Motif ID: HOXC8

Z-value: 0.972


Transcription factors associated with HOXC8:

Gene SymbolEntrez IDGene Name
HOXC8 ENSG00000037965.4 HOXC8



Activity profile for motif HOXC8.

activity profile for motif HOXC8


Sorted Z-values histogram for motif HOXC8

Sorted Z-values for motif HOXC8



Network of associatons between targets according to the STRING database.



First level regulatory network of HOXC8

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_79472673 1.590 ENST00000264908.6
ANXA3
annexin A3
chr10_+_47746929 1.185 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
ANXA8L2



AL603965.1
annexin A8-like 2



Protein LOC100996760
chr10_-_5046042 1.145 ENST00000421196.3
ENST00000455190.1
AKR1C2

aldo-keto reductase family 1, member C2

chr3_-_149095652 1.046 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chr4_-_90757364 1.037 ENST00000508895.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr18_+_61445007 1.000 ENST00000447428.1
ENST00000546027.1
SERPINB7

serpin peptidase inhibitor, clade B (ovalbumin), member 7

chr10_-_47173994 0.977 ENST00000414655.2
ENST00000545298.1
ENST00000359178.4
ENST00000358140.4
ENST00000503031.1
ANXA8L1



LINC00842
annexin A8-like 1



long intergenic non-protein coding RNA 842
chr18_+_21269404 0.976 ENST00000313654.9
LAMA3
laminin, alpha 3
chr10_+_48255253 0.953 ENST00000357718.4
ENST00000344416.5
ENST00000456111.2
ENST00000374258.3
ANXA8


AL591684.1
annexin A8


Protein LOC100996760
chrX_-_38080077 0.938 ENST00000378533.3
ENST00000544439.1
ENST00000432886.2
ENST00000538295.1
SRPX



sushi-repeat containing protein, X-linked



chr1_-_209824643 0.900 ENST00000391911.1
ENST00000415782.1
LAMB3

laminin, beta 3

chr12_+_19358228 0.885 ENST00000424268.1
ENST00000543806.1
PLEKHA5

pleckstrin homology domain containing, family A member 5

chr4_-_90756769 0.844 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
SNCA


synuclein, alpha (non A4 component of amyloid precursor)


chr11_-_102651343 0.817 ENST00000279441.4
ENST00000539681.1
MMP10

matrix metallopeptidase 10 (stromelysin 2)

chr15_-_63674034 0.744 ENST00000344366.3
ENST00000422263.2
CA12

carbonic anhydrase XII

chr6_+_7541845 0.737 ENST00000418664.2
DSP
desmoplakin
chr2_+_234621551 0.736 ENST00000373414.3
ENST00000608381.1
UGT1A5
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A5
UDP glucuronosyltransferase 1 family, polypeptide A8
chr1_+_152956549 0.723 ENST00000307122.2
SPRR1A
small proline-rich protein 1A
chr9_+_470288 0.715 ENST00000382303.1
KANK1
KN motif and ankyrin repeat domains 1
chr4_+_69681710 0.692 ENST00000265403.7
ENST00000458688.2
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr10_+_5135981 0.687 ENST00000380554.3
AKR1C3
aldo-keto reductase family 1, member C3
chr8_+_30244580 0.677 ENST00000523115.1
ENST00000519647.1
RBPMS

RNA binding protein with multiple splicing

chr18_+_61143994 0.675 ENST00000382771.4
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr8_+_104310661 0.675 ENST00000522566.1
FZD6
frizzled family receptor 6
chr18_+_61554932 0.662 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
SERPINB2


serpin peptidase inhibitor, clade B (ovalbumin), member 2


chr18_+_21529811 0.647 ENST00000588004.1
LAMA3
laminin, alpha 3
chr10_+_5005445 0.626 ENST00000380872.4
AKR1C1
aldo-keto reductase family 1, member C1
chr10_+_54074033 0.624 ENST00000373970.3
DKK1
dickkopf WNT signaling pathway inhibitor 1
chr2_+_192109911 0.624 ENST00000418908.1
ENST00000339514.4
ENST00000392318.3
MYO1B


