.0 | 0.2 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
0.0 | 0.1 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
0.0 | 0.1 | GO:0072536 | interleukin-23 receptor complex(GO:0072536) |
0.0 | 0.2 | GO:0005577 | fibrinogen complex(GO:0005577) |
0.0 | 0.1 | GO:0016272 | prefoldin complex(GO:0016272) |
0.0 | 0.0 | GO:0000802 | transverse filament(GO:0000802) |
0.0 | 0.1 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
0.0 | 0.1 | GO:0031143 | pseudopodium(GO:0031143) |
0.0 | 0.1 | GO:0042382 | paraspeckles(GO:0042382) |
0.0 | 0.4 | GO:0005844 | polysome(GO:0005844) |
0.0 | 0.1 | GO:0032144 | 4-aminobutyrate transaminase complex(GO:0032144) |
0.0 | 0.7 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
0.0 | 0.1 | GO:0008540 | proteasome regulatory particle, base subcomplex(GO:0008540) |
0.0 | 2.6 | GO:0005925 | focal adhesion(GO:0005925) |
0.0 | 0.2 | GO:0030914 | STAGA complex(GO:0030914) |
0.0 | 0.5 | GO:0045095 | keratin filament(GO:0045095) |
0.0 | 0.0 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
0.0 | 0.3 | GO:0016328 | lateral plasma membrane(GO:0016328) |
0.0 | 0.2 | GO:0005796 | Golgi lumen(GO:0005796) |
0.0 | 0.4 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
0.0 | 0.1 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
0.0 | 0.4 | GO:0031526 | brush border membrane(GO:0031526) |
0.0 | 0.0 | GO:0005839 | proteasome core complex(GO:0005839) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 1.8 | GO:0047718 | indanol dehydrogenase activity(GO:0047718) |
0.4 | 1.6 | GO:0019834 | phospholipase A2 inhibitor activity(GO:0019834) |
0.4 | 1.1 | GO:0047115 | trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115) |
0.4 | 1.9 | GO:0060961 | phospholipase D inhibitor activity(GO:0060961) |
0.3 | 1.3 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
0.3 | 1.0 | GO:0016211 | glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880) |
0.2 | 0.2 | GO:0047042 | androsterone dehydrogenase (B-specific) activity(GO:0047042) |
0.2 | 6.8 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
0.2 | 0.6 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
0.1 | 0.4 | GO:0004833 | tryptophan 2,3-dioxygenase activity(GO:0004833) |
0.1 | 0.9 | GO:0005132 | type I interferon receptor binding(GO:0005132) |
0.1 | 0.6 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
0.1 | 1.1 | GO:0008527 | taste receptor activity(GO:0008527) |
0.1 | 0.3 | GO:0004797 | thymidine kinase activity(GO:0004797) |
0.1 | 0.2 | GO:0047006 | 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) |
0.1 | 3.0 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.1 | 0.4 | GO:0042910 | xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910) |
0.1 | 0.4 | GO:0003796 | lysozyme activity(GO:0003796) |
0.1 | 0.4 | GO:0005026 | transforming growth factor beta receptor activity, type II(GO:0005026) |
0.1 | 1.4 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
0.1 | 1.0 | GO:0005344 | oxygen transporter activity(GO:0005344) |
0.1 | 0.4 | GO:0080030 | methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032) |
0.1 | 0.6 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
0.1 | 0.4 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.1 | 0.2 | GO:0004613 | phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613) |
0.1 | 0.3 | GO:0019862 | IgA binding(GO:0019862) |
0.1 | 0.3 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
0.1 | 0.4 | GO:0033989 | 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) |
0.1 | 0.4 | GO:0019871 | sodium channel inhibitor activity(GO:0019871) |
0.1 | 0.2 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
0.1 | 0.3 | GO:0051996 | farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996) |
0.1 | 0.3 | GO:0018685 | alkane 1-monooxygenase activity(GO:0018685) |
0.1 | 0.2 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
0.1 | 0.3 | GO:0034711 | inhibin binding(GO:0034711) |
0.1 | 0.2 | GO:0004731 | purine-nucleoside phosphorylase activity(GO:0004731) |
0.1 | 0.5 | GO:1901567 | icosanoid binding(GO:0050542) icosatetraenoic acid binding(GO:0050543) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567) |
0.1 | 0.5 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
0.1 | 0.2 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
