Motif ID: INSM1
Z-value: 0.898
Transcription factors associated with INSM1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| INSM1 | ENSG00000173404.3 | INSM1 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.8 | 5.3 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
| 0.5 | 1.6 | GO:0033578 | protein glycosylation in Golgi(GO:0033578) |
| 0.3 | 1.2 | GO:0051573 | negative regulation of histone H3-K9 methylation(GO:0051573) |
| 0.2 | 0.9 | GO:0033602 | negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of dopamine secretion(GO:0033602) |
| 0.2 | 0.5 | GO:0035461 | vitamin transmembrane transport(GO:0035461) |
| 0.2 | 0.5 | GO:0033590 | response to cobalamin(GO:0033590) |
| 0.1 | 0.4 | GO:0006273 | lagging strand elongation(GO:0006273) |
| 0.1 | 0.6 | GO:0030382 | sperm mitochondrion organization(GO:0030382) |
| 0.1 | 0.4 | GO:0045603 | positive regulation of endothelial cell differentiation(GO:0045603) |
| 0.1 | 0.5 | GO:0010157 | response to chlorate(GO:0010157) |
| 0.1 | 0.4 | GO:0032776 | DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116) |
| 0.1 | 0.3 | GO:0014887 | muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898) |
| 0.1 | 0.4 | GO:0016561 | protein import into peroxisome matrix, translocation(GO:0016561) |
| 0.1 | 0.6 | GO:0043923 | positive regulation by host of viral transcription(GO:0043923) |
| 0.1 | 0.5 | GO:0048302 | negative regulation of type 2 immune response(GO:0002829) isotype switching to IgG isotypes(GO:0048291) regulation of isotype switching to IgG isotypes(GO:0048302) |
| 0.1 | 0.2 | GO:0008300 | isoprenoid catabolic process(GO:0008300) |
| 0.0 | 0.8 | GO:0060736 | prostate gland growth(GO:0060736) |
| 0.0 | 0.4 | GO:0030903 | notochord development(GO:0030903) |
| 0.0 | 0.1 | GO:0019348 | polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348) |
| 0.0 | 0.3 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
| 0.0 | 0.1 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 0.0 | 0.4 | GO:0051085 | chaperone mediated protein folding requiring cofactor(GO:0051085) |
| 0.0 | 0.2 | GO:0035455 | response to interferon-alpha(GO:0035455) |
| 0.0 | 0.7 | GO:0071479 | cellular response to ionizing radiation(GO:0071479) |
| 0.0 | 0.4 | GO:0019228 | neuronal action potential(GO:0019228) |
| 0.0 | 0.3 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.0 | 0.3 | GO:0046037 | phototransduction, visible light(GO:0007603) GMP metabolic process(GO:0046037) |
| 0.0 | 2.2 | GO:0007605 | sensory perception of sound(GO:0007605) |
| 0.0 | 0.1 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
| 0.0 | 0.5 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280) negative regulation of lyase activity(GO:0051350) |
| 0.0 | 0.1 | GO:0001544 | initiation of primordial ovarian follicle growth(GO:0001544) |
| 0.0 | 1.9 | GO:0051092 | positive regulation of NF-kappaB transcription factor activity(GO:0051092) |
| 0.0 | 0.1 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
| 0.0 | 0.1 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
| 0.0 | 0.6 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
| 0.0 | 1.3 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
| 0.0 | 0.1 | GO:1901984 | negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757) |
| 0.0 | 0.2 | GO:0030219 | megakaryocyte differentiation(GO:0030219) |
| 0.0 | 0.1 | GO:0060391 | positive regulation of SMAD protein import into nucleus(GO:0060391) |
| 0.0 | 0.1 | GO:0032916 | transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.9 | GO:0030673 | axolemma(GO:0030673) |
| 0.1 | 5.2 | GO:0016605 | PML body(GO:0016605) |
| 0.1 | 0.2 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.1 | 0.8 | GO:0030130 | clathrin coat of trans-Golgi network vesicle(GO:0030130) |
| 0.1 | 0.4 | GO:0042575 | DNA polymerase complex(GO:0042575) |
| 0.0 | 0.4 | GO:0000791 | euchromatin(GO:0000791) |
| 0.0 | 0.1 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.0 | 0.3 | GO:0032039 | integrator complex(GO:0032039) |
| 0.0 | 0.2 | GO:0032590 | dendrite membrane(GO:0032590) |
| 0.0 | 0.6 | GO:0031514 | motile cilium(GO:0031514) |
| 0.0 | 0.2 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.0 | 1.3 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.0 | 0.1 | GO:0071256 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 0.0 | 0.5 | GO:0031526 | brush border membrane(GO:0031526) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.8 | 5.3 | GO:0008310 | single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) exoribonuclease II activity(GO:0008859) |
| 0.5 | 1.6 | GO:0008424 | glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921) |
| 0.3 | 0.9 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
| 0.2 | 1.3 | GO:0001515 | opioid peptide activity(GO:0001515) |
| 0.2 | 0.5 | GO:0008523 | sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) |
| 0.2 | 0.5 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |
| 0.1 | 0.4 | GO:0008296 | 3'-5'-exodeoxyribonuclease activity(GO:0008296) |
| 0.1 | 0.4 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
| 0.1 | 1.5 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.1 | 1.2 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.1 | 0.5 | GO:0001641 | group II metabotropic glutamate receptor activity(GO:0001641) |
| 0.1 | 0.5 | GO:0005113 | patched binding(GO:0005113) |
| 0.1 | 0.4 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.1 | 0.6 | GO:0016671 | oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671) |
| 0.1 | 0.8 | GO:0030276 | clathrin binding(GO:0030276) |
| 0.0 | 0.1 | GO:0047391 | alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391) |
| 0.0 | 0.1 | GO:0000150 | recombinase activity(GO:0000150) |
| 0.0 | 0.5 | GO:0042301 | phosphate ion binding(GO:0042301) |
| 0.0 | 0.7 | GO:0043560 | insulin receptor substrate binding(GO:0043560) |
| 0.0 | 0.2 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.0 | 0.2 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) |
| 0.0 | 0.4 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.0 | 0.1 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
| 0.0 | 0.3 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.0 | 0.1 | GO:0016647 | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647) |
| 0.0 | 0.1 | GO:0043175 | RNA polymerase core enzyme binding(GO:0043175) |
| 0.0 | 0.1 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.0 | 0.0 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | ST_TUMOR_NECROSIS_FACTOR_PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 0.3 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