myosin IB


chr11_+_101983176 0.623 ENST00000524575.1
YAP1
Yes-associated protein 1
chr5_+_135385202 0.611 ENST00000514554.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr9_-_21305312 0.606 ENST00000259555.4
IFNA5
interferon, alpha 5
chr4_-_70080449 0.600 ENST00000446444.1
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr3_+_118905564 0.594 ENST00000460625.1
UPK1B
uroplakin 1B
chr8_+_30300119 0.555 ENST00000520191.1
RBPMS
RNA binding protein with multiple splicing
chr15_-_63674218 0.551 ENST00000178638.3
CA12
carbonic anhydrase XII
chr6_-_169654139 0.540 ENST00000366787.3
THBS2
thrombospondin 2
chr1_+_152957707 0.539 ENST00000368762.1
SPRR1A
small proline-rich protein 1A
chr7_+_134528635 0.531 ENST00000445569.2
CALD1
caldesmon 1
chr6_+_121756809 0.527 ENST00000282561.3
GJA1
gap junction protein, alpha 1, 43kDa
chr4_+_74275057 0.524 ENST00000511370.1
ALB
albumin
chr1_-_182360918 0.523 ENST00000339526.4
GLUL
glutamate-ammonia ligase
chr6_+_123110465 0.518 ENST00000539041.1
SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr11_+_59480899 0.511 ENST00000300150.7
STX3
syntaxin 3
chr17_-_64216748 0.507 ENST00000585162.1
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr2_+_20646824 0.504 ENST00000272233.4
RHOB
ras homolog family member B
chr2_+_211342432 0.503 ENST00000430249.2
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr1_-_182361327 0.499 ENST00000331872.6
ENST00000311223.5
GLUL

glutamate-ammonia ligase

chr2_+_102456277 0.493 ENST00000421882.1
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr8_-_19459993 0.492 ENST00000454498.2
ENST00000520003.1
CSGALNACT1

chondroitin sulfate N-acetylgalactosaminyltransferase 1

chr19_-_51456321 0.482 ENST00000391809.2
KLK5
kallikrein-related peptidase 5
chr4_+_69962212 0.480 ENST00000508661.1
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr10_+_5005598 0.474 ENST00000442997.1
AKR1C1
aldo-keto reductase family 1, member C1
chr8_-_141774467 0.470 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
PTK2


protein tyrosine kinase 2


chr8_-_13134045 0.466 ENST00000512044.2
DLC1
deleted in liver cancer 1
chr12_-_28124903 0.461 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
PTHLH


parathyroid hormone-like hormone


chr4_+_69962185 0.455 ENST00000305231.7
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr6_-_2962331 0.448 ENST00000380524.1
SERPINB6
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr19_-_51456344 0.447 ENST00000336334.3
ENST00000593428.1
KLK5

kallikrein-related peptidase 5

chr4_+_169418195 0.446 ENST00000261509.6
ENST00000335742.7
PALLD

palladin, cytoskeletal associated protein

chr8_+_39770803 0.445 ENST00000518237.1
IDO1
indoleamine 2,3-dioxygenase 1
chr12_-_10978957 0.438 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr11_-_5271122 0.435 ENST00000330597.3
HBG1
hemoglobin, gamma A
chr6_+_151646800 0.434 ENST00000354675.6
AKAP12
A kinase (PRKA) anchor protein 12
chr11_+_57520715 0.432 ENST00000524630.1
ENST00000529919.1
ENST00000399039.4
ENST00000533189.1
CTNND1



catenin (cadherin-associated protein), delta 1



chr21_-_43187231 0.427 ENST00000332512.3
ENST00000352483.2
RIPK4

receptor-interacting serine-threonine kinase 4

chr20_+_19867150 0.426 ENST00000255006.6
RIN2
Ras and Rab interactor 2
chr5_-_122372354 0.425 ENST00000306442.4
PPIC
peptidylprolyl isomerase C (cyclophilin C)
chr2_-_106054952 0.424 ENST00000336660.5
ENST00000393352.3
ENST00000607522.1
FHL2