0.1 | 0.5 | GO:0016595 | glutamate binding(GO:0016595) |
0.0 | 0.1 | GO:0004948 | calcitonin receptor activity(GO:0004948) |
0.0 | 0.3 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
0.0 | 0.6 | GO:0043274 | phospholipase binding(GO:0043274) |
0.0 | 0.4 | GO:0042153 | obsolete RPTP-like protein binding(GO:0042153) |
0.0 | 0.6 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
0.0 | 0.5 | GO:0015643 | toxic substance binding(GO:0015643) |
0.0 | 0.4 | GO:0016018 | cyclosporin A binding(GO:0016018) |
0.0 | 0.9 | GO:0008143 | poly(A) binding(GO:0008143) |
0.0 | 0.4 | GO:0030297 | transmembrane receptor protein tyrosine kinase activator activity(GO:0030297) |
0.0 | 0.2 | GO:0034597 | phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) |
0.0 | 0.4 | GO:0046934 | obsolete inositol or phosphatidylinositol kinase activity(GO:0004428) phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813) |
0.0 | 0.3 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
0.0 | 0.5 | GO:0005243 | gap junction channel activity(GO:0005243) |
0.0 | 0.2 | GO:0003956 | NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956) |
0.0 | 0.2 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
0.0 | 0.2 | GO:0033265 | acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265) |
0.0 | 0.1 | GO:0004756 | selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781) |
0.0 | 0.9 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
0.0 | 0.2 | GO:0004910 | interleukin-1, Type II, blocking receptor activity(GO:0004910) |
0.0 | 0.3 | GO:0004969 | histamine receptor activity(GO:0004969) |
0.0 | 0.7 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.0 | 3.6 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.0 | 0.2 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.0 | 0.1 | GO:0036041 | long-chain fatty acid binding(GO:0036041) |
0.0 | 0.3 | GO:0031419 | cobalamin binding(GO:0031419) |
0.0 | 0.2 | GO:0090482 | vitamin transmembrane transporter activity(GO:0090482) |
0.0 | 0.1 | GO:0032453 | histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648) |
0.0 | 0.7 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
0.0 | 0.3 | GO:0019826 | oxygen sensor activity(GO:0019826) |
0.0 | 0.6 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.0 | 0.1 | GO:0005412 | glucose:sodium symporter activity(GO:0005412) |
0.0 | 0.9 | GO:0005523 | tropomyosin binding(GO:0005523) |
0.0 | 0.3 | GO:0047760 | butyrate-CoA ligase activity(GO:0047760) |
0.0 | 0.1 | GO:0004608 | phosphatidylethanolamine N-methyltransferase activity(GO:0004608) |
0.0 | 0.2 | GO:0046790 | virion binding(GO:0046790) |
0.0 | 0.1 | GO:0015562 | efflux transmembrane transporter activity(GO:0015562) |
0.0 | 0.1 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
0.0 | 0.4 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
0.0 | 0.2 | GO:0047894 | flavonol 3-sulfotransferase activity(GO:0047894) |
0.0 | 0.1 | GO:0042289 | MHC class II protein binding(GO:0042289) |
0.0 | 0.2 | GO:0008020 | G-protein coupled photoreceptor activity(GO:0008020) |
0.0 | 0.2 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
0.0 | 0.1 | GO:0046403 | polynucleotide 3'-phosphatase activity(GO:0046403) |
0.0 | 0.1 | GO:0003960 | NADPH:quinone reductase activity(GO:0003960) |
0.0 | 0.1 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
0.0 | 0.1 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
0.0 | 0.1 | GO:0019763 | immunoglobulin receptor activity(GO:0019763) |
0.0 | 0.1 | GO:0004566 | beta-glucuronidase activity(GO:0004566) |
0.0 | 0.2 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) |
0.0 | 0.3 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
0.0 | 0.2 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
0.0 | 0.1 | GO:0030492 | hemoglobin binding(GO:0030492) |
0.0 | 0.1 | GO:0042132 | fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132) |
0.0 | 0.1 | GO:0004844 | uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506) |
0.0 | 0.1 | GO:0004815 | aspartate-tRNA ligase activity(GO:0004815) |
0.0 | 0.1 | GO:0035240 | dopamine binding(GO:0035240) |
0.0 | 0.1 | GO:0034875 | oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875) |
0.0 | 0.3 | GO:0015924 | mannosyl-oligosaccharide mannosidase activity(GO:0015924) |
