Motif ID: HOXD1

Z-value: 0.871


Transcription factors associated with HOXD1:

Gene SymbolEntrez IDGene Name
HOXD1 ENSG00000128645.11 HOXD1



Activity profile for motif HOXD1.

activity profile for motif HOXD1


Sorted Z-values histogram for motif HOXD1

Sorted Z-values for motif HOXD1



Network of associatons between targets according to the STRING database.



First level regulatory network of HOXD1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_55563072 1.136 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
 RAB27A


RAB27A, member RAS oncogene family


chr11_-_62521614 1.124 ENST00000527994.1
ENST00000394807.3
 ZBTB3

zinc finger and BTB domain containing 3

chr15_-_55562479 1.073 ENST00000564609.1
 RAB27A
RAB27A, member RAS oncogene family
chr8_-_49834299 1.018 ENST00000396822.1
 SNAI2
snail family zinc finger 2
chr4_-_25865159 1.003 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
 SEL1L3



sel-1 suppressor of lin-12-like 3 (C. elegans)



chr12_+_29376673 0.966 ENST00000547116.1
 FAR2
fatty acyl CoA reductase 2
chr12_+_29376592 0.952 ENST00000182377.4
 FAR2
fatty acyl CoA reductase 2
chr3_-_151034734 0.932 ENST00000260843.4
 GPR87
G protein-coupled receptor 87
chr8_-_49833978 0.906 ENST00000020945.1
 SNAI2
snail family zinc finger 2
chr11_-_102651343 0.868 ENST00000279441.4
ENST00000539681.1
 MMP10

matrix metallopeptidase 10 (stromelysin 2)

chr12_-_10022735 0.724 ENST00000228438.2
 CLEC2B
C-type lectin domain family 2, member B
chr15_-_55562582 0.723 ENST00000396307.2
 RAB27A
RAB27A, member RAS oncogene family
chr11_-_71823266 0.622 ENST00000538919.1
ENST00000539395.1
ENST00000542531.1
 ANAPC15


anaphase promoting complex subunit 15


chr12_+_28410128 0.579 ENST00000381259.1
ENST00000381256.1
 CCDC91

coiled-coil domain containing 91

chr5_+_66300446 0.576 ENST00000261569.7
 MAST4
microtubule associated serine/threonine kinase family member 4
chrX_+_43515467 0.552 ENST00000338702.3
ENST00000542639.1
 MAOA

monoamine oxidase A

chr11_-_71823796 0.520 ENST00000545680.1
ENST00000543587.1
ENST00000538393.1
ENST00000535234.1
ENST00000227618.4
ENST00000535503.1
 ANAPC15





anaphase promoting complex subunit 15





chr11_-_71823715 0.470 ENST00000545944.1
ENST00000502597.2
 ANAPC15

anaphase promoting complex subunit 15

chr7_-_81399438 0.455 ENST00000222390.5
 HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr3_+_111717600 0.447 ENST00000273368.4
 TAGLN3
transgelin 3
chr7_-_81399329 0.447 ENST00000453411.1
ENST00000444829.2
 HGF

hepatocyte growth factor (hepapoietin A; scatter factor)

chrX_+_114827818 0.412 ENST00000420625.2
 PLS3
plastin 3
chr3_+_111717511 0.408 ENST00000478951.1
ENST00000393917.2
 TAGLN3

transgelin 3

chr15_-_37393406 0.375 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
 MEIS2


Meis homeobox 2


chr3_+_111718036 0.348 ENST00000455401.2
 TAGLN3
transgelin 3
chr12_-_118797475 0.347 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
 TAOK3


TAO kinase 3


chr3_-_126327398 0.346 ENST00000383572.2
 TXNRD3NB
thioredoxin reductase 3 neighbor
chr5_+_148737562 0.343 ENST00000274569.4
 PCYOX1L
prenylcysteine oxidase 1 like
chr7_-_81399411 0.297 ENST00000423064.2
 HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr7_-_81399355 0.249 ENST00000457544.2
 HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr3_-_164796269 0.220 ENST00000264382.3
 SI
sucrase-isomaltase (alpha-glucosidase)
chr3_+_111718173 0.216 ENST00000494932.1
 TAGLN3
transgelin 3
chr18_-_33709268 0.164 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
 SLC39A6


solute carrier family 39 (zinc transporter), member 6


chrX_+_77154935 0.152 ENST00000481445.1
 COX7B
cytochrome c oxidase subunit VIIb
chr11_+_73498898 0.102 ENST00000535529.1
ENST00000497094.2
ENST00000411840.2
ENST00000535277.1
ENST00000398483.3
ENST00000542303.1
 MRPL48





mitochondrial ribosomal protein L48





chr2_+_11682790 0.094 ENST00000389825.3
ENST00000381483.2
 GREB1

growth regulation by estrogen in breast cancer 1

chr7_-_99716952 0.092 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
 TAF6










TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa










chr5_+_176811431 0.083 ENST00000512593.1
ENST00000324417.5
 SLC34A1

solute carrier family 34 (type II sodium/phosphate contransporter), member 1

chr4_+_144354644 0.062 ENST00000512843.1
 GAB1
GRB2-associated binding protein 1
chr3_-_101039402 0.040 ENST00000193391.7
 IMPG2
interphotoreceptor matrix proteoglycan 2
chr4_-_119759795 0.038 ENST00000419654.2
 SEC24D
SEC24 family member D
chr17_-_10372875 0.028 ENST00000255381.2
 MYH4
myosin, heavy chain 4, skeletal muscle
chr10_+_18549645 0.021 ENST00000396576.2
 CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr4_-_74486347 0.016 ENST00000342081.3
 RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr9_-_5339873 0.012 ENST00000223862.1
ENST00000223858.4
 RLN1

relaxin 1

chr4_-_74486217 0.009 ENST00000335049.5
ENST00000307439.5
 RASSF6

Ras association (RalGDS/AF-6) domain family member 6

chr3_+_129247479 0.005 ENST00000296271.3
 RHO
rhodopsin
chr14_+_32798547 0.005 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
 AKAP6


A kinase (PRKA) anchor protein 6


chr11_-_95657231 0.003 ENST00000409459.1
ENST00000352297.7
ENST00000393223.3
ENST00000346299.5
 MTMR2



myotubularin related protein 2




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.9 GO:0043316 natural killer cell activation involved in immune response(GO:0002323) cytotoxic T cell degranulation(GO:0043316) natural killer cell degranulation(GO:0043320)
0.3 1.9 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.3 1.9 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.2 1.4 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.6 GO:0042420 dopamine catabolic process(GO:0042420)
0.1 0.3 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.9 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0055062 phosphate ion homeostasis(GO:0055062) divalent inorganic anion homeostasis(GO:0072505) trivalent inorganic anion homeostasis(GO:0072506)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.9 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 2.9 GO:0030667 secretory granule membrane(GO:0030667)
0.0 1.4 GO:0034774 platelet alpha granule lumen(GO:0031093) secretory granule lumen(GO:0034774)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0050062 long-chain-fatty-acyl-CoA reductase activity(GO:0050062)
0.3 2.9 GO:0031489 myosin V binding(GO:0031489)
0.1 0.6 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.3 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.2 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.0 0.9 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)