four and a half LIM domains 2


chr9_-_21202204 0.423 ENST00000239347.3
IFNA7
interferon, alpha 7
chr12_-_53320245 0.412 ENST00000552150.1
KRT8
keratin 8
chr18_+_55862622 0.409 ENST00000456173.2
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr11_-_321050 0.406 ENST00000399808.4
IFITM3
interferon induced transmembrane protein 3
chr7_-_139763521 0.405 ENST00000263549.3
PARP12
poly (ADP-ribose) polymerase family, member 12
chrY_+_2709527 0.404 ENST00000250784.8
RPS4Y1
ribosomal protein S4, Y-linked 1
chr1_+_77333117 0.402 ENST00000477717.1
ST6GALNAC5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr6_-_134639180 0.393 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr10_-_69597915 0.382 ENST00000225171.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr8_+_31497271 0.381 ENST00000520407.1
NRG1
neuregulin 1
chr2_+_234600253 0.378 ENST00000373424.1
ENST00000441351.1
UGT1A6

UDP glucuronosyltransferase 1 family, polypeptide A6

chr1_-_153066998 0.377 ENST00000368750.3
SPRR2E
small proline-rich protein 2E
chr4_-_89080003 0.376 ENST00000237612.3
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr2_+_106468204 0.375 ENST00000425756.1
ENST00000393349.2
NCK2

NCK adaptor protein 2

chr7_+_107224364 0.374 ENST00000491150.1
BCAP29
B-cell receptor-associated protein 29
chr12_+_69742121 0.373 ENST00000261267.2
ENST00000549690.1
ENST00000548839.1
LYZ


lysozyme


chr3_+_30647994 0.371 ENST00000295754.5
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr19_-_10697895 0.369 ENST00000591240.1
ENST00000589684.1
ENST00000591676.1
ENST00000250244.6
ENST00000590923.1
AP1M2




adaptor-related protein complex 1, mu 2 subunit




chr5_-_55412774 0.368 ENST00000434982.2
ANKRD55
ankyrin repeat domain 55
chr1_-_110283138 0.358 ENST00000256594.3
GSTM3
glutathione S-transferase mu 3 (brain)
chr20_-_14318248 0.358 ENST00000378053.3
ENST00000341420.4
FLRT3

fibronectin leucine rich transmembrane protein 3

chr11_-_5276008 0.357 ENST00000336906.4
HBG2
hemoglobin, gamma G
chrX_+_15525426 0.355 ENST00000342014.6
BMX
BMX non-receptor tyrosine kinase
chr2_+_234602305 0.352 ENST00000406651.1
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr11_+_12766583 0.348 ENST00000361985.2
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr1_-_153113927 0.346 ENST00000368752.4
SPRR2B
small proline-rich protein 2B
chr2_+_234580525 0.343 ENST00000609637.1
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr19_+_45449301 0.340 ENST00000591597.1
APOC2
apolipoprotein C-II
chr14_-_105420241 0.339 ENST00000557457.1
AHNAK2
AHNAK nucleoprotein 2
chr6_+_131894284 0.338 ENST00000368087.3
ENST00000356962.2
ARG1

arginase 1

chr11_-_59633951 0.330 ENST00000257264.3
TCN1
transcobalamin I (vitamin B12 binding protein, R binder family)
chr4_+_88896819 0.328 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
SPP1



secreted phosphoprotein 1



chr18_-_21891460 0.327 ENST00000357041.4
OSBPL1A
oxysterol binding protein-like 1A
chr2_+_138722028 0.326 ENST00000280096.5
HNMT
histamine N-methyltransferase
chr2_+_234580499 0.326 ENST00000354728.4
UGT1A9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr19_-_47291843 0.325 ENST00000542575.2
SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr5_-_150948414 0.325 ENST00000261800.5
FAT2
FAT atypical cadherin 2
chr12_-_44200146 0.321 ENST00000395510.2
ENST00000325127.4
TWF1

twinfilin actin-binding protein 1

chr1_+_144173162 0.314 ENST00000356801.6
NBPF8
neuroblastoma breakpoint family, member 8
chr10_+_5488564 0.305 ENST00000449083.1
ENST00000380359.3
NET1

neuroepithelial cell transforming 1

chr4_+_175204818 0.301 ENST00000503780.1
CEP44
centrosomal protein 44kDa
chr1_-_153085984 0.300 ENST00000468739.1
SPRR2F
small proline-rich protein 2F
chr10_-_95241951 0.299 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
MYOF