0.0 | 0.4 | GO:0017153 | sodium:dicarboxylate symporter activity(GO:0017153) |
0.0 | 0.1 | GO:0004924 | oncostatin-M receptor activity(GO:0004924) |
0.0 | 0.1 | GO:0016681 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
0.0 | 0.1 | GO:0017057 | glucose-6-phosphate dehydrogenase activity(GO:0004345) 6-phosphogluconolactonase activity(GO:0017057) |
0.0 | 0.1 | GO:0004925 | prolactin receptor activity(GO:0004925) |
0.0 | 0.1 | GO:0004663 | Rab geranylgeranyltransferase activity(GO:0004663) |
0.0 | 0.1 | GO:0009384 | N-acylmannosamine kinase activity(GO:0009384) |
0.0 | 0.1 | GO:0004461 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) lactose synthase activity(GO:0004461) |
0.0 | 0.1 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
0.0 | 0.3 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
0.0 | 0.1 | GO:0030506 | ankyrin binding(GO:0030506) |
0.0 | 0.1 | GO:0030197 | extracellular matrix constituent, lubricant activity(GO:0030197) |
0.0 | 0.2 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
0.0 | 0.1 | GO:0001632 | leukotriene B4 receptor activity(GO:0001632) |
0.0 | 0.1 | GO:0042020 | interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020) |
0.0 | 0.1 | GO:0031686 | A1 adenosine receptor binding(GO:0031686) |
0.0 | 0.2 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617) |
0.0 | 0.1 | GO:0047708 | biotinidase activity(GO:0047708) |
0.0 | 0.2 | GO:0030247 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
0.0 | 0.1 | GO:0034056 | estrogen response element binding(GO:0034056) |
0.0 | 0.5 | GO:0019003 | GDP binding(GO:0019003) |
0.0 | 0.1 | GO:0051378 | serotonin binding(GO:0051378) |
0.0 | 0.1 | GO:0008649 | rRNA methyltransferase activity(GO:0008649) |
0.0 | 0.0 | GO:0004609 | phosphatidylserine decarboxylase activity(GO:0004609) |
0.0 | 0.1 | GO:0004064 | arylesterase activity(GO:0004064) |
0.0 | 0.1 | GO:0042808 | obsolete neuronal Cdc2-like kinase binding(GO:0042808) |
0.0 | 0.0 | GO:0008174 | mRNA methyltransferase activity(GO:0008174) |
0.0 | 0.0 | GO:0004781 | adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781) |
0.0 | 0.1 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
0.0 | 0.0 | GO:0016803 | ether hydrolase activity(GO:0016803) hepoxilin-epoxide hydrolase activity(GO:0047977) arachidonate 15-lipoxygenase activity(GO:0050473) |
0.0 | 0.1 | GO:0015184 | L-cystine transmembrane transporter activity(GO:0015184) |
0.0 | 0.1 | GO:0031701 | angiotensin receptor binding(GO:0031701) |
0.0 | 0.2 | GO:0005338 | nucleotide-sugar transmembrane transporter activity(GO:0005338) |
0.0 | 0.0 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
0.0 | 0.4 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.0 | 0.3 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
0.0 | 0.4 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
0.0 | 0.0 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
0.0 | 0.1 | GO:0005123 | death receptor binding(GO:0005123) |
0.0 | 0.1 | GO:0032145 | 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298) |
0.0 | 0.2 | GO:0047617 | acyl-CoA hydrolase activity(GO:0047617) |
0.0 | 0.1 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
0.0 | 0.1 | GO:0005499 | vitamin D binding(GO:0005499) |
0.0 | 0.0 | GO:0008900 | hydrogen:potassium-exchanging ATPase activity(GO:0008900) |
0.0 | 0.4 | GO:0019843 | rRNA binding(GO:0019843) |
0.0 | 0.1 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
0.0 | 0.1 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
0.0 | 0.2 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
0.0 | 0.1 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
0.0 | 2.1 | GO:0030674 | protein binding, bridging(GO:0030674) |
0.0 | 0.1 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
0.0 | 0.1 | GO:0042974 | retinoic acid receptor binding(GO:0042974) |
0.0 | 0.1 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
0.0 | 0.3 | GO:0008373 | sialyltransferase activity(GO:0008373) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.4 | SA_PROGRAMMED_CELL_DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
0.0 | 0.7 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
0.0 | 0.6 | ST_GA13_PATHWAY | G alpha 13 Pathway |