myoferlin


chrX_-_130423200 0.296 ENST00000361420.3
IGSF1
immunoglobulin superfamily, member 1
chr5_+_34757309 0.294 ENST00000397449.1
RAI14
retinoic acid induced 14
chr15_+_52155001 0.294 ENST00000544199.1
TMOD3
tropomodulin 3 (ubiquitous)
chr2_+_234545092 0.294 ENST00000344644.5
UGT1A10
UDP glucuronosyltransferase 1 family, polypeptide A10
chr12_-_11062161 0.291 ENST00000390677.2
TAS2R13
taste receptor, type 2, member 13
chr2_-_161056762 0.290 ENST00000428609.2
ENST00000409967.2
ITGB6

integrin, beta 6

chr1_-_237167718 0.289 ENST00000464121.2
MT1HL1
metallothionein 1H-like 1
chr4_-_69817481 0.288 ENST00000251566.4
UGT2A3
UDP glucuronosyltransferase 2 family, polypeptide A3
chr10_-_126849068 0.283 ENST00000494626.2
ENST00000337195.5
CTBP2

C-terminal binding protein 2

chr12_-_12491608 0.281 ENST00000545735.1
MANSC1
MANSC domain containing 1
chr1_-_146040968 0.280 ENST00000401010.3
NBPF11
neuroblastoma breakpoint family, member 11
chr2_+_234601512 0.279 ENST00000305139.6
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr9_-_116837249 0.279 ENST00000466610.2
AMBP
alpha-1-microglobulin/bikunin precursor
chr13_-_46679185 0.277 ENST00000439329.3
CPB2
carboxypeptidase B2 (plasma)
chr20_-_56286479 0.275 ENST00000265626.4
PMEPA1
prostate transmembrane protein, androgen induced 1
chr13_-_46679144 0.275 ENST00000181383.4
CPB2
carboxypeptidase B2 (plasma)
chr2_-_161056802 0.272 ENST00000283249.2
ENST00000409872.1
ITGB6

integrin, beta 6

chr14_+_61447832 0.269 ENST00000354886.2
ENST00000267488.4
SLC38A6

solute carrier family 38, member 6

chr14_+_23938891 0.264 ENST00000408901.3
ENST00000397154.3
ENST00000555128.1
NGDN


neuroguidin, EIF4E binding protein


chr4_+_70146217 0.264 ENST00000335568.5
ENST00000511240.1
UGT2B28

UDP glucuronosyltransferase 2 family, polypeptide B28

chr12_+_117013656 0.261 ENST00000556529.1
MAP1LC3B2
microtubule-associated protein 1 light chain 3 beta 2
chr11_-_104035088 0.259 ENST00000302251.5
PDGFD
platelet derived growth factor D
chr11_+_44117260 0.257 ENST00000358681.4
EXT2
exostosin glycosyltransferase 2
chr6_+_27114861 0.257 ENST00000377459.1
HIST1H2AH
histone cluster 1, H2ah
chr2_+_234526272 0.255 ENST00000373450.4
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr1_-_153013588 0.252 ENST00000360379.3
SPRR2D
small proline-rich protein 2D
chr11_-_115375107 0.252 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1





cell adhesion molecule 1





chr2_+_234668894 0.249 ENST00000608383.1
ENST00000360418.3
ENST00000305208.5
UGT1A1

UGT1A8
UDP glucuronosyltransferase 1 family, polypeptide A8

UDP glucuronosyltransferase 1 family, polypeptide A1
chr14_+_61447927 0.249 ENST00000451406.1
SLC38A6
solute carrier family 38, member 6
chr7_+_151771377 0.247 ENST00000434507.1
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr4_-_155533787 0.247 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
FGG





fibrinogen gamma chain





chr12_-_28125638 0.246 ENST00000545234.1
PTHLH
parathyroid hormone-like hormone
chrX_+_37208521 0.246 ENST00000378628.4
PRRG1
proline rich Gla (G-carboxyglutamic acid) 1
chr11_-_5255861 0.245 ENST00000380299.3
HBD
hemoglobin, delta
chr7_+_106505696 0.245 ENST00000440650.2
ENST00000496166.1
ENST00000473541.1
PIK3CG


phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma


chr11_+_27062272 0.244 ENST00000529202.1
ENST00000533566.1
BBOX1

butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1

chr5_-_42825983 0.243 ENST00000506577.1
SEPP1
selenoprotein P, plasma, 1
chr22_+_39052632 0.243 ENST00000411557.1
ENST00000396811.2
ENST00000216029.3
ENST00000416285.1
CBY1



chibby homolog 1 (Drosophila)



chr6_-_32145861 0.242 ENST00000336984.6
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr16_-_20556492 0.240 ENST00000568098.1
ACSM2B
acyl-CoA synthetase medium-chain family member 2B
chr2_-_88427568 0.238 ENST00000393750.3
ENST00000295834.3
FABP1

fatty acid binding protein 1, liver

chr9_-_21368075 0.234 ENST00000449498.1
IFNA13
interferon, alpha 13
chr5_-_125930929 0.234 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
ALDH7A1


aldehyde dehydrogenase 7 family, member A1


chr11_+_130029457 0.233 ENST00000278742.5
ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr21_-_30365136 0.232 ENST00000361371.5
ENST00000389194.2
ENST00000389195.2
LTN1


listerin E3 ubiquitin protein ligase 1


chr6_+_151561085 0.232 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr7_-_22234381 0.232 ENST00000458533.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr8_+_104892639 0.230 ENST00000436393.2
RIMS2
regulating synaptic membrane exocytosis 2
chrY_+_15016013 0.230 ENST00000360160.4
ENST00000454054.1
DDX3Y

DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked

chr1_+_152881014 0.230 ENST00000368764.3
ENST00000392667.2
IVL

involucrin

chr4_-_143226979 0.230 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr8_+_40010989 0.229 ENST00000315792.3
C8orf4
chromosome 8 open reading frame 4
chr3_-_99569821 0.229 ENST00000487087.1
FILIP1L
filamin A interacting protein 1-like
chr4_-_101439148 0.228 ENST00000511970.1
ENST00000502569.1
ENST00000305864.3
EMCN


endomucin


chr9_+_123970052 0.228 ENST00000373823.3
GSN
gelsolin
chr6_+_143999072 0.227 ENST00000440869.2
ENST00000367582.3
ENST00000451827.2
PHACTR2


phosphatase and actin regulator 2


chr19_+_45449228 0.225 ENST00000252490.4
APOC2
apolipoprotein C-II
chr1_-_153029980 0.225 ENST00000392653.2
SPRR2A
small proline-rich protein 2A
chr4_-_144940477 0.224 ENST00000513128.1
ENST00000429670.2
ENST00000502664.1
GYPB


glycophorin B (MNS blood group)


chr7_+_142458507 0.224 ENST00000492062.1
PRSS1
protease, serine, 1 (trypsin 1)
chr7_+_120629653 0.223 ENST00000450913.2
ENST00000340646.5
CPED1

cadherin-like and PC-esterase domain containing 1

chr17_+_79650962 0.222 ENST00000329138.4
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr18_+_29171689 0.221 ENST00000237014.3
TTR
transthyretin
chr20_+_34802295 0.220 ENST00000432603.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr12_-_14996355 0.219 ENST00000228936.4
ART4
ADP-ribosyltransferase 4 (Dombrock blood group)
chr5_+_140593509 0.219 ENST00000341948.4
PCDHB13
protocadherin beta 13
chr16_-_66764119 0.215 ENST00000569320.1
DYNC1LI2
dynein, cytoplasmic 1, light intermediate chain 2
chrX_+_30261847 0.211 ENST00000378981.3
ENST00000397550.1
MAGEB1

melanoma antigen family B, 1

chr19_+_45449266 0.211 ENST00000592257.1
APOC2
apolipoprotein C-II
chr20_+_56136136 0.210 ENST00000319441.4
ENST00000543666.1
PCK1

phosphoenolpyruvate carboxykinase 1 (soluble)

chr19_-_43382142 0.210 ENST00000597058.1
PSG1
pregnancy specific beta-1-glycoprotein 1
chr18_-_61329118 0.209 ENST00000332821.8
ENST00000283752.5
SERPINB3

serpin peptidase inhibitor, clade B (ovalbumin), member 3

chr7_-_76247617 0.209 ENST00000441393.1
POMZP3
POM121 and ZP3 fusion
chr16_-_55867146 0.207 ENST00000422046.2
CES1
carboxylesterase 1
chr1_+_144151520 0.207 ENST00000369372.4
NBPF8
neuroblastoma breakpoint family, member 8
chr16_-_18462221 0.206 ENST00000528301.1
RP11-1212A22.4
LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chr22_+_21133469 0.205 ENST00000406799.1
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr11_+_27076764 0.205 ENST00000525090.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr4_-_11431389 0.205 ENST00000002596.5
HS3ST1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr11_-_46722117 0.204 ENST00000311956.4
ARHGAP1
Rho GTPase activating protein 1
chr12_+_57984965 0.203 ENST00000540759.2
ENST00000551772.1
ENST00000550465.1
ENST00000354947.5
PIP4K2C



phosphatidylinositol-5-phosphate 4-kinase, type II, gamma



chr17_-_26694979 0.203 ENST00000438614.1
VTN
vitronectin
chr7_-_80551671 0.203 ENST00000419255.2
ENST00000544525.1
SEMA3C

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C

chr16_-_66584059 0.202 ENST00000417693.3
ENST00000544898.1
ENST00000569718.1
ENST00000527284.1
ENST00000299697.7
ENST00000451102.2
TK2





thymidine kinase 2, mitochondrial





chr19_+_51728316 0.202 ENST00000436584.2
ENST00000421133.2
ENST00000391796.3
ENST00000262262.4
CD33



CD33 molecule



chr10_+_5238793 0.202 ENST00000263126.1
AKR1C4
aldo-keto reductase family 1, member C4
chr5_+_140227048 0.202 ENST00000532602.1
PCDHA9
protocadherin alpha 9
chr1_+_207262881 0.200 ENST00000451804.2
C4BPB
complement component 4 binding protein, beta

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.3 1.6 GO:0006789 bilirubin conjugation(GO:0006789) biphenyl metabolic process(GO:0018879) biphenyl catabolic process(GO:0070980)
0.3 1.6 GO:0043312 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.3 0.8 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902) positive regulation of phospholipid catabolic process(GO:0060697)
0.3 1.0 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.2 0.7 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.2 0.6 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.2 0.6 GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.2 0.7 GO:0060649 nipple development(GO:0060618) mammary gland bud elongation(GO:0060649) nipple morphogenesis(GO:0060658) nipple sheath formation(GO:0060659)
0.2 0.6 GO:0051552 flavone metabolic process(GO:0051552)
0.1 0.4 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.1 0.5 GO:0051503 purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503)
0.1 0.5 GO:0071400 cellular response to oleic acid(GO:0071400)
0.1 0.4 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.1 0.5 GO:0001575 globoside metabolic process(GO:0001575)
0.1 0.5 GO:0050653 UDP-N-acetylgalactosamine metabolic process(GO:0019276) chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 1.1 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.1 0.6 GO:0060242 contact inhibition(GO:0060242)
0.1 3.1 GO:0031424 keratinization(GO:0031424)
0.1 0.5 GO:0006927 obsolete transformed cell apoptotic process(GO:0006927)
0.1 0.4 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 0.4 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 2.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.3 GO:0006530 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.1 1.2 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1 1.1 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.1 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.4 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.2 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 0.3 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.1 0.2 GO:2000105 positive regulation of DNA-dependent DNA replication initiation(GO:0032298) positive regulation of DNA-dependent DNA replication(GO:2000105)
0.1 0.3 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.1 GO:0002675 positive regulation of acute inflammatory response(GO:0002675)
0.1 0.3 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.2 GO:0032071 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922) regulation of endodeoxyribonuclease activity(GO:0032071) negative regulation of nuclease activity(GO:0032074)
0.1 1.7 GO:0006693 prostaglandin metabolic process(GO:0006693)
0.1 0.1 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.1 0.6 GO:0045329 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.1 0.6 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.3 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.2 GO:0046102 nicotinamide riboside catabolic process(GO:0006738) inosine metabolic process(GO:0046102) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.1 0.2 GO:0019695 choline metabolic process(GO:0019695)
0.1 0.2 GO:0060729 negative regulation of interleukin-23 production(GO:0032707) intestinal epithelial structure maintenance(GO:0060729)
0.1 0.2 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.1 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.2 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.1 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.3 GO:0000050 urea cycle(GO:0000050)
0.0 0.8 GO:0042730 fibrinolysis(GO:0042730)
0.0 1.8 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.0 0.4 GO:0015886 heme transport(GO:0015886)
0.0 1.3 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.3 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.4 GO:0010658 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.9 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.8 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.4 GO:0051014 actin filament severing(GO:0051014)
0.0 0.6 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.0 GO:0019627 urea metabolic process(GO:0019627)
0.0 0.1 GO:0006726 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.1 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.0 0.1 GO:0072205 collecting duct development(GO:0072044) metanephric collecting duct development(GO:0072205)
0.0 1.1 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.5 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.1 GO:0045750 obsolete positive regulation of S phase of mitotic cell cycle(GO:0045750)
0.0 0.2 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.3 GO:0060907 cGMP-mediated signaling(GO:0019934) regulation of phagocytosis, engulfment(GO:0060099) positive regulation of phagocytosis, engulfment(GO:0060100) positive regulation of macrophage cytokine production(GO:0060907) regulation of membrane invagination(GO:1905153) positive regulation of membrane invagination(GO:1905155)
0.0 0.4 GO:0046697 decidualization(GO:0046697)
0.0 0.3 GO:0050892 intestinal absorption(GO:0050892)
0.0 0.2 GO:0046968 peptide antigen transport(GO:0046968)
0.0 0.7 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0046621 negative regulation of organ growth(GO:0046621)
0.0 0.5 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.1 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.0 0.3 GO:0002347 response to tumor cell(GO:0002347)
0.0 0.3 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.1 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.4 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of wound healing(GO:0061045) negative regulation of hemostasis(GO:1900047)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.2 GO:0006654 positive regulation of cytokine-mediated signaling pathway(GO:0001961) phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0034442 plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0 0.8 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.9 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 3.1 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.1 GO:0042519 tyrosine phosphorylation of Stat4 protein(GO:0042504) regulation of tyrosine phosphorylation of Stat4 protein(GO:0042519) positive regulation of tyrosine phosphorylation of Stat4 protein(GO:0042520)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0072284 visceral serous pericardium development(GO:0061032) S-shaped body morphogenesis(GO:0072050) metanephric S-shaped body morphogenesis(GO:0072284)
0.0 0.1 GO:1903960 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0 0.2 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415) regulation of skeletal muscle tissue regeneration(GO:0043416)
0.0 0.3 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.2 GO:0006525 arginine metabolic process(GO:0006525)
0.0 0.1 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.3 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.3 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.1 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.1 GO:0035120 post-embryonic appendage morphogenesis(GO:0035120)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.4 GO:0008206 bile acid metabolic process(GO:0008206)
0.0 0.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.7 GO:0030837 negative regulation of actin filament polymerization(GO:0030837)
0.0 0.3 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0030277 epithelial structure maintenance(GO:0010669) maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.1 GO:0007549 dosage compensation(GO:0007549)
0.0 0.1 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.1 GO:0001845 phagolysosome assembly(GO:0001845) post-embryonic organ morphogenesis(GO:0048563) phagosome maturation(GO:0090382)
0.0 0.2 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.1 GO:0043267 negative regulation of potassium ion transport(GO:0043267)
0.0 0.2 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) cell death in response to oxidative stress(GO:0036473)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.0 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.0 0.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.2 GO:0006862 nucleotide transport(GO:0006862)
0.0 0.0 GO:0034036 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.2 GO:0048261 negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 0.1 GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein(GO:0042517)
0.0 0.0 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.1 GO:0051294 establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0009629 response to gravity(GO:0009629)
0.0 0.2 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.1 GO:0002885 positive regulation of hypersensitivity(GO:0002885)
0.0 0.0 GO:0032621 interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.0 0.1 GO:0006553 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.0 GO:0006577 amino-acid betaine metabolic process(GO:0006577) carnitine metabolic process(GO:0009437)
0.0 0.2 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.0 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.1 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.0 GO:0009103 lipopolysaccharide biosynthetic process(GO:0009103)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.3 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.1 GO:0042940 D-amino acid transport(GO:0042940) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.0 GO:0070265 necrotic cell death(GO:0070265)
0.0 0.1 GO:0061339 establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.1 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.0 0.3 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.1 GO:0010226 response to lithium ion(GO:0010226)
0.0 0.1 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.2 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.6 GO:0061025 membrane fusion(GO:0061025)
0.0 0.0 GO:0060423 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047) iris morphogenesis(GO:0061072) cornea development in camera-type eye(GO:0061303)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.2 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.1 GO:0046519 sphingoid metabolic process(GO:0046519)
0.0 0.1 GO:0051546 keratinocyte migration(GO:0051546)
0.0 0.2 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 0.9 GO:0009986 cell surface(GO:0009986)
0.3 0.9 GO:0005610 laminin-5 complex(GO:0005610)
0.1 1.6 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 3.7 GO:0001533 cornified envelope(GO:0001533)
0.1 2.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.8 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 1.5 GO:0005606 laminin-1 complex(GO:0005606)
0.1 0.5 GO:0005916 fascia adherens(GO:0005916)
0.1 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.0 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.2 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.4 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.1 GO:0016235 aggresome(GO:0016235)
0.1 0.2 GO:0032585 multivesicular body membrane(GO:0032585)
0.1 0.5 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.5 GO:0042627 chylomicron(GO:0042627)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.1 GO:0000776 kinetochore(GO:0000776)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.0 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.8 GO:0005776 autophagosome(GO:0005776)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.1 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 6.8 GO:0005792 obsolete microsome(GO:0005792)
0.0 0.3 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.3 GO:0030122 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.0 GO:0000802 transverse filament(GO:0000802)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.4 GO:0005844 polysome(GO:0005844)
0.0 0.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 2.6 GO:0005925 focal adhesion(GO:0005925)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.5 GO:0045095 keratin filament(GO:0045095)
0.0 0.0 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.4 GO:0031526 brush border membrane(GO:0031526)
0.0 0.0 GO:0005839 proteasome core complex(GO:0005839)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0047718 indanol dehydrogenase activity(GO:0047718)
0.4 1.6 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.4 1.1 GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.4 1.9 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.3 1.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.3 1.0 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 0.2 GO:0047042 androsterone dehydrogenase (B-specific) activity(GO:0047042)
0.2 6.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 0.6 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.4 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 0.9 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 1.1 GO:0008527 taste receptor activity(GO:0008527)
0.1 0.3 GO:0004797 thymidine kinase activity(GO:0004797)
0.1 0.2 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.1 3.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.4 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1 0.4 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.4 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 1.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.0 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.4 GO:0080030 methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.1 0.6 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.2 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.1 0.3 GO:0019862 IgA binding(GO:0019862)
0.1 0.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.4 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989)
0.1 0.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.3 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.3 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.1 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.3 GO:0034711 inhibin binding(GO:0034711)
0.1 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.5 GO:1901567 icosanoid binding(GO:0050542) icosatetraenoic acid binding(GO:0050543) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.1 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.5 GO:0016595 glutamate binding(GO:0016595)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.6 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.4 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.6 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.5 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.9 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.4 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.2 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.4 GO:0046934 obsolete inositol or phosphatidylinositol kinase activity(GO:0004428) phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.5 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.2 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.0 0.1 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 3.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.0 0.3 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.2 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.9 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.3 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.1 GO:0004608 phosphatidylethanolamine N-methyltransferase activity(GO:0004608)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.4 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.2 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.1 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.1 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0035240 dopamine binding(GO:0035240)
0.0 0.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.3 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.4 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.1 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0017057 glucose-6-phosphate dehydrogenase activity(GO:0004345) 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:0009384 N-acylmannosamine kinase activity(GO:0009384)
0.0 0.1 GO:0004461 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) lactose synthase activity(GO:0004461)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.1 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.0 0.1 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.1 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.0 0.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.1 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.2 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.5 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0051378 serotonin binding(GO:0051378)
0.0 0.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.0 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.0 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.0 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0 0.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.0 GO:0016803 ether hydrolase activity(GO:0016803) hepoxilin-epoxide hydrolase activity(GO:0047977) arachidonate 15-lipoxygenase activity(GO:0050473)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.2 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.0 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.4 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.0 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.1 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.2 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.0 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.4 GO:0019843 rRNA binding(GO:0019843)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 2.1 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.1 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.3 GO:0008373 sialyltransferase activity(GO:0008373)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.7 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.6 ST_GA13_PATHWAY G alpha 13 Pathway